Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionguanylate cyclase activity

NPR1 NPR2 GUCY1B1

4.07e-05101423GO:0004383
GeneOntologyMolecularFunctionnatriuretic peptide receptor activity

NPR1 NPR2

1.50e-0431422GO:0016941
GeneOntologyMolecularFunctiontype I interferon receptor binding

IFNA4 IFNA7 IFNA10

2.23e-04171423GO:0005132
GeneOntologyMolecularFunctionadenylate cyclase activity

NPR1 NPR2 GUCY1B1

2.66e-04181423GO:0004016
GeneOntologyMolecularFunctionsmall GTPase binding

UNC13B KNTC1 RGPD2 LZTR1 TSC2 ASB15 ECT2 FMNL3 TBC1D21

4.94e-043211429GO:0031267
GeneOntologyMolecularFunctionHsp90 protein binding

FKBP6 ERN1 TSC2 GUCY1B1

6.31e-04551424GO:0051879
GeneOntologyMolecularFunctioncyclase activity

NPR1 NPR2 GUCY1B1

6.39e-04241423GO:0009975
GeneOntologyMolecularFunctionphosphorus-oxygen lyase activity

NPR1 NPR2 GUCY1B1

7.22e-04251423GO:0016849
GeneOntologyBiologicalProcesscellular response to type I interferon

SIN3A IFIT1 IFNA4 IFNA7 IFNA10 IFIH1

2.54e-05861396GO:0071357
GeneOntologyBiologicalProcessmotile cilium assembly

SPEF2 CFAP43 CCDC39 DYNLL1 TBC1D21 HTT

2.89e-05881396GO:0044458
GeneOntologyBiologicalProcessresponse to exogenous dsRNA

IFIT1 IFNA4 IFNA7 IFNA10 IFIH1

3.43e-05551395GO:0043330
GeneOntologyBiologicalProcessresponse to type I interferon

SIN3A IFIT1 IFNA4 IFNA7 IFNA10 IFIH1

3.73e-05921396GO:0034340
GeneOntologyBiologicalProcessprotein localization to organelle

KNTC1 RGPD2 GDAP1 OBSCN TOPBP1 PTPN23 NBEA TSC2 SIN3A CUBN MTERF4 ECT2 CCDC39 GHSR TBC1D32 VPS13D INTS13 VPS13A NUP188 HTT

4.35e-05109113920GO:0033365
GeneOntologyBiologicalProcesscGMP biosynthetic process

NPR1 NPR2 GUCY1B1

6.30e-05121393GO:0006182
GeneOntologyBiologicalProcessresponse to dsRNA

IFIT1 IFNA4 IFNA7 IFNA10 IFIH1

6.64e-05631395GO:0043331
GeneOntologyBiologicalProcesscilium organization

SPEF2 RTTN PTPN23 CFAP43 CCDC39 TBC1D32 TRIM32 DYNLL1 TBC1D21 BBS12 HTT CFAP46

9.37e-0547613912GO:0044782
GeneOntologyBiologicalProcessaxoneme assembly

SPEF2 CFAP43 CCDC39 TBC1D32 TBC1D21 CFAP46

9.63e-051091396GO:0035082
GeneOntologyBiologicalProcessdefense response to virus

RELA SIN3A ITGAX IFIT1 IFNA4 IFNA7 IFNA10 IFIH1 TRIM32 IFIT1B

1.11e-0434213910GO:0051607
GeneOntologyBiologicalProcessresponse to virus

RELA SIN3A ITGAX WDFY4 IFIT1 IFNA4 IFNA7 IFNA10 IFIH1 TRIM32 IFIT1B

1.47e-0442513911GO:0009615
GeneOntologyCellularComponentstriated muscle myosin thick filament

OBSCN TRIM32

2.88e-0441462GO:0005863
GeneOntologyCellularComponentcytoplasmic vesicle membrane

UNC13B APPBP2 LZTR1 COPA COPB1 GRIN1 CUBN ASB15 ITGAX SNX19 SEMA4C MCTP1 PTPRJ EGFR VPS13A AP1G2 DYNLL1 ATP6V0D2 DMD HTT DOP1B

2.98e-04130714621GO:0030659
GeneOntologyCellularComponentvesicle membrane

UNC13B APPBP2 LZTR1 COPA COPB1 GRIN1 CUBN ASB15 ITGAX SNX19 SEMA4C MCTP1 PTPRJ EGFR VPS13A AP1G2 DYNLL1 ATP6V0D2 DMD HTT DOP1B

