Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

DOCK1 MIA3 RIPOR2 CCDC42 SCG2 E2F7 ID1 MACF1 ERVK-19 KDR ACTN1 FLOT1 KIF20B CCDC136 EPAS1

6.48e-0514836715GO:0048646
GeneOntologyBiologicalProcesscilium assembly

CCDC42 IFT74 CNTRL SYNE2 FNBP1L CFAP53 HYDIN BBS10

9.29e-05444678GO:0060271
GeneOntologyBiologicalProcessepithelial cell differentiation

KRT2 KRT6B RIPOR2 KRT6C IFT74 E2F7 ID1 KDR RFX6 HYDIN EPAS1

1.04e-048706711GO:0030855
GeneOntologyBiologicalProcessmicrotubule-based process

RIPOR2 CCDC42 IFT74 CNTRL SYNE2 MACF1 KIF3C APP SGO1 CFAP53 HYDIN KIF20B

1.37e-0410586712GO:0007017
GeneOntologyBiologicalProcesscilium organization

CCDC42 IFT74 CNTRL SYNE2 FNBP1L CFAP53 HYDIN BBS10

1.50e-04476678GO:0044782
GeneOntologyBiologicalProcesscell-cell fusion

DOCK1 RIPOR2 ERVK-19 FLOT1

1.69e-0485674GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

DOCK1 RIPOR2 ERVK-19 FLOT1

1.69e-0485674GO:0000768
GeneOntologyBiologicalProcessregulation of JNK cascade

HIPK3 TAOK3 LMNB1 APP COPS5

1.78e-04161675GO:0046328
GeneOntologyBiologicalProcesssyncytium formation

DOCK1 RIPOR2 ERVK-19 FLOT1

2.02e-0489674GO:0006949
GeneOntologyBiologicalProcessepithelial cell development

KRT2 IFT74 ID1 KDR HYDIN EPAS1

2.39e-04269676GO:0002064
GeneOntologyBiologicalProcessregulation of receptor internalization

RNF216 USP46 APP FLOT1

2.59e-0495674GO:0002090
GeneOntologyBiologicalProcessprotein-containing complex localization

GRIPAP1 LMNB1 IFT74 CEP112 RNF216 USP46

2.85e-04278676GO:0031503
GeneOntologyBiologicalProcessnegative regulation of endothelial cell apoptotic process

SCG2 ID1 KDR

2.97e-0440673GO:2000352
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

RIPOR2 CCDC42 IFT74 CNTRL SYNE2 FNBP1L CFAP53 HYDIN BBS10

3.03e-04670679GO:0120031
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

KRT2 KRT6B KRT6C MACF1

3.04e-0499674GO:0045104
GeneOntologyBiologicalProcessintermediate filament-based process

KRT2 KRT6B KRT6C MACF1

3.15e-04100674GO:0045103
GeneOntologyBiologicalProcesscell projection assembly

RIPOR2 CCDC42 IFT74 CNTRL SYNE2 FNBP1L CFAP53 HYDIN BBS10

3.57e-04685679GO:0030031
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

DOCK1 RIPOR2 SIPA1L1 SYNE2 ID1 MACF1 KDR CGNL1 FNBP1L APP FLOT1 BBS10

4.01e-0411896712GO:0044087
GeneOntologyBiologicalProcessJNK cascade

HIPK3 TAOK3 LMNB1 APP COPS5

4.62e-04198675GO:0007254
GeneOntologyBiologicalProcessepithelial cell migration

DOCK1 KRT2 MIA3 SCG2 ID1 MACF1 KDR

4.96e-04432677GO:0010631
GeneOntologyBiologicalProcessregulation of cell junction assembly

DOCK1 SIPA1L1 MACF1 KDR APP FLOT1

4.99e-04309676GO:1901888
GeneOntologyBiologicalProcessepithelium migration

DOCK1 KRT2 MIA3 SCG2 ID1 MACF1 KDR

5.17e-04435677GO:0090132
GeneOntologyBiologicalProcesscell-substrate junction organization

LAMTOR2 MACF1 KDR ACTN1

5.36e-04115674GO:0150115
GeneOntologyBiologicalProcessameboidal-type cell migration

DOCK1 KRT2 MIA3 LAMTOR2 SCG2 ID1 MACF1 KDR

5.46e-04577678GO:0001667
GeneOntologyBiologicalProcesstissue migration

DOCK1 KRT2 MIA3 SCG2 ID1 MACF1 KDR

5.61e-04441677GO:0090130
GeneOntologyBiologicalProcessactin filament-based transport

SYNE2 FNBP1L

5.61e-0411672GO:0099515
GeneOntologyBiologicalProcessprotein deubiquitination

USP12 USP46 MINDY2 COPS5

7.34e-04125674GO:0016579
GeneOntologyCellularComponentintermediate filament cytoskeleton

KRT2 KRT6B LMNB1 KRT6C DTNA SYNE2 MACF1

2.32e-05263687GO:0045111
GeneOntologyCellularComponentcentrosome

CCDC42 MTUS1 IFT74 CEP112 CNTRL CIR1 ID1 SGO1 FLOT1 CFAP53 KIF20B

3.56e-057706811GO:0005813
GeneOntologyCellularComponentmicrotubule organizing center

CCDC42 MTUS1 IFT74 CEP112 CNTRL CIR1 ID1 SGO1 FLOT1 CFAP53 KIF20B

1.72e-049196811GO:0005815
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KRT2 KRT6B LMNB1 KRT6C MTUS1 MACF1 KIF3C ACTN1 CFAP53 KIF20B

