Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	walking behavior	CACNA1A DAB1 SPG11 CHD7 ATP1A3	8.33e-06	60	95	5	GO:0090659
GeneOntologyBiologicalProcess	muscle structure development	DOCK2 GLMN LMOD3 TCF7L2 RARA RARB SYNE1 MFN2 SPG11 CHD7 REST CHKB FER1L5 RYR2 SMAD1	8.44e-06	858	95	15	GO:0061061
GeneOntologyBiologicalProcess	locomotory behavior	CACNA1A SOBP DAB1 SPG11 CHD7 ATP1A3 PUM1 NPAS2	5.05e-05	284	95	8	GO:0007626
GeneOntologyBiologicalProcess	organic cation transport	CACNA1A SLC43A2 KCNB1 SFXN3 ATP13A3 SLC3A2	5.66e-05	145	95	6	GO:0015695
GeneOntologyBiologicalProcess	regulation of sulfur metabolic process	CACNA1A TCF7L2 NFE2L2	6.14e-05	17	95	3	GO:0042762
GeneOntologyBiologicalProcess	methionine transport	SLC43A2 SLC3A2	6.28e-05	3	95	2	GO:0015821
GeneOntologyBiologicalProcess	import into cell	DOCK2 CACNA1A SLC43A2 MAGI2 TREX1 RARA AP2B1 SNAP91 SYNE1 AP3B2 SPG11 ATP1A3 FER1L5 LRP1B SLC3A2	1.12e-04	1074	95	15	GO:0098657
GeneOntologyBiologicalProcess	proteasomal ubiquitin-independent protein catabolic process	PSME4 NFE2L2	1.25e-04	4	95	2	GO:0010499
GeneOntologyBiologicalProcess	phenylalanine transport	SLC43A2 SLC3A2	1.25e-04	4	95	2	GO:0015823
GeneOntologyBiologicalProcess	muscle cell differentiation	DOCK2 GLMN LMOD3 RARA RARB SYNE1 MFN2 SPG11 FER1L5 SMAD1	1.67e-04	531	95	10	GO:0042692
GeneOntologyBiologicalProcess	adult locomotory behavior	CACNA1A DAB1 CHD7 ATP1A3 PUM1	2.00e-04	116	95	5	GO:0008344
GeneOntologyBiologicalProcess	L-leucine import across plasma membrane	SLC43A2 SLC3A2	2.08e-04	5	95	2	GO:1903801
GeneOntologyBiologicalProcess	isoleucine transport	SLC43A2 SLC3A2	2.08e-04	5	95	2	GO:0015818
GeneOntologyBiologicalProcess	muscle tissue development	LMOD3 TREX1 TCF7L2 RARA RARB SYNE1 SPG11 CHD7 RYR2 SMAD1	2.49e-04	558	95	10	GO:0060537
GeneOntologyBiologicalProcess	regulation of myelination	TCF7L2 RARA RARB WASF3	2.59e-04	67	95	4	GO:0031641
GeneOntologyBiologicalProcess	embryo development	GLMN FRAS1 TCF7L2 RARA RARB SOBP NFE2L2 BRD4 MYO3B ARNT2 MFN2 CHD7 REST ZMIZ1 LRP1B RYR2 SMAD1	2.77e-04	1437	95	17	GO:0009790
GeneOntologyCellularComponent	photoreceptor cell cilium	MAGI2 MYO3B KIAA1549 PCARE GRK1	4.13e-04	139	94	5	GO:0097733
GeneOntologyCellularComponent	extrinsic component of presynaptic endocytic zone membrane	AP2B1 SNAP91	4.14e-04	7	94	2	GO:0098894
GeneOntologyCellularComponent	photoreceptor inner segment	MAGI2 MYO3B PCARE ATP1A3	4.24e-04	78	94	4	GO:0001917
GeneOntologyCellularComponent	extrinsic component of synaptic membrane	MAGI2 AP2B1 SNAP91	5.19e-04	35	94	3	GO:0099243
GeneOntologyCellularComponent	9+0 non-motile cilium	MAGI2 MYO3B KIAA1549 PCARE GRK1	6.40e-04	153	94	5	GO:0097731
MousePheno	narrow eye opening	FRAS1 RARA RARB CHD7 CLEC16A	9.37e-06	50	80	5	MP:0005287
MousePheno	abnormal eyelid aperture	FRAS1 RARA RARB CHD7 CLEC16A	2.13e-05	59	80	5	MP:0003671
MousePheno	abnormal brain wave pattern	CACNA1A SNAP91 PER1 RYR2 NPAS2	3.17e-05	64	80	5	MP:0004994
MousePheno	hemiplegia	CACNA1A ATP1A3	3.23e-05	2	80	2	MP:0031202
Domain	ARM-like	DOCK2 PSME4 AP2B1 AP3B2 MROH7 BTAF1 HUWE1 PUM1 PPP6R2	5.59e-06	270	89	9	IPR011989
Domain	Coatomer/clathrin_app_Ig-like	GGA2 AP2B1 AP3B2	2.23e-05	12	89	3	IPR013041
Domain	ARM-type_fold	DOCK2 PSME4 AP2B1 AP3B2 MROH7 BTAF1 HUWE1 PUM1 PPP6R2	3.41e-05	339	89	9	IPR016024
Domain	FAM47	FAM47A FAM47C	1.34e-04	4	89	2	PF14642
Domain	Retinoic_acid_rcpt	RARA RARB	1.34e-04	4	89	2	IPR003078
Domain	FAM47	FAM47A FAM47C	1.34e-04	4	89	2	IPR032743
Domain	PAS_fold_3	ARNT2 PER1 NPAS2	1.73e-04	23	89	3	IPR013655
Domain	PAS_3	ARNT2 PER1 NPAS2	1.73e-04	23	89	3	PF08447
Domain	PAS-assoc_C	ARNT2 PER1 NPAS2	1.97e-04	24	89	3	IPR000700
Domain	AP_beta	AP2B1 AP3B2	2.22e-04	5	89	2	IPR026739
Domain	PAC	ARNT2 PER1 NPAS2	2.51e-04	26	89	3	IPR001610
Domain	PAC	ARNT2 PER1 NPAS2	2.51e-04	26	89	3	SM00086
Domain	PAC	ARNT2 PER1 NPAS2	2.51e-04	26	89	3	PS50113
Domain	Clathrin_g-adaptin_app	GGA2 AP3B2	3.33e-04	6	89	2	IPR008153
Domain	-	GGA2 AP3B2	3.33e-04	6	89	2	2.60.40.1230
Domain	PAS	ARNT2 PER1 NPAS2	4.69e-04	32	89	3	SM00091
Domain	PAS	ARNT2 PER1 NPAS2	5.62e-04	34	89	3	IPR000014
Domain	PAS	ARNT2 PER1 NPAS2	5.62e-04	34	89	3	PS50112
Domain	Nuc_translocat	ARNT2 NPAS2	6.17e-04	8	89	2	IPR001067
Domain	-	PSME4 AP2B1 AP3B2 MROH7 BTAF1 PUM1	6.74e-04	222	89	6	1.25.10.10
Domain	Clathrin_a/b/g-adaptin_app_Ig	GGA2 AP2B1	7.91e-04	9	89	2	IPR008152
Domain	Alpha_adaptinC2	GGA2 AP2B1	7.91e-04	9	89	2	PF02883
Domain	Alpha_adaptinC2	GGA2 AP2B1	7.91e-04	9	89	2	SM00809
Domain	Clathrin/coatomer_adapt-like_N	AP2B1 AP3B2	2.26e-03	15	89	2	IPR002553
Domain	Adaptin_N	AP2B1 AP3B2	2.26e-03	15	89	2	PF01602
Domain	P-loop_NTPase	MAGI2 DDX19A IQCA1 TOR2A ABCB5 MYO3B MFN2 GBP2 BTAF1 CHD7 DNAH6	2.28e-03	848	89	11	IPR027417
