Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	store-operated calcium channel activity	TRPC7 TRPC6 ORAI3	5.55e-05	12	129	3	GO:0015279
GeneOntologyCellularComponent	RAVE complex	DMXL2 DMXL1	1.20e-04	3	133	2	GO:0043291
MousePheno	abnormal placental labyrinth villi morphology	NCOA6 LLGL2 ERVFRD-1	1.88e-05	8	99	3	MP:0011522
Domain	Rav1p_C	DMXL2 DMXL1	4.37e-05	2	124	2	IPR022033
Domain	Rav1p_C	DMXL2 DMXL1	4.37e-05	2	124	2	PF12234
Domain	-	NLRP11 LRWD1 PRAMEF10 VASN LRSAM1 NLRP1 LINGO3 SKP2 LINGO1 LRRC36	5.66e-05	321	124	10	3.80.10.10
Domain	L_dom-like	NLRP11 LRWD1 PRAMEF10 VASN LRSAM1 NLRP1 LINGO3 SKP2 LINGO1 LRRC36	6.77e-05	328	124	10	IPR032675
Domain	Leu-rich_rpt	NLRP11 LRWD1 VASN LRSAM1 NLRP1 LINGO3 SKP2 LINGO1 LRRC36	8.28e-05	271	124	9	IPR001611
Domain	LRR_1	LRWD1 VASN LRSAM1 NLRP1 LINGO3 SKP2 LINGO1 LRRC36	1.08e-04	219	124	8	PF00560
Domain	DUF4195	ZNF280D ZNF280C	2.60e-04	4	124	2	IPR025243
Domain	DUF4195	ZNF280D ZNF280C	2.60e-04	4	124	2	PF13836
Domain	RCC1	RCBTB2 RCBTB1 HERC6	3.00e-04	20	124	3	PF00415
Domain	RCC1_1	RCBTB2 RCBTB1 HERC6	3.48e-04	21	124	3	PS00625
Domain	RCC1_2	RCBTB2 RCBTB1 HERC6	3.48e-04	21	124	3	PS00626
Domain	RCC1_3	RCBTB2 RCBTB1 HERC6	3.48e-04	21	124	3	PS50012
Domain	LRR	LRWD1 VASN LRSAM1 NLRP1 LINGO3 LINGO1 LRRC36	3.92e-04	201	124	7	PS51450
Domain	-	RCBTB2 RCBTB1 HERC6	4.01e-04	22	124	3	2.130.10.30
Domain	Reg_chr_condens	RCBTB2 RCBTB1 HERC6	4.01e-04	22	124	3	IPR000408
Domain	Autophagy-rel_C	ATG2A VPS13B	4.32e-04	5	124	2	IPR015412
Domain	ATG_C	ATG2A VPS13B	4.32e-04	5	124	2	PF09333
Domain	RCC1/BLIP-II	RCBTB2 RCBTB1 HERC6	4.59e-04	23	124	3	IPR009091
Domain	TRP_2	TRPC7 TRPC6	6.45e-04	6	124	2	PF08344
Domain	TRP_dom	TRPC7 TRPC6	6.45e-04	6	124	2	IPR013555
Domain	TRPC_channel	TRPC7 TRPC6	8.98e-04	7	124	2	IPR002153
Domain	Chorein_N	ATG2A VPS13B	1.19e-03	8	124	2	PF12624
Domain	VPS13_N	ATG2A VPS13B	1.19e-03	8	124	2	IPR026854
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	DMXL2 MBOAT7 TRPM7 DHX57 ATG2A SLC39A10 DENND4C DMXL1 SEMA4C SCAP AKAP11 HEATR5B AKAP1 VPS13B	2.03e-08	504	141	14	34432599
Pubmed	The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons.	TRPC7 TRPM7 TRPC6	7.67e-06	10	141	3	27177420
Pubmed	High glucose level promotes migration behavior of breast cancer cells through zinc and its transporters.	SLC39A10 SLC39A6	1.63e-05	2	141	2	24587242
Pubmed	Moderate zinc deficiency reduces testicular Zip6 and Zip10 abundance and impairs spermatogenesis in mice.	SLC39A10 SLC39A6	1.63e-05	2	141	2	21248196
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	1.63e-05	2	141	2	11687802
Pubmed	Expression of CLLD7 and CHC1L Proteins in Oral Epithelial Dysplasia in a Group of Thai Patients.	RCBTB2 RCBTB1	1.63e-05	2	141	2	38679985
Pubmed	DDX27 regulates oral squamous cell carcinoma development through targeting CSE1L.	DDX27 CSE1L	1.63e-05	2	141	2	38301874
