Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncarbon-sulfur lyase activity

CENPVL2 CENPVL3 CENPVL1

4.01e-0516853GO:0016846
HumanPhenoDisplacement of the urethral meatus

FLNA SMG8 DIS3L2 EFNB1 USB1 RIPPLY2 ARX REST NEB SPEN NIPBL JMJD1C

1.01e-063973012HP:0100627
HumanPhenoAbnormal male urethral meatus morphology

FLNA SMG8 DIS3L2 EFNB1 USB1 RIPPLY2 ARX REST NEB SPEN NIPBL JMJD1C

1.07e-063993012HP:0032076
HumanPhenoAbnormality of the lower urinary tract

BPTF FLNA SMG8 DIS3L2 EFNB1 SBF1 USB1 MAPT RIPPLY2 TRPS1 ARX GIGYF2 REST NEB SPEN NIPBL JMJD1C

2.95e-069373017HP:0010936
HumanPhenoHypospadias

FLNA SMG8 DIS3L2 EFNB1 RIPPLY2 ARX REST NEB SPEN NIPBL JMJD1C

4.77e-063773011HP:0000047
HumanPhenoAbnormality of the urethra

FLNA SMG8 DIS3L2 EFNB1 USB1 RIPPLY2 ARX REST NEB SPEN NIPBL JMJD1C

5.45e-064653012HP:0000795
HumanPhenoLong upper lip

DIS3L2 TRPS1 ARX

1.01e-058303HP:0011341
HumanPhenoAsymmetric growth

BPTF DIS3L2 EFNB1 REST SPEN

6.47e-0575305HP:0100555
HumanPhenoAbnormal penis morphology

FLNA SMG8 CENPT DIS3L2 EFNB1 USB1 RIPPLY2 ARX REST NEB SPEN NIPBL JMJD1C

8.40e-057123013HP:0000036
HumanPhenoLong philtrum

FLNA SMG8 USB1 RIPPLY2 TRPS1 ARX NEB SPEN NIPBL JMJD1C

1.04e-044293010HP:0000343
HumanPhenoAbnormality of the diaphragm

FLNA DIS3L2 EFNB1 RIPPLY2 NEB NIPBL

1.39e-04141306HP:0000775
HumanPhenoScoliosis

BPTF FLNA MIA3 CENPT EFNB1 SBF1 USB1 MAPT RIPPLY2 TRPS1 ARX DDRGK1 NEB SPEN ATP2B1 JMJD1C

1.69e-0411223016HP:0002650
HumanPhenoConductive hearing impairment

DNAAF3 BPTF FLNA RP1L1 TRPS1 SPEN NIPBL JMJD1C CCDC40

1.97e-04373309HP:0000405
HumanPhenoHemihypotrophy of lower limb

BPTF EFNB1

2.00e-044302HP:0200053
HumanPhenoCongenital diaphragmatic hernia

FLNA DIS3L2 EFNB1 RIPPLY2 NIPBL

2.54e-04100305HP:0000776
HumanPhenoFunctional abnormality of the middle ear

DNAAF3 BPTF FLNA RP1L1 TRPS1 SPEN NIPBL JMJD1C CCDC40

2.56e-04386309HP:0011452
DomainGRANINS_2

CHGA CHGB

1.86e-052812PS00423
DomainChromogranin_AB

CHGA CHGB

1.86e-052812IPR001819
DomainGRANINS_1

CHGA CHGB

5.56e-053812PS00422
DomainGranin

CHGA CHGB

5.56e-053812IPR001990
DomainChromogranin_CS

CHGA CHGB

5.56e-053812IPR018054
DomainGranin

CHGA CHGB

5.56e-053812PF01271
Pubmed

Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow.

CENPVL2 CENPVL3 TEX13D CENPVL1

5.72e-10688427250503
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BPTF FLNA MAPT ZFP91 MKI67 GIGYF2 ZNF217 ITPRID2 REST GPATCH8 SPEN MIER1 NIPBL FKBP5

9.15e-09774881415302935
Pubmed

Cell organization, growth, and neural and cardiac development require αII-spectrin.

ANK2 MAPT MKI67

1.85e-061088322159418
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

BPTF TRPS1 SPEN NIPBL JMJD1C

2.30e-068388528794006
Pubmed

Direct regulation of intestinal fate by Notch.

MKI67 CHGA CHGB

2.55e-061188316107537
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

BPTF UBE2O CENPT ZFP91 MKI67 GPATCH8 SPEN MIER1 NIPBL JMJD1C

3.29e-06608881036089195
Pubmed

CAMSAP1 breaks the homeostatic microtubule network to instruct neuronal polarity.

MAPT MKI67 CAMSAP2

3.39e-061288332839317
Pubmed

Arx polyalanine expansion in mice leads to reduced pancreatic α-cell specification and increased α-cell death.

ARX MKI67 CHGA

5.58e-061488324236044
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

BPTF FLNA UBE2O SBF1 MKI67 BYSL GIGYF2 SPEN NIPBL TASOR2

6.16e-06653881022586326
Pubmed

Diagnostic caveats of immunoreactivity for Ki67 and chromogranin A in hyalinizing trabecular tumour of the thyroid.

MKI67 CHGA

6.33e-06288225012947
Pubmed

Utility of chromogranin B compared with chromogranin A as a biomarker in Japanese patients with pancreatic neuroendocrine tumors.

CHGA CHGB

6.33e-06288228334992
Pubmed

Combining the lack of chromogranins with chronic L-DOPA treatment affects motor activity in mice.

CHGA CHGB

6.33e-06288231900665
Pubmed

Antibacterial activity of glycosylated and phosphorylated chromogranin A-derived peptide 173-194 from bovine adrenal medullary chromaffin granules.

CHGA CHGB

6.33e-0628828910482
Pubmed

Different chromogranin immunoreactivity between prion and a-beta amyloid plaque.

CHGA CHGB

6.33e-06288212692477
Pubmed

The biochemical utility of chromogranin A, chromogranin B and cocaine- and amphetamine-regulated transcript for neuroendocrine neoplasia.

CHGA CHGB

6.33e-06288223939195
Pubmed

Chromogranins A and B as regulators of vesicle cargo and exocytosis.