Domain	WH2	LMOD3 WASF3	2.58e-03	16	89	2	PF02205
Domain	ATPase_P-typ_cation-transptr_C	ATP13A3 ATP1A3	2.91e-03	17	89	2	IPR006068
Domain	Cation_ATPase_C	ATP13A3 ATP1A3	2.91e-03	17	89	2	PF00689
Domain	Cation_ATPase_N	ATP13A3 ATP1A3	3.27e-03	18	89	2	PF00690
Domain	ATPase_P-typ_cation-transptr_N	ATP13A3 ATP1A3	3.64e-03	19	89	2	IPR004014
Domain	WH2_dom	LMOD3 WASF3	4.45e-03	21	89	2	IPR003124
Domain	HEAT_REPEAT	PSME4 MROH7 BTAF1	4.55e-03	70	89	3	PS50077
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	NFE2L2 PER1 USP54 REST HUWE1 PUM1 PRRC2A SON	2.56e-07	232	95	8	25515538
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CACNA1A MAGI2 CDKL5 FARSA AP2B1 SNAP91 SYNE1 AP3B2 SFXN3 KIAA1549 USP54 ATP1A3 PPP6R2 DNAH6 PRRC2A PRPF40A SLC3A2	3.10e-07	1431	95	17	37142655
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	SECISBP2L GLMN DDX19A EARS2 TOR2A NCAPH2 USP54 HUWE1 PUM1 CLEC16A SON	8.54e-07	606	95	11	36538041
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1A MAGI2 FARSA KCNB1 AP2B1 SNAP91 SYNE1 SFXN3 MFN2 CHD7 HUWE1 PPP6R2 PRRC2A	2.23e-06	963	95	13	28671696
Pubmed	BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.	DOCK2 DDX19A EARS2 BRD4 PER1 CHD7 NCAPH2 USP54 NUP35	2.31e-06	419	95	9	33001583
Pubmed	Recurrent RARB Translocations in Acute Promyelocytic Leukemia Lacking RARA Translocation.	RARA RARB	7.38e-06	2	95	2	29921692
Pubmed	Retinoic acid receptors in normal growth and development.	RARA RARB	7.38e-06	2	95	2	1330302
Pubmed	Biological functional annotation of retinoic acid alpha and beta in mouse liver based on genome-wide binding.	RARA RARB	7.38e-06	2	95	2	24833708
Pubmed	Reexpression of retinoic acid receptor (RAR) gamma or overexpression of RAR alpha or RAR beta in RAR gamma-null F9 cells reveals a partial functional redundancy between the three RAR types.	RARA RARB	7.38e-06	2	95	2	7644503
Pubmed	Cardiac ryanodine receptors control heart rate and rhythmicity in adult mice.	A1CF RYR2	7.38e-06	2	95	2	22869620
Pubmed	Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.	RARA NFE2L2	7.38e-06	2	95	2	18048326
Pubmed	Compartment-selective sensitivity of cardiovascular morphogenesis to combinations of retinoic acid receptor gene mutations.	RARA RARB	7.38e-06	2	95	2	9168777
Pubmed	Retinoic acid regulates gene expression of retinoic acid receptors alpha, beta and gamma in F9 mouse teratocarcinoma cells.	RARA RARB	7.38e-06	2	95	2	1334013
Pubmed	Cardiomyocyte ATP production, metabolic flexibility, and survival require calcium flux through cardiac ryanodine receptors in vivo.	A1CF RYR2	7.38e-06	2	95	2	23678000
Pubmed	Purification and crystallization of the heterodimeric complex of RARbeta and RXRalpha ligand-binding domains in the active conformation.	RARA RARB	7.38e-06	2	95	2	15159591
Pubmed	Generation and characterization of a mouse model harboring the exon-3 deletion in the cardiac ryanodine receptor.	A1CF RYR2	7.38e-06	2	95	2	24743769
Pubmed	[The significance of expression of isoforms RARa1 and RARa2 in response to medicinal therapy and in evaluation of total survival of patients with primarily detected multiple myeloma].	RARA RARB	7.38e-06	2	95	2	30601638
Pubmed	PCARE and WASF3 regulate ciliary F-actin assembly that is required for the initiation of photoreceptor outer segment disk formation.	WASF3 PCARE	7.38e-06	2	95	2	32312818
Pubmed	Association between nuclear expression of retinoic acid receptor alpha and beta and clinicopathological features and prognosis of advanced non-small cell lung cancer.	RARA RARB	7.38e-06	2	95	2	27306217
Pubmed	Anticancer effect of retinoic acid via AP-1 activity repression is mediated by retinoic acid receptor alpha and beta in gastric cancer cells.	RARA RARB	7.38e-06	2	95	2	12009305
Pubmed	Cardiac Ryanodine Receptor (Ryr2)-mediated Calcium Signals Specifically Promote Glucose Oxidation via Pyruvate Dehydrogenase.	A1CF RYR2	7.38e-06	2	95	2	27621312
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MAGI2 FRAS1 KANK1 SYNE1 MFN2 PUM1 CLEC16A SON	1.64e-05	407	95	8	12693553
Pubmed	Defining the membrane proteome of NK cells.	DOCK2 DDX19A FARSA AP2B1 APMAP MED14 CD74 ATP13A3 NCAPH2 HUWE1 PRRC2A PRPF40A SLC3A2	1.76e-05	1168	95	13	19946888
Pubmed	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	SYNE1 ARNT2 ZMIZ1	1.85e-05	19	95	3	18711365
Pubmed	Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants.	RARA RARB	2.21e-05	3	95	2	7607068
Pubmed	Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants.	RARA RARB	2.21e-05	3	95	2	7607067
Pubmed	Impaired distribution of retinoic acid receptors in the hindgut-tailgut region of murine embryos with anorectal malformations.	RARA RARB	2.21e-05	3	95	2	11172439