Pubmed	Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration.	SLC39A10 SLC39A6	1.63e-05	2	141	2	27274087
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	1.63e-05	2	141	2	34910522
Pubmed	N-glycosylation of SCAP exacerbates hepatocellular inflammation and lipid accumulation via ACSS2-mediated histone H3K27 acetylation.	ACSS2 SCAP	1.63e-05	2	141	2	38591127
Pubmed	Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II.	TRPC7 TRPC6	1.63e-05	2	141	2	23529130
Pubmed	PLC-mediated PI(4,5)P2 hydrolysis regulates activation and inactivation of TRPC6/7 channels.	TRPC7 TRPC6	1.63e-05	2	141	2	24470487
Pubmed	Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.	RNF213 HUWE1 SKP2 CCNF HERC6	2.58e-05	85	141	5	19028597
Pubmed	The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis.	SLC39A10 SLC39A6	4.88e-05	3	141	2	32797246
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	4.88e-05	3	141	2	30801007
Pubmed	SIPAR negatively regulates STAT3 signaling and inhibits progression of melanoma.	FAM220A FAM220BP	4.88e-05	3	141	2	23917203
Pubmed	Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries.	TRPC7 TRPC6	4.88e-05	3	141	2	28526717
Pubmed	LRRN6A/LERN1 (leucine-rich repeat neuronal protein 1), a novel gene with enriched expression in limbic system and neocortex.	LINGO3 LINGO1	4.88e-05	3	141	2	14686891
Pubmed	The Retinal Basis of Light Aversion in Neonatal Mice.	TRPC7 TRPC6	4.88e-05	3	141	2	35396331
Pubmed	IKKalpha controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression.	SKP2 CHUK	4.88e-05	3	141	2	16902410
Pubmed	Unique alternative translation from two open reading frames on Acpin1 mRNA yields an acrosomal protein and a salivary-gland-specific protein.	FAM220A FAM220BP	4.88e-05	3	141	2	19659802
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TET2 CNKSR1 DMXL2 TRPM7 LRSAM1 ASH1L CHD9 HUWE1 DDX27 DSCAML1 ANKRD54 CHUK NELL2 RCBTB1 MTUS2 SNX5	6.94e-05	1285	141	16	35914814
Pubmed	Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.	STRC STRCP1	9.74e-05	4	141	2	18849963
Pubmed	Expression of the Lingo/LERN gene family during mouse embryogenesis.	LINGO3 LINGO1	9.74e-05	4	141	2	18297755
Pubmed	A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition.	SLC39A10 SLC39A6	9.74e-05	4	141	2	28098160
Pubmed	Prognostic values of F-box members in breast cancer: an online database analysis and literature review.	SKP2 CCNF	9.74e-05	4	141	2	30341246
Pubmed	Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits.	TRPC7 TRPC6	9.74e-05	4	141	2	30017393
Pubmed	Pulsatile atheroprone shear stress affects the expression of transient receptor potential channels in human endothelial cells.	TRPM7 TRPC6	9.74e-05	4	141	2	22566504
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	VWA3A MTF2 TRPC6 GBE1 ITPRID1 DENND4C ABITRAM STARD9 SHOC1 HERC6 VPS13B	1.18e-04	686	141	11	29987050
