Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

UBA5 KIF21B ABCC4 ABCA1 MYH13 ATRX DNAH10 MYO10 KIF21A PSMC5 DICER1 DDX50 ATP11A TOP2B

1.08e-0561411414GO:0140657
GeneOntologyBiologicalProcesssynaptic signaling

GAD2 RAPSN FXR2 DTNA SYNE1 LRRK2 PSMC5 GRIN2B FABP5 ITPR1 SLC8A3 LYPD1 SERPINE2 FXR1 IGF1R GUCY1A1 PTPRN2 PLCL1 CDH1 CNR1

3.16e-0797611320GO:0099536
GeneOntologyBiologicalProcesstrans-synaptic signaling

GAD2 RAPSN FXR2 DTNA SYNE1 LRRK2 PSMC5 GRIN2B FABP5 SLC8A3 LYPD1 SERPINE2 FXR1 IGF1R GUCY1A1 PTPRN2 PLCL1 CDH1 CNR1

7.86e-0793911319GO:0099537
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

GAD2 RAPSN FXR2 DTNA SYNE1 LRRK2 PSMC5 GRIN2B SLC8A3 LYPD1 SERPINE2 FXR1 IGF1R GUCY1A1 PTPRN2 PLCL1 CDH1 CNR1

3.02e-0693111318GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

GAD2 RAPSN FXR2 DTNA SYNE1 LRRK2 PSMC5 GRIN2B SLC8A3 LYPD1 SERPINE2 FXR1 IGF1R GUCY1A1 PTPRN2 PLCL1 CDH1 CNR1

3.02e-0693111318GO:0007268
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

RAPSN FXR2 SYNE1 LRRK2 PSMC5 GRIN2B FABP5 SLC8A3 SERPINE2 FXR1 IGF1R GUCY1A1 PLCL1 CDH1 CNR1

3.45e-0666411315GO:0099177
GeneOntologyBiologicalProcessforebrain development

KIF21B ATRX FXR2 USP9X LRRK2 DICER1 FXR1 IGF1R UCHL5 CDH1 TOP2B PHLPP2

1.56e-0548911312GO:0030900
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

RAPSN FXR2 SYNE1 LRRK2 PSMC5 GRIN2B SLC8A3 SERPINE2 FXR1 IGF1R GUCY1A1 PLCL1 CDH1 CNR1

1.60e-0566311314GO:0050804
GeneOntologyBiologicalProcessbrain development

KIF21B ATRX FXR2 USP9X LRRK2 GRIN2B DICER1 SERPINE2 TTBK1 FXR1 IGF1R UCHL5 CDH1 NIPBL TOP2B PHLPP2

1.80e-0585911316GO:0007420
GeneOntologyBiologicalProcesshead development

KIF21B ATRX FXR2 USP9X LRRK2 GRIN2B DICER1 SERPINE2 TTBK1 FXR1 IGF1R UCHL5 CDH1 NIPBL TOP2B PHLPP2

4.07e-0591911316GO:0060322
GeneOntologyBiologicalProcessnegative regulation of protein maturation

LRRK2 THBS1 SERPINE2 CDH1

4.39e-05361134GO:1903318
GeneOntologyBiologicalProcessnegative regulation of protein processing

LRRK2 THBS1 SERPINE2 CDH1

4.39e-05361134GO:0010955
GeneOntologyBiologicalProcessregulation of nervous system process

SYNE1 LRRK2 GRIN2B DICER1 FABP5 SLC8A3 TENM4

5.09e-051751137GO:0031644
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

DYNLT2B IFT140 MYO10 SYNE1 SDCCAG8 LRRK2 GRIN2B SKIL ITPR1 SERPINE2 IGF1R RP1 CDH1 PREX1 CNR1

5.90e-0584611315GO:0120035
GeneOntologyBiologicalProcessretrograde trans-synaptic signaling

FABP5 GUCY1A1 CNR1

6.94e-05151133GO:0098917
GeneOntologyBiologicalProcessregulation of cell projection organization

DYNLT2B IFT140 MYO10 SYNE1 SDCCAG8 LRRK2 GRIN2B SKIL ITPR1 SERPINE2 IGF1R RP1 CDH1 PREX1 CNR1

7.38e-0586311315GO:0031344
GeneOntologyBiologicalProcesscentral nervous system development

KIF21B ATRX FXR2 USP9X LRRK2 GRIN2B DICER1 SLC8A3 SERPINE2 TTBK1 FXR1 IGF1R TENM4 UCHL5 CDH1 NIPBL TOP2B PHLPP2

8.69e-05119711318GO:0007417
GeneOntologyBiologicalProcessregulation of translation at presynapse, modulating synaptic transmission

FXR2 FXR1

8.89e-0531132GO:0099577
GeneOntologyBiologicalProcessregulation of translation at presynapse

FXR2 FXR1

8.89e-0531132GO:0140244
GeneOntologyBiologicalProcesstelencephalon development

KIF21B FXR2 USP9X LRRK2 DICER1 FXR1 IGF1R UCHL5 PHLPP2

8.96e-053321139GO:0021537
GeneOntologyBiologicalProcessregulation of synaptic transmission, glutamatergic

LRRK2 GRIN2B SERPINE2 FXR1 CNR1

1.52e-04921135GO:0051966
GeneOntologyBiologicalProcesspositive regulation of glial cell differentiation

DICER1 SERPINE2 TTBK1 TENM4

3.08e-04591134GO:0045687
GeneOntologyBiologicalProcesshippocampus development

FXR2 USP9X FXR1 IGF1R PHLPP2

3.21e-041081135GO:0021766
GeneOntologyBiologicalProcessregulation of cilium assembly

DYNLT2B IFT140 SYNE1 SDCCAG8 RP1

3.21e-041081135GO:1902017
GeneOntologyBiologicalProcessnegative regulation of cGMP-mediated signaling

THBS1 PDE11A

4.40e-0461132GO:0010754
GeneOntologyBiologicalProcessretrograde trans-synaptic signaling by lipid

FABP5 CNR1

4.40e-0461132GO:0098920
GeneOntologyBiologicalProcessretrograde trans-synaptic signaling by endocannabinoid

FABP5 CNR1

4.40e-0461132GO:0098921
GeneOntologyBiologicalProcessmodulation of excitatory postsynaptic potential

SYNE1 LRRK2 GRIN2B SLC8A3

4.47e-04651134GO:0098815
GeneOntologyCellularComponentsomatodendritic compartment

KIF21B GAD2 FXR2 MYO10 SYNE1 KIF21A LRRK2 MAGOHB GRIN2B KCNIP1 DICER1 ITPR1 SLC8A3 SERPINE2 TTBK1 FXR1 IGF1R AIF1 WDFY3 PREX1 PDE11A

3.59e-06122811621GO:0036477
GeneOntologyCellularComponentaxon

KIF21B GAD2 DTNA USP9X KIF21A LRRK2 GRIN2B DICER1 SLC8A3 FXR1 IGF1R PTPRN2 WDFY3 CDH1 PREX1 CNR1

3.32e-0589111616GO:0030424
GeneOntologyCellularComponentpostsynapse

RPL21 KIF21B RAPSN ATR FXR2 USP9X SYNE1 LRRK2 PSMC5 GRIN2B DICER1 FABP5 ITPR1 SLC8A3 FXR1 IGF1R CDH1

4.60e-05101811617GO:0098794
GeneOntologyCellularComponentdistal axon

KIF21B USP9X LRRK2 GRIN2B DICER1 SLC8A3 PTPRN2 CDH1 PREX1 CNR1

1.57e-0443511610GO:0150034
GeneOntologyCellularComponentperinuclear region of cytoplasm

GAD2 ABCA1 RASA2 SYNE1 UNC45A DICER1 ITPR1 CCNF FAT1 SLC8A3 TTBK1 FXR1 AIF1 CDH1 PREX1

2.05e-0493411615GO:0048471
GeneOntologyCellularComponentneuronal cell body

GAD2 MYO10 LRRK2 MAGOHB GRIN2B KCNIP1 ITPR1 SLC8A3 SERPINE2 TTBK1 IGF1R AIF1 WDFY3 PDE11A

2.19e-0483511614GO:0043025
GeneOntologyCellularComponentmicrotubule associated complex

KIF21B DYNLT2B DNAH10 KIF21A TTBK1 RP1

2.81e-041611166GO:0005875
GeneOntologyCellularComponentmyosin filament

MYH13 MYOM2 MYBPC2

3.50e-04251163GO:0032982
GeneOntologyCellularComponentplatelet dense granule membrane

ABCC4 ITPR1

4.51e-0461162GO:0031088
GeneOntologyCellularComponentglutamatergic synapse

KIF21B FXR2 LRRK2 STK38 GRIN2B DICER1 FABP5 FXR1 IGF1R TENM4 GUCY1A1 CDH1 CNR1

6.08e-0481711613GO:0098978
GeneOntologyCellularComponentcytosolic proteasome complex

PSMC5 UCHL5

6.30e-0471162GO:0031597
GeneOntologyCellularComponentcell body

GAD2 MYO10 LRRK2 MAGOHB GRIN2B KCNIP1 ITPR1 SLC8A3 SERPINE2 TTBK1 IGF1R AIF1 WDFY3 PDE11A

6.36e-0492911614GO:0044297
GeneOntologyCellularComponentmyofibril

MYH13 SYNE1 GRIN2B FXR1 XIRP2 MYOM2 MYBPC2

8.34e-042731167GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

MYH13 SYNE1 GRIN2B FXR1 XIRP2 MYOM2 MYBPC2

1.18e-032901167GO:0043292
GeneOntologyCellularComponenttransport vesicle membrane

GAD2 ATR LRRK2 GRIN2B ITPR1 PTPRN2 SCG3

1.26e-032931167GO:0030658
DomainFXR_C1

FXR2 FXR1

3.69e-0521142IPR032172
DomainFXR_C1

FXR2 FXR1

3.69e-0521142PF16096
DomainAgenet

FXR2 FXR1

1.10e-0431142PF05641
DomainAGENET_LIKE

FXR2 FXR1

1.10e-0431142PS51641
DomainFXMRP1_C_core

FXR2 FXR1

1.10e-0431142IPR022034
DomainAgenet-like_dom

FXR2 FXR1

1.10e-0431142IPR008395
DomainFXMRP1_C_core

FXR2 FXR1

1.10e-0431142PF12235
DomainP-loop_NTPase

KIF21B ABCC4 ABCA1 MYH13 ATRX DNAH10 MYO10 KIF21A LRRK2 BMS1 PSMC5 DICER1 EFTUD2 NWD2 DDX50

1.99e-0484811415IPR027417
DomainARM-type_fold

ATR USP9X LRRK2 UNC45A ITPR1 WDFY3 ARMH3 NIPBL TARBP1

2.34e-043391149IPR016024
DomainWD40

KIF21B IFT140 WDR64 KIF21A LRRK2 WDR3 NWD2 WDFY3

2.40e-042681148SM00320
DomainWD40_repeat

KIF21B IFT140 WDR64 KIF21A LRRK2 WDR3 NWD2 WDFY3

2.65e-042721148IPR001680
DomainGST_alpha

GSTA3 GSTA5

3.65e-0451142IPR003080
DomainWD40_repeat_dom

KIF21B IFT140 WDR64 KIF21A LRRK2 WDR3 NWD2 WDFY3

4.77e-042971148IPR017986
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RPL21 SLC25A24 REXO4 HK2 ATR ATRX DNAH10 POLA1 USP9X SYNE1 POLR2A BMS1 PEPD PSMC5 UNC45A SSRP1 PRPF40A DICER1 EFTUD2 WDR3 FXR1 DDX50 UCHL5 NIPBL TOP2B

7.49e-1214251162530948266
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

RPL21 UBA5 POLA1 USP9X POLR2A NELFB PSMC5 UNC45A SSRP1 EFTUD2 WDR3 FXR1 COQ8A TUBGCP3 TOP2B

3.80e-096381161533239621
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

REXO4 FXR2 SYNE1 POLR2A BMS1 SSRP1 PRPF40A WDR3 FXR1 UTP11 TOP2B

1.64e-083321161125693804
Pubmed

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.

