Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncyclosporin A binding

PPIAL4C PPIAL4H PPIB PPIAL4A PPIAL4G

2.20e-06241825GO:0016018
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 COL14A1

3.65e-06461826GO:0030020
GeneOntologyMolecularFunctionopsonin binding

APCS ITGB2 C4A C4B

7.27e-05251824GO:0001846
GeneOntologyMolecularFunctioncomplement component C1q complex binding

APCS C4A C4B

8.53e-05101823GO:0001849
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

PPIAL4C PPIAL4H PPIB PPIAL4A PPIAL4G

9.05e-05501825GO:0003755
GeneOntologyMolecularFunctioncis-trans isomerase activity

PPIAL4C PPIAL4H PPIB PPIAL4A PPIAL4G

1.20e-04531825GO:0016859
GeneOntologyMolecularFunctioncomplement binding

APCS ITGB2 C4A C4B

1.97e-04321824GO:0001848
GeneOntologyMolecularFunctionoxidoreductase activity

ALKBH4 MICAL1 CYP2C18 MAOA CYP2F1 GPX8 ACAD9 PARK7 PYROXD2 RDH5 ALDH1L1 NDUFB6 CRYL1 ALDH1A2 TPH2 ALDH9A1 G6PD CYB5R1

2.31e-0476618218GO:0016491
GeneOntologyMolecularFunctionantiporter activity

SLC24A5 SLC35E2B SLC30A2 SLC30A5 SLC24A4 SLC22A8 SLC37A2

2.77e-041381827GO:0015297
GeneOntologyMolecularFunctionaldehyde dehydrogenase (NAD+) activity

ALDH1L1 ALDH1A2 ALDH9A1

3.13e-04151823GO:0004029
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 HAPLN1 AEBP1 COL14A1

3.37e-041881828GO:0005201
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC24A5 SLC35E2B SLC30A2 SLC38A2 SLC30A5 SLC12A2 SLC24A4 SLC22A8 SLC37A2 CTNS

4.00e-0429618210GO:0015291
GeneOntologyMolecularFunctionaldehyde dehydrogenase [NAD(P)+] activity

ALDH1L1 ALDH1A2 ALDH9A1

4.61e-04171823GO:0004030
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC24A5 SLC30A2 SLC30A5 SLC24A4

6.24e-04431824GO:0140828
GeneOntologyMolecularFunctioncalcium, potassium:sodium antiporter activity

SLC24A5 SLC24A4

8.11e-0451822GO:0008273
GeneOntologyMolecularFunctionzinc:proton antiporter activity

SLC30A2 SLC30A5

8.11e-0451822GO:0140826
GeneOntologyBiologicalProcessorganophosphate metabolic process

PITPNM2 COL6A1 DPYS CAD HK1 ACACB PARK7 ALDH1L1 NDUFB6 PLA2G15 FCSK CRYL1 SLC30A5 PMVK P2RX7 LIPG NT5C2 GPCPD1 SLC37A2 PLA2G6 XYLB PLCG2 CTNS PLD2 G6PD ENTPD8

6.30e-06114217926GO:0019637
GeneOntologyBiologicalProcessorganophosphate catabolic process

COL6A1 DPYS HK1 PLA2G15 P2RX7 LIPG NT5C2 GPCPD1 PLA2G6 PLCG2 PLD2 ENTPD8

6.66e-0628117912GO:0046434
GeneOntologyBiologicalProcessphospholipid catabolic process

PLA2G15 LIPG GPCPD1 PLA2G6 PLCG2 PLD2

1.33e-05601796GO:0009395
GeneOntologyBiologicalProcessprotein peptidyl-prolyl isomerization

PPIAL4C PPIAL4H PPIB PPIAL4A PPIAL4G

1.85e-05381795GO:0000413
GeneOntologyCellularComponentanchoring collagen complex

COL7A1 COL12A1 COL14A1

6.49e-0731823GO:0030934
GeneOntologyCellularComponentcollagen trimer

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 COL14A1

1.20e-04881826GO:0005581
MousePhenodecreased bone mineralization

FLNB COL11A1 COL12A1 EBF1 PPIB ITGB2

1.08e-05511396MP:0020137
DomainVWF_A

VWA5B2 COL6A1 COL7A1 COL12A1 COL6A6 ITGB2 ITGB7 COL14A1

4.56e-06991778IPR002035
Domain-

COL6A1 COL7A1 COL12A1 COL6A6 ITGB2 ITGB7 COL14A1

6.43e-067417773.40.50.410
DomainVWFA

COL6A1 COL7A1 COL12A1 COL6A6 ITGB2 ITGB7 COL14A1

1.27e-05821777PS50234
DomainVWA

COL6A1 COL7A1 COL12A1 COL6A6 ITGB2 ITGB7 COL14A1

1.49e-05841777SM00327
DomainCyclophilin-type_PPIase_CS

PPIAL4C PPIB PPIAL4A PPIAL4G

2.70e-05191774IPR020892
DomainCyclophilin-type_PPIase

PPIAL4C PPIB PPIAL4A PPIAL4G

4.11e-05211774IPR024936
DomainPro_isomerase

PPIAL4C PPIB PPIAL4A PPIAL4G

4.99e-05221774PF00160
DomainCyclophilin-type_PPIase_dom

PPIAL4C PPIB PPIAL4A PPIAL4G

4.99e-05221774IPR002130
DomainCyclophilin-like_dom

PPIAL4C PPIB PPIAL4A PPIAL4G

4.99e-05221774IPR029000
DomainCSA_PPIASE_2

PPIAL4C PPIB PPIAL4A PPIAL4G

4.99e-05221774PS50072
Domain-

PPIAL4C PPIB PPIAL4A PPIAL4G

4.99e-052217742.40.100.10
DomainCSA_PPIASE_1

PPIAL4C PPIB PPIAL4A PPIAL4G

4.99e-05221774PS00170
DomainCollagen

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 COL14A1

1.57e-04851776IPR008160
DomainCollagen

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 COL14A1

1.57e-04851776PF01391
DomainVWA

COL6A1 COL7A1 COL12A1 COL6A6 COL14A1

1.87e-04561775PF00092
Domain-

PAPPA2 FAT4 COL11A1 COL12A1 APCS ADGRV1

2.88e-049517762.60.120.200
DomainAld_DH_CS_GLU

ALDH1L1 ALDH1A2 ALDH9A1

4.28e-04161773IPR029510
DomainAld_DH_CS_CYS

ALDH1L1 ALDH1A2 ALDH9A1

5.16e-04171773IPR016160
DomainALDEHYDE_DEHYDR_CYS

ALDH1L1 ALDH1A2 ALDH9A1

6.15e-04181773PS00070
DomainALDEHYDE_DEHYDR_GLU

ALDH1L1 ALDH1A2 ALDH9A1

6.15e-04181773PS00687
Domain-

ALDH1L1 ALDH1A2 ALDH9A1

7.25e-041917733.40.605.10
DomainAldedh

ALDH1L1 ALDH1A2 ALDH9A1

7.25e-04191773PF00171
DomainAld_DH_C

ALDH1L1 ALDH1A2 ALDH9A1

7.25e-04191773IPR016163
DomainAld_DH_N

ALDH1L1 ALDH1A2 ALDH9A1

7.25e-04191773IPR016162
DomainAld_DH/histidinol_DH

ALDH1L1 ALDH1A2 ALDH9A1

7.25e-04191773IPR016161
DomainAldehyde_DH_dom

ALDH1L1 ALDH1A2 ALDH9A1

7.25e-04191773IPR015590
Domain-

ALDH1L1 ALDH1A2 ALDH9A1

7.25e-041917733.40.309.10
DomainPQ-loop

SLC66A1 CTNS

8.76e-0451772PF04193
DomainAnaphylatoxin_comp_syst

C4A C4B

8.76e-0451772IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

8.76e-0451772IPR001840
DomainCTNS

SLC66A1 CTNS

8.76e-0451772SM00679
DomainCPSASE_1

CAD ACACB

8.76e-0451772PS00866
DomainK/Na/Ca-exchanger

SLC24A5 SLC24A4

8.76e-0451772IPR004481
DomainPQ-loop_rpt

SLC66A1 CTNS

8.76e-0451772IPR006603
DomainConA-like_dom

PAPPA2 FAT4 COL11A1 COL12A1 APCS ADGRV1 RYR1 COL14A1

1.18e-032191778IPR013320
DomainTSPN

COL11A1 COL12A1 COL14A1

1.29e-03231773SM00210
DomainEPTP

ADGRV1 LGI3

1.31e-0361772PF03736
DomainEPTP

ADGRV1 LGI3

1.31e-0361772IPR005492
DomainIntegrin_b_cyt

ITGB2 ITGB7

1.31e-0361772SM01241
DomainIntegrin_b_cyt

ITGB2 ITGB7

1.31e-0361772PF08725
DomainIntegrin_bsu_cyt_dom

ITGB2 ITGB7

1.31e-0361772IPR014836
DomainCPSASE_2

CAD ACACB

1.31e-0361772PS00867
DomainIntegrin_dom

ITGA6 ITGB2 ITGB7

1.65e-03251773IPR032695
DomainANATO

C4A C4B

1.82e-0371772SM00104
DomainCbamoylP_synth_lsu-like_ATP-bd

CAD ACACB

1.82e-0371772IPR005479
DomainANAPHYLATOXIN_2

C4A C4B

1.82e-0371772PS01178
DomainANAPHYLATOXIN_1

C4A C4B

1.82e-0371772PS01177
DomainBC-like_N

CAD ACACB

1.82e-0371772IPR005481
DomainIntegrin_B_tail

ITGB2 ITGB7

1.82e-0371772SM01242
DomainEAR

ADGRV1 LGI3

1.82e-0371772IPR009039
DomainANATO

C4A C4B

1.82e-0371772PF01821
DomainEAR

ADGRV1 LGI3

1.82e-0371772PS50912
DomainIntegrin_bsu_tail

ITGB2 ITGB7

1.82e-0371772IPR012896
DomainCPSase_L_D2

CAD ACACB

1.82e-0371772PF02786
DomainBiotin_carb_N

CAD ACACB

1.82e-0371772PF00289
DomainAnaphylatoxin/fibulin

C4A C4B

1.82e-0371772IPR000020
DomainIntegrin_B_tail

ITGB2 ITGB7

1.82e-0371772PF07965
DomainLaminin_G

FAT4 COL11A1 COL12A1 COL14A1

2.22e-03581774IPR001791
DomainMacrogloblnA2_thiol-ester-bond

C4A C4B

2.41e-0381772IPR019565
DomainINB

ITGB2 ITGB7

2.41e-0381772SM00187
DomainIntegrin_bsu_VWA

ITGB2 ITGB7

2.41e-0381772IPR002369
Domain-

TMEM131 HYDIN

2.41e-03817722.60.40.360
DomainCalx_beta

ADGRV1 FREM3

2.41e-0381772SM00237
DomainIntegrin_beta

ITGB2 ITGB7

2.41e-0381772PF00362
DomainThiol-ester_cl

C4A C4B

2.41e-0381772PF10569
DomainMacrogloblnA2_CS

C4A C4B

2.41e-0381772IPR019742
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 ITGA6 COL14A1