Pubmed	Mapping the expression of transient receptor potential channels across murine placental development.	TRPC7 TRPM7 TRPC6	1.24e-04	24	141	3	33884443
Pubmed	International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.	TRPC7 TRPM7 TRPC6	1.41e-04	25	141	3	16382100
Pubmed	A genetically determined insertion/deletion related polymorphism in human T cell receptor beta chain (TCRB) includes functional variable gene segments.	TRBV4-3 TRBV4-2	1.62e-04	5	141	2	7931073
Pubmed	TRPC channels are necessary mediators of pathologic cardiac hypertrophy.	TRPC7 TRPC6	1.62e-04	5	141	2	20351294
Pubmed	Intrinsic phototransduction persists in melanopsin-expressing ganglion cells lacking diacylglycerol-sensitive TRPC subunits.	TRPC7 TRPC6	1.62e-04	5	141	2	21261756
Pubmed	Dual inhibition of endothelial miR-92a-3p and miR-489-3p reduces renal injury-associated atherosclerosis.	FAM220A FAM220BP	1.62e-04	5	141	2	30731284
Pubmed	Molecular and electrophysiological characterization of transient receptor potential ion channels in the primary murine megakaryocyte.	TRPM7 TRPC6	1.62e-04	5	141	2	16857711
Pubmed	Nuclear termination of STAT3 signaling through SIPAR (STAT3-Interacting Protein As a Repressor)-dependent recruitment of T cell tyrosine phosphatase TC-PTP.	FAM220A FAM220BP	1.62e-04	5	141	2	26026268
Pubmed	An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.	STRC STRCP1	1.62e-04	5	141	2	24920589
Pubmed	Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.	OR8H2 OR8H3 OR5H1	1.78e-04	27	141	3	32061665
Pubmed	An introduction to TRP channels.	TRPC7 TRPM7 TRPC6	1.78e-04	27	141	3	16460286
Pubmed	Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins.	CH25H SCAP	2.42e-04	6	141	2	32514064
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TET2 NCOA6 ZNF280C ATG2A WDR37 MAST4 MRC2 AKAP11 NUP188	3.23e-04	529	141	9	14621295
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	NCOA6 DMXL2 DSCAML1 SCAP AKAP11 UNC80	3.25e-04	225	141	6	12168954
Pubmed	A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.	TRPC7 TRPM7 TRPC6	3.26e-04	33	141	3	19834762
Pubmed	MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC.	TRPC7 TRPC6	3.38e-04	7	141	2	15757897
Pubmed	Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs.	TRPC7 TRPC6	3.38e-04	7	141	2	38109525
Pubmed	Synaptic, transcriptional and chromatin genes disrupted in autism.	ASH1L DHX57	3.38e-04	7	141	2	25363760
Pubmed	RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways.	TRPC7 TRPC6	3.38e-04	7	141	2	32350291
Pubmed	TRPC absence induces pro-inflammatory macrophages and gut microbe disorder, sensitizing mice to colitis.	TRPC7 TRPC6	3.38e-04	7	141	2	36592529
Pubmed	Functional role of TRPC proteins in vivo: lessons from TRPC-deficient mouse models.	TRPC7 TRPC6	3.38e-04	7	141	2	15336983
Pubmed	TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer.	TRPC7 TRPC6	3.38e-04	7	141	2	38835669