3.58e-04132514621GO:0012506
DomainARM-type_fold

COPB1 DOCK8 RTTN ARFGEF1 NBEA TSC2 WDFY4 VIRMA NCAPG2 FMNL3 ANKAR IFRD2 LTN1 INTS4 AP1G2 ZER1 NUP188 ARMH3 HTT

1.76e-1133914519IPR016024
DomainARM-like

COPB1 DOCK8 RTTN ARFGEF1 NBEA TSC2 WDFY4 NCAPG2 ANKAR IFRD2 LTN1 INTS4 AP1G2 ZER1 HTT

3.03e-0927014515IPR011989
Domain-

COPB1 RTTN ARFGEF1 TSC2 WDFY4 NCAPG2 ANKAR IFRD2 INTS4 AP1G2 ZER1 HTT

1.66e-07222145121.25.10.10
DomainTPR_REGION

RGPD2 APPBP2 FKBP6 PTPN23 IFIT1 IFIT1B VPS13A CFAP46

4.47e-051651458PS50293
DomainTPR

RGPD2 APPBP2 FKBP6 PTPN23 IFIT1 IFIT1B VPS13A CFAP46

4.47e-051651458PS50005
DomainHDAC_interact

SIN3B SIN3A

5.99e-0521452SM00761
DomainSin3_C

SIN3B SIN3A

5.99e-0521452IPR031693
DomainSin3_corepress

SIN3B SIN3A

5.99e-0521452PF08295
DomainSin3a_C

SIN3B SIN3A

5.99e-0521452PF16879
DomainHDAC_interact_dom

SIN3B SIN3A

5.99e-0521452IPR013194
DomainTPR-contain_dom

RGPD2 APPBP2 FKBP6 PTPN23 IFIT1 IFIT1B VPS13A

1.72e-041501457IPR013026
DomainPAH

SIN3B SIN3A

1.79e-0431452IPR003822
Domain-

SIN3B SIN3A

1.79e-04314521.20.1160.11
DomainPAH

SIN3B SIN3A

1.79e-0431452PS51477
DomainVPS13

VPS13D VPS13A

1.79e-0431452IPR026847
DomainANF_RECEPTORS

NPR1 NPR2

1.79e-0431452PS00458
DomainVPS13_mid_rpt

VPS13D VPS13A

1.79e-0431452PF16910
DomainVPS13

VPS13D VPS13A

1.79e-0431452PF16908
DomainVPS13_N2

VPS13D VPS13A

1.79e-0431452IPR031646
DomainVPS13_mid_rpt

VPS13D VPS13A

1.79e-0431452IPR031642
DomainPAH

SIN3B SIN3A

1.79e-0431452PF02671
DomainANPR/GUC

NPR1 NPR2

1.79e-0431452IPR001170
DomainA/G_cyclase_CS

NPR1 NPR2 GUCY1B1

2.88e-04171453IPR018297
DomainInterferon

IFNA4 IFNA7 IFNA10

2.88e-04171453PF00143
DomainINTERFERON_A_B_D

IFNA4 IFNA7 IFNA10

2.88e-04171453PS00252
DomainInterferon_alpha/beta/delta

IFNA4 IFNA7 IFNA10

2.88e-04171453IPR000471
DomainIFabd

IFNA4 IFNA7 IFNA10

2.88e-04171453SM00076
Domain-

NPR1 NPR2 GUCY1B1

3.43e-041814533.30.70.1230
DomainNucleotide_cyclase

NPR1 NPR2 GUCY1B1

3.43e-04181453IPR029787
DomainTEA_1

TEAD2 TEAD4

3.56e-0441452PS00554
DomainTEA_2

TEAD2 TEAD4

3.56e-0441452PS51088
DomainSHR-BD

VPS13D VPS13A

3.56e-0441452IPR009543
DomainTEA

TEAD2 TEAD4

3.56e-0441452PF01285
DomainTEA/ATTS_dom

TEAD2 TEAD4

3.56e-0441452IPR000818
DomainTEF_metazoa

TEAD2 TEAD4

3.56e-0441452IPR016361
DomainPTCB-BRCT

TOPBP1 ECT2

3.56e-0441452PF12738
DomainTEA

TEAD2 TEAD4

3.56e-0441452SM00426
DomainVPS13_C

VPS13D VPS13A

3.56e-0441452PF16909
DomainVPS13_C

VPS13D VPS13A

3.56e-0441452IPR031645
DomainSHR-BD

VPS13D VPS13A

3.56e-0441452PF06650
DomainGuanylate_cyc

NPR1 NPR2 GUCY1B1

4.05e-04191453PF00211
DomainGUANYLATE_CYCLASE_2

NPR1 NPR2 GUCY1B1

4.05e-04191453PS50125
DomainA/G_cyclase

NPR1 NPR2 GUCY1B1

4.05e-04191453IPR001054
DomainGUANYLATE_CYCLASE_1

NPR1 NPR2 GUCY1B1

4.05e-04191453PS00452
DomainCYCc

NPR1 NPR2 GUCY1B1

4.05e-04191453SM00044
DomainTF_AP2

TFAP2A TFAP2B

5.89e-0451452IPR004979
DomainTF_AP2_C

TFAP2A TFAP2B

5.89e-0451452IPR013854
DomainBRO1

PTPN23 BROX

5.89e-0451452PF03097
DomainBRO1_dom

PTPN23 BROX

5.89e-0451452IPR004328
DomainBRO1

PTPN23 BROX

5.89e-0451452SM01041
DomainTF_AP-2

TFAP2A TFAP2B

5.89e-0451452PF03299
DomainBRO1

PTPN23 BROX

5.89e-0451452PS51180
Domain-

PTPN23 BROX

5.89e-04514521.25.40.280
DomainGrowth_fac_rcpt_

FRAS1 BRINP3 CUBN THBS4 HMCN1 EGFR

1.38e-031561456IPR009030
DomainDH_1

ARHGEF28 OBSCN ECT2 ARHGEF37

1.46e-03631454PS00741
DomainChorein_N

VPS13D VPS13A

1.63e-0381452PF12624
DomainHelicase/UvrB_N

FANCM IFIH1

1.63e-0381452IPR006935
DomainPH-BEACH_dom

NBEA WDFY4

1.63e-0381452IPR023362
DomainCalx_beta

FRAS1 FREM3

1.63e-0381452SM00237
DomainVPS13_N

VPS13D VPS13A

1.63e-0381452IPR026854
Domain-

NBEA WDFY4

1.63e-03814522.30.29.40
DomainPH_BEACH

NBEA WDFY4

1.63e-0381452PS51783
DomainResIII

FANCM IFIH1

1.63e-0381452PF04851
DomainRhoGEF

ARHGEF28 OBSCN ECT2 ARHGEF37

1.93e-03681454SM00325
DomainCalx_beta

FRAS1 FREM3

2.08e-0391452IPR003644
DomainBEACH

NBEA WDFY4

2.08e-0391452PS50197
DomainBeach

NBEA WDFY4

2.08e-0391452PF02138
Domain-

NBEA WDFY4

2.08e-03914521.10.1540.10
DomainBeach

NBEA WDFY4

2.08e-0391452SM01026
DomainBEACH_dom

NBEA WDFY4

2.08e-0391452IPR000409
DomainCalx-beta

FRAS1 FREM3

2.08e-0391452PF03160
DomainRhoGEF

ARHGEF28 OBSCN ECT2 ARHGEF37

2.15e-03701454PF00621
DomainDH_2

ARHGEF28 OBSCN ECT2 ARHGEF37

2.15e-03701454PS50010
Domain-

ARHGEF28 OBSCN ECT2 ARHGEF37

2.26e-037114541.20.900.10
DomainDH-domain

ARHGEF28 OBSCN ECT2 ARHGEF37

2.26e-03711454IPR000219
DomainPTPc

PTPN23 PTPRJ PTPRR

2.71e-03361453SM00194
DomainANF_lig-bd_rcpt

NPR1 NPR2 GRIN1

2.94e-03371453IPR001828
DomainANF_receptor

NPR1 NPR2 GRIN1

2.94e-03371453PF01094
DomainTPR

RGPD2 APPBP2 FKBP6 IFIT1 IFIT1B

3.35e-031291455SM00028
DomainPeripla_BP_I

NPR1 NPR2 GRIN1

3.41e-03391453IPR028082
DomainTYR_PHOSPHATASE_PTP

PTPN23 PTPRJ PTPRR

3.41e-03391453PS50055
DomainTPR_repeat

RGPD2 APPBP2 FKBP6 IFIT1 IFIT1B

3.82e-031331455IPR019734
DomainPTPase_domain

PTPN23 PTPRJ PTPRR

3.94e-03411453IPR000242
DomainY_phosphatase

PTPN23 PTPRJ PTPRR

3.94e-03411453PF00102
Domain-

COPA NBEA CFAP43 EDC4 WDFY4 SEMA4C NBAS NWD2

4.53e-0333314582.130.10.10
DomainIg_V-set

BTNL8 OBSCN CEACAM4 JAM2 HMCN1 TREM1

4.64e-031991456IPR013106
DomainWD40/YVTN_repeat-like_dom

COPA NBEA CFAP43 EDC4 WDFY4 SEMA4C NBAS NWD2

4.70e-033351458IPR015943
Domain-

RGPD2 APPBP2 FKBP6 IFIT1 IFIT1B CFAP46

5.61e-0320714561.25.40.10
DomainClathrin/coatomer_adapt-like_N

COPB1 AP1G2

5.88e-03151452IPR002553
DomainAdaptin_N

COPB1 AP1G2

5.88e-03151452PF01602
DomainWD_REPEATS_1

COPA NBEA CFAP43 EDC4 WDFY4 NBAS NWD2

6.07e-032781457PS00678
DomainHEAT

NCAPG2 INTS4 HTT

6.14e-03481453PF02985
DomainWD_REPEATS_2

COPA NBEA CFAP43 EDC4 WDFY4 NBAS NWD2

6.19e-032791457PS50082
DomainWD_REPEATS_REGION

COPA NBEA CFAP43 EDC4 WDFY4 NBAS NWD2

6.19e-032791457PS50294
Domain-

IFNA4 IFNA7 IFNA10

6.88e-035014531.20.1250.10
Domain4_helix_cytokine_core

IFNA4 IFNA7 IFNA10

7.27e-03511453IPR012351
PathwayKEGG_MEDICUS_PATHOGEN_HIV_TAT_TO_TLR2_4_NFKB_SIGNALING_PATHWAY

RELA IFNA4 IFNA7 IFNA10

6.42e-06171054M47564
PathwayKEGG_MEDICUS_REFERENCE_RIG_I_NFKB_SIGNALING_PATHWAY

RELA IFNA4 IFNA7 IFNA10

1.92e-05221054M47616
PathwayKEGG_MEDICUS_REFERENCE_MDA5_IRF7_3_SIGNALING_PATHWAY

IFNA4 IFNA7 IFNA10 IFIH1

2.75e-05241054M47782
PathwayREACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION

IFNA4 IFNA7 IFNA10 IFIH1

6.86e-05301054M936
PathwayWP_SARS_CORONAVIRUS_AND_INNATE_IMMUNITY

IFNA4 IFNA7 IFNA10 IFIH1

7.83e-05311054M39897
PathwayREACTOME_EVASION_BY_RSV_OF_HOST_INTERFERON_RESPONSES

IFNA4 IFNA7 IFNA10 IFIH1

1.27e-04351054M48246
PathwayREACTOME_TFAP2_AP_2_FAMILY_REGULATES_TRANSCRIPTION_OF_GROWTH_FACTORS_AND_THEIR_RECEPTORS

TFAP2A TFAP2B EGFR

1.71e-04151053M27766
PathwayKEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY

RELA IFNA4 IFNA7 IFNA10 IFIH1

1.84e-04711055M15913
PathwayBIOCARTA_IL1R_PATHWAY

RELA IFNA4 IFNA7 IFNA10

2.38e-04411054MM1493
PathwayWP_TRANSCRIPTION_COFACTORS_SKI_AND_SKIL_PROTEIN_PARTNERS

TEAD2 SIN3A TEAD4

3.02e-04181053M39825
PathwayKEGG_MEDICUS_REFERENCE_CGAS_STING_SIGNALING_PATHWAY

IFNA4 IFNA7 IFNA10

3.02e-04181053M47539
PathwayBIOCARTA_IFNA_PATHWAY

IFNA4 IFNA7 IFNA10

3.57e-04191053MM1571
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF7_SIGNALING_PATHWAY

IFNA4 IFNA7 IFNA10

3.57e-04191053M47450
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM

GRIN1 HTT VDAC2

3.57e-04191053M47677
PathwayREACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA

RELA IFNA4 IFNA7 IFNA10 IFIH1

3.61e-04821055M1002
PathwayWP_NOCGMPPKG_MEDIATED_NEUROPROTECTION

NPR1 RELA GRIN1 GUCY1B1

4.05e-04471054M39531
PathwayKEGG_MEDICUS_REFERENCE_TLR7_9_IRF7_SIGNALING_PATHWAY

IFNA4 IFNA7 IFNA10

4.17e-04201053M47617
PathwayKEGG_MEDICUS_REFERENCE_TYPE_II_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY

IFNA4 IFNA7 IFNA10

4.84e-04211053M47909
PathwayKEGG_MEDICUS_REFERENCE_TLR7_8_9_IRF5_SIGNALING_PATHWAY

IFNA4 IFNA7 IFNA10

5.58e-04221053M47897
PathwayKEGG_MEDICUS_REFERENCE_TYPE_I_IFN_SIGNALING_PATHWAY

IFNA4 IFNA7 IFNA10

6.38e-04231053M47452
PathwayREACTOME_REGULATION_OF_IFNA_IFNB_SIGNALING

IFNA4 IFNA7 IFNA10

6.38e-04231053MM15634
PathwayKEGG_MEDICUS_REFERENCE_RIG_I_IRF7_3_SIGNALING_PATHWAY

IFNA4 IFNA7 IFNA10

7.25e-04241053M47576
PathwayKEGG_MEDICUS_REFERENCE_TYPE_I_INTERFERON_TO_JAK_STAT_SIGNALING_PATHWAY

IFNA4 IFNA7 IFNA10

7.25e-04241053M47908
PathwayKEGG_CYTOSOLIC_DNA_SENSING_PATHWAY

RELA IFNA4 IFNA7 IFNA10

7.40e-04551054M11844
PathwayREACTOME_RUNX3_REGULATES_YAP1_MEDIATED_TRANSCRIPTION

TEAD2 TEAD4

8.08e-0461052MM15544
Pubmed

Aicardi-Goutières syndrome-like encephalitis in mutant mice with constitutively active MDA5.

