Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A1 COL4A2 COL4A4 COL27A1 COLQ

3.16e-0646995GO:0030020
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL4A1 COL4A2 COL4A4 HSPG2 COL27A1 EMID1 COLQ

4.21e-05188997GO:0005201
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

ZNF628 IRF5 POU5F1 POU5F1B RAX PHOX2A KMT2D NFATC3 LEF1 TP73

4.62e-045609910GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

ZNF628 IRF5 POU5F1 POU5F1B RAX PHOX2A KMT2D NFATC3 LEF1 TP73

5.02e-045669910GO:0001216
GeneOntologyMolecularFunctionPOU domain binding

POU5F1 POU5F1B

5.03e-047992GO:0070974
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF628 ZBTB4 ZNF316 ZBTB9 ZNF696 IRF5 POU5F1 POU5F1B RAX HIVEP3 PHOX2A KMT2D FOXD4L1 NFATC3 ZFHX2 LEF1 TP73

5.42e-0414129917GO:0000981
GeneOntologyMolecularFunctionhistone H3K4 monomethyltransferase activity

KMT2B KMT2D

6.68e-048992GO:0140945
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CALHM1 KCNH3 KCNG2 KCNH2 CACNA1H

9.63e-04152995GO:0022843
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

KMT2B KMT2D

1.07e-0310992GO:0140999
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF628 ZBTB4 ZNF316 ZBTB9 IRF5 POU5F1 POU5F1B RAX HIVEP3 PHOX2A FOXD4L1 NFATC3 ZFHX2 LEF1 TP73

1.17e-0312449915GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF628 ZBTB4 ZNF316 ZBTB9 IRF5 POU5F1 POU5F1B RAX HIVEP3 PHOX2A FOXD4L1 NFATC3 ZFHX2 LEF1 TP73

1.45e-0312719915GO:0000987
GeneOntologyMolecularFunctionRNA polymerase II intronic transcription regulatory region sequence-specific DNA binding

POU5F1 POU5F1B

1.83e-0313992GO:0001162
GeneOntologyMolecularFunctionMAP-kinase scaffold activity

MAPK8IP1 SH3RF1

1.83e-0313992GO:0005078
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF628 ZBTB4 ZNF316 ZBTB9 ZNF696 IRF5 POU5F1 POU5F1B RAX HIVEP3 PHOX2A FOXD4L1 NFATC3 ZFHX2 LEF1 TP73

2.13e-0314599916GO:0000977
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CALHM1 KCNH3 KCNG2 KCNH2 CACNA1H

2.13e-03182995GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CALHM1 KCNH3 KCNG2 KCNH2 CACNA1H

2.24e-03184995GO:0022832
GeneOntologyBiologicalProcessregulation of calcium ion-dependent exocytosis

SYT3 POU5F1 POU5F1B CACNA1H

5.67e-0545964GO:0017158
GeneOntologyBiologicalProcesstrophectodermal cell fate commitment

POU5F1 POU5F1B

6.41e-053962GO:0001830
GeneOntologyBiologicalProcesschordate embryonic development

HSPG2 POU5F1 POU5F1B ADD1 KMT2D MEGF8 TIE1 MTHFR RBM46 DHX35 MYO18B EPN1 LEF1 NOS3

7.53e-059069614GO:0043009
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

HSPG2 POU5F1 POU5F1B ADD1 KMT2D MEGF8 TIE1 MTHFR RBM46 DHX35 MYO18B EPN1 LEF1 NOS3

9.83e-059299614GO:0009792
GeneOntologyBiologicalProcessin utero embryonic development

POU5F1 POU5F1B ADD1 KMT2D TIE1 RBM46 DHX35 MYO18B EPN1 LEF1 NOS3

1.02e-045969611GO:0001701
GeneOntologyBiologicalProcesscerebrospinal fluid secretion

CELSR2 TP73

1.28e-044962GO:0033326
GeneOntologyCellularComponentcollagen type IV trimer

COL4A1 COL4A2 COL4A4

1.98e-066983GO:0005587
GeneOntologyCellularComponentcomplex of collagen trimers

COL4A1 COL4A2 COL4A4 COL27A1

2.56e-0621984GO:0098644
GeneOntologyCellularComponentcollagen trimer

COL4A1 COL4A2 COL4A4 COL27A1 EMID1 COLQ

3.61e-0688986GO:0005581
GeneOntologyCellularComponentbasement membrane collagen trimer

COL4A1 COL4A2 COL4A4

5.50e-068983GO:0098651
GeneOntologyCellularComponentnetwork-forming collagen trimer

COL4A1 COL4A2 COL4A4

5.50e-068983GO:0098642
GeneOntologyCellularComponentcollagen network

COL4A1 COL4A2 COL4A4

5.50e-068983GO:0098645
GeneOntologyCellularComponentbasement membrane

COL4A1 COL4A2 COL4A4 HSPG2 COLQ

2.75e-04122985GO:0005604
GeneOntologyCellularComponentcollagen-containing extracellular matrix