Pubmed	Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival.	TRPM7 ERVFRD-1	3.38e-04	7	141	2	27991852
Pubmed	Subunit composition, molecular environment, and activation of native TRPC channels encoded by their interactomes.	TRPC7 TRPC6	3.38e-04	7	141	2	36257322
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CHD9 HUWE1 DSCAML1 MTUS2	4.44e-04	87	141	4	12465718
Pubmed	The LZT proteins; the LIV-1 subfamily of zinc transporters.	SLC39A10 SLC39A6	4.50e-04	8	141	2	12659941
Pubmed	ATP-citrate lyase promotes axonal transport across species.	ACSS2 FOXG1	4.50e-04	8	141	2	34620845
Pubmed	Subunit composition of mammalian transient receptor potential channels in living cells.	TRPC7 TRPC6	4.50e-04	8	141	2	12032305
Pubmed	Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.	STRC STRCP1	4.50e-04	8	141	2	21165971
Pubmed	Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels.	TRPC7 TRPC6	4.50e-04	8	141	2	25471572
Pubmed	Association of immunophilins with mammalian TRPC channels.	TRPC7 TRPC6	4.50e-04	8	141	2	15199065
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR8H2 OR8H3 OR8D2 OR5H15 OR51G2 OR1L8 OR5H1	4.95e-04	340	141	7	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR8H2 OR8H3 OR8D2 OR5H15 OR51G2 OR1L8 OR5H1	4.95e-04	340	141	7	11802173
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	TRPC7 TRPM7 TRPC6	4.96e-04	38	141	3	30786075
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR8H2 OR8H3 OR8D2 OR5H15 OR51G2 OR1L8 OR5H1	5.22e-04	343	141	7	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR8H2 OR8H3 OR8D2 OR5H15 OR51G2 OR1L8 OR5H1	5.49e-04	346	141	7	14611657
Pubmed	Anchoring and scaffold proteins for kinases and phosphatases.	AKAP11 AKAP1	5.77e-04	9	141	2	9238861
Pubmed	Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels.	TRPC7 TRPC6	5.77e-04	9	141	2	11290752
Pubmed	Cellular subtype distribution and developmental regulation of TRPC channel members in the mouse dorsal root ganglion.	TRPC7 TRPC6	5.77e-04	9	141	2	17480026
Pubmed	Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.	NCOA6 SCAP NUP188	6.21e-04	41	141	3	8724849
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	OR8H2 ASH1L RNF213 CHD9 SIPA1 WDR37 TRIM24 ANKRD54 NELL2 ZFHX4 NUP188 UNC5D UNC80	6.39e-04	1116	141	13	31753913
Pubmed	Fbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradation.	HIPK2 SKP2	7.19e-04	10	141	2	18765672
Pubmed	Heterogeneous distribution of TRPC proteins in the embryonic cortex.	TRPC7 TRPC6	7.19e-04	10	141	2	18989690
Pubmed	ZNF70, a novel ILDR2-interacting protein, contributes to the regulation of HES1 gene expression.	ILDR2 MBOAT7	7.19e-04	10	141	2	27353377
Pubmed	Concordance of two multiple analytical approaches demonstrate that interaction between BMI and ADIPOQ haplotypes is a determinant of LDL cholesterol in a general French population.	ENPP1 SCAP	7.19e-04	10	141	2	20186155