1.70e-06611347M27103
PathwayREACTOME_COLLAGEN_FORMATION

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 ITGA6 PPIB COL14A1

2.18e-06901348M631
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 COL14A1

2.26e-06411346MM15538
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 PPIB COL14A1

3.24e-06671347M26999
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 COL14A1

3.46e-06441346M27812
PathwayPID_SYNDECAN_1_PATHWAY

COL6A1 COL7A1 COL11A1 COL12A1 PPIB COL14A1

4.52e-06461346M198
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 COL14A1

7.43e-06501346MM14796
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 COL14A1

2.38e-05611346MM14637
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL6A1 COL7A1 COL11A1 HTRA1 COL12A1 COL6A6 ITGA6 PPIB ITGB2 ITGB7 HAPLN1 COL14A1

2.88e-0530013412M610
PathwayREACTOME_COLLAGEN_DEGRADATION

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 COL14A1

3.15e-05641346M26953
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL6A1 COL7A1 COL11A1 HTRA1 COL12A1 COL6A6 ITGA6 ITGB2 ITGB7 HAPLN1 COL14A1

3.52e-0525813411MM14572
PathwayKEGG_PYRIMIDINE_METABOLISM

DPYS CAD POLR1A POLD1 POLR2G NT5C2 ENTPD8

4.04e-05981347M5109
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL6A1 COL7A1 COL6A6 ITGA6 ITGB2 ITGB7

8.36e-05761346MM14867
PathwayREACTOME_COLLAGEN_FORMATION

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 COL14A1

8.36e-05761346MM14573
PathwayREACTOME_COLLAGEN_DEGRADATION

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6

1.43e-04531345MM14566
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL6A1 COL7A1 COL6A6 ITGA6 ITGB2 ITGB7

1.56e-04851346M16441
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL6A1 COL7A1 COL11A1 HTRA1 COL12A1 COL6A6 COL14A1

3.77e-041401347M587
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

COL6A1 FLNB DPYS LRRC57 NEBL UACA PARK7 APCS ALDH1L1 ADGRV1 PKD1L3 PPIB RYR1 CRYL1 MYOF PMVK SLC22A8 RNPEP PRKCH CTNS ALDH9A1 SCIN G6PD

4.25e-0910161822319056867
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

PAPPA2 CRISPLD2 COL6A1 FLNB FAT4 NIBAN1 PPIAL4C LRRC57 MAN2B1 PARK7 APCS ALDH1L1 PPIB PLA2G15 CRYL1 MYOF RNPEP PPIAL4A C4A C4B ALDH9A1 G6PD CDH15

1.11e-0810701822323533145
Pubmed

Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.

COL6A1 COL7A1 COL11A1 COL12A1 ITGA6 ITGB2

1.53e-0832182623154389
Pubmed

Small GTPase Rab39A interacts with UACA and regulates the retinoic acid-induced neurite morphology of Neuro2A cells.

UACA RAB39A RAB39B

1.41e-073182323624502
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

FLNB CAD COL12A1 MAN2B1 GPX8 RPS3 ACAD9 PARK7 DLGAP5 TYSND1 PLXNB2 NDUFB6 DRG1 WDR3 SLC38A2 MYOF RNPEP MDC1 NT5C2 ALDH9A1 G6PD PCM1 SYNCRIP

3.50e-0712971822333545068
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

COL6A1 COL11A1 HTRA1 COL12A1 HAPLN1 AEBP1 COL14A1

3.63e-0786182728327460
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FLNB CAD HK1 POLR1A ZCCHC8 HNRNPF WDR3 UTP18 RNPEP MDC1 RBM6 KMT2A HERC2 PCM1 USP47 SYNCRIP

3.93e-076531821622586326
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

POLR1A ACACB COL6A6 ACAD9 POLD1 ALDH1L1 PPIB KMT2A C4A C4B DNAI7 G6PD TBL2 HYDIN

4.17e-074971821436774506
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

COL6A1 HTRA1 COL12A1 APCS HAPLN1 AEBP1 COL14A1

1.09e-06101182720551380
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

COL6A1 HTRA1 COL12A1 APCS HAPLN1 RNPEP AEBP1 COL14A1

1.10e-06146182827068509
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

FLNB CAD HK1 RPS3 PARK7 ALDH1L1 PPIB HNRNPF RYR1 EFTUD2 MYOF SLC12A2 NT5C2 KMT2A G6PD HYDIN SYNCRIP

1.35e-068071821730575818
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

COL11A1 HK1 PARK7 PABPC4L HNRNPF RYR1 UTP18 PMVK KIAA1217 PPIAL4A RAB39A C4A HAL ALDH9A1 G6PD TBL2

1.74e-067321821634732716
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

FLNB CAD UACA ZCCHC8 RPS3 PPP1R9A HNRNPF EFTUD2 RBM6 SYNCRIP

2.03e-062741821034244482
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

FAT4 CAD FRMPD4 RPS3 HNRNPF EFTUD2 LIPG KIAA1217 MDC1 PLA2G6 HERC2 SCIN SYNCRIP

3.49e-065131821325798074
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CYLD CAD HK1 UACA ACAD9 POLD1 PARK7 PLXNB2 PPIB DRG1 EFTUD2 WDR3 SLC38A2 UTP18 SLC12A2 PDZD8 COL14A1 TMEM131 HERC2 ALDH9A1 TBL2 PCM1 SYNCRIP

3.54e-0614871822333957083
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PITPNM2 MICAL1 FLNB HTRA1 CAD HK1 RPS3 PARK7 PPP1R9A ALDH1L1 PPIB SHANK3 HNRNPF HAPLN1 RNPEP KIAA1217 LGI3 KMT2A C4A C4B PCM1 SYNCRIP

6.46e-0614311822237142655
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

COL6A1 COL11A1 HTRA1 COL12A1 PLA2G15 AEBP1 COL14A1 C4A C4B

6.98e-06248182924006456
Pubmed

Loss of Krox20 results in aortic valve regurgitation and impaired transcriptional activation of fibrillar collagen genes.

COL6A1 COL12A1 HAPLN1 COL14A1

7.10e-0624182425344368
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 AEBP1 COL14A1

7.54e-06135182728675934
Pubmed

Temporal and spatial expression of collagens during murine atrioventricular heart valve development and maintenance.

COL11A1 COL12A1 COL14A1

7.74e-068182318816857
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

FLNB NIBAN1 CAD POLR1A RPS3 PPP1R9A PLXNB2 PPIB HNRNPF DRG1 EFTUD2 WDR3 SLC12A2 MDC1 HERC2 SCIN PCM1 SYNCRIP

8.06e-0610241821824711643
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FLNB CAD MIS18BP1 HK1 POLR1A GPX8 RPS3 POLD1 PARK7 DLGAP5 PPIB HNRNPF EFTUD2 WDR3 UTP18 MDC1 PLCG2 HERC2 ALDH9A1 G6PD SYNCRIP

9.23e-0613531822129467282
Pubmed

Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development.

COL6A1 NIBAN1 HTRA1 NEBL HAPLN1 COL14A1 C4A C4B

9.76e-06196182819334288
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

KDELR2 CAD MIS18BP1 HK1 MAOA ZCCHC8 ACAD9 PLXNB2 NFU1 WDR3 UTP18 SLC12A2 KIAA1217 ELAVL2 PDZD8 PRKCH TMEM131 HERC2 TBL2 USP47 CYB5R1 SYNCRIP

1.29e-0514961822232877691
Pubmed

Defining the membrane proteome of NK cells.

NIBAN1 CAD RPS3 POLD1 TYSND1 PPIB ITGB2 ITGB7 HNRNPF DRG1 EFTUD2 KSR1 PMVK PDZD8 HERC2 G6PD PCM1 CYB5R1 SYNCRIP

1.33e-0511681821919946888
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CYLD CAD UACA PARK7 PPP1R9A DLGAP5 HECTD4 PPIB PLA2G15 SHANK3 EFTUD2 P2RX7 KIAA1217 NT5C2 ELAVL2 HERC2 PCM1

1.38e-059631821728671696
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

COL6A1 COL7A1 COL11A1 COL12A1 RAX HAPLN1 AEBP1 PRKCH

1.61e-05210182816537572
Pubmed

Genetic determinants of hair, eye and skin pigmentation in Europeans.

SLC24A5 SLC24A4 HERC2

1.65e-0510182317952075
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

COL6A1 COL7A1 FAT4 HTRA1 COL12A1 MAN2B1 GPX8 ITGA6 PLXNB2 PPIB PLA2G15 DRG1 SLC38A2 MYOF SLC12A2 C4A TMEM131 G6PD AMIGO2

1.95e-0512011821935696571
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

FLNB CAD HK1 POLR1A RPS3 ACAD9 POLD1 PARK7 PPIB PLA2G15 HNRNPF DRG1 EFTUD2 WDR3 SLC38A2 UTP18 RNPEP MDC1 DNAH5 G6PD SYNCRIP

1.99e-0514251822130948266
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

CYLD FLNB POLR1A ACAD9 PARK7 PPP1R9A POLR2G TYSND1 PPIB EFTUD2 WDR3 UTP18 KLHL15 HERC2 ALDH9A1 TBL2 USP47

2.37e-0510051821719615732
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

2.72e-052182222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

2.72e-052182216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

2.72e-052182215998580
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

2.72e-052182219062096
Pubmed

Collagen types XII and XIV are present in basement membrane zones during human embryonic development.

COL12A1 COL14A1

2.72e-052182215609093
Pubmed

Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders.

LRRC57 C4A

2.72e-052182230419947
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

2.72e-052182219933335
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

2.72e-05218222459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

2.72e-052182217645767
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

2.72e-052182212207352
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

2.72e-052182227758680
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

2.72e-052182222387014
Pubmed

Using bioinformatics and systems genetics to dissect HDL-cholesterol genetics in an MRL/MpJ x SM/J intercross.

ABCA1 LIPG

2.72e-052182222498810
Pubmed

Functional analysis of the two reciprocal fusion genes MLL-NEBL and NEBL-MLL reveal their oncogenic potential.

NEBL KMT2A

2.72e-052182223340173
Pubmed

Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a phospholipase D2 pathway.

ABCA1 PLD2

2.72e-052182216118212
Pubmed

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

C4A C4B

2.72e-052182223749435
Pubmed

Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.

C4A C4B

2.72e-052182223918728
Pubmed

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.

C4A C4B

2.72e-05218223037333
Pubmed

Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.

C4A C4B

2.72e-052182211726230
Pubmed

Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.