Pubmed	Cloning of several genes coding for retinoic acid nuclear receptors in the mouse embryonal carcinoma cell line PCC7-MZ1.	RARA RARB	2.21e-05	3	95	2	8383767
Pubmed	Retinoic acid receptor gamma: specific immunodetection and phosphorylation.	RARA RARB	2.21e-05	3	95	2	1655807
Pubmed	Autophagy Controls Nrf2-Mediated Dichotomy in Pressure Overloaded Hearts.	A1CF NFE2L2	2.21e-05	3	95	2	34054582
Pubmed	Contribution of retinoic acid receptor beta isoforms to the formation of the conotruncal septum of the embryonic heart.	RARA RARB	2.21e-05	3	95	2	9659935
Pubmed	Smad1, beta-catenin and Tcf4 associate in a molecular complex with the Myc promoter in dysplastic renal tissue and cooperate to control Myc transcription.	TCF7L2 SMAD1	2.21e-05	3	95	2	15576399
Pubmed	Role of cardiac mitofusins in cardiac conduction following simulated ischemia-reperfusion.	A1CF MFN2	2.21e-05	3	95	2	36473917
Pubmed	Inhibition of histone deacetylase activity by trichostatin A modulates gene expression during mouse embryogenesis without apparent toxicity.	RARA RARB	2.21e-05	3	95	2	11245412
Pubmed	mRNA expression pattern of retinoic acid and retinoid X nuclear receptor subtypes in human thyroid papillary carcinoma.	RARA RARB	2.21e-05	3	95	2	23969901
Pubmed	BRD4-binding enhancer promotes CRC progression by interacting with YY1 to activate the Wnt pathway through upregulation of TCF7L2.	TCF7L2 BRD4	2.21e-05	3	95	2	37879498
Pubmed	Altered expression of retinoic acid (RA) receptor mRNAs in the fetal mouse secondary palate by all-trans and 13-cis RAs: implications for RA-induced teratogenesis.	RARA RARB	2.21e-05	3	95	2	10100049
Pubmed	Retinoic acid receptor-beta: immunodetection and phosphorylation on tyrosine residues.	RARA RARB	2.21e-05	3	95	2	1283441
Pubmed	Synergistic activation of RARβ and RARγ nuclear receptors restores cell specialization during stem cell differentiation by hijacking RARα-controlled programs.	RARA RARB	2.21e-05	3	95	2	36446525
Pubmed	TRIM16 controls assembly and degradation of protein aggregates by modulating the p62-NRF2 axis and autophagy.	TRIM16 NFE2L2	2.21e-05	3	95	2	30143514
Pubmed	BRD4 interacts with PML/RARα in acute promyelocytic leukemia.	RARA BRD4	2.21e-05	3	95	2	30552662
Pubmed	Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies.	RARA RARB	2.21e-05	3	95	2	15528208
Pubmed	Chromosomal assignment of retinoic acid receptor (RAR) genes in the human, mouse, and rat genomes.	RARA RARB	2.21e-05	3	95	2	1655630
Pubmed	Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.	MFN2 HUWE1	2.21e-05	3	95	2	22748923
Pubmed	Association of Per1 and Npas2 with autistic disorder: support for the clock genes/social timing hypothesis.	PER1 NPAS2	2.21e-05	3	95	2	17264841
Pubmed	Immunolocalization of retinoic acid receptors in rat, mouse and human ovary and uterus.	RARA RARB	2.21e-05	3	95	2	8136307
Pubmed	Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice.	A1CF MFN2	2.21e-05	3	95	2	26785495
Pubmed	Retinoic acid and mouse skin morphogenesis. I. Expression pattern of retinoic acid receptor genes during hair vibrissa follicle, plantar, and nasal gland development.	RARA RARB	2.21e-05	3	95	2	8027572
Pubmed	Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominantly expressed in skin.	RARA RARB	2.21e-05	3	95	2	2544807
Pubmed	[Genetic expression and morphogenesis of the skin in vertebrates].	RARA RARB	2.21e-05	3	95	2	8099268
Pubmed	Characterization of retinoic acid receptor-deficient keratinocytes.	RARA RARB	2.21e-05	3	95	2	10748128
Pubmed	The short isoform of PML-RARα activates the NRF2/HO-1 pathway through a direct interaction with NRF2.	RARA NFE2L2	2.21e-05	3	95	2	28777872
Pubmed	Strain difference and mode of inheritance of the susceptibility to passive cutaneous anaphylaxis mediated by allogeneic IgE antibody in the mouse.	RARA RARB	2.21e-05	3	95	2	2737701
Pubmed	Combinatorial knockout of RARα, RARβ, and RARγ completely abrogates transcriptional responses to retinoic acid in murine embryonic stem cells.	RARA RARB	2.21e-05	3	95	2	29848550
Pubmed	A redundant oncogenic potential of the retinoic receptor (RAR) alpha, beta and gamma isoforms in acute promyelocytic leukemia.	RARA RARB	2.21e-05	3	95	2	17252005
Pubmed	Retinoic acid down-regulation of fibronectin and retinoic acid receptor alpha proteins in NIH-3T3 cells. Blocks of this response by ras transformation.	RARA RARB	2.21e-05	3	95	2	8626453
Pubmed	Function of retinoic acid receptor gamma in the mouse.	RARA RARB	2.21e-05	3	95	2	8388780
Pubmed	Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction.	A1CF MFN2	2.21e-05	3	95	2	27228353
Pubmed	Retinoids and vertebrate development.	RARA RARB	2.21e-05	3	95	2	7910825