REXO4 POLR2A BMS1 SSRP1 EFTUD2 WDR3 DDX50 UTP11 MRPL24 NIPBL

1.80e-082591161030404004
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RPL21 REXO4 HK2 RASA2 POLA1 KIF21A POLR2A BMS1 PSMC5 UNC45A SSRP1 FABP5 EFTUD2 WDR3 FXR1 DDX50 TUBGCP3 WDFY3 NIPBL TOP2B

2.20e-0813531162029467282
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

ATRX FXR2 USP9X POLR2A SSRP1 DICER1 ITPR1 WDR3 FXR1 DDX50 CDH1 TOP2B

3.04e-084401161234244565
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

RPL21 ATRX USP9X POLR2A ITPR1 THBS1 SERPINE2 NWD2 FXR1 TENM4 TUBGCP3 TOP2B

7.00e-084751161231040226
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

RPL21 KIF21B REXO4 FXR2 MYO10 POLR2A BMS1 SSRP1 PRPF40A DICER1 WDR3 FXR1 DDX50 UCHL5

1.43e-077231161434133714
Pubmed

Nucleolar proteome dynamics.

RPL21 ATR ATRX BMS1 SSRP1 EFTUD2 WDR3 DDX50 UTP11 NIPBL TOP2B

1.72e-074191161115635413
Pubmed

ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.

FXR2 KIF21A BMS1 MAGOHB SSRP1 PRPF40A EFTUD2 FXR1 DDX50 TOP2B

1.73e-073301161033301849
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

RPL21 ATRX POLR2A MAGOHB PSMC5 PRPF40A FABP5 ITPR1 EFTUD2 DDX50 DCLRE1A NIPBL TOP2B

2.95e-076521161331180492
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RPL21 REXO4 FXR2 POLA1 USP9X POLR2A BMS1 PSMC5 PRPF40A DICER1 WDR3 FXR1 NIPBL

3.00e-076531161322586326
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SLC25A24 REXO4 SYNE1 POLR2A BMS1 STK38 SSRP1 PRPF40A EFTUD2 NWD2 DDX50 SCG3 TUBGCP3 SRPX NIPBL TOP2B

6.51e-0710821161638697112
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

RPL21 REXO4 FXR2 BMS1 C19orf47 SSRP1 PRPF40A FABP5 EFTUD2 WDR3 DDX50 TOP2B

9.16e-076051161228977666
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RPL21 REXO4 FXR2 BMS1 UNC45A SSRP1 PRPF40A EFTUD2 WDR3 FXR1 DDX50 TUBGCP3 MRPL24 TOP2B

9.46e-078471161435850772
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

RPL21 SLC25A24 REXO4 FXR2 BMS1 MAGOHB UNC45A SSRP1 EFTUD2 WDR3 THBS1 FXR1 DDX50 UTP11 GAN CDH1 MRPL24

9.63e-0712571161736526897
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

RPL21 DOCK4 ATRX FXR2 USP9X POLR2A NELFB PSMC5 UNC45A PRPF40A FABP5 EFTUD2 FBLN1 TTBK1 IGF1R PIP5K1B PREX1

1.29e-0612841161717353931
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

FXR2 MYO10 DTNA POLA1 BMS1 PSMC5 UNC45A DICER1 EFTUD2 WDR3 UCHL5 TUBGCP3 SRPX TARBP1 PHLPP2

1.34e-0610051161519615732
Pubmed

A protein interaction landscape of breast cancer.

DOCK4 HK2 FXR2 USP9X POLR2A PIK3R3 SSRP1 FABP5 FXR1 DDX50 CDH1 TOP2B

1.49e-066341161234591612
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RPL21 USP9X SYNE1 POLR2A C19orf47 PSMC5 SSRP1 PRPF40A DICER1 EFTUD2 WDR3 FXR1 DDX50 NIPBL TOP2B

1.69e-0610241161524711643
Pubmed

Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.

ATRX FXR2 POLR2A BMS1 STK38 SSRP1 PRPF40A EFTUD2 FXR1 DDX50

2.39e-064411161031239290
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

RPL21 REXO4 FXR2 SYNE1 POLR2A BMS1 MAGOHB SSRP1 PRPF40A EFTUD2 FXR1 DDX50 UTP11

3.14e-068071161322681889
Pubmed

Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis.

ABCC4 PSMC5 UCHL5 EPCAM

3.45e-0631116426222436
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

UBA5 ATR ATRX KIF21A PSMC5 UNC45A PRPF40A EFTUD2 UCHL5 TUBGCP3 NIPBL

4.23e-065821161120467437
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

RPL21 FXR2 SYNE1 POLR2A STK38 MAGOHB SSRP1 PRPF40A EFTUD2 FXR1 DDX50 TOP2B

5.02e-067141161228302793
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

GAD2 LURAP1 ATRX USP9X SYNE1 KIF21A GRIN2B SKIL WDR3 THBS1 SERPINE2 SCG3 WDFY3 PREX1 NIPBL TARBP1

5.92e-0612851161635914814
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RPL21 MYH13 ATRX DTNA SYNE1 KIF21A SSRP1 FXR1 DDX50 SCG3 ATP11A MYOM2 CDH1 PREX1 NIPBL TOP2B MYBPC2

6.06e-0614421161735575683
Pubmed

Directed proteomic analysis of the human nucleolus.

ATR BMS1 WDR3 DDX50 UTP11 RP1 TOP2B

6.65e-06208116711790298
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

KIF21B MYH13 USP9X POLR2A IGF1R XIRP2 GAN MYOM2 RP1 ARMH3

6.85e-064971161036774506
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

RPL21 FXR2 USP9X POLR2A BMS1 NELFB SSRP1 EFTUD2 FXR1 DDX50 TOP2B

7.11e-066151161131048545
Pubmed

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.

RPL21 USP9X POLR2A DICER1 EFTUD2 DDX50 TUBGCP3 NAA30

7.92e-06300116828561026
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DYNLT2B ABCC4 ATRX RASA2 DTNA RNF144A SDCCAG8 PIK3R3 TOM1L1 PEPD IGF1R COQ8A GUCY1A1 PTPRN2 SLC9A7 ATP11A PNPLA7

9.21e-0614891161728611215
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

WDR64 RASA2 FXR2 USP9X THBS1 COQ8A PTPRN2 WDFY3 PREX1 NIPBL TARBP1

1.00e-056381161131182584
Pubmed

Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B.

KIF21B KIF21A

1.10e-052116210225949
Pubmed

Cadherin-dependent filopodia control preimplantation embryo compaction.

MYO10 CDH1

1.10e-052116224270889
Pubmed

An integrated workflow for 2D and 3D posture analysis during vestibular system testing in mice.

GAD2 POLR2A

1.10e-052116238107632
Pubmed

Structural studies of the tandem Tudor domains of fragile X mental retardation related proteins FXR1 and FXR2.

FXR2 FXR1

1.10e-052116221072162
Pubmed

α-Dystrobrevin knockout mice have increased motivation for appetitive reward and altered brain cannabinoid receptor 1 expression.

DTNA CNR1

1.10e-052116236045406
Pubmed

Glutamate Attenuates the Survival Property of IGFR through NR2B Containing N-Methyl-D-aspartate Receptors in Cortical Neurons.

GRIN2B IGF1R

1.10e-052116232849999
Pubmed

Prognostic significance of paired epithelial cell adhesion molecule and E-cadherin in ovarian serous carcinoma.

CDH1 EPCAM

1.10e-052116219157508
Pubmed

Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations.

FXR2 FXR1

1.10e-052116210196376
Pubmed

A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation.

CDH1 PREX1

1.10e-052116221179475
Pubmed

ATP and ACh Evoked Calcium Transients in the Neonatal Mouse Cochlear and Vestibular Sensory Epithelia.

GAD2 POLR2A

1.10e-052116234566562
Pubmed

The structure of an FF domain from human HYPA/FBP11.

POLR2A PRPF40A

1.10e-052116212381297
Pubmed

Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse.

POLR2A AIF1

1.10e-052116226005403
Pubmed

EpCAM-independent isolation of circulating tumor cells with epithelial-to-mesenchymal transition and cancer stem cell phenotypes using ApoStream® in patients with breast cancer treated with primary systemic therapy.

CDH1 EPCAM

1.10e-052116232214335
Pubmed

Comparative genomic sequence analysis of the FXR gene family: FMR1, FXR1, and FXR2.

FXR2 FXR1

1.10e-052116211735223
Pubmed

Spontaneous and Acetylcholine Evoked Calcium Transients in the Developing Mouse Utricle.

GAD2 POLR2A

1.10e-052116231133810
Pubmed

Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells.

CYP2E1 DICER1

1.10e-052116233232872
Pubmed

Developmental GAD2 Expression Reveals Progenitor-like Cells with Calcium Waves in Mammalian Crista Ampullaris.

GAD2 POLR2A

1.10e-052116232771977
Pubmed

D-ꞵ-hydroxybutyrate stabilizes hippocampal CA3-CA1 circuit during acute insulin resistance.

GAD2 POLR2A

1.10e-052116238818236
Pubmed

Phosphorylation of P-Rex1 at serine 1169 participates in IGF-1R signaling in breast cancer cells.