COL4A1 COL4A2 COL4A4 HSPG2 COL27A1 EMID1 ADAM11 COLQ NCAN

8.62e-04530989GO:0062023
GeneOntologyCellularComponentsynaptic membrane

SYT3 APBB1 LRRC4B ADAM11 SHISA7 PDLIM4 CACNA1H IGSF9B EPN1

1.67e-03583989GO:0097060
DomainC4

COL4A1 COL4A2 COL4A4

2.36e-066933SM00111
Domain-

COL4A1 COL4A2 COL4A4

2.36e-0669332.170.240.10
DomainCollagen_VI_NC

COL4A1 COL4A2 COL4A4

2.36e-066933IPR001442
DomainC4

COL4A1 COL4A2 COL4A4

2.36e-066933PF01413
DomainNC1_IV

COL4A1 COL4A2 COL4A4

2.36e-066933PS51403
DomainCollagen

COL4A1 COL4A2 COL4A4 COL27A1 EMID1 COLQ

4.13e-0685936IPR008160
DomainCollagen

COL4A1 COL4A2 COL4A4 COL27A1 EMID1 COLQ

4.13e-0685936PF01391
DomainM_domain

TNRC6C TNRC6A

2.45e-052932PF12938
DomainGW182_M_dom

TNRC6C TNRC6A

2.45e-052932IPR026805
DomainAgo_hook

TNRC6C TNRC6A

7.33e-053932PF10427
DomainTNRC6_PABC-bd

TNRC6C TNRC6A

7.33e-053932IPR032226
DomainArgonaute_hook_dom

TNRC6C TNRC6A

7.33e-053932IPR019486
DomainTNRC6-PABC_bdg

TNRC6C TNRC6A

7.33e-053932PF16608
DomainPOU_dom_5

POU5F1 POU5F1B

7.33e-053932IPR015585
DomainFYrich_C

KMT2B KMT2D

2.43e-045932IPR003889
DomainFYrich_N

KMT2B KMT2D

2.43e-045932IPR003888
DomainFYRC

KMT2B KMT2D

2.43e-045932SM00542
DomainFYRN

KMT2B KMT2D

2.43e-045932SM00541
DomainFYRN

KMT2B KMT2D

2.43e-045932PF05964
DomainFYRC

KMT2B KMT2D

2.43e-045932PF05965
DomainFYRC

KMT2B KMT2D

2.43e-045932PS51543
DomainFYRN

KMT2B KMT2D

2.43e-045932PS51542
DomainEGF_LAM_2

HSPG2 CELSR2 MEGF8

4.40e-0430933PS50027
DomainEGF_LAM_1

HSPG2 CELSR2 MEGF8

4.40e-0430933PS01248
DomainLaminin_EGF

HSPG2 CELSR2 MEGF8

6.97e-0435933PF00053
DomainEGF_Lam

HSPG2 CELSR2 MEGF8

6.97e-0435933SM00180
DomainLAM_G_DOMAIN

HSPG2 COL27A1 CELSR2

8.89e-0438933PS50025
DomainLaminin_EGF

HSPG2 CELSR2 MEGF8

8.89e-0438933IPR002049
DomainPAS_9

KCNH3 KCNH2

1.08e-0310932PF13426
DomainEGF_3

HSPG2 ADAM11 CELSR2 MEGF8 TIE1 NCAN

1.14e-03235936PS50026
DomainEGF

HSPG2 ADAM11 CELSR2 MEGF8 TIE1 NCAN

1.14e-03235936SM00181
DomainEGF-like_dom

HSPG2 ADAM11 CELSR2 MEGF8 TIE1 NCAN

1.53e-03249936IPR000742
DomainEGF_1

HSPG2 ADAM11 CELSR2 MEGF8 TIE1 NCAN

1.73e-03255936PS00022
DomainEGF-like_CS

HSPG2 ADAM11 CELSR2 MEGF8 TIE1 NCAN

1.94e-03261936IPR013032
DomainCTDL_fold

COL4A1 COL4A2 COL4A4 NCAN

2.01e-03107934IPR016187
DomainEGF_2

HSPG2 ADAM11 CELSR2 MEGF8 TIE1 NCAN

2.10e-03265936PS01186
DomainK_chnl_volt-dep_EAG/ELK/ERG

KCNH3 KCNH2

2.15e-0314932IPR003938
DomainHMG_box

KMT2D MEIOSIN LEF1

2.34e-0353933PF00505
DomainHomeobox_CS

POU5F1 POU5F1B RAX PHOX2A ZFHX2

2.38e-03186935IPR017970
DomainHMG

KMT2D MEIOSIN LEF1

2.47e-0354933SM00398
DomainIon_trans_dom

KCNH3 KCNG2 KCNH2 CACNA1H

2.53e-03114934IPR005821
DomainIon_trans

KCNH3 KCNG2 KCNH2 CACNA1H

2.53e-03114934PF00520
Domain-

KMT2D MEIOSIN LEF1

2.60e-03559331.10.30.10
DomainPOU

POU5F1 POU5F1B

2.81e-0316932SM00352
DomainPost-SET_dom

KMT2B KMT2D

2.81e-0316932IPR003616
DomainPOU_2

POU5F1 POU5F1B

2.81e-0316932PS00465
DomainPOU_dom

POU5F1 POU5F1B

2.81e-0316932IPR000327
DomainPOU_3

POU5F1 POU5F1B

2.81e-0316932PS51179
DomainPostSET

KMT2B KMT2D

2.81e-0316932SM00508
DomainPou

POU5F1 POU5F1B

2.81e-0316932PF00157
DomainPOU_1

POU5F1 POU5F1B

2.81e-0316932PS00035
DomainPOST_SET

KMT2B KMT2D

2.81e-0316932PS50868
DomainLaminin_G

HSPG2 COL27A1 CELSR2

3.03e-0358933IPR001791
DomainPOU

POU5F1 POU5F1B

3.18e-0317932IPR013847
DomainEGF_CA

HSPG2 CELSR2 MEGF8 NCAN

3.23e-03122934SM00179
DomainEGF-like_Ca-bd_dom

HSPG2 CELSR2 MEGF8 NCAN

3.43e-03124934IPR001881
DomainEGF

HSPG2 CELSR2 TIE1 NCAN

3.63e-03126934PF00008
DomainHMG_box_dom

KMT2D MEIOSIN LEF1

4.18e-0365933IPR009071
Domainzf-MYND

ZMYND15 USP19

4.84e-0321932PF01753
DomainEPHD

KMT2B KMT2D

5.31e-0322932PS51805
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A1 COL4A2 COL4A4 NCAN CACNA1H PRNP

3.84e-0842666M7169
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL4A1 COL4A2 COL4A4 NCAN CACNA1H PRNP

4.60e-0763666M11187
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A1 COL4A2 COL4A4 HSPG2

1.10e-0530664M27216
PathwayBIOCARTA_NPP1_PATHWAY

COL4A1 COL4A2 COL4A4

1.15e-0510663M22040
PathwayBIOCARTA_NPP1_PATHWAY

COL4A1 COL4A2 COL4A4

1.15e-0510663MM1560
PathwayBIOCARTA_VITCB_PATHWAY

COL4A1 COL4A2 COL4A4

1.57e-0511663M15422
PathwayBIOCARTA_VITCB_PATHWAY

COL4A1 COL4A2 COL4A4

2.09e-0512663MM1526
PathwayBIOCARTA_ACE2_PATHWAY

COL4A1 COL4A2 COL4A4

2.71e-0513663MM1347
PathwayBIOCARTA_ACE2_PATHWAY

COL4A1 COL4A2 COL4A4

2.71e-0513663M12950
PathwayREACTOME_ECM_PROTEOGLYCANS

COL4A1 COL4A2 COL4A4 HSPG2 NCAN

2.76e-0576665M27219
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A1 COL4A2 COL4A4

3.44e-0514663MM1458
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A1 COL4A2 COL4A4

3.44e-0514663M6487
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

COL4A1 COL4A2 COL4A4

4.28e-0515663M27161
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A1 COL4A2 COL4A4

4.28e-0515663MM14922
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A1 COL4A2 COL4A4 COL27A1

5.17e-0544664M27812
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A1 COL4A2 COL4A4

7.61e-0518663M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A1 COL4A2 COL4A4

7.61e-0518663MM14882
PathwayBIOCARTA_AMI_PATHWAY

COL4A1 COL4A2 COL4A4

1.06e-0420663M15394
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A1 COL4A2 COL4A4

1.06e-0420663MM15061
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A1 COL4A2 COL4A4

1.62e-0423663M15997
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A1 COL4A2 COL4A4

1.62e-0423663MM1427
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A1 COL4A2 COL4A4 HSPG2

1.64e-0459664M27218
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A1 COL4A2 COL4A4 COL27A1

1.87e-0461664M27103
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A1 COL4A2 COL4A4 COL27A1

2.69e-0467664M26999
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A1 COL4A2 COL4A4

4.41e-0432663MM14924
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

TNRC6C TNRC6A

4.47e-047662M46421
PathwayWP_MIRNAS_AND_TFS_IN_IPS_CELL_GENERATION

POU5F1 POU5F1B

5.94e-048662MM15855
PathwayKEGG_ECM_RECEPTOR_INTERACTION

COL4A1 COL4A2 COL4A4 HSPG2

6.38e-0484664M7098
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A1 COL4A2 COL4A4 HSPG2

6.68e-0485664M16441
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL4A1 COL4A2 COL4A4

7.36e-0438663MM14969
PathwayREACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION

TNRC6C TNRC6A

7.61e-049662M27810
PathwayREACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION

TNRC6C TNRC6A

7.61e-049662M46436
PathwayREACTOME_COLLAGEN_FORMATION

COL4A1 COL4A2 COL4A4 COL27A1

8.28e-0490664M631
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX

TNRC6C TNRC6A LEF1

9.20e-0441663M29748
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A1 COL4A2 COL4A4

9.20e-0441663MM15538
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNH3 KCNG2 KCNH2

9.20e-0441663MM14546
PathwayREACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS

TNRC6C TNRC6A

9.48e-0410662M48013
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

KMT2B TNRC6C KMT2D TNRC6A

1.05e-0396664M27792
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNH3 KCNG2 KCNH2

1.06e-0343663M1056
PathwayREACTOME_REGULATION_OF_NPAS4_GENE_EXPRESSION

TNRC6C TNRC6A

1.63e-0313662M46434
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A1 COL4A2 COL4A4

1.64e-0350663MM14796
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A1 COL4A2 COL4A4

1.94e-0353663MM14566
PathwayREACTOME_SIGNALING_BY_PDGF

COL4A1 COL4A2 COL4A4

2.39e-0357663MM14713
PathwayREACTOME_SIGNALING_BY_PDGF

COL4A1 COL4A2 COL4A4

2.52e-0358663M2049
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A1 COL4A2 COL4A4 HSPG2 COL27A1 NCAN

2.75e-03300666M610
PathwayREACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY

TNRC6C TNRC6A

2.81e-0317662M27788
PathwayREACTOME_GERM_LAYER_FORMATION_AT_GASTRULATION

POU5F1 LEF1

2.81e-0317662M45017
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A1 COL4A2 COL4A4

2.91e-0361663MM14637
PathwayREACTOME_CA2_PATHWAY

TNRC6C TNRC6A LEF1

3.04e-0362663M27321
PathwayWP_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION

IRF5 KCNH2 LEF1

3.19e-0363663M39366
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HSPG2 KMT2B SH3RF1 ZNF628 EMID1 ZBTB4 ZNF316 HECTD4 IRF5 TNRC6C KCNH3 HIVEP3 KMT2D SCAP CELSR2 MEGF8 MTHFR KCNH2 NEK8 CACNA1H D2HGDH PRRT4

6.28e-1311051002235748872
Pubmed

Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.

COL4A1 COL4A2 COL4A4 HSPG2

1.33e-081010049136074
Pubmed

Binding of mouse and human fibulin-2 to extracellular matrix ligands.

COL4A1 COL4A2 COL4A4 HSPG2

2.09e-081110047500359
Pubmed

Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.

COL4A1 COL4A2 COL4A4 HSPG2

3.13e-0812100416024816
Pubmed

Nature and the multiple functions of the 67-kD elastin-/laminin binding protein.

COL4A1 COL4A2 COL4A4

9.21e-08410037827955
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

COL4A1 COL4A2 COL4A4 HSPG2

1.14e-0716100415878328
Pubmed

Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally but show severe age-onset cataract formation and disruption of the lens.

COL4A1 COL4A2 HSPG2

2.30e-07510039524110
Pubmed

In vitro interactions of oxidatively modified LDL with type I, II, III, IV, and V collagen, laminin, fibronectin, and poly-D-lysine.

COL4A1 COL4A2 COL4A4

2.30e-07510039409248
Pubmed

Genetic effects on carotid intima-media thickness: systematic assessment and meta-analyses of candidate gene polymorphisms studied in more than 5000 subjects.

ADD1 MTHFR NOS3

2.30e-075100320160191
Pubmed

A census of human transcription factors: function, expression and evolution.