CHGA CHGB

6.33e-06288221046455
Pubmed

Mice lacking chromogranins exhibit increased aggressive and depression-like behaviour.

CHGA CHGB

6.33e-06288225257107
Pubmed

Chromogranins A and B are key proteins in amine accumulation, but the catecholamine secretory pathway is conserved without them.

CHGA CHGB

6.33e-06288221990378
Pubmed

Routine measurement of plasma chromogranin B has limited clinical utility in the management of patients with neuroendocrine tumours.

CHGA CHGB

6.33e-06288226608723
Pubmed

Chromogranin A and chromogranin B in noninvasive and invasive breast carcinoma.

CHGA CHGB

6.33e-06288212165659
Pubmed

The Plasma Membrane Ca2+-ATPase, a Molecular Target for Tau-induced Cytosolic Calcium Dysregulation.

MAPT ATP2B1

6.33e-06288235469971
Pubmed

Direct and Indirect Effects of Filamin A on Tau Pathology in Neuronal Cells.

FLNA MAPT

6.33e-06288236399251
Pubmed

The functional role of chromogranins in exocytosis.

CHGA CHGB

6.33e-06288222415354
Pubmed

Chromogranin B-induced secretory granule biogenesis: comparison with the similar role of chromogranin A.

CHGA CHGB

6.33e-06288212902350
Pubmed

Dense-core vesicle biogenesis and exocytosis in neurons lacking chromogranins A and B.

CHGA CHGB

6.33e-06288229178418
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

MKI67 GIGYF2 ZNF217 SPEN CAMSAP2 JMJD1C

7.64e-0618488632908313
Pubmed

A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs.

CHGA REST CHGB

8.56e-061688335577801
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

ARFGEF3 VPS13D MIA3 UBE2O AKAP11 CAMSAP2

1.58e-0520988636779422
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

FLNA CENPT MKI67 GPATCH8 MIER1 NIPBL

1.62e-0521088616565220
Pubmed

Increased fecal levels of chromogranin A, chromogranin B, and secretoneurin in collagenous colitis.

CHGA CHGB

1.90e-05388223423580
Pubmed

Presence of chromogranin-derived antimicrobial peptides in plasma during coronary artery bypass surgery and evidence of an immune origin of these peptides.

CHGA CHGB

1.90e-05388212091348
Pubmed

Chromogranin peptides in amyotrophic lateral sclerosis.

CHGA CHGB

1.90e-05388218721831
Pubmed

Serum levels of chromogranins and secretogranins correlate with the progress and severity of Parkinson's disease.

CHGA CHGB

1.90e-05388230887724
Pubmed

Cellular expression and specific intragranular localization of chromogranin A, chromogranin B, and synaptophysin during ontogeny of pancreatic islet cells: an ultrastructural study.

CHGA CHGB

1.90e-05388212826904
Pubmed

Expression of trophinin, tastin, and bystin by trophoblast and endometrial cells in human placenta.

TROAP BYSL

1.90e-05388210026108
Pubmed

Receptor for advanced glycation end products (RAGE) signaling induces CREB-dependent chromogranin expression during neuronal differentiation.

CHGA CHGB

1.90e-05388212167613
Pubmed

PKA compartmentalization via AKAP220 and AKAP12 contributes to endothelial barrier regulation.

AKAP11 AKAP12

1.90e-05388225188285
Pubmed

EphrinB1 interacts with CNK1 and promotes cell migration through c-Jun N-terminal kinase (JNK) activation.

CNKSR1 EFNB1

1.90e-05388224825906
Pubmed

Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3.

ARX MKI67 CHGA CHGB

2.03e-056388425053427
Pubmed

βlinc1 encodes a long noncoding RNA that regulates islet β-cell formation and function.

ARX CHGA CHGB

2.33e-052288326944677
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

FLNA UBE2O ANK2 MKI67 DDRGK1 GIGYF2 CAMSAP2 NIPBL SNX1 AKAP12 AHNAK2

2.40e-05934881133916271
Pubmed

Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation.

ARX MKI67 CHGA

3.05e-052488323852729
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

DLGAP2 MIA3 UBE2O PDE4B ANK2 SBF1 GIGYF2 CAMSAP2 UNC79 NIPBL AKAP12

3.18e-05963881128671696
Pubmed

Tshz1 Regulates Pancreatic β-Cell Maturation.

ARX MKI67 CHGA

3.46e-052588325918232
Pubmed

Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis.

CHGA CHGB

3.79e-05488216369483
Pubmed

Trophoblast cell activation by trophinin ligation is implicated in human embryo implantation.

TROAP BYSL

3.79e-05488217360433
Pubmed

Immunohistochemical and biochemical studies with region-specific antibodies to chromogranins A and B and secretogranins II and III in neuroendocrine tumors.

CHGA CHGB

3.79e-05488221046454
Pubmed

Nebulin regulates thin filament length, contractility, and Z-disk structure in vivo.

FLNA NEB

3.79e-05488216902413
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

MIA3 UBE2O MKI67 GIGYF2 JMJD1C AHNAK2

5.70e-0526388634702444
Pubmed

Human transcription factor protein interaction networks.

BPTF UBE2O TRPS1 ZFP91 MKI67 GIGYF2 ZNF217 GPATCH8 SPEN MIER1 NIPBL JMJD1C ZNF691

6.15e-051429881335140242
Pubmed

UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.

FLNA MIA3 ANK2 MAPT GIGYF2 AKAP12

6.19e-0526788633417871
Pubmed

Trps1 Regulates Development of Craniofacial Skeleton and Is Required for the Initiation of Palatal Shelves Fusion.

TRPS1 MKI67

6.30e-05588231130868
Pubmed

FKBP51 modulates hippocampal size and function in post-translational regulation of Parkin.

MAPT FKBP5

6.30e-05588235244772
Pubmed

A cytoplasmic protein, bystin, interacts with trophinin, tastin, and cytokeratin and may be involved in trophinin-mediated cell adhesion between trophoblast and endometrial epithelial cells.

TROAP BYSL

6.30e-0558829560222
Pubmed

Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.