IGF1R PREX1

1.10e-052116223899556
Pubmed

Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.

FXR2 MYO10 SYNE1 STK38 EFTUD2 THBS1 FXR1 TOP2B

1.29e-05321116832098917
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

MYH13 SYNE1 PRPF40A EFTUD2 FXR1 DDX50 TOP2B

1.43e-05234116736243803
Pubmed

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.

RPL21 FXR2 BMS1 MAGOHB SSRP1 EFTUD2 WDR3 DDX50 TOP2B

1.47e-05430116938172120
Pubmed

LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.

HK2 FXR2 MAGOHB SSRP1 FABP5 EFTUD2 FXR1 TOP2B

1.48e-05327116831409639
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

HK2 ATRX POLA1 USP9X POLR2A PSMC5 EFTUD2 NIPBL

1.65e-05332116832786267
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

RPL21 FXR2 MYO10 SYNE1 UNC45A SSRP1 PRPF40A ITPR1 EFTUD2 WDR3 FXR1 DDX50 UTP11

1.77e-059491161336574265
Pubmed

Impact of lactobacilli on orally acquired listeriosis.

CYP2E1 CCDC186 GSTA3 GSTA5 IFIT1B CDH1

1.81e-05162116623012479
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

RPL21 HK2 FXR2 POLA1 USP9X KIF21A POLR2A NELFB MAGOHB UNC45A SSRP1 EFTUD2 FXR1 NIPBL TARBP1 TOP2B

1.95e-0514151161628515276
Pubmed

The eutheria-specific miR-290 cluster modulates placental growth and maternal-fetal transport.

ENDOU CDH1 EPCAM

1.96e-0516116328935707
Pubmed

Mapping Extracellular Protein-Protein Interactions Using Extracellular Proximity Labeling (ePL).

MAGOHB PSMC5 EFTUD2 FBLN1 THBS1 SERPINE2 SRPX

2.02e-05247116739238192
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

IFT140 FXR2 POLR2A PIK3R3 SSRP1 SKIL PRPF40A DICER1 FAT1 FXR1 COQ8A TUBGCP3 WDFY3 TCF7L1

2.19e-0511161161431753913
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

ATRX POLR2A MAGOHB SSRP1 DICER1 DDX50 TOP2B

2.24e-05251116728077445
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

GAD2 GRIN2B DICER1 IGF1R PTPRN2 TOP2B

2.46e-05171116620201926
Pubmed

SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.

FXR2 SYNE1 MAGOHB PSMC5 PRPF40A EFTUD2 WDR3 FXR1 COQ8A

2.63e-05463116934901782
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

RPL21 ATR ATRX POLR2A MAGOHB SSRP1 SKIL PRPF40A EFTUD2 WDR3 DDX50 UCHL5 DCLRE1A NIPBL TOP2B

2.73e-0512941161530804502
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

RPL21 UBA5 HK2 POLA1 USP9X KIF21A POLR2A TOM1L1 PEPD NELFB PSMC5 UNC45A SSRP1 EFTUD2 SERPINE2 UCHL5

2.73e-0514551161622863883
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

RPL21 FXR2 USP9X BMS1 MAGOHB PRPF40A EFTUD2 FXR1 DDX50 MRPL24 TOP2B

2.79e-057131161129802200
Pubmed

Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer.

USP9X POLR2A PRPF40A TOP2B

2.81e-0552116424591637
Pubmed

Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis.

USP9X ITPR1 NIPBL

2.84e-0518116333323119
Pubmed

Spatial control of nucleoporin condensation by fragile X-related proteins.

FXR2 FXR1

3.30e-053116232706158
Pubmed

The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2.

FXR2 FXR1

3.30e-05311627489725
Pubmed

Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them.

FXR2 FXR1

3.30e-05311628668200
Pubmed

Cloning of human p55 gamma, a regulatory subunit of phosphatidylinositol 3-kinase, by a yeast two-hybrid library screen with the insulin-like growth factor-I receptor.

PIK3R3 IGF1R

3.30e-05311629524259
Pubmed

Sub-synaptic, multiplexed analysis of proteins reveals Fragile X related protein 2 is mislocalized in Fmr1 KO synapses.

FXR2 FXR1

3.30e-053116227770568
Pubmed

An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learning.

POLR2A CNR1

3.30e-053116236566254
Pubmed

Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs.

FXR2 FXR1

3.30e-053116219487368
Pubmed

Extracellular Prolidase (PEPD) Induces Anabolic Processes through EGFR, β1-integrin, and IGF-1R Signaling Pathways in an Experimental Model of Wounded Fibroblasts.

PEPD IGF1R

3.30e-053116233477899
Pubmed

Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P.

FXR2 FXR1

3.30e-053116220442204
Pubmed

IGF-1R inhibition sensitizes breast cancer cells to ATM-related kinase (ATR) inhibitor and cisplatin.

ATR IGF1R

3.30e-053116227472395
Pubmed

LLPS of FXR proteins drives replication organelle clustering for β-coronaviral proliferation.

FXR2 FXR1

3.30e-053116238587486
Pubmed

Small interfering RNAs against the TAR RNA binding protein, TRBP, a Dicer cofactor, inhibit human immunodeficiency virus type 1 long terminal repeat expression and viral production.

DICER1 TARBP1

3.30e-053116217360756
Pubmed

Regulation of cell-cell adhesion in prostate cancer cells by microRNA-96 through upregulation of E-Cadherin and EpCAM.

CDH1 EPCAM

3.30e-053116231738404
Pubmed

Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma.

PIK3R3 IGF1R

3.30e-053116217360667
Pubmed

Insulin-like Growth Factor 1 Receptor Signaling Is Required for Optimal ATR-CHK1 Kinase Signaling in Ultraviolet B (UVB)-irradiated Human Keratinocytes.

ATR IGF1R

3.30e-053116227979966
Pubmed

Neurobeachin and the Kinesin KIF21B Are Critical for Endocytic Recycling of NMDA Receptors and Regulate Social Behavior.

KIF21B GRIN2B

3.30e-053116229847800
Pubmed

Multiple microRNAs within the 14q32 cluster target the mRNAs of major type 1 diabetes autoantigens IA-2, IA-2β, and GAD65.

GAD2 PTPRN2

3.30e-053116226148972
Pubmed

Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis.

FXR2 FXR1

3.30e-05311629259278
Pubmed

Electroacupuncture Potentiates Cannabinoid Receptor-Mediated Descending Inhibitory Control in a Mouse Model of Knee Osteoarthritis.

GAD2 CNR1

3.30e-053116229681797
Pubmed

LRRK2 Gly2019Ser Mutation Promotes ER Stress via Interacting with THBS1/TGF-β1 in Parkinson's Disease.

LRRK2 THBS1

3.30e-053116237672887
Pubmed

Identification of downstream metastasis-associated target genes regulated by LSD1 in colon cancer cells.

CABYR CDH1

3.30e-053116228121627
Pubmed

Fragile X-related proteins regulate mammalian circadian behavioral rhythms.

FXR2 FXR1

3.30e-053116218589395
Pubmed

Characterization of the TRBP domain required for dicer interaction and function in RNA interference.

DICER1 TARBP1

3.30e-053116219422693
Pubmed

ABC transporters as differentiation markers in glioblastoma cells.

ABCC4 ABCA1

3.30e-053116225028266
Pubmed

Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression.

FXR2 FXR1

3.30e-053116212417522
Pubmed

The FAM deubiquitylating enzyme localizes to multiple points of protein trafficking in epithelia, where it associates with E-cadherin and beta-catenin.

USP9X CDH1

3.30e-053116214742711
Pubmed

Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA.

POLR2A DICER1

3.30e-053116224814348
Pubmed

MACF1 links Rapsyn to microtubule- and actin-binding proteins to maintain neuromuscular synapses.

RAPSN TOP2B

3.30e-053116230842214
Pubmed

Promoter methylation of DAPK1, E-cadherin and thrombospondin-1 in de novo and therapy-related myeloid neoplasms.

THBS1 CDH1

3.30e-053116220655775
InteractionSNIP1 interactions

REXO4 ATR POLR2A BMS1 SSRP1 PRPF40A EFTUD2 WDR3 DDX50 UTP11 AIF1 MRPL24 NIPBL

6.91e-0741711413int:SNIP1
InteractionSEC24C interactions

DTNA USP9X MAGOHB UNC45A SSRP1 EFTUD2 CCNF FXR1 IGF1R

2.73e-062071149int:SEC24C
InteractionH3C1 interactions

REXO4 ATRX POLA1 SYNE1 POLR2A LRRK2 NELFB MAGOHB SSRP1 SUV39H2 EFTUD2 FBLN1 THBS1 XIRP2 CDH1 NIPBL TARBP1 TOP2B

3.00e-0690111418int:H3C1
InteractionSNW1 interactions

UBA5 ATR ATRX KIF21A MAGOHB PSMC5 UNC45A SSRP1 SKIL PRPF40A EFTUD2 CCNF FXR1 UCHL5 TUBGCP3 NIPBL

4.72e-0674711416int:SNW1
InteractionBRCA1 interactions

RPL21 CFAP47 DOCK4 DYNLT2B HK2 ATR FXR2 DTNA USP9X POLR2A NELFB PSMC5 SSRP1 ITPR1 EFTUD2 CABYR UCHL5 DCLRE1A CDH1 NIPBL TOP2B