ZBTB4 IRF5 POU5F1 POU5F1B ZC3H3 RAX HIVEP3 PHOX2A KMT2D FOXD4L1 NFATC3 ZFHX2 LEF1 TP73

3.42e-079081001419274049
Pubmed

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.

COL4A1 COL4A2 COL4A4 HSPG2

3.71e-0721100427856617
Pubmed

Extracellular matrix of the human optic nerve head.

COL4A1 COL4A2 COL4A4

4.58e-07610032426947
Pubmed

Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.

COL4A1 COL4A2 COL4A4

4.58e-076100310534397
Pubmed

Developmental distribution of collagen IV isoforms and relevance to ocular diseases.

COL4A1 COL4A2 COL4A4

4.58e-076100319275937
Pubmed

Distribution of basement membrane proteins in normal and fibrotic human liver: collagen type IV, laminin, and fibronectin.

COL4A1 COL4A2 COL4A4

4.58e-07610036988303
Pubmed

Stimulation of extracellular matrix components in the normal brain by invading glioma cells.

COL4A1 COL4A2 COL4A4

4.58e-07610039506531
Pubmed

HIV-1 gp160 protein-macrophage interactions modulate mesangial cell proliferation and matrix synthesis.

COL4A1 COL4A2 COL4A4

4.58e-07610037495302
Pubmed

Angiogenesis and collagen type IV expression in different endothelial cell culture systems.

COL4A1 COL4A2 COL4A4

4.58e-076100323551189
Pubmed

Monoclonal antibody to human basement membrane collagen type IV.

COL4A1 COL4A2 COL4A4

4.58e-07610036811420
Pubmed

Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas.

COL4A1 COL4A2 COL4A4

4.58e-07610036389236
Pubmed

Collagen IV in the developing lens capsule.

COL4A1 COL4A2 COL4A4

4.58e-076100312225806
Pubmed

A tumor derived motility factor that stimulates cell migration on extracellular matrix.

COL4A1 COL4A2 COL4A4

4.58e-07610039673377
Pubmed

Localization of type IV collagen a 1 to a 6 chains in basement membrane during mouse molar germ development.

COL4A1 COL4A2 COL4A4

4.58e-076100311732842
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

COL4A1 COL4A2 COL4A4 HSPG2 COL27A1 EMID1 COLQ

5.71e-07167100722159717
Pubmed

Rbm46 regulates trophectoderm differentiation by stabilizing Cdx2 mRNA in early mouse embryos.

POU5F1 POU5F1B RBM46

8.01e-077100325397698
Pubmed

Regulation of protease nexin-1 target protease specificity by collagen type IV.

COL4A1 COL4A2 COL4A4

8.01e-07710038006028
Pubmed

Corneal cell proteins and ocular surface pathology.

COL4A1 COL4A2 COL4A4

8.01e-077100310416788
Pubmed

Hypoplastic basement membrane of the lens anlage in the inheritable lens aplastic mouse (lap mouse).

COL4A1 COL4A2 COL4A4

8.01e-077100310716744
Pubmed

Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development.

COL4A1 COL4A2 COL4A4

8.01e-07710037521231
Pubmed

Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo.

COL4A1 COL4A2 COL4A4

8.01e-077100310639489
Pubmed

Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M.

COL4A1 COL4A2 COL4A4

8.01e-077100311711546
Pubmed

Purification, partial characterization of rat kidney hyaluronic acid binding protein and its localization on the cell surface.

COL4A1 COL4A2 COL4A4

8.01e-07710031724753
Pubmed

Premature aggregation of type IV collagen and early lethality in lysyl hydroxylase 3 null mice.

COL4A1 COL4A2 HSPG2

8.01e-077100315377789
Pubmed

Amniotic ectoderm expansion in mouse occurs via distinct modes and requires SMAD5-mediated signalling.

COL4A1 POU5F1 POU5F1B

1.28e-068100329884675
Pubmed

Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.

COL4A1 COL4A2 COL4A4

1.28e-06810033997552
Pubmed

Risks of human conotruncal heart defects associated with 32 single nucleotide polymorphisms of selected cardiovascular disease-related genes.

ADD1 MTHFR NOS3

1.28e-068100316100725
Pubmed

Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium.

COL4A1 COL4A2 COL4A4

1.28e-068100329422532
Pubmed

Mice develop normally without tenascin.

COL4A1 COL4A4 HSPG2

1.28e-06810031383086
Pubmed

Molecular properties of wild-type and mutant betaIG-H3 proteins.

COL4A1 COL4A2 COL4A4

1.28e-068100311867580
Pubmed

Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth.

COL4A1 COL4A2 COL4A4

1.28e-068100310382266
Pubmed

Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis.

COL4A1 COL4A2 COL4A4

1.91e-06910038562707
Pubmed

Characterization of high affinity binding between laminin and the acute-phase protein, serum amyloid A.

COL4A1 COL4A2 COL4A4

1.91e-06910038995276
Pubmed

Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.

COL4A1 COL4A2 COL4A4

1.91e-069100312101409
Pubmed

Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors.

POU5F1 POU5F1B KMT2D

1.91e-069100326691508
Pubmed

Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome.

COL4A1 COL4A2 COL4A4

1.91e-069100310880400
Pubmed

MMP-9 from TNF alpha-stimulated keratinocytes binds to cell membranes and type I collagen: a cause for extended matrix degradation in inflammation?

COL4A1 COL4A2 COL4A4

1.91e-06910039878537
Pubmed

Laminin γ1 C-terminal Glu to Gln mutation induces early postimplantation lethality.

HSPG2 POU5F1 POU5F1B

1.91e-069100330456378
Pubmed

Stress-inducible phosphoprotein 1 has unique cochaperone activity during development and regulates cellular response to ischemia via the prion protein.

POU5F1 POU5F1B PRNP

1.91e-069100323729591
Pubmed

Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.

COL4A1 COL4A2 COL4A4

2.73e-061010039415455
Pubmed

Generation of a conditionally null allele of the laminin alpha1 gene.

COL4A1 COL4A2 HSPG2

2.73e-0610100316100707
Pubmed

Large-scale identification of genes implicated in kidney glomerulus development and function.

COL4A1 COL4A2 COL4A4 HSPG2

2.79e-0634100416498405
Pubmed

Basement membrane remodelling regulates mouse embryogenesis.

HSPG2 POU5F1 POU5F1B

3.74e-0611100332523119
Pubmed

Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.

COL4A1 COL4A2 COL4A4

3.74e-0611100314998921
Pubmed

Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.

COL4A1 COL4A2 COL4A4

3.74e-061110039731539
Pubmed

Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice.

COL4A1 COL4A2 COL4A4

4.98e-061210038918877
Pubmed

Basement membrane fragility underlies embryonic lethality in fukutin-null mice.

COL4A1 COL4A2 COL4A4

4.98e-0612100315837576
Pubmed

Matrilin-2 interacts with itself and with other extracellular matrix proteins.

COL4A1 COL4A2 COL4A4

4.98e-0612100312180907
Pubmed

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

COL4A1 COL4A2 COL4A4 TIE1

5.43e-0640100427068110
Pubmed

ECM-integrin signalling instructs cellular position sensing to pattern the early mouse embryo.

COL4A1 POU5F1 POU5F1B

6.46e-0613100334908109
Pubmed

Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.

COL4A1 COL4A2 COL4A4

6.46e-061310039833687
Pubmed

Prevalence of COL4A1 and COL4A2 mutations in severe fetal multifocal hemorrhagic and/or ischemic cerebral lesions.

COL4A1 COL4A2

8.18e-062100232515830
Pubmed

Sequence variants in COL4A1 and COL4A2 genes in Ecuadorian families with keratoconus.

COL4A1 COL4A2

8.18e-062100221527998
Pubmed

Identification of mouse blastocyst genes that are downregulated by double-stranded RNA-mediated knockdown of Oct-4 expression.

POU5F1 POU5F1B

8.18e-062100215685634
Pubmed

Nuclear and chromatin reorganization in the MHC-Oct3/4 locus at developmental phases of embryonic stem cell differentiation.

POU5F1 POU5F1B

8.18e-062100216950240
Pubmed

Maternal Oct-4 is a potential key regulator of the developmental competence of mouse oocytes.

POU5F1 POU5F1B

8.18e-062100218837968
Pubmed

Cruciform Formable Sequences within Pou5f1 Enhancer Are Indispensable for Mouse ES Cell Integrity.

POU5F1 POU5F1B

8.18e-062100233810223
Pubmed

Phosphorylation of Threonine343 Is Crucial for OCT4 Interaction with SOX2 in the Maintenance of Mouse Embryonic Stem Cell Pluripotency.

POU5F1 POU5F1B

8.18e-062100228988986
Pubmed

Abnormal DNA methylation of the Oct-4 enhancer region in cloned mouse embryos.

POU5F1 POU5F1B

8.18e-062100218932201
Pubmed

Is there relation between COL4A1/A2 mutations and antenatally detected fetal intraventricular hemorrhage?

COL4A1 COL4A2

8.18e-062100224317722
Pubmed

A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo.

POU5F1 POU5F1B

8.18e-06210021972777
Pubmed

Mouse Oct-3 maps between the tcl12 embryonic lethal gene and the Qa gene in the H-2 complex.

