Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	FBN1 EFEMP1 HMCN2 LAMA3 LTBP1 COLQ SSPOP	1.33e-05	188	83	7	GO:0005201
GeneOntologyMolecularFunction	hyaluronan synthase activity	HAS2 HAS3	1.02e-04	4	83	2	GO:0050501
GeneOntologyMolecularFunction	calcium ion binding	PLSCR4 SELE SELP FBN1 EFEMP1 HMCN2 EGF LRP2 LTBP1 SVEP1 RYR1	2.65e-04	749	83	11	GO:0005509
GeneOntologyCellularComponent	basement membrane	FBN1 EFEMP1 HMCN2 LAMA3 COLQ USH2A	9.13e-06	122	83	6	GO:0005604
Domain	EGF_1	SELE SELP FBN1 EFEMP1 TENM4 HMCN2 EGF LRP2 LAMA3 LRP6 LTBP1 USH2A SSPOP SVEP1 TMEFF2	3.12e-13	255	82	15	PS00022
Domain	EGF_2	SELE SELP FBN1 EFEMP1 TENM4 HMCN2 EGF LRP2 LAMA3 LRP6 LTBP1 SSPOP SVEP1 TMEFF2	8.85e-12	265	82	14	PS01186
Domain	EGF_3	SELE SELP FBN1 EFEMP1 TENM4 HMCN2 EGF LRP2 LRP6 LTBP1 SSPOP SVEP1 TMEFF2	2.94e-11	235	82	13	PS50026
Domain	EGF-like_dom	SELE SELP FBN1 EFEMP1 TENM4 HMCN2 EGF LRP2 LAMA3 LRP6 LTBP1 SVEP1 TMEFF2	6.06e-11	249	82	13	IPR000742
Domain	EGF-like_CS	SELE SELP FBN1 EFEMP1 TENM4 HMCN2 EGF LRP2 LAMA3 LRP6 LTBP1 SVEP1 TMEFF2	1.09e-10	261	82	13	IPR013032
Domain	EGF	SELE SELP FBN1 EFEMP1 TENM4 EGF LRP2 LAMA3 LRP6 LTBP1 SVEP1 TMEFF2	4.53e-10	235	82	12	SM00181
Domain	Growth_fac_rcpt_	IGF1R FBN1 EFEMP1 HMCN2 EGF ELAPOR1 LRP2 LAMA3 LTBP1 SVEP1	1.58e-09	156	82	10	IPR009030
Domain	EGF	SELE SELP EGF LRP2 LRP6 LTBP1 SVEP1 TMEFF2	8.05e-08	126	82	8	PF00008
Domain	EGF_CA	FBN1 EFEMP1 HMCN2 EGF LRP2 LTBP1 SVEP1	9.85e-08	86	82	7	PF07645
Domain	EGF_Ca-bd_CS	FBN1 EFEMP1 HMCN2 EGF LRP2 LTBP1 SVEP1	2.26e-07	97	82	7	IPR018097
Domain	EGF_CA	FBN1 EFEMP1 HMCN2 EGF LRP2 LTBP1 SVEP1	2.61e-07	99	82	7	PS01187
Domain	ASX_HYDROXYL	FBN1 EFEMP1 HMCN2 EGF LRP2 LTBP1 SVEP1	2.79e-07	100	82	7	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBN1 EFEMP1 HMCN2 EGF LRP2 LTBP1 SVEP1	4.16e-07	106	82	7	IPR000152
Domain	EGF_CA	FBN1 EFEMP1 HMCN2 EGF LRP2 LTBP1 SVEP1	1.08e-06	122	82	7	SM00179
Domain	EGF-like_Ca-bd_dom	FBN1 EFEMP1 HMCN2 EGF LRP2 LTBP1 SVEP1	1.21e-06	124	82	7	IPR001881
Domain	cEGF	FBN1 EFEMP1 LRP2 LTBP1	4.79e-06	26	82	4	IPR026823
Domain	cEGF	FBN1 EFEMP1 LRP2 LTBP1	4.79e-06	26	82	4	PF12662
Domain	-	TENM4 EGF LRP2 LRP6	2.53e-05	39	82	4	2.120.10.30
Domain	Ldl_recept_b	EGF LRP2 LRP6	2.87e-05	14	82	3	PF00058
Domain	LDLRB	EGF LRP2 LRP6	2.87e-05	14	82	3	PS51120
Domain	LY	EGF LRP2 LRP6	3.57e-05	15	82	3	SM00135
Domain	LDLR_classB_rpt	EGF LRP2 LRP6	3.57e-05	15	82	3	IPR000033
Domain	6-blade_b-propeller_TolB-like	TENM4 EGF LRP2 LRP6	4.89e-05	46	82	4	IPR011042
Domain	Selectin_superfamily	SELE SELP	5.70e-05	3	82	2	IPR002396
Domain	HAS/NodC	HAS2 HAS3	5.70e-05	3	82	2	IPR026107
Domain	Sushi	SELE SELP CSMD3 SVEP1	7.96e-05	52	82	4	PF00084
Domain	CCP	SELE SELP CSMD3 SVEP1	9.24e-05	54	82	4	SM00032
Domain	SUSHI	SELE SELP CSMD3 SVEP1	1.07e-04	56	82	4	PS50923
Domain	Sushi_SCR_CCP_dom	SELE SELP CSMD3 SVEP1	1.14e-04	57	82	4	IPR000436
Domain	Ephrin_rec_like	ELAPOR1 SVEP1 TG	1.75e-04	25	82	3	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	ELAPOR1 SVEP1 TG	1.75e-04	25	82	3	IPR011641
Domain	TB	FBN1 LTBP1	3.94e-04	7	82	2	PF00683
Domain	-	FBN1 LTBP1	5.24e-04	8	82	2	3.90.290.10
Domain	TB	FBN1 LTBP1	6.72e-04	9	82	2	PS51364
Domain	TB_dom	FBN1 LTBP1	6.72e-04	9	82	2	IPR017878
Domain	LDLR_class-A_CS	LRP2 LRP6 SSPOP	7.17e-04	40	82	3	IPR023415
Domain	Ldl_recept_a	LRP2 LRP6 SSPOP	1.01e-03	45	82	3	PF00057
Domain	TGc	KY TGM5	1.02e-03	11	82	2	SM00460
Domain	Transglut_core	KY TGM5	1.02e-03	11	82	2	PF01841
Domain	-	EGF SVEP1	1.02e-03	11	82	2	2.40.155.10
Domain	GFP-like	EGF SVEP1	1.02e-03	11	82	2	IPR023413
Domain	Ephrin_rec_like	SVEP1 TG	1.02e-03	11	82	2	PF07699
Domain	Transglutaminase-like	KY TGM5	1.02e-03	11	82	2	IPR002931
Domain	Ig-like_fold	HAVCR2 IGF1R HMCN2 KALRN MYPN VSIG4 PKHD1 IGSF21 USH2A TGM5	1.03e-03	706	82	10	IPR013783