MAPT FKBP5

6.30e-05588223999428
Pubmed

Nrf2 Transcriptional Activity Governs Intestine Development.

MKI67 CHGA

6.30e-05588235682851
Pubmed

The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.

MAPT FKBP5

6.30e-05588220071522
Pubmed

Altered PTEN, ATRX, CHGA, CHGB, and TP53 expression are associated with aggressive VHL-associated pancreatic neuroendocrine tumors.

CHGA CHGB

6.30e-05588223361940
Pubmed

Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality.

MKI67 MAPK6

6.30e-05588219805361
Pubmed

FilaminA and Formin2 regulate skeletal, muscular, and intestinal formation through mesenchymal progenitor proliferation.

FLNA MKI67

6.30e-05588229240780
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ARFGEF3 VPS13D SBF1 MAPT GIGYF2 AKAP11 ITPRID2 CAMSAP2 ATP2B1 AHNAK2

6.49e-05861881036931259
Pubmed

The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.

BPTF MKI67 NIPBL TASOR2

6.94e-058688437253089
Pubmed

Identification of Redox and Glucose-Dependent Txnip Protein Interactions.

FLNA UBE2O JMJD1C

7.36e-053288327437069
Pubmed

Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas.

MKI67 CHGA CHGB

8.85e-053488326771085
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

FLNA MIA3 PDE4B TRH PPP4R2 GPATCH8 USF2 RPE ATP2B1 MIER1 AKAP12

9.17e-051084881111544199
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

MIA3 UBE2O EFNB1 ANK2 SBF1 BYSL DDRGK1 AKAP11 ITPRID2 ATP2B1 FKBP5 SNX1 AKAP12

9.18e-051487881333957083
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

FLNA SBF1 MAPT ZFP91 MKI67 GIGYF2 SPEN AKAP12 AHNAK2

9.23e-0572488936232890
Pubmed

Foxl1-deficient mice exhibit aberrant epithelial cell positioning resulting from dysregulated EphB/EphrinB expression in the small intestine.

EFNB1 MKI67

9.43e-05688216469829
Pubmed

Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex.

MAPT FKBP5

9.43e-05688230382094
Pubmed

Dispersion of chromogranin/secretogranin secretory protein family loci in mammalian genomes.

CHGA CHGB

9.43e-0568828617499
Pubmed

Frat is dispensable for canonical Wnt signaling in mammals.

EFNB1 MKI67

9.43e-05688215681612
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

FLNA TRPS1 GIGYF2 ZNF217 RBBP8NL JMJD1C S100PBP

9.47e-0541888734709266
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

FLNA VPS13D MIA3 DDRGK1 GIGYF2 SNX1 AKAP12 AHNAK2

9.85e-0556888837774976
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

SMG8 DIS3L2 OGFR DDRGK1 AKAP11

1.05e-0418388531932471
Pubmed

β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development.

ARX MKI67 CHGB

1.05e-043688326901059
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

BPTF FLNA PPP4R2 ZFP91 MKI67 ZNF217 USF2 SPEN NIPBL JMJD1C FKBP5

1.07e-041103881134189442
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

FLNA MKI67 CDADC1 MIER1 JMJD1C AHNAK2

1.13e-0429888630737378
Pubmed

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

EFNB1 MKI67 DDRGK1 JMJD1C AKAP12

1.28e-0419188531177093
Pubmed

S-adenosyl-L-methionine supplementation alleviates damaged intestinal epithelium and inflammatory infiltration caused by Mat2a deficiency.

MKI67 CHGA

1.32e-04788236975381
Pubmed

Trps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosis.

TRPS1 MKI67

1.32e-04788223133399
Pubmed

Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets.

ARX MKI67 CHGA

1.34e-043988328576773
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

BPTF FLNA CENPT MKI67 BYSL GIGYF2 SPEN NIPBL JMJD1C TASOR2

1.50e-04954881036373674
Pubmed

T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis.

MKI67 CHGA

1.75e-04888221383188
Pubmed

RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis.

RNF186 EFNB1

1.75e-04888233280498
Pubmed

Cloning, chromosomal mapping and expression pattern of the mouse Brca2 gene.

CHGA CHGB

1.75e-0488829063750
Pubmed

REST is a major negative regulator of endocrine differentiation during pancreas organogenesis.

MKI67 REST

1.75e-04888234385258
Pubmed

Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors.

MKI67 CHGA CHGB

1.80e-044388324227653
Pubmed

Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.

KIAA1210 ITPRID2 SPEN NIPBL

1.80e-0411088437219487
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

DLGAP2 FLNA ANK2 MKI67 PCDHA11 SPEN

1.93e-0432988617474147
Pubmed

Tagging genes with cassette-exchange sites.

BPTF MKI67 GIGYF2 REST GPATCH8 USF2

2.13e-0433588615741177
Pubmed

Congenital Diaphragmatic Hernia Overview

EFNB1 RIPPLY2 NIPBL

2.20e-044688320301533
Pubmed

Integrated Proteomics-Based Physical and Functional Mapping of AXL Kinase Signaling Pathways and Inhibitors Define Its Role in Cell Migration.

FLNA SNX1 AKAP12

2.20e-044688335022314
Pubmed

Characterization of the developing small intestine in the absence of either GATA4 or GATA6.

MKI67 CHGA

2.25e-04988225495347
Pubmed

Anchoring and scaffold proteins for kinases and phosphatases.

AKAP11 AKAP12

2.25e-0498829238861
Pubmed

Reexpression of oncoprotein MafB in proliferative β-cells and Men1 insulinomas in mouse.

ARX MKI67

2.25e-04988222120711
Pubmed

Expression analysis of the Islet-1 gene in the developing and adult gastrointestinal tract.

MKI67 CHGA

2.25e-04988221220053
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

FLNA MIA3 EFNB1 MKI67 DDRGK1 GPATCH8 CENPVL1 ATP2B1 JMJD1C TMUB2 ZNF691

2.27e-041203881129180619
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

BPTF FLNA TROAP OGFR MKI67 ITPRID2 AKAP12

2.63e-0449488726831064
Pubmed

Interaction network of human early embryonic transcription factors.