POU5F1 POU5F1B

8.18e-06210021680810
Pubmed

Heterogeneous DNA methylation status of the regulatory element of the mouse Oct4 gene in adult somatic cell population.

POU5F1 POU5F1B

8.18e-062100215996113
Pubmed

Oct4 transcription factor in conjunction with valproic acid accelerates myelin repair in demyelinated optic chiasm in mice.

POU5F1 POU5F1B

8.18e-062100226804242
Pubmed

Conserved, developmentally regulated mechanism couples chromosomal looping and heterochromatin barrier activity at the homeobox gene A locus.

POU5F1 POU5F1B

8.18e-062100221502535
Pubmed

Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells.

POU5F1 POU5F1B

8.18e-062100211839818
Pubmed

Head-to-head arrangement of murine type IV collagen genes.

COL4A1 COL4A2

8.18e-06210023198626
Pubmed

Intracerebral hemorrhage in a neonate with an intragenic COL4A2 duplication.

COL4A1 COL4A2

8.18e-062100233247988
Pubmed

A novel Oct4/Pou5f1-like non-coding RNA controls neural maturation and mediates developmental effects of ethanol.

POU5F1 POU5F1B

8.18e-062100233221301
Pubmed

Developmental fate of embryonic germ cells (EGCs), in vivo and in vitro.

POU5F1 POU5F1B

8.18e-062100212641567
Pubmed

A nontranscriptional role for Oct4 in the regulation of mitotic entry.

POU5F1 POU5F1B

8.18e-062100225324523
Pubmed

A novel multiplex PCR-RFLP method for simultaneous detection of the MTHFR 677 C > T, eNOS +894 G > T and - eNOS -786 T > C variants among Malaysian Malays.

MTHFR NOS3

8.18e-062100222594584
Pubmed

Novel variants of Oct-3/4 gene expressed in mouse somatic cells.

POU5F1 POU5F1B

8.18e-062100218765667
Pubmed

Oct4 dependence of chromatin structure within the extended Nanog locus in ES cells.

POU5F1 POU5F1B

8.18e-062100218283123
Pubmed

Mechanisms of OCT4 on 3,5,3'-Tri-iodothyronine and FSH-induced Granulosa Cell Development in Female Mice.

POU5F1 POU5F1B

8.18e-062100234463738
Pubmed

Differential expression of Oct3/4 in human breast cancer and normal tissues.

POU5F1 POU5F1B

8.18e-062100229620155
Pubmed

Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4.

POU5F1 POU5F1B

8.18e-062100227346346
Pubmed

Replication of Top Loci From COL4A1/2 Associated With White Matter Hyperintensity Burden in Patients With Ischemic Stroke.

COL4A1 COL4A2

8.18e-062100233148145
Pubmed

The genes for the alpha 1(IV) and alpha 2(IV) chains of human basement membrane collagen type IV are arranged head-to-head and separated by a bidirectional promoter of unique structure.

COL4A1 COL4A2

8.18e-06210022846280
Pubmed

Genome-wide meta-analysis identifies 3 novel loci associated with stroke.

COL4A1 NOS3

8.18e-062100230383316
Pubmed

Critical POU domain residues confer Oct4 uniqueness in somatic cell reprogramming.

POU5F1 POU5F1B

8.18e-062100226877091
Pubmed

The embryonic Octamer factor 3/4 displays distinct DNA binding specificity from those of other Octamer factors.

POU5F1 POU5F1B

8.18e-062100212615074
Pubmed

Effect of ectopic expression of homeoprotein EGAM1C on the cell morphology, growth, and differentiation in a mouse embryonic stem cell line, MG1.19 cells.

POU5F1 POU5F1B

8.18e-062100222367590
Pubmed

Genotype-phenotype correlations in pathology caused by collagen type IV alpha 1 and 2 mutations.

COL4A1 COL4A2

8.18e-062100227794444
Pubmed

Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4).

KMT2B KMT2D

8.18e-062100235640156
Pubmed

Methylentetrahydrofolate reductase and nitric oxide synthase polymorphism in patients with atherosclerosis and diabetes.

MTHFR NOS3

8.18e-062100219330466
Pubmed

Targeted disruption of organic cation transporter 3 (Oct3) ameliorates ischemic brain damage through modulating histamine and regulatory T cells.

POU5F1 POU5F1B

8.18e-062100222739622
Pubmed

Oct-4: more than just a POUerful marker of the mammalian germline?

POU5F1 POU5F1B

8.18e-06210029524569
Pubmed

Transient pairing of homologous Oct4 alleles accompanies the onset of embryonic stem cell differentiation.

POU5F1 POU5F1B

8.18e-062100225748933
Pubmed

Expression pattern of Oct-4 in preimplantation embryos of different species.

POU5F1 POU5F1B

8.18e-062100211090438
Pubmed

A saturating mutagenesis CRISPR-Cas9-mediated functional genomic screen identifies cis- and trans-regulatory elements of Oct4 in murine ESCs.

POU5F1 POU5F1B

8.18e-062100232994224
InteractionFBLN2 interactions

COL4A1 COL4A2 COL4A4 HSPG2 ZNF628 ZNF316 ZNF696

2.76e-0866967int:FBLN2
InteractionTOP3B interactions

HSPG2 KMT2B SH3RF1 ZNF628 SAMD4B EMID1 ZBTB4 ZNF316 HECTD4 IRF5 TNRC6C KCNH3 HIVEP3 KMT2D SCAP CELSR2 MEGF8 MTHFR KCNH2 NEK8 CACNA1H D2HGDH PRRT4

2.87e-0714709623int:TOP3B
CytobandEnsembl 112 genes in cytogenetic band chr19q13

NAT14 KMT2B ZNF628 SYT3 GGN SAMD4B LRRC4B SHISA7 SPRED3 ITPKC MEGF8 MEIOSIN BRSK1 EPN1

3.25e-07119210014chr19q13
Cytoband19q13.42

NAT14 ZNF628 SHISA7 EPN1

1.68e-04125100419q13.42
Cytoband1p36.3

MTHFR TP73

4.20e-041410021p36.3
GeneFamilyCollagens

COL4A1 COL4A2 COL4A4 COL27A1

1.84e-0546624490
GeneFamilyAtaxins|Trinucleotide repeat containing

TNRC6C KMT2D TNRC6A

8.37e-0525623775
GeneFamilyPotassium voltage-gated channels

KCNH3 KCNG2 KCNH2

3.47e-0440623274
GeneFamilyZinc fingers MYND-type

ZMYND15 USP19

2.33e-032162287
GeneFamilyPOU class homeoboxes and pseudogenes

POU5F1 POU5F1B

2.79e-0323622523
CoexpressionNABA_BASEMENT_MEMBRANES

COL4A1 COL4A2 COL4A4 HSPG2 COLQ

3.91e-0740985M5887
CoexpressionHEBERT_MATRISOME_TNBC_LUNG_METASTASIS

COL4A1 COL4A2 COL4A4 HSPG2

1.54e-0623984M48001
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_FGF3

SH3RF1 POU5F1 POU5F1B

4.19e-069983MM608
CoexpressionNABA_CORE_MATRISOME

COL4A1 COL4A2 COL4A4 HSPG2 COL27A1 EMID1 COLQ NCAN

8.08e-06270988MM17057
CoexpressionNABA_CORE_MATRISOME

COL4A1 COL4A2 COL4A4 HSPG2 COL27A1 EMID1 COLQ NCAN

9.23e-06275988M5884
CoexpressionNABA_COLLAGENS

COL4A1 COL4A2 COL4A4 COL27A1

2.03e-0543984MM17060
CoexpressionNABA_COLLAGENS

COL4A1 COL4A2 COL4A4 COL27A1

2.22e-0544984M3005
CoexpressionHEVNER_TELENCEPHALON_VASCULAR_ENDOTHELIUM_AND_MENINGEAL_CELLS

COL4A1 COL4A2 HSPG2

2.23e-0515983MM402
CoexpressionGSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP

APBB1 IRF5 POU5F1B CELSR2 NFATC3 DSTYK

1.05e-04199986M7259
CoexpressionGSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_DN

KRBA1 MTHFR KCNH2 DHX35 PIGO TEDC1

1.08e-04200986M6208
CoexpressionAtlasgudmap_RNAseq_e11.5_Ureteric_tips_2500_K1

ZMYND15 MAPK8IP1 KMT2B ZNF628 ZBTB9 ADAM11 SPRED3 PHOX2A C1orf226 CELSR2 KCNH2 ZFHX2 PPP1R3F CACNA1H EPN1 LEF1 TEDC1

3.47e-0610009917gudmap_RNAseq_e11.5_Ureteric_tips_2500_K1
CoexpressionAtlasgudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0

MAPK8IP1 HSPG2 SH3RF1 ZNF628 SYT3 ZBTB9 ADAM11 SHISA7 MSMP SPRED3 ITPKC C1orf226 CELSR2 NEK8 ZFHX2 CACNA1H EPN1 LEF1 TEDC1