Domain	-	LRP2 LRP6 SSPOP	1.08e-03	46	82	3	4.10.400.10
Domain	LDLRA_1	LRP2 LRP6 SSPOP	1.22e-03	48	82	3	PS01209
Domain	LDLRA_2	LRP2 LRP6 SSPOP	1.30e-03	49	82	3	PS50068
Domain	LDrepeatLR_classA_rpt	LRP2 LRP6 SSPOP	1.30e-03	49	82	3	IPR002172
Domain	LDLa	LRP2 LRP6 SSPOP	1.30e-03	49	82	3	SM00192
Domain	TIL_dom	LRP2 SSPOP	1.67e-03	14	82	2	IPR002919
Domain	Laminin_N	LAMA3 USH2A	2.20e-03	16	82	2	IPR008211
Domain	LAMININ_NTER	LAMA3 USH2A	2.20e-03	16	82	2	PS51117
Domain	Laminin_N	LAMA3 USH2A	2.20e-03	16	82	2	PF00055
Domain	LamNT	LAMA3 USH2A	2.20e-03	16	82	2	SM00136
Domain	EGF_extracell	TENM4 LRP2 SVEP1	2.33e-03	60	82	3	IPR013111
Domain	EGF_2	TENM4 LRP2 SVEP1	2.33e-03	60	82	3	PF07974
Domain	-	HAVCR2 IGF1R KALRN MYPN VSIG4 PKHD1 IGSF21 USH2A TGM5	2.47e-03	663	82	9	2.60.40.10
Domain	AMP-binding_CS	ACSL3 ACSF2	5.78e-03	26	82	2	IPR020845
Domain	-	KLHL24 KLHL21	6.22e-03	27	82	2	2.130.10.80
Domain	AMP_BINDING	ACSL3 ACSF2	6.68e-03	28	82	2	PS00455
Pubmed	Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17.	SELE SELP IL17RA	1.09e-06	9	83	3	15780986
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	FBN1 EFEMP1 HMCN2 LAMA3 LTBP1 COLQ	3.11e-06	167	83	6	22159717
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	FBN1 EFEMP1 HMCN2 LAMA3 LTBP1 SSPOP	4.08e-06	175	83	6	28071719
Pubmed	Anti-P- and E-selectin therapy prevents abortion in the CBA/J x DBA/2J combination by blocking the migration of Th1 lymphocytes into the foetal-maternal interface.	SELE SELP	5.63e-06	2	83	2	16579979
Pubmed	Circulating levels of P-selectin and E-selectin relate to cardiovascular magnetic resonance-derived aortic characteristics in young adults from the general population, a cross-sectional study.	SELE SELP	5.63e-06	2	83	2	30068374
Pubmed	E-selectin and P-selectin expression in endothelium of leprosy skin lesions.	SELE SELP	5.63e-06	2	83	2	26051909
Pubmed	Overlapping roles for endothelial selectins in murine hematopoietic stem/progenitor cell homing to bone marrow.	SELE SELP	5.63e-06	2	83	2	23499761
Pubmed	Complexity within the plasma cell compartment of mice deficient in both E- and P-selectin: implications for plasma cell differentiation.	SELE SELP	5.63e-06	2	83	2	12881311
Pubmed	E-/P-selectins and colon carcinoma metastasis: first in vivo evidence for their crucial role in a clinically relevant model of spontaneous metastasis formation in the lung.	SELE SELP	5.63e-06	2	83	2	20010946
Pubmed	Heterogeneous effect of two selectin gene polymorphisms on coronary artery disease risk: a meta-analysis.	SELE SELP	5.63e-06	2	83	2	24498435
Pubmed	Cloning of the mouse endothelial selectins. Expression of both E- and P-selectin is inducible by tumor necrosis factor alpha.	SELE SELP	5.63e-06	2	83	2	1378846
Pubmed	Angiogenesis in P- and E-selectin-deficient mice.	SELE SELP	5.63e-06	2	83	2	9789257
Pubmed	E- and P-selectins synergistically inhibit bleomycin-induced pulmonary fibrosis.	SELE SELP	5.63e-06	2	83	2	16936251
Pubmed	The N-Terminal Region of Fibrillin-1 Mediates a Bipartite Interaction with LTBP1.	FBN1 LTBP1	5.63e-06	2	83	2	28669633
Pubmed	Hepatocyte growth factor and epidermal growth factor in HIV infected women with preeclampsia.	HGF EGF	5.63e-06	2	83	2	31202974
Pubmed	Inhibition of delayed-type contact hypersensitivity in mice deficient in both E-selectin and P-selectin.	SELE SELP	5.63e-06	2	83	2	8874194
Pubmed	Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins.	SELE SELP	5.63e-06	2	83	2	8647940
Pubmed	Increased soluble selectins as a reflection of activated platelets and endothelium in Legg-Calve-Perthes disease.	SELE SELP	5.63e-06	2	83	2	25000467