BPTF TRPS1 MKI67 ZNF217 SPEN NIPBL

2.74e-0435188638297188
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

BPTF FLNA ANK2 DDRGK1 CC2D1B MAPK6 NEB SPEN CAMSAP2 ATP2B1 NIPBL TASOR2

2.75e-041442881235575683
InteractionNUP43 interactions

BPTF FLNA CENPT ZFP91 MKI67 BYSL ITPRID2 GPATCH8 SPEN NIPBL JMJD1C TASOR2 AHNAK2

2.06e-066258513int:NUP43
InteractionTLE3 interactions

CCNF FLNA RIPPLY2 TRPS1 ZNF217 GPATCH8 SPEN RPE NIPBL FKBP5

4.09e-063768510int:TLE3
InteractionMAGED2 interactions

CCNF UBE2O OGFR ZFP91 DDRGK1 GIGYF2 MAPK6 FKBP5

8.61e-06243858int:MAGED2
InteractionDDX17 interactions

CCNF UBE2O MAPT BYSL DDRGK1 REST SPEN NIPBL FKBP5 AHNAK2

1.22e-054268510int:DDX17
InteractionRCOR1 interactions

FLNA TRPS1 MKI67 GIGYF2 ZNF217 REST SPEN MIER1 JMJD1C S100PBP

4.32e-054948510int:RCOR1
InteractionSRSF6 interactions

CCNF BPTF UBE2O DIS3L2 MAPT MKI67 DDRGK1 REST GPATCH8 SPEN

5.02e-055038510int:SRSF6
InteractionDNM3 interactions

EFNB1 SCN2B MKI67 RPE SNX1

5.36e-0596855int:DNM3
InteractionPRKACA interactions

ARFGEF3 PDE4B SBF1 MAPT DDRGK1 AKAP11 RPE ATP2B1 FKBP5 AKAP12

6.53e-055198510int:PRKACA
InteractionTOMM20 interactions

CCNF VPS13D MIA3 UBE2O MAPT DDRGK1 MAPK6

6.98e-05240857int:TOMM20
InteractionNCAPH2 interactions

CCNF BPTF SMG8 EFNB1 GIGYF2 TASOR2

8.05e-05169856int:NCAPH2
InteractionPHLPP1 interactions

FLNA EFNB1 GIGYF2 NEB JMJD1C FKBP5 SNX1 AHNAK2

8.14e-05333858int:PHLPP1
CytobandXp11.22

CENPVL2 CENPVL3 CENPVL1

1.57e-0454883Xp11.22
GeneFamilyGranins

CHGA CHGB

1.68e-048452925
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

ARFGEF3 MAPT MKI67 AKAP11

1.05e-03181454694
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

AKAP11 AKAP12

2.36e-0329452396
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

BPTF FLNA PDE4B TOX TRPS1 AKAP11 ZNF217 REST GPATCH8 USF2 SPEN IL18R1 MIER1 NIPBL JMJD1C FKBP5 LAX1

4.25e-0614928417M40023
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HOMTN

ARFGEF3 ANK2 RIPPLY2 CHGA MAPK6 ATP2B1 UNC79 SNX1 AHNAK2

4.40e-06389849M39073
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_INTERM_NEUROENDOCRINE_CELL

ARFGEF3 PRUNE2 ANK2 TOX CHGA CHGB UNC79

2.50e-05268847M45696
CoexpressionGSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_UP

MIA3 PDE4B GPATCH8 SPEN ATP2B1 NIPBL

3.61e-05192846M8272
CoexpressionGSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN

BPTF AKAP11 ITPRID2 GPATCH8 USF2 SPEN

4.29e-05198846M6128
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

BPTF SMG8 UBE2O CENPT EFNB1 PPP4R2 ZFP91 ARX MKI67 GPATCH8 RPE

2.22e-055958411Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#2_top-relative-expression-ranked_500

TRPS1 ZFP91 GIGYF2 ATP2B1

4.94e-0551844gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k2
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARFGEF3 PRUNE2 DLGAP2 FAM153B ANK2 CHGA CHGB UNC79

3.87e-09188888c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellwk_20-22-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 ANK2 RIPPLY2 CHGA CHGB RBBP8NL UNC79

4.96e-08171887b7cddb8f726a43fb8a37f3e67a3f722e2178fd7a
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARFGEF3 PRUNE2 DLGAP2 ANK2 CHGA CHGB UNC79

8.82e-08186887b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellwk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 ANK2 RIPPLY2 ARX CHGA CHGB UNC79

1.02e-07190887b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CNKSR1 PDE4B PPIP5K1 IL18R1 KIAA1614 AHNAK2

6.27e-071548868dc8f02534c3ebda30bf9e702e36d0c53d89e5a5
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 FAM153B ARX CHGA CHGB UNC79

9.39e-071658864b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 RNF186 RIPPLY2 CHGA CHGB UNC79

1.12e-0617088698d13dbd76a826e47d55553f9d11f71c043b573e
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOX ARX CHGA CHGB IL18R1 LAX1

1.28e-06174886ecdff386d7f0bc57c170a2c1f4deae5ba7e431b5
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIAA1210 RNF186 ANK2 RIPPLY2 CHGA CHGB

1.56e-061808865286e66ff6b7154390b3e9c189704a71d56bc89c
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIAA1210 RNF186 ANK2 RIPPLY2 CHGA CHGB

1.56e-061808862b6b295b5c21b829828afae9ab4c3eb9233f6f45
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIAA1210 RNF186 ANK2 RIPPLY2 CHGA CHGB

1.56e-06180886bf587387145a2b5e83766fbccf76eecc6d5e8241
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIAA1210 RNF186 ANK2 RIPPLY2 CHGA CHGB

1.77e-0618488692314fcdb74c0a1262c9334c774819a2a49ba454
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPS1 ATP2B1 MIER1 NIPBL JMJD1C AKAP12

1.83e-061858867adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 PRUNE2 RIPPLY2 CHGA CHGB UNC79

1.88e-06186886fcabebdfbf1b1dbb35ce2b3c53a60d2b1aed8e6c
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 PRUNE2 MIA3 ANK2 CHGA CHGB

2.20e-061918863387b95a3f2445c672d407922fdce3a91eabaef8
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 PRUNE2 MIA3 ANK2 CHGA CHGB

2.20e-06191886a251b134f67a0a1ef3a42f50042f128a17f20b22
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate|6m / Sample Type, Dataset, Time_group, and Cell type.

