Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

SHANK1 RIPK3 ARID3A SHB NUP98 NUP62 ZFPM1 MED13L MIDEAS RXRB YEATS2 GAS2L1 TARDBP KAT2B KMT2D MYOZ1 DGCR8 BRD1 SPEN CUX1

2.65e-06116010620GO:0030674
GeneOntologyMolecularFunctionmolecular adaptor activity

SHANK1 RIPK3 ARID3A SHB NUP98 NUP62 ZFPM1 MED13L MIDEAS RXRB YEATS2 GAS2L1 TARDBP KAT2B KMT2D MYOZ1 DGCR8 BRD1 SPEN CUX1

2.65e-05135610620GO:0060090
GeneOntologyMolecularFunctiontranscription coregulator activity

RIPK3 ARID3A NUP98 ZFPM1 MED13L MIDEAS RXRB YEATS2 KAT2B KMT2D SPEN

1.98e-0456210611GO:0003712
GeneOntologyMolecularFunctionstructural constituent of nuclear pore

NUP98 NUP62 NUP214

3.07e-04251063GO:0017056
GeneOntologyCellularComponentnuclear protein-containing complex

NUP50 SETD1B MYO1C CWC27 UBQLN4 NUP98 NUP62 NUP214 NABP1 MED13L MIDEAS RXRB PCF11 BOD1 ARNT KMT2D WDR6 PPIL2 DGCR8 TAF5 BRD1

4.80e-06137710621GO:0140513
DomainIF

KRT4 LZTS3 KRT19 KRT27 KRT28 KRT77

4.11e-06761046IPR001664
DomainKeratin_I

KRT4 KRT19 KRT27 KRT28 KRT77

4.44e-06441045IPR002957
DomainIF

KRT4 KRT19 KRT27 KRT28 KRT77

5.06e-05721045PS00226
DomainFilament

KRT4 KRT19 KRT27 KRT28 KRT77

5.40e-05731045PF00038
DomainSPOC_met

RBM15 SPEN

9.18e-0531042IPR010912
DomainSPOC

RBM15 SPEN

1.83e-0441042PS50917
Domain-

RBM15 SPEN

3.04e-04510422.40.290.10
DomainSPOC-like_C_dom

RBM15 SPEN

3.04e-0451042IPR016194
Domain-

RBM15 SETD1B LEMD3 TARDBP SPEN PSPC1 HNRNPLL

4.32e-0424410473.30.70.330
DomainSPOC_C

RBM15 SPEN

4.54e-0461042IPR012921
DomainSPOC

RBM15 SPEN

4.54e-0461042PF07744
DomainNucleotide-bd_a/b_plait

RBM15 SETD1B LEMD3 TARDBP SPEN PSPC1 HNRNPLL

6.02e-042581047IPR012677
DomainFilament

KRT19 KRT27 KRT28 KRT77

6.62e-04711044SM01391
PathwayREACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES

SETD1B YEATS2 BOD1 KAT2B KMT2D

3.30e-0642785M48018
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

NUP50 LEMD3 NUP98 NUP62 NUP214

1.06e-0553785M27212
PathwayREACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN

NUP50 NUP98 NUP62 NUP214

2.77e-0532784M29579
PathwayREACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS

NUP50 NUP98 NUP62 NUP214

3.14e-0533784M27016
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

NUP50 SETD1B MYO1C NUP98 NUP62 NUP214 ZFPM1 NABP1 RXRB PCF11 YEATS2 KAT2B ARNT KMT2D TAF5 BRD1 DYRK2

3.40e-0510227817MM15436
PathwayREACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN

NUP50 NUP98 NUP62 NUP214

3.55e-0534784M27041
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

NUP50 NUP98 NUP62 NUP214

3.99e-0535784M27320
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

NUP50 NUP98 NUP62 NUP214

4.47e-0536784M26974
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

NUP50 NUP98 NUP62 NUP214

4.47e-0536784M27245
PathwayREACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS

NUP50 NUP98 NUP62 NUP214

4.99e-0537784M1029
PathwayREACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS

NUP50 NUP98 NUP62 NUP214

4.99e-0537784M27038
PathwayREACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES

SETD1B YEATS2 KAT2B KMT2D

5.55e-0538784MM17073
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

NUP50 NUP98 NUP62 NUP214

6.16e-0539784M27238
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

NUP50 NUP98 NUP62 NUP214

6.81e-0540784MM14945
PathwayREACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS

NUP50 NUP98 NUP62 NUP214

7.52e-0541784M29574
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

NUP50 NUP98 NUP62 NUP214

7.52e-0541784MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

NUP50 NUP98 NUP62 NUP214

8.27e-0542784MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

NUP50 NUP98 NUP62 NUP214

9.09e-0543784MM14609
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

NUP50 NUP98 NUP62 NUP214

9.09e-0543784M26975
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

SETD1B ZFPM1 KAT2B KMT2D

9.95e-0544784MM15527
PathwayREACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS

NUP50 NUP98 NUP62 NUP214

9.95e-0544784M109
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT4 KRT19 KRT27 KRT28 KRT77

1.18e-0487785MM15351
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

NUP50 NUP98 NUP62 NUP214

1.19e-0446784M27397
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

NUP50 NUP98 NUP62 NUP214

1.29e-0447784M27395
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

NUP50 NUP98 NUP62 NUP214

1.29e-0447784MM14939
PathwayREACTOME_GENE_SILENCING_BY_RNA

NUP50 NUP98 NUP62 NUP214

1.52e-0449784MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

NUP50 NUP98 NUP62 NUP214

1.65e-0450784MM14610
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

NUP50 NUP98 NUP62 NUP214

1.78e-0451784MM15151
PathwayREACTOME_SNRNP_ASSEMBLY

NUP50 NUP98 NUP62 NUP214

2.22e-0454784M29594
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

NUP50 NUP98 NUP62 NUP214

2.39e-0455784MM14917
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

NUP50 NUP98 NUP62 NUP214

2.93e-0458784MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

NUP50 NUP98 NUP62 NUP214

2.93e-0458784MM14736
PathwayREACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS

NUP50 NUP98 NUP62 NUP214

3.13e-0459784M27606
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

NUP50 NUP98 NUP62 NUP214

4.55e-0465784MM15147
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

NUP50 NUP98 NUP62 NUP214

6.36e-0471784M27394
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

NUP50 NUP98 NUP62 NUP214

7.07e-0473784MM14948
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT4 KRT19 KRT27 KRT28 KRT77