Pubmed	Molecular mechanisms underlying IL-4-induced leukocyte recruitment in vivo: a critical role for the alpha 4 integrin.	SELE SELP	5.63e-06	2	83	2	10477616
Pubmed	Coordinated integrin and growth factor regulation of primary keratinocyte migration mediated through extracellular signal regulated kinase and phosphoinositide 3-kinase.	HGF EGF	5.63e-06	2	83	2	19330341
Pubmed	Impaired eosinophil recruitment to the cornea in P-selectin-deficient mice in Onchocerca volvulus keratitis (River blindness).	SELE SELP	5.63e-06	2	83	2	11053286
Pubmed	Contribution of selectin ligands to eosinophil recruitment into the skin of patients with atopic dermatitis.	SELE SELP	5.63e-06	2	83	2	11981814
Pubmed	Phase-dependent roles of E-selectin during chronic contact hypersensitivity responses.	SELE SELP	5.63e-06	2	83	2	17456770
Pubmed	E-selectin gene S128R polymorphism is associated with poor prognosis in patients with stage II or III colorectal cancer.	SELE SELP	5.63e-06	2	83	2	19361981
Pubmed	Migration of activated CD8(+) T lymphocytes to sites of viral infection does not require endothelial selectins.	SELE SELP	5.63e-06	2	83	2	10666212
Pubmed	The anti-inflammatory effects of a selectin ligand mimetic, TBC-1269, are not a result of competitive inhibition of leukocyte rolling in vivo.	SELE SELP	5.63e-06	2	83	2	15466915
Pubmed	Fibulin-3-mediated inhibition of epithelial-to-mesenchymal transition and self-renewal of ALDH+ lung cancer stem cells through IGF1R signaling.	IGF1R EFEMP1	5.63e-06	2	83	2	24013232
Pubmed	Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells.	CLCN5 LRP2	5.63e-06	2	83	2	17369355
Pubmed	A critical temporal window for selectin-dependent CD4+ lymphocyte homing and initiation of late-phase inflammation in contact sensitivity.	SELE SELP	5.63e-06	2	83	2	15117973
Pubmed	Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I.	IGF1R LRP2	5.63e-06	2	83	2	16306401
Pubmed	Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice.	SELE SELP	5.63e-06	2	83	2	8642341
Pubmed	Selectins mediate small cell lung cancer systemic metastasis.	SELE SELP	5.63e-06	2	83	2	24699516
Pubmed	Host defense against systemic infection with Streptococcus pneumoniae is impaired in E-, P-, and E-/P-selectin-deficient mice.	SELE SELP	5.63e-06	2	83	2	9329976
Pubmed	New discoveries with mice mutant in endothelial and platelet selectins.	SELE SELP	5.63e-06	2	83	2	10605793
Pubmed	E- and P-selectin are not required for the development of experimental autoimmune encephalomyelitis in C57BL/6 and SJL mice.	SELE SELP	5.63e-06	2	83	2	18056394
Pubmed	LPA, HGF, and EGF utilize distinct combinations of signaling pathways to promote migration and invasion of MDA-MB-231 breast carcinoma cells.	HGF EGF	5.63e-06	2	83	2	24160245
Pubmed	The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.	HAS2 HAS3	5.63e-06	2	83	2	20507985
Pubmed	Enforced fucosylation of neonatal CD34+ cells generates selectin ligands that enhance the initial interactions with microvessels but not homing to bone marrow.	SELE SELP	5.63e-06	2	83	2	15367439
Pubmed	E and P selectins are not required for resistance to severe murine lyme arthritis.	SELE SELP	5.63e-06	2	83	2	9712820
Pubmed	The selectins E and P in normal labour. A preliminary report on evaluation of their prognostic values for preeclampsia.	SELE SELP	5.63e-06	2	83	2	18217430
Pubmed	Infection-stimulated infraosseus inflammation and bone destruction is increased in P-/E-selectin knockout mice.	SELE SELP	5.63e-06	2	83	2	10447722
Pubmed	Epidermal growth factor promotes stromal cells migration and invasion via up-regulation of hyaluronate synthase 2 and hyaluronan in endometriosis.	EGF HAS2	5.63e-06	2	83	2	32762950
Pubmed	The involvement of the docking protein Gab1 in mitogenic signalling induced by EGF and HGF in rat hepatocytes.	HGF EGF	5.63e-06	2	83	2	24126105
