Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

SREBF2 ADNP2 JUNB FOXK2 CREB3L3 ZHX2 FOXP2 MEF2A MEF2C GLI3 ZNF652

1.18e-0414124211GO:0000981
GeneOntologyMolecularFunctionchromatin binding

SREBF2 TPR BRD3 MEF2A HCFC1 MEF2C GLI3 SBNO2

1.31e-04739428GO:0003682
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

SREBF2 JUNB FOXK2 CREB3L3 FOXP2 MEF2A HCFC1 MEF2C GLI3 ZNF652

2.00e-0412444210GO:0000978
GeneOntologyMolecularFunctionstructural constituent of postsynaptic density

SHANK1 CTNND2

2.35e-0411422GO:0098919
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

SREBF2 JUNB FOXK2 CREB3L3 FOXP2 MEF2A HCFC1 MEF2C GLI3 ZNF652

2.38e-0412714210GO:0000987
GeneOntologyMolecularFunctionstructural constituent of postsynaptic specialization

SHANK1 CTNND2

3.32e-0413422GO:0098879
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

SREBF2 JUNB FOXK2 CREB3L3 FOXP2 MEF2A HCFC1 MEF2C GLI3 ZNF652

7.13e-0414594210GO:0000977
GeneOntologyMolecularFunctionprotein dimerization activity

SREBF2 TPR CREB3L3 TAF4B SH3GLB1 ZHX2 FOXP2 MEF2A MEF2C

7.52e-041205429GO:0046983
GeneOntologyMolecularFunctionprotein heterodimerization activity

CREB3L3 TAF4B ZHX2 MEF2A MEF2C

1.42e-03398425GO:0046982
GeneOntologyMolecularFunctionhistone acetyltransferase binding

MEF2A GLI3

1.69e-0329422GO:0035035
GeneOntologyMolecularFunctionstructural constituent of postsynapse

SHANK1 CTNND2

2.06e-0332422GO:0099186
GeneOntologyMolecularFunctionfibronectin binding

SSC5D LPA

2.89e-0338422GO:0001968
GeneOntologyMolecularFunctionstructural constituent of synapse

SHANK1 CTNND2

3.53e-0342422GO:0098918
GeneOntologyMolecularFunctionhistone deacetylase binding

MEF2A MEF2C GLI3

3.64e-03147423GO:0042826
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

SHANK1 ROBO2 SH3GLB1 CTNND2 MAP1S MEGF9 RAPH1 MEF2A MEF2C GLI3

2.40e-067484310GO:0048667
GeneOntologyBiologicalProcessneuron projection morphogenesis

SHANK1 ROBO2 SH3GLB1 CTNND2 MAP1S MEGF9 RAPH1 MEF2A MEF2C GLI3

4.46e-068024310GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

SHANK1 ROBO2 SH3GLB1 CTNND2 MAP1S MEGF9 RAPH1 MEF2A MEF2C GLI3

5.37e-068194310GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

SHANK1 ROBO2 SH3GLB1 CTNND2 MAP1S MEGF9 RAPH1 MEF2A MEF2C GLI3

5.79e-068264310GO:0048858
GeneOntologyBiologicalProcessvocalization behavior

SHANK1 FOXP2 GLI3

1.66e-0524433GO:0071625
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

SREBF2 JUNB BRD3 FOXK2 CREB3L3 TAF4B EAF2 MEF2A HCFC1 MEF2C GLI3 SBNO2

1.81e-0513904312GO:0045944
GeneOntologyBiologicalProcesscell morphogenesis

SHANK1 ROBO2 SH3GLB1 CTNND2 MAP1S MEGF9 RAPH1 PRPF40A MEF2A MEF2C GLI3

2.41e-0511944311GO:0000902
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

SREBF2 TPR FOXK2 MAGEE1 ZHX2 FOXP2 MEF2A HCFC1 MEF2C GLI3

4.73e-0510534310GO:0000122
GeneOntologyBiologicalProcessdendrite development

SHANK1 SH3GLB1 CTNND2 MAP1S MEF2A MEF2C

6.45e-05335436GO:0016358
GeneOntologyBiologicalProcessspecification of animal organ identity

ROBO2 MEF2C GLI3

8.51e-0541433GO:0010092
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

SREBF2 TPR FOXK2 MAGEE1 ZHX2 FOXP2 MEF2A HCFC1 MEF2C GLI3 SBNO2

1.02e-0413994311GO:0045892
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

SREBF2 TPR FOXK2 MAGEE1 ZHX2 FOXP2 MEF2A HCFC1 MEF2C GLI3 SBNO2

1.12e-0414134311GO:1902679
GeneOntologyBiologicalProcessneuron development

SHANK1 ROBO2 SH3GLB1 CTNND2 MAP1S MEGF9 RAPH1 MEF2A MEF2C HCN1 GLI3

1.53e-0414634311GO:0048666
GeneOntologyBiologicalProcessneuron projection development