6.22e-048996810GO:0099513
GeneOntologyCellularComponentdense core granule

SCG2 ACTN1 APP

8.07e-0456683GO:0031045
GeneOntologyCellularComponentintermediate filament

KRT2 KRT6B LMNB1 KRT6C MACF1

8.64e-04227685GO:0005882
DomainIntermediate_filament_CS

KRT2 KRT6B LMNB1 KRT6C

6.03e-0563634IPR018039
DomainActinin_actin-bd_CS

SYNE2 MACF1 ACTN1

6.17e-0523633IPR001589
DomainSpectrin

SYNE2 MACF1 ACTN1

6.17e-0523633PF00435
DomainACTININ_2

SYNE2 MACF1 ACTN1

6.17e-0523633PS00020
DomainACTININ_1

SYNE2 MACF1 ACTN1

6.17e-0523633PS00019
DomainKeratin_2_head

KRT2 KRT6B KRT6C

7.04e-0524633IPR032444
DomainKeratin_2_head

KRT2 KRT6B KRT6C

7.04e-0524633PF16208
DomainKeratin_II

KRT2 KRT6B KRT6C

9.00e-0526633IPR003054
DomainFilament

KRT2 KRT6B LMNB1 KRT6C

9.64e-0571634SM01391
DomainIF

KRT2 KRT6B LMNB1 KRT6C

1.02e-0472634PS00226
DomainFilament

KRT2 KRT6B LMNB1 KRT6C

1.07e-0473634PF00038
DomainSpectrin_repeat

SYNE2 MACF1 ACTN1

1.26e-0429633IPR002017
DomainIF

KRT2 KRT6B LMNB1 KRT6C

1.26e-0476634IPR001664
DomainSpectrin/alpha-actinin

SYNE2 MACF1 ACTN1

1.69e-0432633IPR018159
DomainSPEC

SYNE2 MACF1 ACTN1

1.69e-0432633SM00150
DomainCH

SYNE2 MACF1 ACTN1

1.38e-0365633SM00033
DomainCH

SYNE2 MACF1 ACTN1

1.70e-0370633PF00307
Domain-

SYNE2 MACF1 ACTN1

1.78e-03716331.10.418.10
DomainCH

SYNE2 MACF1 ACTN1

1.92e-0373633PS50021
DomainCH-domain

SYNE2 MACF1 ACTN1

2.08e-0375633IPR001715
DomainSH3

DOCK1 MIA3 MACF1 FNBP1L

6.08e-03216634PS50002
DomainSH3_domain

DOCK1 MIA3 MACF1 FNBP1L

6.49e-03220634IPR001452
DomainKinesin_motor_CS

KIF3C KIF20B

8.44e-0341632IPR019821
DomainKinesin-like_fam

KIF3C KIF20B

9.25e-0343632IPR027640
DomainKINESIN_MOTOR_1

KIF3C KIF20B

9.67e-0344632PS00411
Domain-

KIF3C KIF20B

9.67e-03446323.40.850.10
DomainKinesin_motor_dom

KIF3C KIF20B

9.67e-0344632IPR001752
DomainKinesin

KIF3C KIF20B

9.67e-0344632PF00225
DomainKINESIN_MOTOR_2

KIF3C KIF20B

9.67e-0344632PS50067
DomainKISc

KIF3C KIF20B

9.67e-0344632SM00129
Pubmed

A human MAP kinase interactome.

DOCK1 HIPK3 KMT2C RIPOR2 CNTRL MACF1 ACTN1 CGNL1 COPS5 EPAS1

4.21e-08486691020936779
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KRT2 KRT6B LMNB1 KRT6C CEP112 DTNA CNTRL SYNE2 MARF1 MACF1 KDR ACTN1 FNBP1L SGO1 MINDY2

1.18e-071442691535575683
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

GRIPAP1 IFT74 DTNA E2F7 MACF1 CGNL1 FNBP1L SGO1 KIF20B

2.44e-0658869938580884
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

KMT2C MIA3 RIPOR2 SYNE2 MARF1 MACF1 ACTN1

3.60e-0632269726514267
Pubmed

Phosphorylated pVEGFR2/KDR receptor expression in uveal melanomas: relation with HIF2α and survival.

KDR EPAS1

3.88e-06269221984395
Pubmed

The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth.

USP12 USP46

3.88e-06269225855980
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

KMT2C TAOK3 MIA3 RIPOR2 CEP112 SIPA1L1 CNTRL TTC14 MACF1 SDF4 GOLM1

8.94e-061084691111544199
Pubmed

Strong Correlation Between mRNA Expression Levels of HIF-2α, VEGFR1, VEGFR2 and MMP2 in Laryngeal Carcinoma.

KDR EPAS1

1.16e-05369227075652
Pubmed

Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay.

KRT6B KRT6C

1.16e-05369229357356
Pubmed

EMMPRIN promotes melanoma cells malignant properties through a HIF-2alpha mediated up-regulation of VEGF-receptor-2.

KDR EPAS1

1.16e-05369220824203
Pubmed

Essential Role of CFAP53 in Sperm Flagellum Biogenesis.

CCDC42 CFAP53

1.16e-05369234124066
Pubmed

Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms.

KRT6B KRT6C

1.16e-0536927543104
Pubmed

Expression of vascular endothelial growth factor and Flk-1 in developing and glucocorticoid-treated mouse lung.

KDR EPAS1

1.16e-05369210813585
Pubmed

The intracellular domain of amyloid precursor protein interacts with flotillin-1, a lipid raft protein.

APP FLOT1

1.16e-05369216480949
Pubmed

LGI3 interacts with flotillin-1 to mediate APP trafficking and exosome formation.

APP FLOT1

1.16e-05369220461023
Pubmed

The role of flotillins in regulating aβ production, investigated using flotillin 1-/-, flotillin 2-/- double knockout mice.

APP FLOT1

1.16e-05369224465508
Pubmed

Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha ) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1).

KDR EPAS1

1.16e-05369212464608
Pubmed

Alzheimer's beta-amyloid peptide blocks vascular endothelial growth factor mediated signaling via direct interaction with VEGFR-2.

KDR APP

1.16e-05369219818105
Pubmed

EMMPRIN promotes angiogenesis through hypoxia-inducible factor-2alpha-mediated regulation of soluble VEGF isoforms and their receptor VEGFR-2.

KDR EPAS1

2.32e-05469219837976
Pubmed

A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme.

USP12 USP46

2.32e-05469227650958
Pubmed

Id1 modulates endothelial progenitor cells function through relieving the E2-2-mediated repression of FGFR1 and VEGFR2 in vitro.

ID1 KDR

2.32e-05469226476925
Pubmed

Hypoxic-ischemic gene expression profile in the isolated variant of biliary atresia.

KDR EPAS1

2.32e-05469226510548
Pubmed

WDR20 prevents hepatocellular carcinoma senescence by orchestrating the simultaneous USP12/46-mediated deubiquitination of c-Myc.

USP12 USP46

2.32e-05469239432777
Pubmed

HIV-1 Tat interacts with and regulates the localization and processing of amyloid precursor protein.

APP FLOT1

2.32e-05469224312169
Pubmed

Epigenetic Studies in the Male APP/BIN1/COPS5 Triple-Transgenic Mouse Model of Alzheimer's Disease.

APP COPS5

2.32e-05469235269588
Pubmed

The dystrophia myotonica WD repeat-containing protein DMWD and WDR20 differentially regulate USP12 deubiquitinase.

USP12 USP46

2.32e-05469233844468
Pubmed

Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration.

ID1 KDR

2.32e-05469221068842
Pubmed

Lactate dehydrogenase 5 expression in non-Hodgkin B-cell lymphomas is associated with hypoxia regulated proteins.

KDR EPAS1

2.32e-05469219021062
Pubmed

E1-mediated recruitment of a UAF1-USP deubiquitinase complex facilitates human papillomavirus DNA replication.

USP12 USP46

2.32e-05469224850727
Pubmed

Kidney development and gene expression in the HIF2alpha knockout mouse.

KDR EPAS1

2.32e-05469217342756
Pubmed

WDR20 regulates shuttling of the USP12 deubiquitinase complex between the plasma membrane, cytoplasm and nucleus.

USP12 USP46

2.32e-05469230466959
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

NWD2 DTNA SIPA1L1 USP12 MACF1 ACTN1 FLOT1

2.35e-0543069732581705
Pubmed

Ubiquitin-dependent degradation of Id1 and Id3 is mediated by the COP9 signalosome.

ID1 COPS5

3.86e-05569215451666
Pubmed

UAF1 is a subunit of multiple deubiquitinating enzyme complexes.

USP12 USP46

3.86e-05569219075014
Pubmed

WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex.

USP12 USP46

3.86e-05569220147737
Pubmed

CCDC38 is required for sperm flagellum biogenesis and male fertility in mice.

CCDC42 CFAP53

3.86e-05569235587122
Pubmed

Pachyonychia Congenita

KRT6B KRT6C

3.86e-05569220301457
Pubmed

COPS5 (Jab1) protein increases β site processing of amyloid precursor protein and amyloid β peptide generation by stabilizing RanBP9 protein levels.

APP COPS5

3.86e-05569223926111
Pubmed

Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.

KRT2 KRT6B MACF1 ACTN1 FLOT1

4.01e-0519169533762435
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

KRT2 MIA3 MTUS1 DTNA SYNE2 USP12 SDF4 USP46 APP SGO1

4.05e-051049691027880917
Pubmed

Ephrin-As, Eph receptors and integrin α3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells.