5.83e-0612759919gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 COL4A4 SH3RF1 ARHGAP23 PERM1 TIE1 NOS3

9.87e-0918610082cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 COL4A4 SH3RF1 ARHGAP23 PERM1 TIE1 NOS3

9.87e-09186100890d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCellAT1_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A2 COL4A4 HSPG2 ARHGAP23 POU5F1 LRCH4

1.47e-071761007458720776b0151cd55acc352d509599cb62f0ca8
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A1 COL4A2 ARHGAP23 MSMP PDLIM4 TIE1 NOS3

1.64e-0717910079fd9b136ecbcbd4e4f0d5875ede98d8d48608afb
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Lymphatic|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

COL4A1 COL4A2 ARHGAP23 EMID1 MSMP PDLIM4 TIE1

2.46e-0719010078d6ec2fc0af19a5cb16fff34f8b131b71b33d45f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 COL4A2 HSPG2 ARHGAP23 EMID1 TIE1 NOS3

3.04e-0719610077cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCell11.5-Distal-Mesenchymal-Airway_Smooth_Muscle|Distal / Age, Tissue, Lineage and Cell class

COL4A1 COL4A2 NAT14 COL27A1 PDLIM4 FBXL22 KCNH2

3.04e-07196100705530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 COL4A2 HSPG2 ARHGAP23 EMID1 TIE1 NOS3

3.04e-0719610074cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 COL4A2 HSPG2 ARHGAP23 EMID1 TIE1 NOS3

3.04e-071961007d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCellmetastatic_Brain-Endothelial_cells|metastatic_Brain / Location, Cell class and cell subclass

COL4A1 COL4A2 HSPG2 MSMP TIE1 LEF1 NOS3

3.26e-07198100797ef7946ef11ac93318c1dd46b548dc01e5a6aba
ToppCell11.5-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

COL4A1 COL4A2 NAT14 COL27A1 FBXL22 KCNH2 LEF1

3.37e-0719910071a8c77d241bd817a195e1532fd25f51358cb1ff1
ToppCellmetastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs|metastatic_Lymph_Node / Location, Cell class and cell subclass

COL4A1 COL4A2 HSPG2 ARHGAP23 EMID1 TIE1

2.71e-061741006d551bc29afef071adf4c9bb80345352ec33441d8
ToppCellAT1_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A2 COL4A4 HSPG2 ITPKC LRCH4

2.89e-0617610064a30bb771297b30926fb98e2b5ec0dbdc46feac7
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 TIE1 NCAN NOS3 PRRT4 TP73

3.19e-061791006a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellcritical-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

HSPG2 EMID1 LRRC4B TIE1 KCNH2 CACNA1H

3.40e-061811006f0d81ae74d3f32979624a94b2ef93774831a7970
ToppCelldroplet-Liver-Npc-21m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 HSPG2 SH3RF1 ARHGAP23 TIE1 NOS3

3.51e-061821006dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 CYP1A1 HSPG2 TIE1 PRRT4

3.51e-0618210063b4dbf61ca0fe50efe05449815630e301cb76630
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 CYP1A1 HSPG2 TIE1 PRRT4

3.51e-061821006ab5761bf9af439231cd0f487b6467e372672a517
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 HSPG2 SH3RF1 ARHGAP23 TIE1 NOS3

3.51e-061821006010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 HSPG2 SH3RF1 ARHGAP23 TIE1 NOS3

3.51e-061821006b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PERM1 TIE1 NCAN NOS3 PRRT4 TP73

3.74e-061841006f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PERM1 TIE1 NCAN NOS3 PRRT4 TP73

3.74e-0618410068bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAT14 COL27A1 ADAM11 PDLIM4 KCNH2 PRNP

4.10e-0618710066f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCellEndothelial-A-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A2 HSPG2 ARHGAP23 PDLIM4 NOS3

4.10e-061871006febe0b99a6a815ce687160a0e7af55228b1d5beb
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 COL4A4 SH3RF1 PERM1 TIE1 NOS3

4.36e-061891006ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 KCNG2 FBXL22 KCNH2 CACNA1H MYO18B

4.63e-061911006c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 KCNG2 FBXL22 KCNH2 CACNA1H MYO18B

4.63e-061911006715f5b449b8e075959c05a5b38389df319663164
ToppCelldroplet-Heart-nan-18m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 KCNG2 FBXL22 KCNH2 CACNA1H MYO18B

4.77e-0619210060bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A4 HSPG2 ARHGAP23 TIE1 NOS3

4.77e-0619210062bfac6b3956265205ca47d06888851ed68b65999
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A4 HSPG2 ARHGAP23 TIE1 NOS3

4.77e-061921006d525f7f088a53110912600a7c9f6d33b9270d534
ToppCelldroplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 KCNG2 FBXL22 KCNH2 CACNA1H MYO18B

4.77e-061921006d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCellfacs-BAT-Fat-3m-Endothelial-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 CYP1A1 HSPG2 TIE1 NOS3

4.92e-061931006e340064cd146deac03f2d0fd43e2e218bb6057c9
ToppCellCOPD-Endothelial-Lymphatic|COPD / Disease state, Lineage and Cell class

COL4A1 COL4A2 HSPG2 ARHGAP23 PDLIM4 TIE1

4.92e-06193100618bcf08068a236c4575c7a07181ac893dfdcbeeb
ToppCellfacs-BAT-Fat-3m-Endothelial-endothelial_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 CYP1A1 HSPG2 TIE1 NOS3

4.92e-061931006a211b386fd0fb9da9937361d29d90925a72c9715
ToppCellfacs-BAT-Fat-3m-Endothelial|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 CYP1A1 HSPG2 TIE1 NOS3

4.92e-0619310063086c33f4d6fab66966818737f95ae4d6b2615b0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 COL4A2 HSPG2 TIE1 LEF1 NOS3

5.22e-0619510064658fb197657d7692ee344ae76b11b0210c418ba
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 COL4A2 HSPG2 ARHGAP23 ITPKC NOS3

5.22e-061951006818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 COL4A2 HSPG2 ARHGAP23 TIE1 NOS3

5.22e-06195100685df110f753f58ab017018c54ee454edb4428e29
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 LRRC4B KCNG2 FBXL22 KCNH2 MYO18B

5.37e-061961006a582130862bee76c0385156a333bfdfc75cf218b
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 LRRC4B KCNG2 FBXL22 KCNH2 MYO18B

5.37e-061961006fba52a4b82086dbae9a55038bf44c4539be926f5
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 COL4A2 HSPG2 TIE1 LEF1 NOS3

5.69e-061981006218f33e068eb126458ec33176de3cfa6fc06ddf0
ToppCell390C-Endothelial_cells-Endothelial-A_(Artery)-|390C / Donor, Lineage, Cell class and subclass (all cells)

COL4A1 COL4A2 HSPG2 ARHGAP23 TIE1 NOS3

5.69e-061981006f83956c4b13b5d0a0c6e3d9f580dbf99649ef175
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 COL4A2 HSPG2 TIE1 LEF1 NOS3

5.69e-06198100672e8b9cccb7b0a2ea9d415218fff4fa2f09728f4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 COL4A2 HSPG2 TIE1 LEF1 NOS3

5.69e-061981006e1fa02184ce93c4f8aa5cf04b70949cd4c425ff0
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

COL4A1 COL4A2 HSPG2 ARHGAP23 TIE1 NOS3

5.69e-06198100656b746e5791b47fe33a7872f0942ae0747b13d4a
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Endothelial|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

COL4A1 COL4A2 HSPG2 ARHGAP23 TIE1 NOS3

5.69e-061981006531b0f88c95f813e3914c96749f591e80ca321d0
ToppCell390C-Endothelial_cells-Endothelial-A_(Artery)|390C / Donor, Lineage, Cell class and subclass (all cells)

COL4A1 COL4A2 HSPG2 ARHGAP23 TIE1 NOS3

5.69e-0619810065b5ccce5de82ea041465e656147cec3b8beb865b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 COL4A2 HSPG2 TIE1 LEF1 NOS3

5.86e-0619910069c40b3ee39860e9d8edafd007daec11abdd95435
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 COL4A2 HSPG2 TIE1 LEF1 NOS3

5.86e-06199100672b34bce8157abe389e95cd3ed8ba578dce0cbf6
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 COL4A2 HSPG2 MSMP TIE1 NOS3

5.86e-0619910060602e2b2aa56d106da63bd342a38bef437b4d496
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A1 COL4A2 HSPG2 MSMP TIE1 NOS3

5.86e-061991006463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCellBiopsy_Other_PF-Endothelial|Biopsy_Other_PF / Sample group, Lineage and Cell type

COL4A1 COL4A2 HSPG2 ARHGAP23 TIE1 NOS3

6.03e-062001006f9916134486fb1dac55f5e7e8deb35e7a3b85770
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_immature_4|E18.5-samps / Age Group, Lineage, Cell class and subclass

NAT14 GGN SSTR4 SHISA7 DHX35

1.13e-051301005169d88bffd7cd813a484d809defa638ceaca4bcb
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Mucinous_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

