Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	SMARCA5 CHD4 INO80 CHD5 RAD54B SMARCA1 HELLS	1.26e-08	37	155	7	GO:0140658
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	SMARCA5 CHD4 INO80 CHD5 RAD54B SMARCA1 HELLS	6.08e-05	127	155	7	GO:0008094
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	SMARCA5 CHD4 INO80 TEP1 CHD5 RAD54B SMARCA1 NME1 HELLS	2.14e-04	262	155	9	GO:0140097
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine phosphatase activity	PTPRU PTPRG PTPRH	2.88e-04	17	155	3	GO:0005001
GeneOntologyMolecularFunction	transmembrane receptor protein phosphatase activity	PTPRU PTPRG PTPRH	2.88e-04	17	155	3	GO:0019198
GeneOntologyCellularComponent	presynaptic membrane	GABRB2 CACNA1C CACNA1D LRFN3 L1CAM RGS9 CNTN6 NRXN2 SEPTIN7 CACNA2D3	4.81e-05	277	157	10	GO:0042734
GeneOntologyCellularComponent	apical part of cell	CACNA1D PDE4D CDHR2 SPTBN2 ABCC5 PTCH1 NEDD1 SLC3A1 PROM1 PTPRH PKHD1 SEPTIN7 CDH1 ABCG8	1.56e-04	592	157	14	GO:0045177
GeneOntologyCellularComponent	Cul3-RING ubiquitin ligase complex	KLHL2 KLHL20 KLHL3 KLHL42	2.05e-04	39	157	4	GO:0031463
GeneOntologyCellularComponent	presynaptic active zone membrane	GABRB2 CACNA1D LRFN3 NRXN2 CACNA2D3	3.04e-04	78	157	5	GO:0048787
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNA1C CACNA1D PDE4D CACNA2D3	3.91e-04	46	157	4	GO:0005891
GeneOntologyCellularComponent	presynaptic active zone	GABRB2 CACNA1D LRFN3 DAO NRXN2 CACNA2D3	6.94e-04	141	157	6	GO:0048786
GeneOntologyCellularComponent	SWI/SNF superfamily-type complex	SMARCA5 CHD4 INO80 CHD5 SMARCA1	7.91e-04	96	157	5	GO:0070603
GeneOntologyCellularComponent	postsynaptic cytoskeleton	MYH10 SPTBN2 SEPTIN7	9.52e-04	26	157	3	GO:0099571
GeneOntologyCellularComponent	NURF complex	SMARCA5 SMARCA1	1.15e-03	7	157	2	GO:0016589
GeneOntologyCellularComponent	apical plasma membrane	CACNA1D PDE4D CDHR2 SPTBN2 ABCC5 SLC3A1 PROM1 PTPRH PKHD1 SEPTIN7 ABCG8	1.16e-03	487	157	11	GO:0016324
Domain	BACK	KLHL2 KLHL10 BTBD2 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5 KLHL42	1.99e-09	61	157	9	IPR011705
Domain	BACK	KLHL2 KLHL10 BTBD2 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5 KLHL42	1.99e-09	61	157	9	PF07707
Domain	-	KLHL2 KLHL10 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5	2.00e-09	27	157	7	2.130.10.80
Domain	SNF2_N	SMARCA5 CHD4 INO80 CHD5 RAD54B SMARCA1 HELLS	7.32e-09	32	157	7	IPR000330
Domain	SNF2_N	SMARCA5 CHD4 INO80 CHD5 RAD54B SMARCA1 HELLS	7.32e-09	32	157	7	PF00176
Domain	Gal_Oxidase_b-propeller	KLHL2 KLHL10 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5	1.15e-08	34	157	7	IPR015916
Domain	Kelch	KLHL2 KLHL10 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5 KLHL42	2.80e-08	58	157	8	SM00612
Domain	BACK	KLHL2 KLHL10 BTBD2 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5	3.68e-08	60	157	8	SM00875
Domain	Kelch_1	KLHL2 KLHL10 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5 KLHL42	1.27e-07	70	157	8	PF01344
Domain	Kelch_1	KLHL2 KLHL10 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5 KLHL42	1.27e-07	70	157	8	IPR006652
Domain	DBINO	SMARCA5 INO80 SMARCA1	5.83e-07	3	157	3	IPR020838
Domain	DBINO	SMARCA5 INO80 SMARCA1	5.83e-07	3	157	3	PF13892
Domain	Gal_Oxase/kelch_b-propeller	KLHL2 KLHL10 KLHL20 KLHL29 KLHL3 KLHL5 KLHL42	6.13e-07	59	157	7	IPR011043
Domain	BTB	KLHL2 KLHL10 ZBTB8B BTBD2 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5 KLHL42	1.02e-06	160	157	10	PS50097
Domain	BTB-kelch_protein	KLHL2 KLHL10 KLHL20 IVNS1ABP KLHL29 KLHL3	1.51e-06	43	157	6	IPR017096
Domain	BTB	KLHL2 KLHL10 ZBTB8B BTBD2 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5	1.64e-06	131	157	9	PF00651
Domain	BTB/POZ_dom	KLHL2 KLHL10 ZBTB8B BTBD2 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5 KLHL42	3.79e-06	185	157	10	IPR000210
Domain	SKP1/BTB/POZ	KLHL2 KLHL10 ZBTB8B BTBD2 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5 KLHL42	4.59e-06	189	157	10	IPR011333
Domain	FN3	IL13RA1 LRFN3 L1CAM PTPRU CNTN6 IFNGR2 PTPRG PTPRH LRFN5 IL4R	7.24e-06	199	157	10	PS50853
Domain	FN3_dom	IL13RA1 LRFN3 L1CAM PTPRU CNTN6 IFNGR2 PTPRG PTPRH LRFN5 IL4R	1.11e-05	209	157	10	IPR003961
Domain	BTB	KLHL2 KLHL10 ZBTB8B BTBD2 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5	2.19e-05	180	157	9	SM00225
Domain	Helicase_C	SMARCA5 CHD4 INO80 CHD5 RAD54B SMARCA1 HELLS	3.35e-05	107	157	7	PF00271
Domain	HELICc	SMARCA5 CHD4 INO80 CHD5 RAD54B SMARCA1 HELLS	3.35e-05	107	157	7	SM00490
Domain	Helicase_C	SMARCA5 CHD4 INO80 CHD5 RAD54B SMARCA1 HELLS	3.55e-05	108	157	7	IPR001650
Domain	HELICASE_CTER	SMARCA5 CHD4 INO80 CHD5 RAD54B SMARCA1 HELLS	3.77e-05	109	157	7	PS51194
Domain	HELICASE_ATP_BIND_1	SMARCA5 CHD4 INO80 CHD5 RAD54B SMARCA1 HELLS	3.77e-05	109	157	7	PS51192
Domain	DEXDc	SMARCA5 CHD4 INO80 CHD5 RAD54B SMARCA1 HELLS	3.77e-05	109	157	7	SM00487
Domain	Helicase_ATP-bd	SMARCA5 CHD4 INO80 CHD5 RAD54B SMARCA1 HELLS	4.00e-05	110	157	7	IPR014001
Domain	SLIDE	SMARCA5 SMARCA1	7.02e-05	2	157	2	IPR015195
Domain	ISWI_HAND-dom	SMARCA5 SMARCA1	7.02e-05	2	157	2	IPR015194
Domain	SLIDE	SMARCA5 SMARCA1	7.02e-05	2	157	2	PF09111
Domain	HAND	SMARCA5 SMARCA1	7.02e-05	2	157	2	PF09110
Domain	ISWI	SMARCA5 SMARCA1	7.02e-05	2	157	2	IPR029915
Domain	FN3	LRFN3 L1CAM PTPRU CNTN6 IFNGR2 PTPRG PTPRH IL4R	1.73e-04	185	157	8	SM00060
Domain	-	HEXB IDUA SLC3A1 FUCA2	2.05e-04	35	157	4	3.20.20.80
Domain	CHD_N	CHD4 CHD5	2.09e-04	3	157	2	IPR012958
Domain	CHD_C2	CHD4 CHD5	2.09e-04	3	157	2	IPR012957
Domain	CAC1F_C	CACNA1C CACNA1D	2.09e-04	3	157	2	IPR031688
Domain	CHDCT2	CHD4 CHD5	2.09e-04	3	157	2	PF08074
Domain	CHDNT	CHD4 CHD5	2.09e-04	3	157	2	PF08073
Domain	DUF1086	CHD4 CHD5	2.09e-04	3	157	2	IPR009462
Domain	DUF1087	CHD4 CHD5	2.09e-04	3	157	2	IPR009463
Domain	CAC1F_C	CACNA1C CACNA1D	2.09e-04	3	157	2	PF16885
Domain	DUF1087	CHD4 CHD5	2.09e-04	3	157	2	PF06465
Domain	DUF1086	CHD4 CHD5	2.09e-04	3	157	2	PF06461
Domain	DUF1087	CHD4 CHD5	2.09e-04	3	157	2	SM01147
Domain	DUF1086	CHD4 CHD5	2.09e-04	3	157	2	SM01146
Domain	Glyco_hydro_catalytic_dom	HEXB IDUA SLC3A1 FUCA2	2.84e-04	38	157	4	IPR013781
Domain	DEAH_ATP_HELICASE	SMARCA5 CHD4 CHD5 SMARCA1	2.84e-04	38	157	4	PS00690
Domain	Ig-like_fold	IL13RA1 HLA-A LRFN3 L1CAM PTPRU IL18RAP CNTN6 IFNGR2 PTPRG PTPRH PXDNL IGHG2 LRFN5 IGHG4 PKHD1 IL4R	3.06e-04	706	157	16	IPR013783