Pubmed	Critical role for caspase-8 in epidermal growth factor signaling.	EGF CASP8	5.63e-06	2	83	2	19470771
Pubmed	Adhesion of small cell lung cancer cells to E- and P-selectin under physiological flow conditions: implications for metastasis formation.	SELE SELP	5.63e-06	2	83	2	21544708
Pubmed	E- and P-selectins are essential for the development of cockroach allergen-induced airway responses.	SELE SELP	5.63e-06	2	83	2	12165540
Pubmed	Serum adhesion molecules in acute pancreatitis: time course and early assessment of disease severity.	SELE SELP	5.63e-06	2	83	2	18580442
Pubmed	Differential expression of E- and P-selectin in the microvasculature of sickle cell transgenic mice.	SELE SELP	5.63e-06	2	83	2	15280076
Pubmed	E and P Selectins as Potential Markers in the Assessment of the Severity of Acute Pancreatitis.	SELE SELP	5.63e-06	2	83	2	29517629
Pubmed	Accelerated development of arthritis in mice lacking endothelial selectins.	SELE SELP	5.63e-06	2	83	2	16207337
Pubmed	Macrophages, not neutrophils, infiltrate skeletal muscle in mice deficient in P/E selectins after mechanical reloading.	SELE SELP	5.63e-06	2	83	2	12829442
Pubmed	Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins.	SELE SELP	5.63e-06	2	83	2	8598043
Pubmed	Overlapping functions of E- and P-selectin in neutrophil recruitment during acute inflammation.	SELE SELP	5.63e-06	2	83	2	9746773
Pubmed	Differential role of E-selectin and P-selectin in T lymphocyte migration to cutaneous inflammatory reactions induced by cytokines.	SELE SELP	5.63e-06	2	83	2	12096034
Pubmed	Regulatory T cells dynamically regulate selectin ligand function during multiple challenge contact hypersensitivity.	SELE SELP	5.63e-06	2	83	2	25274531
Pubmed	Megalin (gp330): a putative endocytic receptor for thyroglobulin (Tg).	LRP2 TG	5.63e-06	2	83	2	9492085
Pubmed	Th1 cell-mediated resistance to cutaneous infection with Leishmania major is independent of P- and E-selectins.	SELE SELP	5.63e-06	2	83	2	14568948
Pubmed	Soluble selectin levels in patients with lung cancer.	SELE SELP	5.63e-06	2	83	2	11936588
Pubmed	Subset-specific reductions in lung lymphocyte accumulation following intratracheal antigen challenge in endothelial selectin-deficient mice.	SELE SELP	5.63e-06	2	83	2	12193727
Pubmed	Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells.	SELE SELP	5.63e-06	2	83	2	15676218
Pubmed	Ser128Arg E-selectin and Thr715Pro P-selectin polymorphisms and severe preeclampsia.	SELE SELP	5.63e-06	2	83	2	17939599
Pubmed	Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment.	SELE SELP	1.69e-05	3	83	2	10500197
Pubmed	Expression of hyaluronan synthase genes in umbilical cord blood stem/progenitor cells.	HAS2 HAS3	1.69e-05	3	83	2	16564133
Pubmed	Maspin, E-selectin, and P-selectin expressions in papillary thyroid carcinomas and their correlation with prognostic parameters.	SELE SELP	1.69e-05	3	83	2	18597952
Pubmed	Mammalian hyaluronan synthases: investigation of functional relationships in vivo.	HAS2 HAS3	1.69e-05	3	83	2	10093717
Pubmed	Selectins influence thrombosis in a mouse model of experimental deep venous thrombosis.	SELE SELP	1.69e-05	3	83	2	12505044
Pubmed	The roles of P- and E-selectins and P-selectin glycoprotein ligand-1 in primary and metastatic mouse melanomas.	SELE SELP	1.69e-05	3	83	2	21889879
Pubmed	Quantifying the effects of molecular orientation and length on two-dimensional receptor-ligand binding kinetics.	SELE SELP	1.69e-05	3	83	2	15299021
Pubmed	Migration induced by epidermal and hepatocyte growth factors in oral squamous carcinoma cells in vitro: role of MEK/ERK, p38 and PI-3 kinase/Akt.	HGF EGF	1.69e-05	3	83	2	22413835