KRT2 LAMB4 KRT6B KRT6C CNTRL

4.64e-0519769523686814
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

NEXMIF SYNE2 MARF1 MACF1 ACTN1

4.64e-0519769520811636
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

KRT2 MIA3 LAMTOR2 CEP112 SYNE2 CIR1 MACF1 SDF4 GOLM1 APP FLOT1

4.66e-051297691133545068
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

GRIPAP1 MIA3 LMNB1 MTUS1 IFT74 SIPA1L1 CNTRL CGNL1 FLOT1

4.68e-0585369928718761
Pubmed

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development.

KDR EPAS1

8.09e-0576929113979
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

GRIPAP1 MACF1 KIF3C APP

9.80e-0512069431413325
Pubmed

The USP1-UAF1 complex interacts with RAD51AP1 to promote homologous recombination repair.

USP12 USP46

1.08e-04869227463890
Pubmed

HIV-1 upregulates VEGF in podocytes.

KDR EPAS1

1.08e-04869218443354
Pubmed

Arg/Abl-binding protein, a Z-body and Z-band protein, binds sarcomeric, costameric, and signaling molecules.

ACTN1 FLOT1

1.08e-04869220886612
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

GRIPAP1 SIPA1L1 CNTRL CIR1 ACTN1 APP CCDC136

1.23e-0456069721653829
Pubmed

Regulation of histone H2A and H2B deubiquitination and Xenopus development by USP12 and USP46.

USP12 USP46

1.38e-04969221183687
Pubmed

Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice.

KDR EPAS1

1.38e-04969212053176
Pubmed

The transcription factor MEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expression of angiopoietin 1 and VEGF.

KDR EPAS1

1.73e-041069210395786
Pubmed

Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.

LMNB1 SYNE2

1.73e-041069228533284
Pubmed

WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1).

USP12 USP46

1.73e-041069224145035
Pubmed

Identification of differential protein interactors of lamin A and progerin.

KRT6B LMNB1 SYNE2

1.82e-045569321327095
Pubmed

RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers.

KRT2 KRT6B KRT6C

2.03e-045769331862882
Pubmed

N6-Methyladenosine modification of the TRIM7 positively regulates tumorigenesis and chemoresistance in osteosarcoma through ubiquitination of BRMS1.

KRT2 KRT6C

2.11e-041169232853985
Pubmed

Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia.

KDR ACTN1

2.11e-041169224355925
Pubmed

The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development.

KRT2 KRT6B MACF1

2.24e-045969326371508
Pubmed

p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes.

LMNB1 SYNE2

2.53e-041269228595999
Pubmed

Maternal corticosterone exposure in the mouse has sex-specific effects on placental growth and mRNA expression.

KDR STAR

2.53e-041269222919064
Pubmed

Sostdc1 defines the size and number of skin appendage placodes.

KRT2 ID1

2.53e-041269222509524
Pubmed

iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications.

KDR EPAS1

2.53e-041269231118412
Pubmed

New consensus nomenclature for mammalian keratins.

KRT2 KRT6B KRT6C

2.73e-046369316831889
Pubmed

Human colostrum: identification of minor proteins in the aqueous phase by proteomics.

BTD GOLM1 ACTN1 APP

3.10e-0416269416502470
Pubmed

A yeast two-hybrid screen reveals that osteopontin associates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain.

GRIPAP1 COPS5 EPAS1

3.41e-046869322779921
Pubmed

SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.

LMNB1 SYNE2

3.48e-041469219874786
Pubmed

Mechanical regulation of glycolysis via cytoskeleton architecture.

LMNB1 ACTN1

3.48e-041469232051585
Pubmed

SnoN facilitates ALK1-Smad1/5 signaling during embryonic angiogenesis.

ID1 KDR

4.01e-041569224019535
Pubmed

A molecular mechanism underlying the neural-specific defect in torsinA mutant mice.

LMNB1 SYNE2

4.01e-041569220457914
Pubmed

Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.

KRT2 KRT6B KRT6C MACF1 ACTN1 FLOT1

4.20e-0448869631324722
Pubmed

Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F.

KRT2 KRT6B KRT6C

4.56e-047569331527668
Pubmed

Hague (Hag). A new mouse hair mutation with an unstable semidominant allele.

KRT2 KRT6B

4.57e-041669212399393
Pubmed

Restoring BMP4 expression in vascular endothelial progenitors ameliorates maternal diabetes-induced apoptosis and neural tube defects.

ID1 KDR

5.18e-041769233060561
Pubmed

Loss of PiT-1 results in abnormal endocytosis in the yolk sac visceral endoderm.

LAMTOR2 KDR

5.18e-041769225138534
Pubmed

Location of transient ectodermal progenitor potential in mouse development.

ID1 KDR

5.18e-041769224131634
Pubmed

Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS.

USP12 USP46

5.81e-041869230410068
Pubmed

Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development.

KDR EPAS1

6.49e-041969216787915
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK1 HIPK3 KMT2C MIA3 DTNA TTC14 MACF1 FNBP1L APP COPS5

6.83e-041489691028611215
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

TTC14 MACF1

7.20e-042069221689717
Pubmed

ABCE1 is a highly conserved RNA silencing suppressor.

LMNB1 MACF1 SDF4 FLOT1

7.38e-0420469425659154
Pubmed

Proteomic analysis of a detergent-resistant membrane skeleton from neutrophil plasma membranes.

ACTN1 FLOT1

7.95e-042169212202484
Pubmed

Mendelian randomization and experimental IUGR reveal the adverse effect of low birth weight on lung structure and function.

ID1 KDR

7.95e-042169233372189
Pubmed

Novel interaction partners of Bardet-Biedl syndrome proteins.

FLOT1 EPAS1

7.95e-042169218000879
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

MIA3 MTUS1 SIPA1L1 MACF1

8.07e-0420969436779422
Pubmed

Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling.

USP12 USP46

8.73e-042269226811477
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

KRT2 KRT6B KRT6C CNTRL SDF4 ACTN1

8.94e-0456469621565611
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

IFT74 SCG2 SIPA1L1 MACF1 RNF216 ACTN1 APP FLOT1 COPS5

9.64e-04128569935914814
Pubmed

Cellular redox sensor HSCARG negatively regulates the translesion synthesis pathway and exacerbates mammary tumorigenesis.

KRT2 USP12 ACTN1 COPS5

9.93e-0422169431796584
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

DOCK1 KMT2C IFT74 BTD KDR SPATA22 USP46 GINS1 HYDIN

1.01e-03129369915342556
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

DOCK1 IFT74 CNTRL

1.05e-0310069325807483
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

KMT2C SIPA1L1 SYNE2 MACF1

1.06e-0322569412168954
Pubmed

Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation.

ID1 KDR

1.13e-032569216887829
Pubmed

Functional proteomics mapping of a human signaling pathway.

HIPK3 MACF1 RNF216 SDF4 COPS5 EPAS1

1.14e-0359169615231748
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

NWD2 MTUS1 MACF1

1.15e-0310369310574462
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

DOCK1 SIPA1L1 APP PRPF39

1.19e-0323269425515538
Pubmed

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.

MACF1 SDF4 ACTN1 APP

1.25e-0323569428378594
Pubmed

Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizing BRCA1 mRNA.