Domain	VDCC_L_a1su	CACNA1C CACNA1D	4.17e-04	4	157	2	IPR005446
Domain	fn3	LRFN3 L1CAM PTPRU CNTN6 IFNGR2 PTPRG PTPRH	4.45e-04	162	157	7	PF00041
Domain	FYrich_C	KMT2D KMT2A	6.91e-04	5	157	2	IPR003889
Domain	FYrich_N	KMT2D KMT2A	6.91e-04	5	157	2	IPR003888
Domain	FYRC	KMT2D KMT2A	6.91e-04	5	157	2	SM00542
Domain	FYRN	KMT2D KMT2A	6.91e-04	5	157	2	SM00541
Domain	FYRN	KMT2D KMT2A	6.91e-04	5	157	2	PF05964
Domain	FYRC	KMT2D KMT2A	6.91e-04	5	157	2	PF05965
Domain	FYRC	KMT2D KMT2A	6.91e-04	5	157	2	PS51543
Domain	FYRN	KMT2D KMT2A	6.91e-04	5	157	2	PS51542
Domain	P-loop_NTPase	SMARCA5 MYH10 RHOJ ABCC5 MAGI3 CHD4 INO80 TEP1 MDN1 CHD5 RAD54B SMARCA1 NAV1 SEPTIN7 HYDIN ABCG8 HELLS	7.98e-04	848	157	17	IPR027417
Domain	Glycoside_hydrolase_SF	HEXB IDUA SLC3A1 FUCA2	1.02e-03	53	157	4	IPR017853
Domain	Ca_chan_IQ	CACNA1C CACNA1D	1.43e-03	7	157	2	SM01062
Domain	Ca_chan_IQ	CACNA1C CACNA1D	1.43e-03	7	157	2	PF08763
Domain	VDCC_a1su_IQ	CACNA1C CACNA1D	1.43e-03	7	157	2	IPR014873
Domain	GPHH	CACNA1C CACNA1D	1.43e-03	7	157	2	PF16905
Domain	GPHH_dom	CACNA1C CACNA1D	1.43e-03	7	157	2	IPR031649
Domain	-	SMARCA5 RHOJ ABCC5 CHD4 INO80 TEP1 MDN1 CHD5 RAD54B SMARCA1 NAV1 SEPTIN7 HYDIN ABCG8 HELLS	1.58e-03	746	157	15	3.40.50.300
Domain	MBT	SFMBT2 L3MBTL4	2.43e-03	9	157	2	SM00561
Domain	MBT	SFMBT2 L3MBTL4	2.43e-03	9	157	2	PS51079
Domain	ZF_SWIM	ZSWIM5 ZSWIM6	2.43e-03	9	157	2	PS50966
Domain	Znf_SWIM	ZSWIM5 ZSWIM6	2.43e-03	9	157	2	IPR007527
Domain	MBT	SFMBT2 L3MBTL4	3.02e-03	10	157	2	PF02820
Domain	Mbt	SFMBT2 L3MBTL4	3.02e-03	10	157	2	IPR004092
Domain	VDCCAlpha1	CACNA1C CACNA1D	3.02e-03	10	157	2	IPR002077
Domain	DNA/RNA_helicase_DEAH_CS	SMARCA5 CHD4 CHD5	3.13e-03	35	157	3	IPR002464
Domain	PTPc	PTPRU PTPRG PTPRH	3.39e-03	36	157	3	SM00194
Domain	PHD	CHD4 KMT2D CHD5 KMT2A	3.68e-03	75	157	4	PF00628
Pubmed	Update on the Kelch-like (KLHL) gene family.	KLHL2 KLHL10 KLHL20 KLHL29 KLHL3 KLHL5 KLHL42	6.90e-10	41	158	7	23676014
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	CACNA1C SMARCA5 NPEPPS CDKN2AIP SPTBN2 FNBP4 RRBP1 LCP2 MDN1 KIAA0825 FGA KMT2A ANO3 HYDIN HELLS	9.75e-09	497	158	15	36774506
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	HEXB MYH10 ITCH AOC1 CEL RHOJ CDHR2 NPEPPS CAPN1 LAMC1 IDUA PROM1 PTPRG IGHG2 IGHG4 FGA FUCA2 NME1 CDH1	4.50e-07	1070	158	19	23533145
Pubmed	Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis.	KMT2D IGHG2 IGHG4	1.82e-06	6	158	3	26366712
Pubmed	Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment.	KMT2D IGHG2 IGHG4	1.82e-06	6	158	3	38570506
Pubmed	A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.	KLHL2 BTBD2 KLHL20 IVNS1ABP KLHL5 KLHL42	2.98e-06	87	158	6	37495603
Pubmed	Murine germinal center B cells require functional Fms-like tyrosine kinase 3 signaling for IgG1 class-switch recombination.	IGHG2 IGHG4 IL4R	3.18e-06	7	158	3	26627255
Pubmed	Functional proteomics mapping of a human signaling pathway.	USP13 MYH10 RMND5A FNBP4 LAMC1 BTBD2 RRBP1 RFX1 GGA3 EPG5 KMT2D MTMR11 INVS	3.38e-06	591	158	13	15231748
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	MYH10 FNBP4 LAMC1 CHD4 RRBP1 URB1 PKHD1 KMT2A	4.31e-06	202	158	8	24639526
Pubmed	Novel CUL3 Variant Causing Familial Hyperkalemic Hypertension Impairs Regulation and Function of Ubiquitin Ligase Activity.	BTBD2 KLHL20 KLHL3 KLHL5 KLHL42	6.28e-06	57	158	5	34878901
Pubmed	Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation.	IGHG2 IGHG4 IL4R	1.08e-05	10	158	3	34555336
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CACNA1C MYH10 PDE4D ITCH NPEPPS CAPN1 FNBP4 STAP2 MAGI3 ZSWIM6 RRBP1 NEDD1 TEP1 SFMBT2 KLHL29 PTPRG GALNT11 NAV1 CSMD1 INVS	1.49e-05	1489	158	20	28611215
Pubmed	Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor alpha1 chain.	IL13RA1 IL4R	2.05e-05	2	158	2	18066066
Pubmed	Praja2 suppresses the growth of gastric cancer by ubiquitylation of KSR1 and inhibiting MEK-ERK signal pathways.	PJA2 KSR1	2.05e-05	2	158	2	33461174
Pubmed	Recurrence and cancer-specific survival according to the expression of IL-4Rα and IL-13Rα1 in patients with oral cavity cancer.	IL13RA1 IL4R	2.05e-05	2	158	2	25483786
Pubmed	cDNA cloning and characterization of the human interleukin 13 receptor alpha chain.	IL13RA1 IL4R	2.05e-05	2	158	2	8910586
Pubmed	Different roles attributed to Cav1 channel subtypes in spontaneous action potential firing and fine tuning of exocytosis in mouse chromaffin cells.	CACNA1C CACNA1D	2.05e-05	2	158	2	21054386
Pubmed	An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.	CACNA1C CACNA1D	2.05e-05	2	158	2	24086669
Pubmed	Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3.	CACNA1C CACNA1D	2.05e-05	2	158	2	26049024
Pubmed	Single cell analysis of ligand binding and complex formation of interleukin-4 receptor subunits.	IL13RA1 IL4R	2.05e-05	2	158	2	22098734
Pubmed	Set1 and MLL1/2 Target Distinct Sets of Functionally Different Genomic Loci In Vivo.	KMT2D KMT2A	2.05e-05	2	158	2	26711341
Pubmed	Targeting of IL-4 and IL-13 receptors for cancer therapy.	IL13RA1 IL4R	2.05e-05	2	158	2	26088753
Pubmed	Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers.	CACNA1C CACNA1D	2.05e-05	2	158	2	19225208
Pubmed	Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB.	CACNA1C CACNA1D	2.05e-05	2	158	2	16706838
Pubmed	Temperature-sensitive Cav1.2 calcium channels support intrinsic firing of pyramidal neurons and provide a target for the treatment of febrile seizures.	CACNA1C CACNA1D	2.05e-05	2	158	2	23761887
Pubmed	The role of calpain in the proteolytic cleavage of E-cadherin in prostate and mammary epithelial cells.	CAPN1 CDH1	2.05e-05	2	158	2	12393869
Pubmed	Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits.	CACNA1C CACNA1D	2.05e-05	2	158	2	14981074
Pubmed	CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum.	CACNA1C CACNA1D	2.05e-05	2	158	2	25292336
Pubmed	Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle.	CACNA1C CACNA1D	2.05e-05	2	158	2	17526649
Pubmed	Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant.	KMT2D KMT2A	2.05e-05	2	158	2	24423662
Pubmed	Ligand-activated signal transduction in the 2-cell embryo.	CACNA1C CACNA1D	2.05e-05	2	158	2	12606379
Pubmed	Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.	CACNA1C CACNA1D	2.05e-05	2	158	2	24941892