Pubmed	HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα.	HUWE1 CHUK	7.19e-04	10	141	2	30217973
Pubmed	AKAP mediated signal transduction.	AKAP11 AKAP1	7.19e-04	10	141	2	11807172
Pubmed	Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors.	ASH1L FOXG1	7.19e-04	10	141	2	34145365
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	MBOAT7 MARS1 RNF213 TRIM24 CSE1L MOCS1	7.24e-04	262	141	6	36880596
Pubmed	Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.	TRPC7 TRPM7 TRPC6	7.65e-04	44	141	3	19322198
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TET2 ZNF280D RNF213 HUWE1	7.79e-04	101	141	4	10997877
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	LRSAM1 RCBTB2 SKP2 FASTK RCBTB1 ASB4 HERC6	8.40e-04	372	141	7	22939624
Pubmed	Cyclin F-Dependent Degradation of RBPJ Inhibits IDH1R132H-Mediated Tumorigenesis.	SKP2 CCNF	8.76e-04	11	141	2	30254149
Pubmed	Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.	STRC STRCP1	8.76e-04	11	141	2	31448880
Pubmed	Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.	STRC STRCP1	8.76e-04	11	141	2	31776257
Pubmed	SKP2 attenuates NF-κB signaling by mediating IKKβ degradation through autophagy.	SKP2 CHUK	8.76e-04	11	141	2	29474632
Pubmed	SPOP targets oncogenic protein ZBTB3 for destruction to suppress endometrial cancer.	HIPK2 TRIM24	1.05e-03	12	141	2	31911863
Pubmed	ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.	NCOA6 ACO2 CHD9 SLC22A6	1.18e-03	113	141	4	34474245
Pubmed	Melanopsin signalling in mammalian iris and retina.	TRPC7 TRPC6	1.24e-03	13	141	2	22051675
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	MBOAT7 VASN ENPP1 RNF213 SLC39A10 DMXL1 NELL2 SCAP MRC2 FHOD1 SLC39A6 AKAP1 SNX5	1.24e-03	1201	141	13	35696571
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	DSCAML1 SEMA4C UNC5D	1.25e-03	52	141	3	26633812
Pubmed	The genetics of NOD-like receptors in Crohn's disease.	NLRP11 NLRP1	1.44e-03	14	141	2	20403135
Pubmed	NALPs: a novel protein family involved in inflammation.	NLRP11 NLRP1	1.44e-03	14	141	2	12563287
Pubmed	Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.	ASH1L DHX57	1.44e-03	14	141	2	28263302
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TET2 ZNF280D HUWE1 TRIM24 DENND4C ZFHX4 AKAP1	1.64e-03	418	141	7	34709266
Pubmed	Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.	TRIM51 CHUK	1.66e-03	15	141	2	19703589
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	ZNF280D ZNF280C HIPK2 TRIM24	1.72e-03	125	141	4	32891193
Pubmed	Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.	ASH1L ZFHX4	1.89e-03	16	141	2	16096065
Pubmed	Ablation of Zfhx4 results in early postnatal lethality by disrupting the respiratory center in mice.	ZFHX4 FOXG1	1.89e-03	16	141	2	33475140