IFIT1 IFNA4 IFNA7 IFNA10 IFIH1 IFIT1B

1.47e-0927148633165593
Pubmed

PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon Response.

IFIT1 IFNA4 IFNA7 IFNA10 IFIT1B

5.19e-0824148535037428
Pubmed

LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner.

IFIT1 IFNA4 IFNA7 IFNA10 IFIT1B

6.47e-0825148527183626
Pubmed

The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation.

IFIT1 IFNA4 IFNA7 IFNA10 IFIT1B

7.98e-0826148538744293
Pubmed

The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.

IFIT1 IFNA4 IFNA7 IFNA10 IFIT1B

9.76e-0827148525456137
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CA12 SIN3B APPBP2 OBSCN NBEA TSC2 GRIN1 ECT2 CCDC39 RYR1 IGF2BP3 THBS4 EXOC3L4 VPS13A NUP188 DOP1B

1.13e-077361481629676528
Pubmed

Murine coronavirus induces type I interferon in oligodendrocytes through recognition by RIG-I and MDA5.

IFNA4 IFNA7 IFNA10 IFIH1

2.18e-0713148420427526
Pubmed

Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity.

IFIT1 IFIH1 IFIT1B

3.01e-074148324478444
Pubmed

Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response.

IFNA4 IFNA7 IFNA10 IFIH1

3.05e-0714148420566717
Pubmed

Development of IFN-Stimulated Gene Expression from Embryogenesis through Adulthood, with and without Constitutive MDA5 Pathway Activation.

IFIT1 IFIH1 IFIT1B

1.50e-066148332277054
Pubmed

RNA editing at a limited number of sites is sufficient to prevent MDA5 activation in the mouse brain.

IFIT1 IFIH1 IFIT1B

2.61e-067148333983932
Pubmed

Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor.

TEAD2 RELA TEAD4

2.61e-067148316207754
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

UNC13B TEAD2 FRAS1 LZTR1 RTTN OBSCN TSC2 CFAP43 EDC4 RYR1 SBNO2 IFRD2 AP1G2 ZER1 ZFYVE26 NUP188 HTT

5.17e-0611051481735748872
Pubmed

ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development.

IFIT1 TFAP2A TFAP2B IFIH1 IFIT1B

5.42e-0659148531924792
Pubmed

Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN.

ITGAX IFNA4 IFNA7 IFNA10

5.95e-0628148417277142
Pubmed

An essential role for Cmtr2 in mammalian embryonic development.

IFIT1 IFIH1 IFIT1B

6.23e-069148339094818
Pubmed

Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity.

IFIT1 IFIH1 IFIT1B

8.87e-0610148326633895
Pubmed

High-affinity binding of 125I-labelled mouse interferon to a specific cell surface receptor.

IFNA4 IFNA7 IFNA10

1.22e-051114836444699
Pubmed

Mechanism of SUMOylation-Mediated Regulation of Type I IFN Expression.

IFNA4 IFNA7 IFNA10

1.22e-0511148336681180
Pubmed

Type I interferon dependence of plasmacytoid dendritic cell activation and migration.

IFNA4 IFNA7 IFNA10

1.22e-0511148315795237
Pubmed

Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration.

IFNA4 IFNA7 IFNA10

1.22e-051114839794439
Pubmed

Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis.

IFNA4 IFNA7 IFNA10

1.22e-0511148318835032
Pubmed

Structural and functional neuropathology in transgenic mice with CNS expression of IFN-alpha.

IFNA4 IFNA7 IFNA10

1.22e-0511148310448195
Pubmed

IFN-alpha can both protect against and promote the development of type 1 diabetes.

IFNA4 IFNA7 IFNA10

1.22e-0511148319120292
Pubmed

Effect of interferon-alpha on immediate early gene expression of murine cytomegalovirus.

IFNA4 IFNA7 IFNA10

1.22e-051114838389790
Pubmed

The mouse IFN-alpha (Ifa) locus: correlation of physical and linkage maps by in situ hybridization.

IFNA4 IFNA7 IFNA10

1.22e-051114833456887
Pubmed

Recombinant rabies virus expressing IFNα1 enhanced immune responses resulting in its attenuation and stronger immunogenicity.

IFNA4 IFNA7 IFNA10

1.22e-0511148325310498
Pubmed

MAVS Deficiency Is Associated With a Reduced T Cell Response Upon Secondary RSV Infection in Mice.

IFNA4 IFNA7 IFNA10

1.62e-0512148333123150
Pubmed

A novel anti-viral role for STAT3 in IFN-α signalling responses.

IFNA4 IFNA7 IFNA10

1.62e-0512148327988795
Pubmed

IFN-alpha-mediated suppression of low-affinity FC(epsilon) receptors on Peyer's patch lymphocytes and augmentation of soluble CD23: implications for IgE responses.

IFNA4 IFNA7 IFNA10

1.62e-051214838656058
Pubmed

Structure and expression of cloned murine IFN-alpha genes.

IFNA4 IFNA7 IFNA10

1.62e-051214836188104
Pubmed

Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice.

IFNA4 IFNA7 IFNA10

1.62e-0512148318716002
Pubmed

Negative regulation of the alpha interferon-induced antiviral response by the Ras/Raf/MEK pathway.

IFNA4 IFNA7 IFNA10

1.62e-0512148316611902
Pubmed

Obesity worsens the outcome of influenza virus infection associated with impaired type I interferon induction in mice.

IFNA4 IFNA7 IFNA10

1.62e-0512148330967261
Pubmed

Antiviral and myocyte protective effects of murine interferon-beta and -{alpha}2 in coxsackievirus B3-induced myocarditis and epicarditis in Balb/c mice.

IFNA4 IFNA7 IFNA10

1.62e-0512148317434974
Pubmed

Mapping the genetic region coding for herpes simplex virus resistance to mouse interferon alpha/beta.

IFNA4 IFNA7 IFNA10

1.62e-051214838245849
Pubmed

Sequence and expression of a novel murine interferon alpha gene--homology with enhancer elements in the regulatory region of the gene.

IFNA4 IFNA7 IFNA10

1.62e-051214833017340
Pubmed

Role of interferons in the regulation of cell proliferation, differentiation, and development.

IFNA4 IFNA7 IFNA10

1.62e-051214837530016
Pubmed

Nonviral interferon alpha gene therapy inhibits growth of established tumors by eliciting a systemic immune response.

IFNA4 IFNA7 IFNA10

1.62e-051214839794206
Pubmed

Isolation and mapping of four new DNA markers from mouse chromosome 4.

IFNA4 IFNA7 IFNA10

1.62e-051214831360280
Pubmed

Interferon-alpha/beta can impede development of carcinogen-induced squamous-cell tumors in the esophagus of C57B1 mice.

IFNA4 IFNA7 IFNA10

1.62e-051214837601556
Pubmed

Type I interferon production by tertiary lymphoid tissue developing in response to 2,6,10,14-tetramethyl-pentadecane (pristane).

IFNA4 IFNA7 IFNA10

1.62e-0512148316565497
Pubmed

Regulation of effector and memory T-cell functions by type I interferon.

IFNA4 IFNA7 IFNA10

1.62e-0512148321320124
Pubmed

Evolution of the interferon alpha gene family in eutherian mammals.

IFNA4 IFNA7 IFNA10

1.62e-0512148317512142
Pubmed

Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes.

IFNA4 IFNA7 IFNA10

1.62e-051214839425112
Pubmed

Repression of the murine interferon alpha 11 gene: identification of negatively acting sequences.

IFNA4 IFNA7 IFNA10

1.62e-051214831886773
Pubmed

The physical separation of Lps and Ifa loci in BXH recombinant inbred mice.

IFNA4 IFNA7 IFNA10

1.62e-051214832572648
Pubmed

Developmental control of IFN-alpha expression in murine embryos.

IFNA4 IFNA7 IFNA10

1.62e-051214837925651
Pubmed

The role of type 1 interferons in coagulation induced by gram-negative bacteria.

IFNA4 IFNA7 IFNA10

1.62e-0512148332016282
Pubmed

Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis.

IFIT1 IFIH1 IFIT1B

1.62e-0512148328874170
Pubmed

Multiple pathways of interferon-induced gene expression in murine macrophages.

IFNA4 IFNA7 IFNA10

1.62e-051214837684767
Pubmed

Ligation of CD180 inhibits IFN-α signaling in a Lyn-PI3K-BTK-dependent manner in B cells.

IFNA4 IFNA7 IFNA10

1.62e-0512148326277892
Pubmed

Mapping of murine interferon-alpha genes to chromosome 4.