KRT6B KRT6C ACTN1

1.28e-0310769332989256
Pubmed

Bardet-Biedl Syndrome Overview

IFT74 BBS10

1.32e-032769220301537
InteractionMTNR1B interactions

KMT2C MIA3 RIPOR2 SYNE2 MARF1 MACF1 ACTN1

3.57e-07135687int:MTNR1B
InteractionUSP12 interactions

USP12 SDF4 USP46 APP SGO1

3.09e-0667685int:USP12
InteractionDES interactions

KRT2 KRT6B KRT6C DTNA SPATA22 LONRF3

1.55e-05158686int:DES
InteractionSYNE3 interactions

MIA3 LMNB1 IFT74 SIPA1L1 SYNE2 MACF1 SDF4 CGNL1 APP

1.76e-05444689int:SYNE3
InteractionCTNNA1 interactions

DTNA SIPA1L1 MACF1 ACTN1 APP FLOT1 CCDC180 COPS5

2.14e-05347688int:CTNNA1
InteractionKRT24 interactions

KRT2 KRT6B KRT6C COPS5

3.30e-0554684int:KRT24
InteractionPHTF1 interactions

KRT2 KRT6B KRT6C

4.02e-0520683int:PHTF1
InteractionCSRP1 interactions

CNTRL MACF1 ACTN1 APP

6.87e-0565684int:CSRP1
InteractionVIM interactions

KRT2 KRT6B LMNB1 KRT6C IFT74 CNTRL ACTN1 APP FLOT1 COPS5 KIF20B

7.30e-058046811int:VIM
Cytoband12q13.13

KRT2 KRT6B KRT6C

1.39e-046768312q13.13
Cytoband12q21.2

E2F7 BBS10

4.04e-042068212q21.2
Cytoband15q21.3

CGNL1 MINDY2

1.25e-033568215q21.3
GeneFamilyKeratins, type II

KRT2 KRT6B KRT6C

3.78e-0527443609
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF3C KIF20B

5.60e-0346442622
GeneFamilyUbiquitin specific peptidases

USP12 USP46

8.20e-0356442366
CoexpressionCUI_TCF21_TARGETS_2_DN

HIPK3 KMT2C RIPOR2 GVINP1 MTUS1 DTNA TTC14 USP12 MACF1 USP46 APP MINDY2 EPAS1

2.12e-078546713M1533
CoexpressionGSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP

KMT2C MIA3 MTUS1 TTC14 MINDY2 GINS1 KIF20B

7.74e-07199677M9850
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DOCK1 TAOK3 LMNB1 SIPA1L1 SYNE2 ID1 USP12 MACF1 FNBP1L APP GINS1 KIF20B

1.57e-068566712M4500
CoexpressionCUI_TCF21_TARGETS_2_DN

HIPK3 KMT2C RIPOR2 MTUS1 DTNA TTC14 USP12 MACF1 USP46 APP MINDY2 EPAS1

2.29e-068886712MM1018
CoexpressionGSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_DN

MIA3 LAMTOR2 TTC14 SDF4 GOLM1 EPAS1

1.21e-05199676M316
CoexpressionAIZARANI_LIVER_C29_MVECS_2

ID1 ACTN1 CGNL1 OMD APP FLOT1 EPAS1

1.52e-05313677M39128
CoexpressionFAN_EMBRYONIC_CTX_NSC_2

LMNB1 CNTRL ACTN1 SGO1 GINS1 KIF20B

2.94e-05233676M39036
CoexpressionLAKE_ADULT_KIDNEY_C24_ENDOTHELIAL_CELLS_AEA_AND_DVR

MTUS1 ID1 MACF1 APP EPAS1

4.44e-05152675M39243
CoexpressionGSE6259_FLT3L_INDUCED_VS_WT_SPLENIC_DC_33D1_POS_DN

LMNB1 E2F7 LONRF3 OMD BBS10

6.19e-05163675M6722
CoexpressionGSE14415_INDUCED_TREG_VS_TCONV_UP

E2F7 SGO1 COPS5 GINS1 EPAS1

9.63e-05179675M2959
CoexpressionHEVNER_CORTEX_RADIAL_GLIA_PROGENITORS

DOCK1 IFT74 BTD CNTRL SGO1 GINS1 KIF20B

1.17e-04432677MM419
CoexpressionKARLSSON_TGFB1_TARGETS_DN

MTUS1 SYNE2 ID1 GOLM1 ACTN1

1.40e-04194675M2081
CoexpressionPYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP

LMNB1 E2F7 FNBP1L PRPF39 GINS1

1.44e-04195675M13736
CoexpressionGSE30971_WBP7_HET_VS_KO_MACROPHAGE_4H_LPS_STIM_DN

BTD SIPA1L1 MARF1 GINS1 EPAS1

1.51e-04197675M8726
CoexpressionGSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN

HEPACAM MIA3 SGO1 CFAP53 CCDC136

1.58e-04199675M3070
CoexpressionGSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_IRF8_KO_UP

NEXMIF SYNE2 ID1 APP GINS1

1.62e-04200675M8099
CoexpressionGSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP

DOCK1 LMNB1 SDF4 APP FLOT1

1.62e-04200675M7020
CoexpressionGSE3982_MAST_CELL_VS_TH2_DN

LMNB1 GVINP1 OMD KIF20B EPAS1

1.62e-04200675M5456
CoexpressionGSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP

DOCK1 HIPK3 TTC14 RNF216 APP

1.62e-04200675M8500
CoexpressionGSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP

RIPOR2 SIPA1L1 KIF3C ACTN1 FNBP1L

1.62e-04200675M9205
CoexpressionANDERSON_BLOOD_CN54GP140_ADJUVANTED_WITH_GLA_AF_AGE_18_45YO_7DY_UP

TAOK3 DTNA STAR

1.71e-0442673M41209
CoexpressionKARLSSON_TGFB1_TARGETS_DN

MTUS1 SYNE2 ID1 GOLM1 ACTN1

1.99e-04209675MM1058
CoexpressionAtlasB cells, B.Pl.AA4-.BM, CD138+ AA4.1- CD43+, Bone marrow, avg-2

DOCK1 MTUS1 SYNE2 USP46 FNBP1L LONRF3 APP SGO1

3.28e-05394678GSM777030_500
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_1000

DOCK1 HIPK3 LMNB1 CNTRL USP12 PRPF39 KIF20B

9.50e-05339677gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k5
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

RIPOR2 IFT74 DTNA NEXMIF CNTRL SYNE2 E2F7 MACF1 GOLM1 FNBP1L SGO1 KIF20B

1.06e-0410606712facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#5_top-relative-expression-ranked_1000

DOCK1 HIPK3 LMNB1 MACF1 PRPF39

1.19e-04152675gudmap_developingKidney_e15.5_S-shaped body_1000_k5
CoexpressionAtlasDevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#5_top-relative-expression-ranked_1000

DOCK1 LMNB1 USP12 PRPF39

1.44e-0484674gudmap_developingKidney_e15.5_Endothelial cells_1000_k5
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Endothelial-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

E2F7 ID1 KDR FNBP1L CFAP53 EPAS1

2.69e-07176676a3f27b5d7edf2d396c085efbe35305cfa0afa565
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMNB1 E2F7 KDR SGO1 KIF20B EPAS1

5.22e-07197676a41420d4b6d502c2f594c054c7efbb5d4eac83ff
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LMNB1 CNTRL SYNE2 E2F7 SGO1 KIF20B

5.54e-0719967698575fcce726589e93fbb4df1aab03e57cb56076
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LMNB1 CNTRL SYNE2 E2F7 SGO1 KIF20B

5.54e-07199676be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 CEP112 SYNE2 ACTN1 CGNL1 EPAS1

5.70e-07200676032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KMT2C SYNE2 MACF1 KDR APP EPAS1

5.70e-07200676dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 CEP112 SYNE2 ACTN1 CGNL1 EPAS1