Pubmed	The ubiquitin conjugating enzyme, UbcM2, engages in novel interactions with components of cullin-3 based E3 ligases.	RCBTB2 RCBTB1	1.89e-03	16	141	2	19256485
Pubmed	The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics.	LRWD1 DDX27	2.13e-03	17	141	2	20813266
Cytoband	7q32-q34	HIPK2 TRIM24	9.50e-06	2	142	2	7q32-q34
GeneFamily	WD repeat domain containing	DMXL2 LRWD1 WDR37 DMXL1 LLGL2 SCAP WDR87	2.70e-04	262	87	7	362
GeneFamily	Transient receptor potential cation channels	TRPC7 TRPM7 TRPC6	3.23e-04	28	87	3	249
GeneFamily	Olfactory receptors, family 8	OR8H2 OR8H3 OR8D2	1.69e-03	49	87	3	155
Coexpression	WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP	TET2 DMXL2 ZNF280D FAM220A RNF213 RCBTB2 ITGB7 SHISA7 DMXL1 PARP10 AFG1L	6.21e-06	392	135	11	M2131
Coexpression	GSE41867_DAY6_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_DN	NCOA6 LRWD1 ZNF280C HUWE1 SLC25A51 DENND4C MEMO1 VPS13B	9.67e-06	200	135	8	M9490
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000	ILDR2 DMXL2 ZNF280D TRPM7 MTF2 ANKRD10 ASH1L RNF213 CHD9 HUWE1 WDR37 TRIM24 SKP2 DMXL1 MAST4 KANSL1 ZFHX4 ASB4	7.86e-07	804	122	18	gudmap_developingGonad_e12.5_ovary_1000
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA3A ILDR2 DSCAML1 ZFHX4 PKHD1 USH2A UNC80	7.99e-07	160	141	7	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA3A ILDR2 DSCAML1 ZFHX4 PKHD1 USH2A UNC80	7.99e-07	160	141	7	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSPOP DSCAML1 ZFHX4 PKHD1 USH2A UNC5D UNC80	2.03e-06	184	141	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSPOP DSCAML1 ZFHX4 PKHD1 USH2A UNC5D UNC80	2.03e-06	184	141	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSPOP DSCAML1 ZFHX4 PKHD1 USH2A UNC5D UNC80	2.03e-06	184	141	7	2b19a8c5f823e00812908b23e66bb4e563278aff
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	1.90e-05	2	129	2	DOID:0110471 (implicated_via_orthology)
Disease	puberty onset measurement	NCOA6 TRPC7 SLC28A3 KANSL1 AKAP1	2.28e-04	125	129	5	EFO_0005677
Disease	pulse pressure measurement	TET2 TRPM7 VASN RNF213 SLC39A10 SIPA1 MEI1 ZNF831 SSPOP DENND4C ZNF716 CEP120 KANSL1 ZFHX4 MRC2	1.14e-03	1392	129	15	EFO_0005763
Disease	nicotine dependence (implicated_via_orthology)	TRPC7 TRPC6	1.22e-03	12	129	2	DOID:0050742 (implicated_via_orthology)
Disease	cannabis dependence measurement	ACO2 MEI1 PKHD1	1.22e-03	48	129	3	EFO_0008457
Disease	pneumonia, COVID-19	NELL2 UNC5D VPS13B UNC80	1.55e-03	113	129	4	EFO_0003106, MONDO_0100096
Disease	urate measurement, bone density	DDX12P B3GNTL1 TRPC6 GBE1 CASC2 MAST4 LINGO1 ALG8 USH2A	1.64e-03	619	129	9	EFO_0003923, EFO_0004531
Disease	phoneme awareness	DDX27 CSE1L	1.67e-03	14	129	2	EFO_0021812
Disease	Anilide use measurement	HCP5 KANSL1	1.92e-03	15	129	2	EFO_0009938
Disease	retinal vasculature measurement	ACO2 HIPK2 GBE1 DSCAML1 CHRNB4 CSE1L LINGO1 MOCS1	2.02e-03	517	129	8	EFO_0010554