C4A C4B

2.72e-05218224216347
Pubmed

Sequence determination of the thiolester site of the fourth component of human complement.

C4A C4B

2.72e-05218226950384
Pubmed

Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.

C4A C4B

2.72e-05218228660986
Pubmed

Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.

C4A C4B

2.72e-05218228428773
Pubmed

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

C4A C4B

2.72e-052182224638111
Pubmed

Transcriptional repression of C4 complement by hepatitis C virus proteins.

C4A C4B

2.72e-052182221345967
Pubmed

Novel defects in collagen XII and VI expand the mixed myopathy/Ehlers-Danlos syndrome spectrum and lead to variant-specific alterations in the extracellular matrix.

COL6A1 COL12A1

2.72e-052182231273343
Pubmed

Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

C4A C4B

2.72e-05218222572548
Pubmed

The complement component C4 of mammals.

C4A C4B

2.72e-05218222302180
Pubmed

WIPI-dependent autophagy during neutrophil differentiation of NB4 acute promyelocytic leukemia cells.

WIPI1 WIPI2

2.72e-052182224991767
Pubmed

Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.

C4A C4B

2.72e-052182222151770
Pubmed

C4d-positive chronic rejection: a frequent entity with a poor outcome.

C4A C4B

2.72e-052182218091514
Pubmed

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.

C4A C4B

2.72e-052182229080553
Pubmed

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.

C4A C4B

2.72e-05218226589636
Pubmed

C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.

C4A C4B

2.72e-052182225339671
Pubmed

A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.

C4A C4B

2.72e-052182217728371
Pubmed

Structure and organization of the C4 genes.

C4A C4B

2.72e-05218226149580
Pubmed

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.

C4A C4B

2.72e-05218226149581
Pubmed

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

C4A C4B

2.72e-052182212115608
Pubmed

Biochemistry and biology of anaphylatoxins.

C4A C4B

2.72e-05218223542363
Pubmed

C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.

C4A C4B

2.72e-05218222387317
Pubmed

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.

C4A C4B

2.72e-052182216908004
Pubmed

Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.

C4A C4B

2.72e-05218227365238
Pubmed

Regulation of Integrin α6 Recycling by Calcium-independent Phospholipase A2 (iPLA2) to Promote Microglia Chemotaxis on Laminin.

ITGA6 PLA2G6

2.72e-052182227655917
Pubmed

Retinoic acid receptor-mediated induction of ABCA1 in macrophages.

ABCA1 RARG

2.72e-052182214560020
Pubmed

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.

C4A C4B

2.72e-05218227391573
Pubmed

Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.

C4A C4B

2.72e-052182217971360
Pubmed

The COL12A1 and COL14A1 genes and Achilles tendon injuries.

COL12A1 COL14A1

2.72e-052182217960519
Pubmed

Clinical features of patients with homozygous complement C4A or C4B deficiency.

C4A C4B

2.72e-052182229928053
Pubmed

Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.

C4A C4B

2.72e-052182217971229
Pubmed

Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.

C4A C4B

2.72e-05218226881182
Pubmed

Freeze-fracture replica immunolabelling reveals human WIPI-1 and WIPI-2 as membrane proteins of autophagosomes.

WIPI1 WIPI2

2.72e-052182221564513
Pubmed

Fluorescence-based imaging of autophagy progression by human WIPI protein detection.

WIPI1 WIPI2

2.72e-052182225462558
Pubmed

Partial C4 deficiency in juvenile idiopathic arthritis patients.

C4A C4B

2.72e-052182217921792
Pubmed

Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.

C4A C4B

2.72e-052182221880985
Pubmed

Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.

C4A C4B

2.72e-05218226978711
Pubmed

Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.

C4A C4B

2.72e-052182235898513
Pubmed

Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.

C4A C4B

2.72e-052182228873507
Pubmed

Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.

C4A C4B

2.72e-0521822276882
Pubmed

Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.

C4A C4B

2.72e-05218226832377
Pubmed

Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.

C4A C4B

2.72e-05218223794341
Pubmed

Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.

C4A C4B

2.72e-052182222785613
Pubmed

Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.

C4A C4B

2.72e-052182232691186
Pubmed

The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.

C4A C4B

2.72e-05218228390682
Pubmed

Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).

C4A C4B

2.72e-05218223902619
Pubmed

Structural polymorphism of murine C4 and its linkage to H-2.

C4A C4B

2.72e-05218227373044
Pubmed

The chemical structure of the C4d fragment of the human complement component C4.

C4A C4B

2.72e-05218223696167
Pubmed

Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.

C4A C4B

2.72e-05218221357031
Pubmed

Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.

C4A C4B

2.72e-052182216098595
Pubmed

WIPI β-propellers at the crossroads of autophagosome and lipid droplet dynamics.

WIPI1 WIPI2

2.72e-052182225233424
GeneFamilyCollagens

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 COL14A1

5.97e-07461216490
GeneFamilyPhospholipases

PLA2G15 PLA2G6 PLCG2 PLD2

1.76e-04421214467
GeneFamilyAldehyde dehydrogenases

ALDH1L1 ALDH1A2 ALDH9A1

2.62e-04191213398
GeneFamilySolute carriers

SLC24A5 SLC35E2B SLC30A2 SLC38A2 SLC30A5 SLC12A2 SLC24A4 SLC22A8 SLC37A2 SLC38A8

3.25e-0439512110752
GeneFamilyWD repeat domain containing|UTPB complex

WDR3 UTP18

6.55e-04612121225
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C4A C4B

1.55e-03912121234
GeneFamilyCD molecules|Integrin beta subunits

ITGB2 ITGB7

1.55e-03912121159
GeneFamilyComplement system|Sushi domain containing

ITGB2 C4A C4B

1.78e-03361213492
GeneFamilyWD repeat domain containing

AAMP AHI1 WIPI1 WDR3 UTP18 TBL2 WIPI2

1.92e-032621217362
GeneFamilyPDZ domain containing

HTRA1 FRMPD4 PPP1R9A SHANK3 PDZD8

3.58e-0315212151220
GeneFamilyFibronectin type III domain containing

COL7A1 COL12A1 EPHA6 MYOM1 COL14A1

4.45e-031601215555
GeneFamilyParkinson disease associated genes

PARK7 PLA2G6

5.01e-03161212672
CoexpressionNABA_COLLAGENS

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 COL14A1

4.61e-07431796MM17060
CoexpressionNABA_COLLAGENS

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 COL14A1

5.31e-07441796M3005
CoexpressionNABA_CORE_MATRISOME

VWA5B2 CRISPLD2 COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 HAPLN1 AEBP1 LGI3 COL14A1

2.72e-0627017911MM17057
CoexpressionNABA_CORE_MATRISOME

VWA5B2 CRISPLD2 COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 HAPLN1 AEBP1 LGI3 COL14A1

3.25e-0627517911M5884
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HPERIC

CRISPLD2 COL6A1 NIBAN1 ABCA1 WIPI1 RARG UACA ING1 GPX8 PABPC4L EBF1 PPIB SLC38A2 MYOF SLC12A2 KLHL15 DCLK3 ALDH9A1

9.32e-0679517918M39050
CoexpressionMURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL

CRISPLD2 KDELR2 COL6A1 ABCA1 HTRA1 WIPI1 COL12A1 HK1 UACA GPX8 EBF1 SLC38A2 MYOF AEBP1 G6PD SYNCRIP

1.91e-0568117916M39175
CoexpressionSERVITJA_ISLET_HNF1A_TARGETS_UP

COL6A1 MICAL1 HTRA1 NEBL FSTL5 ITGB2 AEBP1 ELAVL2

2.03e-051671798M2395
CoexpressionNUYTTEN_EZH2_TARGETS_DN

CAD MIS18BP1 NEBL RPS3 POLD1 DLGAP5 POLR2G GLIS3 ITGA6 PAK6 NFU1 KCNV1 UTP18 SLC30A5 SLC12A2 ZNF587 MDC1 GPCPD1 PDZD8 WIPI2

2.46e-05102317920M17122
CoexpressionLEE_BMP2_TARGETS_UP

CRISPLD2 COL6A1 COL7A1 ABCA1 HTRA1 WIPI1 HK1 LARP6 ACACB PPP1R9A PLXNB2 CRYL1 ALDH1A2 CCDC198 P2RX7 AEBP1 LIPG

2.71e-0578017917M2324
CoexpressionLI_CISPLATIN_RESISTANCE_UP

COL11A1 NEBL UACA HAPLN1

2.80e-05261794M4717
CoexpressionZHANG_UTERUS_C2_SECRETORY_STROMAL3_RAMP3_HIGH_CELL

CRISPLD2 KDELR2 COL6A1 HTRA1 WIPI1 GPX8 EBF1 PPIB ALDH1A2

2.97e-052291799MM16607
CoexpressionLEE_BMP2_TARGETS_UP

CRISPLD2 COL6A1 COL7A1 ABCA1 HTRA1 WIPI1 HK1 LARP6 ACACB PPP1R9A PLXNB2 CRYL1 ALDH1A2 CCDC198 P2RX7 AEBP1 LIPG

4.01e-0580517917MM1067
CoexpressionSERVITJA_ISLET_HNF1A_TARGETS_UP

COL6A1 MICAL1 HTRA1 NEBL FSTL5 ITGB2 AEBP1 ELAVL2

4.23e-051851798MM1072
CoexpressionZHANG_UTERUS_C1_PROLIFERATIVE_STROMAL1_MGP_HIGH_CELL

CRISPLD2 KDELR2 COL6A1 HTRA1 WIPI1 GPX8 EBF1 PPIB ALDH1A2 AEBP1

5.75e-0531017910MM16608
CoexpressionGSE21927_SPLEEN_VS_TUMOR_MONOCYTE_BALBC_DN

HNRNPF RYR1 AEBP1 DCLK3 HERC2 DNAH5 USP47 SYNCRIP

5.91e-051941798M7580
CoexpressionBMI1_DN.V1_UP

CRISPLD2 FLNB COL7A1 ABCA1 HAPLN1 KMT2A CTNS

7.02e-051471797M2782
CoexpressionGSE17721_POLYIC_VS_CPG_8H_BMDC_DN

KDELR2 POLR1A MAOA NCF4 ALDH1A2 UTP18 HERC2 SYNCRIP

7.07e-051991798M3947
CoexpressionGSE5589_UNSTIM_VS_180MIN_LPS_AND_IL10_STIM_MACROPHAGE_DN

CYLD CRISPLD2 CAD HK1 ING1 ZCCHC8 POLD1 KMT2A

7.07e-051991798M6605
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

ABCA1 AHI1 IKZF4 SLC12A2 TMEM131 SCIN WIPI2 AMIGO2

7.07e-051991798M9184
CoexpressionGSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_UP

CAD MAN2B1 NCF4 PAK6 RYR1 DRG1 PLCG2 G6PD

7.32e-052001798M5973
CoexpressionGSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_UP