5.70e-0720067668fce28690246895fd33354b30960ebcc31aa4cc
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 CEP112 SYNE2 ACTN1 CGNL1 EPAS1

5.70e-07200676376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SYNE2 MACF1 KDR APP MINDY2 EPAS1

5.70e-0720067679e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 CEP112 SYNE2 ACTN1 CGNL1 EPAS1

5.70e-072006767fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 CEP112 SYNE2 ACTN1 CGNL1 EPAS1

5.70e-07200676878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCellHematolymphoid-Endothelial|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 CEP112 SYNE2 ACTN1 CGNL1 EPAS1

5.70e-072006767136936d05ab344a560cf159684c881063b5430d
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GVINP1 ID1 KDR CGNL1 EPAS1

4.45e-06161675a60ef3f390f56bb05b687b17986fe6382f69f260
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell-Endo|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GVINP1 ID1 KDR CGNL1 EPAS1

4.59e-061626750bdb1e5ba33e162bec1acb28256c1405a7658ee5
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GVINP1 ID1 KDR CGNL1 EPAS1

4.59e-061626755799a602ef8d83925907e8e34532428be7330228
ToppCelldroplet-Spleen-SPLEEN-30m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTUS1 ID1 ACTN1 APP FLOT1

5.48e-06168675c0ff30e2c47005514131a0866cf10a1c228128fc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LMNB1 E2F7 SGO1 GINS1 KIF20B

6.50e-0617467584da9faff088d05233183b425385beb054c92d1b
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMNB1 CEP112 E2F7 SGO1 KIF20B

6.50e-0617467572df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMNB1 CEP112 E2F7 SGO1 KIF20B

6.50e-06174675c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LMNB1 E2F7 SGO1 GINS1 KIF20B

6.68e-06175675876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4|Striatum / BrainAtlas - Mouse McCarroll V32

LMNB1 E2F7 SGO1 GINS1 KIF20B

6.87e-06176675d70fdc7bc48719776ed1e7c01118385e3a21623f
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1|Striatum / BrainAtlas - Mouse McCarroll V32

LMNB1 E2F7 SGO1 GINS1 KIF20B

6.87e-06176675a84361308e5e96f3a30246cd29e109c321ee65bf
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMNB1 KDR SGO1 KIF20B EPAS1

6.87e-061766758385435074cc5235b7af7424974f609388fc2cff
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RIPOR2 SYNE2 MARF1 MACF1 MINDY2

7.06e-06177675d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GVINP1 SYNE2 ID1 KDR EPAS1

7.06e-06177675ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RIPOR2 SYNE2 MARF1 MACF1 MINDY2

7.06e-06177675f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GVINP1 SYNE2 ID1 KDR EPAS1

7.06e-06177675f471f7747d6e8db7546899019af9508f48a14f89
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GVINP1 SYNE2 ID1 KDR EPAS1

7.06e-06177675cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

RIPOR2 SYNE2 MARF1 MACF1 MINDY2

7.06e-061776756978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RIPOR2 SYNE2 MARF1 MACF1 MINDY2

7.06e-06177675936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RIPOR2 SYNE2 MARF1 MACF1 MINDY2

7.06e-06177675d5aeda113afaa2425874394610344570c9078478
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LMNB1 E2F7 SGO1 GINS1 KIF20B

7.66e-06180675401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LMNB1 E2F7 SGO1 GINS1 KIF20B

7.66e-06180675f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMNB1 KDR SGO1 KIF20B EPAS1

7.66e-06180675b35a8c6169f4b548b912af005e92ae7c6596f376
ToppCelldroplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GVINP1 SYNE2 KDR FNBP1L EPAS1

7.87e-0618167592d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

SYNE2 ID1 KDR APP EPAS1

7.87e-06181675c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB4 LMNB1 ID1 KDR SGO1

8.30e-0618367552af3c943116073c8ddd207b664342960b88929b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NWD2 SIPA1L1 ACTN1 HYDIN ANKRD18B

8.30e-061836751645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MTUS1 TRPM3 SYNE2 ID1 CGNL1

8.52e-0618467542ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NWD2 SIPA1L1 ACTN1 HYDIN ANKRD18B

8.52e-0618467534e316ad8e7b8667cd8ad61397281802a252744f
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

LMNB1 E2F7 SGO1 GINS1 KIF20B

8.52e-061846756b2449ac65a2322aa0479fba0d89828f243aabbe
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

LMNB1 E2F7 SGO1 GINS1 KIF20B

8.52e-06184675e90622b82fa7f16a1faaf7a4724c958f2d83341d
ToppCellCOPD-Endothelial-VE_Capillary_A|COPD / Disease state, Lineage and Cell class

ID1 KDR FNBP1L APP EPAS1

8.52e-061846755f4f7775d488ececf086c71441defecbee9d8a9c
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ID1 KDR CGNL1 FNBP1L EPAS1

8.75e-061856757f46ea82a663181957f88e4e83114aef8a78820c
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE2 ID1 KDR CGNL1 EPAS1

8.75e-0618567503df43e9c2ce4ec24ffed8e4e2993f94ba951c8b
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ID1 KDR CGNL1 FNBP1L EPAS1

8.75e-06185675956fb0043c0c3e4e5c4d6f58ff95faf6209c380e
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE2 ID1 KDR CGNL1 EPAS1

8.75e-06185675dbdbd6593cd98550238519746bb45fbf0617550b
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

LMNB1 E2F7 SGO1 GINS1 KIF20B

8.75e-061856759766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Endo|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE2 ID1 KDR CGNL1 EPAS1

8.75e-06185675de2c24719946d5a37a982d816776cea7f3984c49
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE2 ID1 KDR CGNL1 EPAS1

8.98e-06186675422d24e3e1a9397bb7d5c7ef75de2fd7ae8e136d
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ID1 KDR CGNL1 FNBP1L EPAS1

8.98e-06186675a58c9d1567da0961e0e295a156773d2252ee5a1a
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE2 ID1 KDR CGNL1 EPAS1

8.98e-0618667565da0666a10a59f8cc379589860a2e98fe487754
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE2 ID1 KDR CGNL1 EPAS1

8.98e-06186675dc84fef1ca2f5d5d818b76a3321559e87d1c4a4d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LMNB1 E2F7 SGO1 GINS1 KIF20B

9.21e-061876759351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LMNB1 E2F7 SGO1 GINS1 KIF20B

9.21e-06187675057569c9437219ecc396aa6e673b1178a2273837
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LMNB1 CNTRL E2F7 SGO1 KIF20B

9.21e-0618767573931a5ea73799095daff100b5f18853c57c74dc
ToppCellIPF-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

ID1 KDR FNBP1L APP EPAS1

9.70e-06189675ea3aa3ef38f1d405bb527ae383cd12c551a3dd6f
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

TRPM3 ID1 ACTN1 CGNL1 EPAS1

9.70e-0618967575c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

SYNE2 ID1 KDR FNBP1L EPAS1

9.95e-06190675a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

LMNB1 CEP112 E2F7 GINS1 KIF20B

9.95e-06190675d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell3'-Child04-06-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MTUS1 ID1 KDR APP EPAS1

9.95e-06190675ec6b8e2852e1cce0217ff61243defe98b2351640
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LMNB1 E2F7 SGO1 GINS1 KIF20B

1.02e-0519167515dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTUS1 ID1 KDR GOLM1 FNBP1L

1.02e-05191675df8cdbc26443e55a203cbafa21b0952a2a55b9bf
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LMNB1 E2F7 SGO1 GINS1 KIF20B

1.02e-0519167545c15f5ce4a207ac944bed65d45f06c1657d1a6d
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