Pubmed	Tissue-specific expression of retinoic acid receptor isoform transcripts in the mouse embryo.	RARA RARB	2.21e-05	3	95	2	10842077
Pubmed	Nrf2-Mediated Cardiac Maladaptive Remodeling and Dysfunction in a Setting of Autophagy Insufficiency.	A1CF NFE2L2	2.21e-05	3	95	2	26573705
Pubmed	Both retinoic acid receptors alpha (RARalpha) and gamma (RARgamma) are able to initiate mouse upper-lip skin glandular metaplasia.	RARA RARB	2.21e-05	3	95	2	9699718
Pubmed	Mammalian hexokinase 1: evolutionary conservation and structure to function analysis.	RARA RARB	2.21e-05	3	95	2	1783373
Pubmed	Association of retinoic acid receptor genes with meningomyelocele.	RARA RARB	2.21e-05	3	95	2	21254357
Pubmed	Circadian genes and risk of prostate cancer: Findings from the EPICAP study.	PER1 NPAS2	2.21e-05	3	95	2	30665264
Pubmed	Arg278, but not Lys229 or Lys236, plays an important role in the binding of retinoic acid by retinoic acid receptor gamma.	RARA RARB	2.21e-05	3	95	2	9852056
Pubmed	Differential expression of retinoic acid receptors in normal and malignant esophageal tissues.	RARA RARB	2.21e-05	3	95	2	15255287
Pubmed	Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia.	RARA RARB	2.21e-05	3	95	2	17244680
Pubmed	The molecular and genetic dissection of the retinoid signalling pathway.	RARA RARB	2.21e-05	3	95	2	8276261
Pubmed	Requirement of retinoic acid receptor isotypes alpha, beta, and gamma during the initial steps of neural differentiation of PCC7 cells.	RARA RARB	2.21e-05	3	95	2	15831518
Pubmed	Genes involved in cell adhesion and signaling: a new repertoire of retinoic acid receptor target genes in mouse embryonic fibroblasts.	RARA RARB	2.21e-05	3	95	2	24357724
Pubmed	The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response.	NFE2L2 BRD4	2.21e-05	3	95	2	24763052
Pubmed	Regulation of retinoic acid receptor alpha by protein kinase C in B16 mouse melanoma cells.	RARA RARB	2.21e-05	3	95	2	12000751
Pubmed	Specificity of retinoid receptor gene expression in mouse cervical epithelia.	RARA RARB	2.21e-05	3	95	2	8156902
Pubmed	Immunohistochemical localization of the retinoic Acid receptors in human prostate.	RARA RARB	2.21e-05	3	95	2	12399530
Pubmed	Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion.	MFN2 CLEC16A	2.21e-05	3	95	2	35472764
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	GLMN FARSA KANK1 ARNT2 SPG11 CHD7 USP54 HUWE1 PUM1 SLC3A2	3.28e-05	733	95	10	34672954
Pubmed	Functional proteomics mapping of a human signaling pathway.	KANK1 RARB BRD4 HUWE1 PUM1 PRPF40A RYR2 SMAD1 SON	3.57e-05	591	95	9	15231748
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	FNDC3B DDX19A TCF7L2 EARS2 ZMIZ1 PUM1 PRPF40A NUP35	3.74e-05	457	95	8	32344865
Pubmed	A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart.	A1CF TCF7L2	4.41e-05	4	95	2	29394407
Pubmed	Association of peroxisome proliferator-activated receptors/retinoic acid receptors with renal diseases.	RARA RARB	4.41e-05	4	95	2	24050824
Pubmed	Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specific ligand.	RARA RARB	4.41e-05	4	95	2	8524212
Pubmed	Biosynthesis and function of all-trans- and 9-cis-retinoic acid in parathyroid cells.	RARA RARB	4.41e-05	4	95	2	9005841
Pubmed	Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled.	RARA RARB	4.41e-05	4	95	2	12093741
Pubmed	A conserved clathrin assembly motif essential for synaptic vesicle endocytosis.	AP2B1 SNAP91	4.41e-05	4	95	2	11102472
Pubmed	The retinoid receptors.	RARA RARB	4.41e-05	4	95	2	7967725
Pubmed	Mitochondrial fusion is essential for organelle function and cardiac homeostasis.	A1CF MFN2	4.41e-05	4	95	2	22052916
Pubmed	Identification of a retinoid receptor response element in the human aldehyde dehydrogenase-2 promoter.	RARA RARB	4.41e-05	4	95	2	14691372
Pubmed	The retinoic acid receptors RARalpha and RARgamma are required for inner ear development.	RARA RARB	4.41e-05	4	95	2	12464434
Pubmed	Limited specificity and large overlap of the functions of the mouse RAR gamma 1 and RAR gamma 2 isoforms.	RARA RARB	4.41e-05	4	95	2	9376317
Pubmed	Differential expression of genes encoding alpha, beta and gamma retinoic acid receptors and CRABP in the developing limbs of the mouse.	RARA RARB	4.41e-05	4	95	2	2556642
Pubmed	Retinoic acid signalling in the development of branchial arches.	RARA RARB	4.41e-05	4	95	2	15380252
Pubmed	Dimerization with retinoid X receptors and phosphorylation modulate the retinoic acid-induced degradation of retinoic acid receptors alpha and gamma through the ubiquitin-proteasome pathway.	RARA RARB	4.41e-05	4	95	2	10869350
Pubmed	HACE1: A novel repressor of RAR transcriptional activity.	RARA RARB	4.41e-05	4	95	2	19350571