IFNA4 IFNA7 IFNA10

1.62e-051214836689487
Pubmed

Interferon-alpha subtype 11 activates NK cells and enables control of retroviral infection.

IFNA4 IFNA7 IFNA10

1.62e-0512148322912583
Pubmed

The antiviral cytokines IFN-α and IFN-β modulate parietal epithelial cells and promote podocyte loss: implications for IFN toxicity, viral glomerulonephritis, and glomerular regeneration.

IFNA4 IFNA7 IFNA10

1.62e-0512148323747509
Pubmed

Mutation of the IFNAR-1 receptor binding site of human IFN-alpha2 generates type I IFN competitive antagonists.

IFNA4 IFNA7 IFNA10

1.62e-0512148318937499
Pubmed

Structure and expression of a new murine interferon-alpha gene: MuIFN-alpha I9.

IFNA4 IFNA7 IFNA10

1.62e-051214833758677
Pubmed

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling.

IFNA4 IFNA7 IFNA10

1.62e-0512148319406830
Pubmed

AAV2-mediated combined subretinal delivery of IFN-α and IL-4 reduces the severity of experimental autoimmune uveoretinitis.

IFNA4 IFNA7 IFNA10

1.62e-0512148322685550
Pubmed

Interferon-alpha/beta genes are up-regulated in murine brain astrocytes after infection with Theiler's murine encephalomyelitis virus.

IFNA4 IFNA7 IFNA10

1.62e-0512148320038206
Pubmed

Murine alpha/beta interferons inhibit benzo(a)pyrene activation and mutagenesis in mice.

IFNA4 IFNA7 IFNA10

1.62e-051214838304945
Pubmed

The virus-induced factor VIF differentially recognizes the virus-responsive modules of the mouse IFNA4 gene promoter.

IFNA4 IFNA7 IFNA10

1.62e-0512148311846978
Pubmed

Identification of distal silencing elements in the murine interferon-A11 gene promoter.

IFNA4 IFNA7 IFNA10

1.62e-051214838760352
Pubmed

Behavioral effects of mouse interferons-alpha and -gamma and human interferon-alpha in mice.

IFNA4 IFNA7 IFNA10

1.62e-051214831422836
Pubmed

Suppression of the effector phase of inflammatory arthritis by double-stranded RNA is mediated by type I IFNs.

IFNA4 IFNA7 IFNA10

1.62e-0512148317277125
Pubmed

Characterization of murine interferon-alpha 12 (MuIFN-alpha12): biological activities and gene expression.

IFNA4 IFNA7 IFNA10

1.62e-0512148317451966
Pubmed

Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes.

IFNA4 IFNA7 IFNA10

1.62e-0512148325897172
Pubmed

A polymorphic trinucleotide repeat sequence mapping to distal mouse chromosome 4.

IFNA4 IFNA7 IFNA10

1.62e-051214838672140
Pubmed

AP-2α/AP-2β Transcription Factors Are Key Regulators of Epidermal Homeostasis.

TFAP2A TFAP2B

1.80e-052148238237728
Pubmed

Exome sequencing identifies novel compound heterozygous IFNA4 and IFNA10 mutations as a cause of impaired function in Crohn's disease patients.

IFNA4 IFNA10

1.80e-052148226000985
Pubmed

RING finger protein AO7 supports NF-kappaB-mediated transcription by interacting with the transactivation domain of the p65 subunit.

RNF25 RELA

1.80e-052148212748188
Pubmed

Ifit1 inhibits Japanese encephalitis virus replication through binding to 5' capped 2'-O unmethylated RNA.

IFIT1 IFIT1B

1.80e-052148223824812
Pubmed

Mutant huntingtin regulates EGF receptor fate in non-neuronal cells lacking wild-type protein.

EGFR HTT

1.80e-052148222974559
Pubmed

A viral RNA structural element alters host recognition of nonself RNA.

IFIT1 IFIT1B

1.80e-052148224482115
Pubmed

Vasonatrin peptide stimulates both of the natriuretic peptide receptors, NPRA and NPRB.

NPR1 NPR2

1.80e-052148224699414
Pubmed

IGF2BP3 promotes the progression of colorectal cancer and mediates cetuximab resistance by stabilizing EGFR mRNA in an m6A-dependent manner.

IGF2BP3 EGFR

1.80e-052148237658049
Pubmed

Metabolic Reprogramming Driven by IGF2BP3 Promotes Acquired Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer.

IGF2BP3 EGFR

1.80e-052148237061993
Pubmed

IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I Interferon.

IFIT1 IFIT1B

1.80e-052148225927359
Pubmed

IFIT1 Exerts Opposing Regulatory Effects on the Inflammatory and Interferon Gene Programs in LPS-Activated Human Macrophages.

IFIT1 IFIT1B

1.80e-052148230282041
Pubmed

TFAP2A is involved in neuropathic pain by regulating Grin1 expression in glial cells of the dorsal root ganglion.

GRIN1 TFAP2A

1.80e-052148239009095
Pubmed

Anti-EGFR antibody efficiently and specifically inhibits human TSC2-/- smooth muscle cell proliferation. Possible treatment options for TSC and LAM.

TSC2 EGFR

1.80e-052148218958173
Pubmed

Guanylyl cyclases A and B are asymmetric dimers that are allosterically activated by ATP binding to the catalytic domain.

NPR1 NPR2

1.80e-052148222949736
Pubmed

Enhanced expression of natriuretic peptide receptor A and B in neutrophils of culprit lesions in patients with acute myocardial infarction.

NPR1 NPR2

1.80e-052148228765884
Pubmed

Predictive value of maternal serum NF-κB p65 and sTREM-1 for subclinical chorioamnionitis in premature rupture of membranes.

RELA TREM1

1.80e-052148227521929
Pubmed

Ifit1 Protects Against Lipopolysaccharide and D-galactosamine-Induced Fatal Hepatitis by Inhibiting Activation of the JNK Pathway.

IFIT1 IFIT1B

1.80e-052148226459629
Pubmed

Mouse Ifit1b is a cap1-RNA-binding protein that inhibits mouse coronavirus translation and is regulated by complexing with Ifit1c.

IFIT1 IFIT1B

1.80e-052148233454014
Pubmed

Adenine nucleotides decrease the apparent Km of endogenous natriuretic peptide receptors for GTP.

NPR1 NPR2

1.80e-052148217848634
Pubmed

Mass spectrometric identification of phosphorylation sites in guanylyl cyclase A and B.

NPR1 NPR2

1.80e-052148220977274
Pubmed

Identification and validation of Ifit1 as an important innate immune bottleneck.

IFIT1 IFIT1B

1.80e-052148222745654
Pubmed

AP2 transcription factor induces apoptosis in retinoblastoma cells.

TFAP2A TFAP2B

1.80e-052148220607706
Pubmed

Differential Complex Formation via Paralogs in the Human Sin3 Protein Interaction Network.

SIN3B SIN3A

1.80e-052148232467258
Pubmed

IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux.

ERN1 HTT

1.80e-052148221954231
Pubmed

The indolocarbazole, Gö6976, inhibits guanylyl cyclase-A and -B.

NPR1 NPR2

1.80e-052148221366551
Pubmed

Conditional Deletion of AP-2α and AP-2β in the Developing Murine Retina Leads to Altered Amacrine Cell Mosaics and Disrupted Visual Function.

TFAP2A TFAP2B

1.80e-052148229715367
Pubmed

IGF2 mRNA binding protein 3 (IMP3) promotes glioma cell migration by enhancing the translation of RELA/p65.

RELA IGF2BP3

1.80e-052148228465487
Pubmed

The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate.

NPR1 NPR2

1.80e-052148230696704
Pubmed

Chimeric natriuretic peptide ACNP stimulates both natriuretic peptide receptors, the NPRA and NPRB.

NPR1 NPR2

1.80e-052148223186809
Pubmed

WDFY4 polymorphisms in Chinese patients with anti-MDA5 dermatomyositis is associated with rapid progressive interstitial lung disease.

WDFY4 IFIH1

1.80e-052148236637178
Pubmed

Overexpression of IFIT1 protects against LPS-induced acute lung injury via regulating CCL5-p65NF-κB signaling.

IFIT1 IFIT1B

1.80e-052148236446235
Pubmed

The association between expression of IFIT1 in podocytes of MRL/lpr mice and the renal pathological changes it causes: An animal study.