Pubmed	Analysis of a non-synonymous single nucleotide polymorphism of the human diamine oxidase gene (ref. SNP ID: rs1049793) in patients with Crohn's disease.	AOC1 DAO	2.05e-05	2	158	2	19670078
Pubmed	Equal sensitivity of Cav1.2 and Cav1.3 channels to the opposing modulations of PKA and PKG in mouse chromaffin cells.	CACNA1C CACNA1D	2.05e-05	2	158	2	22826131
Pubmed	Two mutations produce intron insertion in mRNA and elongated beta-subunit of human beta-hexosaminidase.	HEXB IDUA	2.05e-05	2	158	2	2170400
Pubmed	Transcriptional regulation of L-type calcium channel subtypes Cav1.2 and Cav1.3 by nicotine and their potential role in nicotine sensitization.	CACNA1C CACNA1D	2.05e-05	2	158	2	24470632
Pubmed	An environmentally regulated receptor for diamine oxidase modulates human endothelial cell/fibroblast histamine degradative uptake.	AOC1 DAO	2.05e-05	2	158	2	8195119
Pubmed	CHD4-mediated loss of E-cadherin determines metastatic ability in triple-negative breast cancer cells.	CHD4 CDH1	2.05e-05	2	158	2	29305962
Pubmed	Perisomatic GABAergic innervation in prefrontal cortex is regulated by ankyrin interaction with the L1 cell adhesion molecule.	L1CAM CDH1	2.05e-05	2	158	2	20156840
Pubmed	Cav1.2 and Cav1.3 L-type calcium channels operate in a similar voltage range but show different coupling to Ca(2+)-dependent conductances in hippocampal neurons.	CACNA1C CACNA1D	2.05e-05	2	158	2	24760982
Pubmed	Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons.	CACNA1C CACNA1D	2.05e-05	2	158	2	20014384
Pubmed	The human gene for diamine oxidase, an amiloride binding protein. Molecular cloning, sequencing, and characterization of the promoter.	AOC1 DAO	2.05e-05	2	158	2	8182053
Pubmed	Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway.	KSR1 NME1	2.05e-05	2	158	2	12105213
Pubmed	Commentary: IL-4 and IL-13 receptors and signaling.	IL13RA1 IL4R	2.05e-05	2	158	2	26187331
Pubmed	Role of putative voltage-sensor countercharge D4 in regulating gating properties of CaV1.2 and CaV1.3 calcium channels.	CACNA1C CACNA1D	2.05e-05	2	158	2	30001160
Pubmed	Expression of IL4Rα and IL13Rα1 are associated with poor prognosis of soft-tissue sarcoma of the extremities, superficial trunk, and retroperitoneum.	IL13RA1 IL4R	2.05e-05	2	158	2	33419470
Pubmed	Identification, molecular cloning, and characterization of a novel GABAA receptor-associated protein, GRIF-1.	GABRB2 TRAK2	2.05e-05	2	158	2	12034717
Pubmed	praja2 regulates KSR1 stability and mitogenic signaling.	PJA2 KSR1	2.05e-05	2	158	2	27195677
Pubmed	Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.	CACNA1C CACNA1D	2.05e-05	2	158	2	21352396
Pubmed	Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells.	CACNA1C CACNA1D	2.05e-05	2	158	2	17409250
Pubmed	Neuronal L-type calcium channels open quickly and are inhibited slowly.	CACNA1C CACNA1D	2.05e-05	2	158	2	16267232
Pubmed	Association between PTCH1 and RAD54B single-nucleotide polymorphisms and non-syndromic orofacial clefts in a northern Chinese population.	PTCH1 RAD54B	2.05e-05	2	158	2	30172247
Pubmed	The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function.	CACNA1C CACNA1D	2.05e-05	2	158	2	24996399
Pubmed	Expression of E-cadherin and nm23 is associated with the clinicopathological factors of human non-small cell lung cancer in China.	NME1 CDH1	2.05e-05	2	158	2	15777972
Pubmed	Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons.	CACNA1C CACNA1D	2.05e-05	2	158	2	24849370
Pubmed	Divide and conquer: an L-type voltage-gated calcium channel subtype finds a role in conditioned fear.	CACNA1C CACNA1D	2.05e-05	2	158	2	17015854
Pubmed	Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area.	CACNA1C CACNA1D	2.05e-05	2	158	2	24848473
Pubmed	Remote ischemic preconditioning reduces mitochondrial apoptosis mediated by calpain 1 activation in myocardial ischemia-reperfusion injury through calcium channel subunit Cacna2d3.	CAPN1 CACNA2D3	2.05e-05	2	158	2	38151212
Pubmed	Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor.	IL13RA1 IL4R	2.05e-05	2	158	2	8552669
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	HEXB USP13 DMXL2 ITCH HLA-A ZRSR2 CEP85L SPTBN2 TTC27 ABCC5 MAGI3 CHD4 BTBD2 RRBP1 CEP350 SCG2 SEPTIN7 COG4	2.38e-05	1285	158	18	35914814
Pubmed	The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.	SMARCA5 KMT2D KMT2A	2.54e-05	13	158	3	16510874
Pubmed	Large-scale identification of mammalian proteins localized to nuclear sub-compartments.	ITCH ZRSR2 KMT2A HELLS	2.68e-05	38	158	4	11555636
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	DMXL2 ENPP7 RHOJ CAPN1 BCL2L1 PTPRU KLHL20 KLHL3 KLHL5 KAT2B GALNT11 KMT2A KCNH5	3.15e-05	730	158	13	34857952
Pubmed	The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny.	CHD4 PTCH1 CDH1	3.23e-05	14	158	3	17360773
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1C CACNA1D CACNA2D3	4.02e-05	15	158	3	20188150
Pubmed	Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.	SMARCA5 KMT2D KMT2A	4.02e-05	15	158	3	16510875
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1C CACNA1D CACNA2D3	4.02e-05	15	158	3	24453333
Pubmed	Absence of annulus in human asthenozoospermia: case report.	SLC26A8 SEPTIN7	6.13e-05	3	158	2	19221096
Pubmed	Nm23-H1 metastasis suppressor expression level influences the binding properties, stability, and function of the kinase suppressor of Ras1 (KSR1) Erk scaffold in breast carcinoma cells.	KSR1 NME1	6.13e-05	3	158	2	15684389
Pubmed	A three-gene expression signature model for risk stratification of patients with neuroblastoma.	CHD5 NME1	6.13e-05	3	158	2	22328561
Pubmed	CD133 expression correlates with membrane beta-catenin and E-cadherin loss from human hair follicle placodes during morphogenesis.	PROM1 CDH1	6.13e-05	3	158	2	25010141
Pubmed	Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).	CACNA1C CACNA1D	6.13e-05	3	158	2	17767505
Pubmed	Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.	KMT2D KMT2A	6.13e-05	3	158	2	26902498
Pubmed	Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.	CACNA1C CACNA1D	6.13e-05	3	158	2	2173707
Pubmed	Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.	KMT2D KMT2A	6.13e-05	3	158	2	23932714
Pubmed	Polymorphisms in the IL13, IL13RA1, and IL4RA genes and rate of decline in lung function in smokers.	IL13RA1 IL4R	6.13e-05	3	158	2	12594065