Disease	lung small cell carcinoma (is_marker_for)	SKP2 CHRNB4	2.19e-03	16	129	2	DOID:5409 (is_marker_for)
Disease	coronary artery disease	TET2 NCOA6 TRPM7 RNF213 SIPA1 ZNF831 SKP2 CHRNB4 DMXL1 CEP120 MAST4 PKHD1 SHOC1	2.24e-03	1194	129	13	EFO_0001645
Disease	reaction time measurement	TET2 OR10J6P GBE1 NLRP1 SLC28A3 CSE1L KANSL1 PKHD1 AFG1L	2.47e-03	658	129	9	EFO_0008393
Disease	androgenetic alopecia	SLC28A3 MEMO1 KANSL1 AKAP1	2.81e-03	133	129	4	EFO_0004191
Disease	hippocampal tail volume	ITPRID1 MAST4	3.09e-03	19	129	2	EFO_0009398
Disease	lung cancer (is_implicated_in)	NCOA6 TRPC7 CHRNB4	4.22e-03	74	129	3	DOID:1324 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
PALSHCSQLTTFNFH	PRAMEF33	371	A0A0G2JMD5
FQLQCHIESTHTPHE	ZNF280D	371	Q6N043
VTSVCVLNVHHRSPS	CHRNB4	311	P30926
SKVAVPSTIHCDHLI	ACO2	116	Q99798
LETFCSEIGTNHTHL	FAM200B	366	P0CF97
KPNISAHHISLASCL	AKAP1	451	Q92667
AHHISLASCLALTTP	AKAP1	456	Q92667
LLSEKLTSSCSPHHI	ASH1L	1781	Q9NR48
ATLCSLLQQTPHAHL	ANKRD10	36	Q9NXR5
HLAACTNHVPVITTL	ANKRD54	181	Q6NXT1
HTALHFCTTPSSILC	ASB4	141	Q9Y574
HSSLHVCICISSFPN	FAM106A	96	Q4KMX7
ACLHSILSATLHVYP	FAM220A	186	Q7Z4H9
CLHSILSATLHACPE	FAM220BP	181	B1ANY3
EICNPEQITSFITHH	ABCA6	716	Q8N139
CSASTPISSLFLHQH	AFG1L	406	Q8WV93
HSNRICVITLAESHP	ABITRAM	41	Q9NX38
FPHSHTFSSTALTCV	AKAP11	1066	Q9UKA4
CHFHIAASINPATDI	DMXL2	356	Q8TDJ6
LACHSVLPLLLTSSH	DMXL2	656	Q8TDJ6
PSVISHLFSHRCLTI	ACSS2	686	Q9NR19
LVAPANSLVHAFTCH	DMXL1	2871	Q9Y485
IDHLHNCPSFHLSSI	DDX27	351	Q96GQ7
PTVITILHTHLFSCS	ATG2A	1106	Q2TAZ0
TQLACAHSELHELFP	C17orf113	581	A0A1B0GUU1
IHSCIISPSLTEAHV	CCDC60	136	Q8IWA6
VLQVCSEHTSHSAHP	MTUS2	266	Q5JR59
QLCHTPHIDSSVIDS	MTF2	131	Q9Y483
QSVILPHLTHFSCTD	RCBTB1	316	Q8NDN9
SVILPHLTHFSCTDD	RCBTB2	341	O95199
SNIVHHIYCDTIPLS	OR5H15	171	A6NDH6
STCLLPHIEAVSNIH	ORAI3	116	Q9BRQ5
ATLCFSPAHETHLFT	LRWD1	396	Q9UFC0
TACSHQTLLTPFALT	ARHGEF28	111	Q8N1W1
PSFDIHTIHVCLHLA	FASTK	151	Q14296
SNVIHHFFCDTSPIL	OR8H2	171	Q8N162
HSSLHVCICISSFPN	FAM106C	96	P0CH98
SHTVSHYFCDILPLL	OR8D2	171	Q9GZM6
VECDSLVPVNTSHHS	HIPK2	981	Q9H2X6
AITCSHHVSNIPLKL	LLGL2	386	Q6P1M3
ALDCPESHQITLSHS	NELL2	376	Q99435
ESSGFCPHTNHSLLV	ITPRID1	621	Q6ZRS4
IVHTNHLTSLLPKSC	LRSAM1	61	Q6UWE0
DILHEPTCQISHLSL	NLRP11	711	P59045
TSAEHDHSLSCVVTP	CHUK	686	O15111
THHLTAAALAASVPC	FOXG1	376	P55316
PDTFHLTHDASLSKC	LRRC36	296	Q1X8D7
ICHPLHYVSILTNTV	OR51G2	131	Q8NGK0
HSTVQTILTVHLPFC	OR4Q2	156	P0C623
CTVHINIHIPLSATS	ODR4	181	Q5SWX8
GQIHSVCSETPSHFV	PEX3	331	P56589
LQPHSLESLHCLYET	NLRP1	711	Q9C000
CHSPHQEALSVFLLL	HERC6	471	Q8IVU3
ERDHPTSITCHNILS	HERC6	976	Q8IVU3
TNCTLPHRSLDVEHT	KANSL1	206	Q7Z3B3
HLTCLNLSHNPISTV	LINGO3	271	P0C6S8
LTLFTCGPHTLHSLV	MBOAT7	41	Q96N66
TSCAVVLHSPSAHFT	MRC2	1076	Q9UBG0
CNLTSIPTEALSHLH	LINGO1	201	Q96FE5
FILPHRTDNSESCVH	ENPP1	856	P22413
CSVLAFVLDHLLPHT	HUWE1	2106	Q7Z6Z7
HELLLPSLCDSSHAS	HCP5	66	Q6MZN7
VTSQLIPLCHHVALS	MOCS1	546	Q9NZB8
SNIIHHFFCDTSPIL	OR8H3	171	Q8N146