7.35e-04129785M27649
PathwayREACTOME_ISG15_ANTIVIRAL_MECHANISM

NUP50 NUP98 NUP62 NUP214

7.44e-0474784M48006
PathwayWP_CELL_LINEAGE_MAP_FOR_NEURONAL_DIFFERENTIATION

SHANK1 CHAT TWIST1 ADRA2C CD34

8.15e-04132785M48110
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

NUP50 CWC27 NUP98 NUP62 NUP214 PCF11 PPIL2

8.43e-04277787MM15414
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

NUP50 NUP98 NUP62 NUP214

8.64e-0477784M27226
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

SETD1B MYO1C YEATS2 KAT2B KMT2D

9.32e-04136785MM14848
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

NUP50 CWC27 NUP98 NUP62 NUP214 PCF11 PPIL2

9.55e-04283787M13087
PathwayREACTOME_GENE_SILENCING_BY_RNA

NUP50 NUP98 NUP62 NUP214 DGCR8

1.03e-03139785M715
PathwayREACTOME_GLUCOSE_METABOLISM

NUP50 NUP98 NUP62 NUP214

1.09e-0382784MM15394
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

NUP50 NUP98 NUP62 NUP214

1.09e-0382784M27250
PathwayREACTOME_MITOTIC_PROPHASE

NUP50 LEMD3 NUP98 NUP62 NUP214

1.13e-03142785M27660
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

NUP50 NUP98 NUP62 NUP214

1.20e-0384784MM14929
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

NUP50 NUP98 NUP62 NUP214

1.20e-0384784M725
PathwayREACTOME_GLUCOSE_METABOLISM

NUP50 NUP98 NUP62 NUP214

1.25e-0385784M1870
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

NUP50 NUP98 NUP62 NUP214

1.31e-0386784MM15413
PathwayREACTOME_HIV_LIFE_CYCLE

NUP50 NUP98 NUP62 NUP214 TAF5

1.40e-03149785M4076
PathwayREACTOME_KERATINIZATION

KRT4 KRT19 KRT27 KRT28 KRT77

1.58e-03153785MM15343
PathwayREACTOME_RND3_GTPASE_CYCLE

LEMD3 CPD WDR6

1.60e-0342783M41826
PathwayREACTOME_RND1_GTPASE_CYCLE

LEMD3 CPD WDR6

1.60e-0342783M41828
PathwayBIOCARTA_NPC_PATHWAY

NUP62 NUP214

1.61e-0311782M22033
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

NUP50 NUP98 NUP62 NUP214

1.68e-0392784MM14951
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

SETD1B ZFPM1 KAT2B KMT2D

1.96e-0396784M27792
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

NUP50 NUP98 NUP62 NUP214

2.19e-0399784M27474
PathwayPID_HES_HEY_PATHWAY

TWIST1 ARNT SPEN

2.36e-0348783M288
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

NUP50 NUP98 NUP62 NUP214

2.36e-03101784M27253
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

SETD1B MYO1C YEATS2 BOD1 KAT2B KMT2D

2.81e-03254786M27131
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

NUP50 NUP98 NUP62 NUP214

2.81e-03106784M27458
PathwayWP_PRADERWILLI_AND_ANGELMAN_SYNDROME

NUP50 NUP98 NUP62 NUP214

3.11e-03109784M39542
Pubmed

Human transcription factor protein interaction networks.

ARID3A MYO1C NUP98 NUP62 NUP214 HRNR MIDEAS CIC PCF11 HOXA10 YEATS2 TARDBP KAT2B ARNT KMT2D UBN1 PURB PPIL2 TAF5 SPEN PCDH7 CUX1

4.46e-1014291082235140242
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 SETD1B ARID3A MTHFD1L NUP214 ZFPM1 MED13L CIC ADCY9 FZD7 GAS2L1 KMT2D UBN1 KCNH2 ZNRF1 LTBP3 SPEN CRAMP1 AHNAK2

1.35e-0911051081935748872
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

RBM15 MYO1C NUP98 NUP214 ZFPM1 CIC PCF11 YEATS2 OSBP KMT2D UBN1 PURB SPEN KLHDC4 PCDH7

1.83e-087741081515302935
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

NUP50 LEMD3 NUP98 NUP62 NUP214 MIDEAS CIC PCF11 YEATS2 ARNT KMT2D PSPC1

2.05e-084571081232344865
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

NUP50 RBM15 LEMD3 NUP98 NUP62 NUP214 MIDEAS CIC PCF11 YEATS2 TARDBP UBN1 DGCR8 SPEN PSPC1 CUX1

4.37e-089541081636373674
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

NUP50 RBM15 LEMD3 UBQLN4 NUP98 NUP62 NUP214 MIDEAS CIC HOXA10 YEATS2 TARDBP ARNT KMT2D UBN1 TAF5 SPEN CUX1

9.71e-0812941081830804502
Pubmed

Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence.

NUP98 NUP62 NUP214

1.16e-074108330543681
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

NUP50 NUP98 MUC19 NUP62 NUP214 YEATS2 AHNAK2

1.21e-07123108726912792
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

MYO1C KRT19 LEMD3 NUP98 GPRC5C HRNR ADCY9 PCF11 TARDBP DGCR8 SPEN HNRNPLL PCDH7 CUX1

1.38e-077771081435844135
Pubmed

Interaction network of human early embryonic transcription factors.

ARID3A NUP98 NUP214 HRNR MIDEAS KAT2B ARNT KMT2D WDR6 SPEN

1.56e-073511081038297188
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

ARID3A MIDEAS CIC KMT2D SPEN CUX1

2.42e-0783108628794006
Pubmed

Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1.

NUP98 NUP62 NUP214

2.90e-075108319828735
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NUP50 RBM15 ARID3A MED13L MIDEAS CIC PCF11 YEATS2 ARNT KMT2D PURB PPIL2 SPEN PSPC1 HNRNPLL CUX1

3.11e-0711031081634189442
Pubmed

Cofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin.

NUP98 NUP62 NUP214

1.01e-067108311238447
Pubmed

Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase.

NUP50 NUP98 NUP62 NUP214

1.06e-0625108410601273
Pubmed

Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.

NUP50 NUP98 NUP62 NUP214

1.25e-0626108412228227
Pubmed

New consensus nomenclature for mammalian keratins.

KRT4 KRT19 KRT27 KRT28 KRT77

1.60e-0663108516831889
Pubmed

Imaging within single NPCs reveals NXF1's role in mRNA export on the cytoplasmic side of the pore.

NUP98 NUP62 NUP214

1.61e-068108331375530
Pubmed

Cloning and characterization of human karyopherin beta3.

NUP98 NUP62 NUP214

2.41e-06910839114010
Pubmed

Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta.

NUP98 NUP62 NUP214

3.44e-0610108319581287
Pubmed

Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo.

NUP50 NUP98 NUP62 NUP214

3.80e-0634108418539113
Pubmed

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

NUP50 LEMD3 NUP98 NUP62 NUP214

4.35e-0677108524927568
Pubmed

A census of human transcription factors: function, expression and evolution.

FOXD2 SHOX2 GBX1 ZFPM1 MIDEAS CIC RXRB TWIST1 YEATS2 ARNT KMT2D EN2 CRAMP1

5.04e-069081081319274049
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SETD1B TRO NUP214 MED13L DNAJC6 YEATS2 CADPS MTCL1 SPEN

5.31e-06407108912693553
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

NUP50 NUP98 NUP62 NUP214

5.98e-0638108412791264
Pubmed

Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure.

NUP50 NUP98 NUP62 NUP214

7.37e-0640108437516964
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

RBM15 EMC7 MYO1C LEMD3 MTHFD1L SHB CPD GPRC5C ADCY9 WDR6 GLG1 PCDH7 CUX1

8.36e-069521081338569033
Pubmed

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.

SETD1B KRT19 MTHFD1L NUP98 NUP62 NUP214 MED13L ARNT HNRNPLL

8.41e-06431108933660365
Pubmed

OTX2 Transcription Factor Controls Regional Patterning within the Medial Ganglionic Eminence and Regional Identity of the Septum.

GBX1 CHAT SP8 EN2

8.99e-0642108426166575
Pubmed

Lentiviral Transfer of γ-Globin with Fusion Gene NUP98-HOXA10HD Expands Hematopoietic Stem Cells and Ameliorates Murine β-Thalassemia.

NUP98 HOXA10

9.55e-062108228190779
Pubmed

Nuclear distributions of NUP62 and NUP214 suggest architectural diversity and spatial patterning among nuclear pore complexes.

NUP62 NUP214

9.55e-062108222558357
Pubmed

HOXA10 suppresses p/CAF promoter activity via three consecutive TTAT units in human endometrial stromal cells.

HOXA10 KAT2B

9.55e-062108219084499
Pubmed

Delineating domains and functions of NUP98 contributing to the leukemogenic activity of NUP98-HOX fusions.

NUP98 HOXA10

9.55e-062108221130494
Pubmed

Angiogenesis-Centered Molecular Cross-Talk in Amyotrophic Lateral Sclerosis Survival: Mechanistic Insights.

UBQLN4 TARDBP

9.55e-062108232558493
Pubmed

Precocious chondrocyte differentiation disrupts skeletal growth in Kabuki syndrome mice.

SHOX2 KMT2D

9.55e-062108231557133
Pubmed

Splice site m6A methylation prevents binding of DGCR8 to suppress KRT4 pre-mRNA splicing in oral squamous cell carcinoma.

KRT4 DGCR8

9.55e-062108236811004
Pubmed

Brief report: ectopic expression of NUP98-HOXA10 augments erythroid differentiation of human embryonic stem cells.

NUP98 HOXA10

9.55e-062108221328509
Pubmed

High frequency of matrix attachment regions and cut-like protein x/CCAAT-displacement protein and B cell regulator of IgH transcription binding sites flanking Ig V region genes.

ARID3A CUX1

9.55e-062108212193717
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

CDV3 YEATS2 TARDBP UBN1 WDR6 MAP7D2 MTCL1 AHNAK2

9.75e-06332108837433992
Pubmed

TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.