Pubmed	Roles of retinoic acid receptors and of Hox genes in the patterning of the teeth and of the jaw skeleton.	RARA RARB	4.41e-05	4	95	2	7626396
Pubmed	Immunolocalization of enzymes, binding proteins, and receptors sufficient for retinoic acid synthesis and signaling during the hair cycle.	RARA RARB	4.41e-05	4	95	2	17363914
Pubmed	Nuclear GRP75 binds retinoic acid receptors to promote neuronal differentiation of neuroblastoma.	RARA RARB	4.41e-05	4	95	2	22022577
Pubmed	Circadian modulation of gene expression, but not glutamate uptake, in mouse and rat cortical astrocytes.	PER1 NPAS2	4.41e-05	4	95	2	19829696
Pubmed	Specific and redundant functions of retinoid X Receptor/Retinoic acid receptor heterodimers in differentiation, proliferation, and apoptosis of F9 embryonal carcinoma cells.	RARA RARB	4.41e-05	4	95	2	9348290
Pubmed	Retinoic acid regulates the human methionine sulfoxide reductase A (MSRA) gene via two distinct promoters.	RARA RARB	4.41e-05	4	95	2	18845237
Cytoband	Xp21.1	FAM47A FAM47C FAM47DP	5.06e-05	34	96	3	Xp21.1
Cytoband	22q13.33	NCAPH2 CHKB PPP6R2	7.09e-05	38	96	3	22q13.33
Cytoband	2q11.2	LMAN2L FER1L5 NPAS2	4.76e-04	72	96	3	2q11.2
Cytoband	Ensembl 112 genes in cytogenetic band chrXp21	FAM47A FAM47C FAM47DP	7.47e-04	84	96	3	chrXp21
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	SECISBP2L CACNA1A MAGI2 LMOD3 ST6GAL2 SNAP91 SOBP AP3B2 ARNT2 KIAA1549 ZMIZ1 ATP1A3 LRP1B RYR2 AHNAK2	8.89e-06	1106	94	15	M39071
Coexpression	BENPORATH_SOX2_TARGETS	TRIM16 CACNA1A FARSA KANK1 TCF7L2 PNMA1 UBE2T REST HUWE1 PUM1 ABTB2 SLC3A2	1.24e-05	734	94	12	M3835
Coexpression	BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	SECISBP2L TRIM16 TCF7L2 NFE2L2 BRD4 ZNF254 PER1 ZMIZ1 PUM1 ABTB2 SLC3A2 AHNAK2	3.78e-05	822	94	12	M6782
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	SECISBP2L TCF7L2 PSME4 WASF3 ARNT2 SPG11 BTAF1 ATP13A3 ZMIZ1 PUM1 CLEC16A SON	5.58e-05	856	94	12	M4500
Coexpression	GSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_UP	TRIM16 DOCK2 CDKL5 GGA2 AP2B1 SYNE1	7.64e-05	196	94	6	M7666
Coexpression	GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN	FNDC3B BRD4 MED14 ATP13A3 ZMIZ1 SLC3A2	8.08e-05	198	94	6	M5346
Coexpression	GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_DN	TREX1 FARSA MRS2 SYNE1 ZMIZ1 PRPF40A	8.30e-05	199	94	6	M5201
Coexpression	GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_UP	CACNA1A DDX19A RARA AP2B1 PER1 CHKB	8.54e-05	200	94	6	M7911
Coexpression	GSE14350_IL2RB_KO_VS_WT_TEFF_DN	INTS14 UBE2T TOR2A GBP2 CHD7 SLC3A2	8.54e-05	200	94	6	M3424
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000	KANK1 ARNT2 DAB1 MED14 KIAA1549 ATP13A3 ZMIZ1 HUWE1 PRPF40A	3.94e-05	379	92	9	gudmap_developingKidney_e15.5_1000_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000	RARB BRD4 ARNT2 MED14 ATP13A3 ZMIZ1 PUM1 RYR2 SON	4.45e-05	385	92	9	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
ToppCell	COVID-19-kidney-Epithelial_Doublet\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK2 CACNA1A LMOD3 KCNB1 ABCB5 RYR2	2.94e-07	124	96	6	d6f59ddb9b9df02b5201f23fa5fb78f3fd891ee9
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	FNDC3B KANK1 A1CF DAB1 PUM1 PPP6R2	3.04e-06	185	96	6	1d874608aa2062024323512f68889219471b2f00
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 NFE2L2 MYO3B DAB1 LRP1B ABTB2	3.13e-06	186	96	6	d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	KANK1 RARB PER1 PPP6R2 ABTB2 NPAS2	3.54e-06	190	96	6	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ST6GAL2 FRAS1 RARB IQCA1 LRP1B RYR2	3.65e-06	191	96	6	156b467187331ac6ca390d6ca861d9670bb7b956
ToppCell	(5)_Dendritic_cell-(53)_Lymphoid_DC\|(5)_Dendritic_cell / shred on Cell_type and subtype	ARNT2 DAB1 USP54 CHKB CLEC16A ABTB2	4.49e-06	198	96	6	548da5fa86f9756c503ed77bcdde55bc4d1a2726
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1A KCNB1 SNAP91 SYNE1 ATP1A3 RYR2	4.49e-06	198	96	6	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1A KCNB1 SNAP91 SYNE1 ATP1A3 RYR2	4.49e-06	198	96	6	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ST6GAL2 KANK1 SYNE1 ARNT2 DAB1 LRP1B	4.62e-06	199	96	6	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ST6GAL2 KANK1 SYNE1 ARNT2 DAB1 LRP1B	4.62e-06	199	96	6	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ST6GAL2 KANK1 SYNE1 ARNT2 DAB1 LRP1B	4.62e-06	199	96	6	e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CACNA1A KCNB1 SNAP91 SYNE1 ATP1A3 RYR2	4.76e-06	200	96	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KANK1 TCF7L2 CHD7 PRPF40A ABTB2	3.00e-05	166	96	5	a7ac5a414e3e2ff01f1c452c0a85048b17cba0b6