6.18e-06124911421int:BRCA1
InteractionCCDC92 interactions

LURAP1 FXR2 PSMC5 FXR1 UCHL5

1.23e-05531145int:CCDC92
InteractionSIRT6 interactions

ATRX FXR2 USP9X POLR2A SSRP1 DICER1 ITPR1 EFTUD2 WDR3 FAT1 FXR1 DDX50 CDH1 TOP2B

1.25e-0562811414int:SIRT6
InteractionCBS interactions

UBA5 ATRX FXR2 EFTUD2 CCNF FXR1 PREX1

1.29e-051371147int:CBS
InteractionSTIP1 interactions

RPL21 UBA5 POLA1 USP9X POLR2A LRRK2 NELFB PSMC5 UNC45A SSRP1 FABP5 EFTUD2 CCNF WDR3 FXR1 COQ8A TUBGCP3 TOP2B

1.36e-05100611418int:STIP1
InteractionMST1R interactions

RPL21 WDR64 ATR DNAH10 POLA1 SYNE1 UNC45A PRPF40A

1.83e-052001148int:MST1R
InteractionUBR4 interactions

RAPSN MYO10 USP9X KIF21A STK38 PSMC5 PRPF40A EFTUD2 CCNF TUBGCP3

2.03e-0533411410int:UBR4
InteractionTERF2 interactions

FXR2 MYO10 USP9X SYNE1 PIK3R3 MAGOHB SSRP1 PRPF40A MYOM2 ARMH3

2.36e-0534011410int:TERF2
InteractionEIF4A3 interactions

RPL21 DOCK4 BMS1 C19orf47 STK38 MAGOHB UNC45A SSRP1 PRPF40A EFTUD2 CCNF IGF1R

2.61e-0549911412int:EIF4A3
InteractionKIF21A interactions

KIF21B USP9X KIF21A EFTUD2 CCNF FXR1

2.93e-051051146int:KIF21A
InteractionPPME1 interactions

HK2 S100A7L2 SYNE1 TOM1L1 UNC45A CCNF CDH1

2.99e-051561147int:PPME1
InteractionENO1 interactions

WDR64 HK2 ATR POLA1 LRRK2 UNC45A SSRP1 FABP5 EFTUD2 CCNF CABYR FXR1 SCG3 CDH1

4.20e-0570111414int:ENO1
InteractionNPM1 interactions

RPL21 DOCK4 REXO4 ATR FXR2 BMS1 STK38 PSMC5 SSRP1 DICER1 EFTUD2 CCNF WDR3 FXR1 DDX50 GAN RP1 MRPL24 TOP2B

4.21e-05120111419int:NPM1
InteractionIFI16 interactions

REXO4 FXR2 SYNE1 POLR2A BMS1 STK38 SSRP1 PRPF40A EFTUD2 WDR3 FXR1 DDX50 UTP11 TOP2B

5.12e-0571411414int:IFI16
InteractionFBXO22 interactions

KIF21B MYH13 USP9X POLR2A EFTUD2 CCNF IGF1R XIRP2 GAN MYOM2 RP1 ARMH3

5.60e-0554011412int:FBXO22
InteractionPOLR2E interactions

POLR2A NELFB STK38 SSRP1 PRPF40A CCNF COQ8A UTP11 CDH1

6.44e-053081149int:POLR2E
InteractionAAMP interactions

FXR2 SSRP1 PRPF40A DICER1 CCNF

6.68e-05751145int:AAMP
InteractionPSMB5 interactions

RNF144A LRRK2 PSMC5 EFTUD2 CCNF UCHL5 PREX1 TOP2B

7.09e-052421148int:PSMB5
InteractionSIRT7 interactions

RPL21 REXO4 ATR FXR2 POLA1 USP9X POLR2A BMS1 PSMC5 PRPF40A DICER1 WDR3 FXR1 NIPBL

7.95e-0574411414int:SIRT7
InteractionNOP56 interactions

RPL21 REXO4 ATRX BMS1 SSRP1 EFTUD2 CCNF WDR3 FXR1 DDX50 CDH1 TOP2B

9.36e-0557011412int:NOP56
InteractionCDC5L interactions

UBA5 ATR SYNE1 KIF21A POLR2A BMS1 PSMC5 UNC45A PRPF40A EFTUD2 CCNF FXR1 UCHL5 TUBGCP3 NIPBL

9.52e-0585511415int:CDC5L
InteractionMAU2 interactions

STK38 SSRP1 PRPF40A FABP5 NIPBL TOP2B

1.24e-041361146int:MAU2
InteractionMAGOH interactions

RPL21 DOCK4 STK38 MAGOHB SSRP1 EFTUD2 FXR1 CDH1

1.30e-042641148int:MAGOH
InteractionSUMO2 interactions

HK2 ATRX POLA1 USP9X POLR2A LRRK2 PSMC5 SSRP1 FABP5 EFTUD2 NIPBL TOP2B

1.31e-0459111412int:SUMO2
InteractionHECTD1 interactions

RPL21 REXO4 FXR2 USP9X BMS1 C19orf47 SSRP1 PRPF40A EFTUD2 CCNF WDR3 FXR1 DDX50 TUBGCP3 CDH1 TOP2B

1.33e-0498411416int:HECTD1
InteractionWASF2 interactions

POLA1 PSMC5 PRPF40A EFTUD2 IGF1R CDH1

1.83e-041461146int:WASF2
InteractionDOT1L interactions

RPL21 REXO4 ATRX FXR2 BMS1 UNC45A SSRP1 PRPF40A EFTUD2 WDR3 FXR1 DDX50 TUBGCP3 TOP2B

1.86e-0480711414int:DOT1L
InteractionPHC1P1 interactions

FXR2 FXR1

1.89e-0441142int:PHC1P1
InteractionRDX interactions

MYO10 FABP5 EFTUD2 CCNF FXR1 GAN CDH1 PHLPP2

2.14e-042841148int:RDX
InteractionPA2G4 interactions

RPL21 UBA5 ATR LRRK2 NELFB EFTUD2 TARBP1 MYBPC2

2.14e-042841148int:PA2G4
InteractionMSANTD3 interactions

FXR2 FXR1 CDH1

2.18e-04211143int:MSANTD3
InteractionCSNK2B interactions

DYNLT2B ATRX FXR2 POLR2A BMS1 GRIN2B SSRP1 EFTUD2 CCNF FXR1 UCHL5 TOP2B

2.20e-0462511412int:CSNK2B
InteractionMEN1 interactions

RPL21 REXO4 ATRX FXR2 POLA1 POLR2A BMS1 UNC45A SSRP1 PRPF40A EFTUD2 WDR3 FXR1 DDX50 MRPL24 TOP2B

2.20e-04102911416int:MEN1
InteractionAIRE interactions

ATR POLR2A SSRP1 EFTUD2 FAT1

2.26e-04971145int:AIRE
InteractionMRE11 interactions

ATR ATRX POLA1 NELFB EFTUD2 CCNF SCG3 CDH1

2.29e-042871148int:MRE11
InteractionARHGEF7 interactions

FXR2 LRRK2 EFTUD2 CCNF FXR1 PREX1

2.36e-041531146int:ARHGEF7
InteractionZBTB2 interactions

FXR2 KIF21A BMS1 MAGOHB SSRP1 PRPF40A EFTUD2 FXR1 DDX50 TOP2B

2.40e-0445011410int:ZBTB2
InteractionCCT8 interactions

UBA5 SYNE1 KIF21A LRRK2 NELFB PSMC5 SUV39H2 EFTUD2 CCNF GAN CDH1

2.88e-0455011411int:CCT8
GeneFamilyFibronectin type III domain containing|I-set domain containing|Myosin binding proteins

MYOM2 MYBPC2

5.06e-048782658
GeneFamilyWD repeat domain containing

KIF21B IFT140 WDR64 KIF21A WDR3 WDFY3

9.39e-04262786362
GeneFamilyX-linked mental retardation|RNA helicases

ATRX DICER1

9.85e-04117821168
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DOCK4 SLC25A24 ATR ATRX MYO10 USP9X DICER1 ITPR1 FAT1 FXR1 IGF1R TUBGCP3 WDFY3 NIPBL PHLPP2

5.81e-0685611615M4500
CoexpressionSIMBULAN_UV_RESPONSE_NORMAL_DN

POLR2A CCNF THBS1 CDH1

1.35e-05331164M16114
CoexpressionFOROUTAN_PRODRANK_TGFB_EMT_UP

DOCK4 ABCA1 MYO10 SKIL THBS1 SERPINE2 SRPX

1.90e-051851167M42503
CoexpressionWANG_CISPLATIN_RESPONSE_AND_XPC_UP

KIF21A RNF144A PSMC5 THBS1 PTPRN2 CDH1 TARBP1

1.90e-051851167M19511
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_UP

RPL21 DYNLT2B ATR ATRX DTNA POLA1 PRPF40A FXR1 UCHL5 NAA30 NIPBL

2.14e-0552311611M12707
CoexpressionFOROUTAN_TGFB_EMT_UP

DOCK4 ABCA1 MYO10 SKIL THBS1 SERPINE2 SRPX

2.41e-051921167M42501
CoexpressionFUJII_YBX1_TARGETS_DN

DTNA SSRP1 PRPF40A FABP5 ITPR1 CCNF CDCA7

2.58e-051941167M14340
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_UP

RPL21 DYNLT2B ATR ATRX DTNA POLA1 PRPF40A FXR1 UCHL5 NAA30 NIPBL

2.59e-0553411611MM1054
CoexpressionGSE22033_WT_VS_PPARG_KO_MEF_UP

ATR DIPK1A TOM1L1 FBLN1 SERPINE2 GUCY1A1 PHLPP2

2.66e-051951167M7694
CoexpressionGSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN

RAPSN THBS1 LYPD1 COQ8A PIP5K1B WDFY3 TARBP1

2.84e-051971167M3472
CoexpressionGSE360_L_DONOVANI_VS_L_MAJOR_DC_UP

SLC25A24 ATRX POLA1 PRPF40A DICER1 PIP5K1B WDFY3

3.13e-052001167M5192
CoexpressionGSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_UP

SLC25A24 DTNA POLA1 FXR1 GUCY1A1 SCG3 DCLRE1A

3.13e-052001167M4355
CoexpressionHALLMARK_UV_RESPONSE_DN

ATRX RASA2 SYNE1 PIK3R3 IGF1R NIPBL

4.47e-051441166M5942
CoexpressionLAKE_ADULT_KIDNEY_C20_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_A_CORTEX

ABCC4 MYO10 KIF21A ITPR1 SLC26A7 PLCL1

6.05e-051521166M39239
CoexpressionNAKAYA_MYELOID_DENDRITIC_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_UP

ATR DTNA POLA1 DIPK1A USP9X STK38 ITPR1 NIPBL TARBP1

7.29e-053991169M41172
CoexpressionBURTON_ADIPOGENESIS_3

ABCA1 POLA1 CCNF CDCA7 RNASEH2C

8.79e-051011165M1577
CoexpressionGSE21033_3H_VS_24H_POLYIC_STIM_DC_UP

MYO10 POLR2A ITPR1 CABYR GUCY1A1 PREX1

9.84e-051661166M7722
CoexpressionBURTON_ADIPOGENESIS_3

ABCA1 POLA1 CCNF CDCA7 RNASEH2C

1.01e-041041165MM1180
CoexpressionHEVNER_CORTEX_RADIAL_GLIA_PROGENITORS

ATR POLA1 SSRP1 CCNF FAT1 CDCA7 SLC26A7 RNASEH2C TCF7L1

1.33e-044321169MM419
CoexpressionDODD_NASOPHARYNGEAL_CARCINOMA_UP

DOCK4 UBA5 ATR POLA1 SDCCAG8 MAGOHB SUV39H2 PRPF40A CCNF WDR3 FXR1 DDX50 CDCA7 UCHL5 SLC9A7 MRPL24 TARBP1

1.53e-04140711617M14427
CoexpressionLAKE_ADULT_KIDNEY_C6_PROXIMAL_TUBULE_EPITHELIAL_CELLS_FIBRINOGEN_POS_S3

ABCC4 KIF21A LRRK2 DICER1 SERPINE2 ATP11A

1.58e-041811166M39225
CoexpressionTUOMISTO_TUMOR_SUPPRESSION_BY_COL13A1_DN

CYP2E1 GSTA3 GSTA5

1.60e-04241163MM708
CoexpressionTHAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_7DY_UP