Pubmed	Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.	PTCH1 KMT2D	6.13e-05	3	158	2	22183980
Pubmed	G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.	CACNA1C CACNA1D	6.13e-05	3	158	2	26831068
Pubmed	Essential Role of Linx/Islr2 in the Development of the Forebrain Anterior Commissure.	L1CAM CDH1	6.13e-05	3	158	2	29739947
Pubmed	Human INO80 chromatin-remodelling complex contributes to DNA double-strand break repair via the expression of Rad54B and XRCC3 genes.	INO80 RAD54B	6.13e-05	3	158	2	20687897
Pubmed	Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesion.	PTPRU CDH1	6.13e-05	3	158	2	16574648
Pubmed	Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes.	CACNA1C CACNA1D	6.13e-05	3	158	2	23338940
Pubmed	Role of IL-4 in bone marrow driven dysregulated angiogenesis and age-related macular degeneration.	IL13RA1 IL4R	6.13e-05	3	158	2	32366355
Pubmed	The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts.	CACNA1C CACNA1D	6.13e-05	3	158	2	19351867
Pubmed	NDRG2 positively regulates E-cadherin expression and prolongs overall survival in colon cancer patients.	NDRG2 CDH1	6.13e-05	3	158	2	23900729
Pubmed	Truncation of murine CaV1.2 at Asp-1904 results in heart failure after birth.	CACNA1C CACNA1D	6.13e-05	3	158	2	21832054
Pubmed	Binding kinetics of human ISWI chromatin-remodelers to DNA repair sites elucidate their target location mechanism.	SMARCA5 SMARCA1	6.13e-05	3	158	2	21738833
Pubmed	Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.	CACNA1C CACNA1D	6.13e-05	3	158	2	17289261
Pubmed	Cloning and characterization of the murine Imitation Switch (ISWI) genes: differential expression patterns suggest distinct developmental roles for Snf2h and Snf2l.	SMARCA5 SMARCA1	6.13e-05	3	158	2	11359880
Pubmed	Potent inhibition of L-type Ca2+ currents by a Rad variant associated with congestive heart failure.	CACNA1C CACNA1D	6.13e-05	3	158	2	23973784
Pubmed	Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation.	LRFN3 LRFN5	6.13e-05	3	158	2	20410109
Pubmed	MicroRNA-1976 regulates degeneration of the sinoatrial node by targeting Cav1.2 and Cav1.3 ion channels.	CACNA1C CACNA1D	6.13e-05	3	158	2	31302118
Pubmed	Distinct localization and modulation of Cav1.2 and Cav1.3 L-type Ca2+ channels in mouse sinoatrial node.	CACNA1C CACNA1D	6.13e-05	3	158	2	23045342
Pubmed	Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons.	CACNA1C CACNA1D	6.13e-05	3	158	2	24934288
Pubmed	MLL histone methylases regulate expression of HDLR-SR-B1 in presence of estrogen and control plasma cholesterol in vivo.	KMT2D KMT2A	6.13e-05	3	158	2	23192982
Pubmed	On the Role IL-4/IL-13 Heteroreceptor Plays in Regulation of Type 1 Diabetes.	IL13RA1 IL4R	6.13e-05	3	158	2	28646042
Pubmed	Differential expression of flectin in the extracellular matrix and left-right asymmetry in mouse embryonic heart during looping stages.	MYH10 INVS	6.13e-05	3	158	2	9842715
Pubmed	The Contribution of Mosaic Variants to Autism Spectrum Disorder.	MYH10 KMT2D	6.13e-05	3	158	2	27632392
Pubmed	Integration of global spectral karyotyping, CGH arrays, and expression arrays reveals important genes in the pathogenesis of glioblastoma multiforme.	PROM1 CACNA2D3	6.13e-05	3	158	2	22395973
Pubmed	Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.	KMT2D KMT2A	6.13e-05	3	158	2	30315824
Interaction	DAO interactions	AOC1 DAO PEX5 KLHL42	1.63e-06	12	156	4	int:DAO
GeneFamily	Kelch like\|BTB domain containing	KLHL2 KLHL10 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5 KLHL42	2.21e-10	42	116	8	617
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL2 KLHL10 ZBTB8B BTBD2 KLHL20 IVNS1ABP KLHL29 KLHL3 KLHL5	2.01e-07	134	116	9	861
GeneFamily	Fibronectin type III domain containing	LRFN3 L1CAM PTPRU CNTN6 IFNGR2 PTPRG PTPRH LRFN5	8.93e-06	160	116	8	555
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRU PTPRG PTPRH	3.15e-04	21	116	3	813
GeneFamily	Calcium voltage-gated channel subunits	CACNA1C CACNA1D CACNA2D3	6.01e-04	26	116	3	253
GeneFamily	Zinc fingers SWIM-type\|Mitogen-activated protein kinase kinase kinases	ZSWIM5 ZSWIM6	1.43e-03	9	116	2	90
GeneFamily	Sterile alpha motif domain containing\|MBT domain containing	SFMBT2 L3MBTL4	1.43e-03	9	116	2	1263
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL13RA1 IL18RAP IL4R	2.46e-03	42	116	3	602
GeneFamily	PHD finger proteins\|NuRD complex	CHD4 CHD5	2.58e-03	12	116	2	1305
GeneFamily	PHD finger proteins	CHD4 KMT2D CHD5 KMT2A	2.69e-03	90	116	4	88
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	LRFN3 L1CAM CNTN6 PXDNL LRFN5	3.82e-03	161	116	5	593
GeneFamily	DNA helicases	INO80 HELLS	5.21e-03	17	116	2	1167
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRB2 GABRG3	6.50e-03	19	116	2	563
GeneFamily	Polypeptide N-acetylgalactosaminyltransferases	GALNT11 GALNTL5	7.19e-03	20	116	2	433
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	L1CAM ZBTB8B CNTN6 TG CHD5 AIPL1 ELAVL4 NRSN1	2.71e-07	180	158	8	7d3d5608647b6e684e8e185993d106a38c53e76a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D SLC3A1 IVNS1ABP PROM1 PKHD1 CDH1 HYDIN CACNA2D3	4.79e-07	194	158	8	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KLHL2 DMXL2 ABCC5 ZSWIM6 LCP2 IVNS1ABP IFNGR2 SPIC	4.79e-07	194	158	8	663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRG3 CACNA1C CACNA1D MYH10 LRFN5 CHD5 CSMD1	5.18e-07	196	158	8	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRG3 CACNA1C CACNA1D LRFN5 CHD5 CSMD1 CACNA2D3	5.59e-07	198	158	8	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRG3 CACNA1C MYH10 LRFN5 CHD5 CSMD1 CACNA2D3	5.59e-07	198	158	8	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRG3 CACNA1C CACNA1D MYH10 LRFN5 CHD5 CSMD1	5.59e-07	198	158	8	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Sigmoid-(5)_Dendritic_cell-(50)_cDC2\|Sigmoid / shred on region, Cell_type, and subtype	IL13RA1 DAO NDRG2 ZNF516 NAV1 ELAVL4 PID1 CACNA2D3	5.81e-07	199	158	8	402af84db90d8a49d67cf44c24766aefb00fd716
ToppCell	Sigmoid-Dendritic_cell-cDC2\|Sigmoid / Region, Cell class and subclass	IL13RA1 DAO NDRG2 ZNF516 NAV1 ELAVL4 PID1 CACNA2D3	5.81e-07	199	158	8	cd74db6db694b68f81dcf9d9342d125d00357ec1