PAPPA2 NIBAN1 PARK7 PPIB IKZF4 ALDH1A2 CCDC198 KIAA1217

7.32e-052001798M3220
CoexpressionGSE39864_WT_VS_GATA3_KO_TREG_DN

MAN2B1 PLXNB2 PPIB DRG1 SLC38A2 C4B ALDH9A1 SYNCRIP

7.32e-052001798M9063
CoexpressionCUI_DEVELOPING_HEART_COMPACT_VENTRICULAR_CARDIOMYOCYTE

COL6A1 NIBAN1 COL12A1 COL6A6 HAPLN1

8.33e-05651795M39309
CoexpressionGRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP

ALKBH4 PITPNM2 WIPI1 LRRC57 MAN2B1 CYP2F1 ACAD9 MYO1H RDH5 ITGA6 ALDH1L1 PLXNB2 OMP SLC12A2 RNPEP SLC37A2 PLA2G6 C4A C4B SCIN WIPI2

1.02e-04122617921MM979
CoexpressionZHANG_UTERUS_C0_SECRETORY_STROMAL3_NPPC_HIGH_CELL

CRISPLD2 KDELR2 COL6A1 HTRA1 WIPI1 GPX8 EBF1 PPIB HNRNPF ALDH1A2

1.14e-0433717910MM16606
CoexpressionGRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP

ALKBH4 PITPNM2 WIPI1 LRRC57 MAN2B1 CYP2F1 ACAD9 MYO1H RDH5 ITGA6 ALDH1L1 PLXNB2 OMP SLC12A2 RNPEP SLC37A2 PLA2G6 C4B SCIN WIPI2

1.24e-04115117920M1103
CoexpressionJECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP

COL6A1 HTRA1 C4A C4B CDH15

1.65e-04751795MM1143
CoexpressionWIERENGA_PML_INTERACTOME

CAD RPS3 HNRNPF DNAH5

1.92e-04421794M2219
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000

PAPPA2 CRISPLD2 COL6A1 COL11A1 HTRA1 COL12A1 MIS18BP1 POLR1A MYOM1 PABPC4L EBF1 SLC30A2 IKZF4 ALDH1A2 CCDC198 SLC12A2 AEBP1 LIPG DCLK3 COL14A1 WIPI2

3.58e-0679717821gudmap_developingGonad_P2_epididymis_1000
ToppCell10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL6A1 DPYS COL11A1 COL12A1 LARP6 RARG GPX8 HAPLN1 SCIN CDH15

8.31e-091951821030ed961151b8b1f6ce37f06c9a061519f01c2864
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PITPNM2 FLNB FAT4 COL12A1 UACA PPP1R9A ITGA6 KIAA1217 KMT2A PRKCH

1.06e-0820018210dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellfacs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 LARP6 GPX8 EBF1 AEBP1 COL14A1 C4B

5.59e-081791829f14440f6ce9b4fcdd4bcb2488b949f9a0e17bc23
ToppCellfacs-Pancreas-Endocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 LARP6 GPX8 EBF1 AEBP1 COL14A1 C4B

5.59e-0817918296f51a4580c06fc55cc764052c9b26f7c55660282
ToppCellfacs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 LARP6 GPX8 EBF1 AEBP1 COL14A1 C4B

5.59e-081791829a6ce1fa338d4905bd6afef00763ac83e916a0b37
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

CRISPLD2 COL6A1 HTRA1 COL12A1 GPX8 GLIS3 AEBP1 COL14A1 C4A

8.13e-081871829a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 COL6A1 HTRA1 GPX8 NTRK1 ALDH1A2 AEBP1 COL14A1 C4B

9.74e-0819118292b73fcd592d16cae8ded5e45c8fbf2d9adc8caad
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 FAT4 UACA ITGA6 SHANK3 SLC12A2 P2RX7 KIAA1217 PRKCH

1.02e-071921829c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 FAT4 UACA ITGA6 SHANK3 SLC12A2 P2RX7 KIAA1217 PRKCH

1.02e-07192182904f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 LARP6 GPX8 ALDH1A2 AEBP1 COL14A1 C4B

1.06e-07193182992048d2e9e43513e6185e09553be3ee47d7e5207
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 FLNB FAT4 UACA PPP1R9A ITGA6 SHANK3 KIAA1217 PRKCH

1.06e-071931829af5108260783e69a7d67896c5bf64f862525926d
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 FAT4 UACA PPP1R9A ITGA6 SHANK3 KIAA1217 GPCPD1 PRKCH

1.06e-071931829e1d546165dcc2392f540162206852c4717d7306f
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 LARP6 GPX8 ALDH1A2 AEBP1 COL14A1 C4B

1.06e-071931829ac088c8f27b5b1888610e461ff45870ca60da886
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 FLNB FAT4 UACA PPP1R9A ITGA6 SHANK3 KIAA1217 PRKCH

1.06e-071931829e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCelldroplet-Bladder-nan-3m|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 COL11A1 HTRA1 COL12A1 GPX8 ALDH1A2 AEBP1 COL14A1

1.06e-071931829e55f79bad6888b84b0ad5fccded498b170e3c6dc
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 FLNB FAT4 UACA PPP1R9A ITGA6 SHANK3 KIAA1217 PRKCH

1.06e-0719318296e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCelldroplet-Bladder-nan-3m-Epithelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 COL11A1 HTRA1 COL12A1 GPX8 ALDH1A2 AEBP1 COL14A1

1.11e-071941829b294056f9bdc243263cf36dce7b62564144b9de1
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 FLNB FAT4 UACA PPP1R9A ITGA6 SHANK3 KIAA1217 PRKCH

1.11e-0719418290b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-8|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

CRISPLD2 COL6A1 COL11A1 HTRA1 COL12A1 GPX8 AEBP1 DCLK3 CDH15

1.11e-07194182955b97095a7a17a312c616703d291738a0f806339
ToppCellNS-critical-d_07-13-Epithelial-unknown_epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COL7A1 AHI1 COL6A6 ING1 HECTD4 CALHM4 LIPG CDH15

1.23e-07141182833ad925ff7be3c682741a6328216a89f9d4033e9
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL6A1 COL11A1 COL12A1 LARP6 UACA GPX8 HAPLN1 SCIN CDH15

1.32e-0719818299d61483b0decac2fe90045b3474843360b2c49b3
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

CRISPLD2 COL6A1 ABCA1 COL6A6 POLD1 PPIB MYOF LIPG COL14A1

1.38e-071991829fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KDELR2 COL6A1 NIBAN1 COL12A1 RARG UACA COL6A6 GPX8 EBF1

1.38e-0719918299846d6a31635fde759d55674631c11ab9270a603
ToppCellControl_saline-Endothelial-Endothelial-Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

PITPNM2 FLNB FAT4 UACA PPP1R9A ITGA6 KIAA1217 GPCPD1 PRKCH

1.44e-0720018293b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PITPNM2 FLNB FAT4 COL12A1 UACA PPP1R9A ITGA6 KIAA1217 PRKCH

1.44e-072001829b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCellCOVID-19-Fibroblasts-Pathological_FB|COVID-19 / group, cell type (main and fine annotations)

CRISPLD2 KDELR2 COL6A1 HTRA1 GPX8 RPS3 PPIB AEBP1 COL14A1

1.44e-07200182973e01b7bc43320a991c67a4fd0c04708f893c7ea
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 COL6A1 HTRA1 COL12A1 LARP6 GPX8 EBF1 AEBP1 COL14A1

1.44e-072001829cfea2f9d85646c9b722150551ff2e8fc4f6cc98a
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 COL6A1 HTRA1 COL12A1 LARP6 GPX8 EBF1 AEBP1 COL14A1

1.44e-0720018296f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 COL6A1 HTRA1 COL12A1 LARP6 GPX8 EBF1 AEBP1 COL14A1

1.44e-0720018293a164e3971bcd62b148b813171c103adb81f972e
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 COL6A1 COL7A1 FAT4 ABCA1 GLIS3 HAPLN1 MYOF

4.92e-071691828c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 ADGRV1 RNF17 AEBP1 ELAVL2 C4B DNAH5 HYDIN

4.92e-07169182812bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A1 COL11A1 COL6A6 FREM3 ALDH1A2 AEBP1 COL14A1 C4B

6.14e-071741828a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL11A1 MIS18BP1 DLGAP5 ALDH1A2 AEBP1 COL14A1 C4B HAL

7.29e-071781828c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CRISPLD2 KDELR2 COL7A1 COL11A1 COL12A1 GPX8 ALDH1A2 AEBP1

8.62e-071821828812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 GPX8 NTRK1 AEBP1 COL14A1 C4B

8.99e-07183182863294d66e3ccf152ffe5d1237106764c14390b62
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 GPX8 NTRK1 AEBP1 COL14A1 C4B

8.99e-0718318287e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 COL6A6 GPX8 PLXNB2 AEBP1 C4B

9.75e-071851828eaa54b76743628c89b4310be57b87fa92b75fd37
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 COL6A6 GPX8 PLXNB2 AEBP1 C4B

9.75e-071851828ff38a15af3dec36d9993f06623591872b5d1da9a
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 COL6A6 GPX8 PLXNB2 AEBP1 C4B

9.75e-071851828f7f4c921d248c637351e2e882589b99ba7f04b66
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

DPYS COL11A1 COL12A1 LARP6 GPX8 HAPLN1 COL14A1 SCIN

1.06e-061871828f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

DPYS COL11A1 COL12A1 LARP6 GPX8 HAPLN1 COL14A1 SCIN

1.06e-06187182802e7246ef5ad41773d14426254e139b156d45c1d
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

DPYS COL11A1 COL12A1 LARP6 GPX8 HAPLN1 COL14A1 SCIN

1.06e-06187182808c73d125e0638c9e9878165bba2442c266c8a48
ToppCellCOPD-Epithelial-Mesothelial|Epithelial / Disease state, Lineage and Cell class

CRISPLD2 COL6A1 HTRA1 ALDH1A2 AEBP1 SYT4 C4A C4B

1.10e-061881828159d63ecc3653a7449fc6acefd6ef0464845260e
ToppCelldroplet-Pancreas-PANCREAS-30m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 COL12A1 GPX8 ALDH1A2 AEBP1 COL14A1

1.15e-0618918281821ae4a6e37ee4c6308071883f3f447a7c53c53
ToppCelldroplet-Pancreas-PANCREAS-30m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 COL12A1 GPX8 ALDH1A2 AEBP1 COL14A1

1.15e-0618918281e4d7e8dc98b3d70351e6a6c2aaf9ca01f141b8f
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 COL6A1 HTRA1 GPX8 NTRK1 ALDH1A2 AEBP1 COL14A1

1.15e-061891828f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 COL6A1 HTRA1 GPX8 NTRK1 ALDH1A2 AEBP1 COL14A1