MAPK8IP1 CALHM1 CCDC187 KCNH2 IGSF9B

1.61e-05140100582b150e9e9962460a5cd6bef7ee04f28f5c05d1a
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADAM11 KCNH3 KCNG2 ZFHX2 CACNA1H

2.04e-0514710058f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCellnormal_Lung-Endothelial_cells-Tumor_ECs|Endothelial_cells / Location, Cell class and cell subclass

ZMYND15 COL4A1 COL4A2 HSPG2 KCNH3

2.55e-051541005afdc385397c7b13c9348eeef95f109f2363057ae
ToppCellAT1-AT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A2 COL4A4 POU5F1 ITPKC

2.63e-051551005010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 COL4A2 COL4A4 KRT78 BRSK1

3.25e-0516210055f009b231f21861afee9cc0c569082e1135f929c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 COL4A2 COL4A4 KRT78 BRSK1

3.25e-051621005b936f8040dcd4db621ccded19237af8df7d0ed6e
ToppCellLeuk-UTI-Lymphocyte-T_NK-CD4_TEM|Leuk-UTI / Disease, Lineage and Cell Type

BEX5 APBB1 TNRC6C COLQ CACNA1H

3.55e-05165100508285c09de16ed4f488abb655a22f54bc07968ae
ToppCellcritical-Myeloid-Mast_cell|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

EMID1 LRRC4B TIE1 KCNH2 CACNA1H

3.55e-05165100534a1cc6ccd46c059354e8fbde1ac69f202695a4e
ToppCellNS-critical-d_07-13-Myeloid-Mast_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EMID1 LRRC4B TIE1 KCNH2 CACNA1H

3.76e-0516710058a14fd980d8ebe8ef0216221f619d31aaa27ff15
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADAM11 SSTR4 KCNH3 KCNG2 CACNA1H

3.87e-0516810056db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 COL4A2 HSPG2 TIE1 PRRT4

3.98e-0516910050d8b681404e18f3061d84425fb5f7d84e8e2b8d7
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 EMID1 ZNF696 CELSR2 IGSF9B

3.98e-0516910052833a8a7094e4d407eb923f2bc59b9b112c6bae4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 COL4A2 HSPG2 COL27A1 MEIOSIN

4.21e-051711005972fab891135bd755d5526cbc5a963200067b0a6
ToppCelldroplet-Lung-nan-21m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 ADAM11 SPRED3 KCNH3 KCNG2

4.21e-051711005159ce6d5513008532dd7785b915b3fe7440cc4b2
ToppCellAT1-AT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A4 POU5F1 PDLIM4 LRCH4

4.21e-0517110050b9912f07393aca889db72b40da08e0bc9bc1e8c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A1 COL4A2 HSPG2 COL27A1 MEIOSIN

4.21e-0517110052a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellEndothelial-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A2 PDLIM4 TIE1 NOS3

4.32e-0517210058a527dff06d841a86c7eb04a1dd9630787294da4
ToppCellControl-Endothelial_cells-Systemic_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

COL4A1 COL4A2 HSPG2 TIE1 NOS3

4.32e-051721005c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3RF1 EMID1 ITPKC PPP1R3F LEF1

4.45e-0517310053059325901b1e5e12a1a91183f14267288b2f600
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A1 COL4A2 TIE1 NOS3 PRRT4

4.45e-051731005ad9777e4ae70b11676ec735eb6db91776ca0cb19
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3RF1 EMID1 ITPKC PPP1R3F LEF1

4.45e-05173100536c8338463ee4cc432f568728d55989360f9a68d
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

CYP1A1 GGN RAX RBM46

4.64e-058810042075743c7c0b6d74e80464a6bc776206d744d502
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)|Cerebellum / BrainAtlas - Mouse McCarroll V32

CYP1A1 GGN RAX RBM46

4.64e-05881004a49319bc97188550e08248973e10c626124c3917
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Bergmann_Glia_(Slc1a3)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

CYP1A1 GGN RAX RBM46

4.64e-0588100414b11249a2b3fa327622897fe74630c2697ea47e
ToppCellHealthy_Control-Myeloid-Mast|Healthy_Control / Condition, Lineage, Cell class and cell subclass

HSPG2 EMID1 LRRC4B TIE1 KCNH2

4.70e-051751005ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCellAT1-AT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A2 COL4A4 APBB1 COLQ

4.70e-051751005bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCellAT1-AT2_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A2 COL4A4 ARHGAP23 LRCH4

4.70e-0517510059a95ab5c361ebaa8747983c5a0d69025682a19ad
ToppCellHealthy_Control-Myeloid-Mast-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

HSPG2 EMID1 LRRC4B TIE1 KCNH2

4.70e-051751005eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APBB1 PERM1 COLQ FBXL22 MYO18B

4.96e-051771005692cd03bf0958ebeec34d41bfe87713a768e9a8e
ToppCellmetastatic_Lymph_Node-Endothelial_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

COL4A1 COL4A2 HSPG2 ARHGAP23 TIE1

4.96e-05177100571bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APBB1 PERM1 COLQ FBXL22 MYO18B

4.96e-051771005c08583ea68bbeb6b5de852a46b0c0f04792dae55
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 COL4A2 HSPG2 TIE1 PRRT4

4.96e-051771005fdf2af00fc971f0cd3915e1416e4a256458d6ea8
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 COL4A2 SYT3 LRRC4B CACNA1H

4.96e-051771005452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 COL4A2 HSPG2 TIE1 PRRT4

4.96e-05177100512f8627124acbf436e75681ff1ce429ff5e3f256
ToppCelltumor_Lung-Endothelial_cells-EPCs|tumor_Lung / Location, Cell class and cell subclass

COL4A1 COL4A2 HSPG2 KCNH3 TIE1

4.96e-051771005f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZMYND15 ADAM11 SPRED3 KCNH3 HIVEP3

5.23e-0517910054f20540bfbcefe0e83812be7ea542e8bb3bf19bc
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A1 COL4A2 LRRC4B AGMO CACNA1H

5.23e-051791005dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCelldroplet-Lung-nan-21m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 ADAM11 SPRED3 KCNH3 HIVEP3

5.23e-051791005d78eacf47847a50888dd16c35bed9b7afc80010f
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 SPRED3 C1orf226 TIE1 NOS3

5.23e-051791005d2db9e70b780643f1e004c41a70464d0abe26088
ToppCellAT1_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A1 COL4A2 COL4A4 ARHGAP23 LRCH4

5.37e-051801005e1964002681f80d8d62406b6ee52a01e1829ccf2
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL4A1 COL4A2 SH3RF1 COL27A1 CACNA1H

5.51e-05181100533cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-proliferating_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL4A1 COL4A2 HSPG2 TIE1 NOS3

5.66e-051821005997d37ca2af661c92a56add888762724dfccc890
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PERM1 TIE1 NCAN PRRT4 TP73

5.80e-0518310056f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL4A1 COL4A2 SPRED3 CACNA1H LEF1

6.11e-051851005a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

COL4A1 COL4A2 LRRC4B CACNA1H LEF1

6.11e-0518510054905adaeeffd353e089578e5ea614437dbe794e6
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAB2 ARHGAP30 ADD1 HIVEP3 LEF1

6.11e-051851005a2cae8c657e4f4d121476798e424876f7e247973
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HTR6 COLQ RAX RBM46 BRSK1

6.11e-051851005355b03c7ea438681e11a2b872c798c9ea26e1486
Diseaseatherosclerosis (is_implicated_in)

COL4A2 ADD1 MTHFR NOS3

1.71e-0716944DOID:1936 (is_implicated_in)
Diseaseend stage renal disease (is_implicated_in)

COL4A4 CYP1A1 MTHFR NOS3

8.94e-0641944DOID:783 (is_implicated_in)
DiseaseDevelopmental Porencephaly

COL4A1 COL4A2

1.00e-052942C4082301
DiseaseCongenital porencephaly

COL4A1 COL4A2

1.00e-052942C0302892
DiseasePORENCEPHALY, FAMILIAL

COL4A1 COL4A2

1.00e-052942C1867983
DiseasePorencephaly, Type 1, Autosomal Dominant

COL4A1 COL4A2

1.00e-052942C4551998
DiseasePost-traumatic Porencephaly

COL4A1 COL4A2

1.00e-052942C3698507
DiseasePorencephaly

COL4A1 COL4A2

1.00e-052942C4082173
DiseaseHEMORRHAGE, INTRACEREBRAL, SUSCEPTIBILITY TO

COL4A1 COL4A2

1.00e-052942C3281105
DiseaseMale sterility

CYP1A1 KMT2D MTHFR NOS3

1.69e-0548944C0917731
DiseaseMale infertility

CYP1A1 KMT2D MTHFR NOS3

1.69e-0548944C0021364
DiseaseSubfertility, Male

CYP1A1 KMT2D MTHFR NOS3

1.69e-0548944C0848676
DiseaseHemorrhage, intracerebral, susceptibility to

COL4A1 COL4A2

3.01e-053942cv:C3281105
DiseaseHEMORRHAGE, INTRACEREBRAL, SUSCEPTIBILITY TO

COL4A1 COL4A2

3.01e-053942614519
Diseasemetabolic syndrome

C5orf67 HECTD4 CELSR2 KCNH2 AGMO TNRC6A

4.46e-05200946EFO_0000195
Diseaselung small cell carcinoma (is_implicated_in)