BPTF REST NEB SPEN NIPBL JMJD1C

2.86e-062008867c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARFGEF3 DLGAP2 CHGA CHGB UNC79

1.60e-051598857747cef94c55144fddcd024a7495318357f1351b
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHGB NEB CAMSAP2 ZNF691 LAX1

2.15e-05169885d18b823836ca6fba79a2d2f10cb9966fa2623af2
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHGB NEB CAMSAP2 ZNF691 LAX1

2.15e-05169885befb9b1618ea30fbf8983bcc493853da53b809c3
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ARX CHGA CHGB UNC79

2.21e-051708856a98f47f8c2b5b15e09169bd82eff1e6bf76e5a6
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CCNF SBF1 TROAP MKI67 BRME1

2.34e-051728856fcc16f1067672967ecbcdfdc727649ae9891dd9
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

CCNF ARFGEF3 TROAP MKI67 BRME1

2.54e-05175885fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

CCNF ARFGEF3 TROAP MKI67 BRME1

2.54e-0517588536c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRUNE2 FLNA FNDC1 FAM153B SCN2B

2.75e-051788858ec2a25dda96c9cc9c2904b6cb18f75a293f4969
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRUNE2 FLNA FNDC1 FAM153B SCN2B

2.75e-051788856c91331196696e0cf239d105f458e3230659fa38
ToppCell15-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

ARFGEF3 PRUNE2 RIPPLY2 CHGA CHGB

2.83e-05179885bc04789f0fbd293fdcea66acba8cf227af251b7a
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF186 FAM153B FAM153A ANK2 ITPRID2

2.98e-0518188540df0afcb6848202da54670e84f22d7c3a515d01
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF186 FAM153B FAM153A ANK2 ITPRID2

2.98e-051818852b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF186 FAM153B FAM153A ANK2 ITPRID2

2.98e-051818856aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF186 FAM153B FAM153A ANK2 ITPRID2

2.98e-0518188540d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 TOX ARX CHGA CHGB

2.98e-05181885af031661af28f99d906d8e013b4949133b44a2e6
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

DLGAP2 ANK2 CHGA CHGB UNC79

3.06e-0518288557bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ARX CHGA CHGB UNC79

3.06e-051828850e589bf97d51b4b2f723f8c45853ad81b7ce8778
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPS1 ATP2B1 MIER1 NIPBL AKAP12

3.06e-05182885f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 CENPVL3 MAPT CHGA CHGB

3.22e-05184885571136c832cb8c08457744152231537aa8e8abd7
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 DLGAP2 ARX CHGA CHGB

3.22e-051848853da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCell18-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

PRUNE2 DLGAP2 TOX CHGA CHGB

3.31e-05185885f8fc7b12b4e18d23d84e95488be93c4352d325f3
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK2 RIPPLY2 CHGA CHGB UNC79

3.40e-051868852fab7abed16a894afdd0207e86fc43a25a77fb9e
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK2 RIPPLY2 CHGA CHGB UNC79

3.40e-05186885ea2c8e0df038a00062d2098b4a9ac85141b9a728
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK2 RIPPLY2 CHGA CHGB UNC79

3.40e-05186885714765585a644bf9817ab6eb3001b43b3c2d2410
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 PRUNE2 RIPPLY2 SCN2B CHGB

3.48e-051878851b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 PRUNE2 ARX CHGA CHGB

3.48e-0518788598477ba04a42a8da80a72f41a182429f46283595
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 DLGAP2 FLNA FNDC1 AHNAK2

3.57e-0518888574f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CNKSR1 VPS13D EFNB1 AKAP11 ITPRID2

3.57e-051888852c4e791df69a9df29922f9117e5cac7787c129ce
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CNKSR1 VPS13D EFNB1 AKAP11 ITPRID2

3.57e-05188885b1ec7c45aedcc3d22cac898c6a3679e7f8b44c77
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 PRUNE2 MIA3 ANK2 CHGA

3.57e-05188885a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell21-Trachea-Epithelial-Neuroendocrine|Trachea / Age, Tissue, Lineage and Cell class

PRUNE2 ANK2 CHGA CHGB NEB

3.57e-05188885e78d4f7a5d28c77503cb041ff585d13df4c88bd2
ToppCellfacs-Pancreas-Endocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 PRUNE2 ANK2 CHGA CHGB

3.66e-05189885010fdd70e9d0e21b856306a29ff877776a480319
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 PRUNE2 ARX CHGA CHGB

3.76e-051908852375e604eacd38f61f3e661ba2f76d286fcceca7
ToppCellwk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 ANK2 CHGA CHGB UNC79

3.76e-051908855f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 PRUNE2 ARX CHGA CHGB

3.76e-05190885b1095b2a7467c152d16e4f19a9515aeb61fc9e3d
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRH MAPT ARX CHGA CHGB

3.76e-05190885b4dfc41f5a630140cab8b1b86de85de0f5b25e4a
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 MAPT RIPPLY2 CHGA CHGB

3.85e-051918853a5081dc542ac6262acfe5f8084a86616fee8082
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 PRUNE2 RIPPLY2 CHGA CHGB

3.85e-0519188519832ddd559a353e1618fe853d79e3edfec6dcda
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ANK2 MAPT CHGA CHGB

3.95e-05192885d8f5df2c2a50e567f24ebecc8033ac97ba89d9c5
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

CCNF BPTF TROAP MKI67 AHNAK2

3.95e-051928859cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellwk_08-11-Epithelial-PNS-KCNIP4+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ANK2 MAPT RIPPLY2 CHGA CHGB

3.95e-0519288553642c88891f4e4e14b1740c5ced759b7d8b3572
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ANK2 MAPT CHGA CHGB

4.05e-051938859661ea0ee7273928c7de2a9f49e853595fa77699
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

ARFGEF3 BPTF ZFP91 GIGYF2 TASOR2

4.05e-05193885abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 PRUNE2 RIPPLY2 CHGA CHGB