DYNLT2B ABCC4 FXR2 DIPK1A STK38 PRPF40A FXR1 DDX50 MRPL24 NIPBL TOP2B

1.66e-0465811611M40871
CoexpressionJECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN

ITPR1 THBS1 CDH1 EPCAM

1.67e-04621164M1417
CoexpressionJECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN

ITPR1 THBS1 CDH1 EPCAM

1.77e-04631164MM1147
CoexpressionFOROUTAN_INTEGRATED_TGFB_EMT_UP

DOCK4 SKIL THBS1 SERPINE2 SRPX

1.98e-041201165M42505
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HOPC

RNF144A LRRK2 KCNIP1 FABP5 SERPINE2 SCG3 SLC9A7 PREX1

2.30e-043661168M39052
CoexpressionDEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN

ATR MYO10 POLR2A DICER1 ITPR1 SERPINE2 MYOM2

2.34e-042761167M3063
CoexpressionGSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP

KIF21B ATRX STK38 TUBGCP3 AIF1 WDFY3

2.43e-041961166M5349
CoexpressionGSE3982_MAC_VS_EFF_MEMORY_CD4_TCELL_DN

KIF21B SYNE1 FXR1 DDX50 COQ8A SRPX

2.43e-041961166M5504
CoexpressionGSE19888_ADENOSINE_A3R_INH_VS_INH_PRETREAT_AND_ACT_WITH_TCELL_MEMBRANES_MAST_CELL_DN

WDR64 KCNIP1 NWD2 PTPRN2 PPP1R36 EPCAM

2.50e-041971166M7345
CoexpressionGSE20152_SPHK1_KO_VS_HTNFA_OVEREXPRESS_ANKLE_DN

REXO4 CYP2E1 SYNE1 PIK3R3 SSRP1 DCLRE1A

2.50e-041971166M7683
CoexpressionDAIRKEE_CANCER_PRONE_RESPONSE_E2

ABCC4 MYOM2 CNR1

2.55e-04281163M6041
CoexpressionGSE43863_DAY6_EFF_VS_DAY150_MEM_TFH_CD4_TCELL_DN

WDR64 RNF144A SUV39H2 TENM4 AIF1 ENDOU

2.57e-041981166M9747
CoexpressionGSE22886_TCELL_VS_BCELL_NAIVE_DN

ABCA1 FBLN1 SLC9A7 PIP5K1B CNR1 PHLPP2

2.57e-041981166M4426
CoexpressionGSE40666_UNTREATED_VS_IFNA_STIM_CD8_TCELL_90MIN_DN

UBA5 ATR EFTUD2 PIGH UTP11 MRPL24

2.64e-041991166M9227
CoexpressionGSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN

POLR2A PIK3R3 LRRK2 COQ8A PREX1 PHLPP2

2.71e-042001166M4667
CoexpressionGSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_DN

HK2 RNF144A IGF1R GUCY1A1 CDH1 TARBP1

2.71e-042001166M8033
CoexpressionGSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_DN

ABCC4 ABCA1 HK2 CYP2E1 RNF144A IGF1R

2.71e-042001166M8027
CoexpressionGSE10240_CTRL_VS_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP

ABCA1 KIF21A RNF144A ITPR1 IGF1R PLCL1

2.71e-042001166M302
CoexpressionGSE27786_BCELL_VS_NKCELL_UP

IFT140 WDR64 LRRK2 WDR3 CNR1 PDE11A

2.71e-042001166M4805
CoexpressionGSE557_CIITA_KO_VS_I_AB_KO_DC_DN

DTNA C19orf47 NELFB SSRP1 FABP5 TOP2B

2.71e-042001166M6014
CoexpressionGSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_DN

KIF21B SYNE1 STK38 MRPL24 PREX1 NIPBL

2.71e-042001166M7441
CoexpressionGSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_UP

CFAP47 ABCC4 RNF144A GPR174 NAA30 NIPBL

2.71e-042001166M5087
CoexpressionGSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_12H_UP

DOCK4 DYNLT2B CCDC186 GSTA3 THBS1 TENM4

2.71e-042001166M6418
CoexpressionGSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP

IFT140 RNF144A STK38 IGF1R COQ8A NIPBL

2.71e-042001166M6477
CoexpressionGSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_DN

DYNLT2B RNF144A POLR2A SKIL IGF1R IFIT1B

2.71e-042001166M5271
CoexpressionGSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_45MIN_UP

DOCK4 RAPSN ATRX USP9X FXR1 WDFY3

2.71e-042001166M6629
CoexpressionGSE5679_CTRL_VS_RARA_AGONIST_AM580_TREATED_DC_DN

SLC25A24 ATRX UNC45A SKIL PIGH PLCL1

2.71e-042001166M6556
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBGABA

DOCK4 KIF21B GAD2 KIF21A DICER1 TENM4 GUCY1A1 SLC9A7 TARBP1 CNR1 PDE11A

2.93e-0470311611M39070
CoexpressionSWEET_LUNG_CANCER_KRAS_UP

HK2 CCDC186 TOM1L1 THBS1 SERPINE2 SCG3 PIP5K1B ATP11A EPCAM

3.08e-044841169M19097
CoexpressionSOBOLEV_PBMC_PANDEMRIX_AGE_18_64YO_CORRELATED_WITH_AGE_1DY_POSITIVE

DOCK4 KIF21B SYNE1

3.14e-04301163M41011
CoexpressionFAN_EMBRYONIC_CTX_BIG_GROUPS_GLIAL

MYO10 DTNA FABP5 LYPD1 SERPINE2

3.19e-041331165M39020
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2A

CFAP47 DTNA LRRK2 KCNIP1 FABP5 FAT1 LYPD1 SERPINE2 SCG3 PREX1

3.40e-0460011610M39055
CoexpressionSIMBULAN_UV_RESPONSE_IMMORTALIZED_DN

THBS1 IGF1R TOP2B

3.47e-04311163M3732
CoexpressionKYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION

POLR2A CDCA7 ENDOU PLCL1

3.84e-04771164M2540
CoexpressionAtlasECTO blastocyst_vs_ECTO amniotic fluid MSC-Confounder_removed-fold2.0_adjp0.05

POLA1 FABP5 FBLN1 LYPD1 TENM4 CDCA7 CDH1 EPCAM PREX1

1.91e-052801139PCBC_ratio_ECTO blastocyst_vs_ECTO amniotic fluid MSC_cfr-2X-p05
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

ABCC4 LRRK2 GSTA3 FAT1 PIP5K1B ATP11A RP1

2.27e-071631157e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN1 THBS1 SERPINE2 NWD2 GUCY1A1 SRPX PLCL1

3.97e-071771157bd602db857f37869ef76d14c05ef522c509f08ee
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 KIF21A LRRK2 TENM4 ATP11A CDH1 EPCAM

5.15e-071841157ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCC4 TOM1L1 LRRK2 FAT1 RP1 PLCL1 CDH1

5.34e-07185115798b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 KIF21A LRRK2 FAT1 IGF1R ATP11A WDFY3

5.75e-0718711579d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

DTNA KIF21A COQ8A XIRP2 PIP5K1B MYOM2 PLCL1

5.75e-07187115778cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

DOCK4 MYO10 SYNE1 PIK3R3 FAT1 PIP5K1B PREX1

6.39e-0719011577f3f419fffe02934b6f27b697f7a6401072491ed
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX RASA2 CCDC186 PRPF40A CDH1 EPCAM TOP2B

6.62e-07191115709db184cb90fe282a14474d7217068c58092c6f8
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 DNAH10 SYNE1 LRRK2 GSTA3 ATP11A RP1

7.10e-071931157bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 ATRX MYO10 USP9X KIF21A PTPRN2 SCG3

7.61e-0719511577796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 ATRX CCDC186 THBS1 SERPINE2 GUCY1A1 MYBPC2

7.61e-0719511575c86fddd6d0530beecf45ea5ba6b823123847696
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 SKIL FBLN1 THBS1 SERPINE2 SRPX CNR1

7.88e-07196115761bee32ca299219f31a30b57124e44e85b798e9f
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

ABCC4 KIF21A LRRK2 FAT1 ATP11A CDH1 EPCAM

8.15e-07197115744a59dfb889577b3160a5b13ada1276771a00241
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ABCC4 KIF21A LRRK2 FAT1 ATP11A CDH1 EPCAM

8.43e-071981157285f729140b1df029c24f6ca1d2438470ac51794
ToppCellBiopsy_Other_PF-Epithelial-AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type

SYNE1 LRRK2 ATP11A CDH1 EPCAM TCF7L1 CNR1

8.72e-0719911579a65acfe9bf500db72142469cf17bf0973540001
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCC4 SYNE1 LRRK2 GUCY1A1 PIP5K1B ATP11A CNR1

8.72e-0719911572dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ABCC4 KIF21A LRRK2 FAT1 ATP11A CDH1 EPCAM

9.02e-072001157e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Interneuron|10w / Sample Type, Dataset, Time_group, and Cell type.