1.15e-061891828378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCelldroplet-Pancreas-PANCREAS-30m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 COL12A1 GPX8 ALDH1A2 AEBP1 COL14A1

1.15e-0618918281dc415ed41815f4296dafd8cf7f3e014c44db1db
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 COL6A1 COL6A6 GLIS3 MYOF ALDH1A2 AEBP1 COL14A1

1.15e-0618918282a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCelldroplet-Lung-nan-18m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 GPX8 NTRK1 AEBP1 COL14A1 C4B

1.19e-06190182872c2b824acdc43139e6635785df3ed3feb58ec46
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 GPX8 NTRK1 AEBP1 COL14A1 C4B

1.19e-06190182897772e69e6f51ebffbb5433ca7b40f1048723220
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 COL6A1 FRMPD4 COL6A6 GLIS3 ALDH1A2 AEBP1 COL14A1

1.24e-061911828b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL6A1 DPYS COL11A1 COL12A1 LARP6 HAPLN1 SCIN CDH15

1.24e-061911828cc9a6a8fad17d6e1a08a68ab7512ae06b1249051
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL6A1 DPYS COL11A1 COL12A1 LARP6 HAPLN1 SCIN CDH15

1.24e-061911828c16b920ee69ea8536e020ac3475abf1ce972c1e6
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PAPPA2 CRISPLD2 COL6A1 HTRA1 COL12A1 GPX8 AEBP1 COL14A1

1.24e-0619118289bbafdf316c1fa3a9f1ee30d41dd7158b5c97279
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A1 COL7A1 COL11A1 COL12A1 COL6A6 ALDH1A2 AEBP1 COL14A1

1.24e-06191182875d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PAPPA2 COL6A1 COL11A1 COL12A1 RARG COL6A6 HAPLN1 COL14A1

1.24e-06191182844b1f62fdee03b157fe545f2ae6ff84f8929a8ac
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-3|TCGA-Ovary / Sample_Type by Project: Shred V9

CRISPLD2 COL6A1 COL11A1 COL6A6 ITGB2 HAPLN1 MYOF AEBP1

1.24e-06191182880d30d8eedb4c70b58440646325bc04c5700803e
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL6A1 HTRA1 LARP6 GPX8 NTRK1 PABPC4L AEBP1 COL14A1

1.24e-06191182824dc77ee8de01b42559f92721655f4281b114e17
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL6A1 HTRA1 GPX8 NTRK1 ALDH1A2 AEBP1 COL14A1 C4B

1.29e-061921828c3707243c5590d852c9f28429c96f50a1fa6b0dc
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 KDELR2 COL6A1 HTRA1 GPX8 AEBP1 COL14A1 C4B

1.29e-061921828fc940f91ff8e051631dbf25e6e8d73cf8337eccb
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 LARP6 GPX8 ALDH1A2 AEBP1 COL14A1

1.29e-061921828e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 COL6A1 COL6A6 GLIS3 MYOF ALDH1A2 AEBP1 COL14A1

1.29e-0619218283d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 COL6A1 COL6A6 GLIS3 MYOF ALDH1A2 AEBP1 COL14A1

1.29e-061921828ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL6A1 HTRA1 GPX8 NTRK1 ALDH1A2 AEBP1 COL14A1 C4B

1.29e-061921828f9fb24457999dc9e751a099d7f995543b9330ad4
ToppCellfacs-Trachea-24m-Mesenchymal|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 KDELR2 COL6A1 HTRA1 GPX8 AEBP1 COL14A1 C4B

1.29e-061921828e8af6ad1ae99cae13a82d0d8d7f38af9b777f0ba
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 COL6A1 FRMPD4 COL6A6 GLIS3 ALDH1A2 AEBP1 COL14A1

1.29e-0619218286f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 LARP6 GPX8 ALDH1A2 AEBP1 COL14A1

1.29e-0619218288937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 COL6A1 COL6A6 GLIS3 MYOF ALDH1A2 AEBP1 COL14A1

1.29e-061921828162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 LARP6 GPX8 ALDH1A2 AEBP1 COL14A1

1.29e-061921828ac1477433704573f95111eee6263b93668d2845e
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 KDELR2 COL6A1 HTRA1 GPX8 AEBP1 COL14A1 C4B

1.29e-0619218287a2e79490e4f7058bb76b46c45b5df9f729e3146
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

NIBAN1 CYP2F1 PPP1R9A GLIS3 ADGRV1 TMEM130 KIAA1217 DNAH5

1.34e-0619318282bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 KDELR2 COL6A1 HTRA1 GPX8 ALDH1A2 AEBP1 COL14A1

1.34e-061931828ff901d2f3d7a511639c1e3b76058896c0d8a8602
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 KDELR2 COL6A1 HTRA1 GPX8 ALDH1A2 AEBP1 COL14A1

1.34e-061931828735a72fac16397edde95e8eefa6f83caeb5ee5df
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 FAT4 UACA ITGA6 SHANK3 SLC12A2 KIAA1217 PRKCH

1.34e-06193182802f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 FAT4 UACA PPP1R9A ITGA6 SHANK3 KIAA1217 PRKCH

1.34e-061931828aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 FAT4 UACA PPP1R9A ITGA6 SHANK3 KIAA1217 PRKCH

1.34e-061931828c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 FAT4 UACA ITGA6 SHANK3 SLC12A2 KIAA1217 PRKCH

1.34e-0619318285122b1ffba42de190061be34ecdc6176f84e56a3
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 COL6A1 HTRA1 GPX8 NTRK1 AEBP1 COL14A1 C4B

1.34e-061931828fe9720185929ef849edd1b8eb4854306b392e5a2
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 COL6A1 HTRA1 GPX8 NTRK1 AEBP1 COL14A1 C4B

1.34e-061931828e27885a9e1a2a3e165c5366d4cfcda05c5454483
ToppCelldroplet-Heart-nan-3m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 COL6A6 GPX8 ALDH1A2 AEBP1 COL14A1

1.39e-061941828ce32e60bcea1b8baf496ce9050832bc8c77d8434
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CRISPLD2 COL6A1 COL7A1 COL11A1 COL12A1 UACA EBF1 AEBP1

1.39e-0619418282d66091097e106c7bee22e5281f50724700bdf8d
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRISPLD2 COL6A1 COL6A6 GLIS3 MYOF ALDH1A2 AEBP1 COL14A1

1.39e-0619418286e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL6A1 HTRA1 GPX8 NTRK1 ALDH1A2 AEBP1 COL14A1 C4B

1.39e-0619418285594f7437448cb4b37d2d100f44d30c4a367df26
ToppCelldroplet-Heart-nan-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 HTRA1 COL6A6 GPX8 ALDH1A2 AEBP1 COL14A1

1.39e-061941828a1dc157148885cc8d3685ac81a1f4e3562aeecc9
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 COL6A1 HTRA1 GPX8 NTRK1 AEBP1 COL14A1 C4B

1.39e-061941828c9e589fe7df6a9b377654581a2aebb607cbb03b9
ToppCellASK428-Mesenchymal|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CRISPLD2 COL6A1 LARP6 UACA GPX8 TMEM130 AEBP1 COL14A1

1.45e-0619518282b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCellASK428-Mesenchymal-Fibroblast|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CRISPLD2 COL6A1 LARP6 UACA GPX8 TMEM130 AEBP1 COL14A1

1.45e-061951828c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRISPLD2 COL6A1 FAT4 HTRA1 COL12A1 EBF1 AEBP1 COL14A1

1.45e-061951828f54bc4454270ff06e85596f98199372b50d0179f
ToppCelldroplet-Bladder-nan-3m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 COL6A1 COL11A1 HTRA1 COL12A1 ALDH1A2 AEBP1 COL14A1

1.50e-061961828f47e551ba484687ba6ce8c29a085106131364042
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRISPLD2 COL11A1 HTRA1 COL12A1 TMEM130 ALDH1A2 AEBP1 AMIGO2

1.50e-061961828545d2e4469924d333e3f655f559c899fa1260196
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CRISPLD2 COL6A1 ABCA1 COL6A6 MYOF ALDH1A2 COL14A1 DNAI7

1.56e-061971828fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CRISPLD2 COL6A1 COL12A1 LARP6 MAOA GPX8 AEBP1 COL14A1

1.56e-0619718283bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CRISPLD2 COL6A1 COL12A1 LARP6 MAOA GPX8 AEBP1 COL14A1

1.56e-06197182817344464fdcc5ba0c03959696b97c195f11e644c
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

CRISPLD2 COL6A1 COL12A1 NEBL UACA GLIS3 AEBP1 COL14A1

1.56e-061971828f1c8936986123a3151140c374fcd62d6705c530b
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 KDELR2 COL6A1 COL11A1 HTRA1 GPX8 AEBP1 COL14A1

1.56e-061971828036c4c9b3ae80e2dc21c24a84504d3da0541f945
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CRISPLD2 COL6A1 COL12A1 LARP6 MAOA GPX8 AEBP1 COL14A1

1.56e-0619718285b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCell10x5'v1-week_14-16-Mesenchymal_myocytic|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL6A1 COL11A1 COL12A1 LARP6 GPX8 HAPLN1 SCIN CDH15

1.62e-06198182855d2ed345101bec4b73f1242ba8c4d73073b7e88
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDELR2 COL6A1 COL11A1 HTRA1 COL12A1 GPX8 AEBP1 COL14A1

1.62e-0619818281b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCellFibroblasts-DKK3+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CRISPLD2 COL6A1 HTRA1 COL12A1 GPX8 MYOF AEBP1 COL14A1

1.62e-0619818284f4632f26a2043c5e4ab89031b4229b5dca1bd48
DrugMadecassol

COL6A1 COL7A1 COL11A1 COL12A1 COL14A1 PLA2G6

1.52e-06461786CID000108062
Drugglycerol

CAD HK1 POLR1A MAOA MYOM1 GPX8 NTRK1 POLR2G APCS NCF4 ADGRV1 ITGB7 EFTUD2 CRYL1 ALDH1A2 LIPG PLA2G6 PRKCH HAL PLD2 G6PD

2.25e-0682917821CID000000753
DrugAC1L1C2F

COL6A1 COL7A1 COL11A1 COL12A1 ITGA6 ALDH1A2 COL14A1 PLD2

2.48e-061101788CID000001711
DrugNitrarine dihydrochloride [20069-05-0]; Down 200; 10.6uM; PC3; HT_HG-U133A

ALKBH4 CYLD COL6A1 RARG NEBL ING1 UNC119 XYLB RPA4 TBL2

3.62e-06197178103683_DN
DrugDiclofenac sodium [15307-79-6]; Up 200; 12.6uM; PC3; HT_HG-U133A