SHANK1 ROBO2 SH3GLB1 CTNND2 MAP1S MEGF9 RAPH1 MEF2A MEF2C GLI3

2.46e-0412854310GO:0031175
GeneOntologyBiologicalProcessrighting reflex

SHANK1 FOXP2

2.77e-0412432GO:0060013
GeneOntologyBiologicalProcessresponse to calcium ion

JUNB MEF2A MEF2C HCN1

3.48e-04161434GO:0051592
GeneOntologyCellularComponentextracellular matrix

SERPING1 SSC5D PCOLCE2 MEGF9 CD248 MUC17 HCFC1 LPA

4.95e-05656438GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

SERPING1 SSC5D PCOLCE2 MEGF9 CD248 MUC17 HCFC1 LPA

5.05e-05658438GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

SERPING1 SSC5D PCOLCE2 MEGF9 MUC17 HCFC1 LPA

9.45e-05530437GO:0062023
GeneOntologyCellularComponentchromatin

SREBF2 ADNP2 JUNB BRD3 FOXK2 CREB3L3 ZHX2 FOXP2 MEF2A HCFC1 MEF2C

1.50e-0414804311GO:0000785
DomainHJURP_C

MEF2A MEF2C

2.95e-054422IPR022102
DomainHJURP_C

MEF2A MEF2C

2.95e-054422PF12347
DomainMADS_MEF2-like

MEF2A MEF2C

2.95e-054422IPR033896
DomainMADS

MEF2A MEF2C

7.36e-056422SM00432
DomainMADS_BOX_1

MEF2A MEF2C

7.36e-056422PS00350
DomainSRF-TF

MEF2A MEF2C

7.36e-056422PF00319
DomainMADS_BOX_2

MEF2A MEF2C

7.36e-056422PS50066
DomainTF_MADSbox

MEF2A MEF2C

1.03e-047422IPR002100
DomainSEA

MUC16 MUC17

4.42e-0414422SM00200
Domain-

MUC16 MUC17

5.09e-04154223.30.70.960
DomainRmlC_Cupin

FOXP2 MPI

5.81e-0416422IPR011051
DomainSEA

MUC16 MUC17

1.11e-0322422PF01390
DomainSEA

MUC16 MUC17

1.21e-0323422PS50024
DomainSEA_dom

MUC16 MUC17

1.21e-0323422IPR000082
DomainbZIP_1

JUNB CREB3L3

2.65e-0334422PF00170
DomainTF_DNA-bd

JUNB CREB3L3

3.13e-0337422IPR008917
DomainTF_fork_head_CS_2

FOXK2 FOXP2

4.80e-0346422IPR030456
DomainTF_fork_head_CS_1

FOXK2 FOXP2

5.01e-0347422IPR018122
Domain-

HCN1 MPI

5.22e-03484222.60.120.10
DomainFORK_HEAD_3

FOXK2 FOXP2

5.43e-0349422PS50039
DomainFH

FOXK2 FOXP2

5.43e-0349422SM00339
DomainFORK_HEAD_1

FOXK2 FOXP2

5.43e-0349422PS00657
DomainFORK_HEAD_2

FOXK2 FOXP2

5.43e-0349422PS00658
DomainForkhead

FOXK2 FOXP2

5.43e-0349422PF00250
DomainFork_head_dom

FOXK2 FOXP2

5.43e-0349422IPR001766
DomainWW_DOMAIN_2

ARHGAP9 PRPF40A

5.87e-0351422PS50020
DomainRmlC-like_jellyroll

HCN1 MPI

5.87e-0351422IPR014710
DomainWW_DOMAIN_1

ARHGAP9 PRPF40A

5.87e-0351422PS01159
DomainWW_dom

ARHGAP9 PRPF40A

6.10e-0352422IPR001202
DomainBRLZ

JUNB CREB3L3

6.10e-0352422SM00338
DomainBZIP

JUNB CREB3L3

6.33e-0353422PS50217
DomainBZIP_BASIC

JUNB CREB3L3

6.33e-0353422PS00036
DomainbZIP

JUNB CREB3L3

6.56e-0354422IPR004827
DomainSH3

SHANK1 ARHGAP9 SH3GLB1

1.26e-02216423PS50002
DomainSH3

SHANK1 ARHGAP9 SH3GLB1

1.26e-02216423SM00326
DomainSH3_domain

SHANK1 ARHGAP9 SH3GLB1

1.32e-02220423IPR001452
Pubmed

A census of human transcription factors: function, expression and evolution.

SREBF2 ADNP2 JUNB FOXK2 CREB3L3 ZHX2 FOXP2 MEF2A MEF2C GLI3

1.23e-07908431019274049
Pubmed

Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice.

MEF2A MEF2C

1.49e-06243216469744
Pubmed

Restoration of impaired endothelial myocyte enhancer factor 2 function rescues pulmonary arterial hypertension.

MEF2A MEF2C

1.49e-06243225336633
Pubmed

Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c.

FOXP2 MEF2C

1.49e-06243227595386
Pubmed

Regulation of myocyte enhancer factor-2 transcription factors by neurotoxins.

MEF2A MEF2C

1.49e-06243221741404
Pubmed

Overexpression of myocyte enhancer factor 2 and histone hyperacetylation in hepatocellular carcinoma.

MEF2A MEF2C

1.49e-06243217611778
Pubmed

Histone methyltransferase MLL4 controls myofiber identity and muscle performance through MEF2 interaction.

KMT2B MEF2A

4.48e-06343232544095
Pubmed

The nuclear localization domain of the MEF2 family of transcription factors shows member-specific features and mediates the nuclear import of histone deacetylase 4.

MEF2A MEF2C

4.48e-06343211792813
Pubmed

Mef2 promotes spine elimination in absence of δ-catenin.

CTNND2 MEF2C

4.48e-06343223328440
Pubmed

An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133.

MEF2A MEF2C

4.48e-06343218093911
Pubmed

MEF2 is a converging hub for histone deacetylase 4 and phosphatidylinositol 3-kinase/Akt-induced transformation.

MEF2A MEF2C

4.48e-06343224043307
Pubmed

Alternative pre-mRNA splicing governs expression of a conserved acidic transactivation domain in myocyte enhancer factor 2 factors of striated muscle and brain.

MEF2A MEF2C

4.48e-06343215834131
Pubmed

In vivo analysis of MEF2 transcription factors in synapse regulation and neuronal survival.

MEF2A MEF2C

4.48e-06343222496871
Pubmed

Inducible knockout of Mef2a, -c, and -d from nestin-expressing stem/progenitor cells and their progeny unexpectedly uncouples neurogenesis and dendritogenesis in vivo.

MEF2A MEF2C

4.48e-06343226286136
Pubmed

MEF2 transcription factors differentially contribute to retinal ganglion cell loss after optic nerve injury.