KMT2D MTHFR TP73

9.68e-0528943DOID:5409 (is_implicated_in)
Diseaselow density lipoprotein cholesterol measurement, C-reactive protein measurement

HECTD4 CELSR2 NCAN

1.90e-0435943EFO_0004458, EFO_0004611
Diseaseangle-closure glaucoma (is_implicated_in)

MTHFR NOS3

2.09e-047942DOID:13550 (is_implicated_in)
Diseasecups of coffee per day measurement

CYP1A1 HECTD4 ADD1

2.84e-0440943EFO_0006782
Diseasemyocardial infarction (is_implicated_in)

COL4A1 ADD1 MTHFR NOS3

2.88e-0499944DOID:5844 (is_implicated_in)
Diseasemigraine (is_implicated_in)

MTHFR NOS3

3.56e-049942DOID:6364 (is_implicated_in)
DiseaseEssential hypertension

ADD1 NOS3

4.44e-0410942cv:C0085580
DiseaseEssential hypertension, genetic

ADD1 NOS3

4.44e-0410942cv:CN305331
DiseaseHYPERTENSION, ESSENTIAL

ADD1 NOS3

4.44e-0410942145500
Diseaseserum alanine aminotransferase measurement

COL4A2 C5orf67 KRT78 COL27A1 SAMD4B HECTD4 CELSR2 DSTYK NCAN PRNP

4.52e-048699410EFO_0004735
Diseasecryptic phenotype measurement

COL4A2 KCNH2 NOS3

4.59e-0447943EFO_0021487
DiseaseLeukoencephalopathy

COL4A1 MTHFR

5.42e-0411942C0270612
DiseaseLong QT Syndrome

CYP1A1 KCNH2

5.42e-0411942C0023976
Diseasevon Willebrand factor measurement, coronary artery disease

COL4A1 HECTD4 CELSR2 NOS3

5.62e-04118944EFO_0001645, EFO_0004629
Diseasecollagen disease (implicated_via_orthology)

COL4A1 COL4A4

6.49e-0412942DOID:854 (implicated_via_orthology)
DiseaseEssential Hypertension

ADD1 NOS3

6.49e-0412942C0085580
DiseaseSmall cell carcinoma of lung

COL4A2 MYO18B TP73

6.90e-0454943C0149925
DiseaseAntithrombotic agent use measurement

COL4A2 HECTD4 CELSR2

7.28e-0455943EFO_0009925
Diseaseacute lymphoblastic leukemia (is_implicated_in)

CYP1A1 MTHFR NOS3

7.28e-0455943DOID:9952 (is_implicated_in)
DiseaseChildhood Ataxia with Central Nervous System Hypomyelinization

COL4A1 MTHFR

8.91e-0414942C1858991
Diseasenephroblastoma (is_implicated_in)

MTHFR TP73

8.91e-0414942DOID:2154 (is_implicated_in)
DiseaseLymphoma, Follicular, Grade 2

KMT2D MTHFR

1.03e-0315942C1956132
DiseaseLymphoma, Follicular, Grade 3

KMT2D MTHFR

1.03e-0315942C1956131
DiseaseLymphoma, Follicular, Grade 1

KMT2D MTHFR

1.03e-0315942C1956130
DiseaseLymphoma, Large-Cell, Follicular

KMT2D MTHFR

1.03e-0315942C0079745
DiseaseLymphoma, Small Cleaved-Cell, Follicular

KMT2D MTHFR

1.03e-0315942C0079765
DiseaseLymphoma, Mixed-Cell, Follicular

KMT2D MTHFR

1.03e-0315942C0079758
Diseaseparental longevity

COL4A1 HECTD4 PERM1 POU5F1 COLQ PHOX2A CELSR2

1.03e-03494947EFO_0007796
DiseaseBladder Neoplasm

CALHM1 KMT2D MTHFR NCAN

1.06e-03140944C0005695
Diseasenon-lobar intracerebral hemorrhage

COL4A1 COL4A2 MYO18B

1.08e-0363943EFO_0010178
DiseaseMalignant neoplasm of urinary bladder

CALHM1 KMT2D MTHFR NCAN

1.09e-03141944C0005684
Diseasearterial stiffness measurement

COL4A1 COL4A2 DRAXIN

1.13e-0364943EFO_0004517
DiseaseDiabetic Angiopathies

MTHFR NOS3

1.17e-0316942C0011875
DiseaseMicroangiopathy, Diabetic

MTHFR NOS3

1.17e-0316942C0025945
Diseasesickle cell anemia (is_implicated_in)

MTHFR NOS3

1.17e-0316942DOID:10923 (is_implicated_in)
DiseaseSclerocystic Ovaries

ARHGAP23 PTCRA ARHGAP30 PDLIM4

1.18e-03144944C1136382
DiseasePolycystic Ovary Syndrome

ARHGAP23 PTCRA ARHGAP30 PDLIM4

1.18e-03144944C0032460
DiseaseDementia

COL4A1 PRNP

1.32e-0317942C0497327
DiseaseKuhnt-Junius degeneration (is_implicated_in)

MTHFR NOS3

1.32e-0317942DOID:10873 (is_implicated_in)
Diseaserenal cell carcinoma (is_implicated_in)

CYP1A1 MTHFR TP73

1.41e-0369943DOID:4450 (is_implicated_in)
Diseasecoronary artery disease

COL4A1 COL4A2 COL4A4 CYP1A1 C5orf67 PTCRA HECTD4 CELSR2 MTHFR DSTYK NOS3

1.46e-0311949411EFO_0001645
Diseaseessential hypertension (is_implicated_in)

ADD1 NOS3

1.49e-0318942DOID:10825 (is_implicated_in)
DiseaseBMI-adjusted fasting blood insulin measurement

C5orf67 POU5F1B

1.49e-0318942EFO_0008037
Diseasefibrinogen measurement, coronary artery disease

COL4A1 HECTD4 CELSR2 NOS3

1.51e-03154944EFO_0001645, EFO_0004623
DiseaseParoxysmal atrial fibrillation

HSPG2 KCNH2 MYO18B NOS3

1.58e-03156944C0235480
Diseaseprostate cancer (is_marker_for)

KMT2B KMT2D LEF1 TP73

1.58e-03156944DOID:10283 (is_marker_for)
Diseasefamilial atrial fibrillation

HSPG2 KCNH2 MYO18B NOS3

1.58e-03156944C3468561
DiseasePersistent atrial fibrillation

HSPG2 KCNH2 MYO18B NOS3

1.58e-03156944C2585653
DiseaseAntihypertensive use measurement

HSPG2 TNRC6A CACNA1H LEF1 NOS3

1.61e-03265945EFO_0009927
Diseaseankylosing spondylitis (is_implicated_in)

CYP1A1 MTHFR

1.66e-0319942DOID:7147 (is_implicated_in)
Diseasehydrocephalus (implicated_via_orthology)

ADD1 CELSR2

1.66e-0319942DOID:10908 (implicated_via_orthology)
DiseaseAtrial Fibrillation

HSPG2 KCNH2 MYO18B NOS3

1.74e-03160944C0004238
Diseasewaist-hip ratio

COL4A1 COL4A2 NAT14 C5orf67 HECTD4 POU5F1B UTP18 MEGF8 DSTYK TNRC6A TP73

1.79e-0312269411EFO_0004343
DiseaseLymphoma, Follicular

KMT2D MTHFR

1.84e-0320942C0024301
Diseasesphingomyelin measurement

ZMYND15 TNRC6C KCNH3 CELSR2 NCAN

1.99e-03278945EFO_0010118
Diseasecognitive function measurement

COL4A2 ZBTB9 SSTR4 KCNH3 KCNG2 PHOX2A KMT2D TNRC6A RBM46 CACNA1H IGSF9B MYO18B

1.99e-0314349412EFO_0008354
Diseasenon-high density lipoprotein cholesterol measurement

COL4A2 C5orf67 GIGYF1 ADD1 RBCK1 CELSR2 DSTYK NCAN

2.01e-03713948EFO_0005689
Diseasechronic myeloid leukemia (is_implicated_in)

CYP1A1 MTHFR

2.03e-0321942DOID:8552 (is_implicated_in)
Diseasepulmonary hypertension (biomarker_via_orthology)

COL4A1 CYP1A1 NOS3

2.15e-0380943DOID:6432 (biomarker_via_orthology)
Diseaserheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement

KMT2B IRF5 HIVEP3 LEF1

2.17e-03170944EFO_0000685, EFO_0007791, EFO_0007837
DiseaseCardiomegaly

CYP1A1 RBCK1 NOS3

2.31e-0382943C0018800
DiseaseCardiac Hypertrophy

CYP1A1 RBCK1 NOS3

2.31e-0382943C1383860
DiseaseMorbilliform Drug Reaction

CYP1A1 MTHFR

2.43e-0323942C0406537
DiseaseDrug Eruptions

CYP1A1 MTHFR

2.43e-0323942C0011609
Diseaseacute myeloid leukemia (is_implicated_in)