RARG ING1 NTRK1 NCF4 IKZF4 LIPG COL14A1 CTNS SCIN TBL2

3.78e-06198178105861_UP
Drugcoenzyme 1

HK1 MAOA RDH5 NCF4 ALDH1L1 PAK6 NDUFB6 RYR1 CRYL1 ALDH1A2 P2RX7 XYLB HAL ALDH9A1 ART5 G6PD CYB5R1

4.74e-0659617817CID000000925
DrugGK-101

COL6A1 COL7A1 COL11A1 COL12A1 COL14A1

8.55e-06361785CID000161853
DrugClemizole hydrochloride [1163-36-6]; Down 200; 11uM; PC3; HT_HG-U133A

ABCA1 RARG ING1 HAPLN1 MYOF LIPG SERGEF PLCG2 WIPI2

2.20e-0519317893672_DN
DrugAGEPC

NCF4 ITGB2 PLA2G15 IKZF4 HAPLN1 PLA2G6 PRKCH C4A PLCG2 HAL PLD2 ART5

2.52e-0535617812CID000461545
DrugNitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A

CYLD COL11A1 MAOA RYR1 IKZF4 KSR1 CCDC198 SLC30A5 TBL2

2.59e-0519717896043_UP
DrugGlipizide [29094-61-9]; Down 200; 9uM; PC3; HT_HG-U133A

COL6A1 RARG ING1 SERGEF PRKCH XYLB SCIN PCM1 WIPI2

2.80e-0519917896645_DN
DrugUTP-NA

CAD HK1 POLR1A POLD1 POLR2G PMVK P2RX7 RBM6 PLA2G6 PLCG2 PLD2 ART5 ENTPD8

2.81e-0542017813CID000001181
DrugBenzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; HL60; HT_HG-U133A

ALKBH4 CYLD COL6A1 COL7A1 AHI1 ACACB NEBL ALDH1L1 CRYL1

2.92e-0520017892200_UP
Drugstrontium ranelate

COL6A1 COL7A1 COL11A1 COL12A1 SLC12A2 COL14A1

3.14e-05771786CID006918182
Diseasecutaneous melanoma, hair color

SLC24A5 ADGRV1 PLXNB2 SLC24A4 HERC2 CDH15

1.63e-06621716EFO_0000389, EFO_0003924
Diseaseobsolete_red blood cell distribution width

KDELR2 AHI1 WIPI1 HK1 CYP2C18 POLR1A ZCCHC8 NTRK1 HECTD4 FREM3 KSR1 SLC12A2 LIPG KIAA1217 NT5C2 RBM6 ELAVL2 PLA2G6 G6PD TBL2 CDH15 USP47

1.18e-05134717122EFO_0005192
Diseasebody weight

PAPPA2 COL11A1 POLR1A EPHA6 PARK7 HECTD4 EBF1 ADGRV1 SIM1 PAK6 SPATA31C1 SLC38A2 ALDH1A2 UTP18 SLC12A2 SLC24A4 KIAA1217 ELAVL2 SYT4 PLA2G6 PCM1

1.42e-05126117121EFO_0004338
Diseaseresponse to carboplatin, response to antineoplastic agent

FLNB CRYL1 PLCG2

2.23e-05101713GO_0097327, GO_0097328
Diseasefree cholesterol in small HDL measurement

ABCA1 ALDH1A2 LIPG NYNRIN

4.96e-05351714EFO_0022270
Diseaselipoprotein measurement, phospholipid measurement

ABCA1 MYO1H ALDH1A2 LIPG NYNRIN

1.39e-04851715EFO_0004639, EFO_0004732
Diseasephosphoglycerides measurement

ABCA1 MYO1H ALDH1A2 LIPG

1.74e-04481714EFO_0022291
Diseasemetabolic syndrome

ABCA1 HECTD4 ALDH1A2 LIPG NT5C2 RBM6 KMT2A

1.74e-042001717EFO_0000195
Diseasenevus count, cutaneous melanoma

ADGRV1 PLXNB2 PLA2G6 HERC2 CDH15

1.92e-04911715EFO_0000389, EFO_0004632
DiseaseUllrich congenital muscular dystrophy

COL6A1 COL12A1

1.99e-0441712cv:C4551860
DiseaseBethlem myopathy

COL6A1 COL12A1

1.99e-0441712cv:C1834674
DiseaseBETHLEM MYOPATHY 1

COL6A1 COL12A1

1.99e-0441712C1834674
DiseaseUllrich congenital muscular dystrophy 1

COL6A1 COL12A1

1.99e-0441712C0410179
Diseasechronic obstructive pulmonary disease, interleukin-8 measurement

P2RX7 HYDIN

1.99e-0441712EFO_0000341, EFO_0004811
DiseaseBethlem myopathy (is_implicated_in)

COL6A1 COL12A1

1.99e-0441712DOID:0050663 (is_implicated_in)
DiseaseUllrich congenital muscular dystrophy (is_implicated_in)

COL6A1 COL12A1

1.99e-0441712DOID:0050558 (is_implicated_in)
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

ABCA1 WIPI1 ACACB MYO1H ALDH1A2 LIPG PLA2G6 CDH15

2.19e-042761718EFO_0004612, EFO_0020943
Diseasephospholipids in medium HDL measurement

ABCA1 MYO1H ALDH1A2 LIPG

2.95e-04551714EFO_0022295
DiseasePsychotic Disorders

MAOA NTRK1 SLC12A2 TPH2 PLA2G6

3.12e-041011715C0033975
Diseaseosteoarthritis

PITPNM2 KDELR2 COL11A1 FSTL5 GLIS3 ALDH1A2 RBM6

3.28e-042221717MONDO_0005178
Diseasearecaidine measurement

PYROXD2 MYOF

3.30e-0451712EFO_0801112
Diseasecholine measurement, phosphatidylcholine measurement

ALDH1A2 LIPG

3.30e-0451712EFO_0010116, EFO_0010226
Diseasecongenital nonspherocytic hemolytic anemia (is_implicated_in)

HK1 G6PD

3.30e-0451712DOID:2861 (is_implicated_in)
Diseaseatopy

ADGRV1 PAK6

3.30e-0451712EFO_0002686
Diseasetotal lipids in medium HDL measurement

ABCA1 MYO1H ALDH1A2 LIPG

3.62e-04581714EFO_0022310
Diseasefree cholesterol in medium HDL measurement

ABCA1 MYO1H ALDH1A2 LIPG

3.62e-04581714EFO_0022267
Diseasefree cholesterol in HDL measurement

ABCA1 MYO1H ALDH1A2 LIPG

4.39e-04611714EFO_0022264
Diseasephospholipids in HDL measurement

ABCA1 MYO1H ALDH1A2 LIPG

4.39e-04611714EFO_0022293
Diseaseapolipoprotein A 1 measurement

PAPPA2 PITPNM2 COL7A1 ABCA1 ACACB MYO1H EBF1 PKD1L3 ALDH1A2 LIPG RBM6 KMT2A SYT4 PLA2G6

4.46e-0484817114EFO_0004614
Diseasemetabolite measurement

SLC24A5 DPYS COL11A1 PYROXD2 ALDH1L1 SLC38A2 MYOF ALDH1A2 RNPEP ALDH9A1 G6PD

4.49e-0456017111EFO_0004725
DiseaseAlzheimer disease, high density lipoprotein cholesterol measurement

ABCA1 ALDH1A2 LIPG

4.51e-04261713EFO_0004612, MONDO_0004975
Diseasepanic disorder (is_implicated_in)

MAOA TPH2

4.93e-0461712DOID:594 (is_implicated_in)
Diseasetotal lipids in HDL measurement

ABCA1 MYO1H ALDH1A2 LIPG

4.97e-04631714EFO_0022307
Diseasetotal lipids in very large HDL measurement

ABCA1 WIPI1 ALDH1A2 LIPG

5.93e-04661714EFO_0022312
Diseasephospholipid measurement, high density lipoprotein cholesterol measurement

COL7A1 ABCA1 WIPI1 CYP2C18 MYO1H ALDH1A2 LIPG NYNRIN

5.97e-043211718EFO_0004612, EFO_0004639
Diseasecerebral infarction (is_implicated_in)

PARK7 LIPG PRKCH

6.25e-04291713DOID:3526 (is_implicated_in)
Diseaseomega-3 polyunsaturated fatty acid measurement

ABCA1 COL11A1 AHI1 ALDH1A2 LIPG

6.36e-041181715EFO_0010119
DiseaseSchizophrenia

ABCA1 AHI1 HK1 MAOA NTRK1 SHANK3 SLC38A2 ALDH1A2 SLC12A2 TPH2 KMT2A ELAVL2 PLA2G6 PCM1

6.63e-0488317114C0036341
DiseaseAngle Closure Glaucoma

COL11A1 GLIS3

6.88e-0471712C0017605
Diseasecutaneous melanoma

ADGRV1 PLXNB2 PLA2G6 HAL HERC2

7.13e-041211715EFO_0000389
Diseasephospholipids in large HDL measurement

ABCA1 MYO1H ALDH1A2 LIPG

8.68e-04731714EFO_0022190
Diseasedocosahexaenoic acid measurement

ABCA1 COL11A1 ALDH1A2 LIPG TBL2

8.87e-041271715EFO_0007761
Diseasetotal lipids in large HDL

ABCA1 MYO1H ALDH1A2 LIPG

9.14e-04741714EFO_0022189
Diseasepantothenate measurement

ABCA1 CAD

9.14e-0481712EFO_0021034
Diseasememory impairment

FAT4 SHANK3

9.14e-0481712EFO_0001072
DiseaseVaricose veins

ITGA6 EBF1 ADGRV1 SLC12A2 COG6 KMT2A

9.43e-041931716HP_0002619
Diseasetriglyceride measurement, response to diuretic

COL11A1 RAX KIAA1217

1.00e-03341713EFO_0004530, GO_0036270
Diseasefree cholesterol in large HDL measurement

ABCA1 MYO1H ALDH1A2 LIPG

1.17e-03791714EFO_0022157
DiseaseDepression, Bipolar

MAOA NTRK1 FSTL5 TPH2

1.17e-03791714C0005587
Diseasereticulocyte count

PITPNM2 FLNB ABCA1 WIPI1 HK1 ZCCHC8 HECTD4 EBF1 PLXNB2 NT5C2 PLA2G6 C4B TMEM131 PLCG2 WIPI2

1.17e-03104517115EFO_0007986
Diseaselow tension glaucoma

FLNB ABCA1

1.17e-0391712EFO_1001022
Diseasecholesterol in small HDL measurement

ALDH1A2 LIPG TBL2

1.19e-03361713EFO_0022226
DiseaseIntellectual Disability

AHI1 HK1 FRMPD4 ZCCHC8 SHANK3 FCSK KLHL15 NT5C2 RAB39B

1.25e-034471719C3714756
Diseasereticulocyte measurement

PITPNM2 FLNB ABCA1 WIPI1 HK1 ZCCHC8 HECTD4 EBF1 PLXNB2 SLC12A2 NT5C2 RBM6 TMEM131 PLCG2 WIPI2

1.26e-03105317115EFO_0010700
Diseasehair colour measurement, eye colour measurement, skin pigmentation measurement