MEF2A MEF2C

4.48e-06343233315889
Pubmed

Experience-Dependent and Differential Regulation of Local and Long-Range Excitatory Neocortical Circuits by Postsynaptic Mef2c.

MEF2A MEF2C

4.48e-06343227989458
Pubmed

Temporal analysis of enhancers during mouse cerebellar development reveals dynamic and novel regulatory functions.

ROBO2 FOXP2 HCN1

5.64e-062843335942939
Pubmed

High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization.

ADNP2 FOXK2 KMT2B HCFC1

5.70e-069443416325481
Pubmed

Human transcription factor protein interaction networks.

JUNB FOXK2 KMT2B ZHX2 FOXP2 PRPF40A MEF2A HCFC1 MEF2C GLI3

7.37e-061429431035140242
Pubmed

Vgl-4, a novel member of the vestigial-like family of transcription cofactors, regulates alpha1-adrenergic activation of gene expression in cardiac myocytes.

MEF2A MEF2C

8.94e-06443215140898
Pubmed

Neurotoxin-induced selective ubiquitination and regulation of MEF2A isoform in neuronal stress response.

MEF2A MEF2C

8.94e-06443222764880
Pubmed

Regional chromosomal assignments for four members of the MADS domain transcription enhancer factor 2 (MEF2) gene family to human chromosomes 15q26, 19p12, 5q14, and 1q12-q23.

MEF2A MEF2C

8.94e-0644328575763
Pubmed

Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors.

MEF2A MEF2C

8.94e-06443210330143
Pubmed

MEF2 transcription factors regulate distinct gene programs in mammalian skeletal muscle differentiation.

MEF2A MEF2C

8.94e-06443225416778
Pubmed

Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene.

MEF2A MEF2C

8.94e-06443210207130
Pubmed

Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins.

MEF2A MEF2C

8.94e-0644328548800
Pubmed

Spine growth in the anterior cingulate cortex is necessary for the consolidation of contextual fear memory.

MEF2A MEF2C

8.94e-06443221531906
Pubmed

Requirement of MEF2A, C, and D for skeletal muscle regeneration.

MEF2A MEF2C

8.94e-06443224591619
Pubmed

Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation.

MEF2A MEF2C

8.94e-0644327643214
Pubmed

TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters.

MEF2A MEF2C

8.94e-06443212061776
Pubmed

Neuronal Myocyte-Specific Enhancer Factor 2D (MEF2D) Is Required for Normal Circadian and Sleep Behavior in Mice.

MEF2A MEF2C

8.94e-06443231420455
Pubmed

Early expression of the different isoforms of the myocyte enhancer factor-2 (MEF2) protein in myogenic as well as non-myogenic cell lineages during mouse embryogenesis.

MEF2A MEF2C

8.94e-0644328817457
Pubmed

Dermo-1, a multifunctional basic helix-loop-helix protein, represses MyoD transactivation via the HLH domain, MEF2 interaction, and chromatin deacetylation.

MEF2A MEF2C

8.94e-06443211809751
Pubmed

Galpha13 regulates MEF2-dependent gene transcription in endothelial cells: role in angiogenesis.

MEF2A MEF2C

1.49e-05543219093215
Pubmed

Calcineurin initiates skeletal muscle differentiation by activating MEF2 and MyoD.

MEF2A MEF2C

1.49e-05543212694204
Pubmed

Expression of MEF2 genes during human cardiac development.

MEF2A MEF2C

1.49e-05543210458488
Pubmed

Control of the SOST bone enhancer by PTH using MEF2 transcription factors.

MEF2A MEF2C

1.49e-05543217696759
Pubmed

Membrane hyperpolarization triggers myogenin and myocyte enhancer factor-2 expression during human myoblast differentiation.

MEF2A MEF2C

1.49e-05543215084602
Pubmed

The MEF2B homologue differentially expressed in mouse embryonal carcinoma cells.

MEF2A MEF2C

1.49e-0554327646512
Pubmed

HDAC4 integrates PTH and sympathetic signaling in osteoblasts.

MEF2A MEF2C

1.49e-05543224934156
Pubmed

Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1.

MEF2A MEF2C

1.49e-0554329753748
Pubmed

Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors.

MEF2A MEF2C

1.49e-05543220833138
Pubmed

Absence of MEF2 binding to the A/T-rich element in the muscle creatine kinase (MCK) enhancer correlates with lack of early expression of the MCK gene in embryonic mammalian muscle.

MEF2A MEF2C

1.49e-0554328993831
Pubmed

Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity.

MEF2A MEF2C

1.49e-05543223511190
Pubmed

Regulatory role of MEF2D in serum induction of the c-jun promoter.

MEF2A MEF2C

1.49e-0554327760790
Pubmed

Cooperative transcriptional activation by the neurogenic basic helix-loop-helix protein MASH1 and members of the myocyte enhancer factor-2 (MEF2) family.

MEF2A MEF2C

1.49e-0554328900141
Pubmed

Regulation of the MEF2 family of transcription factors by p38.

MEF2A MEF2C

1.49e-0554329858528
Pubmed

Cooperation between MEF2 and PPARgamma in human intestinal beta,beta-carotene 15,15'-monooxygenase gene expression.

MEF2A MEF2C

1.49e-05543216504037
Pubmed

MEF2 transcription factors are key regulators of sprouting angiogenesis.

MEF2A MEF2C

1.49e-05543227898394
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

SH3GLB1 CTNND2 MEF2A MEF2C

1.93e-0512843430995482
Pubmed

Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases.

MEF2A MEF2C

2.23e-05643210737771
Pubmed

The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2.

MEF2A MEF2C

2.23e-05643222135324
Pubmed

Akt binds prohibitin 2 and relieves its repression of MyoD and muscle differentiation.