Pubmed	Hyaluronan Regulates Eyelid and Meibomian Gland Morphogenesis.	HAS2 HAS3	1.69e-05	3	83	2	30046813
Pubmed	Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3.	HAS2 HAS3	1.69e-05	3	83	2	25795779
Pubmed	Hyaluronan synthase 1 (HAS1) requires higher cellular UDP-GlcNAc concentration than HAS2 and HAS3.	HAS2 HAS3	1.69e-05	3	83	2	23303191
Pubmed	Selectins: a family of adhesion receptors.	SELE SELP	1.69e-05	3	83	2	1717161
Pubmed	Pathophysiologic importance of E- and L-selectin for neutrophil-induced liver injury during endotoxemia in mice.	SELE SELP	1.69e-05	3	83	2	11050049
Pubmed	Role of primary and secondary capture for leukocyte accumulation in vivo.	SELE SELP	1.69e-05	3	83	2	9440702
Pubmed	L-selectin and E-selectin expressed on monocytes mediating Ehrlichia chaffeensis attachment onto host cells.	SELE SELP	1.69e-05	3	83	2	14592723
Pubmed	Selectin synthesis and inflammation.	SELE SELP	1.69e-05	3	83	2	8851663
Pubmed	Hyaluronan expressed by the hematopoietic microenvironment is required for bone marrow hematopoiesis.	HAS2 HAS3	1.69e-05	3	83	2	22654110
Pubmed	Manipulation of hyaluronan synthase expression in prostate adenocarcinoma cells alters pericellular matrix retention and adhesion to bone marrow endothelial cells.	HAS2 HAS3	1.69e-05	3	83	2	11790779
Pubmed	No detectable endothelial- or leukocyte-derived L-selectin ligand activity on the endothelium in inflamed cremaster muscle venules.	SELE SELP	1.69e-05	3	83	2	18381812
Pubmed	Oxidized low density lipoprotein (LDL) affects hyaluronan synthesis in human aortic smooth muscle cells.	HAS2 HAS3	1.69e-05	3	83	2	23979132
Pubmed	Creation and characterization of E-selectin- and VCAM-1-deficient mice.	SELE SELP	1.69e-05	3	83	2	7587631
Pubmed	Spatiotemporal expression dynamics of selectins govern the sequential extravasation of neutrophils and monocytes in the acute inflammatory response.	SELE SELP	1.69e-05	3	83	2	25722429
Pubmed	Blocking of the interaction between Wnt proteins and their co-receptors contributes to the anti-tumor effects of adenovirus-mediated DKK3 in glioblastoma.	LRP6 DKK3	1.69e-05	3	83	2	25301448
Pubmed	Hepatocyte growth factor, a determinant of airspace homeostasis in the murine lung.	HGF FBN1	1.69e-05	3	83	2	23459311
Pubmed	Activation of bone marrow-resident memory T cells by circulating, antigen-bearing dendritic cells.	SELE SELP	1.69e-05	3	83	2	16155571
Pubmed	Higher-affinity oligosaccharide ligands for E-selectin.	SELE SELP	1.69e-05	3	83	2	7680663
Pubmed	Role of selectins in the triggering, growth, and dissemination of T-lymphoma cells: implication of L-selectin in the growth of thymic lymphoma.	SELE SELP	1.69e-05	3	83	2	15705798
Pubmed	Candidate gene analysis of selectin cluster in patients with multiple sclerosis.	SELE SELP	1.69e-05	3	83	2	19240957
Pubmed	P-selectin glycoprotein ligand-1 contributes to wound healing predominantly as a p-selectin ligand and partly as an e-selectin ligand.	SELE SELP	1.69e-05	3	83	2	19177138
Pubmed	Three vertebrate hyaluronan synthases are expressed during mouse development in distinct spatial and temporal patterns.	HAS2 HAS3	1.69e-05	3	83	2	15765504
Pubmed	Hyaluronan Modulates the Biomechanical Properties of the Cornea.	HAS2 HAS3	1.69e-05	3	83	2	36478198
Pubmed	Cell-cell contact mechanisms.	SELE SELP	1.69e-05	3	83	2	1375831
Pubmed	Hyaluronan Derived From the Limbus is a Key Regulator of Corneal Lymphangiogenesis.	HAS2 HAS3	1.69e-05	3	83	2	30897620
Pubmed	T cell requirement for development of chronic ulcerative dermatitis in E- and P-selectin-deficient mice.	SELE SELP	1.69e-05	3	83	2	12391189
Pubmed	Periprocedural soluble P- and E-selectin levels fail as predictors of clinical restenosis in patients treated with elective coronary stenting.	SELE SELP	1.69e-05	3	83	2	17143564