4.05e-051938858603d1a38955ad2529d04e4704467c73ea5bfbda
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ANK2 TRH CHGA CHGB NEB

4.05e-0519388525b1e5a04724023918c8939109a92b35582d5e5c
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP2B1 MIER1 NIPBL FKBP5 AKAP12

4.15e-05194885e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ANK2 MAPT CHGA CHGB

4.15e-0519488515224fb3e7ca5bd1fb8c41f8275842f737014095
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

ARFGEF3 MAPT RIPPLY2 CHGA CHGB

4.15e-05194885b6488bc3a8905e926ad298332963e1bbaf010046
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ANK2 MAPT CHGA CHGB

4.15e-051948855bd0f739aa75f387cca7c3b2686493ee2d1ee968
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

ARFGEF3 MAPT RIPPLY2 CHGA CHGB

4.15e-051948851e1f4139ad584f493d75a9b7f1568eca4653c5a2
ToppCellBLOOD--(1)_T_cell-(1)_Activated_T_cells|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FLNA TOX TROAP MKI67 ATP2B1

4.15e-051948856a0cbb9d5c5c4effb02dff654c6c3b184026875c
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 ANK2 ARX CHGA CHGB

4.15e-05194885b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 PRUNE2 RNF186 CHGA CHGB

4.15e-05194885ccff0b5814f5de2d42720018e7f5dc5dcdafb568
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 PRUNE2 ANK2 CHGA CHGB

4.15e-05194885490645bfe9ed3dac03c191c7094df01c780b377e
ToppCell18-Airway-Epithelial-Epithelial|Airway / Age, Tissue, Lineage and Cell class

PRUNE2 DLGAP2 ANK2 MAPT CHGB

4.15e-05194885d3c90e1f1228f8ba0ba56105c6cf4f302c388f28
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 PRUNE2 RNF186 MIA3 ANK2

4.25e-05195885bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 RIPPLY2 ARX CHGA CHGB

4.25e-051958855f33ece997f074598b4201ff74f592ee07c86a06
ToppCell11.5-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

PRUNE2 RNF186 ARX CHGA CHGB

4.25e-05195885eda6ebe52c48bd6a9044886e75f584f46c2556e7
ToppCellASK452|World / Donor, Lineage and Cell class of Lung cells from Dropseq

PDE4B ATP2B1 JMJD1C FKBP5 AKAP12

4.25e-051958857efd9d3a3f5e7dfe9698a4143ce4a0f9bf3a862c
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ANK2 RIPPLY2 CHGA CHGB NEB

4.46e-05197885ff4df77117165b6b25315e29b0722cc136eba607
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ANK2 MAPT CHGA CHGB

4.46e-05197885b9478212f14b7888e3abac02995177974ac3bd17
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

CCNF EFNB1 USB1 TROAP MKI67

4.46e-051978851bb8f9535a9ab6c7a444bcbe346fcc0a13b09bdf
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ANK2 MAPT CHGA CHGB

4.46e-05197885fd43fc1cbf0c17b370397d73dddc572565a759c7
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CENPVL3 ANK2 MAPT CHGA CHGB

4.46e-05197885a1ae1aa797762a3768e14434c7e5cd19c595ecb3
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDE4B EFNB1 TROAP MKI67 BRME1

4.46e-05197885d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ANK2 MAPT CHGA CHGB

4.46e-051978858951787ed1f7ac1772a6ef0ba2dd44c51fd3c47b
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ANK2 MAPT CHGA CHGB

4.46e-05197885c220102fadbb7ba385a61704a144e0b814cb5c46
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ANK2 MAPT CHGA CHGB

4.57e-051988856483d412b6c0aab58b3348f99231caa5daf65025
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ANK2 MAPT CHGA CHGB

4.57e-05198885b58138581f1a9073267d64c1211c5b9b4de71d3e
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ANK2 MAPT CHGA CHGB

4.57e-05198885dac7b68bb8f1c4d8aa7fdfada61f79956866e874
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KIAA1210 RNF186 FAM153B CHGA CHGB

4.57e-051988852591e08e3fbee86ac40f11becd8147d6d39fded6
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRUNE2 FLNA FNDC1 CHGB FKBP5

4.57e-051988851e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRUNE2 FLNA FNDC1 FAM153B FAM153A

4.57e-0519888522e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

BPTF REST CAMSAP2 NIPBL AHNAK2

4.68e-0519988518a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

ARFGEF3 BPTF ANK2 MAPT ATP2B1

4.68e-051998851b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

ARFGEF3 BPTF ANK2 MAPT ATP2B1

4.68e-051998854bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCelldistal-Endothelial-Capillary-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PDE4B EFNB1 IL18R1 FKBP5 AKAP12

4.79e-05200885ab96d3d801373459a2503ccfb665dc3f43bfb5a1
ToppCell(03)_Secretory-(1)_24hpi|(03)_Secretory / shred by cell type and Timepoint

FLNA BYSL FKBP5 AHNAK2

1.49e-041358846e473296dfe1ff7a63d701e56920c0a1b043ddc6
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNF TRH TROAP MKI67

1.81e-04142884be63c48794a227ea55978524c0f5935342fc455e
ToppCellnormal_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

CENPT TOX CC2D1B S100PBP

2.17e-04149884a34d095b8e0fe59d69d84e4fd2fe4ccb82f92e4f
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

CNKSR1 SPEN JMJD1C TASOR2

2.17e-04149884768877bade04ca0321593b8470b5011ad8270431
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PPIP5K1 IL18R1 KIAA1614 AHNAK2

2.23e-04150884ecc4fc94958cf2378dd003966dccba81b3c00f8e
ToppCellControl-Epithelial-PNEC|Epithelial / Disease state, Lineage and Cell class

TRH RIPPLY2 CHGA CHGB

2.28e-0415188425e7a42989faa01cd41f45b8563725556a5b0cab
Computationalcell line expressed genes.