IFIT1 IFIT1B

1.80e-052148227823966
Cytoband9p22

IFNA4 IFNA7 IFNA10

7.17e-052514839p22
GeneFamilyTEA domain transcription factors

TEAD2 TEAD4

1.80e-04410021183
GeneFamilyGuanylate cyclase receptors

NPR1 NPR2

6.25e-0471002343
GeneFamilyInterferons

IFNA4 IFNA7 IFNA10

7.25e-04321003598
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEA WDFY4

1.06e-03910021230
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

SIN3B SIN3A

1.06e-03910021306
GeneFamilyX-linked mental retardation|RNA helicases

FANCM IFIH1

1.61e-031110021168
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

SIN3B SIN3A

1.93e-031210021243
GeneFamilyIntegrator complex

INTS13 INTS4

3.03e-031510021366
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD2 IFIT1 IFIT1B CFAP46

3.81e-031151004769
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

OBSCN ECT2 ARHGEF37

5.84e-03661003722
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRJ PTPRR

5.94e-03211002813
GeneFamilyBardet-Biedl syndrome associated|BBSome

TRIM32 BBS12

5.94e-03211002980
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_OMD_POS_ENDOTHELIAL_CELL

CPAMD8 SFRP4 PI16 CUBN IFIH1 MCTP1 HMCN1 PTPRJ GUCY1B1 PTPRR HAS2

5.90e-0635514811M45758
ToppCellfacs-MAT-Fat-3m-Myeloid-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 ITGAX WDFY4 RYR1 SBNO2 MCTP1 UCP2

1.31e-0616414871250876abd7311f86730e5b9c03c3610cc2ff6d3
ToppCellfacs-MAT-Fat-3m-Myeloid|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 ITGAX WDFY4 RYR1 SBNO2 MCTP1 UCP2

1.31e-061641487fa0d77b648cde5e42b9394e877168c80de238bde
ToppCellfacs-MAT-Fat-3m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 ITGAX WDFY4 RYR1 SBNO2 MCTP1 UCP2

1.31e-061641487b81498c3934e0d52bf0329dc745e02966f9d8613
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CPAMD8 SFRP4 PI16 JAM2 HMCN1 LMO2 PTPRR

2.09e-06176148752af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CA12 GALNT14 FRAS1 TFAP2A TFAP2B SCN2A ATP6V0D2

3.23e-0618814871d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEAD2 NPR1 IFIT1 SEMA4C JAM2 LMO2 PTPRR

3.35e-06189148792319bef1f00d6048ba8f9f8b5c6dbb896686b74
ToppCelldroplet-Kidney-nan-18m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEAD2 NPR1 PI16 IFIT1 JAM2 LMO2 PTPRR

3.72e-061921487144503af50274eaed5cf6effa892c640eab28663
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEAD2 NPR1 PI16 IFIT1 JAM2 LMO2 PTPRR

3.72e-061921487c96736bb3a6bb052678b1b078f7823063ca69e6d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 GALNT14 FRAS1 ARHGEF28 CUBN PTPRJ ACOT11

3.85e-06193148782e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCelldroplet-Kidney-nan-21m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR1 PI16 SEMA4C JAM2 LMO2 PTPRR EXOC3L4

3.85e-0619314870e39b6c8e7382e61a9891f6c7e3df2a859788219
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 GALNT14 FRAS1 ARHGEF28 EVC PTPRJ ACOT11

3.98e-06194148793c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KNTC1 TOPBP1 ECT2 ITGAX NCAPG2 LIG1 ATP6V0D2

4.12e-061951487c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCellPCW_10-12-Hematologic_Myeloid|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK8 ITGAX WDFY4 RYR1 MCTP1 UCP2 TREM1

4.12e-0619514876352cd749091cfdbf5cce3c354fa57883cc513e8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 GALNT14 FRAS1 ARHGEF28 EVC PTPRJ ACOT11

4.26e-0619614876ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 GALNT14 FRAS1 ARHGEF28 EVC PTPRJ ACOT11

4.26e-061961487eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CPAMD8 NPR1 IFIT1 JAM2 MCTP1 LMO2 GUCY1B1

4.86e-06200148766f7e8ee63c828f17468e79a4b816346b33e8980
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 FRAS1 TFAP2A HMCN1 SCN2A ATP6V0D2

6.60e-06137148685b3a98039c1f68addad0334aa5b2584f6045aaa
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC|GW10 / Sample Type, Dataset, Time_group, and Cell type.

DOCK8 CUBN IFIT1 HMCN1 LMO2 ATP6V0D2

1.15e-0515114864533bccc996395f74b16af939ce79b6fe253c073
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related|GW10 / Sample Type, Dataset, Time_group, and Cell type.

DOCK8 CUBN IFIT1 HMCN1 LMO2 ATP6V0D2

1.15e-051511486edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RTTN EVC WDFY4 RYR1 LIG1 MCTP1

1.39e-051561486af47a4b17342bdb3cb62d7e2d52a81168e588629
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TDRD5 FRAS1 CDHR2 NWD2 ANKAR ATP6V0D2

1.72e-051621486bf886e22ff2a20353499004b53f25fb9e6574896
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 RTTN ECT2 ITGAX WDFY4 NCAPG2

1.78e-0516314868dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 RTTN ECT2 ITGAX WDFY4 NCAPG2

1.78e-051631486fd243ca223079033be480a24817a399f281fa4d4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 NPR1 PI16 JAM2 MCTP1 LMO2

1.90e-051651486a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

FRAS1 ARHGEF28 NBEA TFAP2A PTPRR PDE8B

2.57e-0517414867d2f802f493f19a068e097b2909a9000e2160266
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK8 ITGAX WDFY4 RYR1 UCP2 ATP6V0D2

3.01e-051791486716856b2c7c660bf5ce00e63efeda6ed121f2baa
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GALNT14 BRINP3 ARHGEF28 MCTP1 ANKMY2 DMD

3.01e-0517914861ac79c82c52fa95bb4e170ab20fec0f648db2134
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK8 ITGAX WDFY4 RYR1 UCP2 ATP6V0D2

3.20e-051811486090e89b506d945e123e647d08947e9649a65ce7c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 TFAP2A HMCN1 ACOT11 SCN2A ATP6V0D2

3.20e-051811486e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CA12 GALNT14 FRAS1 ARHGEF28 CUBN SCN2A

3.30e-0518214869d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

ARHGEF28 BTNL8 CDHR2 IGF2BP3 PTPRR SCN2A

3.41e-05183148615d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 FRAS1 TFAP2A HMCN1 ACOT11 SCN2A

3.41e-0518314862e831a4d99c6f983793df71c0994124c943c6da9
ToppCellPBMC-Mild-cDC_9|Mild / Compartment, Disease Groups and Clusters

UNC13B IFIT1 JAM2 IFIH1 IGF2BP3 CES3

3.51e-0518414862e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|metastatic_Brain / Location, Cell class and cell subclass

NPR1 PI16 CUBN JAM2 LMO2 PTPRR

3.62e-051851486ad52970e88e8947ef256095bd4b40229b912d58a
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

GALNT14 KNTC1 ECT2 NCAPG2 IGF2BP3 KCNQ5

3.62e-0518514869766216b41ee62bbac4caa25cb98ec5627a24075
ToppCelldroplet-Kidney-nan-3m-Endothelial-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR1 IFIT1 SEMA4C JAM2 LMO2 EXOC3L4

3.73e-051861486d72cdbb6d79ab33a5823c42e93c2ba566244f64c
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

CPAMD8 FRAS1 NBEA CUBN TFAP2A PTPRR

3.84e-051871486ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

TEAD2 RTTN IGF2BP3 PTPRJ LMO2 HAS2

3.84e-0518714867e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

CA12 GALNT14 FRAS1 ARHGEF28 CUBN SCN2A

3.84e-051871486d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellP07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NPR1 ARHGEF28 PI16 JAM2 MCTP1 PTPRR

3.96e-0518814865bc1537e079c7435196c163bff5f639ea392a33a
ToppCelldroplet-Kidney-nan-3m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEAD2 NPR1 PI16 JAM2 LMO2 PTPRR

3.96e-05188148667c04f446fa4528b13a381622e88eb1f314cc6d5
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK8 ITGAX WDFY4 RYR1 MCTP1 TREM1

3.96e-0518814868fc15c8b78fdd1a578e34325011bc5a87a8aab31
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEAD2 NPR1 PI16 JAM2 LMO2 PTPRR

3.96e-05188148603a7f6538cfddc230c0eab10c3613929addd7e33
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

UNC13B BRINP3 NWD2 KCNQ5 PTPRR VPS13A

4.08e-051891486a75226616340045b581d08429d2e123e041dee55
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEAD2 NPR1 IFIT1 JAM2 LMO2 PTPRR

4.20e-051901486cb8798839c27f307955fcc94a1ee40bca95b8e99
ToppCellmetastatic_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ|B_lymphocytes / Location, Cell class and cell subclass

GALNT14 IGF2BP3 LMO2 PDE8B UCP2 DYNLL1

4.20e-051901486c5c80a6b9087821a2e07250fa90bcd3505f103b6
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEAD2 NPR1 IFIT1 JAM2 LMO2 PTPRR

4.20e-0519014865bf3d0beee69879c95265d07fba023626a7cc808
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

UNC13B BRINP3 NWD2 KCNQ5 PTPRR VPS13A

4.20e-05190148649e09cdb843b3d889a06a811aa5affae68b25a75
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK8 ITGAX WDFY4 MCTP1 UCP2 TREM1

4.32e-051911486a5ee4d72b2311c8fa98ff73adc2499debb2014f1
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK8 ITGAX WDFY4 RYR1 MCTP1 UCP2

4.32e-051911486c383ae386bc53e73a683a9543c7dfed2a65257c5
ToppCelldroplet-Kidney-nan-3m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR1 IFIT1 SEMA4C JAM2 LMO2 PTPRR

4.32e-051911486dc58d45fafd224d2761aefbe0ce79f66b50c1c03
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEAD2 NPR1 PI16 JAM2 LMO2 PTPRR