Pubmed	Imaging molecular expression on vascular endothelial cells by in vivo immunofluorescence microscopy.	SELE SELP	1.69e-05	3	83	2	16779968
Pubmed	In vitro synthesis of hyaluronan by a single protein derived from mouse HAS1 gene and characterization of amino acid residues essential for the activity.	HAS2 HAS3	1.69e-05	3	83	2	10617644
Pubmed	IgG plasma cells display a unique spectrum of leukocyte adhesion and homing molecules.	SELE SELP	1.69e-05	3	83	2	11929781
Pubmed	Expression regulation of hyaluronan synthase in corneal endothelial cells.	HAS2 HAS3	1.69e-05	3	83	2	11006212
Cytoband	1q22-q25	SELE SELP	9.68e-06	3	83	2	1q22-q25
GeneFamily	CD molecules\|Selectins\|Sushi domain containing\|C-type lectin domain containing	SELE SELP	2.82e-05	3	56	2	945
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELE SELP CSMD3 SVEP1	2.89e-05	57	56	4	1179
GeneFamily	Glycosyltransferase family 2	HAS2 HAS3	1.40e-04	6	56	2	428
GeneFamily	Fibulins	EFEMP1 HMCN2	2.61e-04	8	56	2	556
GeneFamily	Low density lipoprotein receptors	LRP2 LRP6	7.19e-04	13	56	2	634
GeneFamily	Acyl-CoA synthetase family	ACSL3 ACSF2	2.92e-03	26	56	2	40
GeneFamily	Zinc fingers CCCH-type	ZC3H7A UNKL	5.25e-03	35	56	2	73
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	IGF1R STYK1	6.82e-03	40	56	2	321
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELE SELP	7.15e-03	41	56	2	1298
GeneFamily	Kelch like\|BTB domain containing	KLHL24 KLHL21	7.49e-03	42	56	2	617
GeneFamily	Fibronectin type III domain containing	IGF1R KALRN USH2A	1.34e-02	160	56	3	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HMCN2 KALRN MYPN	1.36e-02	161	56	3	593
GeneFamily	Adenosine receptors\|V-set domain containing	HAVCR2 VSIG4 IGSF21	1.41e-02	163	56	3	590
GeneFamily	LIM domain containing	NRAP PRICKLE3	1.44e-02	59	56	2	1218
GeneFamily	Olfactory receptors, family 10	OR10H2 OR10H1	1.78e-02	66	56	2	157
GeneFamily	Immunoglobulin like domain containing	HMCN2 VSIG4 IGSF21	2.19e-02	193	56	3	594
Coexpression	NABA_ECM_GLYCOPROTEINS	FBN1 EFEMP1 HMCN2 LAMA3 LTBP1 COLQ USH2A SSPOP SVEP1	1.24e-08	196	83	9	M3008
Coexpression	NABA_ECM_GLYCOPROTEINS	FBN1 EFEMP1 HMCN2 LAMA3 LTBP1 COLQ SSPOP SVEP1	1.70e-07	191	83	8	MM17059
Coexpression	NABA_CORE_MATRISOME	FBN1 EFEMP1 HMCN2 LAMA3 LTBP1 COLQ USH2A SSPOP SVEP1	2.26e-07	275	83	9	M5884
Coexpression	NABA_CORE_MATRISOME	FBN1 EFEMP1 HMCN2 LAMA3 LTBP1 COLQ SSPOP SVEP1	2.31e-06	270	83	8	MM17057
Coexpression	HALLMARK_UV_RESPONSE_DN	IGF1R EFEMP1 KALRN LTBP1 HAS2 NR1D2	6.60e-06	144	83	6	M5942
Coexpression	NABA_MATRISOME	HGF KY FBN1 EFEMP1 HMCN2 EGF LAMA3 LTBP1 COLQ USH2A SSPOP SVEP1 TGM5	1.96e-05	1026	83	13	M5889
Coexpression	HE_LIM_SUN_FETAL_LUNG_C7_FGFBP2_POS_NEURAL_PROGENITOR_CELL	ZNF599 PSMB8 PLA2G6 CCSER1	2.25e-05	52	83	4	M45792
Coexpression	GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_IRES_GFP_UP	KY MYPN LAMA3 RYR1 TG	5.10e-05	126	83	5	M8791
Coexpression	GAO_ESOPHAGUS_25W_C4_FGFR1HIGH_EPITHELIAL_CELLS	FBN1 TENM4 HMCN2 KLHL21 FAM83C SVEP1	5.28e-05	208	83	6	M39139
Coexpression	JEON_SMAD6_TARGETS_UP	FBN1 PSMB8 DKK3	5.91e-05	24	83	3	M4592
Coexpression	LAKE_ADULT_KIDNEY_C13_THICK_ASCENDING_LIMB	IGF1R EGF CLCN5 PKHD1 CCSER1	6.14e-05	131	83	5	M39232
Coexpression	DOUGLAS_BMI1_TARGETS_DN	PLSCR4 KLHL24 EGF JKAMP CASP8 UNKL ZFYVE1	6.31e-05	314	83	7	M14279
Coexpression	NABA_MATRISOME	HGF KY FBN1 EFEMP1 HMCN2 EGF LAMA3 LTBP1 COLQ SSPOP SVEP1 TGM5	7.67e-05	1008	83	12	MM17056
Coexpression	YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0	KLHL24 LAMA3 DKK3 NR1D2	8.16e-05	72	83	4	M15699
Coexpression	GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG2_AND_FOXP3_TRASDUCED_UP	IGF1R EGF ZFP64 PLA2G6 IGSF21	9.60e-05	144	83	5	M9003