MEF2A MEF2C

2.23e-05643215173318
Pubmed

TRIM72, a novel negative feedback regulator of myogenesis, is transcriptionally activated by the synergism of MyoD (or myogenin) and MEF2.

MEF2A MEF2C

2.23e-05643220399744
Pubmed

The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex.

FOXK2 HCFC1

2.23e-05643224748658
Pubmed

The expression of MEF2 genes is implicated in CNS neuronal differentiation.

MEF2A MEF2C

2.23e-0564329013788
Pubmed

Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteins.

MEF2A MEF2C

2.23e-05643211160896
Pubmed

BRCA1-associated protein 1 (BAP1) deubiquitinase antagonizes the ubiquitin-mediated activation of FoxK2 target genes.

FOXK2 HCFC1

2.23e-05643225451922
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

SREBF2 BRD3 FOXK2 FOXP2 MEF2A MEF2C GLI3

2.42e-0570943722988430
Pubmed

Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays.

ROBO2 FOXP2 MEF2C

2.75e-054743335512705
Pubmed

Multiple roles for the MyoD basic region in transmission of transcriptional activation signals and interaction with MEF2.

MEF2A MEF2C

3.12e-0574329418854
Pubmed

Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis.

MEF2A MEF2C

3.12e-0574328026334
Pubmed

Transcription enhancer factor 1 binds multiple muscle MEF2 and A/T-rich elements during fast-to-slow skeletal muscle fiber type transitions.

MEF2A MEF2C

3.12e-05743212861002
Pubmed

Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation.

MEF2A MEF2C

3.12e-05743211081517
Pubmed

Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers.

MEF2A MEF2C

4.16e-05843217786239
Pubmed

MEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promoters.

MEF2A MEF2C

4.16e-05843216043483
Pubmed

MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis.

MEF2A MEF2C

4.16e-05843230205047
Pubmed

Quantitative Trait Loci and a Novel Genetic Candidate for Fear Learning.

MEF2C HCN1

4.16e-05843227277803
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TPR JUNB BRD3 KMT2B MAP1S RAPH1 PRPF40A

4.22e-0577443715302935
Pubmed

The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.

FOXK2 HCFC1

5.35e-05943226416890
Pubmed

Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes.

MEF2A MEF2C

5.35e-0594328530078
Pubmed

Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo.

MEF2A MEF2C

5.35e-0594329738004
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

SERPING1 PCOLCE2 HCFC1 LPA

5.47e-0516743422159717
Pubmed

A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.

RAPH1 MEF2A MEF2C

5.73e-056043319075228
Pubmed

Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS.

KMT2B HCFC1

6.68e-051043218838538
Pubmed

ASXL3 bridges BRD4 to BAP1 complex and governs enhancer activity in small cell lung cancer.

FOXK2 HCFC1

6.68e-051043232669118
Pubmed

Myocyte Enhancer Factor 2c Regulates Dendritic Complexity and Connectivity of Cerebellar Purkinje Cells.

MEF2A MEF2C

6.68e-051043230276662
Pubmed

The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.

FOXK2 HCFC1

6.68e-051043219815555
Pubmed

FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands.

KMT2B PRPF40A

6.68e-05104329171351
Pubmed

A novel pro-Arg motif recognized by WW domains.

KMT2B PRPF40A

6.68e-051043210744724
Pubmed

Bioinformatics and cellular signaling.

SREBF2 ZHX2 PRPF40A MEF2C

7.63e-0518243415102471
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

TPR JUNB FOXK2 FOXP2 MEF2A HCFC1 MEF2C

8.01e-0585743725609649
Pubmed

Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C.

MEF2A MEF2C

8.15e-05114329162005
Pubmed

Gli3 Regulates Vomeronasal Neurogenesis, Olfactory Ensheathing Cell Formation, and GnRH-1 Neuronal Migration.

ROBO2 GLI3

9.78e-051243231767679
Pubmed

Developmental origin of the neuronal subtypes that comprise the amygdalar fear circuit in the mouse.

FOXP2 MEF2C

9.78e-051243220484636
Pubmed

Satb2 Regulates the Differentiation of Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex.

FOXP2 HCN1

9.78e-051243225037921
Pubmed

Arrhythmia induced by spatiotemporal overexpression of calreticulin in the heart.

MEF2C HCN1

9.78e-051243217482496
Pubmed

Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.

KMT2B HCFC1

9.78e-051243227563068
Pubmed

Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.

MEF2A MEF2C

9.78e-051243228641113
Pubmed

Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1.

MEF2A MEF2C

9.78e-051243216424906
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

ROBO2 CREB3L3 MAGEE1 KMT2B ZHX2 PRPF40A

9.80e-0560843616713569
Pubmed

Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (Jarid2)-cyclin D1 pathway.

MEF2A MEF2C

1.15e-041343221447557
Pubmed

Zbtb20 defines a hippocampal neuronal identity through direct repression of genes that control projection neuron development in the isocortex.

FOXP2 MEF2C

1.15e-041343223283686
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

TPR FOXK2 ZHX2 PRPF40A HCFC1

1.30e-0439943535987950
Pubmed

A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.

SREBF2 HCFC1

1.35e-041443210976766
Pubmed

Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation.

MEF2A MEF2C

1.35e-041443212130539
Pubmed

Identification of the ankyrin repeat proteins ANKRA and RFXANK as novel partners of class IIa histone deacetylases.

MAP1S MEF2C

1.35e-041443215964851
Pubmed

Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains.

KMT2B PRPF40A

1.35e-04144328605874
Pubmed

A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing.

MEF2A MEF2C

1.35e-04144328114702
Pubmed

O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.