4.45e-051921486c0498baa2556e1597c00df2e75efadeb14bd34ef
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 BRINP3 TFAP2A SCN2A UCP2 ATP6V0D2

4.45e-05192148640f44ac4ab673ee6156abdd2074a60b9de3281ad
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 NPR1 IFIT1 JAM2 MCTP1 LMO2

4.45e-051921486c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEAD2 NPR1 PI16 JAM2 LMO2 PTPRR

4.45e-051921486cb906b10cad76e978c5c0b966215368ebef30e51
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

KNTC1 RTTN FANCM ECT2 NCAPG2 LIG1

4.58e-0519314864b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 GALNT14 FRAS1 ARHGEF28 CUBN PTPRJ

4.58e-0519314863866667dd221612589ae50f5c52f73a183a49ce6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 FRAS1 BRINP3 TFAP2A SCN2A UCP2

4.72e-051941486be869e186386d03ebb670971dd24fa656b4b0edf
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 FRAS1 BRINP3 TFAP2A SCN2A UCP2

4.72e-0519414864d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK8 ITGAX WDFY4 RYR1 MCTP1 UCP2

4.72e-051941486846b4170544cdf58b536fb7a5fd34b79b0b17993
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte1_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK8 ITGAX WDFY4 RYR1 MCTP1 UCP2

4.72e-051941486fad22d5cf62016cad979e6943e357106d8d2a4b4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 GALNT14 FRAS1 ARHGEF28 PTPRJ ACOT11

4.85e-0519514866477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

UNC13B BRINP3 KCNQ5 PTPRR SCN2A VPS13A

4.85e-0519514862e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellC_05|World / shred on cell type and cluster

CDHR2 TMEM54 IFIT1 IFIH1 NLN PTPRR

4.99e-051961486bf4dfb460a153dbafb2b9b12b360c8757cec22cd
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT14 CPAMD8 FRAS1 EFCAB13 PTPRJ SCN2A

5.14e-0519714867e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ARHGEF28 SPEF2 RTTN SEMA4C TBC1D32 VPS13A

5.14e-051971486e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GALNT14 FRAS1 OBSCN USP31 KCNQ5 ACOT11

5.14e-0519714861e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ITGAX WDFY4 RYR1 FMNL3 MCTP1 TREM1

5.43e-051991486744b63fba33b176ab7dde11646ccb313665505f7
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NPR1 IFIT1 JAM2 MCTP1 LMO2 GUCY1B1

5.58e-052001486bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CA12 ARHGEF28 MORC4 TFAP2A ACOT11 DOP1B

5.58e-052001486ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NPR1 SPEF2 IFIT1 JAM2 IGF2BP3 LMO2

5.58e-052001486b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

NPR1 IFIT1 JAM2 MCTP1 LMO2 GUCY1B1

5.58e-052001486432384faeade8e609154fab3d96c955a8ec868dd
ToppCellParenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SFRP4 PI16 OBSCN PAQR8 THBS4 EGFR

5.58e-0520014868a4c210a3130f7baedf15ecbc0f4903b97da0352
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGEF28 SPATA12 NBEA TFAP2A ACOT11 DOP1B

5.58e-05200148685c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 BRINP3 ACOT11 SCN2A ATP6V0D2

7.68e-051311485d706405453408fbcfcabb1c7702b80f9e649ffca
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEAD2 EVC FANCM KCNQ5 BBS12

1.05e-041401485e442c46979d725ec82f525a001c46d971fcade4d
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EFCAB13 TSC2 FANCM TBC1D32 EXOC3L4

1.24e-041451485b17699f7f98d2361a4d26c26f52db05e7ff69dff
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FKBP6 SCN2A ATP6V0D2 TBC1D21 DOP1B

1.24e-0414514859964d6d3769be2f35d86268fe044cecd1d5a1616
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GALNT14 NBEA CUBN TFAP2A TFAP2B

1.36e-0414814855983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|367C / Donor, Lineage, Cell class and subclass (all cells)

FANCM FMNL3 ATXN7L3B ZER1 DOP1B

1.41e-04149148541f28138bde45d0b814e116837e5a32b5e80d54a
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KNTC1 ARHGEF28 EVC RYR1 NWD2

1.74e-0415614852cd007b423c2395c5ce331902e7f27c805755eb3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTTN ECT2 ITGAX WDFY4 NCAPG2

1.80e-041571485ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 FRAS1 TFAP2A HMCN1 SCN2A

1.85e-0415814857960337d87afecf2692ab65e5991f052ceddfacc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 BRINP3 PTPRJ SCN2A ATP6V0D2

1.85e-041581485debebc8534a80e5500051f6fd352dc201585968d
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 FRAS1 SNX19 KLHL8 BBS12

1.90e-0415914854000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 FRAS1 SNX19 KLHL8 BBS12

1.90e-0415914857619d0d49738dd08daf01b42664691a5323aa793
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ARHGEF28 JAM2 EGFR LMO2 ARHGEF37

1.90e-0415914850dccc4275b9b4f8554dd556da7218e130bff8fd1
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP43 ITGAX WDFY4 RYR1 MCTP1

1.96e-0416014855c28121916a12dbc22ef2421040bdc9148a40b78
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP43 ITGAX WDFY4 RYR1 MCTP1

1.96e-041601485b7093678987575f2f99d648821d31b4a37075aca
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 DOCK8 PTPRJ SCN2A ATP6V0D2

1.96e-0416014851e210e526ea4d84fc58a798a26c0929bcb69fd89
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

RYR1 IGF2BP3 KCNQ5 PTPRR DMD

2.14e-04163148519c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 ARHGEF28 PTPRJ SCN2A ATP6V0D2

2.20e-041641485d847d509bb1791638032ade6755d8164586b5bd5
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

SIN3B OBSCN PTPN23 CFAP43 ACOT11

2.33e-04166148532d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KNTC1 FRAS1 SNX19 KLHL8 BBS12

2.33e-041661485bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CA12 ARHGEF28 PTPRJ SCN2A ATP6V0D2

2.33e-0416614856fe8db8d45177a78605681f22e04fa8d0594f2df
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KNTC1 FRAS1 SNX19 KLHL8 BBS12

2.33e-0416614855e3b998d740b24f790fad37350d704ca0ea10b77
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UNC13B TEAD2 EVC PTPRR KDSR

2.39e-041671485f01b96173deda0239fa482989873cf308e49d48c
ToppCellControl-Lymphocytic_B-B_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK8 WDFY4 KCNQ5 PTPRJ UCP2

2.39e-041671485a15a70d3837b31cc83a2a9e3f1bbfd77a95f2312
ToppCellControl-Lymphocytic_B|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK8 WDFY4 KCNQ5 PTPRJ UCP2

2.39e-041671485956da82394fd6a9f45fc2031796f12cc889542cd
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UNC13B TEAD2 EVC PTPRR KDSR

2.39e-0416714855fc85a05124cd2324e1b8ff940193880f83cd8af
ComputationalGenes in the cancer module 65.

NPR1 NPR2 GUCY1B1

4.94e-0510823MODULE_65
ComputationalGenes in the cancer module 445.

NPR1 NPR2 GUCY1B1

1.82e-0415823MODULE_445
Drugbarium iodide

IFNA4 IFNA7 IFNA10

1.07e-0641483CID000083684
DrugB132

IFNA4 IFNA7 IFNA10

2.67e-0651483CID002734031
DrugAC1O3GBZ

KNTC1 RELA IFNA4 IFNA7 IFNA10

3.48e-06361485CID006327751
Drugp203

ARFGEF1 IFNA4 IFNA7 IFNA10

4.89e-06181484CID000019228
DrugHCV-371

IFNA4 IFNA7 IFNA10

5.31e-0661483CID003013096
DrugMurabutida

ITGAX IFNA4 IFNA7 IFNA10 IFIH1

8.56e-06431485CID005362018
DrugYfrkd

IFNA4 IFNA7 IFNA10

9.24e-0671483CID000129984
Drugridostin

UNC13B CUBN IFNA4 IFNA7 IFNA10 IFIH1 EGFR

1.10e-051161487CID011979623
DrugAC1LAD6M

IFNA4 IFNA7 IFNA10

1.47e-0581483CID000511663
Drug1hiv

IFNA4 IFNA7 IFNA10

1.47e-0581483CID005479205
DrugChebi:36708

IFNA4 IFNA7 IFNA10

1.47e-0581483CID011966289
DrugO4-[3-[(1S)-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxyphenyl)-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] O1-[3-[(1R)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] (Z)-2-chlorobut-2-enedioate

IFNA4 IFNA7 IFNA10

1.47e-0581483CID010011375
DrugHMPV

IFNA4 IFNA7 IFNA10 IFIH1

1.95e-05251484CID004444603
DrugTelaprevir

IFNA4 IFNA7 IFNA10

2.20e-0591483CID003010818
Drugboceprevir

IFNA4 IFNA7 IFNA10

2.20e-0591483CID010324367
Drugpipobroman

IFNA4 IFNA7 IFNA10

3.12e-05101483CID000004842
DrugAC1NRA8N

COPB1 ARFGEF1 NBEA TFAP2A EGFR SCN2A AP1G2 DYNLL1

3.40e-051891488CID005287758
DrugNMMA

NPR1 NPR2 IFNA4 IFNA7 IFNA10 GUCY1B1

3.47e-05941486CID000170607
DrugNocodazole [31430-18-9]; Down 200; 13.2uM; PC3; HT_HG-U133A