Coexpression	YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0	KLHL24 LAMA3 DKK3 NR1D2	1.12e-04	78	83	4	MM867
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500	HGF FBN1 EFEMP1 TENM4 KALRN LTBP1 SVEP1 TMEFF2	1.37e-06	207	82	8	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000	HGF FBN1 EFEMP1 TENM4 KALRN LTBP1 HAS2 SVEP1 TMEFF2	9.03e-06	354	82	9	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_1000	HGF FBN1 TENM4 KALRN LTBP1 HAS2 SVEP1 TMEFF2	2.69e-05	311	82	8	gudmap_dev gonad_e11.5_M_GonMes_Sma_k3_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500	HGF FBN1 EFEMP1 TENM4 KALRN LTBP1 ME1 SVEP1 TMEFF2	3.35e-05	418	82	9	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000	HGF FBN1 EFEMP1 TENM4 KALRN LTBP1 SVEP1 TMEFF2	4.76e-05	337	82	8	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM4 KALRN PKHD1 LRP2 CSMD3 USH2A SSPOP UNC79	2.04e-09	184	83	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM4 KALRN PKHD1 LRP2 CSMD3 USH2A SSPOP UNC79	2.04e-09	184	83	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM4 KALRN PKHD1 LRP2 CSMD3 USH2A SSPOP UNC79	2.04e-09	184	83	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	FBN1 EFEMP1 HMCN2 PSMB8 LTBP1 HAS2 SVEP1 TMEFF2	2.22e-09	186	83	8	e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	DMXL2 NRAP MYPN VSIG4 ME1 TG CCSER1	3.17e-08	170	83	7	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TENM4 VSIG4 PKHD1 LAMA3 IL17RA CSMD3 USH2A	5.87e-08	186	83	7	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	tumor_Lung-Fibroblasts-COL13A1+_matrix_FBs\|tumor_Lung / Location, Cell class and cell subclass	PLSCR4 HGF FBN1 LTBP1 HAS2 DKK3 SVEP1	8.99e-08	198	83	7	2d7842f352273b6b823c86eb548b9f4a4cddf0ae
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 LTBP1 HAS2 SVEP1 TGM5 TMEFF2	8.46e-07	172	83	6	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 EFEMP1 LTBP1 COLQ DKK3 SVEP1	1.18e-06	182	83	6	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 EFEMP1 LTBP1 COLQ DKK3 SVEP1	1.18e-06	182	83	6	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ACSL3 TENM4 KALRN LTBP1 HAS2 ME1	1.18e-06	182	83	6	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CLCN5 PKHD1 LRP2 LAMA3 HAS3 CCSER1	1.33e-06	186	83	6	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	PLSCR4 FBN1 TENM4 LTBP1 DKK3 SVEP1	1.38e-06	187	83	6	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	IGF1R NRAP MYPN LTBP1 COLQ CCSER1	1.42e-06	188	83	6	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 EFEMP1 LTBP1 COLQ DKK3 SVEP1	1.46e-06	189	83	6	324c81285c51f4f8bb1aef428b18fe2c549c2c11
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HGF FBN1 LTBP1 HAS2 DKK3 SVEP1	1.51e-06	190	83	6	2306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HGF FBN1 LTBP1 HAS2 DKK3 SVEP1	1.51e-06	190	83	6	1f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	HGF FBN1 LTBP1 HAS2 DKK3 SVEP1	1.56e-06	191	83	6	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 EFEMP1 LTBP1 COLQ DKK3 SVEP1	1.56e-06	191	83	6	80484d39f34703a33b9bac09826b7a526e883cab
ToppCell	Control-Endothelial-VE_Venous\|Control / Disease state, Lineage and Cell class	PLSCR4 SELE SELP EFEMP1 KALRN DKK3	1.56e-06	191	83	6	617546cf4883dedf3323e03a53ba5adec334cf8e
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 EFEMP1 LTBP1 COLQ DKK3 SVEP1	1.56e-06	191	83	6	d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	HGF FBN1 LTBP1 HAS2 DKK3 SVEP1	1.56e-06	191	83	6	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 EFEMP1 LTBP1 COLQ DKK3 SVEP1	1.56e-06	191	83	6	de3e9b704621b26836c2ddc39fa3e840dfb4541b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLSCR4 HGF FBN1 KALRN LTBP1 SVEP1	1.65e-06	193	83	6	c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLSCR4 HGF FBN1 KALRN LTBP1 SVEP1	1.65e-06	193	83	6	5b602b1702283184bd3943c2a6f2290b7c37e407