CTNND2 HCFC1

1.35e-041443216452088
CytobandEnsembl 112 genes in cytogenetic band chr19p13

MUC16 JUNB CREB3L3 MAP1S SBNO2

8.68e-04797435chr19p13
GeneFamilyMyocyte enhancer factor 2 proteins|MADS box family

MEF2A MEF2C

1.70e-054312649
GeneFamilyMyocyte enhancer factor 2 proteins|MADS box family

MEF2A MEF2C

2.84e-0553121086
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ADNP2 ZHX2

2.95e-0415312529
GeneFamilyCD molecules|Mucins

MUC16 MUC17

5.85e-0421312648
GeneFamilyForkhead boxes

FOXK2 FOXP2

2.46e-0343312508
GeneFamilyBasic leucine zipper proteins

JUNB CREB3L3

3.18e-0349312506
CoexpressionMARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN

TPR SH3GLB1 PRPF40A MEF2A HCFC1 GLI3 LPA

2.27e-05543427MM997
CoexpressionTURJANSKI_MAPK11_TARGETS

MEF2A MEF2C

2.50e-055422M2492
CoexpressionBOYAULT_LIVER_CANCER_SUBCLASS_G1_UP

SREBF2 TPR BRD3 CTNND2

3.58e-05116424M14146
CoexpressionTURJANSKI_MAPK7_TARGETS

MEF2A MEF2C

5.24e-057422M11218
ToppCellnormal-na-Lymphocytic_B-B_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

MUC16 MAGEE1 EAF2 MEF2A MEF2C

4.35e-07162425ae292318d339305932457bb0e91430594f7a3dfa
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248 GLI3

8.15e-071844253bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCelldroplet-Kidney-nan-21m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248 GLI3

8.37e-0718542533cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248 GLI3

8.37e-071854259954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERPING1 SSC5D PCOLCE2 CD248 GLI3

9.06e-07188425aa516273cdde53c8c0295f06830972388f890c97
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 FOXP2 CD248

9.55e-07190425f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCelldroplet-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 FOXP2 CD248

9.55e-071904252abeb013bb83c578e67dcb985ba44ca63134950b
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 FOXP2 CD248

9.80e-07191425d1205aab0937f2becfcd239610e9b78fb8a0c886
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 FOXP2 CD248

1.03e-061934250a665531d581d4e3941e29d3f95569da8f166447
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 FOXP2 CD248

1.03e-0619342524ce1f37cca655415410d2403a52d1ebb3332280
ToppCell10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SERPING1 ROBO2 PCOLCE2 FOXP2 GLI3

1.08e-0619542530ed961151b8b1f6ce37f06c9a061519f01c2864
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

ROBO2 CTNND2 DNAH8 HCN1

1.51e-051594245335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO2 RAPH1 CD248 MEF2C

1.59e-051614241b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

1.92e-05169424bb43abad2c049b7f4d307737347290e01b3339a3
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

1.92e-051694245f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

1.92e-051694248bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO2 RAPH1 CD248 MEF2C

2.06e-0517242408a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO2 RAPH1 CD248 MEF2C

2.06e-05172424553701349444eb366df3c11f54bb093434f153c6
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SREBF2 EAF2 MEF2A MEF2C

2.11e-05173424f135cc9dcf34f33ced3210171ab40ae6d77cfae0
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SREBF2 EAF2 MEF2A MEF2C

2.11e-0517342423248019c819f6e38337dcc4edb763ef1992e89e
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SERPING1 PCOLCE2 ZHX2 CD248

2.26e-0517642408f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCellfacs-Kidney-nan-24m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

2.46e-05180424f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-FCRL4+_Memory_B|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC16 DNAH8 MEF2A MEF2C

2.46e-05180424eedb6d89680f968167afb1dcd132c9de9096b50f
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Dendritic_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 PCOLCE2 CTNND2 GLI3

2.46e-051804245b7d2336ed09d07f6b8dd91c1fa9c5ade633c104
ToppCellfacs-Kidney-nan-24m-Mesenchymal-kidney_interstitial_fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

2.52e-05181424c7f5aedcb74c21fb587a95a16d700e2a38a380ee
ToppCellfacs-Kidney-nan-24m-Mesenchymal-kidney_interstitial_fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

2.52e-051814240ec9621a078d004bbd25a587757d24b5cf162959
ToppCellMesenchymal_cells-Osteoblasts|Mesenchymal_cells / Lineage and Cell class

ROBO2 CREB3L3 MEF2C ZNF652

2.63e-05183424d6b52d52fe9a7a6c798947f05420d79fe12e4662
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 PCOLCE2 CD248 MEF2C

2.68e-05184424fea4fe648e9749177d0783443dc26a7df5807883
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR JUNB MEF2A MEF2C

2.68e-051844241154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 PCOLCE2 CD248 MEF2C

2.68e-0518442496a8a0a190bc293655fe7d80cbed8119c0da25f2
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 PCOLCE2 CD248 MEF2C

2.68e-05184424780eb72da43527f0c72effac3423ec7384f05f20
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

2.74e-051854243cd0686a14e734a0f243070ab939adcb4c454478
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SREBF2 EAF2 DNAH8 MEF2C

2.74e-051854243563dd39ec58d3273f95f5bb36b9ccdc0aafb63a
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

2.74e-0518542400258f458cbf6d36449db95528a6b5038d731d2d
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

2.74e-05185424a94694e226856bc5b168464f52d76004145717a5
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SHANK1 FOXP2 CD248 GLI3

2.74e-051854241b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCellCOPD-Lymphoid-B|COPD / Disease state, Lineage and Cell class

SREBF2 TAF4B ZHX2 MEF2C

2.74e-05185424925e79c35c381dd44ec5fb921dca09ce43140135
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERPING1 SSC5D PCOLCE2 CD248

2.74e-05185424d5f5866924648a3c14e2596218fd548a31777aa3
ToppCellCOPD-Lymphoid-B|World / Disease state, Lineage and Cell class

SREBF2 TAF4B ZHX2 MEF2C

2.74e-0518542422891ed75e25ef30dfa541cb82d85e08ce07e7d9
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC16 MEGF9 DNAH8 HCN1