CYP1A1 MTHFR NOS3

2.48e-0384943DOID:9119 (is_implicated_in)
Diseaselung squamous cell carcinoma (is_implicated_in)

KMT2D TP73

2.65e-0324942DOID:3907 (is_implicated_in)
Diseasehypertension

C5orf67 HECTD4 IRF5 MTHFR NOS3

3.05e-03307945EFO_0000537

Protein segments in the cluster

PeptideGeneStartEntry
GAGPPSAPGGSGWVA

HTR6

16

P50406
PGALGPNWGRGAPGE

CCDC187

886

A0A096LP49
SVIFKGPGWGPGKPR

AGMO

296

Q6ZNB7
GPGWGPGKPRLGLSE

AGMO

301

Q6ZNB7
LRWGGLPQLGGPGAP

ADAM11

31

O75078
DPGLPGLPGSWGAGG

COL4A4

191

P53420
DLGLPGWLGTKGDPG

COL4A4

516

P53420
GWLGTKGDPGPPGAE

COL4A4

521

P53420
LPGGKGDDGWPGAPG

COL4A2

1171

P08572
GDDGWPGAPGLPGFP

COL4A2

1176

P08572
PGAPGTPGTKGWAGD

COL4A2

1316

P08572
PLMGNGWAGGGPRPP

CALHM1

321

Q8IU99
EGGGPEPGPANAKWL

APBB1

56

O00213
STPKDGGPGPGKAPW

CELSR2

2776

Q9HCU4
GGPGPGKAPWPGDFG

CELSR2

2781

Q9HCU4
GDKGNPGWPGAPGVP

COL4A1

1266

P02462
GQRKFGGPPPGWEGP

RBM46

41

Q8TBY0
GSPTPTLEWTGGPGG

HSPG2

1891

P98160
GLKNPPGPWGWPLIG

CYP1A1

36

P04798
AGAPAGRPEGGGPWA

ITPKC

46

Q96DU7
TGEPPPGSGGLALPW

KCNH3

1041

Q9ULD8
PGGVGQITPPLGWQG

LEF1

201

Q9UJU2
GGKALPPLWPPSGLG

LRCH4

646

O75427
GIGPGVGPGSEVWGI

POU5F1B

46

Q06416
IGWPGPEGPRGEKGD

COLQ

146

Q9Y215
KPSSDPIVGWGPSGG

MTHFR

491

P42898
GDTPPGRKPGSPVWG

PTCRA

221

Q6ISU1
PWPTRKEGPGALGGE

KRBA1

161

A5PL33
PLPTLGPLWGTNGDG

GIGYF1

371

O75420
SPLPGGPGAGDPRIW

NAB2

171

Q15742
EPPGGGWRGSLGEPP

MAPK8IP1

346

Q9UQF2
TKGPRWGPGGPGDTS

RBCK1

476

Q9BYM8
GRPGGPWGESPSSGP

KCNH2

921

Q12809
PGGNVKGVWAPPAPG

BEX5

31

Q5H9J7
GSLPPPGGLGGPWVA

NAT14

86

Q8WUY8
MEPWPCSPGGGGGTR

KCNG2

1

Q9UJ96
PGGPGGPGAEDVAVW

MEGF8

731

Q7Z7M0
WEAPPLGAGGGSLLP

NEK8

356

Q86SG6
FGEWSGGPGLSLCPP

KRT78

66

Q8N1N4
WKCKEGPGPGPGTPR

KMT2B

266

Q9UMN6
QAPPGAGLGVGQGPW

IRF5

476

Q13568
GLGVWFPGSATPPGL

GGN

46

Q86UU5
GPCWVGPGPDGGLAV

NHLRC4

6

P0CG21
GIGWERTEGTPPPPG

HECTD4

2071

Q9Y4D8
GGLAGLGQKPAWGPA

MEIOSIN

136

C9JSJ3
VPWGSEPVSGPGPGG

DSTYK

6

Q6XUX3
GIGPGVGPGSEVWGI

POU5F1

46

Q01860
QLEKGSPGGPPPGWV

NOS3

831

P29474
GPGPSGLLPESWKPG

PRR35

151

P0CG20
IPNRGGPGGGPDEWA

TP73

596

O15350
SPGGWKAITEKPPGG

RBBP8NL

151

Q8NC74
GPGKKEWGPGLPSQA

DRAXIN

61

Q8NBI3
PGAWTKLPGDGGSVP

C5orf67

61

F2Z3F1
APLGSGEPGGPGLWV

C1orf226

31

A1L170
GPVKFWRPGTEGPGV

DHX35

6

Q9H5Z1
HPGPRGWPGPKGSKG

COL27A1

1386

Q8IZC6
GWPGPKGSKGAEGPK

COL27A1

1391

Q8IZC6
PPPSPGGGVGGAAWR

BRSK1

536

Q8TDC3
VDPWGGTPAPAAGEG

EPN1

331

Q9Y6I3
PWEEGKGLASPPGGG

FOXD4L1

306

Q9NU39
VGAWGLPGPTGPKGD

EMID1

196

Q96A84
GSTSPGPKGKWAGGP

CACNA1H

626

O95180
GPKGKWAGGPPGTGG

CACNA1H

631

O95180
PAGHWEAGPKGPGGV

SCAP

686

Q12770
GGPGAWEAVAVGPRP

PERM1

536

Q5SV97
GAPGAAGSWGRPVGP

D2HGDH

16

Q8N465
KEPPGPTTDGVWGGG

LRRC4B

511

Q9NT99
GPKPPIWKGSGSLEG

ARHGAP30

621

Q7Z6I6
VPWRDKGGSAVGGGP

SYT3

81

Q9BQG1
RPDWKAGAGPGGPPQ

UTP18

26

Q9Y5J1
GPPAGPGILAWGRGS

TNRC6C

301

Q9HCJ0
GSLPWPGGSAAKPGK

TADA1

81

Q96BN2
PGAGSAGGKSSPEPW

NCAN

551

O14594
GEGGDWPGPGGPRNL

PDLIM4

221

P50479
GTPIAVGPKSPRWGG

FBXL22

136

Q6P050
TLPPGGEEGLGTAWP

SSTR4

6

P31391
WATTPPPLAGGAGGA

SHISA7

136

A6NL88
LESWLGPPLPGGGAT

RAX

241

Q9Y2V3
IKQRPWKPGPGGGSG

SH3RF1

76

Q7Z6J0
PGSPVGEGTGSPPKW

ADD1

356

P35611
QGTGSWGPEPPGPGI

SENP3

6

Q9H4L4
GSGPLGPWGPQDWVG

USP19

1261

O94966
PVASGGGKAQPGSPW

ZC3H3

581

Q8IXZ2
PGGSELLLPKGFPWG

ZFHX2

131

Q9C0A1
RLPCKGGGPDPEWGS

MSMP

111

Q1L6U9
GGPAELGPGEAGPGW

SAMD4B

176

Q5PRF9
LGPGEAGPGWQDKPP

SAMD4B

181

Q5PRF9
KGWAGKSPGRGPVPA

IGSF9B

1101

Q9UPX0
WRPFKGGPGGLKGPV

SPATA8

46

Q6RVD6
GGPGGLKGPVWPAKE

SPATA8

51

Q6RVD6
LSRPGEGGEGAWGPP

TIE1

521

P35590
EWKELGGGGPPEPAG

ARHGAP23

1421

Q9P227
PEPSEPLAGAGGLGW

SPRED3

201

Q2MJR0
GPGPQPLKGALWAGV

PHOX2A

221

O14813
GLLPGDWAAPLDPGG

TEDC1

271

Q86SX3
PGKWALAGPGSPSAG

HIVEP3

2086

Q5T1R4
VPPNAGPGAEGGGSW

ZNF696

106

Q9H7X3
QGLGEGGDAWVPPTP

ZBTB4

176

Q9P1Z0
SPGGSPGGCPGEETW

NFATC3

211

Q12968
PKPGGWNTGGSRYPG

PRNP

26

P04156
GGWVTGPPDKEPLGS

PRRT4

651

C9JH25
LLPPPGAVPGGAGVW

PPP1R3F

141

Q6ZSY5
VESPAAPGKGGWPGS

MYO18B

426

Q8IUG5
GPGPTSGGGGPSWKP

ZBTB9

331

Q96C00
AQTPEGWGPDPGGLG

ZNF316

291

A6NFI3
GPGSLPWGSQGKPGA

PIGO

46

Q8TEQ8
EPGPGPGLGTAWLLG

ZMYND15

76

Q9H091
WGIPPATGKPPGTGW

TNRC6A

956

Q8NDV7
ATGKPPGTGWLGGPI

TNRC6A

961

Q8NDV7
PGTGWLGGPIPAPAK

TNRC6A

966

Q8NDV7
KAGQGAGVVWLPGPG

ZNF628

766

Q5EBL2
AGAVGPPGSWGAEPS

KMT2D

2711

O14686