RPL21 KIF21B GAD2 GRIN2B LYPD1 SCG3 EPCAM

9.02e-072001157f5c63ef52bd7a898cf009b8bf9b2f7f4890d1c9b
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD2 MYH13 KCNIP1 PIP5K1B CNR1 PDE11A

1.13e-06130115660e28d452d0e2af768459ba8dbe998117c94a251
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD2 KCNIP1 FAT1 PIP5K1B CNR1 PDE11A

2.80e-061521156fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD2 KCNIP1 FAT1 PIP5K1B CNR1 PDE11A

3.37e-061571156516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

ABCC4 LRRK2 GSTA3 FAT1 PIP5K1B RP1

3.37e-06157115631d1bd9138c60e8485664ec4144f987226e3eef9
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

LRRK2 FABP5 SLC26A7 GSTA5 CDH1 CNR1

4.34e-061641156beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

LRRK2 FABP5 SLC26A7 GSTA5 CDH1 CNR1

4.34e-061641156d005cfd821b87548b075120bffe65a0be9860463
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A24 RASA2 SYNE1 LRRK2 THBS1 IGF1R

5.70e-061721156d354424c1f861b6607dfd63b9724f4c237b30275
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT2|E18.5-samps / Age Group, Lineage, Cell class and subclass

HK2 LRRK2 FABP5 ATP11A CDH1 EPCAM

5.89e-061731156f6e36ea98a9c669ff393d141455aaecef083f738
ToppCellP28-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRRK2 FABP5 PIP5K1B ATP11A CDH1 EPCAM

6.30e-0617511568a4ed775ff973123dbcfe9c809959d11a62450c9
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

ABCC4 GSTA3 FAT1 PIP5K1B RP1 PLCL1

6.50e-0617611563fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT2|PND01-03-samps / Age Group, Lineage, Cell class and subclass

LRRK2 FABP5 PIP5K1B ATP11A CDH1 EPCAM

6.50e-061761156ac76f2cd6c63f30b38b89b58bad2baa4dde8ce3a
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYO10 GUCY1A1 SLC9A7 PLCL1 PPP1R36 CDH1

6.72e-0617711563a150dcaefa342d49968b42c7cdb1fbb633adcd0
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPSN PEPD GSTA3 SERPINE2 IGF1R CDH1

6.72e-0617711569b4c1ca5c6fca9a7a936dad49a04155903ef9c32
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MYO10 GUCY1A1 SLC9A7 PLCL1 PPP1R36 CDH1

6.72e-061771156c9e5820ff0bc7ad1adcfb2651713fdfc58bced56
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 KIF21A LRRK2 TENM4 ATP11A CDH1

7.16e-061791156fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

ABCC4 SYNE1 LRRK2 PIP5K1B ATP11A TCF7L1

7.40e-061801156198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 KIF21A LRRK2 TENM4 CDH1 EPCAM

7.63e-0618111560513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 KIF21A TENM4 ATP11A CDH1 EPCAM

7.88e-06182115617ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 KIF21A LRRK2 TENM4 CDH1 EPCAM

8.13e-061831156e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Endothelial_Tip.Dcn.Dapl1_(Dapl1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC26A7 XIRP2 MYOM2 CDH1 MYBPC2

8.24e-0610611557079111add27d7b3411dfe739280d62dc256a174
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Endothelial_Tip.Dcn.Dapl1_(Dapl1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC26A7 XIRP2 MYOM2 CDH1 MYBPC2

8.24e-061061155a6334b67be05f78145b57271b7959471b80bd67f
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

ABCC4 KIF21A LRRK2 FAT1 SERPINE2 PLCL1

8.38e-06184115651ed1ebfdef45149541917c66cbacad87072e51f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 GRIN2B FAT1 TENM4 XIRP2 MYOM2

8.38e-0618411562cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 GRIN2B FAT1 TENM4 XIRP2 MYOM2

8.38e-061841156ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 GRIN2B FAT1 TENM4 XIRP2 MYOM2

8.38e-0618411562b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 KIF21A TENM4 ATP11A CDH1 EPCAM

8.38e-061841156d0c212a8fbaad24597a84018442b25c61c17ea58
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF21A LRRK2 PIP5K1B ATP11A CDH1 EPCAM

8.65e-0618511560d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 KIF21A LRRK2 TENM4 ATP11A CDH1

8.92e-061861156e83718fabb057100835d3357df407f283d23fe16
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

ABCC4 TOM1L1 LRRK2 RP1 PLCL1 CDH1

9.19e-06187115681cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

ABCC4 DTNA KIF21A PEPD FAT1 SERPINE2

9.19e-061871156d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 SYNE1 RNF144A KCNIP1 PIP5K1B PLCL1

9.19e-06187115615d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 SYNE1 RNF144A KCNIP1 PIP5K1B PLCL1

9.19e-061871156f62074b631fd45ad299c69d71b09267b04d656ee
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 SYNE1 RNF144A KCNIP1 PIP5K1B PLCL1

9.48e-06188115632f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 ATRX KIF21A PRPF40A SERPINE2 NIPBL

9.48e-061881156d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 KIF21A LRRK2 TENM4 ATP11A CDH1

9.48e-0618811564bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellfacs-Heart-RA-24m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP2E1 GSTA3 FBLN1 SERPINE2 MYOM2 SRPX

9.77e-061891156e4efbb0733b382f4c855f6653dcddf36e0f8df28
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 DTNA KIF21A LRRK2 FAT1 ATP11A

9.77e-0618911563b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX RASA2 CCDC186 PRPF40A CDH1 TOP2B

1.04e-05191115660c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 DTNA LRRK2 KCNIP1 FAT1 ATP11A

1.04e-0519111561cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX RASA2 CCDC186 PRPF40A CDH1 TOP2B

1.04e-051911156973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellwk_20-22-Epithelial-Distal_epithelial_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ABCC4 TOM1L1 CDCA7 ATP11A CDH1 EPCAM

1.07e-051921156fa2420d6117d4800f60ef6a24bcf8bf54593cd1f
ToppCellwk_20-22-Epithelial-Distal_epithelial_progenitor-epi-tip_late|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ABCC4 TOM1L1 CDCA7 ATP11A CDH1 EPCAM

1.07e-05192115687b60014202633a4f6d19b09a5dd9276c2edecfb
ToppCellMonocytes-Tissue-resident_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

DOCK4 ABCC4 HK2 DTNA SDCCAG8 SKIL

1.10e-051931156198552810dcac8d0ca63a78badd6702b49ff6edf
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCC4 SYNE1 LRRK2 PIP5K1B ATP11A TCF7L1

1.10e-051931156fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCC4 SYNE1 LRRK2 PIP5K1B ATP11A TCF7L1

1.10e-051931156f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 PIK3R3 KCNIP1 FAT1 CDCA7 PIP5K1B

1.13e-05194115652aebb0b563e2c2058e7f0554ae870e47692b163
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 PIK3R3 KCNIP1 FAT1 CDCA7 PIP5K1B

1.13e-051941156bd06e2b8d8c06cddf2e4f58849b86e09013acae1
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCC4 SYNE1 LRRK2 PIP5K1B ATP11A CDH1

1.13e-05194115697534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellControl-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

ABCC4 LRRK2 FABP5 PIP5K1B ATP11A TCF7L1

1.13e-051941156a01de094f7bfd099bcbb2f94224690a2efb887b4
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

RAPSN KIF21A FBLN1 FAT1 TENM4 SRPX

1.17e-051951156ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 ATRX USP9X KIF21A PTPRN2 SCG3

1.17e-0519511563e519cffa6144a62b06124642a14c9ff39b76554
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 DNAH10 SYNE1 KIF21A RP1 PPP1R36

1.24e-05197115691637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 DNAH10 SYNE1 KIF21A RP1 PPP1R36

1.24e-05197115622c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ABCC4 KIF21A LRRK2 ATP11A CDH1 EPCAM

1.24e-0519711561485933986921ff45669d9b7501c8d17050b3e97
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 DNAH10 SYNE1 KIF21A RP1 PPP1R36

1.24e-0519711563bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

ABCC4 KIF21A LRRK2 ATP11A CDH1 EPCAM

1.24e-0519711561a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 DNAH10 SYNE1 KIF21A RP1 PPP1R36

1.24e-05197115687db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellControl_saline-Epithelial_alveolar-AT_2|Control_saline / Treatment groups by lineage, cell group, cell type

ABCC4 KIF21A GSTA3 ATP11A CDH1 EPCAM

1.24e-051971156b8f62fcd6eb8f47b3cc41f616126f82c68a36e87
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ABCC4 KIF21A LRRK2 ATP11A CDH1 EPCAM

1.24e-0519711561638959d7aecb9fc5285eb7e4a3103ca437989e2
ToppCellControl_saline-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor|Control_saline / Treatment groups by lineage, cell group, cell type

ABCC4 KIF21A GSTA3 ATP11A CDH1 EPCAM

1.27e-051981156030ef63e2fc5b3d601c1a48462d797aa19ee7ff5
ToppCellB_cell_maturation-CD34+_pro-B|B_cell_maturation / Lineage and Cell class

DYNLT2B SSRP1 FABP5 CDCA7 AIF1 TOP2B

1.27e-0519811565737606e5e3dc56f11fdf70166caf4ba4a81bc9d
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DTNA KIF21A FABP5 LYPD1 SRPX CNR1

1.27e-05198115681c4c5377d0901ee9594424f08b0e4101686c850
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC4 SDCCAG8 LRRK2 PIP5K1B ATP11A TCF7L1

1.27e-0519811562e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ABCC4 KIF21A LRRK2 ATP11A CDH1 EPCAM

1.27e-051981156c4e7512f0e1d115f2be8acae6048eda8b6b640b2
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ABCC4 KIF21A LRRK2 ATP11A CDH1 EPCAM

1.27e-051981156aa80315395cb5dffc25927c8a77cd2037aea8772
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRRK2 PIP5K1B ATP11A CDH1 EPCAM CNR1

1.31e-051991156a38a981cffa61c8444a980916de7414e689a1b63
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DOCK4 MYO10 SYNE1 FBLN1 THBS1 SRPX

1.31e-05199115630d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

ABCA1 PIK3R3 FABP5 FBLN1 THBS1 CNR1

1.35e-052001156fd6b4ff4330db11c03f1eb4e06b43a162326f744
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Macroglial-Astrocyte|GW26 / Sample Type, Dataset, Time_group, and Cell type.

MYO10 FABP5 FAT1 LYPD1 SERPINE2 PREX1

1.35e-052001156158ba898312c73bcb54c675a4860874a1dd58662
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

ABCA1 PIK3R3 FABP5 FBLN1 THBS1 CNR1

1.35e-0520011568795920911ee75c09a97cc948c14ad7301b27796
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRRK2 PIP5K1B ATP11A CDH1 EPCAM CNR1

1.35e-052001156b535323e18d9fb0dde1e0026df142c831e48c29f
ToppCell10x_3'_v2v3-Neoplastic|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYO10 DTNA KIF21A LYPD1 SERPINE2 SCG3

1.35e-052001156e9c7d7cb5fa63fc92aa91d02ae8bd05438d465bc
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Macroglial|GW26 / Sample Type, Dataset, Time_group, and Cell type.