NUP98 NUP62 NUP214

1.03e-0514108311073998
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

NUP50 CDV3 ARID3A YEATS2 TARDBP ARNT UBN1 PPIL2 AHNAK2

1.07e-05444108934795231
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

RBM15 CDV3 SETD1B MYO1C KRT19 NUP98 NUP62 TARDBP KMT2D GLG1 PSPC1

1.38e-057111081133022573
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

ARID3A TRO NUP98 HRNR CIC RXRB TWIST1 HOXA10 ARNT KMT2D SPEN CUX1

1.49e-058571081225609649
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

EMC7 LEMD3 CWC27 SHB NUP98 CPD NUP62 NUP214 BOD1 OSBP GLG1 MAP7D2 PSPC1

1.51e-0510071081334597346
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RBM15 KRT19 FAM117B NUP62 CIC MYLK2 KRT77 MTCL1 BRD1 PCDH7 AHNAK2 DYRK2

1.56e-058611081236931259
Pubmed

The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates.

NUP98 NUP62 NUP214

1.92e-0517108310668806
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ARID3A CWC27 MIDEAS CIC HOXA10 UBN1 PPIL2 BRD1 SPEN CUX1

2.07e-056081081036089195
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

NUP50 RELCH RBM15 MYO1C LEMD3 NUP98 CPD CIC ADCY9 PCF11 TARDBP KMT2D PCDH7

2.32e-0510491081327880917
Pubmed

Genome-wide atlas of gene expression in the adult mouse brain.

FOXD2 GBX1 RXRB CUX1

2.47e-0554108417151600
Pubmed

PCAF impairs endometrial receptivity and embryo implantation by down-regulating β3-integrin expression via HOXA10 acetylation.

HOXA10 KAT2B

2.86e-053108224037888
Pubmed

Regulation of the homeodomain CCAAT displacement/cut protein function by histone acetyltransferases p300/CREB-binding protein (CBP)-associated factor and CBP.

KAT2B CUX1

2.86e-053108210852958
Pubmed

Nup50 is required for cell differentiation and exhibits transcription-dependent dynamics.

NUP50 NUP98

2.86e-053108224943837
Pubmed

Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins.

CHAT TARDBP

2.86e-053108234824257
Pubmed

Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 Rev.

NUP98 NUP214

2.86e-05310829847314
Pubmed

Rbm15-Mkl1 interacts with the Setd1b histone H3-Lys4 methyltransferase via a SPOC domain that is required for cytokine-independent proliferation.

RBM15 SETD1B

2.86e-053108222927943
Pubmed

A role for nucleoporin FG repeat domains in export of human immunodeficiency virus type 1 Rev protein and RNA from the nucleus.

NUP98 NUP214

2.86e-05310828943370
Pubmed

Diagnostic use of cytokeratins, CD34, and neuronal cell adhesion molecule staining in focal nodular hyperplasia and hepatic adenoma.

KRT19 CD34

2.86e-053108219157505
Pubmed

Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A.

TWIST1 KAT2B

2.86e-053108210025406
Pubmed

Twist and p53 reciprocally regulate target genes via direct interaction.

TWIST1 KAT2B

2.86e-053108218504427
Pubmed

Upregulation of ATG7 attenuates motor neuron dysfunction associated with depletion of TARDBP/TDP-43.

CHAT TARDBP

2.86e-053108231242080
Pubmed

Disseminated tumor cells in bone marrow assessed by TWIST1, cytokeratin 19, and mammaglobin A mRNA predict clinical outcome in operable breast cancer patients.

KRT19 TWIST1

2.86e-053108220920982
Pubmed

Cut-like homeobox 1 and nuclear factor I/B mediate ENGRAILED2 autism spectrum disorder-associated haplotype function.

EN2 CUX1

2.86e-053108222180456
Pubmed

A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing.

RBM15 SPEN

2.86e-053108226190105
Pubmed

Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexes.

NUP98 NUP214

2.86e-053108212589057
Pubmed

The nuclear pore complex: a new dynamic in HIV-1 replication.

NUP98 NUP214

2.86e-053108221327100
Pubmed

Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathways.

NUP98 NUP62

2.86e-053108222334672
Pubmed

Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain.

FOXD2 MIDEAS RXRB CUX1

3.06e-0557108421122108
Pubmed

Ldb1 is essential for development of Nkx2.1 lineage derived GABAergic and cholinergic neurons in the telencephalon.

GBX1 CHAT CUX1

3.72e-0521108324157949
Pubmed

Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases.

MYO1C KRT19 MTHFD1L NUP98 NUP214 TARDBP AHNAK2

3.95e-05295108726209609
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYO1C KRT19 CWC27 TRO SHB NUP98 NUP62 MYLK2 PCF11 TARDBP KRT77 MAP7D2 SPEN PSPC1 CUX1

4.01e-0514421081535575683
Pubmed

Structural basis for activity regulation of MLL family methyltransferases.

SETD1B BOD1 KMT2D

4.30e-0522108326886794
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

RBM15 ARID3A NUP98 NUP62 ZFPM1 YEATS2 TARDBP PSPC1

4.47e-05411108835182466
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

CDV3 MIDEAS YEATS2 TARDBP KMT2D WDR6 TAF5 SPEN CUX1

5.59e-05549108938280479
Pubmed

Developmental Expression of Mutant PFN1 in Motor Neurons Impacts Neuronal Growth and Motor Performance of Young and Adult Mice.

CHAT TARDBP

5.71e-054108231611772
Pubmed

Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export.

RBM15 SPEN

5.71e-054108216129689
Pubmed

The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export.

NUP98 NUP214

5.71e-05410829368759
Pubmed

SET-NUP214 and MLL cooperatively regulate the promoter activity of the HoxA10 gene.

NUP214 HOXA10

5.71e-054108234320268
Pubmed

In vitro analysis of nuclear transport mediated by the C-terminal shuttle domain of Tap.

NUP98 NUP214

5.71e-054108211551912
Pubmed

The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia.

NUP98 HOXA10

5.71e-054108216861351
Pubmed

Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament.

KRT27 KRT28

5.71e-054108217920809
Pubmed

Aryl Sulfonamides Induce Degradation of Aryl Hydrocarbon Receptor Nuclear Translocator through CRL4DCAF15 E3 Ligase.

DCAF15 ARNT

5.71e-054108233168788
Pubmed

Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current.

KCNH2 EN2

5.71e-05410829351462
Pubmed

Assignment of mouse cardiac two-pore background K+ channel gene (Kcnk4) to the proximal region of mouse chromosome 5.

ADRA2C EN2

5.71e-05410829806851
Pubmed

Karyopherin-centric control of nuclear pores based on molecular occupancy and kinetic analysis of multivalent binding with FG nucleoporins.

NUP98 NUP62

5.71e-054108224739174
Pubmed

Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly.

NUP98 NUP62

5.71e-05410829348540
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

NUP50 CDV3 LZTS3 LEMD3 DUSP7 NUP62 CIC UBN1 PURB MTCL1

5.91e-056891081036543142
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

LEMD3 CWC27 MTHFD1L GPRC5C NUP62 CIC MYLK2 PCF11 GLG1 PURB DGCR8 TAF5 SPEN PSPC1 HNRNPLL

6.12e-0514971081531527615
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TRO NUP98 NUP214 HRNR CIC MAP3K1 UBN1 SPEN

6.13e-05430108835044719
Pubmed

The DNA sequence of human chromosome 7.

GBX1 TWIST1 HOXA10 KCNH2 PURB SRRM3 EN2 CUX1

7.31e-05441108812853948
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

NUP50 RBM15 NUP98 NUP62 NUP214 BRD1 PSPC1

8.29e-05332108725693804
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

SHOX2 CIC RXRB HOXA10 SP8 TARDBP KAT2B ARNT TAF5 BRD1 SPEN

9.20e-058771081120211142
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

RBM15 SETD1B KRT19 CIC YEATS2 ARNT UBN1 PPIL2 SPEN

9.42e-05588108938580884
Pubmed

Ott1 (Rbm15) is essential for placental vascular branching morphogenesis and embryonic development of the heart and spleen.

RBM15 CD34

9.50e-055108218981216
Pubmed

Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export.