CCNF FLNA CNKSR1 PDE4B TROAP PPP4R2 SCN2B MKI67 AKAP12

1.13e-04409519MODULE_118
DrugGossypol [303-45-7]; Down 200; 7.8uM; PC3; HT_HG-U133A

CCNF CENPT EFNB1 USB1 OGFR MKI67 PAIP2B USF2

7.14e-071968584296_DN
Drugtyrphostin AG-825; Down 200; 25.2uM; MCF7; HT_HG-U133A_EA

BPTF GIGYF2 ZNF217 SPEN CAMSAP2 NIPBL S100PBP

6.04e-061858571114_DN
DrugGW8510; Down 200; 10uM; MCF7; HT_HG-U133A

CCNF SMG8 TROAP TRPS1 ZNF217 JMJD1C S100PBP

6.48e-061878577080_DN
DrugCalycanthine [595-05-1]; Down 200; 11.6uM; PC3; HT_HG-U133A

VPS13D EFNB1 MAPT OGFR CDADC1 PAIP2B CCDC40

8.52e-061958575744_DN
DrugZuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; HL60; HT_HG-U133A

VPS13D UBE2O PDE4B ANK2 SBF1 NEB LAX1

8.81e-061968572936_DN
DrugNaringin hydrate [11032-30-7]; Down 200; 6.6uM; MCF7; HT_HG-U133A

CNKSR1 VPS13D OGFR REST NEB FKBP5 LAX1

9.11e-061978575666_DN
Drugtestosterone enanthate

PRUNE2 BPTF PDE4B MAPT OGFR CHGA GPATCH8 SPEN CAMSAP2 ATP2B1 FKBP5

9.53e-065758511ctd:C004648
DrugNialamide [51-12-7]; Down 200; 13.4uM; PC3; HT_HG-U133A

VPS13D EFNB1 MAPT OGFR CDADC1 PAIP2B USF2

1.00e-052008574525_DN
DrugGentamicine sulfate [1405-41-0]; Down 200; 2.6uM; PC3; HT_HG-U133A

CCNF VPS13D MAPT OGFR REST NEB USF2

1.00e-052008575883_DN
DrugSn g

TROAP ZFP91 BYSL MIER1

2.19e-0544854CID004369268
Drugirinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A

BPTF TRPS1 GIGYF2 CAMSAP2 ATP2B1 NIPBL

4.40e-051718567535_DN
Diseaseage at diagnosis, osteoarthritis

MAPT RP1L1

1.63e-047832EFO_0004918, MONDO_0005178
Diseaseschizophrenia, gastroesophageal reflux disease

PDE4B GIGYF2

4.23e-0411832EFO_0003948, MONDO_0005090
Diseaseanxiety disorder, stress-related disorder

PDE4B GIGYF2

5.07e-0412832EFO_0006788, EFO_0010098
DiseaseNasal Cavity Polyp

MIA3 GIGYF2 IL18R1

5.07e-0455833EFO_1000391
DiseaseRespiratory Depression

TRH MAPT

5.98e-0413832C0235063
DiseaseRespiratory Insufficiency

TRH MAPT

5.98e-0413832C0035229
DiseaseRespiratory Failure

TRH MAPT

5.98e-0413832C1145670
Diseasenephroblastoma (is_implicated_in)

DIS3L2 REST

6.96e-0414832DOID:2154 (is_implicated_in)
Diseasereticulocyte measurement

FLNA UBE2O ZNF792 MAPT TRPS1 ZNF217 REST SERPINA2 ATP2B1 JMJD1C

7.38e-0410538310EFO_0010700
Diseasefibrinogen measurement, coronary artery disease

MIA3 SERPINA2 ATP2B1 JMJD1C

9.52e-04154834EFO_0001645, EFO_0004623
Diseasesphingosine 1-phosphate measurement

DNAAF3 UBE2O

1.16e-0318832EFO_0800185
Diseaseosteochondrodysplasia (is_implicated_in)

FLNA TRPS1

1.30e-0319832DOID:2256 (is_implicated_in)
Diseaserisk-taking behaviour

DNAAF3 BPTF PDE4B TOX MAPT RP1L1 REST UNC79

1.39e-03764838EFO_0008579
Diseasedocosahexaenoic acid to total fatty acids percentage

MAPT JMJD1C

1.59e-0321832EFO_0022262
DiseaseParkinson disease

MAPT GIGYF2

1.74e-0322832cv:C0030567
Diseaseheart failure

BPTF MIA3 PDE4B MAPT

1.87e-03185834EFO_0003144
Diseasecoronary artery disease

DNAAF3 FNDC1 MIA3 PAIP2B GIGYF2 REST SERPINA2 ATP2B1 FKBP5 AKAP12

1.89e-0311948310EFO_0001645
DiseaseBrugada Syndrome (disorder)

ANK2 SCN2B

2.07e-0324832C1142166
Diseasenevus count, cutaneous melanoma

MIA3 AKAP12 TASOR2

2.18e-0391833EFO_0000389, EFO_0004632
Diseaseperipheral arterial disease, traffic air pollution measurement