SYNE2 ID1 KDR APP EPAS1

1.02e-05191675c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

TRPM3 SIPA1L1 E2F7 ACTN1 CGNL1

1.05e-05192675c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

SYNE2 ID1 KDR APP EPAS1

1.05e-051926758a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCellDividing_Macrophages-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

LMNB1 E2F7 SGO1 GINS1 KIF20B

1.05e-05192675741bd0c2b0a7ce3fcb1610ce8bdacaf9a803c212
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMNB1 E2F7 SGO1 GINS1 KIF20B

1.05e-05192675e8d47504b744040a762ec9b670a66cc060b2ae86
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE2 TTC14 GOLM1 CGNL1 APP

1.05e-05192675ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

LMNB1 CEP112 SGO1 GINS1 KIF20B

1.07e-051936754b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellRV-09._Endothelium_I|World / Chamber and Cluster_Paper

SYNE2 ID1 KDR FNBP1L EPAS1

1.07e-05193675e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCellPND14-Endothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ID1 KDR FNBP1L APP EPAS1

1.10e-05194675cee89d4340738f09d07a159cd6aeee4300776988
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ID1 KDR FNBP1L APP EPAS1

1.10e-051946756115c20ffe414378508f3879e67815b6062341a7
ToppCellPND14-Endothelial-Endothelial_blood-vessel|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ID1 KDR FNBP1L APP EPAS1

1.10e-0519467532962060d80f3edffbe9f0ecad3000c3a9817865
ToppCellPND28-Endothelial-Endothelial_blood-vessel|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ID1 KDR FNBP1L APP EPAS1

1.10e-051946756317e9cdf96eb020f84d50bf41f803db5c9c04a0
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC14 ID1 MACF1 KDR EPAS1

1.10e-05194675e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LMNB1 E2F7 SGO1 GINS1 KIF20B

1.10e-05194675f9070035553bc68106a9e0bdf4b507715a138aba
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTUS1 KDR FNBP1L APP EPAS1

1.10e-05194675f159ef8541d75a4e98468947f231bb463bec922c
ToppCellfacs-Heart-LA-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ID1 KDR CGNL1 FNBP1L EPAS1

1.10e-0519467533cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCellPND28-Endothelial|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ID1 KDR FNBP1L APP EPAS1

1.10e-05194675b592c713204db7ae2f34a54f2d03d13834593c57
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ID1 KDR FNBP1L APP EPAS1

1.10e-05194675c6cee7d15af76f9a60d7f414ef0bcc1735c47b7a
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

E2F7 LONRF3 SGO1 GINS1 KIF20B

1.13e-05195675c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LMNB1 E2F7 SGO1 GINS1 KIF20B

1.13e-05195675b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

LMNB1 E2F7 SGO1 GINS1 KIF20B

1.13e-05195675764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LMNB1 E2F7 SGO1 GINS1 KIF20B

1.13e-05195675926eb3fc5d028be936885bea0654a77db3107234
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MTUS1 ID1 KDR APP EPAS1

1.13e-05195675b0979c1b5e4576468b8fe4e9027650859e598b34
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KMT2C MIA3 SCG2 MACF1 RFX6

1.13e-051956753e519cffa6144a62b06124642a14c9ff39b76554
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LMNB1 E2F7 SGO1 GINS1 KIF20B

1.13e-0519567556d8734d020b3da08a5aa9e67999706a9e023a99
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KMT2C MIA3 SCG2 MACF1 RFX6

1.13e-051956757796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMNB1 E2F7 SGO1 KIF20B EPAS1

1.16e-0519667520383d576708b7e4bfce3e9fe40548cce496e3cb
ToppCellCOVID-19-lung-Proliferative_fibroblast|lung / Disease (COVID-19 only), tissue and cell type

LMNB1 E2F7 SGO1 GINS1 KIF20B

1.16e-051966752ce8a787f2731faa913d20342d73041d59468f27
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LMNB1 OMD SGO1 GINS1 KIF20B

1.16e-05196675df366d76ea55f49e349d622effa57c1535df8400
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LMNB1 E2F7 SGO1 GINS1 KIF20B

1.16e-051966751d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCellfacs-Skin-Telogen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTUS1 MACF1 ACTN1 CGNL1 APP

1.16e-05196675c936014125b2ed5f796221b74acb77b8f8359875
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LMNB1 E2F7 SGO1 GINS1 KIF20B

1.16e-0519667573f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MTUS1 ID1 KDR CGNL1 EPAS1

1.16e-05196675889c9fed857f64664ca1f47fcec9fecb15ed103c
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMNB1 E2F7 SGO1 KIF20B EPAS1

1.16e-051966750644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MTUS1 ID1 KDR APP EPAS1

1.19e-05197675f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LMNB1 E2F7 SGO1 GINS1 KIF20B

1.19e-0519767584ed777cdba569200a3ef1654d8a12f17fcfb7f1
Drugmant-GTP

KRT6B LMNB1 KRT6C SYNE2 ACTN1

3.36e-0750665CID000128647
DrugAC1L9LMC

KRT6B KRT6C DTNA SYNE2 ACTN1

4.28e-0683665CID000448113
Drugirinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A

TAOK3 LMNB1 SIPA1L1 USP12 FNBP1L KIF20B

1.03e-051716667535_DN
Drugdithranol

KRT2 KRT6B KRT6C

1.84e-0518663CID000002202
DrugLevopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; MCF7; HT_HG-U133A

KRT6B CEP112 DTNA BTD MACF1 MINDY2

2.17e-051956663543_UP
DrugLuteolin [491-70-3]; Down 200; 14uM; MCF7; HT_HG-U133A

DOCK1 TAOK3 DTNA BTD CNTRL ID1

2.17e-051956665004_DN
DrugDioxybenzone [131-53-3]; Down 200; 16.4uM; HL60; HT_HG-U133A

HIPK3 LMNB1 DTNA KIF3C USP46 FNBP1L

2.23e-051966663101_DN
DrugChlormezanone [80-77-3]; Down 200; 14.6uM; MCF7; HT_HG-U133A

LMNB1 DTNA SCG2 SIPA1L1 CNTRL LONRF3

2.29e-051976665697_DN
DrugPhenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; MCF7; HT_HG-U133A

LMNB1 BTD SIPA1L1 MARF1 USP46 APP

2.36e-051986665298_DN
Drug5140203; Up 200; 15uM; MCF7; HT_HG-U133A_EA

IFT74 DTNA CNTRL RNF216 APP MINDY2

2.36e-05198666908_UP
DrugQuinethazone [73-49-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A

HIPK3 KRT6B MIA3 DTNA MACF1 LONRF3

2.36e-051986664351_DN
Drugaltizide

ID1 APP

4.95e-054662CID000002122
Drugplakin

KRT6B KRT6C SYNE2 MACF1

9.50e-0582664CID000018752
DrugSC-791

KRT6B KRT6C

1.23e-046662CID010291510
Drugfenoxaprop

ID1 APP

1.72e-047662CID000086134
DrugMetaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Up 200; 7.6uM; PC3; HT_HG-U133A

HIPK3 RIPOR2 DTNA ID1 EPAS1

1.72e-041796654248_UP
Drug2-propylpentanoic acid; Up 200; 1000uM; HL60; HT_HG-U133A

MTUS1 DTNA KIF3C FNBP1L APP

2.16e-041886651150_UP
Drug2,4,5,2',5'-pentachlorobiphenyl

NWD2 LMNB1 DTNA CNTRL SYNE2 E2F7 KDR FNBP1L APP SGO1 GINS1 KIF20B STAR

2.17e-0414416613ctd:C009828
DrugAcacetin [480-44-4]; Down 200; 14uM; HL60; HT_HG-U133A