NUP62 NUP214

9.50e-055108211425870
Pubmed

Nucleophosmin is essential for ribosomal protein L5 nuclear export.

NUP50 NUP62

9.50e-055108216648475
Pubmed

The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution.

RELCH OSBP

9.50e-055108229514919
Pubmed

The N-terminal domain of the mammalian nucleoporin p62 interacts with other nucleoporins of the FXFG family during interphase.

NUP62 NUP214

9.50e-055108216730000
Pubmed

Extensive brain hemorrhage and embryonic lethality in a mouse null mutant of CREB-binding protein.

TWIST1 CD34

9.50e-055108210906457
Pubmed

Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1.

NUP98 HOXA10

9.50e-055108214966272
Pubmed

Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy.

CHAT TARDBP

9.50e-055108235767949
InteractionHNF4A interactions

ARID3A MUC19 MIDEAS CIC YEATS2 KAT2B ARNT KMT2D UBN1 TAF5 SPEN CUX1

2.31e-0827510612int:HNF4A
InteractionNUP35 interactions

NUP50 LEMD3 NUP98 NUP62 NUP214 MIDEAS CIC PCF11 YEATS2 ARNT KMT2D PSPC1

2.38e-0642410612int:NUP35
InteractionSP7 interactions

ARID3A MIDEAS CIC PCF11 HOXA10 KAT2B ARNT KMT2D PCDH7 CUX1

4.67e-0630410610int:SP7
InteractionCXXC1 interactions

NUP50 SETD1B NUP98 YEATS2 BOD1 KMT2D DYRK2

6.27e-061321067int:CXXC1
InteractionTOP3B interactions

VWA5B2 RBM15 SETD1B ARID3A MYO1C MTHFD1L NUP214 ZFPM1 MED13L CIC ADCY9 FZD7 GAS2L1 KMT2D UBN1 KCNH2 ZNRF1 LTBP3 SPEN ADAMTSL4 CRAMP1 AHNAK2

6.65e-06147010622int:TOP3B
InteractionSOX9 interactions

ARID3A MIDEAS CIC KMT2D SPEN CUX1

1.23e-05971066int:SOX9
InteractionDYRK1A interactions

MYO1C LZTS3 NUP98 FAM117B NUP214 HRNR CIC MAP3K1 TARDBP KMT2D LTBP3 AHNAK2

3.36e-0555210612int:DYRK1A
InteractionTBXT interactions

ARID3A MIDEAS CIC KMT2D SPEN CUX1

3.41e-051161066int:TBXT
InteractionH3-3A interactions

SETD1B ARID3A CWC27 MIDEAS CIC MYLK2 HOXA10 KAT2B KMT2D UBN1 PPIL2 BRD1 SPEN CUX1

3.79e-0574910614int:H3-3A
InteractionTEAD1 interactions

ARID3A MIDEAS CIC HOXA10 ARNT KMT2D CUX1

4.05e-051761067int:TEAD1
InteractionSETD1B interactions

SETD1B YEATS2 BOD1 KMT2D DYRK2

4.72e-05751065int:SETD1B
InteractionWDR5 interactions

RBM15 CDV3 SETD1B MYO1C KRT19 NUP98 NUP62 CIC TWIST1 YEATS2 BOD1 TARDBP KAT2B KMT2D GLG1 PSPC1 DYRK2

5.93e-05110110617int:WDR5
InteractionHNF1B interactions

ARID3A MIDEAS CIC KAT2B KMT2D UBN1 CUX1

6.58e-051901067int:HNF1B
InteractionSMC5 interactions

NUP50 RBM15 LEMD3 NUP98 NUP62 NUP214 MIDEAS CIC PCF11 YEATS2 TARDBP UBN1 DGCR8 SPEN PSPC1 CUX1

6.60e-05100010616int:SMC5
InteractionMYB interactions

DCAF15 ARID3A CIC KAT2B KMT2D CUX1

7.33e-051331066int:MYB
InteractionNUP50 interactions

NUP50 CDV3 LEMD3 NUP98 NUP214 YEATS2 SPEN PSPC1 CUX1

7.96e-053411069int:NUP50
InteractionGATA2 interactions

ARID3A ZFPM1 MIDEAS CIC KMT2D ADAMTSL4 CUX1

8.79e-051991067int:GATA2
InteractionFEV interactions

ARID3A MIDEAS CIC ARNT KMT2D TAF5 CUX1

9.96e-052031067int:FEV
InteractionNUP43 interactions

NUP50 RBM15 SETD1B NUP98 MUC19 NUP62 NUP214 MIDEAS YEATS2 KMT2D SPEN AHNAK2

1.10e-0462510612int:NUP43
InteractionDYRK1B interactions

LZTS3 FAM117B CIC MAP3K1 WDR6

1.19e-04911065int:DYRK1B
InteractionPOLR2A interactions

SETD1B NABP1 MED13L CIC MYLK2 PCF11 KAT2B KMT2D UBN1 BRD1 PSPC1

1.21e-0453610611int:POLR2A
InteractionNUP58 interactions

KRT27 KRT28 NUP98 NUP62 NUP214

1.25e-04921065int:NUP58
InteractionRANBP1 interactions

NUP50 NUP98 NUP62 NUP214 HOXA10 TARDBP ARNT

1.27e-042111067int:RANBP1
InteractionTACC3 interactions

DCAF15 NUP62 KAT2B ARNT PCDH7 CUX1

1.32e-041481066int:TACC3
InteractionMAGEA10 interactions

YEATS2 KAT2B MTCL1 CUX1

1.38e-04501064int:MAGEA10
InteractionLAMP1 interactions

RELCH EMC7 RIPK3 LEMD3 SHB CPD ADCY9 FZD7 WDR6 PCDH7 CUX1 AHNAK2

1.45e-0464410612int:LAMP1
InteractionSOX17 interactions

ARID3A HRNR MIDEAS CIC KMT2D

1.46e-04951065int:SOX17
InteractionTERF2IP interactions

NUP50 ARID3A CWC27 CIC PCF11 YEATS2 ARNT PPIL2 DGCR8 SPEN CUX1

1.56e-0455210611int:TERF2IP
InteractionNFIX interactions

ARID3A MIDEAS CIC KMT2D TAF5 SPEN CUX1

1.99e-042271067int:NFIX
InteractionVAV3 interactions

RBM15 MAP3K1 TARDBP PSPC1

2.01e-04551064int:VAV3
InteractionC3orf52 interactions

LEMD3 ADCY9 YEATS2 OSBP LRP10 RELT CUX1 AHNAK2

2.10e-043051068int:C3orf52
InteractionH3C1 interactions

NUP50 SETD1B ARID3A LEMD3 MIDEAS MYLK2 KAT2B KMT2D UBN1 PPIL2 TAF5 BRD1 SPEN CUX1

2.65e-0490110614int:H3C1
Cytoband7p21.2

TWIST1 SP8

2.97e-041110827p21.2
Cytoband17q21.2

KRT19 KRT27 KRT28

6.18e-0470108317q21.2
Cytoband18p11.22

RAB12 MTCL1

7.29e-0417108218p11.22
GeneFamilyNucleoporins

NUP50 NUP98 NUP62 NUP214

1.05e-05327841051
GeneFamilyKeratins, type I

KRT19 KRT27 KRT28

2.34e-0428783608
GeneFamilyRNA binding motif containing

RBM15 SETD1B TARDBP SPEN PSPC1 HNRNPLL

3.16e-04213786725
GeneFamilyATAC complex

YEATS2 KAT2B

1.39e-03137821058
GeneFamilyCyclophilin peptidylprolyl isomerases

CWC27 PPIL2

3.00e-0319782909
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

JPH4 LZTS3 MUC19 SLCO3A1 SHOX2 C11orf87 FAM117B MED13L DNAJC6 CADPS ZNRF1 MAP7D2 BRD1 SRRM3 EN2 PCDH7 AHNAK2 PDE11A DYRK2

1.04e-07110610719M39071
CoexpressionGSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_DN

NUP50 SETD1B DUSP7 NUP62 NUP214 TAF5 BRD1

1.86e-052001077M5859
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBML5

JPH4 MUC19 SLCO3A1 FAM117B DNAJC6 CADPS MAP7D2 SRRM3 PCDH7 PDE11A

2.12e-0546510710M39066
CoexpressionKRAS.AMP.LUNG_UP.V1_DN

SHANK1 GPRC5C ADAMTS5 ADRA2C CD34 PDE11A

2.62e-051421076M2859
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

ARID3A DUSP7 MED13L ADCY9 PCF11 MTCL1 SPEN DYRK2

3.28e-053001078M8702
CoexpressionGSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN

DUSP7 DNAJC6 GAS2L1 OSBP KMT2D ZNRF1

4.61e-051571076M7733
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000

KRT4 RELCH SETD1B KRT19 C11orf87 CPD NUP214 ADAMTS5 TWIST1 FZD7 SP8 CADPS KANK4 MTCL1 PCDH7 CUX1

2.13e-0680610516gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
ToppCellNS-critical-d_07-13-Myeloid-Mast_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

JPH4 TRO HOXA10 CADPS KCNH2 MTCL1

3.34e-0616710868a14fd980d8ebe8ef0216221f619d31aaa27ff15
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LZTS3 SLCO3A1 ADAMTS5 TWIST1 CD34 TAF5

5.15e-061801086c4068fe47408cfd899131a85fa4b7e5908926f94
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXD2 TRO GBX1 ADAMTS5 TWIST1 GPR153

5.84e-0618410861c857126c0ea0671f0d60b048efca288d348d653
ToppCell3'_v3-Lung-Mast|Lung / Manually curated celltypes from each tissue

KRT19 CADPS KCNH2 ZNRF1 MTCL1 AHNAK2

7.90e-0619410865e6eb81ddc9d5e22c1297734689f476d5a05bff6
ToppCell3'_v3-Lung-Mast-Mast_cells|Lung / Manually curated celltypes from each tissue

KRT19 CADPS KCNH2 ZNRF1 MTCL1 AHNAK2

7.90e-0619410867b7f1714c4a9d9519c4d0e460cb87f2eb82392dd
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_granulocytic-basophil|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KRT19 CADPS KCNH2 ZNRF1 MTCL1 AHNAK2

7.90e-061941086aca009b9f1f320c0a65ea16df6595d7ede0b1fda
ToppCellfacs-Skin-nan-18m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAT MAP3K1 FZD7 CD34 LTBP3 ADAMTSL4

8.14e-061951086ba7cb80deb872c9184769f0dd57855c3c6a432bf
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO1C KRT19 DUSP7 FAM174B SLCO3A1 CUX1

8.62e-061971086b0fb5774525ba05f60c635d42f14bb8d79bff17c
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO1C KRT19 DUSP7 FAM174B SLCO3A1 CUX1

8.62e-061971086bbb7c106d5b96b8e95aeb3e5c293e104fceea234
ToppCellParenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LEMD3 MTHFD1L DUSP7 ADAMTS5 ARHGEF25 MYOZ1

9.40e-062001086a372ef3f9e6ff6e3c3376d6e10182977c5067788
ToppCellNS-moderate-d_07-13-Myeloid-Mast_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TRO HOXA10 CADPS KCNH2 MTCL1

3.93e-05156108517c38d3b03fc38cb125cf0d165b2fd694cd88edd
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JPH4 RIPK3 ZFPM1 RASIP1 CD34

3.93e-0515610851928c86deb3bcd01db4ae76919a351066aadb39a
ToppCellNS-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TRO FZD7 CADPS KCNH2 MTCL1

4.43e-0516010858a4746463ca1976f7d6de803496c851249ced797
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 KRT19 HOXA10 CADPS SRRM3

5.13e-0516510854b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCellcritical-Myeloid-Mast_cell|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

JPH4 TRO CADPS KCNH2 MTCL1

5.13e-05165108534a1cc6ccd46c059354e8fbde1ac69f202695a4e
ToppCellmoderate-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TRO HOXA10 CADPS KCNH2 MTCL1

5.28e-051661085c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCellfacs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 FZD7 GPR153 CD34 LTBP3

5.43e-05167108578909f685ccd1321064eb0887caf9263e0e54879
ToppCellBL-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

JPH4 MUC19 FZD7 KCNH2 PDE11A

5.91e-051701085b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-Progenitor_(NEUROG3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 KRT19 SLCO3A1 HRNR CADPS

6.08e-051711085c54dcad75fc378da1943009d7dd872b39ea337c0
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRO ADAMTS5 TWIST1 GPR153 KANK4

6.25e-051721085073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT28 NABP1 ADRA2C BAIAP2L2 PDE11A

6.42e-0517310850a355386210a13927ea29b10b64cb059459952d4
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT28 NABP1 ADRA2C BAIAP2L2 PDE11A

6.42e-0517310853678b300cad4effd7f49bfb043305ed512693848
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXD2 C11orf87 ADCY9 KANK4 MAP7D2

6.60e-051741085197686570cec6d96a92e77e6409325d3bfe6f991
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXD2 C11orf87 ADCY9 KANK4 MAP7D2

6.60e-0517410852eee7b5471672b439f95eba11494c2adf8cb7006
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GBX1 ADAMTS5 DNAJC6 PCDH7 AHNAK2

6.60e-051741085a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellmoderate-Myeloid-Mast_cell|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TRO HOXA10 CADPS KCNH2 MTCL1

6.78e-051751085bbd2971bc6d69e507f90a637834d0936c205c590
ToppCellAT1_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

KRT4 MYO1C KRT19 FAM174B AHNAK2

7.15e-0517710853128b8d04687acee1ac4190b2569d6328b98eaf3
ToppCellcontrol-Others-CD34+_GATA2+_cells|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

DNAJC6 HOXA10 KCNH2 CD34 ZNRF1

7.35e-0517810852120bd3e099b0b271bf079db9827a2f3eee2f909
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JPH4 GOLM1 ADAMTS5 MYLK2 AHNAK2

7.35e-051781085a107dd98a07086ed0429116095ecda60c9dbef1e
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRO HOXA10 KCNH2 CD34 ZNRF1

7.54e-0517910854bb2debfc9e9f258cd38e797ef160bd440aad6af
ToppCellPBMC-Mild-Hematopoietic-HSPC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRO HOXA10 KCNH2 CD34 ZNRF1

7.54e-0517910852f690f933bf6b99abeb31766e0b22bdbe36c1ba0
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRO HOXA10 KCNH2 CD34 ZNRF1

7.54e-0517910853e2c937369b8190fd5d5a31689d029e6e89fb5e2
ToppCellfacs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C11orf87 GPRC5C ARHGEF25 KANK4 MAP7D2

7.74e-0518010850059e5acade6c895fd629767bea1c15f40b0d1b0
ToppCellfacs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C11orf87 GPRC5C ARHGEF25 KANK4 MAP7D2

7.74e-051801085dfb8412e1e06fa7349e66eea2ef27d9ea98b7893
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TRO HOXA10 KCNH2 CD34 ZNRF1

7.95e-051811085e7f7b519c2a01c15f26df11ec9b434c0d1630c7a
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT4 GPRC5C ADAMTS5 KAT2B RELT

7.95e-05181108541969fe4d94ee77b12ecde32170aaf0b13e49644
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT4 GPRC5C ADAMTS5 KAT2B RELT

7.95e-0518110853f50e61dc2a52d71a5801584617607e6246adcf2
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TRO HOXA10 KCNH2 CD34 ZNRF1

7.95e-05181108554a19cf6a3b752e2391feb8b316bebee0e602d17
ToppCellPBMC-Mild-Hematopoietic-HSPC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TRO HOXA10 KCNH2 CD34 ZNRF1

7.95e-0518110855b84625b1d3737708001b64f6da9360330d39a27
ToppCellcritical-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

JPH4 TRO CADPS KCNH2 MTCL1

7.95e-051811085f0d81ae74d3f32979624a94b2ef93774831a7970
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRO ADAMTS5 RASIP1 CD34 KANK4

8.16e-051821085f4a5f1c3a04c0566eb96607dab7a0d9a5ebc3fd1
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXD2 JPH4 ADAMTS5 ARHGEF25 KANK4

8.37e-051831085f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 JPH4 GPRC5C KCNC4 CADPS

8.59e-0518410853da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCellfacs-Skin-nan-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO3A1 GBX1 GAS2L1 KCNH2 KRT77