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1A A1CF SNAP91 AP3B2 ARNT2	3.27e-05	169	96	5	96a2aec9acf8a6f966973c035e5ade456cf47772
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 MYO3B DNAH6 LRP1B RYR2	3.27e-05	169	96	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	CV-Mild-7\|CV / Virus stimulation, Condition and Cluster	CDKL5 GLMN ZNF254 PPP6R2 ABTB2	3.36e-05	170	96	5	25ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCell	CV-Mild-7\|Mild / Virus stimulation, Condition and Cluster	CDKL5 GLMN ZNF254 PPP6R2 ABTB2	3.65e-05	173	96	5	c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCell	3'-Adult-LargeIntestine-Epithelial-Tuft-related-Microfold_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PNMA1 SNAP91 ARNT2 CD74 ALOX12B	4.65e-05	182	96	5	b4f347fb684f6840c166d7473f3f56389f69c14b
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAGI2 ST6GAL2 DAB1 ABTB2 RYR2	4.77e-05	183	96	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 NFE2L2 MYO3B NPAP1 ABTB2	4.77e-05	183	96	5	d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 NFE2L2 MYO3B LRP1B ABTB2	5.16e-05	186	96	5	08632045d499e61dd96ff29a5a9a208afe58dc58
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 KANK1 SOBP PUM1 PPP6R2	5.16e-05	186	96	5	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 KANK1 SOBP PUM1 PPP6R2	5.16e-05	186	96	5	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	PBMC-Mild-cDC_5\|Mild / Compartment, Disease Groups and Clusters	NFE2L2 BRD4 PER1 CD74 NCAPH2	5.29e-05	187	96	5	0afef5baf3752314dbfb024790347d5e51f9b84b
ToppCell	COVID-19-kidney-CD-PC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRAS1 MYO3B NPAP1 LRP1B ABTB2	5.43e-05	188	96	5	8f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 NFE2L2 MYO3B LRP1B ABTB2	5.43e-05	188	96	5	4154f4787483c7e076e87a187733a9f666742c3d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 NFE2L2 MYO3B LRP1B ABTB2	5.56e-05	189	96	5	90aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B FRAS1 KANK1 ARNT2 LRP1B	5.56e-05	189	96	5	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B FRAS1 KANK1 NFE2L2 ARNT2	5.56e-05	189	96	5	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 NFE2L2 MYO3B LRP1B ABTB2	5.70e-05	190	96	5	4836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 NFE2L2 MYO3B ABTB2 NPAS2	5.85e-05	191	96	5	96b78b4e819ea6052334bfcbc7abbf35897df885
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 IQCA1 NPAP1 ABTB2 NPAS2	5.99e-05	192	96	5	fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 IQCA1 NPAP1 ABTB2 NPAS2	5.99e-05	192	96	5	bae236c9f1fac77bce28d0a9cf090100d391ff77
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B FRAS1 MYO3B ARNT2 CLEC16A	6.14e-05	193	96	5	263d185af6ed80e639f864e4966268e0862c61dc
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 KANK1 A1CF SOBP DAB1	6.14e-05	193	96	5	503a979328c68b096680b71359a26f02fafdff35
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B FRAS1 MYO3B ARNT2 CLEC16A	6.14e-05	193	96	5	80e058c224749b5fe0ba3e944b48317c2371cb63
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B FRAS1 MYO3B ARNT2 CLEC16A	6.14e-05	193	96	5	b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO3B KIAA1549 CD74 ABTB2 NPAS2	6.30e-05	194	96	5	4579b4a44f7c731553a284843c296866027d7c0e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 KANK1 MYO3B ARNT2 ABTB2	6.30e-05	194	96	5	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 KANK1 MYO3B LRP1B ABTB2	6.45e-05	195	96	5	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A SLC43A2 KCNB1 HUWE1 SON	6.45e-05	195	96	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDKL5 ST6GAL2 KCNB1 RYR2 NPAS2	6.45e-05	195	96	5	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO3B KIAA1549 CD74 ABTB2 NPAS2	6.45e-05	195	96	5	3d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 KANK1 MYO3B ARNT2 ABTB2	6.61e-05	196	96	5	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Neuronal-CPNs\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	ST6GAL2 SNAP91 DAB1 ATP1A3 RYR2	6.61e-05	196	96	5	c9e7ac34993c873de4f198cdae77dcf099731532
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SECISBP2L IQCA1 CHD7 USP54 SON	6.77e-05	197	96	5	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-MYL4+_SMC\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PNMA1 DAB1 GBP2 PCARE AHNAK2	6.77e-05	197	96	5	4797f414330316e2ac2cf7cd2570d991877d7a38
ToppCell	control-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SLC43A2 FNDC3B PSME4 ATP13A3 PUM1	6.77e-05	197	96	5	df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1A SNAP91 SYNE1 ATP1A3 RYR2	6.93e-05	198	96	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	(08)_Brush+PNEC\|World / shred by cell type by condition	UBE2T ARNT2 DAB1 ZMIZ1 ALOX12B	7.10e-05	199	96	5	f2e33cb569c25fc2732722cac295647e9bd8738f