2.80e-0518642423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERPING1 PCOLCE2 CD248 GLI3

2.80e-051864247c1807fca590cdccf7f5734460bac228d33964ca
ToppCellHealthy_donor-B_memory|World / disease group, cell group and cell class (v2)

MUC16 EAF2 DNAH8 MEF2C

2.86e-051874244f68e3243071a4549c80aff8bff32c6ad892ee7f
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EAF2 DNAH8 MEF2A MEF2C

2.98e-051894242b53dae0e6e85b7139f8a9872fbebb3705b2f1bf
ToppCellHealthy_donor-B_memory|Healthy_donor / disease group, cell group and cell class (v2)

MUC16 EAF2 DNAH8 MEF2C

3.04e-0519042446104a521f00d399315deca86699cb261b2795d6
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

3.10e-051914241b26056df078674f37a6c06f6256b30cfcec21a7
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

3.17e-051924245e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCellPND07|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ROBO2 JUNB PCOLCE2 CD248

3.17e-051924248171a60df481195c39a7f740effcae8e4deb6ca7
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

3.17e-051924242d9e2262f1342fe17735f21f733c029d1275e955
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

3.17e-05192424136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCellmoderate-Lymphoid-B_cell|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

EAF2 DNAH8 MEF2A MEF2C

3.17e-05192424ae3727503c3b9f4695e565fd3161cc33b898f349
ToppCellPND28-Mesenchymal-Mesenchymal_structural|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SERPING1 ROBO2 PCOLCE2 CD248

3.23e-05193424ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

3.23e-051934241afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

3.23e-0519342449600db68ed65cafc67bd45a285b364e4f5f88af
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

3.23e-05193424428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

3.23e-05193424eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

SREBF2 DNAH8 MEF2A MEF2C

3.23e-051934247ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCelldroplet-Fat-Scat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

3.23e-051934248dc6db335678f3a5cfd36026ad811fed8d9cb4bc
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SERPING1 ROBO2 PCOLCE2 CD248

3.23e-0519342430481fb01c7acf85beae10213f038da86bed6777
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SSC5D PCOLCE2 CD248

3.23e-0519342445b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 JUNB MEF2A MEF2C

3.30e-051944242224c7c943cfd5c1a329dfcf19d6e5ef8c49d85d
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 JUNB MEF2A MEF2C

3.30e-0519442450c5fc349533281a426bc7227a8ea9eca8d11985
ToppCellsevere-B_cell|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

EAF2 DNAH8 MEF2C MPI

3.30e-051944242fee6083fb56b16d1f04fd0b92ec622fd26ba3fa
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EAF2 DNAH8 MEF2C HCN1

3.30e-0519442440c7f9bd69a8e843b81972e25a67f591021415dd
ToppCellfacs-Brain_Myeloid-Cortex-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 JUNB MEF2A MEF2C

3.30e-051944241662b110f84584e75150df0ac970e7df82f26e7e
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 JUNB MEF2A MEF2C

3.30e-05194424b31d6361fa939a92a4a3dc63c209ecd3eb514e6a
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EAF2 DNAH8 MEF2C HCN1

3.37e-0519542451e6cfecd66a874673d0b79a295489a358bddfd5
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 SCAMP2 MEF2A MEF2C

3.37e-05195424a1478021a3ed0e779716393124ca2a7770c433b7
ToppCellsevere-B_cell|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

EAF2 DNAH8 MEF2C MPI

3.37e-051954240fc3c605609c9e6bdea15d73c45def2188ae5fb1
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ROBO2 FOXP2 CD248 GLI3

3.43e-05196424cbfe01ba8071864e19b37028236ae35789f630fe
ToppCellPND10-Mesenchymal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SERPING1 ROBO2 PCOLCE2 CD248

3.43e-05196424ace167a40adb7022b365be3c2b1cbd4ba963739a
ToppCellPND07-Mesenchymal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SERPING1 ROBO2 PCOLCE2 CD248

3.43e-051964240050c7134473fbfd7b9f0ae8d6d337713e60b57d
ToppCell368C|World / Donor, Lineage, Cell class and subclass (all cells)

SERPING1 JUNB PCOLCE2 CD248

3.50e-05197424f41211923938e5d7bfe6bf24f604ab386f17ef10
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SERPING1 ROBO2 CD248 GLI3

3.50e-05197424c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCellPND14-Mesenchymal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SERPING1 ROBO2 PCOLCE2 CD248

3.50e-051974249a14bc2e7d6081e2ab0e2e5555fc8804f13d3dbe
ToppCelldroplet-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Scara5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPING1 JUNB PCOLCE2 CD248

3.57e-05198424d4f74320ea6c1a7e568ee5bc48bb66cb45e1004d
ToppCellCOVID-19_Severe-Neu_1|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients

SERPING1 JUNB SH3GLB1 SBNO2

3.57e-05198424bbe639ea5a636c985e509fb0a133ae3b60afac5a
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SERPING1 ROBO2 PCOLCE2 CD248

3.57e-051984246a539d3b47bd2d4a7ad5c67cad23facffc0ac45f
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ROBO2 JUNB FOXP2 GLI3

3.57e-05198424a883e25cb7a78b2ecfb15cef4633bdd02dfafb12
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPING1 JUNB CD248 GLI3

3.57e-05198424c66097ae9ba0b50561083c423565665958ef0bb8
ToppCellFibroblasts-HLA-DRA_high_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SERPING1 SSC5D CD248 GLI3

3.57e-05198424e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCellE18.5-Mesenchymal|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SERPING1 ROBO2 PCOLCE2 CD248

3.57e-05198424a16aa41eab2e297e56de43c22c355df0f79315da
ToppCellFibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SERPING1 SSC5D CD248 GLI3

3.64e-0519942440de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Transverse / Region, Cell class and subclass