SIN3B COPA NBEA EGFR GUCY1B1 AP1G2 HAS2 ZNF654

3.53e-0519014887145_DN
DrugS-nitrosoacetylcysteine

NPR1 NPR2 RYR1 GUCY1B1

3.59e-05291484CID000122058
DrugErythrityl Tetranitrate

NPR1 NPR2

4.20e-0521482DB01613
Drugflesinoxan

IFNA4 IFNA7 IFNA10

4.27e-05111483CID000057347
DrugSC-57099B

IFNA4 IFNA7 IFNA10

4.27e-05111483CID000178079
DrugRapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A

NUDT18 ERN1 GRIN1 TFAP2A IFIH1 CES3 ZER1 DOP1B

4.40e-0519614882681_UP
Drugstrontium chromate

KNTC1 NPR2 ERN1 RYR1 LIG1 GUCY1B1

4.64e-05991486CID000024599
DrugL(-)-vesamicol hydrochloride [112709-59-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A

ZNF573 LZTR1 ARFGEF1 MTERF4 SEMA4C VPS13D EGFR LMO2

4.73e-0519814886497_DN
DrugAmiloride hydrochloride dihydrate [17440-83-4]; Up 200; 13.2uM; HL60; HG-U133A

TSC2 MTERF4 SBNO2 ACOT11 VPS13A AP1G2 ZNF654 HTT

4.90e-0519914881970_UP
Drugimidazoquinoline

RELA IFNA4 IFNA7 IFNA10 IFIH1 TREM1

5.20e-051011486CID005351568
Drugcasopitant

IFNA4 IFNA7 IFNA10

5.67e-05121483CID009917021
Drug2,4,5,2',5'-pentachlorobiphenyl

CA12 KNTC1 TEAD2 BRINP3 TOPBP1 RELA MSH4 ECT2 NCAPG2 RYR1 USP31 IFIH1 TBC1D32 NWD2 MCTP1 KCNQ5 PTPRJ SCN2A LTN1 DMD ARHGEF37 HAS2 TBC1D21

5.70e-05144114823ctd:C009828
DrugExcitatory Amino Acid Agonists

RELA GRIN1 TFAP2A TFAP2B

6.06e-05331484ctd:D018690
DrugR 842

IFNA4 IFNA7 IFNA10

7.34e-05131483CID000130714
DrugAC1O52EF

IFNA4 IFNA7 IFNA10

7.34e-05131483CID006450817
Drug2-fluoroadenine arabinoside

TOPBP1 RELA ITGAX IFNA4 IFNA7 IFNA10 LIG1

8.00e-051581487CID000003367
DrugLanicemine

IFNA4 IFNA7 IFNA10

9.30e-05141483CID003038485
Druggunacin

IFNA4 IFNA7 IFNA10

9.30e-05141483CID000198547
DiseasePolydactyly

FRAS1 EVC TFAP2A TFAP2B TRIM32 BBS12

2.17e-051171416C0152427
Diseaseautosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)

VPS13D VPS13A

6.78e-0531412DOID:0111611 (implicated_via_orthology)
Diseasebody weight

UNC13B KNTC1 BRINP3 COPB1 RTTN VIRMA TFAP2B SBNO2 GHSR NBAS IGF2BP3 KCNQ5 PTPRJ PTPRR CAPZA3 DMD TBC1D21

1.14e-04126114117EFO_0004338
DiseaseClinodactyly

TFAP2A TFAP2B

1.35e-0441412C4551485
DiseaseClinodactyly of fingers

TFAP2A TFAP2B

1.35e-0441412C0265610
DiseaseColorectal Carcinoma

UNC13B CPAMD8 SFRP4 OBSCN ARFGEF1 CUBN LIG1 KCNQ5 EGFR INTS13 VPS13A DMD

1.46e-0470214112C0009402
DiseaseCiliopathies

EVC TSC2 CCDC39 TRIM32 BBS12

1.90e-041101415C4277690
Diseasethrombocytopenia (implicated_via_orthology)

PTPRJ KDSR

4.69e-0471412DOID:1588 (implicated_via_orthology)
DiseaseEpilepsy, Cryptogenic

ERN1 TSC2 SCN2A VDAC2

6.55e-04821414C0086237
DiseaseAwakening Epilepsy

ERN1 TSC2 SCN2A VDAC2

6.55e-04821414C0751111
DiseaseAura

ERN1 TSC2 SCN2A VDAC2

6.55e-04821414C0236018
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

ERN1 TSC2 RELA ASB15 RYR1

7.42e-041481415C0279702
Diseasedilated cardiomyopathy (is_marker_for)

OBSCN TFAP2A DMD

8.61e-04391413DOID:12930 (is_marker_for)
DiseaseCongenital small ears

FRAS1 EVC TFAP2A

9.97e-04411413C0152423
Diseasesleep disorder (implicated_via_orthology)

TFAP2A TFAP2B

1.21e-03111412DOID:535 (implicated_via_orthology)
Diseasequality of life during menstruation measurement, acne

FMNL3 NLN

1.21e-03111412EFO_0003894, EFO_0009366
DiseaseIntellectual Disability

DOCK8 RTTN PTPN23 NBEA SIN3A GRIN1 KCNQ5 HTT

1.43e-034471418C3714756
DiseaseAlzheimer disease, dementia

TFAP2A CFAP46

1.45e-03121412MONDO_0001627, MONDO_0004975
DiseaseAbnormality of refraction

GALNT14 EVC NBEA PCDHA3 TFAP2B THBS4 KCNQ5 PTPRR SCN2A DYNLL1

1.52e-0367314110HP_0000539
Diseasecongenital left-sided heart lesions

FRAS1 CFAP43 ASB15

1.58e-03481413EFO_0005938
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

SIN3B SIN3A CAPZA3

1.68e-03491413DOID:0060037 (implicated_via_orthology)
DiseaseEpilepsy

ERN1 TSC2 SCN2A VDAC2

1.89e-031091414C0014544
Diseasetrimethylamine-N-oxide measurement

CUBN INTS13

1.99e-03141412EFO_0010541
DiseaseHuntington's disease (is_marker_for)

SIN3A UCP2 HTT

2.10e-03531413DOID:12858 (is_marker_for)
Diseaseglycerate measurement

MCTP1 HMCN1

2.29e-03151412EFO_0021029
Diseasegliosarcoma

LZTR1 EGFR

2.60e-03161412C0206726
Diseaseankle brachial index

NBAS DMD

2.60e-03161412EFO_0003912
DiseaseBardet-Biedl syndrome 1 (disorder)

TRIM32 BBS12

2.94e-03171412C2936862
DiseaseBrain Ischemia

RELA UCP2 DYNLL1

3.00e-03601413C0007786
DiseaseCerebral Ischemia

RELA UCP2 DYNLL1

3.00e-03601413C0917798
DiseaseSquamous cell carcinoma

DOCK8 TSC2 EGFR VDAC2

3.01e-031241414C0007137
Diseaseprogression free survival, ovarian carcinoma

FMNL3 NBAS

3.30e-03181412EFO_0001075, EFO_0004920
DiseaseBardet-Biedl syndrome

TRIM32 BBS12

3.30e-03181412cv:C0752166
Diseasehypertension (implicated_via_orthology)

NPR1 PTPRJ UCP2 DYNLL1

3.37e-031281414DOID:10763 (implicated_via_orthology)
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

RELA EGFR

3.68e-03191412DOID:2876 (is_marker_for)
Diseasemyocardial infarction (implicated_via_orthology)

RYR1 TREM1 VDAC2

3.92e-03661413DOID:5844 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
QGVEETNIELLVCNY