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FNDC3B RARB SYNE1 ATP13A3 RYR2	7.10e-05	199	96	5	8b86c69aaf60feff53aa782559cfece7342a23de
Drug	Alexidine dihydrochloride [22573-93-9]; Down 200; 6.8uM; MCF7; HT_HG-U133A	TCF7L2 MRS2 SFXN3 ZNF254 MFN2 PPP6R2 PRRC2A RYR2	1.32e-06	194	93	8	4721_DN
Drug	Antimycin A [1397-94-0]; Down 200; 7.2uM; MCF7; HT_HG-U133A	GGA2 A1CF LMAN2L BRD4 NCAPH2 REST RYR2	1.35e-05	191	93	7	2261_DN
Drug	fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	GGA2 RARA BRD4 ZNF254 MFN2 NCAPH2 RYR2	1.35e-05	191	93	7	5234_DN
Drug	Clotrimazole [23593-75-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A	GGA2 TCF7L2 SFXN3 MED14 ATP13A3 NCAPH2 PPP6R2	1.40e-05	192	93	7	6207_DN
Drug	Heptaminol hydrochloride [543-15-7]; Down 200; 22uM; HL60; HT_HG-U133A	A1CF PER1 MFN2 NCAPH2 PPP6R2 CLEC16A ENOX2	1.54e-05	195	93	7	1866_DN
Drug	Gemfibrozil [25812-30-0]; Up 200; 16uM; PC3; HT_HG-U133A	TCF7L2 SYNE1 WASF3 ARNT2 GBP2 REST PRRC2A	1.54e-05	195	93	7	2113_UP
Drug	Thiethylperazine malate [52239-63-1]; Down 200; 6uM; MCF7; HT_HG-U133A	GGA2 TCF7L2 MED14 CHD7 ATP13A3 NCAPH2 PPP6R2	1.65e-05	197	93	7	6232_DN
Drug	Ro 8-8717	RARA RARB	1.65e-05	2	93	2	CID006438148
Drug	Tamibarotene	RARA RARB	1.65e-05	2	93	2	DB04942
Drug	Laudanosine (R,S) [1699-51-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A	TCF7L2 RARA MED14 ATP13A3 NCAPH2 PPP6R2 PRRC2A	1.76e-05	199	93	7	7030_DN
Drug	LY 294002; Down 200; 10uM; PC3; HT_HG-U133A	FARSA RARA AP2B1 ZNF254 MFN2 PPP6R2 ABTB2	1.76e-05	199	93	7	1227_DN
Disease	calcium measurement	SECISBP2L SLC43A2 A1CF LMAN2L RARB RTL9 ZMIZ1 ATP1A3 FER1L5 LRP1B	3.23e-05	628	94	10	EFO_0004838
Disease	Left Ventricle Remodeling	TCF7L2 NFE2L2 MFN2	3.99e-05	21	94	3	C0600520
Disease	Ventricular Remodeling	TCF7L2 NFE2L2 MFN2	3.99e-05	21	94	3	C0600519
Disease	Alternating hemiplegia of childhood	CACNA1A ATP1A3	6.00e-05	4	94	2	C0338488
Disease	Neuralgia-Neuritis, Sciatic Nerve	RARA RARB	6.00e-05	4	94	2	C0751924
Disease	Sciatic Nerve Palsy	RARA RARB	6.00e-05	4	94	2	C0751925
Disease	Sciatic Neuropathy	RARA RARB	6.00e-05	4	94	2	C0149940
Disease	Lesion of Sciatic Nerve	RARA RARB	6.00e-05	4	94	2	C0154748
Disease	Sciatic Neuritis	RARA RARB	6.00e-05	4	94	2	C0242013
Disease	Hyperplasia	TCF7L2 NFE2L2 BRD4	9.68e-05	28	94	3	C0020507
Disease	platelet component distribution width	RARB AP2B1 SYNE1 WASF3 ATP13A3 ZMIZ1 CHKB PRRC2A NUP35 NPAS2	1.48e-04	755	94	10	EFO_0007984
Disease	Dystonia	CACNA1A TREX1 EARS2 ATP1A3	1.68e-04	86	94	4	C0013421
Disease	PR interval	MAGI2 FNDC3B RARB ABCB5 DAB1 ZMIZ1 CHKB RYR2	1.87e-04	495	94	8	EFO_0004462
Disease	familial hemiplegic migraine (implicated_via_orthology)	CACNA1A ATP1A3	2.09e-04	7	94	2	DOID:0060178 (implicated_via_orthology)
Disease	Abnormality of the face	BRD4 PUM1	3.56e-04	9	94	2	C4025871
Disease	epilepsy (is_implicated_in)	KCNB1 ATP1A3	3.56e-04	9	94	2	DOID:1826 (is_implicated_in)
Disease	eosinophil measurement	APMAP CHD7 ZMIZ1 CLEC16A	4.02e-04	108	94	4	EFO_0803540
Disease	alcohol consumption measurement	SECISBP2L CACNA1A MAGI2 ST6GAL2 TCF7L2 SNAP91 NFE2L2 WASF3 REST ATP1A3 CLEC16A NPAS2	5.80e-04	1242	94	12	EFO_0007878
Disease	age at first birth measurement	CACNA1A TCF7L2 RARB PRRC2A	5.98e-04	120	94	4	EFO_0009101
Disease	Malignant neoplasm of breast	FNDC3B RARA RARB SYNE1 MED14 PER1 MROH7 CD74 USP54 ZMIZ1 PRRC2A	6.18e-04	1074	94	11	C0006142
Disease	Seizures	CDKL5 TREX1 REST ZMIZ1 PUM1	6.77e-04	218	94	5	C0036572
Disease	RS-warfarin measurement	RARB SNAP91 IQCA1 LRP1B	7.62e-04	128	94	4	EFO_0803325
Disease	Bipolar Disorder	CACNA1A MAGI2 TCF7L2 LMAN2L SYNE1 ATP1A3 NPAS2	8.43e-04	477	94	7	C0005586
Disease	2-oxo-hept-3-ene-1,7-dioate hydratase activity	ATP13A3 SMAD1	8.91e-04	14	94	2	C1150929
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	MAGI2 TCF7L2 RARB DAB1 BTAF1 CHD7 REST FAM186B RYR2	1.04e-03	801	94	9	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	cutaneous Leishmaniasis	TCF7L2 CHKB	1.17e-03	16	94	2	EFO_0005046
Disease	wheezing	MAGI2 RARB SPG11	1.19e-03	65	94	3	EFO_0009715
Disease	photoreceptor cell layer thickness measurement	TCF7L2 RARB CHD7 GRK1	1.31e-03	148	94	4	EFO_0803370
Disease	muscular dystrophy (is_implicated_in)	SYNE1 CHKB	1.32e-03	17	94	2	DOID:9884 (is_implicated_in)
Disease	Familial primary pulmonary hypertension	ATP13A3 SMAD1	1.32e-03	17	94	2	C0340543
Disease	unipolar depression, bipolar disorder	TCF7L2 LMAN2L SYNE1 WASF3	1.58e-03	156	94	4	EFO_0003761, MONDO_0004985
Disease	psoriasis, type 2 diabetes mellitus	GLMN TCF7L2 ZMIZ1	1.79e-03	75	94	3	EFO_0000676, MONDO_0005148