MTUS1 BTD KIF3C APP MINDY2

2.27e-041906652189_DN
Drug0317956-0000 [391210-11-0]; Down 200; 10uM; MCF7; HT_HG-U133A

HIPK3 MIA3 OMD MINDY2 EPAS1

2.27e-041906653966_DN
DrugBenfluorex hydrochloride [23642-66-2]; Down 200; 10.4uM; HL60; HT_HG-U133A

LMNB1 LONRF3 APP MINDY2 EPAS1

2.38e-041926651266_DN
DrugMeclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; PC3; HT_HG-U133A

LMNB1 MTUS1 IFT74 BTD CIR1

2.38e-041926654268_DN
DrugTranylcypromine hydrochloride [1986-47-6]; Down 200; 23.6uM; HL60; HG-U133A

LMNB1 DTNA USP46 APP PRPF39

2.44e-041936651417_DN
DrugGriseofulvin [126-07-8]; Down 200; 11.2uM; HL60; HT_HG-U133A

BTD CIR1 MACF1 GOLM1 APP

2.44e-041936652332_DN
DrugAndrosterone [53-41-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A

DOCK1 DTNA BTD CIR1 KIF3C

2.50e-041946655696_DN
Druggenistein; Up 200; 10uM; MCF7; HT_HG-U133A_EA

BTD KIF3C APP PRPF39 BBS10

2.50e-041946651073_UP
DrugCoralyne chloride hydrate [38989-38-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A

KRT2 LMNB1 DTNA CNTRL APP

2.50e-041946655418_UP
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA

BTD CNTRL MARF1 CIR1 MINDY2

2.50e-041946651001_UP
DrugLevonordefrin [829-74-3]; Down 200; 21.8uM; PC3; HT_HG-U133A

MTUS1 CIR1 RNF216 ACTN1 APP

2.50e-041946655854_DN
DrugHesperetin [520-33-2]; Down 200; 13.2uM; PC3; HG-U133A

MIA3 DTNA MACF1 KIF3C APP

2.50e-041946651947_DN
DrugSulfameter [651-06-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A

DTNA BTD MARF1 CIR1 APP

2.62e-041966653453_DN
DrugThalidomide [50-35-1]; Down 200; 15.4uM; PC3; HT_HG-U133A

DOCK1 LMNB1 IFT74 CNTRL RNF216

2.62e-041966657288_DN
DrugBetahistine mesylate [54856-23-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A

LMNB1 DTNA BTD KIF3C APP

2.62e-041966654956_DN
DrugPivmecillinam hydrochloride [32887-03-9]; Down 200; 8.4uM; PC3; HT_HG-U133A

BTD SYNE2 RNF216 PRPF39 STAR

2.62e-041966657312_DN
DrugCefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; MCF7; HT_HG-U133A

HIPK3 DTNA SCG2 CIR1 MINDY2

2.62e-041966654148_DN
DrugMethacholine chloride [62-51-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A

DTNA SIPA1L1 CNTRL KIF3C APP

2.62e-041966653452_DN
DrugN-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; HL60; HT_HG-U133A

MTUS1 IFT74 DTNA KIF3C OMD

2.62e-041966653085_DN
DrugNifenazone [2139-47-1]; Down 200; 13uM; PC3; HT_HG-U133A

DOCK1 MTUS1 BTD CNTRL APP

2.62e-041966657314_DN
DrugMometasone furoate [83919-23-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A

KRT6B LMNB1 DTNA BTD APP

2.69e-041976655541_UP
DrugPraziquantel [55268-74-1]; Up 200; 12.8uM; PC3; HT_HG-U133A

LAMB4 CNTRL CIR1 OMD EPAS1

2.69e-041976655874_UP
DrugVitexin [3681-93-4]; Down 200; 9.2uM; PC3; HT_HG-U133A

KRT6B LMNB1 CEP112 DTNA BTD

2.69e-041976654588_DN
DrugPridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; MCF7; HT_HG-U133A

DOCK1 MARF1 CIR1 ID1 ACTN1

2.69e-041976653456_DN
DrugRibavirin [36791-04-5]; Down 200; 16.4uM; MCF7; HT_HG-U133A

DOCK1 DTNA BTD SIPA1L1 CIR1

2.69e-041976656018_DN
DrugCiprofloxacin hydrochloride [93107-08-5]; Down 200; 10.8uM; HL60; HG-U133A

DTNA MACF1 USP46 LONRF3 APP

2.69e-041976652022_DN
DrugCarbinoxamine maleate salt [3505-38-2]; Up 200; 9.8uM; PC3; HT_HG-U133A

HIPK3 MTUS1 CNTRL APP MINDY2

2.69e-041976657138_UP
DrugIfosfamide [3778-73-2]; Up 200; 15.4uM; MCF7; HT_HG-U133A

SIPA1L1 CNTRL CIR1 KIF3C APP

2.69e-041976656279_UP
DrugDantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; HL60; HT_HG-U133A

DTNA BTD MACF1 USP46 APP

2.75e-041986652369_DN
DrugIobenguane sulfate; Down 200; 10.8uM; PC3; HT_HG-U133A

MTUS1 BTD RNF216 APP STAR

2.75e-041986657299_DN
DrugBenzathine benzylpenicillin [5928-84-7]; Down 200; 4.2uM; MCF7; HT_HG-U133A

DOCK1 IFT74 DTNA CIR1 MINDY2

2.75e-041986657359_DN
DrugAmrinone [60719-84-8]; Down 200; 21.4uM; HL60; HT_HG-U133A

DTNA SIPA1L1 RNF216 KIF3C OMD

2.75e-041986652724_DN
DrugRacecadotril [81110-73-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A

HIPK3 MTUS1 CNTRL KIF3C APP

2.75e-041986652774_DN
DrugCefoperazone dihydrate; Up 200; 5.8uM; MCF7; HT_HG-U133A

HIPK3 MIA3 DTNA CNTRL APP

2.75e-041986655424_UP
DrugDiflunisal [22494-42-4]; Down 200; 16uM; PC3; HG-U133A

DOCK1 DTNA SYNE2 APP KIF20B

2.75e-041986651908_DN
DrugSTOCK1N-35696; Down 200; 15uM; PC3; HT_HG-U133A

BTD ACTN1 LONRF3 APP MINDY2

2.75e-041986656564_DN
DrugNaringin hydrate [11032-30-7]; Down 200; 6.6uM; HL60; HT_HG-U133A

DTNA BTD MACF1 USP46 MINDY2

2.75e-041986652425_DN
DrugNifedipine [21829-25-4]; Down 200; 11.6uM; PC3; HT_HG-U133A

MTUS1 CEP112 BTD CNTRL STAR

2.75e-041986657303_DN
Drugclozapine; Up 200; 10uM; HL60; HT_HG-U133A

DOCK1 HIPK3 LAMB4 KRT6B SCG2

2.81e-041996656188_UP
DrugMethoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; PC3; HT_HG-U133A

LMNB1 MTUS1 DTNA BTD CNTRL

2.81e-041996656355_UP
DrugTolazoline hydrochloride [59-97-2]; Down 200; 20.4uM; PC3; HG-U133A

DOCK1 MIA3 DTNA SYNE2 APP

2.81e-041996651918_DN
DrugMoricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; MCF7; HT_HG-U133A

HIPK3 KRT2 CEP112 KDR OMD

2.81e-041996653520_UP
DrugN6,2-O-dibutyryladenosine 3,5-cyclic monophosphate sodium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA

LMNB1 MTUS1 DTNA CNTRL APP

2.81e-04199665959_DN
DrugMetanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; PC3; HG-U133A

DOCK1 KRT6B LONRF3 APP KIF20B

2.81e-041996651933_DN
DrugAzathioprine [446-86-6]; Down 200; 14.4uM; PC3; HG-U133A

DOCK1 KRT6B DTNA RNF216 KIF20B

2.81e-041996651945_DN
DrugStreptozotocin [18883-66-4]; Down 200; 15uM; PC3; HT_HG-U133A

DOCK1 BTD SYNE2 LONRF3 APP

2.81e-041996655836_DN
Drugestradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A

LAMB4 SCG2 KDR LONRF3 OMD

2.88e-042006655601_UP
DrugPiracetam [7491-74-9]; Down 200; 28.2uM; PC3; HT_HG-U133A

MTUS1 CEP112 BTD PRPF39 EPAS1

2.88e-042006655043_DN
DrugDextromethorphan hydrobromide monohydrate [6700-34-1]; Up 200; 10.8uM; HL60; HT_HG-U133A

MTUS1 TRPM3 BTD KIF3C USP46

2.88e-042006651281_UP
DiseasePR interval

MTUS1 TRPM3 DTNA SIPA1L1 SYNE2 MACF1 EPAS1

1.08e-04495657EFO_0004462
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

LMNB1 SYNE2

3.11e-0412652DOID:11726 (implicated_via_orthology)
Diseasesphingomyelin 14:0 measurement

TRPM3 SYNE2

6.36e-0417652EFO_0010390
Diseaseunipolar depression, bipolar disorder, schizophrenia, sex interaction measurement

TRPM3 E2F7 MINDY2

6.39e-0476653EFO_0003761, EFO_0008343, MONDO_0004985, MONDO_0005090
Diseaseelectrocardiography

RIPOR2 TRPM3 BTD SIPA1L1 CCDC136 EPAS1

1.10e-03530656EFO_0004327
DiseaseAdenocarcinoma of lung (disorder)

TAOK3 LMNB1 KDR GOLM1

1.12e-03206654C0152013

Protein segments in the cluster

PeptideGeneStartEntry
ANNMQEAQSIDEIYK

COPS5

16

Q92905
AEADQQMDNLYLKAL

EPAS1

81

Q99814
VEIADENNMLLDYQD

CNTRL

56

Q7Z7A1
EQQLDIMNKQYQQLE

CNTRL

561

Q7Z7A1
LAVNQENEQLMEDYE

ACTN1

266

P12814
NEYNALNEAKQMIAV

SDF4

311

Q9BRK5
LQKEQNYSDDVLANM

APP

566

P05067
FLLDEMQTAQNKYQE

GVINP1

721

Q7Z2Y8
DLLEERNKELMNEYN

ANKRD18B

596

A2A2Z9
NDYEQNMKLLQTKYD

CEP112

471

Q8N8E3
YMEEKDDEILQQNNE

CCDC42

206

Q96M95
LNMEKLENEYLDQAN

CCDC180

1081

Q9P1Z9
KDLDLNYMTQTNDQN

BBS10

426

Q8TAM1
AQKLYLQDDNDLREM

NWD2

741

Q9ULI1
QELQNLLDKYMKNSD

RFX6

546

Q8HWS3
LLDEQQVNVLLYDMN

ID1

56

P41134
NMQDLVEDLKNKYED

KRT6C

241

P48668
ETQQLLQMQQKYLEE

KMT2C

3186

Q8NEZ4
LQAKIINNNYMDTDN

MGAM2

831

Q2M2H8
AEKYKMQLQEQFDNL

MTUS1

1026

Q9ULD2
NSELNNMQDLVEDYK

KRT2

251

P35908
DQMQQQLNDYEQLLD

LMNB1

351

P20700
SALEKNMENYLQEQK

KIF3C

451

O14782
NMENYLQEQKERLEE

KIF3C

456

O14782
QLYQEAAQLDMLLEK

FLOT1

346

O75955
NMQDLVEDLKNKYED

KRT6B

241

P04259
ESIKDYEQANLNMAN

KIF20B

251

Q96Q89
EMLEQNLYDFLKQNK

HIPK3

276

Q9H422
LNLLEMEYSGDLKQN

PRPF39

531

Q86UA1
MEYSGDLKQNEENIL

PRPF39

536

Q86UA1
EKLEDAMQAAVQYQD

MACF1

6106

Q9UPN3
QEYRDEQDLNMKLVQ

CFAP53

301

Q96M91
QMRAKYLENLAQENE

HYDIN

1916

Q4G0P3
NDYNMLKAQNDRETQ

IFT74

171

Q96LB3
YEEQMAYLQQKELDL

E2F7

231

Q96AV8
NQYADMLNKKFLDQA

DOCK1

1001

Q14185
MADENKNEYAAQLQN

FNBP1L

181

Q5T0N5
QEMDKLKEQYDAELQ

CGNL1

776

Q0VF96
EALELMNQNLDIYEQ

BTD

81

P43251
DYQLKAVVQMENLQD

MARF1

831

Q9Y4F3
NQAFNEDNLKFILMD

LAMTOR2

61

Q9Y2Q5
RQLENELQMEEYLKQ

DTNA

716

Q9Y4J8
QNSLEYMDQNDDRLK

HEPACAM

276

Q14CZ8
MQLNEQLKAVYEFQD

LAMB4

1256

A4D0S4
NQQKLRGEDDYNMDE

GOLM1

341

Q8NBJ4
QQQQAEYEDLMGQKD

GRIPAP1

371

Q4V328
EYEDLMGQKDDLNSQ

GRIPAP1

376

Q4V328
NLEHLYLQNNEIEKM

OMD

301

Q99983
KGQQDQIDQDYLMAL

MINDY2

506

Q8NBR6
QNQYKKQMLDDIPED

SPATA22

206

Q8NHS9
NAEENDKLYKVLQNM

SYNE2

3126

Q8WXH0
EILNELYQQKEMALQ

MIA3

1521

Q5JRA6
ENMKYGEQLLSDQLL

NEXMIF

191

Q5QGS0
QMAYENLNDKDQELG

SCG2

491

P13521
NYQDNNKMLVLALEN

SGO1

56

Q5FBB7
TEQLMKLDEQGLNYQ

SIPA1L1

596

O43166
QLQQEMELLNAYQSK

TAOK3

801

Q9H2K8
LLALQMNEEQYQKDG

RNF216

496

Q9NWF9
QYKEFQDLNQEVMNL

RIPOR2

621

Q9Y4F9
MYDAGQAKQELLQQE

CCDC136

691

Q96JN2
ELMQQYLKEQESYDN

CIR1

41

Q86X95
IKYSMDDQLNQLFNL

ERVK-25

531

P63136
QELAYLQQGEEAMQK

STAR

71

P49675
ELLDQSYKQDEQLAM

TRPM3

731

Q9HCF6
GELLNQVQMAKLYQD

TREH

36

O43280
RKENELFDNYMQQDA

USP12

111

O75317
AMNEYNKALEIDKQN

TTC14

326

Q96N46
LRKENDLFDNYMQQD

USP46

106

P62068
IMELKNASLQDQGDY

KDR

626

P35968
IKYSMDDQLNQLFNL

ERVK-19

536

Q9WJR5
MKALYEQNQSDVNEA

GINS1

36

Q14691
DKAQINLYQDVMLEN

ZNF285

26

Q96NJ3
LYEEEMEELSNLNKN

LONRF3

541

Q496Y0