MYO10 FABP5 FAT1 LYPD1 SERPINE2 PREX1

1.35e-05200115646f99bed98da09e6d3f45d4443cbaa6b6c1589bb
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Car10|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD2 FAT1 PIP5K1B PLCL1 CNR1

1.98e-051271155f808c727c0817ed10e76eaffa9493a516e9a6b50
ToppCellfacs-Thymus-Epithelium-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTNA TOM1L1 SUV39H2 PIP5K1B ENDOU

2.39e-0513211556f711fe84135406a8114a898a14c5ea0dfad74f2
ToppCellCOVID-19-Mast_cells-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

KIF21B KCNIP1 SLC8A3 GPR174 DCLRE1A

3.28e-0514111550fc06c2325249aa4ae65c0ace1ec3f953372f2e4
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 GSTA3 NWD2 ATP11A EPCAM

3.74e-0514511559b69bfdbf91ef197b4c483617aa67498d9d2cd79
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 GSTA3 NWD2 ATP11A EPCAM

3.74e-05145115531af9fce1dcd7e8ae1604476598e099232017ee9
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 GSTA3 NWD2 ATP11A EPCAM

3.74e-05145115576f0cde9acdc3ad5948c007dccf312665972c9e6
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RPL21 KCNIP1 GUCY1A1 IFIT1B AIF1

4.26e-05149115558c1ac5a46898021224b9cb1483a0c58554bc4fb
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

GAD2 GRIN2B CABYR CDH1 CNR1

4.26e-0514911556e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

CFAP47 DNAH10 PTPRN2 RP1 EPCAM

4.54e-0515111558216462e723fec2797387929dde095370947e10a
Drug8-ethoxycaffeine

SDCCAG8 DICER1 FBLN1 THBS1 FXR1 CDH1 EPCAM

1.63e-061111167CID000011347
Druggeldanamicin

GAD2 HK2 CYP2E1 POLA1 PIK3R3 TOM1L1 PRPF40A THBS1 IGF1R MYOM2 CNR1

3.33e-0637311611CID000003460
Drugdimethyl phthalate

ABCC4 HK2 ATR MYO10 PIK3R3 PEPD STK38 PSMC5 SKIL DICER1 ITPR1 TUBGCP3 GAN PIP5K1B TOP2B

3.52e-0671411615ctd:C024629
DrugYohimbine hydrochloride [65-19-0]; Up 200; 10.2uM; MCF7; HT_HG-U133A

MYO10 POLR2A GRIN2B KCNIP1 FBLN1 THBS1 SLC9A7 ATP11A

8.09e-0619811686777_UP
DrugV0509

HK2 FXR2 PIK3R3 PRPF40A DICER1 FXR1 IGF1R RP1 CNR1

1.09e-052721169CID000102191
Drugbenzoquinone

CYP2E1 POLA1 SYNE1 GRIN2B PRPF40A COQ8A TOP2B CNR1

1.20e-052091168CID000004650
Drugimidazole

CYP2E1 GSTA3 GSTA5

1.51e-05101163ctd:C029899
Drugaflatoxin B1-2,3-oxide

CYP2E1 GSTA3 GSTA5

1.51e-05101163ctd:C006426
DrugAC1NSWD2

SYNE1 TOP2B

2.57e-0521162CID005318091
Diseasefragile X syndrome (implicated_via_orthology)

FXR2 FXR1

4.20e-0531112DOID:14261 (implicated_via_orthology)
Diseasemalignant pleural mesothelioma (implicated_via_orthology)

FXR2 FXR1

4.20e-0531112DOID:7474 (implicated_via_orthology)
Diseasefetal alcohol spectrum disorder (biomarker_via_orthology)

GRIN2B IGF1R

8.37e-0541112DOID:0050696 (biomarker_via_orthology)
DiseaseSchizophrenia

DOCK4 GAD2 ABCA1 CYP2E1 SDCCAG8 GRIN2B DICER1 FABP5 THBS1 TENM4 SLC26A7 CNR1

1.25e-0488311112C0036341
Diseaseplatelet component distribution width

RAPSN MYH13 SYNE1 SDCCAG8 LRRK2 STK38 IGF1R AIF1 PIP5K1B PREX1 TCF7L1

1.33e-0475511111EFO_0007984
DiseaseParkinson Disease

CYP2E1 LRRK2 IGF1R AIF1

3.04e-04851114C0030567
DiseaseEndometrioma

ABCC4 LRRK2 DICER1 FBLN1 CNR1

3.66e-041611115C0269102
DiseaseEndometriosis

ABCC4 LRRK2 DICER1 FBLN1 CNR1

3.66e-041611115C0014175
Diseasetype 1 diabetes mellitus (implicated_via_orthology)

GAD2 PTPRN2 AIF1

4.29e-04391113DOID:9744 (implicated_via_orthology)
DiseaseAlzheimer's disease (is_marker_for)

ATR GRIN2B ITPR1 SLC8A3 IGF1R AIF1

4.35e-042571116DOID:10652 (is_marker_for)
Diseasehigh grade glioma (is_implicated_in)

ATRX CYP2E1 IGF1R

5.34e-04421113DOID:3070 (is_implicated_in)
Diseaseobsolete_red blood cell distribution width

RAPSN ATR FXR2 DIPK1A C19orf47 PEPD CCNF IGF1R CDCA7 RNASEH2C ATP11A RP1 PPP1R36 CDH1

5.36e-04134711114EFO_0005192
DiseaseAdenoid Cystic Carcinoma

ATRX FAT1 GUCY1A1 CDH1

5.63e-041001114C0010606
DiseasePancreatic Neoplasm

ATRX CDH1 EPCAM CNR1

5.63e-041001114C0030297
DiseaseMalignant neoplasm of pancreas

ATRX CDH1 EPCAM CNR1

6.07e-041021114C0346647
DiseaseThyroid carcinoma

DICER1 CDH1 TCF7L1

6.13e-04441113C0549473
Diseasehepatocellular carcinoma (is_implicated_in)

CYP2E1 DICER1 EFTUD2 IGF1R CDH1

6.23e-041811115DOID:684 (is_implicated_in)
DiseaseColorectal Neoplasms

ABCC4 ABCA1 SYNE1 CABYR FAT1 CDH1

6.44e-042771116C0009404
DiseaseMalignant neoplasm of salivary gland

FAT1 GUCY1A1 CDH1

6.55e-04451113C0220636
DiseaseSalivary Gland Neoplasms

FAT1 GUCY1A1 CDH1

7.45e-04471113C0036095
DiseaseProstatic Intraepithelial Neoplasias

CDH1 TOP2B

7.54e-04111112C0282612
DiseaseDiabetic Retinopathy

GAD2 THBS1

7.54e-04111112C0011884
Diseaselevel of Sterol ester (27:1/20:5) in blood serum

RAPSN NWD2

7.54e-04111112OBA_2045197
Diseasemyopathy (implicated_via_orthology)

MYH13 PSMC5 MYBPC2

7.92e-04481113DOID:423 (implicated_via_orthology)
Diseasemyeloid white cell count

SLC25A24 GAD2 RAPSN RASA2 DNAH10 PIK3R3 PEPD GUCY1A1 RP1 PREX1 TCF7L1

8.23e-0493711111EFO_0007988
Diseasemean reticulocyte volume

RAPSN ATR RASA2 DIPK1A C19orf47 PEPD STK38 CDCA7 SCG3 PREX1

8.83e-0479911110EFO_0010701
Diseaseprogression free survival, urinary bladder cancer

IFT140 TENM4

9.03e-04121112EFO_0004920, MONDO_0001187
DiseaseShort Rib-Polydactyly Syndrome

DYNLT2B IFT140

1.06e-03131112C0036996
Diseasemale infertility (implicated_via_orthology)

CFAP47 CABYR

1.06e-03131112DOID:12336 (implicated_via_orthology)
DiseasePeripheral Nervous System Diseases

ABCA1 IGF1R GAN

1.12e-03541113C4721453
DiseaseSaldino-Noonan Syndrome

DYNLT2B IFT140

1.24e-03141112C0036069
DiseaseMajewski Syndrome

DYNLT2B IFT140

1.24e-03141112C0024507
Diseasediabetic neuropathy (implicated_via_orthology)

IGF1R CNR1

1.24e-03141112DOID:9743 (implicated_via_orthology)
Diseasepolyp of colon

RAPSN CDH1 PREX1

1.24e-03561113MONDO_0021400
Diseaseplatelet measurement

ABCC4 RAPSN LRRK2 STK38 SLC8A3 SERPINE2

1.25e-033151116EFO_0005036
Diseaseneutrophil count, eosinophil count

SLC25A24 RAPSN RASA2 PIK3R3 COQ8A

1.29e-032131115EFO_0004833, EFO_0004842
DiseaseRhabdomyosarcoma

DICER1 CNR1

1.43e-03151112C0035412
DiseaseBenign neoplasm of stomach

ATR CDH1

1.84e-03171112C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ATR CDH1

1.84e-03171112C0496905
Diseaseextrahepatic cholestasis (biomarker_via_orthology)

ABCC4 ABCA1

1.84e-03171112DOID:13619 (biomarker_via_orthology)
DiseaseCarcinoma in situ of stomach

ATR CDH1

1.84e-03171112C0154060
Diseasemethylcobalamin deficiency type cblE, overall survival, ovarian carcinoma, response to cisplatin

RASA2 FABP5

1.84e-03171112EFO_0000638, EFO_0001075, GO_0072718, MONDO_0009354
Diseasecolorectal cancer

ABCC4 RAPSN UNC45A PTPRN2 DCLRE1A PLCL1 CDH1 PREX1

2.05e-036041118MONDO_0005575
Diseaselevel of Phosphatidylcholine (20:4_0:0) in blood serum

RAPSN TCF7L1

2.06e-03181112OBA_2045110
DiseaseBMI-adjusted waist-hip ratio, physical activity measurement

ABCA1 DNAH10 PEPD

2.27e-03691113EFO_0007788, EFO_0008002
Diseasefamilial hyperlipidemia (biomarker_via_orthology)

ABCA1 CYP2E1

2.30e-03191112DOID:1168 (biomarker_via_orthology)
DiseaseProstatic Neoplasms

ABCC4 ATR CYP2E1 TOM1L1 ITPR1 FBLN1 CDH1 EPCAM

2.32e-036161118C0033578
DiseaseMalignant neoplasm of prostate

ABCC4 ATR CYP2E1 TOM1L1 ITPR1 FBLN1 CDH1 EPCAM

2.32e-036161118C0376358
Diseaseobesity (biomarker_via_orthology)

ABCA1 HK2 CYP2E1 IGF1R

2.34e-031471114DOID:9970 (biomarker_via_orthology)
DiseaseMalignant neoplasm of breast

SYNE1 MAGOHB SUV39H2 THBS1 SLC8A3 SERPINE2 FXR1 IGF1R CDH1 NIPBL TCF7L1

2.43e-03107411111C0006142
DiseaseEndometrial Carcinoma

ATR IGF1R CDH1

2.56e-03721113C0476089
Diseaseautism spectrum disorder (implicated_via_orthology)