Disease	Colorectal Carcinoma	CDKL5 TCF7L2 RARB SYNE1 ABCB5 NPAP1 PER1 ZMIZ1	1.82e-03	702	94	8	C0009402
Disease	acetate measurement	APMAP SPG11	1.84e-03	20	94	2	EFO_0010112
Disease	corneal hysteresis	FNDC3B TCF7L2	1.84e-03	20	94	2	EFO_0010066
Disease	epilepsy (implicated_via_orthology)	CACNA1A ATP1A3 CHKB LRP1B	1.86e-03	163	94	4	DOID:1826 (implicated_via_orthology)
Disease	bipolar disorder	DOCK2 LMAN2L KCNB1 SNAP91 SYNE1 ZMIZ1 HUWE1	2.49e-03	577	94	7	MONDO_0004985
Disease	airway responsiveness measurement	RARB SOBP	2.65e-03	24	94	2	EFO_0006897
Disease	West Syndrome	MAGI2 CDKL5	2.65e-03	24	94	2	C0037769
Disease	arachidonic acid measurement	CACNA1A DAB1	2.87e-03	25	94	2	EFO_0006808
Disease	Ataxia	CACNA1A PUM1	2.87e-03	25	94	2	C0004134
Disease	severe acute respiratory syndrome, COVID-19	MAGI2 MYO3B ARNT2 DAB1 LRP1B ABTB2	3.10e-03	447	94	6	EFO_0000694, MONDO_0100096
Disease	Intellectual Disability	TREX1 LMAN2L SYNE1 BRD4 ZMIZ1 PUM1	3.10e-03	447	94	6	C3714756
Disease	Kallmann Syndrome	ARNT2 CHD7	3.10e-03	26	94	2	C0162809

Protein segments in the cluster

Peptide	Gene	Start	Entry
TDPGPMLAIPAMATN	CACNA1A	1101	O00555
LPLNTLGPVMKMEPL	AP2B1	786	P63010
LPGMELTPMNPVTLK	A1CF	426	Q9NQ94
EEPPAPPLTSMQMQL	BRD4	916	O60885
PGDVMVIPLNGTIMP	ATP13A3	291	Q9H7F0
CLPLMPLVLGEMSDN	ABCB5	61	Q2M3G0
MYPNLGEDMPPDLLL	FAM47DP	131	A6NHR8
GAMMLLESPIDPQPL	APMAP	56	Q9HDC9
LGDLLMPTMAPAGQP	SNAP91	721	O60641
LPPSPMAMIRDSGAI	FAM186B	371	Q8IYM0
DLPPTGLPEMNLLEM	CHKB	201	Q9Y259
NPAAVLPLMLPGMAG	CHD7	2791	Q9P2D1
REEEMIFLGMNPPPL	IQCA1	231	Q86XH1
PPVGELMAPVFMSEN	AP3B2	966	Q13367
TEVFQDMLPMPGDPT	ARNT2	681	Q9HBZ2
MAQVPMLNLLPSPGL	MROH7	41	Q68CQ1
EIPGSMPPLIQEMLE	RARA	401	P10276
EIPGSMPPLIQEMLE	RARB	401	P10826
EPMLTPSLPMVSLQD	KIAA1549	191	Q9HCM3
LSQPIQPMMPGSCDA	NPAS2	676	Q99743
PMPVLLMGQAVLHPS	NPAS2	726	Q99743
LAMYPNLGEDMPPDL	FAM47C	131	Q5HY64
TEVAQMGPAPMEPAQ	REST	696	Q13127
IPHQDGMLPLISTMP	FRAS1	3341	Q86XX4
GIPLEPSDKMDALMP	LRP1B	1891	Q9NZR2
PEDPANSMVPPLAIM	MAGI2	516	Q86UL8
VMAPDPSLPVGMIQK	LMOD3	41	Q0VAK6
PLFLAMMGPLQGDPL	SLC43A2	501	Q8N370
GQPILPDFDPALGMM	ENOX2	56	Q16206
PPESDIIMMEDLPGL	PER1	736	O15534
IIMMEDLPGLAPGPA	PER1	741	O15534
MMDLELPPPGLPSQQ	NFE2L2	1	Q16236
LGRQLEAPLPPMMAS	MRS2	396	Q9HD23
ESLENPQPQAPLGMM	KANK1	806	Q14678
LPSVDNMKLPEMTAP	LMAN2L	291	Q9H0V9
MAPEINLPGPMSLID	GBP2	1	P32456
MPPAVISQMLLLDNP	GGA2	561	Q9UJY4
PPPIMGGVVRDLSMS	HUWE1	1356	Q7Z6Z7
MPPLPQGSLTQEEFM	MFN2	586	O95140
DMMDSLISQLQPPPQ	MED14	991	O60244
PLDPMEHVGMEPLQF	PUM1	346	Q14671
MQPALPPGVNSMDVA	PRPF40A	121	O75400
FGQELPMDMELPSPE	DNAH6	4041	Q9C0G6
PMDMELPSPEDGVLV	DNAH6	4046	Q9C0G6
FMEGDPSPLLPVLGM	KCNB1	676	Q14721
PGMVGPILEMTLIPE	DOCK2	1086	Q92608
MPLPAAMFQGPLTPL	DAB1	406	O75553
LMPLEAGIPDPPNMS	BTAF1	1216	O14981
MMTDQIPLELPPLLN	FNDC3B	6	Q53EP0
PPLLNGEVAMMPHLV	FNDC3B	16	Q53EP0
SNLMMSLFEPGPEPL	INTS14	346	Q96SY0
AAALPGQPMEAPVML	SLC3A2	476	P08195
MMPIAIQLSQTPGPD	ALOX12B	351	O75342
VGLMSMIDPPRAAVP	ATP1A3	576	P13637
LAMYPNLGEDMPPDL	FAM47A	131	Q5JRC9
TPLLMQALPMGALPQ	CD74	111	P04233
ALPMMLAEPPQNLIA	DDX19A	121	Q9NUU7
RQLEAGMLMPPFIPD	GRK1	461	Q15835
MLELLEEMPNGVPPE	CDKL5	96	O76039
TPGPEMPAEMLNYIL	PNMA1	131	Q8ND90
GLSDLMSNPVPMPEV	RYR2	4401	Q92736
VPLGPIMAVTAAPAM	PPP6R2	926	O75170
NLEHLPPPPMEVLMD	PCARE	826	A6NGG8
VEPQGPALGSEPMML	NUP35	6	Q8NFH5
VMEMRSPLLAGGSPP	NUP35	61	Q8NFH5
VSGEEIPNMPPEMQL	GLMN	541	Q92990
PDAEAMSPALMTALP	RTL9	341	Q8NET4
AIPAMAIPPLIMDTL	SFXN3	236	Q9BWM7
MPPGLMEVLRPFLGS	TOR2A	166	Q8N2E6
GVFRPEMLLPMGLPE	FARSA	436	Q9Y285
TPGEEPPLMQEITAM	SYNE1	5286	Q8NF91
NTVLPEPQMGLPDVM	FER1L5	686	A0AVI2
PSGAPAQQMLLPMVD	PRRC2A	1971	P48634
PNPPSSGFIGILIMM	ST6GAL2	431	Q96JF0
PDTFMIPMALPNDNG	SECISBP2L	26	Q93073
PVQLPVSGPELAAMM	HERC2P3	581	Q9BVR0
DMSPEGPQPPMILLQ	HERC2P3	1081	Q9BVR0
GLPIPLMSGKRMPDE	NPAP1	291	Q9NZP6
QQGPPVAEMMLALGP	EARS2	496	Q5JPH6
MMAPPLPSEINRGDV	SMAD1	246	Q15797
LNNERPFMLLPPLME	ABTB2	411	Q8N961
EVMPAQSMPLPTELG	AHNAK2	386	Q8IVF2
PLLPMALVAPDEMEK	NCAPH2	146	Q6IBW4
LMMDASILLPPTGTP	CLEC16A	631	Q2KHT3
LPMLLVPVPAEAMGQ	SPG11	26	Q96JI7
MPPGLMEVLRPFLGS	TOR2A	166	Q5JU69
MALPSPQVLMGLPAL	ZNF132	1	P52740
MEEKPSGPIPDMLAT	ZNF414	1	Q96IQ9
MMNFGLPSLAPLVPP	SOBP	506	A7XYQ1
LSMMPPPPALLLAEA	TCF7L2	546	Q9NQB0
PMAPADYGMLPAQII	WASF3	321	Q9UPY6
IQLLMSEPNPDDPLM	UBE2T	111	Q9NPD8
PVMPKEMVPLGDSNS	TEX13C	696	A0A0J9YWL9
EGPTHMLPLLMRALP	PSME4	476	Q14997
MLPLLMRALPGVDPN	PSME4	481	Q14997
MAELDLMAPGPLPRA	TRIM16	1	O95361
MGSQALPPGPMQTLI	TREX1	1	Q9NSU2
LPPGPMQTLIFFDME	TREX1	6	Q9NSU2
MELPGPPATSMPELQ	SON	381	P18583
MVPGQAQPQSPEMLL	SIGLEC11	1	Q96RL6
PSSPGLLMVGEDMQP	nan	211	A6NL46
MPGPPRSLEMGLLTF	ZNF254	1	O75437
PMVGVPMFADQPDNI	UGT2A2	396	P0DTE5
PNVMEMIAALGPGPS	ZMIZ1	856	Q9ULJ6
LSPDVLMPTMAGEPN	USP54	1481	Q70EL1
LMPTMAGEPNRLPGT	USP54	1486	Q70EL1
NPMMLGLESLPDPTD	MYO3B	11	Q8WXR4