PI16

151

Q6UXB8
QESVDQLSLILSYEC

TDRD5

926

Q8NAT2
VNLQVEDSGLYQCVI

TREM1

101

Q9NP99
QNEAEYLRVVLLCAL

CAPZA3

111

Q96KX2
DQAIQCVAEILGETY

EXOC3L4

626

Q17RC7
LQERFVQAALSYIAC

BRINP3

251

Q76B58
NYALSCNLREELVAV

CFAP43

1586

Q8NDM7
KCDAYLQQTQELVIL

CCNT2

121

O60583
VLLLACNISETIQAY

CEACAM4

51

O75871
CAEKTDYVNLIQELA

CDNF

161

Q49AH0
AVECLYNNIVIETLL

TBC1D32

511

Q96NH3
AIAQEIYVDLIEDSC

ATXN7L3B

16

Q96GX2
SITGYVDRDIQLLCQ

BTNL8

141

Q6UX41
LCVTELKNNVAAYLD

ARHGEF37

281

A1IGU5
IACIFSIQLERDAYV

ARFGEF1

986

Q9Y6D6
IYGSCLDVELQQRAV

AP1G2

551

O75843
LNCLLVAVRANNYEI

ASB15

381

Q8WXK1
VCAAVTALQNYLTEA

TFAP2A

391

P05549
ECQVAVLLDLARSYQ

CFAP46

2501

Q8IYW2
VYADTIKDLLANCAI

ACOT11

186

Q8WXI4
IILTCIAEDQYANAF

ARMH3

396

Q5T2E6
VDNICQSVAIYQAAL

APPBP2

301

Q92624
QVVTLLNDLYTCFDA

NPR2

881

P20594
DILQIINCLTTIYDR

DMD

3146

P11532
QVVTLLNDLYTCFDA

NPR1

896

P16066
AVQVAYITQVNEDCV

BBS12

451

Q6ZW61
CAALTALQNYLTEAL

TFAP2B

411

Q92481
EIYALENTLQVLNSC

CCDC39

691

Q9UFE4
YDNVNSCLLSEVEIK

NWD2

1036

Q9ULI1
LLINSDIVCEQDIYE

LMO2

136

P25791
TAADLNLVLYVCETV

EDC4

1286

Q6P2E9
VANTICKADAENLIY

ECT2

791

Q9H8V3
ACQVEVRLLLAYNSS

INTS4

906

Q96HW7
EQTLVQSNICLYIDK

ITGAX

646

P20702
VLCALTEANVQYAAV

PTPN23

626

Q9H3S7
LTEEDVLNCQKTIYN

INTS13

486

Q9NVM9
LTDNIQCEIFQVLYE

AK6

116

Q9Y3D8
EDLVCKLADISINYV

LTN1

591

O94822
ILTNQDQQICAYLEE

ARHGEF28

1221

Q8N1W1
ILYDIAQCENKDVIA

ANKAR

806

Q7Z5J8
ELYQQLNDLEACVIQ

IFNA10

111

P01566
DQYVFLNQCVLDIVR

PTPRJ

1286

Q12913
AALVDVNVYLIVAIC

PCDHA3

691

Q9Y5H8
VIEQYCTLTILDDTQ

FRAS1

2861

Q86XX4
IYAIQEVCVSVQNIL

MCTP1

881

Q6DN14
CRQYIEASVDLQNVL

LZTR1

566

Q8N653
NVCYVVLAVFLSEQD

NUDT18

41

Q6ZVK8
SDICQYIAIVIATNE

NLRP11

846

P59045
DCYLQNVAISTLLEV

DOP1B

806

Q9Y3R5
IESKLDCLLDIYQQV

KCNQ5

616

Q9NR82
VLLVAAYEAERQLCL

FANCM

56

Q8IYD8
SQEQLLALETALYCT

CA12

246

O43570
SVECATQALEKYNIE

DYNLL1

21

P63167
LYAACILQVELVARA

KLHL8

141

Q9P2G9
EISQANVICIVYAVN

RHOT1

71

Q8IXI2
ACIDIYFVQVVIVAN

OR4K17

191

Q8NGC6
NSSIIACYNELIQIE

PDE8B

241

O95263
AAQCYIDLIIKESDN

COPB1

281

P53618
IICEATQIIDYLEQT

GDAP1

86

Q8TB36
VIAEVYSQICQVSEE

PPM1N

391

Q8N819
ELYQQLNDLEACVIQ

IFNA7

111

P01567
ISLKDYQNTEEVCQL

KNTC1

671

P50748
DLVVTQCGNAIYRVL

GUCY1B1

226

Q02153
LYEEEICLLQSQISE

KRT82

256

Q9NSB4
QVVTAVEYQEAILAC

JAM2

36

P57087
LCDNLVTLETLVYEA

NBAS

881

A2RRP1
VLDSLLVQYGVVESC

IGF2BP3

96

O00425
IKVNNTLTLECEAYA

HMCN1

2686

Q96RW7
EVLVISVNECDNYTI

PTPRR

516

Q15256
YTQQILQEELCLSVI

GALNT14

466

Q96FL9
NCALLEQAYAVVSAL

OBSCN

5856

Q5VST9
ICTLSQLEAILLDYQ

PAQR8

291

Q8TEZ7
TIALCYGEQALIIDQ

FKBP6

236

O75344
LINYEAISAATACLQ

CUBN

1036

O60494
NNCEVVLGNLEITYV

EGFR

56

P00533
EDLACQKISYNVTDL

SERPINA2

46

P20848
INQSKAIDYEACDLV

CDHR2

876

Q9BYE9
VQLRVNYCLLDSDQV

HTT

1456

P42858
VEELLCNLNSILYDT

DOCK8

1596

Q8NF50
EIAQISQYCNLVSFV

GHSR

296

Q92847
AIELCAATLQEYVEQ

ERN1

641

O75460
EIAEAQQLITICREY

COPA

1046

P53621
LDVLVDYLSFAQCSV

FMNL3

136

Q8IVF7
CDLETNSEINKLIIY

CLLU1

36

Q5K131
TQDTCVALQALAEYA

CPAMD8

1416

Q8IZJ3
LAEAQTYLDKVENTC

IFIT1B

111

Q5T764
LNKTVALCIAAYQED

HAS2

81

Q92819
CNIVIRYGLVTNEIA

IFIH1

801

Q9BYX4
YCEATLLQQLVRSIA

ANKMY2

276

Q8IV38
CEAISKLQENYIAAE

EFCAB13

461

Q8IY85
YVAAADIQDLVSCLA

IFRD2

256

Q12894
VPVANDCYIVLLDQD

MAN2B2

581

Q9Y2E5
LAEAQTYLDKVENIC

IFIT1

111

P09914
RATEAVVALCQELYF

EVC

511

P57679
QIFSVSEDCLVLNVY

CES3

116

Q6UWW8
VDASEIQVQVCLYAF

LIG1

646

P18858
VLNCIDRLNVYTTAA

RYR1

486

P21817
VVLCISVDVSQDYNQ

KDSR

86

Q06136
ACSETYVVNLLLVSN

OR4C16

186

Q8NGL9
QKTCQVLIIDDSLYE

FREM3

1961

P0C091
KSLEQLSDVILQCYE

RTTN

1836

Q86VV8
YSVCAEILDQIVDLS

SPEF2

426

Q9C093
YLLNIAEVQAVSRCD

TRIM32

226

Q13049
EKILLLSYVCNTQAE

TBC1D21

146

Q8IYX1
ALSELAALCYVIAFQ

RGPD2

311

P0DJD1
VIEELSCVRSNNYVQ

MTERF4

51

Q7Z6M4
NTLYEILTEQVCTQV

NBEA

811

Q8NFP9
QTLDAETDVLCAVLY

NEPRO

56

Q6NW34
LSQTYLECVQAQAVI

MORC4

151

Q8TE76
IVSDEICVQVTDLYL

SIN3A

1011

Q96ST3
VSDDVCLKVVELYLN

SIN3B

901

O75182
ALSALQLEAITYACQ

SBNO2

246

Q9Y2G9
QLEAITYACQQHEVL

SBNO2

251

Q9Y2G9
LEYIEQLCIAEFSTV

MSH4

251

O15457
DTQELLLCTAYVFEV

TEAD2

416

Q15562
ELYQQLNDLEACVIQ

IFNA4

111

P05014
LSAICEYQLEEIQRV

SEMA4C

326

Q9C0C4
ESRLIEAYVIQCQAE

BROX

176

Q5VW32
EAYVIQCQAEAQEVT

BROX

181

Q5VW32
CDTDIQNKLYADIVL

ACTRT1

286

Q8TDG2
NESENYEALLECVII

NCAPG2

111

Q86XI2
ENCLQALADVEVKYI

NLN

86

Q9BYT8
LELYLDCIQVDSVHN

THBS4

141

P35443
NAIVNCAELVTYDLI

UCP2

186

P55851
ICDRLVNEYVELVNA

ZER1

46

Q7Z7L7
YICASVEFLQTVANV

VPS13A

1506

Q96RL7
QFTDLDLQCEIISYI

ZNF573

96

Q86YE8
DAVALQYCVVNILSV

TMEM54

51

Q969K7
TCQRYLQAAISLDIA

SPATA12

81

Q7Z6I5
CIQYEVLEAAQLAIE

REXO5

546

Q96IC2
LAIEQYEELVDVNCS

SFRP4

56

Q6FHJ7
DQDSQYVCFTLVLQV

RNF25

56

Q96BH1
DVSVVNNYSECKALI

SCN2A

1376

Q99250
IQYLQATDCVRLSLQ

WDFY4

256

Q6ZS81
QVFVDQCYQLLRTAT

ZNF654

316

Q8IZM8
YQKVCEDLDTSVNLA

VDAC2

206

P45880
QYSQLVLNVCETLQE

NUP188

1226

Q5SRE5
QCAVLDLALDTIKQY

UNC13B

1351

O14795
LSVTEAQDKILYCLQ

SNX19

736

Q92543
NRDTQETLLCIAYVF

TEAD4

401

Q15561
EQAVAAIVCTFQEYA

S100A3

6

P33764
QLSEDEVCTQTAYIL

USP31

746

Q70CQ4
DYDLNAVRLCFQVTV

RELA

151

Q04206
VNIAEAAAQNVYCLR

TOPBP1

1451

Q92547
EYVTSILQSLCDQDI

VIRMA

1281

Q69YN4
LEILAYCISDTAVQE

ZFYVE26

1491

Q68DK2
EVSLQVLDAVVCYNC

TSC2

216

P49815
QDYINLVQCETLEDL

ATP6V0D2

31

Q8N8Y2
FIAVENIDSYCVLIS

VPS13D

4266

Q5THJ4
LSVCEDLISSQVYAI

GRIN1

76

Q05586