SLC24A5 HERC2

1.46e-03101712EFO_0007009, EFO_0007822, EFO_0009764
Diseasefasting blood glucose measurement

KDELR2 WIPI1 GLIS3 PAK6 SLC24A4 TPH2 PLA2G6

1.48e-032871717EFO_0004465
DiseaseDisorder of eye

SLC24A5 COL11A1 AHI1 RDH5 ADGRV1 UNC119

1.53e-032121716C0015397
Diseaseobesity (implicated_via_orthology)

FAT4 HK1 SIM1 PLXNB2 ALDH1A2 NT5C2

1.64e-032151716DOID:9970 (implicated_via_orthology)
Diseaseserum alanine aminotransferase measurement

COL12A1 ZCCHC8 HECTD4 ALDH1L1 PLXNB2 FCSK ALDH1A2 P2RX7 NYNRIN SEPTIN14 RBM6 PLA2G6 TBL2

1.73e-0386917113EFO_0004735
Diseaseprimary angle closure glaucoma

COL11A1 GLIS3

1.77e-03111712EFO_1001506
Diseasepigmentation disease (is_implicated_in)

SLC24A4 HERC2

1.77e-03111712DOID:10123 (is_implicated_in)
Diseasediabetic nephropathy, type 2 diabetes mellitus

FSTL5 KCNV1

1.77e-03111712EFO_0000401, MONDO_0005148
DiseaseEnzymopathy

HK1 G6PD

1.77e-03111712C0520572
Diseaselipid measurement, lipoprotein measurement

ABCA1 ALDH1A2 LIPG NYNRIN

1.89e-03901714EFO_0004529, EFO_0004732
Diseaseeye color

SLC24A5 HK1 SLC24A4 HERC2

1.89e-03901714EFO_0003949
Diseaseglaucoma

ABCA1 COL11A1 KMT2A HERC2 ALDH9A1

2.08e-031541715MONDO_0005041
Diseasehair colour measurement, hair morphology measurement

SLC24A4 HERC2

2.12e-03121712EFO_0007821, EFO_0007822
DiseaseCongenital muscular dystrophy

COL6A1 RYR1

2.12e-03121712cv:C0699743
Diseasephospholipids:total lipids ratio, high density lipoprotein cholesterol measurement

ABCA1 WIPI1 MYO1H PKD1L3 ALDH1A2 LIPG CDH15

2.16e-033071717EFO_0004612, EFO_0020946
Diseasecentral corneal thickness

COL6A1 COL12A1 GLIS3 MYOF KMT2A XYLB HERC2

2.24e-033091717EFO_0005213
Diseasesaturated fatty acids measurement

ABCA1 ALDH1A2 LIPG

2.27e-03451713EFO_0022304
Diseasehair color

PARK7 HECTD4 ADGRV1 PLXNB2 SLC38A2 SLC24A4 HERC2

2.33e-033111717EFO_0003924
Diseasefree cholesterol measurement, high density lipoprotein cholesterol measurement

ABCA1 WIPI1 CYP2C18 MYO1H ALDH1A2 LIPG NYNRIN

2.50e-033151717EFO_0004612, EFO_0008591
Diseasetotal cholesterol measurement, high density lipoprotein cholesterol measurement

ABCA1 WIPI1 CYP2C18 MYO1H ALDH1A2 LIPG NYNRIN

2.50e-033151717EFO_0004574, EFO_0004612
Diseasealcohol consumption measurement, high density lipoprotein cholesterol measurement

ABCA1 EBF1 ALDH1A2 RBM6 PLA2G6

2.59e-031621715EFO_0004612, EFO_0007878
Diseasetriglyceride measurement, alcohol drinking

ABCA1 EBF1 ALDH1A2 PLA2G6

2.67e-03991714EFO_0004329, EFO_0004530
Diseasetotal lipids in lipoprotein particles measurement

ABCA1 ALDH1A2 LIPG

2.73e-03481713EFO_0022309
Diseasetriglyceride measurement, alcohol consumption measurement

ABCA1 EBF1 ALDH1A2 PLA2G6

2.87e-031011714EFO_0004530, EFO_0007878
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

ABCA1 ACACB MYO1H ALDH1A2 NYNRIN

2.88e-031661715EFO_0004530, EFO_0004611
Diseasereading and spelling ability

FSTL5 SLC24A4 ELAVL2 SYT4 PRKCH

2.88e-031661715EFO_0005301
DiseaseHepatic fibrosis

CYP2F1 SLC24A4 CDH15

2.90e-03491713HP_0001395
Diseaseglucose-dependent insulinotropic peptide measurement, glucose tolerance test

PAPPA2 ADAM30

2.90e-03141712EFO_0004307, EFO_0008464
Diseaseanemia (is_implicated_in)

HK1 G6PD

2.90e-03141712DOID:2355 (is_implicated_in)
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

ABCA1 SIM1 ALDH1A2 NYNRIN

2.98e-031021714EFO_0004329, EFO_0004611
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

ABCA1 ACACB ALDH1A2 LIPG PLA2G6 CDH15

3.02e-032431716EFO_0004612, EFO_0020944
Diseasealcohol drinking, high density lipoprotein cholesterol measurement

ABCA1 EBF1 ALDH1A2 RBM6 PLA2G6

3.03e-031681715EFO_0004329, EFO_0004612
Diseasenon-high density lipoprotein cholesterol measurement

ABCA1 HK1 MYO1H GLIS3 SIM1 ALDH1A2 LIPG NYNRIN GPCPD1 PLA2G6 HYDIN

3.07e-0371317111EFO_0005689
Diseasepulse pressure measurement

PAPPA2 COL6A1 FLNB COL11A1 NEBL ING1 EBF1 SLC35E2B PKD1L3 PLXNB2 FCSK SLC12A2 KIAA1217 NT5C2 SYT4 HYDIN PCM1

3.08e-03139217117EFO_0005763
Diseaselipid measurement, high density lipoprotein cholesterol measurement

ABCA1 WIPI1 CYP2C18 MYO1H ALDH1A2 LIPG NYNRIN

3.23e-033301717EFO_0004529, EFO_0004612
Diseasefree cholesterol to total lipids in small HDL percentage

ABCA1 WIPI1 ALDH1A2

3.25e-03511713EFO_0022285
Diseaselipoprotein measurement

ABCA1 MYO1H ALDH1A2 LIPG

3.30e-031051714EFO_0004732
Diseasetotal lipids in LDL measurement

ABCA1 ALDH1A2 NYNRIN

3.43e-03521713EFO_0022308
Diseasetotal phospholipids in lipoprotein particles measurement

ABCA1 ALDH1A2 LIPG

3.62e-03531713EFO_0022315
Diseasetriglycerides in HDL measurement

ABCA1 ALDH1A2 LIPG

3.62e-03531713EFO_0022317
Diseasehepatocellular carcinoma (biomarker_via_orthology)

ABCA1 CAD PPP1R9A G6PD

3.66e-031081714DOID:684 (biomarker_via_orthology)
Diseasecup-to-disc ratio measurement

FLNB FAT4 COL11A1 COL12A1 NEBL MYO1H KMT2A PLA2G6

3.73e-034301718EFO_0006939
Diseasetreatment-resistant hypertension

COL11A1 POLR1A PABPC4L TPH2

3.78e-031091714EFO_1002006
Disease4-acetamidobutanoate measurement

PLXNB2 ALDH1A2

3.80e-03161712EFO_0021003
Diseasegliosarcoma

CYP2C18 SEPTIN14

3.80e-03161712C0206726
Diseaseautism spectrum disorder (is_implicated_in)

AHI1 MAOA

3.80e-03161712DOID:0060041 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
KTEGFCGLPSFSREV