DLGAP2 PPP4R2 TRPS1 AKAP12

2.22e-03194834EFO_0004265, EFO_0007908
Diseasemetabolic syndrome

BPTF MIA3 TRPS1 JMJD1C

2.48e-03200834EFO_0000195
DiseaseBone Diseases, Developmental

TRPS1 NIPBL

2.62e-0327832C0005941
Diseasereticulocyte count

UBE2O ZNF792 MAPT TRPS1 ZNF217 REST SERPINA2 ATP2B1 JMJD1C

2.67e-031045839EFO_0007986

Protein segments in the cluster

PeptideGeneStartEntry
KRGGGDEESGEHTQV

AKAP12

536

Q02952
HEDEVEGLGQDGKTL

AKAP11

1796

Q9UKA4
ELEGFPGHITTEDKG

DLGAP2

781

Q9P1A6
GGDPGEEAAEEHKAI

CENPVL1

241

A0A0U1RR11
NEEGKHGPLGDNEER

CDADC1

61

Q9BWV3
GTQGHLGPEKEEEES

DIS3L2

861

Q8IYB7
EQGKSEEPTEVGDKG

BPTF

616

Q12830
EEEGVEKPAETHLSG

DDRGK1

101

Q96HY6
EAGHGTQKEEIPEEE

ATP2B1

1071

P20020
KEDQGLSGHDEKENP

PAIP2B

16

Q9ULR5
SVDVDEPKHTGSGED

ANK2

2631

Q01484
GEGEDHDIPIGIDKA

FKBP5

191

Q13451
KEEEGERQEPGSNHP

PCDHA11

781

Q9Y5I1
EGLEESADIKGEPHG

REST

91

Q13127
FGEENGSDPNIHEEK

IL18R1

251

Q13478
GEEGKPHNNEKAGEE

JMJD1C

411

Q15652
ENEVKEGRGHTPEGT

KIAA1614

686

Q5VZ46
DHAEEGTSEDGTKPD

GPATCH8

321

Q9UKJ3
PVEDGKLGERGHEEG

MAPK6

646

Q16659
EEDSEGPEKEGEGHS

PDE4B

686

Q07343
GDLEDLEEHGPGQTV

FAM153A

111

Q9UHL3
HIELKDNLGSDDPEG

NIPBL

76

Q6KC79
SNIGHVEDKTDDPGT

LAX1

316

Q8IWV1
GETTHTDKEPVGEGK

MKI67

2866

P46013
EVVGPKSEVEEGHGK

ITPRID2

1186

P28290
EEEGDEGGQTHLSPT

SBF1

106

O95248
EDHQGVGLRGEEKPA

RBBP8NL

171

Q8NC74
DEVGDPGTKDLGHPQ

GASK1A

141

Q9UFP1
IDEKGTEATGAPHLE

SERPINA2

366

P20848
GGQKEHLPSIDSEGE

BRME1

231

Q0VDD7
GGDLEEQQHAEGSPE

DNAAF3

331

Q8N9W5
GSVSTEPDDEEGLKH

GIGYF2

476

Q6Y7W6
GGDPGEEAAEEHKAI

CENPVL2

241

P0DPI3
SEGEKEGDVTAPSGI

CCNF

621

P41002
PSGKTHEAEIVEGEN

FLNA

2181

P21333
LSSGIHGDEEDEKPL

FNDC1

871

Q4ZHG4
LEGELGQTTPEDHSG

ARFGEF3

516

Q5TH69
QKGEEAVGSTEHPEE

CCDC40

41

Q4G0X9
GGDPGEEAAEEHKAI

CENPVL3

241

A0A0U1RRI6
GVSGEDEVEPLHDGV

CENPT

316

Q96BT3
DGKHETVNQEEKSGP

EFNB1

206

P98172
ADKDEDEPPGHLQGE

CC2D1B

481

Q5T0F9
LETGTGPLHDEKDES

DDX12P

96

Q92771
LLHPEDAEGKDGEDS

ARX

296

Q96QS3
IPEEGDGSEELAHGH

KIAA1210

786

Q9ULL0
LSDKPHLSGEVGEEA

LINC02913

6

Q8NAJ2
DDGGHVEKGERGSQI

S100PBP

76

Q96BU1
GGSLPSEEKGHPQEE

CHGB

296

P05060
QEELEAEHGTGDKPA

BYSL

66

Q13895
ESKGTLEQRGHNPEE

CAMSAP2

1056

Q08AD1
TNGDLEDLEEHGPGQ

FAM153B

186

P0C7A2
KDLLHSEGSENEGPV

PPP4R2

356

Q9NY27
GDEKGVEAIPEGSHI

MIER1

236

Q8N108
PKAGHSENGVEEDTE

OGFR

491

Q9NZT2
AGHPSLVGEDGQDEV

RNF186

131

Q9NXI6
GGDNPEVHGQVEVKT

SMG8

716

Q8ND04
EGHPETPVDGDLGKQ

PRUNE2

2326

Q8WUY3
HEEKPGEQILEGGSE

MIA3

541

Q5JRA6
GLAGEPEGELSKEDH

MIA3

866

Q5JRA6
DAQHGPQGKEKEDTD

AHNAK2

206

Q8IVF2
EEAQDPEGKGEQEHS

CHGA

286

P10645
VLHEDGPAAEKEGTV

CNKSR1

156

Q969H4
GEEDGHAISTIKEEP

TRPS1

726

Q9UHF7
LKTEEEGKTDGEGNP

SCN2B

196

O60939
DSRSHIKEEGPEGPQ

TEX13D

511

A0A0J9YY54
PGEKEHGQESLSDEL

ZNF691

66

Q5VV52
GEVPSDSDEDGEHKS

SPEN

1376

Q96T58
GSKENGIHEEQDQEP

SNX1

71

Q13596
EEGLPEEGSVHGQEL

RP1L1

1396

Q8IWN7
VDAGGKKEEETPNHA

RIPPLY2

41

Q5TAB7
EDGAPHKEDEPSVGQ

UBE2O

666

Q9C0C9
PKGEREVVTHSDEGG

TROAP

261

Q12815
DEAAGHVTQEPESGK

MAPT

116

P10636
HPSEGNDEKAEEAGE

TMUB2

101

Q71RG4
SHDKGPEAEEGVELQ

USF2

21

Q15853
TEEGPEDDSTKHGGR

USB1

56

Q9BQ65
EEEEGGAVGPHKRQH

TRH

101

P20396
EGKDLPSEHNVSVEG

ZNF792

101

Q3KQV3
EDGLPEGIHLDKNDD

ZNF217

446

O75362
PGEETHGLGGEKALE

TSPYL6

116

Q8N831
NGEPEAELHKETTGP

TASOR2

1696

Q5VWN6
GEEHQSPGGISSEEE

ZFP91

196

Q96JP5
DIEVDGGVGPDTVHK

RPE

171

Q96AT9
VHEDEGDDTSKINGG

TOX

221

O94900
ELHFSPGVKGVEEEG

PPIP5K1

906

Q6PFW1
DSHGSGKNPVIQEEE

ZNF805

186

Q5CZA5
IGPEGEEEENPASKH

UNC79

906

Q9P2D8
EEEENPASKHGENPG

UNC79

911

Q9P2D8
DENLHEKTAEQGGTP

VPS13D

3966

Q5THJ4
ISGGEEKSEHSEAPD

NEB

6546

P20929