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1C CDHR2 SFMBT2 CNTN6 PKHD1 HYDIN L3MBTL4	1.86e-06	162	158	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 PDE4D SPTBN2 L1CAM PKHD1 CDH1 HELLS	2.56e-06	170	158	7	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GABRG3 IL13RA1 NDRG2 MTMR11 NAV1 PID1 CACNA2D3	2.56e-06	170	158	7	7bba77ae34a0259fad6ee98cf665ff50f77a1328
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GABRG3 IL13RA1 NDRG2 MTMR11 NAV1 PID1 CACNA2D3	2.56e-06	170	158	7	a43b977a7fe745536cf96b7c080397d9fa73086b
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1C RHOJ LAMC1 CCDC80 PTPRG NAV1 PID1	4.02e-06	182	158	7	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	L1CAM LRFN5 CHD5 ELAVL4 ASIC4 NRSN1 KCNH5	4.17e-06	183	158	7	7e2bac8b005155888ff4b41ef2e1d975dc17abc7
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 ODAD2 PKHD1 ELAVL4 CSMD1 ANO3 HYDIN	4.32e-06	184	158	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	COVID-19_Convalescent-Myeloid-cDC\|COVID-19_Convalescent / Disease group, lineage and cell class	IL13RA1 NDRG2 NHSL1 NAV1 CDH1 PID1 CACNA2D3	4.32e-06	184	158	7	ad6e910eaebe841a68a5f2f329d43dafc5db158a
ToppCell	PBMC-Convalescent-Myeloid-cDC-cDC\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IL13RA1 NDRG2 NHSL1 NAV1 CDH1 PID1 CACNA2D3	4.32e-06	184	158	7	9d678b24532b7763f2e73f7ccb496259977c5204
ToppCell	PBMC-Convalescent-Myeloid-cDC-cDC-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IL13RA1 NDRG2 NHSL1 NAV1 CDH1 PID1 CACNA2D3	4.32e-06	184	158	7	383374ad17bd322b8d703a22e475d34ca7b2e6b6
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 ODAD2 PKHD1 ELAVL4 CSMD1 ANO3 HYDIN	4.32e-06	184	158	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	PBMC-Convalescent-Myeloid-cDC\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	IL13RA1 NDRG2 NHSL1 NAV1 CDH1 PID1 CACNA2D3	4.32e-06	184	158	7	5535b85b3ad3d0c0392d5884fdc2939c7e1b1c3e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 ODAD2 PKHD1 ELAVL4 CSMD1 ANO3 HYDIN	4.32e-06	184	158	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	DMXL2 HLA-A WDR43 URB1 KMT2D INVS HELLS	4.48e-06	185	158	7	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D PDE4D SLC3A1 KLHL29 PKHD1 HYDIN L3MBTL4	4.64e-06	186	158	7	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	CACNA1C CACNA1D MYH10 RHOJ LAMC1 PTPRG LRFN5	4.81e-06	187	158	7	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CEP85L MAGI3 RGS9 IVNS1ABP KMT2A GASK1A	4.98e-06	188	158	7	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CEP85L MAGI3 RGS9 IVNS1ABP KMT2A GASK1A	4.98e-06	188	158	7	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CEP85L MAGI3 RGS9 IVNS1ABP KMT2A GASK1A	4.98e-06	188	158	7	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	GABRB2 CACNA1D PDE4D INO80 PTPRG MAP3K13 PID1	4.98e-06	188	158	7	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CACNA1D CCDC80 PTCH1 PROM1 PXDNL GASK1A	5.53e-06	191	158	7	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C CACNA1D MYH10 LAMC1 PTPRG LRFN5 ANO3	5.53e-06	191	158	7	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 PDE4D AOC1 SPTBN2 L1CAM CDH1 HELLS	5.72e-06	192	158	7	9e031bf93eb8757fdd0cc22f01b44e48f85532d5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 PDE4D AOC1 SPTBN2 L1CAM CDH1 HELLS	5.72e-06	192	158	7	3d777d07878269b87ec7e1f06489cae7c989d633
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HEXB IL13RA1 NDRG2 MTMR11 NAV1 PID1 CACNA2D3	5.92e-06	193	158	7	6b3a2a32ec6dc96230cee4bbf03932f8a81e6683
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM TUB LRFN5 CHD5 ELAVL4 NRSN1 KCNH5	5.92e-06	193	158	7	461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM TUB LRFN5 CHD5 ELAVL4 NRSN1 KCNH5	5.92e-06	193	158	7	0dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HEXB IL13RA1 NDRG2 MTMR11 NAV1 PID1 CACNA2D3	5.92e-06	193	158	7	b18c61e360f5f094f260007a56b189e2a48369e4
ToppCell	Thalamus-Neuronal\|Thalamus / BrainAtlas - Mouse McCarroll V32	SPTBN2 PJA2 LRFN5 SCG2 CHD5 ELAVL4 NRSN1	5.92e-06	193	158	7	712a4acd1167e43543950bc819ff11984e6f718d
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C CACNA1D MYH10 RHOJ LAMC1 NDRG2 PTPRG	6.12e-06	194	158	7	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-MGE2\|World / Primary Cells by Cluster	GABRG3 KLHL5 NRXN2 CHD5 ELAVL4 ASIC4 SEPTIN7	6.12e-06	194	158	7	b42fd64b0fb95434a9e4e6586f31d26114a4074b
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-MGE2-10\|World / Primary Cells by Cluster	GABRG3 KLHL5 NRXN2 CHD5 ELAVL4 ASIC4 SEPTIN7	6.12e-06	194	158	7	81e7bc6516ab8d02ccd1c76a56a3533b788c27c8
ToppCell	IIF-Myeloid-cDC\|IIF / Disease, Lineage and Cell Type	HEXB IL13RA1 NDRG2 MTMR11 FUCA2 PID1 CACNA2D3	6.33e-06	195	158	7	81225852a5827e973cb3b1da5c41e93d5407ecb6
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	CACNA1C CACNA1D MYH10 RHOJ LAMC1 ANO3 CACNA2D3	6.33e-06	195	158	7	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC3A1 IVNS1ABP PROM1 PKHD1 CDH1 HYDIN CACNA2D3	6.55e-06	196	158	7	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C CACNA1D MYH10 LAMC1 CCDC80 PTPRG LRFN5	6.55e-06	196	158	7	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	GABRB2 L1CAM NRXN2 LRFN5 SCG2 CHD5 CACNA2D3	6.77e-06	197	158	7	4961f66606f08e399508fd6cabca588e7ab406a8
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HEXB IL13RA1 NDRG2 MTMR11 NAV1 PID1 CACNA2D3	6.99e-06	198	158	7	c1fe38594bd6292fcc60bdbb563376b454731d00
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRG3 CACNA1C CACNA1D LRFN5 CHD5 CSMD1	6.99e-06	198	158	7	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	CACNA1C CACNA1D MYH10 RHOJ LAMC1 CCDC80 LRFN5	6.99e-06	198	158	7	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	CACNA1C CACNA1D MYH10 LAMC1 CCDC80 PTPRG LRFN5	6.99e-06	198	158	7	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C CACNA1D MYH10 LAMC1 CCDC80 PTPRG LRFN5	6.99e-06	198	158	7	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRG3 CACNA1C CACNA1D LRFN5 CHD5 CSMD1	6.99e-06	198	158	7	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HEXB IL13RA1 NDRG2 MTMR11 NAV1 PID1 CACNA2D3	6.99e-06	198	158	7	bfc15de70a7577a2860b53e1e6826a7b5ad23040