SERPING1 SSC5D TIMD4 RAPH1

3.64e-05199424facf79c256db5ae57bdb613e86ec90616a6f67ca
ToppCellTransverse-(6)_Macrophage-(61)_LYVE1_Macrophage|Transverse / shred on region, Cell_type, and subtype

SERPING1 SSC5D TIMD4 RAPH1

3.64e-05199424dcc2a7f4d1fa30aaaad655dd59c5a2b039d264bf
ToppCellwk_20-22-Mesenchymal-Fibroblast-Adventitial_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SERPING1 SSC5D PCOLCE2 CD248

3.64e-05199424ab0589c068c24aa989bdca083504fbad0c15221d
ToppCellCOVID-19_Severe-Neu_1|World / 5 Neutrophil clusters in COVID-19 patients

SERPING1 JUNB SH3GLB1 SBNO2

3.64e-05199424e4d8bf016fd95a440e30014a75587e097e90cfad
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SERPING1 ROBO2 PCOLCE2 GLI3

3.72e-0520042416a7c398626b6e82b394eb3ef013bda3a788659d
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SERPING1 ROBO2 PCOLCE2 GLI3

3.72e-05200424780d47f8eff630020dfae32218de495a7e9dbad6
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SERPING1 ROBO2 PCOLCE2 GLI3

3.72e-0520042428dd127787a57276253548d1f030814b1af64481
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SERPING1 SSC5D PCOLCE2 CD248

3.72e-052004246f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SERPING1 SSC5D PCOLCE2 CD248

3.72e-052004243a164e3971bcd62b148b813171c103adb81f972e
ToppCellSkin-Fibroblasts|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

SERPING1 SSC5D PCOLCE2 CD248

3.72e-05200424f777eadf571a1a6d246da87346a9cb9d511c2e81
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ROBO2 SSC5D CD248 GLI3

3.72e-0520042454806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCellFrontal_cortex-Hematopoietic-MACROPHAGE|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ARHGAP9 CPN1 TIMD4

9.26e-05934231a112bd4e5e63826efad0338ce99d7a7ad9c72b9
ToppCellFrontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ARHGAP9 CPN1 TIMD4

9.26e-05934239c566fc2a8c7630bea28e8e46df55454aa409bc1
ToppCellFrontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ARHGAP9 CPN1 TIMD4

9.26e-0593423d102a0a015a2866e3fe549ac8796b9a0d5923d7e
ToppCellFrontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ARHGAP9 CPN1 TIMD4

9.26e-05934230967a93dcc72d2d8f12d56de186ec1af55c36001
ToppCellFrontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ARHGAP9 CPN1 TIMD4

9.26e-0593423613c827a643a7b6d70ef932cfa1762e90bc5a338
ToppCellSevere-B_intermediate-14|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SREBF2 BRD3 MEGF9

3.23e-04142423f9cbc266fcea19bec504be4f3a28d1173c6b2e3c
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD8-Trm/em_CD8|GI_small-bowel / Manually curated celltypes from each tissue

JUNB TIMD4 FOXP2

3.36e-04144423a4bb274d553c29c8299354de757ecc5634008c68
DrugGliquidone [33342-05-1]; Down 200; 7.6uM; PC3; HT_HG-U133A

JUNB EAF2 ZHX2 HCFC1 MEF2C SBNO2

1.57e-061974267301_DN
DrugHeptaminol hydrochloride [543-15-7]; Up 200; 22uM; PC3; HT_HG-U133A

SREBF2 TPR JUNB CTNND2 MEGF9 SBNO2

1.62e-061984267313_UP
DrugMefenamic acid [61-68-7]; Down 200; 16.6uM; MCF7; HT_HG-U133A

SREBF2 SH3GLB1 KMT2B ZNF652 SBNO2

2.81e-051944251699_DN
DrugPantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; MCF7; HT_HG-U133A

SREBF2 MEGF9 MEF2A GLI3 ZNF652

2.95e-051964254775_DN
Drugtroglitazone; Down 200; 10uM; MCF7; HT_HG-U133A_EA

TAF4B CTNND2 MAP1S HCFC1 MPI

3.02e-051974251012_DN
DrugAcyclovir [59277-89-3]; Up 200; 17.8uM; MCF7; HT_HG-U133A

TPR TAF4B MAP1S MEF2A HCFC1

3.02e-051974251543_UP
DrugPentamidine isethionate [140-64-7]; Up 200; 6.8uM; HL60; HT_HG-U133A

CTNND2 CD248 MEF2C GLI3 SBNO2

3.10e-051984252473_UP
DrugFluocinonide [356-12-7]; Down 200; 8uM; MCF7; HT_HG-U133A

JUNB EAF2 MEF2A HCFC1 ZNF652

3.10e-051984253414_DN
DrugLactobionic acid [96-82-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A

SREBF2 CTNND2 MAP1S ZNF652 SBNO2

3.10e-051984253246_DN
DrugCloxacillin sodium salt [642-78-4]; Down 200; 8.8uM; HL60; HG-U133A

SREBF2 TPR JUNB CD248 ZNF652

3.10e-051984251443_DN
DrugBumetanide [28395-03-1]; Down 200; 11uM; MCF7; HT_HG-U133A

SREBF2 KMT2B CTNND2 HCFC1 GLI3

3.17e-051994255542_DN
DrugNatamycin [7681-93-8]; Down 200; 6uM; MCF7; HT_HG-U133A

SREBF2 JUNB KMT2B EAF2 GLI3

3.25e-052004257167_DN
Diseasemean reticulocyte volume

PCOLCE2 FOXK2 CPN1 TIMD4 ZHX2 RAPH1 MEF2C ZNF652 SBNO2

1.85e-06799439EFO_0010701
Diseaseautism spectrum disorder (implicated_via_orthology)