ALKBH4

121

Q9NXW9
SGTEKAFEPATGRVI

ALDH9A1

26

P49189
VIEEFLATGEKLFGP

RNPEP

266

Q9H4A4
LKVVARGSFEFPVGD

C4B

911

P0C0L5
RGSFEFPVGDAVSKV

C4B

916

P0C0L5
ILVDARKPLFFGEGT

NT5C2

286

P49902
TGKVVGVFRPETVAS

AAMP

291

Q13685
FGFTQTGIISIERKP

AHI1

1031

Q8N157
GLGRKGFFIEPTVFS

ALDH1A2

391

O94788
TEFGTEVEPEFGTKV

AEBP1

1091

Q8IUX7
APKGTIVGEVFASDR

FAT4

3311

Q6V0I7
AFVGGSKVVILDEPT

ABCA1

1046

O95477
KITAFIVERDFGGVT

ACAD9

241

Q9H845
GRTIISPAISGKDFV

ADGRV1

5546

Q8WXG9
GKDFVITEGTLVFEP

ADGRV1

5556

Q8WXG9
GKVRLFPSEAVIAEG

AMIGO2

481

Q86SJ2
DVVVTDFRFGTIPVK

AADACL3

86

Q5VUY0
FLSPFSVPEARGDKV

SLC24A4

411

Q8NFF2
GVDFFSRLLEIEPGK

RAB39A

46

Q14964
VGVDFFSRLVEIEPG

RAB39B

41

Q96DA2
VDVRVPGFGKTFSLE

PLA2G15

111

Q8NCC3
IVEFAKRLPGFTGLS

RARG

241

P13631
AFRGFLIPKGTDVIT

CYP2F1

376

P24903
ACVILTFKEPFGTEG

G6PD

231

P11413
FLVTFGEGVEPANLK

OMP

141

P47874
TGVFQLKDRGLTEFP

LRRC57

16

Q8N9N7
SPAEFVTRFGGDRVI

ACACB

246

O00763
PVGRIFFAGTETATK

MAOA

426

P21397
VFFDITVDGKPLGRI

PPIAL4C

6

A0A0B4J2A2
KDETPFGVSVAVGLA

NTRK1

411

P04629
RVHTSFDPKEGKFVG

PAK6

21

Q9NQU5
SGVRKEFPITEAVGS

MIS18BP1

846

Q6P0N0
TAPKVLFTGVVDARG

MDC1

1891

Q14676
KTGDARIGFVGFPSV

DRG1

61

Q9Y295
IEGVKSVFFGPDFIT

NFU1

106

Q9UMS0
DEFGEGTVTRITPKG

HERC2

2226

O95714
ESGSKPFTRQEVIGF

SLC66A1

171

Q6ZP29
LLPTDIKFGIVFDAG

ENTPD8

36

Q5MY95
FKERVGYREGPTVET

KIAA1143

21

Q96AT1
FLPDGRSVVDTVGGK

LONRF1

631

Q17RB8
GVFSVTAGDGKFIPR

DPYS

451

Q14117
GGDLFDAIIESVKFP

DCLK3

436

Q9C098
VGRSPVFLFEDHTGK

COL11A1

131

P12107
GTEIFVGKIPRDLFE

SYNCRIP

161

O60506
EKPGSSTAARIFGVI

KCNV1

201

Q6PIU1
GDIRPDTTTGKIVAF

KCNV1

396

Q6PIU1
VDTSRIKVFGPGIEG

FLNB

1226

O75369
IPFAVRKGEITGEVH

FLNB

1751

O75369
EGEVEKPFIKTGFSV

PCM1

1216

Q15154
ETPFTGGVEVDVFGK

PLXNB2

866

O15031
SSKVVPRFERFGLGV

KSR1

901

Q8IVT5
RGPGTSFEFALAIVE

PARK7

156

Q99497
RDVFLGETVPFIKTI

PDZD8

146

Q8NEN9
KSRIFPGDTILETGE

NDUFB6

101

O95139
GLVDITRNGKVPFFV

CRISPLD2

346

Q9H0B8
TVRGATGIFPLSFVK

NCF4

211

Q15080
FVKGTVGRITGLDPA

LIPG

181

Q9Y5X9
FGTFGVISSVRILKP

LARP6

221

Q9BRS8
VFIETGTARGVVGFK

LYPD4

66

Q6UWN0
FDVLISAAGGKFVPE

MICAL1

211

Q8TDZ2
GIVSKDEITFVSGAP

ITGA6

306

P23229
GKDGTFLVRESETFP

PLCG2

556

P16885
LPKGTEFVVFSIDGS

PITPNM2

1101

Q9BZ72
GPIVSFGFTTEAEKR

HECTD4

2011

Q9Y4D8
TFVRSIPDGSEKGDF

HK1

66

P19367
LGFIFLESEGRPTKE

FSTL5

11

Q8N475
IGFGSFVDKTVLPFV

ITGB7

191

P26010
VFFDITVDGKPLGRI

PPIAL4H

6

A0A075B767
IGFGSFVDKTVLPFV

ITGB2

166

P05107
RAIFIFLTTDGLVPG

PAPPA2

1276

Q9BXP8
VFFDITVDGKPLGRI

PPIAL4A

6

Q9Y536
IFFDITVDGKPLGRI

PPIAL4G

6

P0DN37
KVFGIRFDILVFGTG

P2RX7

311

Q99572
RGTREGPITEDFFKA

COG6

171

Q9Y2V7
DGRVPLVSGVVFFSV

FCSK

216

Q8N0W3
ISFFGALRIPGVVEF

SLC37A2

286

Q8TED4
PEKLSFRGEVQGVVS

ADAM30

46

Q9UKF2
DELGVFSLKGRPTTA

HYDIN

3526

Q4G0P3
ITTGFGKFARTVIPI

HAL

166

P42357
KREVPVASGSGFIVS

HTRA1

196

Q92743
VAFEIRGTLLPGEVF

GPCPD1

6

Q9NPB8
SVPRSEFAVGVIGKF

KLHL15

366

Q96M94
VVSVGIKDVFDFIPG

COL6A1

751

P12109
FTESAGARVGFPKVA

COL12A1

231

Q99715
GARVGFPKVAIIITD

COL12A1

236

Q99715
TVTFEGPEIRKIFYG

COL14A1

1341

Q05707
VLGFGFVAGSEKPVV

FRMPD4

86

Q14CM0
GISVPKGIRNIFEFT

C3orf20

36

Q8ND61
GLFKTERLEEFPGST

GLIS3

271

Q8NEA6
LFGFIPGSEDVKHIR

CALHM4

251

Q5JW98
KIVFDAGFFRVESPV

DLGAP5

606

Q15398
AGFFRVESPVKLFSG

DLGAP5

611

Q15398
KERLVTFSLDTFGPV

DNAI7

476

Q6TDU7
PVEIERTAFVGFVEK

EBF1

81

Q9UH73
FGPFGAVTNVKVIRD

ELAVL2

296

Q12926
SEGVFVVKDPNGRTV

MAN2B1

531

O00754
IKGEVVPENGFEVFR

KMT2A

1981

Q03164
EVRSFLEGLVLPFSG

COL7A1

56

Q02388
GEEFSGRGSFPVAEK

CYP2C18

91

P33260
FGPIPEFSRATAEKV

CRYL1

266

Q9Y2S2
GDPTKFGLGVFSIVF

CTNS

331

O60931
PLLAERTVSGIFFGV

CYLD

151

Q9NQC7
KILGSEGEPAFRFLV

GPX8

141

Q8TED1
KEVETPSAGRVDFAF

CCDC198

21

Q9NVL8
IFGGVDVPAKFITIL

SLC22A8

361

Q8TCC7
GGSVEFQFVPVLKLV

RYR1

1831

P21817
GVDEEPRGVFSIDKF

CDH15

86

P55291
SVPVLRAFGVTDEGF

POLD1

121

P28340
DTFRVEFLVVPVGGL

KDELR2

91

P33947
VLRVVGESGEPVKAF

IKZF4

516

Q9H2S9
LKVVARGSFEFPVGD

C4A

911

P0C0L4
RGSFEFPVGDAVSKV

C4A

916

P0C0L4
EFPLGTFIGEKEISF

COL6A6

1051

A6NMZ7
LPSEASVDKIFGVIG

DNAH5

2731

Q8TE73
TPFKVLTGGESRLTE

NYNRIN

1756

Q9P2P1
VTEDLLFRKFSTVGP

PABPC4L

21

P0CB38
SPTEAAVRFVGFPDK

HAPLN1

326

P10915
EGVVTKRSFPAIGVE

EPHA6

696

Q9UF33
DNVGPKVFVGESFIV

FREM3

1066

P0C091
RGLPFGCTKEEIVQF

HNRNPF

116

P52597
FDEIPTVVGIFSAFG

SYT4

11

Q9H2B2
EKIVRSFEVSPDGSF

UTP18

341

Q9Y5J1
TIERPAFGIQKGEFE

RBM6

321

P78332
FISFIKSPEGGEELV

RGSL1

91

A5PLK6
RFEKVFESAVDPGAV

SPATA6L

56

Q8N4H0
LFFTAKEPSRVTGLE

SERGEF

196

Q9UGK8
VTGRFLTGIKPPEFF

POLR1A

951

O95602
GLLPFAVVGSTDEVK

SEPTIN14

241

Q6ZU15
NKTGRFVIEEIPGEF

SCIN

621

Q9Y6U3
SPATFGRGFIAVAVI

ING1

131

Q9UK53
DPQKTVFERGGLDVF

PKD1L3

781

Q7Z443
DVGRVIFGLFGKTVP

PPIB

56

P23284
QTLDGFIFVVAPDGK

SIM1

86

P81133
VGEAVATLKGEFPTL

KIAA1217

761

Q5T5P2
AVVQKRFGFPEGSVE

RPS3

71

P23396
SEKGTVIRVFSIPEG

WIPI2

221

Q9Y4P8
DFGETPTFLASKIGR

PLA2G6

381

O60733
FPGKVLGATSEESER

SPATA31C1

541

P0DKV0
KAGGVVPAFLVELVS

SLC38A8

51

A6NNN8
DSLKVGDVVEFRGPS

CYB5R1

136

Q9UHQ9
VPFSKDTVSDVGVGL

SANBR

496

Q6NSI8
ADPGFFCRKIVEGIS

PMVK

86

Q15126
FGIRVSIVEPGFFRT

RDH5

196

Q92781
FTKDDGILGTFPAER

RAX

41

Q9Y2V3
EGAVPTIFESFSKLR

THAP7

86

Q9BT49
PDVRKIGFTGSTEVG

ALDH1L1

641

O75891
GDDGTIFVVPKLSEF

RNF17

1191

Q9BXT8
EKGPLTFRDVVIEFS

ZNF738

31

Q8NE65
AEEVEERFGRFKPGV

ZCCHC8

276

Q6NZY4
RQVGATVEFTVGDKP

UNC119

141

Q13432
SSTVFDPVFKVRGII

RPA4

56

Q13156
GPVSSGFSEVRVLFE

NIBAN1

356

Q9BZQ8
VFRPFKGEVVDAVVT

POLR2G

76

P62487
TDLSGKVFVFPRESV

APCS

21

P02743
GFGFVLRGAKAETPI

SHANK3

581

Q9BYB0
GAAVTEEIIPGFKFS

PYROXD2

71

Q8N2H3
APGFKDSVVGRDILT

PYROXD2

491

Q8N2H3
VPTIRDIFGFIGASA

SLC38A2

431

Q96QD8
VFREFGKDVLPSSGL

ZNF587

171

Q96SQ5
EAVLLRGTTVAPGFK

ZNF75CP

146

Q92670
IGDFVIGTFIPLESK

SLC12A2

446

P55011
RKILPGGNTSFDVVF

TMEM131

161

Q92545
SPQLKEFFRGGEVTR

SNX15

116

Q9NRS6
EFFRGGEVTRPLEVS

SNX15

121

Q9NRS6
LAGGTDVPFSEVVKL

XYLB

481

O75191
VFREFGKDVLPSSGL

ZNF417

171

Q8TAU3
EFAKGRGTFPCDISV

USP47

1271

Q96K76
PELVTAFLGVFITKG

SLC24A5

121

Q71RS6
FFTDVPVIGRSGKSF

SLC35E2B

276

P0CK96
FLKERSGFTVRPVAG

TPH2

266

Q8IWU9
SGVVGVKVPQFSFSR

CAD

1256

P27708
PGKLDVEGRSVFHVV

UACA

61

Q9BZF9
APFKVGALSTEVLGR

VWA5B2

731

Q8N398
GPAKTRGAAFFIIAV

SLC30A5

146

Q8TAD4
ARGFVVLPITEFLVG

TMEM130

121

Q8N3G9
EKGTVIRVFSVPDGQ

WIPI1

206

Q5MNZ9
FFVPGDRQVVIGTKT

WDR3

461

Q9UNX4
LFTEQERGVGIKSTP

EFTUD2

171

Q15029
FDPGFEVQVGKRSTE

PLD2

261

O14939
GTERVDPGFEGVTLK

ZGLP1

136

P0C6A0
GRFVASCGFTPDVKV

TBL2

241

Q9Y4P3
GIFVPFLRAGSEVLT

TYSND1

51

Q2T9J0
GTPKGVDFTAVRDLL

SLC30A2

231

Q9BRI3
PEGKVFVVITLTGSF

PRKCH

126

P24723
FVDGEGKPRLIVSSS

LGI3

381

Q8N145
EVVFRGVGSLRFEPK

ART5

156

Q96L15
FISPGKEGTIVFDTG

MYO1H

996

Q8N1T3
VGKDEFLGRSIFSPV

MYOF

1221

Q9NZM1
GRTPVTGYFVDLKEA

MYOM1

1066

P52179
FVIGREKPGQVSEVA

PPP1R9A

586

Q9ULJ8
HEDFEKTKGRGFTPV

NEBL

786

O76041