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MAGI3 LAMC1 PTPRU CNTN6 PKHD1 CDH1 CACNA2D3	7.23e-06	199	158	7	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	L1CAM NRXN2 SCG2 CHD5 ELAVL4 ASIC4 NRSN1	7.23e-06	199	158	7	ce8dbfd969b3b9c08e1c57c2bfd899818e878731
ToppCell	Caecum-(5)_Dendritic_cell-(50)_cDC2\|Caecum / shred on region, Cell_type, and subtype	IL13RA1 NDRG2 NHSL1 NRXN2 ELAVL4 PID1 CACNA2D3	7.23e-06	199	158	7	bf8a10a9db7e8e0a6e2b53747949f442fe0e581e
ToppCell	Caecum-Dendritic_cell-cDC2\|Caecum / Region, Cell class and subclass	IL13RA1 NDRG2 NHSL1 NRXN2 ELAVL4 PID1 CACNA2D3	7.23e-06	199	158	7	944c567307082dd54dc141e93965d46f4ec8bc1f
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 PDE4D L1CAM ABCC5 KLHL3 PKHD1 CDH1	7.23e-06	199	158	7	3cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	GABRB2 GABRG3 CACNA1C CACNA1D LRFN5 CHD5 CSMD1	7.47e-06	200	158	7	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Sigmoid-Dendritic_cell\|Sigmoid / Region, Cell class and subclass	IL13RA1 NDRG2 ZNF516 NAV1 ELAVL4 PID1 CACNA2D3	7.47e-06	200	158	7	994a49317b806d115c630cd90897a91fc85ff467
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C LAMC1 CCDC80 PTPRG LRFN5 NAV1 PID1	7.47e-06	200	158	7	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	MS-IIF-Myeloid-cDC\|IIF / Disease, condition lineage and cell class	HEXB IL13RA1 NDRG2 MTMR11 FUCA2 PID1 CACNA2D3	7.47e-06	200	158	7	620a82805619d113182d59740670c9f9b93ee924
ToppCell	LPS_only-Epithelial_alveolar-AT_1\|LPS_only / Treatment groups by lineage, cell group, cell type	STAP2 MAGI3 PTPRU CNTN6 PKHD1 CDH1 CACNA2D3	7.47e-06	200	158	7	9a6ae40f3e17cd44ee5fd73260713b920aa2ea15
ToppCell	Sigmoid-(5)_Dendritic_cell\|Sigmoid / shred on region, Cell_type, and subtype	IL13RA1 NDRG2 ZNF516 NAV1 ELAVL4 PID1 CACNA2D3	7.47e-06	200	158	7	1130328863a4fcfa7dcd7261e9905943057777c5
ToppCell	COVID-19-COVID-19_Convalescent-Myeloid-cDC\|COVID-19_Convalescent / Disease, condition lineage and cell class	IL13RA1 NDRG2 NHSL1 NAV1 CDH1 PID1 CACNA2D3	7.47e-06	200	158	7	ac9d7927863348a752444d2e80269a5eead943b7
ToppCell	MS-Multiple_Sclerosis-Myeloid-cDC\|Multiple_Sclerosis / Disease, condition lineage and cell class	HEXB IL13RA1 NDRG2 MTMR11 NAV1 PID1 CACNA2D3	7.47e-06	200	158	7	d9e6c344c59544c87bc13d1e866491da432c9c1b
ToppCell	(50)_cDC2\|World / shred on Cell_type and subtype	IL13RA1 NDRG2 NRXN2 NAV1 ELAVL4 PID1 CACNA2D3	9.05e-06	206	158	7	d519adeb8290fcce107e81a439ba3bf1e231b55b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D PDE4D SPTBN2 MAGI3 KLHL3 CDH1	1.61e-05	150	158	6	87968ce885a4959616f0321f58517fe8029ba1b1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL10 MYH10 PDE4D SPTBN2 L1CAM CDH1	2.01e-05	156	158	6	a4b0e89255ea5d60198cb2b3e739981f9c9cf5c5
ToppCell	COVID-CD4-CD4_Treg\|COVID / Condition, Cell_class and T cell subcluster	ZNF12 KLHL3 KMT2D PXYLP1 ZNF682 HELLS	2.23e-05	159	158	6	037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PTCH1 ZNF12 PROM1 TRAK2 ANO3 ABCG8	2.66e-05	164	158	6	583dda853cee9491dbdcb228c23d8deadc20eb08
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE4D CEP85L ZSWIM5 STAP2 PTCH1 CSMD1	2.75e-05	165	158	6	6d315e0734079ad05336cc2c3f24d870c9105bc8
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE4D CEP85L ZSWIM5 STAP2 PTCH1 CSMD1	2.75e-05	165	158	6	84f5597b1bb75f42de9a224196bb8ac198bbe3bf
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RHOJ RGS9 PTPRU KLHL5 IL4R KCNH5	3.04e-05	168	158	6	7abaddbcc55e44653d54aa15464266aa6bd5c9d2
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_dendritic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NDRG2 NRXN2 IGHG2 NAV1 CDH1 CACNA2D3	3.36e-05	171	158	6	c2b7bbabc8f9afa8a1157b567d5f962d4b242919
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Microglia/Mac\|metastatic_Lymph_Node / Location, Cell class and cell subclass	ABCC5 GGA3 KLHL3 SLC26A8 GALNT11 NAV1	3.47e-05	172	158	6	f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCell	URO-Lymphocyte-T_NK-gdT\|URO / Disease, Lineage and Cell Type	HLA-A STK17A RGS9 IL18RAP ASIC4 SEPTIN7	3.47e-05	172	158	6	97b1eb95234639fcaa5ea3c4ba7ec2f4eb929dbf
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRXN2 SCG2 CHD5 LRP11 ELAVL4 ASIC4	3.71e-05	174	158	6	742c73c9e090848b464323cb17579b86658c6792
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CACNA1D MYH10 NDRG2 PROM1 SLC13A4 PID1	3.71e-05	174	158	6	3c47d069bd836599a8d40eae485c23d4d3487517
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRXN2 SCG2 CHD5 LRP11 ELAVL4 ASIC4	3.71e-05	174	158	6	7fed9722e64c60843092f2ba71256e3043011ef6
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CYP26B1 RHOJ RGS9 PTPRU IL4R KCNH5	3.71e-05	174	158	6	321c6cae614d28feeee266eeb3499f2053ab79e0
ToppCell	pdx-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CACNA1D CDHR2 TFR2 MAP3K13 CDH1 L3MBTL4	3.95e-05	176	158	6	1e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN2 L1CAM ELAVL4 ASIC4 NRSN1 KCNH5	3.95e-05	176	158	6	bfea433544c6d6b8ad55e50ca94c5574460c2e0b
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN2 L1CAM ELAVL4 ASIC4 NRSN1 KCNH5	3.95e-05	176	158	6	3c78dee7e1111a579fde6d401b9ecb4d5b8e782f
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D MAGI3 CCDC80 CNTN6 PXDNL CACNA2D3	4.08e-05	177	158	6	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RHOJ RGS9 PTPRU KLHL5 IL4R KCNH5	4.21e-05	178	158	6	431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PDE4D ZNF486 MAGI3 NRSN1 CDH1 ZNF682	4.21e-05	178	158	6	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RMND5A CCNDBP1 BCL2L1 TFR2 NARF TRAK2	4.34e-05	179	158	6	7329b45376a9e9a4fe34d4aa0b33af6dda0a8e3b
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RMND5A CCNDBP1 BCL2L1 TFR2 NARF TRAK2	4.34e-05	179	158	6	6e4740f99f66d3e9348fa5057cf1030454819aa8
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid-Erythroid\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RMND5A CCNDBP1 BCL2L1 TFR2 NARF TRAK2	4.34e-05	179	158	6	ee60ac43fb62c09967a26bbcf9306ac5ea2bdc1e
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CYP26B1 RHOJ RGS9 PTPRU IL4R KCNH5	4.48e-05	180	158	6	b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AOC1 CDHR2 PTPRH CDH1 ANO3 ABCG8	4.62e-05	181	158	6	1d3d1b5a6efe9cedd03b7e0b5684df97f0246729