8.59e-051841085dc7f6ee4062856a02423fff8b1cce62d46a9355c
ToppCellfacs-BAT-Fat-24m-Epithelial-Epcam+|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTHFD1L CHAT GOLM1 FZD7 BAIAP2L2

9.04e-051861085b18d7398279a2d42414318aeb70514fd402f5a0a
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS5 TWIST1 KCNC4 MAP7D2 PCDH7

9.27e-051871085218c9b4f28499389c43005d9626af2ac01066027
ToppCell10x5'-Lung-Mast|Lung / Manually curated celltypes from each tissue

KRT19 CADPS KCNH2 MTCL1 AHNAK2

9.27e-051871085f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCell10x5'-Lung-Mast-Mast_cells|Lung / Manually curated celltypes from each tissue

KRT19 CADPS KCNH2 MTCL1 AHNAK2

9.27e-051871085da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS5 TWIST1 KCNC4 MAP7D2 PCDH7

9.27e-051871085c7ac4b328efc2ebb72f71154661914193ff402ca
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SHOX2 ADAMTS5 TWIST1 MAP7D2 LTBP3

9.50e-051881085bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCellE17.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYO1C KRT19 FAM174B SLCO3A1 CUX1

9.99e-05190108515f314517ed47b12d287a12a7d18cb383310e25a
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_granulocytic-mast_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KRT19 CADPS KCNH2 ZNRF1 AHNAK2

9.99e-0519010857774dc0b4ae7d5920b516800f3b90cbf831f8d3d
ToppCell15-Trachea-Epithelial-Neuroendocrine|Trachea / Age, Tissue, Lineage and Cell class

VWA5B2 JPH4 CADPS KCNH2 SRRM3

1.02e-04191108576311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCellfacs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO3A1 DNAJC6 WDR6 CD34 LTBP3

1.05e-04192108503dcd9405d3d76fc7455066ba5d83c09cd17072d
ToppCelldistal-Hematologic-Basophil/Mast_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RELCH CADPS KCNH2 MTCL1 AHNAK2

1.07e-041931085f22d0a2ea6bbdd625909ccb6a89aca89ab670306
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KRT19 MYLK2 RASIP1 KCNC4 CD34

1.07e-0419310853f8280ef849d95b2fcea5e6824b95a07febc96d0
ToppCellfacs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K1 FZD7 CD34 LTBP3 ADAMTSL4

1.07e-041931085eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCelldistal-Hematologic-Basophil/Mast_2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RELCH CADPS KCNH2 MTCL1 AHNAK2

1.07e-041931085dcdc1498726c68bf590bf84cb81e5f7fb7ba4d78
ToppCelldistal-3-Hematologic-Basophil/Mast_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RELCH CADPS KCNH2 MTCL1 AHNAK2

1.07e-04193108523c6c798525dad43eff792727902ea562bf373be
ToppCellfacs-Thymus-nan-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NABP1 MAP3K1 WDR6 ZNRF1 CUX1

1.10e-041941085f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCellfacs-Marrow-KLS-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPK3 SLCO3A1 NUP62 DNAJC6 CD34

1.10e-041941085c9ebdcc2ea600975dade68a41fa65d1f8a5a5926
ToppCellfacs-Thymus-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NABP1 MAP3K1 WDR6 ZNRF1 CUX1

1.10e-041941085cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO1C KRT19 FAM174B SLCO3A1 CUX1

1.10e-041941085a281ebab117589fc922ead0a712cfe0a844c94ac
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO1C KRT19 FAM174B SLCO3A1 CUX1

1.10e-041941085ad3eb98f94a007c5988ede06238255f5b03bee6e
ToppCellfacs-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NABP1 MAP3K1 WDR6 ZNRF1 CUX1

1.10e-04194108566c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCellfacs-Skin-Anagen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K1 FZD7 CD34 LTBP3 ADAMTSL4

1.10e-0419410855d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCelldistal-Hematologic-Nonclassical_Monocyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FAM117B NUP214 MAP3K1 RELT CUX1

1.13e-0419510856f417bb464b8ae6a50bbab5db5a6d5760c02122f
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

JPH4 CHAT CADPS KCNH2 SRRM3

1.16e-0419610854bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCellfrontal_cortex-Neuronal|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SHANK1 TRO DNAJC6 CADPS MAP7D2

1.16e-041961085de7d10da862f98894ce47244fbc992f4a12d63bb
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT4 KRT19 GOLM1 CPD AHNAK2

1.18e-0419710855c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCellfacs-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS5 GLG1 GPR153 CD34 LTBP3

1.21e-0419810850dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCellControl_saline-Epithelial_alveolar-AT_1-AT1|Control_saline / Treatment groups by lineage, cell group, cell type

KRT19 GOLM1 GPRC5C MYOZ1 LTBP3

1.21e-0419810859f972f217d2c39d4c0f7d0d4227d0fffe8535b9d
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DNAJC6 GAS2L1 KCNH2 CD34 ZNRF1

1.21e-0419810858be58e41ae7870d268e7ce5ab937769e2ecb60d9
ToppCellCOVID-19-COVID-19_Mild-Others-HSPC|COVID-19_Mild / Disease, condition lineage and cell class

DNAJC6 HOXA10 KCNH2 CD34 ZNRF1

1.24e-0419910850230103c37ae3aff58240739b89f2c36b1e39a69
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ADAMTS5 ARHGEF25 KCNH2 LTBP3 SRRM3

1.24e-0419910856b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

JPH4 SLCO3A1 CADPS GPR153 CUX1

1.27e-042001085bad32a95b759fad509401b07bc96a56687c2a592
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TRO DUSP7 ADRA2C MYOZ1 CRAMP1

1.27e-042001085410b1a31de21c57d87ca2104f61cf4a7d4dd2f30
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

ADAMTS5 ARHGEF25 KCNH2 LTBP3 MTCL1

1.27e-042001085593bf6a7c557437db9a9249a5058a46014179ef6
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ADAMTS5 ARHGEF25 KCNH2 LTBP3 MTCL1

1.27e-042001085dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCelldroplet-Skin-nan-21m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAT ARHGEF25 FZD7 CD34 ADAMTSL4

1.27e-04200108569295705fc614c2687f2b6c8e6aa0c6717841008
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Grm1-Inhibitory_Neuron.Gad1Gad2_Sst.Grm1_(Interneuron,_OLM3_(CA1_enriched?))-|Hippocampus / BrainAtlas - Mouse McCarroll V32

KRT19 GBX1 HOXA10

3.22e-0455108310e98fc862d89141512bdebae1231ef1a82105b0
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Grm1-Inhibitory_Neuron.Gad1Gad2_Sst.Grm1_(Interneuron,_OLM3_(CA1_enriched?))|Hippocampus / BrainAtlas - Mouse McCarroll V32

KRT19 GBX1 HOXA10

3.22e-04551083a55d3edca2dd9ca7a703b2b3a5941b30b5f0a6df
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Grm1|Hippocampus / BrainAtlas - Mouse McCarroll V32

KRT19 GBX1 HOXA10

3.22e-04551083bac333ea3914a49376105dd977a0b8493b0d2001
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_stem_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SHANK1 CDV3 C11orf87 SP8

3.45e-041371084ed81624b9167255ce88dcf6ad7f1636376ea0525
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_stem_cell-Mesenchymal_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SHANK1 CDV3 C11orf87 SP8

3.45e-04137108447859aa25f32367461c1ec75ed9060bee430c6b7
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_B1-4|TCGA-Thymus / Sample_Type by Project: Shred V9

NUP50 CDV3 NUP214 TAF5

3.75e-04140108421e5f55a98b819d3638ec971d5029b2fcbd1ebc7
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LZTS3 MAP7D2 SRRM3 PDE11A

3.95e-041421084819e983688d126d89a71abc03d72525cc759a347
ToppCellTCGA-Uterus|World / Sample_Type by Project: Shred V9

TRO MYLK2 TWIST1 KANK4

4.17e-0414410847efb45286ebf2dbfb9125fd6373f28dccb029a2e
ToppCellChildren_(3_yrs)-Immune-mast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRO CADPS KCNH2 AHNAK2

4.98e-041511084bbf735c6433c3fc2feedb24ed6f48c51d545fb60
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 KRT27 CPD HOXA10

5.50e-0415510848fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

JPH4 MTHFD1L HOXA10 RASIP1

5.77e-041571084f896997490bb2eec598c6581f161220e70f9a991
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