FXR2 FXR1 WDFY3 PREX1

2.64e-031521114DOID:0060041 (implicated_via_orthology)
DiseasePR interval

DOCK4 RAPSN DTNA THBS1 FAT1 COQ8A CNR1

2.72e-034951117EFO_0004462
DiseaseS-6-hydroxywarfarin measurement

DTNA TOM1L1 FBLN1 UCHL5 MYOM2 PLCL1

2.73e-033681116EFO_0803326
Diseasetriglyceride measurement, body fat percentage

DNAH10 PEPD

2.81e-03211112EFO_0004530, EFO_0007800
DiseaseStomach Carcinoma

ATR CDH1

2.81e-03211112C0699791
Diseaselevel of Phosphatidylcholine (18:1_20:4) in blood serum

ABCA1 RAPSN

2.81e-03211112OBA_2045104
Diseaseprostate cancer (is_marker_for)

FABP5 IGF1R CDH1 PREX1

2.90e-031561114DOID:10283 (is_marker_for)
Diseaseblood pressure

SYNE1 PREX1

3.08e-03221112EFO_0004325
DiseaseLewy Body Disease

IGF1R AIF1

3.08e-03221112C0752347
Diseaseplatelet crit

ABCC4 RAPSN MYH13 ATRX DIPK1A LRRK2 THBS1 IGF1R RP1 PREX1

3.19e-0395211110EFO_0007985
Diseaseschizophrenia (is_implicated_in)

GAD2 GRIN2B CNR1

3.21e-03781113DOID:5419 (is_implicated_in)
Diseasecancer (implicated_via_orthology)

PSMC5 SSRP1 PIP5K1B NIPBL TOP2B

3.49e-032681115DOID:162 (implicated_via_orthology)
Diseasenephrotic syndrome (implicated_via_orthology)

FAT1 COQ8A

3.67e-03241112DOID:1184 (implicated_via_orthology)
Diseaselymphocyte percentage of leukocytes

GAD2 RAPSN PIK3R3 C19orf47 COQ8A SLC9A7 PREX1 TCF7L1

3.69e-036651118EFO_0007993

Protein segments in the cluster

PeptideGeneStartEntry
SYVGEVVRAMDKKKV

PSMC5

71

P62195
KYEKAEIKEMGEMHR

EPCAM

296

P16422
MVMKYVRGEKESLDL

CCDC186

311

Q7Z3E2
RRVTAEMEGKYVINM

C19orf47

201

Q8N9M1
YEKEARLKETMRIMG

ABCA1

661

O95477
LKEKVVLMYDEIFMT

ARMH3

21

Q5T2E6
MYRGNTTMDIKDLVK

CABYR

46

O75952
VAGMMVRELQKYIKH

DICER1

321

Q9UPY3
AEMTDQYMAVKGIKR

BMS1

471

Q14692
IERFVKIPEMGKYMD

NWD2

266

Q9ULI1
IVLKEETRMLGLMYA

LINC00301

6

Q8NCQ3
HREVMKAVKVGMKEY

PEPD

206

P12955
MGRYKEMLKFAVVQI

RAPSN

56

Q13702
LDEMMKIVGGHYLKV

RASA2

406

Q15283
RMVVMHGYKAVKEAL

CYP2E1

76

P05181
MKERALIDMYTEGIV

GSTA5

86

Q7RTV2
RSGTYVLIDMVLNKM

PTPRN2

951

Q92932
KLYEMEILAADRGMK

FAT1

216

Q14517
LSKVAPVIKARMMEY

GAD2

526

Q05329
LARVRMMKGDFYVIE

FXR2

91

P51116
MMTKDRGYGEKLISI

ITPR1

1691

Q14643
LAKVRMMKGEFYVIE

FXR1

81

P51114
YMGELVRLILVKMAK

HK2

301

P52789
IKERALIDMYTEGMA

GSTA3

86

Q16772
LVIMELMTRGDLKSY

IGF1R

1076

P08069
LFEDYLMRKGKQEMV

PDE11A

21

Q9HCR9
MGIIDILQSYRLMKK

PIP5K1B

346

O14986
LREIMKTAVMKELYS

ENDOU

231

P21128
QMELMEYKAGKRVIG

KIF21B

396

O75037
EDLMKLIIKYGMTVV

NIPBL

2071

Q6KC79
VVDVAKLMKAYISMI

MYO10

2026

Q9HD67
RMVGKNVKLYDMVLQ

NELFB

206

Q8WX92
RMVIRYQMKSAVEEG

LRRK2

841

Q5S007
GDKIMALKMELAYLR

LURAP1

56

Q96LR2
GRTKKQLAMVMRYGV

SERPINE2

71

P07093
KRMEYILTDIRKGHM

TUBGCP3

671

Q96CW5
GYMKETKRAVIFMIN

GPR174

46

Q9BXC1
VTYKGREILMHTKEM

POLA1

976

P09884
EYMKELGVGIALRKM

FABP5

21

Q01469
VMFYGRKIMRKVTTL

PNPLA7

56

Q6ZV29
GYINKEEMMDIVKAI

KCNIP1

151

Q9NZI2
IECMVAAEIMQRYKK

RNF144A

81

P50876
TRYKKAEQMFGEMEV

PRPF40A

481

O75400
MNEVITGIRIIKMYA

ABCC4

276

O15439
DIIKRYMDGMTVGVV

FBLN1

646

P23142
IMMNYDKLKSRLGEI

PIK3R3

256

Q92569
DVRVMKKRAHILYEM

ATRX

1796

P46100
EKGVYMTGKELRQCM

ATR

2396

Q13535
TGNTQVEYMIRIMKK

TTC26

531

A0AVF1
KKVLEKYGDMRVTMG

DOCK4

1031

Q8N1I0
KYEDLVRMMGEIVSA

CCNF

386

P41002
YKIELEGISVMVMRE

GAN

71

Q9H2C0
KTIMLKRTFEMAYVD

IFIT1B

331

Q5T764
MKSRYEQVDLVGKMT

DDX50

341

Q9BQ39
SIEMKFLTGYEVKVM

COQ8A

541

Q8NI60
AIMVYDVFGKMNKLI

CNR1

361

P21554
KEVMEQSAGIMYRKS

LYPD1

56

Q8N2G4
GGKIMDKLRYIFSMI

DTNA

141

Q9Y4J8
TKVMKQMDIGVYFGL

DCLRE1A

551

Q6PJP8
YDLKMVDMRKIVPET

DIPK1A

306

Q5T7M9
KVQKEMSGLRMIYEL

DNAH10

1256

Q8IVF4
GEKVMLDIVAMFRQY

S100A7L2

6

Q5SY68
MIEKSYDIMAKRITF

CFAP47

2981

Q6ZTR5
EKGVQMDRAVMLYHK

IFT140

1076

Q96RY7
LKEMGFDRYKMVVQV

DYNLT2B

81

Q8WW35
MALEVGDYKINLKLM

CDH1

656

P12830
SKNIMEEKRMNGIIY

RP1

1511

P56715
VMIRKEAYVHKSVME

MAGOHB

46

Q96A72
DAQAAMRLYVMVKKE

REXO4

386

Q9GZR2
LMRTQDVKYIEMKRV

UTP11

96

Q9Y3A2
EGKLVAKRRAYMMDD

USP9X

751

Q93008
TGHVYAMKILRKADM

STK38

111

Q15208
KLYKTGREMQERIMD

TOM1L1

241

O75674
AESLKTLRYGKIMIM

TOP2B

546

Q02880
DKGKIMEEVMRTYLK

SKIL

526

P12757
MDRMKKEYTDCVVTL

SYNE1

706

Q8NF91
EITKEREYMGSKMLI

SDCCAG8

396

Q86SQ7
SLKLGMERDAYVMIA

PREX1

396

Q8TCU6
MERDAYVMIAEKGEK

PREX1

401

Q8TCU6
MVLVDKHGMDKERYV

SRPX

416

P78539
EEVMEAMGIKETRKY

MRPL24

196

Q96A35
YEMVSRVMKALVNRK

SSRP1

311

Q08945
LGKRSAILKMILMYE

AIF1

111

P55008
AILKMILMYEEKARE

AIF1

116

P55008
MLVRKRKTVDGYMNE

CDCA7

206

Q9BWT1
KIFGVAIYTGMETKM

ATP11A

261

P98196
EIGDVRMAKYKLMNQ

XIRP2

1401

A4UGR9
MAIVSDRKMIYEQKI

UCHL5

221

Q9Y5K5
LSVRMGKKVREYTML

PLCL1

861

Q15111
IRVVMYEGKKIMADS

THBS1

1121

P07996
EQVGMIKEKYEHRML

TTBK1

246

Q5TCY1
KEMERIKGYQLLAML

WDFY3

1446

Q8IZQ1
VYEKLTMLDRVVMAG

PHLPP2

386

Q6ZVD8
YMKEMRAKVVAECTL

TCF7L1

356

Q9HCS4
LQMELMEYKTGKRII

KIF21A

396

Q7Z4S6
LMALKRMGIVSDYEK

UBA5

56

Q9GZZ9
IKRMSFVMEYVGEVI

SUV39H2

271

Q9H5I1
KSMESVMVKYDATVR

POLR2A

866

P24928
GYVMVTEEKKVSMGK

RNASEH2C

81

Q8TDP1
MYVKGMIQTRENDKV

MYH13

46

Q9UKX3
MGKVKDIVINEAIYM

PIGH

116

Q14442
MRIYKKGDIVDIKGM

RPL21

31

P46778
MTVQYDNMGRVVKKE

TENM4

2166

Q6N022
YMVGLVEKKEMELVL

PPP1R36

176

Q96LQ0
IMYKIIEMSAIKTGV

TARBP1

1021

Q13395
MEAIELYREETAKMK

WDR3

761

Q9UNX4
MHDLRKMYSEIDIKV

EFTUD2

641

Q15029
YGVVKLMKIMGQLSD

SLC9A7

231

Q96T83
GVSMLVEVYMDCKGR

SLC26A7

586

Q8TE54
LIDFVKMMVKYGTIS

SCG3

306

Q8WXD2
IYPMEVMKTRLAVGK

SLC25A24

306

Q6NUK1
ILKEKAVPMIEGYMF

UNC45A

771

Q9H3U1
IKMIQGKEDDIYLMV

WDR64

576

B1ANS9
SRVMDLKGQMIYIVE

GUCY1A1

361

Q02108
LTVVRKGGDMSKTMY

SLC8A3

416

P57103
KKMFRRGYIAMLAVD

NAA30

276

Q147X3
AGKVYDDMILAMSRV

MYOM2

1216

P54296
TKMIEGILYEMRVFA

MYBPC2

701

Q14324
GMIGEVVMKRAYMAV

GRIN2B

496

Q13224