ToppCell	facs-GAT-Fat-3m-Epithelial-epithelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAO ODAD2 PROM1 PKHD1 CDH1 HYDIN	4.62e-05	181	158	6	e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCell	VE-matDC\|VE / Condition, Cell_class and T cell subcluster	IL13RA1 AOC1 PTPRG NRXN2 NAV1 SPIC	4.62e-05	181	158	6	982fd96ef75bc9ab2c2f4970c01b76ba7a164871
ToppCell	facs-GAT-Fat-3m-Epithelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAO ODAD2 PROM1 PKHD1 CDH1 HYDIN	4.62e-05	181	158	6	11cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCell	VE-matDC-\|VE / Condition, Cell_class and T cell subcluster	IL13RA1 AOC1 PTPRG NRXN2 NAV1 SPIC	4.62e-05	181	158	6	6252184ef098b911df50be4fe1b5565849a5b6b8
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HLA-A CCDC80 CNTN6 SCG2 ASIC4 L3MBTL4	4.62e-05	181	158	6	154d5e586cab25155c6d06dfe6ae01203b88e0fb
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AOC1 CDHR2 PTPRH CDH1 ANO3 ABCG8	4.62e-05	181	158	6	0069e8308de932df43660bbe926637c57b8bf7f6
ToppCell	facs-GAT-Fat-3m-Epithelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAO ODAD2 PROM1 PKHD1 CDH1 HYDIN	4.62e-05	181	158	6	5ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RGS9 KLHL29 PROM1 PKHD1 HYDIN L3MBTL4	4.76e-05	182	158	6	5e1b316599436740f1b30875f0ebd33c3edfb2b6
Drug	clobazam	GABRB2 GABRG3 CACNA1C CACNA1D PTCH1	1.52e-06	29	157	5	CID000002789
Disease	immunoglobulin G measurement	IGHG2 IGHG4	2.71e-05	2	154	2	EFO_0020465
Disease	Schizophrenia	GABRB2 CACNA1C PDE4D HLA-A SPTBN2 DAO RGS9 CHD4 PITPNM1 SLC26A8 NRXN2 NAV1 KMT2A SEPTIN7 CSMD1	6.35e-05	883	154	15	C0036341
Disease	exploratory eye movement measurement	CACNA1C AOC1 DAO PID1 CACNA2D3	6.75e-05	81	154	5	EFO_0007700
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1C CACNA1D	1.61e-04	4	154	2	DOID:0060173 (implicated_via_orthology)
Disease	neuroticism measurement, cognitive function measurement	CACNA1C KLHL2 PTPRU PTCH1 TG KLHL29 KIAA0825 LRFN5 NAV1 ELAVL4 CSMD1	2.00e-04	566	154	11	EFO_0007660, EFO_0008354
Disease	QRS duration, response to sulfonylurea	MDN1 LRFN5 CSMD1	2.29e-04	23	154	3	EFO_0005055, EFO_0007922
Disease	teratoma (is_implicated_in)	PGM3 NME1	2.68e-04	5	154	2	DOID:3307 (is_implicated_in)
Disease	wellbeing measurement	GABRG3 FNBP4 ODAD2 PTCH1 KLHL20 KLHL29 PTPRG LRFN5 PKHD1 AIPL1 KMT2A CACNA2D3	2.92e-04	692	154	12	EFO_0007869
Disease	Ischemic stroke	VWDE CNTN6 EPG5 KAT2B PTPRG ZNF516 POP1 FGA	3.16e-04	324	154	8	HP_0002140
Disease	blood manganese measurement	GABRG3 CSMD1 PID1	3.72e-04	27	154	3	EFO_0007581
Disease	response to gases and fumes exposure, forced expiratory volume	PDE4D AOC1	4.00e-04	6	154	2	EFO_0004314, EFO_0006994
Disease	nicotine dependence symptom count, depressive symptom measurement	AOC1 DAO KLHL29 LRP11	6.50e-04	75	154	4	EFO_0007006, EFO_0009262
Disease	Aqueductal Stenosis	MYH10 HYDIN	7.42e-04	8	154	2	C2936786
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1C CACNA1D CAPN1	8.77e-04	36	154	3	DOID:11723 (implicated_via_orthology)
Disease	neurodegenerative disease (implicated_via_orthology)	PTCH1 GGA3 PSMD6 MTMR11 TRAK2	1.01e-03	145	154	5	DOID:1289 (implicated_via_orthology)
Disease	nitric oxide exhalation measurement	CACNA1C ANO3 CACNA2D3	1.03e-03	38	154	3	EFO_0005536
Disease	resting heart rate	CACNA1C CACNA1D CEP85L KLHL42 CSMD1	1.14e-03	149	154	5	EFO_0004351
Disease	Fuchs endothelial corneal dystrophy	LAMC1 PTPRG	1.18e-03	10	154	2	Orphanet_98974
Disease	campesterol measurement	SLC3A1 ABCG8	1.44e-03	11	154	2	EFO_0020008
Disease	opioid dependence	AOC1 SPTBN2 DAO SFMBT2 NHSL1 CSMD1	1.58e-03	237	154	6	EFO_0005611
Disease	cognitive impairment measurement	CNTN6 PXDNL CSMD1	1.58e-03	44	154	3	EFO_0007998
Disease	Mood Disorders	GABRB2 CACNA1C CACNA1D DAO KAT2B	1.93e-03	168	154	5	C0525045
Disease	cannabis dependence measurement	PKHD1 CSMD1 ANO3	2.03e-03	48	154	3	EFO_0008457
Disease	squamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma	PKHD1 CSMD1	2.03e-03	13	154	2	EFO_0000707, EFO_0004193, EFO_0007932
Disease	cortical thickness	SPTBN2 LAMC1 BCL2L1 PTCH1 IDUA TG KLHL29 NHSL1 KIAA0825 LRP11 PKHD1 NAV1 KMT2A CACNA2D3	2.14e-03	1113	154	14	EFO_0004840
Disease	Retinitis Pigmentosa	CHM TUB PROM1 AIPL1	2.19e-03	104	154	4	C0035334
Disease	DNA methylation	GABRG3 SFMBT2 CNTN6 MDN1 PXDNL LRFN5 PKHD1 CSMD1 ANO3 CACNA2D3	2.42e-03	656	154	10	GO_0006306
Disease	attempted suicide	CDKN2AIP PROM1 CSMD1 ANO3 CACNA2D3	2.48e-03	178	154	5	EFO_0004321
Disease	Antihypertensive use measurement	CACNA1C CACNA1D INO80 KAT2B KIAA0825 PXDNL	2.75e-03	265	154	6	EFO_0009927
Disease	triacylglycerol 52:2 measurement	PTPRU TG CSMD1	3.00e-03	55	154	3	EFO_0010414
Disease	Intrahepatic cholestasis of pregnancy	ENPP7 ABCG8	3.10e-03	16	154	2	EFO_0009048
Disease	lysosomal storage disease (implicated_via_orthology)	HEXB GGA3	3.10e-03	16	154	2	DOID:3211 (implicated_via_orthology)
Disease	central nervous system disease (implicated_via_orthology)	SMARCA5 SMARCA1	3.10e-03	16	154	2	DOID:331 (implicated_via_orthology)
Disease	cognitive function measurement	GABRB2 GABRG3 CACNA1C CACNA1D KLHL2 DMXL2 PDE4D CEL ABCC5 ZSWIM6 PTCH1 KMT2D PKHD1 GALNTL5 HYDIN CACNA2D3	3.47e-03	1434	154	16	EFO_0008354
Disease	Antibody Deficiency Syndrome	CACNA1C EPG5	3.50e-03	17	154	2	C0003257
Disease	non-Hodgkin lymphoma (is_implicated_in)	RAD54B KMT2A	3.50e-03	17	154	2	DOID:0060060 (is_implicated_in)
Disease	bacteriemia	MAGI3 PTPRG	3.50e-03	17	154	2	EFO_0003033
Disease	Colorectal Carcinoma	SPTBN2 ZBTB8B ABCC5 LAMC1 PTPRU PROM1 CHD5 PKHD1 NME1 CDH1	3.91e-03	702	154	10	C0009402
Disease	coronary artery disease	CEL CDKN2AIP MAGI3 LAMC1 INO80 PTPRU RRBP1 TUB VWDE EPG5 ZC3H12D PKHD1 PID1 ABCG8	4.02e-03	1194	154	14	EFO_0001645
Disease	pancreatic ductal carcinoma (is_marker_for)	L1CAM NME1 IL4R	4.02e-03	61	154	3	DOID:3587 (is_marker_for)
Disease	acute kidney failure (biomarker_via_orthology)	CAPN1 BCL2L1 FGA	4.02e-03	61	154	3	DOID:3021 (biomarker_via_orthology)
Disease	post-traumatic stress disorder	GABRB2 VWDE KAT2B LRFN5 CSMD1	4.25e-03	202	154	5	EFO_0001358
Disease	prion disease	POP1 PXYLP1	4.37e-03	19	154	2	EFO_0004720
Disease	hydrocephalus (implicated_via_orthology)	L1CAM HYDIN	4.37e-03	19	154	2	DOID:10908 (implicated_via_orthology)
Disease	oral squamous cell carcinoma (is_marker_for)	BCL2L1 KMT2D CDH1	4.40e-03	63	154	3	DOID:0050866 (is_marker_for)