ERCQSPFSFHHVLSL	ITGB7	221	P26010
SAHCITAVLVHSPAK	MEI1	301	Q5TIA1
SNIVHHIYCDTIPLS	OR5H1	171	A6NKK0
HSNELCSSLVHPELS	NCOA6	1551	Q14686
PHCHQSSLSREVAVV	C6orf132	771	Q5T0Z8
EHVLSPHSQFNCSPI	CHD9	91	Q3L8U1
ANHLVHTLCPDSITI	GBE1	396	Q04446
HVNLSSLVPSLCVHL	HEATR5B	1061	Q9P2D3
SLVPSLCVHLCSSHL	HEATR5B	1066	Q9P2D3
SVLSLDSDSHTQPCH	CCNF	726	P41002
EVAAHTSCLQSITPH	LINC01599	81	Q8WXQ3
AVPATSHHFCFSIDL	CEP120	446	Q8N960
QSFCTGVSLHHPTLI	DSCAML1	1696	Q8TD84
QTFHLDTADHPCVIT	CASC2	66	Q6XLA1
CVIHPLHSSLSSEEQ	DHX57	881	Q6P158
VHLCTFITSFHPSLF	C1orf112	421	Q9NSG2
ASQPRDHISHCLLSA	DDX12P	926	Q92771
RTHSFENVSCHLPDS	DENND4C	1096	Q5VZ89
LTPHLCTNSLHLNVV	MARF1	246	Q9Y4F3
TPDELHFLSKHFCTT	MAST4	321	O15021
HHLCSLVLQTRPESS	FHOD1	861	Q9Y613
VISFSFPFLLHTCSH	CT62	111	P0C5K7
SPNCSLRAESLVHVH	SCAP	261	Q12770
TLQNFTAAIPTHHCR	SLC22A6	36	Q4U2R8
STSIAVFCHELPHEL	SLC39A10	701	Q9ULF5
TLLGCHPLTTLTFHV	CH25H	191	O95992
VVTNCSAEHSHPALS	MFNG	106	O00587
FHDTQALPTHLITCE	PARP10	991	Q53GL7
HHVPLSRCALSSVDI	MEMO1	81	Q9Y316
DSNVIHHFLCDLSPV	OR1L8	171	Q8NGR8
TSIFTLPFCHTVVGH	OR10J6P	161	Q8NGY7
AVFTPHQFLLSACTH	USH2A	2111	O75445
ALLSPCTTHSQRHAF	SSPOP	741	A2VEC9
SCLLHKHVSAPEFAT	SLC25A51	106	Q9H1U9
QLESCLEHKSHSSPI	SHOC1	406	Q5VXU9
CPTTIRSHFQHVFLV	SIPA1	446	Q96FS4
TLSCSRSFHNLSHLP	SHISA7	291	A6NL88
LLEHTVSAESIPCHL	SAMD10	41	Q9BYL1
AHVNTSQELSFLHPC	SPATA31E1	816	Q6ZUB1
ATEAFCLHSVHPETI	PKHD1	4056	P08F94
ILSSTPVDINCHHVL	SLC28A3	611	Q9HAS3
KHTTCREFTNTSLHP	STARD9	2186	Q9P2P6
VLVPSDNFTITFHHC	IL9R	111	Q01113
TDLVLPCHLSSNLAH	SEMA4C	571	Q9C0C4
LFCHIHPVSVVLSSL	MRGPRX2	256	Q96LB1
NFSIHLLCQHTKPAT	STRC	366	Q7RTU9
LSTSVAVFCHELPHE	SLC39A6	626	Q13433
HHPQAATHCVLETTI	B3GNTL1	231	Q67FW5
CLLIPTYHSTDFEVH	ALG8	26	Q9BVK2
EEHSHLCPLTSESSL	CNKSR1	701	Q969H4
EALPHLQINCSHFTT	SKP2	381	Q13309
QVHLVSFQCSPHSTP	RNF213	2801	Q63HN8
KVFHLSCHVPTLTNF	TRIM24	846	O15164
LQLHLTHLHSVSPDC	ZFHX4	1216	Q86UP3
IHLAQSLHKLSTACP	CSE1L	926	P55060
ALPHVLHCTATLLSN	UNC80	81	Q8N2C7
HELSAPSVHPTCVFT	LINC00052	111	Q96N35
TPLFHFHISTCLKTQ	ERVFRD-1	281	P60508
QPTVLRCHFSTSSHQ	ILDR2	36	Q71H61
CHVTTANRPSLDAHL	TUT1	21	Q9H6E5
DTHCSLFTTSPLVVQ	TRIM51	386	Q9BSJ1
HPVTCSHFTQDLQSE	ZNF716	86	A6NP11
DLHSSHTPSLQFLCI	NUP188	751	Q5SRE5
PALSHCSQLTTFNFH	PRAMEF10	371	O60809
HTAACLHSLALEEPT	SNX5	246	Q9Y5X3
FALTIPHCADVSSEH	UNC5D	616	Q6UXZ4
SHVTLASPEETRCHF	VASN	316	Q6EMK4
LTHCCTHPTQRLVVT	WDR37	326	Q9Y2I8
ECPNSSHLFLHLHTL	TRBV4-3	86	A0A589
YFIVSQPSLLLSCHH	VPS13B	1956	Q7Z7G8
NFSIHLLCQHTKPAT	STRCP1	366	A6NGW2
FQLQCHIESTHTPHE	ZNF280C	366	Q8ND82
PCFSELISHQNIHTE	ZNF597	351	Q96LX8
FSHDVTPIILAAHCQ	TRPC6	216	Q9Y210
FPHHDIATSVAAVCI	ZNF831	1481	Q5JPB2
ATNELSCEITHPSHT	TET2	256	Q6N021
ECPNSSHLFLHLHTL	TRBV4-2	86	A0A539
PLASILSSCHLTHLI	WDR87	511	Q6ZQQ6
LTHIDHSLSRQNCPF	MARS1	121	P56192
FTDCHRTSIPVHSKQ	TRPM7	1481	Q96QT4
SCSVTDSLVDFPHHV	WWC3	181	Q9ULE0
LSHVQALQHSSPCEA	VWA3A	351	A6NCI4
ASAKHCSIFPSVEIH	VWA3A	896	A6NCI4
FSHDITPIILAAHCQ	TRPC7	161	Q9HCX4