JPH4 MTHFD1L HOXA10 RASIP1

5.77e-04157108414a8516346a89a89f1119b744625bd9844a74a03
ToppCellCOVID_non-vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TRO KCNH2 CD34 MAP7D2

5.91e-0415810840d4fe87fc7901dd5f9c004e91708a03cafdb4ad9
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JPH4 ADAMTS5 MAP7D2 AHNAK2

6.19e-0416010848624f101828efd32cdd38a65df8d94d690720a63
ToppCellNS-critical-d_16-33-Myeloid-Mast_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TRO CADPS KCNH2 MTCL1

6.19e-041601084c61869d9dbba250270e59366e15af204e5b4395d
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JPH4 ADAMTS5 MAP7D2 AHNAK2

6.19e-0416010849de3dd6b9d4b51314d60b3b01f4132bcfa2dfc18
ToppCelllymphoid-T_cell-pro-T_cell|T_cell / Lineage, cell class and subclass

RAB12 MYO1C SHOX2 MIDEAS

6.19e-04160108466fe86d2f37983761141e5bb3de127f0b4bb0951
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Lamp5-Cplx3_(Substantia_Innominata_(SI))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SP8 BAIAP2L2 PDE11A

6.28e-046910833074ec10315fb21048215125ec08b0d7922da3d9
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Lamp5-Cplx3_(Substantia_Innominata_(SI))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SP8 BAIAP2L2 PDE11A

6.28e-04691083f731d4500b139a8bef5c9185368509bf5a3791db
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Lamp5-Cplx3_(Substantia_Innominata_(SI))--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SP8 BAIAP2L2 PDE11A

6.28e-0469108340eb84fe36da5a4a82bd9b2d962b829e2c97a059
Drug17-DMAG; Down 200; 0.1uM; MCF7; HT_HG-U133A

ADCY9 PCF11 YEATS2 ARNT KCNH2 PPIL2 DGCR8 MTCL1

3.17e-0619110685210_DN
DrugNadide [53-84-9]; Up 200; 6uM; HL60; HT_HG-U133A

DCAF15 TRO SHB SLCO3A1 NABP1 MAP3K1 GAS2L1 PPIL2

3.69e-0619510682529_UP
DrugICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A

DCAF15 CDV3 NUP214 ADCY9 FZD7 ARNT DGCR8

2.77e-0518710676872_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA

DUSP7 SHB GPRC5C ADCY9 PCF11 GAS2L1 DGCR8

3.17e-051911067998_DN
DrugPimozide [2062-78-4]; Up 200; 8.6uM; HL60; HG-U133A

MYO1C MED13L TWIST1 GPR153 KLHDC4 PCDH7 CUX1

3.28e-0519210671562_UP
Drugcycloxydim

DUSP7 NUP62 FZD7 CD34

3.56e-05401064CID000091765
DrugAcacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A

LZTS3 FAM174B CPD ADCY9 ARNT KCNH2 PPIL2

3.62e-0519510673942_DN
DrugSR-95639A [115767-94-7]; Down 200; 10uM; HL60; HT_HG-U133A

DCAF15 MYO1C CIC GLG1 PPIL2 KLHDC4 DYRK2

3.62e-0519510671336_DN
DrugNiacin [59-67-6]; Up 200; 32.4uM; MCF7; HT_HG-U133A

LZTS3 SHOX2 GPRC5C CIC ADCY9 FZD7 PPIL2

3.74e-0519610675301_UP
DrugDydrogesterone [152-62-5]; Down 200; 12.8uM; MCF7; HT_HG-U133A

ARID3A LZTS3 SHB PCF11 WDR6 KCNH2 PPIL2

3.74e-0519610672811_DN
DrugNetilmicin sulfate [56931-57-2]; Down 200; 2.8uM; HL60; HT_HG-U133A

MYO1C SHOX2 CIC HOXA10 ARNT GLG1 PPIL2

3.74e-0519610672963_DN
DrugMimosine [500-44-7]; Up 200; 20.2uM; PC3; HT_HG-U133A

NUP98 CHAT MAP3K1 KMT2D PPIL2 DGCR8 DYRK2

3.86e-0519710676703_UP
DrugIvermectin [70288-86-7]; Down 200; 4.6uM; MCF7; HT_HG-U133A

CPD ADCY9 TARDBP ADRA2C GLG1 PPIL2 DYRK2

3.86e-0519710677206_DN
DrugDoxepin hydrochloride [1229-29-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A

DCAF15 ARID3A FAM174B ADCY9 YEATS2 OSBP DGCR8

3.99e-0519810677415_DN
DrugAminocaproic acid [60-32-2]; Down 200; 30.4uM; MCF7; HT_HG-U133A

LZTS3 SHB CPD ARNT KCNH2 GPR153 DYRK2

3.99e-0519810676501_DN
DrugNeostigmine bromide [114-80-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A

SETD1B DUSP7 FAM174B SLCO3A1 CIC ADRA2C PPIL2

3.99e-0519810675335_DN
Drug1,1-dimethylbiguanide hydrochloride; Down 200; 10uM; MCF7; HG-U133A

DCAF15 LZTS3 SLCO3A1 CPD YEATS2 PPIL2 DYRK2

4.12e-05199106761_DN
DrugNorcyclobenzaprine [303-50-4]; Up 200; 15.4uM; HL60; HT_HG-U133A

FOXD2 LZTS3 SHOX2 HOXA10 GAS2L1 MYOZ1 PPIL2

4.12e-0519910672469_UP
DrugDoxylamine succinate [562-10-7]; Up 200; 10.2uM; MCF7; HT_HG-U133A

SHANK1 LZTS3 SHOX2 CPD MAP3K1 FZD7 RASIP1

4.12e-0519910674819_UP
DrugPimethixene maleate [13187-06-9]; Up 200; 9.8uM; HL60; HT_HG-U133A

FOXD2 LZTS3 SHB RASIP1 GAS2L1 ARNT MYOZ1

4.25e-0520010672395_UP
Drugdeoxycortisone

CPD TWIST1

6.42e-0531062CID000102178
DiseaseNonorganic psychosis

SHANK1 SP8 KCNH2 CD34 DGCR8

5.09e-06691065C0349204
DiseasePsychotic Disorders

SHANK1 SP8 KCNH2 CD34 DGCR8

3.28e-051011065C0033975
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

MAP3K1 KMT2D SPEN

5.73e-04451063DOID:3748 (is_implicated_in)
Diseasefrontotemporal dementia (implicated_via_orthology)

UBQLN4 TARDBP

8.24e-04121062DOID:9255 (implicated_via_orthology)
Diseasecup-to-disc ratio measurement

FOXD2 MTHFD1L KAT2B GLG1 LTBP3 MTCL1 CUX1

9.39e-044301067EFO_0006939
Diseasepallidum volume change measurement

CWC27 ADCY9

9.72e-04131062EFO_0021494
Diseasereceptive language perception, parental genotype effect measurement