Disease	cortical surface area measurement	HEXB MYH10 ITCH LAMC1 PTCH1 IDUA TG KLHL29 NHSL1 MTMR11 KIAA0825 PKHD1 NAV1 PLEKHM3 PID1	4.64e-03	1345	154	15	EFO_0010736
Disease	tea consumption measurement	STAP2 PKHD1 ELAVL4 CSMD1	4.74e-03	129	154	4	EFO_0010091
Disease	breast carcinoma (is_marker_for)	BCL2L1 KMT2D NME1	5.02e-03	66	154	3	DOID:3459 (is_marker_for)
Disease	hepatocellular carcinoma (is_marker_for)	CYP26B1 CHD4 PTCH1 KAT2B CHD5 CDH1	5.11e-03	301	154	6	DOID:684 (is_marker_for)
Disease	Disorder of eye	RGS9 CHM PROM1 AIPL1 INVS	5.20e-03	212	154	5	C0015397

Protein segments in the cluster

Peptide	Gene	Start	Entry
DNQSLAEDEFVYWPS	PTPRG	1251	P23470
LEDNESSQQRHYPWL	EPG5	1976	Q9HCE0
TVQQWDALYTDLPNR	PGM3	436	O95394
VDAPSDYQRETWNLS	AIPL1	156	Q9NZN9
VNDYIAVWDGPDQNS	CSMD1	2196	Q96PZ7
IIYDSDWNPHNDIQA	CHD5	1116	Q8TDI0
DYEANDPWVQQFILN	COG4	641	Q9H9E3
PQNTITWEEYISAEN	ANKRD13C	416	Q8N6S4
ATYLNDHLEPWIQEN	BCL2L1	171	Q07817
DLNYQVDLASQVPWF	ABCG8	51	Q9H221
VYNLSPDSDESVLWQ	ELAVL4	306	P26378
SVTYNLAWDPQDNRL	DMXL2	111	Q8TDJ6
IQEHQDPNSYSWALL	DMXL2	2496	Q8TDJ6
QPTLEQTQYSWERQA	AOC1	551	P19801
SSEWNNVDPYERDQL	CAPN1	311	P07384
VYTESWAQDPSQENK	CEL	386	P19835
VVTQETNEYLLWNPS	CC2D2B	1216	Q6DHV5
APNDEDWAYSQQLSA	CCDC80	786	Q76M96
LTNLEYPRTESEWEN	ANO3	621	Q9BYT9
EYQENSDIVSDSPVW	CHM	61	P24386
ILYDIDWNPATDIQA	RAD54B	736	Q9Y620
TQQWPAEDTDYAIYL	RGS9	111	O75916
VIFYDSDWNPTVDQQ	INO80	1191	Q9ULG1
NPQEADWSQQTFDYL	DAO	61	P14920
ELDLSYNNLETIPWD	LRFN5	151	Q96NI6
ADTVIIYDSDWNPQS	HELLS	686	Q9NRZ9
IYDSDWNPQSDLQAQ	HELLS	691	Q9NRZ9
SNDLSDVQWYQQPSN	IL18RAP	76	O95256
NAVEVNTYWIDEPDV	MDN1	2501	Q9NU22
VQYEWALLQGDPSVD	LRP11	241	Q86VZ4
DWDINNPSSSNVIYD	MAGI3	1111	Q5TCQ9
EEQLWDFLYNIPVST	KIAA0825	876	Q8IV33
IVTLWDVNSQSPYHN	NEDD1	186	Q8NHV4
EVYSQNSPIWDQDFL	KAT2B	356	Q92831
ESWNCLNTVERYNPE	IVNS1ABP	521	Q9Y6Y0
LNTVERYNPENNTWT	IVNS1ABP	526	Q9Y6Y0
NTVEVYNLESNEWSP	IVNS1ABP	621	Q9Y6Y0
WNQDTPLNSEYDFAL	MTMR11	86	A4FU01
AWSSHPEAINVYQEA	CYP26B1	171	Q9NR63
GNAQIVDWPVVYSND	KCNH5	31	Q8NCM2
SEYLSQNPRVAAWVE	CDKN2AIP	6	Q9NXV6
QVEVDDENWIYRAQP	NHSL1	51	Q5SYE7
SPNIFAWVYREINDD	PID1	176	Q7Z2X4
ASQTSVYLQEWDIPF	KSR1	596	Q8IVT5
LEDNREWYQSTIPQS	PDE4D	701	Q08499
AWQYLGTTQAENEQE	PEX5	371	P50542
DPNQIWIYNEEHELV	GALNT11	516	Q8NCW6
IWEYEDDFQIQRSPN	NRSN1	41	Q8IZ57
NATLQVDSWPVNERY	NRXN2	1236	Q9P2S2
NQSSYTQWDLQPDTD	L1CAM	1071	P32004
WTEYLEATQTNAVPA	L3MBTL4	271	Q8NA19
ATNPSNRQEDWEYII	GGA3	16	Q9NZ52
VADQLWVPDTYFLND	GABRB2	111	P47870
LDLSYNNLEQLPWEA	LRFN3	161	Q9BTN0
QQEEYLPIWRETNET	ASIC4	231	Q96FT7
YDNTQLQLKAESPWE	PLEKHM3	281	Q6ZWE6
YLNTVEAYDPQTNEW	KLHL5	721	Q96PQ7
EAYDPQTNEWTQVAP	KLHL5	726	Q96PQ7
SVVNPASYHNVQEEW	RHOJ	101	Q9H4E5
LSFHNDDLYVQWENP	IL13RA1	236	P78552
DDLYVQWENPQNFIS	IL13RA1	241	P78552
AELAVSTFWPNEYQV	PTPRU	146	Q92729
TDYKLQQQDTWEVPF	MAP3K13	151	O43283
LTQDWESRVQAYEEP	POP1	711	Q99575
NWYSDADVPASARQE	ALPG	186	P10696
DPEFYNSLIWVKENN	ITCH	681	Q96J02
SNLDPFNQYTEDQIW	ABCC5	1286	O15440
SALNPHWEGNTVYQE	PXDNL	986	A1KZ92
LVNNYQPEVLWSDGD	FUCA2	216	Q9BTY2
PDEDQNSLALGWLQY	GASK1A	381	Q9UFP1
FWLVAEDQDNDPLTY	CDHR2	46	Q9BYE9
FDPSYRNDLNNWVAE	HYDIN	1126	Q4G0P3
HLTYAVNIWSENDPA	IL4R	156	P24394
VNIWSENDPADFRIY	IL4R	161	P24394
NTAERYEPETNQWTL	KLHL10	401	Q6JEL2
EVYNTESNQWTVIAP	KLHL10	451	Q6JEL2
AISSVERYDPQTNEW	KLHL20	331	Q9Y2M5
WVLQDPVYEDLLSEN	CASD1	206	Q96PB1
IASEHYNQPNWLTEV	CACNA1C	541	Q13936
EYEDSSSNQKWVLAP	GABRG3	26	Q99928
PSNQDLYWSEDDQEL	CCNDBP1	226	O95273
VWTEAYIDSTLPQAQ	CACNA2D3	451	Q8IZS8
QWYLDNVFPELEASV	GALNTL5	426	Q7Z4T8
AWNTEYDVQQAPQED	CEP350	856	Q5VT06
DSYSLAPWQQQQIED	CEP85L	316	Q5SZL2
AWTFNDNPLYVQEDN	CNTN6	156	Q9UQ52
LPHSQADQYVLSWDQ	IDUA	56	P35475
PEYWDQETRNVKAQS	HLA-A	81	P04439
NNSPYEIENGVVWVS	FGA	831	P02671
QDWNECLDTIAYEPQ	MBTPS2	291	O43462
YNAEQVLSWEPVALS	IFNGR2	41	P38484
PSLDHNYAQWQEREE	KMT2A	1796	Q03164
EQYNPATNEWIYVAD	KLHL3	461	Q9UH77
AYNFDNSPVLQEWVT	LAMC1	231	P11047
ISVEWESNGQPENNY	IGHG2	256	P01859
VSQEDPEVQFNWYVD	IGHG4	146	P01861
PTSQEEWEAEFQRYQ	COX15	111	Q7KZN9
FRWNYDQDVDTPNLD	ENPP7	41	Q6UWV6
WHIVDDQSFPYQSIT	HEXB	236	P07686
EAAYNWQASKPTVQE	BTBD2	91	Q9BX70
VIIYDSDWNPHNDIQ	CHD4	1141	Q14839
DTYPAWARVSNITDQ	SLC13A4	611	Q9UKG4
EAFVNEPNYTVWSDL	NPEPPS	641	P55786
SSEHYNQPDWLTQIQ	CACNA1D	541	Q01668
VDRAVIYNPATQADW	MYH10	16	P35580
ANWTIQYNDPTQESI	CDH1	636	P12830
TNRPDSKNWQYQETI	PSMD6	356	Q15008
DAAPTESLLNWQDYE	INVS	206	Q9Y283
DLWNNSIIPYLQEGA	NAV1	1761	Q8NEY1
WYATELNPAFNSIEV	TAS2R46	66	P59540
DYENQDVASSSWPVI	STAP2	321	Q9UGK3
ENSPYVHLLDANQWA	RMND5A	246	Q9H871
ADVVILYDSDWNPQV	SMARCA1	586	P28370
TQTNEVTWELPQYLA	FNBP4	236	Q8N3X1
ITHAPNLDNIELYWN	NDRG2	221	Q9UN36
PEELVDYTSCAQNWI	NME1	136	P15531
PATVQWLLDNYETAE	RFX1	436	P22670
QYEEVEEVWLPNNSS	SLC26A8	676	Q96RN1
QEASADLPSEYWQIQ	ODAD2	441	Q5T2S8
AWNYELPATNYETQD	PROM1	31	O43490
WVSNDPVAYAASQAN	PTCH1	926	Q13635
NDDTPNRQYWDEDLL	SCG2	576	P13521
WLPTNSDYHTVNVDV	SLC3A1	526	Q07837
LPNDWSADQLYLETT	PXYLP1	191	Q8TE99
VAPETNNYTFWIQAD	PKHD1	381	P08F94
EPVYNWRTVINSAAD	SPIC	61	Q8N5J4
SLYNWNGITDVNPEN	URB1	276	O60287
QDNPWVINLHEVYET	STK17A	116	Q9UEE5
ALETSLTPEQVYNWF	ANHX	171	E9PGG2
IENILSVQPYSQEWE	SLC7A6OS	211	Q96CW6
SVQPYSQEWELVNDD	SLC7A6OS	216	Q96CW6
ALQVEEESWNAYPYT	PITPNM1	81	O00562
LFLYENQDWTQSPHQ	TRAK2	61	O60296
EDFLWNNYIPDSIQI	VWDE	401	Q8N2E2
RVAELDPVNSYQAWQ	ZNF516	406	Q92618
EQSLYWLAIQQLPTD	ZMYND19	121	Q96E35
YNQDTHPAINDVLWA	ZSWIM5	1031	Q9P217
LPELSVLAQQNYTEW	RRBP1	1071	Q9P2E9
QLPSDWIQVAELYQS	TEP1	331	Q99973
QGQYSDINNRWDLPD	SPTBN2	16	O15020
VDNSNCWQPVIDYID	SEPTIN7	121	Q16181
WTQNTPNEYIKTLAD	SOGA1	731	O94964
EVANKNNPDTYWVAT	SFMBT2	81	Q5VUG0
EEWEFLNPAQQSLYR	ZNF682	16	O95780
SNDNYRDLQSENPEW	ZC3H12D	196	A2A288
VAVYFTQNQWASLDP	ZNF621	16	Q6ZSS3
YNQDTHPAINDVLWA	ZSWIM6	1061	Q9HCJ5
QSYPDEVWQTDDLIE	ZNF12	76	P17014
GDQAWQLRYASQEPE	ZNF142	601	P52746
ADVVILYDSDWNPQV	SMARCA5	571	O60264
EPDNAEAWNNLSTSY	TTC27	591	Q6P3X3
AQDLWPEQSIKDSYQ	ZNF486	91	Q96H40
EVPDGLDSQNSNYWV	PTPRH	51	Q9HD43
WVSANIFEYQVDAQP	TG	16	P01266
WKQLDPAQSNLYNDV	ZFP37	46	Q9Y6Q3
PWLQYNEVNESSSDE	PJA2	501	O43164
LYEQVVFTNPSWDAE	TFR2	546	Q9UP52
QNKTPVWNDDTQSYV	TUB	426	P50607
NNEFWEANRDIYLSP	ZRSR2	336	Q15696
TWENELPVSKYANNL	USP13	181	Q92995
WETANNRLHQEYVPS	WDR43	41	Q15061
SQEKSDTDNDWPIYV	ZBTB8B	451	Q8NAP8
ERYDTITNQWEAVAP	KLHL29	701	Q96CT2
VSNVECYNPEQDAWN	KLHL42	311	Q9P2K6
DSYDPVKDQWTSVAN	KLHL2	371	O95198
AELNPNSEWFENYSL	KMT2D	331	O14686
PAEEENSLNEEWYVS	LCP2	411	Q13094
RPESSAHVQELYQEW	NARF	411	Q9UHQ1