SHANK1 SCAMP2 CTNND2 MEF2A MEF2C

2.79e-06152435DOID:0060041 (implicated_via_orthology)
Diseasefibrinogen measurement, coronary artery disease

MAP1S RAPH1 ZNF652 LPA

7.51e-05154434EFO_0001645, EFO_0004623
Diseasetumor necrosis factor receptor superfamily member EDAR measurement

BRD3 MEF2C

1.36e-0412432EFO_0008310
Diseasemajor depressive disorder (is_implicated_in)

CTNND2 FOXP2

2.78e-0417432DOID:1470 (is_implicated_in)
DiseaseBell's palsy

ROBO2 TAF4B DNAH8

4.48e-04102433EFO_0007167
DiseaseAutistic Disorder

SHANK1 ROBO2 FOXP2 MEF2C

5.63e-04261434C0004352
Diseasecoronary artery disease, factor VII measurement

MAP1S ZNF652 LPA

5.73e-04111433EFO_0001645, EFO_0004619
Diseasefactor VIII measurement, coronary artery disease

MAP1S ZNF652 LPA

6.04e-04113433EFO_0001645, EFO_0004630
Diseaseantihyperlipidemic drug use measurement

TIMD4 CSN3 LPA

6.35e-04115433EFO_0803367
Diseasefactor XI measurement, coronary artery disease

MAP1S ZNF652 LPA

6.35e-04115433EFO_0001645, EFO_0004694
Diseasevon Willebrand factor measurement, coronary artery disease

MAP1S ZNF652 LPA

6.85e-04118433EFO_0001645, EFO_0004629
Diseasediet measurement

ROBO2 CTNND2 FOXP2 MUC17 MEF2C HCN1 LPA

7.40e-041049437EFO_0008111
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

MEF2A MEF2C

7.65e-0428432DOID:1094 (implicated_via_orthology)
DiseaseLiver carcinoma

SREBF2 KMT2B EAF2 TIMD4 LPA

8.25e-04507435C2239176
Diseasecholesteryl esters to total lipids in large LDL percentage

TIMD4 LPA

9.39e-0431432EFO_0022249
Diseasephospholipid measurement

PCOLCE2 TIMD4 LPA

1.12e-03140433EFO_0004639
Diseasefacial height measurement

CSN3 MEF2C LPA

1.17e-03142433EFO_0007856

Protein segments in the cluster

PeptideGeneStartEntry
TPFQSVPPTVSQTPV

BRD3

181

Q15059
SCSTTTPGPVIQVPE

CREB3L3

131

Q68CJ9
QLPIIPTAQPSLTTT

CD248

581

Q9HCU0
LSPIRVTSPPTVQST

CTNND2

326

Q9UQB3
VSPSVTPGVLQAVSP

ADNP2

421

Q6IQ32
TVVPQVPTSPKSSLS

RAPH1

1146

Q70E73
IQVLPTVPGSSISVP

HCFC1

461

P51610
SPLPVTALPTSVLVT

MUC16

5361

Q8WXI7
VPTVSPEVPGVVTSL

MUC16

11031

Q8WXI7
TTIPPSIPGVVTSQV

MUC16

11621

Q8WXI7
IPTVLNPVQVSSGPS

GLI3

396

P10071
TVTTPTVTTPSLPAE

MAP1S

671

Q66K74
VPPTATEGLSTSVQP

MAGEE1

296

Q9HCI5
TPVTTSTSQPPVVQT

FOXK2

456

Q01167
PIKSVIPSPTTTDVT

DNAH8

931

Q96JB1
TAPVTPITQGPSVIT

FOXP2

451

O15409
PTPVINSTFTPTTLQ

MEGF9

476

Q9H1U4
LATPVVSVATPTLPG

MEF2C

291

Q06413
VPPPTSVVTALTPTS

KMT2B

1941

Q9UMN6
KLPTTTEQPVTTTFP

PCOLCE2

271

Q9UKZ9
ATPVVSVTTPSLPPQ

MEF2A

311

Q02078
TVIASTPTTQTPIPL

MPI

376

P34949
VSGTVPVVPEPEVTS

PRPF40A

306

O75400
PTVGESLASIPQPVT

HCN1

806

O60741
PETVTVTVGPAEPTL

CPN1

396

P15169
ITLPNIEGSTPPVTV

EAF2

61

Q96CJ1
STLLTTPTVVPVPST

LPA

1356

P08519
TTEPTTQPTIQPTQP

SERPING1

91

P05155
ITSTPETTTVAVTPP

CSN3

166

P07498
PLLTSIPVSITPVTS

MUC17

806

Q685J3
TPLTSIPVSTTPVVS

MUC17

1396

Q685J3
TPLTSIPVSTTPVAI

MUC17

3046

Q685J3
VAVPTSVVTVTPGKP

TAF4B

201

Q92750
TSVTPVPSVLPNAIG

SH3GLB1

266

Q9Y371
ATTVPVTQLPGSSQP

SCAMP2

46

O15127
VETSTLSSVPPPDIT

SBNO2

221

Q9Y2G9
IPDPTTTPQPFTTIT

SSC5D

1196

A1L4H1
LRDPVTPTSPTVSVT

SHANK1

1776

Q9Y566
RPSTLIQTPTVLPTS

SPEM3

616

A0A1B0GUW6
VTPATVTNPTTTPTA

TPR

1701

P12270
TLQVKVSPTSVPTTP

SREBF2

111

Q12772
ESIPSQSPTTVIPGQ

ARHGAP9

86

Q9BRR9
PSAPPQSVTVLTVGS

ROBO2

736

Q9HCK4
GTIQSVPPTITVLPA

ZHX2

336

Q9Y6X8
VPSVVNTATTPTPPI

ZNF652

516

Q9Y2D9
TTTPAALPTTVVTTP

TIMD4

161

Q96H15
IVPNSNGVITTTPTP

JUNB

91

P17275