MUC19 PCDH7

1.13e-03141062EFO_0005686, EFO_0005939
Diseasepartial epilepsy

ADCY9 FZD7

1.68e-03171062EFO_0004263
DiseaseJT interval

ZFPM1 ARNT KCNH2 LTBP3 CUX1

2.05e-032481065EFO_0007885
DiseaseMyopia

MED13L ADRA2C UBN1 GLG1 PCDH7 PDE11A

2.71e-033851066HP_0000545
Diseaseanthropometric measurement

SHOX2 ADAMTS5 HOXA10 LTBP3

3.21e-031681064EFO_0004302
DiseaseLeukemia, Myelocytic, Acute

NUP98 NUP214 GAS2L1 CUX1

3.56e-031731064C0023467

Protein segments in the cluster

PeptideGeneStartEntry
IASGNSGPGIQGGGA

ARNT

21

P27540
GFGGARSEQEPGGGL

BRD1

826

O95696
SEALGGGVRGGTQPG

ARHGEF25

391

Q86VW2
LGPGQGEAGAGTGQS

ADAMTSL4

876

Q6UY14
FIVQGGDPTGTGSGG

CWC27

61

Q6UX04
GDPTGTGSGGESIYG

CWC27

66

Q6UX04
GSVGIAGFVPAGGGT

ADAMTS5

106

Q9UNA0
EKGSGGSGGGSQPRA

CUX1

851

P39880
AGPNASGAGERGSGG

ADRA2C

16

P18825
PGNTTRFGSGAAGGS

FAM174B

51

Q3ZCQ3
ACPFGGSVGDGVGIG

DGCR8

161

Q8WYQ5
SQGPTFGVKGGAAGG

MTHFD1L

456

Q6UB35
GAGAGTRPGDGGTAS

CDV3

51

Q9UKY7
VPSGGGRFSGFGSGA

NUP50

66

Q9UKX7
GLGAGSPALSGGQGR

RAB12

16

Q6IQ22
VFGRGGNSSGRGGSP

RASIP1

406

Q5U651
GGGGQRSLSPGGAAL

RBM15

286

Q96T37
QGGDPTGTGTGGESY

PPIL2

331

Q13356
GDGGGGGRSFSQPEA

HNRNPLL

51

Q8WVV9
GGRSIPSGVSGGFAG

MTCL1

281

Q9Y4B5
SAGGRLETSVQGGGG

LEMD3

301

Q9Y2U8
GNPGSVTIFGGSVGG

CES1P1

211

Q9UKY3
AGVGGAGGREPSTAS

RELCH

156

Q9P260
SGGGAGGLQPSSRAG

CADPS

71

Q9ULU8
FGTPFGGGTGGFGTT

NUP98

6

P52948
TSTTGFGTNPGGLFG

NUP98

261

P52948
SGAGSVRPLNGGAGF

KRT28

16

Q7Z3Y7
GGLGGGSVRFGPGVA

KRT19

16

P08727
TGPAREGGAVGGQDG

LRP10

596

Q7Z4F1
GFSGSVGGQNPSTGG

MED13L

1606

Q71F56
GTRTGGGGSQGSFPG

LZTS3

56

O60299
GGSGTGSRPEGTARG

MAP7D2

6

Q96T17
AGTAEGPGGGGSARI

KAT2B

61

Q92831
RSGGAGGAGAPGAVV

KCNH2

181

Q12809
GPRGFSCGSAIVGGG

KRT4

11

P19013
GDEGGSPASGSRGGF

JPH4

181

Q96JJ6
SRSNSFGERPGGGGG

BAIAP2L2

311

Q6UXY1
GSGTTALPGGFRTGN

MUC19

8036

Q7Z5P9
LDASEGGGGTNPGGR

PCDH7

226

O60245
GGGGTNPGGRSSVFE

PCDH7

231

O60245
TSSQGPKGEGDRGGG

MYLK2

71

Q9H1R3
CRGGSSVGGGTGPNG

PDE11A

66

Q9HCR9
DGAGGRGSEGSQSPG

ZFPM1

656

Q8IX07
EPGGLRAAGGGGSTS

GPR153

571

Q6NV75
GSGQSPGHGQRGSGS

HRNR

886

Q86YZ3
GSGQSPGHGQRGSGS

HRNR

1121

Q86YZ3
GSGQSPGHGQRGSGS

HRNR

1591

Q86YZ3
GSGQSPGHGQRGSGS

HRNR

2061

Q86YZ3
GSGQSPGHGQRGSGS

HRNR

2531

Q86YZ3
GAGNTCGVPGIGSGF

KRT27

31

Q7Z3Y8
FGQSPGFGQGGSVFG

NUP214

1806

P35658
GSVFGSGNTGRGGGF

NUP214

1871

P35658
RGGGFFSGLGGKPSQ

NUP214

1881

P35658
GKRNEAASPGSGGGG

HOXA10

86

P31260
FGGTGAPTGGFTFGT

NUP62

6

P37198
RGDAGPGSGAASGTV

OSBP

36

P22059
RGSGEGGPQGNSSAG

GPRC5C

181

Q9NQ84
GPIGQAGGGGFRFEG

PCF11

836

O94913
VGQNTSDGSGGPGGG

FZD7

161

O75084
FVSFVGQAGGGGPAG

GLG1

46

Q92896
GGGGGPGTAFSIDSL

GBX1

16

Q14549
PGGGDGFLTGLATGT

GAS2L1

46

Q99501
HGSPTRSGGGGGGNN

FAM117B

51

Q6P1L5
ATGATGASGGGGPIN

BOD1

26

Q96IK1
AVGSGNAGGSGPRGK

CRAMP1

101

Q96RY5
DLFGGGGAAGPTQAG

DNAJC6

526

O75061
GFGDGGPSGASGRDN

CPD

196

O75976
RAGSEPGAGSGSGAG

DUSP7

26

Q16829
SSGDSGGVPRRVGGG

ADCY9

56

O60503
TGRFCQVPAGGAGGG

LTBP3

136

Q9NS15
RGPERGGGGGVSDSS

MIDEAS

106

Q6PJG2
TEQEGGPQGGTRGAG

KANK4

506

Q5T7N3
EGGSRPACGGAGTQG

KLHDC4

366

Q8TBB5
VPGAAAEGSGGSGVG

EMC7

26

Q9NPA0
GGGGSSPGEADTGRR

EN2

31

P19622
GGRGFGGAGELGQTP

GOLM1

286

Q8NBJ4
PGLGAGATRSGVGTG

DYRK2

31

Q92630
TENGGGQGYSSGPGT

CD34

331

P28906
KSERNSGAGSGGGGP

DCAF15

6

Q66K64
SGSERGGGGGPCGFQ

PURB

6

Q96QR8
GGGAGAGQRPSFSID

FOXD2

401

O60548
GARATSPEAGGGGGA

MAP3K1

16

Q13233
PQAGDGAGEGSGGTT

TAF5

26

Q15542
GSGQRSGAHGGRPGS

SRRM3

316

A6NNA2
GTGTFGPVGNGVHTG

NABP1

141

Q96AH0
GGSGEPGGVQRAFSA

SHB

116

Q15464
PGGSSGGGRSGELQG

SLCO3A1

6

Q9UIG8
ERSGRFGGNPGGFGN

TARDBP

271

Q13148
RSSPAVRAAGGGGGG

SHOX2

51

O60902
DLPFGAVGGTGGSSG

SETD1B

351

Q9UPS6
SVFQAPGVSGGSGGG

SP8

126

Q8IXZ3
DQGVEGPGGTGGSGS

RXRB

316

P28702
GLFDIRGSPTGGAGG

SHANK1

2031

Q9Y566
GSGQGPSSTGQPGRG

AHNAK2

331

Q8IVF2
GNTGTSGGQAGPAGL

ARID3A

566

Q99856
IAQGAPGGGTTAGSG

CIC

781

Q96RK0
FLQSGGRGDPGDVGG

CHAT

36

P28329
GNTGARGPGAVGSGT

C11orf87

31

Q6NUJ2
SREVSGFRGGGGGPA

SPEN

101

Q96T58
FQGGSQSGTGSGEPG

RIPK3

166

Q9Y572
QSGTGSGEPGGTLGY

RIPK3

171

Q9Y572
GFSGGPSTGVGFCSG

TRO

1366

Q12816
GPGGFGRGSQGGNFE

PSPC1

501

Q8WXF1
GGSETGVGEGGPAQG

SLC26A1

576

Q9H2B4
RGRSAAAAGPGQGGG

TMEM275

91

A0A0U1RQS6
GSSGGGNAFTGLGPV

WDR6

546

Q9NNW5
GGETRQPGNGTRAGG

RELT

141

Q969Z4
SSGSEGPGQVDSGRG

VWA5B2

1131

Q8N398
GGPNGDSSGGTQGVA

UBN1

971

Q9NPG3
GGEGTGGSGTSQVHP

UBQLN4

346

Q9NRR5
SSRRSAGGGAGPGGA

TWIST1

41

Q15672
SRGTGDSERAPGGGG

ZNRF1

76

Q8ND25
GGGTQSTAGPGGISQ

YEATS2

831

Q9ULM3
GGRPETDGGGVGSSG

KCNC4

71

Q03721
GRSTSGFCQGGGVGG

KRT77

76

Q7Z794
SGGAGSLAGPSGGFF

KMT2D

3686

O14686
GSITFAGGPGRDGTI

MYO1C

1021

O00159
GPAGQAGRGGAAGTA

MYOZ1

146

Q9NP98