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	FBN1 TENM4 LTBP1 HAS2 DKK3 SVEP1	1.70e-06	194	83	6	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	FBN1 EFEMP1 TENM4 HMCN2 HAS2 SVEP1	1.70e-06	194	83	6	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGF FBN1 KALRN LTBP1 DKK3 SVEP1	1.76e-06	195	83	6	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLSCR4 HGF FBN1 KALRN LTBP1 SVEP1	1.76e-06	195	83	6	cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HGF FBN1 EFEMP1 LTBP1 DKK3 SVEP1	1.76e-06	195	83	6	3c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLSCR4 HGF FBN1 KALRN LTBP1 SVEP1	1.76e-06	195	83	6	783bfa8110161cbd6def50ce849cae676c39c458
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGF FBN1 KALRN LTBP1 DKK3 SVEP1	1.76e-06	195	83	6	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLSCR4 HGF FBN1 KALRN LTBP1 SVEP1	1.81e-06	196	83	6	3a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLSCR4 HGF FBN1 KALRN LTBP1 SVEP1	1.81e-06	196	83	6	bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLSCR4 HGF FBN1 KALRN LTBP1 SVEP1	1.86e-06	197	83	6	09946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PKHD1 LRP2 LAMA3 HAS3 ME1 CCSER1	1.86e-06	197	83	6	22b26bac3a99b20c73bfa6e6f81026d064eaa9e8
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	PLSCR4 FBN1 TENM4 KALRN LTBP1 SVEP1	1.86e-06	197	83	6	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGF FBN1 EFEMP1 KALRN LTBP1 SVEP1	1.86e-06	197	83	6	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HGF FBN1 KALRN LTBP1 DKK3 SVEP1	1.86e-06	197	83	6	ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGF FBN1 EFEMP1 KALRN LTBP1 SVEP1	1.86e-06	197	83	6	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HGF FBN1 KALRN LTBP1 DKK3 SVEP1	1.86e-06	197	83	6	37f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell	COPD-Stromal\|COPD / Disease state, Lineage and Cell class	PLSCR4 FBN1 EFEMP1 LTBP1 DKK3 SVEP1	1.86e-06	197	83	6	d5390d86acaa8c39f1da893e8d2271f9ed2951d7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLSCR4 HGF FBN1 KALRN LTBP1 SVEP1	1.92e-06	198	83	6	79576525a10ed3e3a9d1608077cd16ecda23376f
ToppCell	PCW_10-12-Epithelial-Epithelial_airway\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	EFEMP1 ELAPOR1 PKHD1 LRP2 LAMA3 CCSER1	1.92e-06	198	83	6	9a12e5e47236433e512c668005fe3f8be6fde95c
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	HGF FBN1 LTBP1 HAS2 DKK3 SVEP1	1.97e-06	199	83	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	Parenchymal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRODH2 FBN1 MROH8 TENM4 ZFP64 DKK3	1.97e-06	199	83	6	6f5ef959b51eccf1ffc2e5ddf0d83c62ca2257b2
ToppCell	LPS_only-Mesenchymal_fibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	HGF FBN1 LTBP1 HAS2 DKK3 SVEP1	1.97e-06	199	83	6	211c3a08f2d484ab7a3368006767289088f0d957
ToppCell	Parenchymal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRODH2 FBN1 MROH8 TENM4 ZFP64 DKK3	1.97e-06	199	83	6	1aa99d21bf61b86df4a966dc47634044430aa39f
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts\|LPS_only / Treatment groups by lineage, cell group, cell type	HGF FBN1 LTBP1 HAS2 DKK3 SVEP1	1.97e-06	199	83	6	1a0add79f4e34078b3475eb11c85a4234bda197c
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLSCR4 KY FBN1 TENM4 LTBP1 SVEP1	1.97e-06	199	83	6	abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCell	Biopsy_Other_PF-Mesenchymal-Myofibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	HGF FBN1 LTBP1 HAS2 DKK3 SVEP1	2.03e-06	200	83	6	e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	HGF FBN1 LTBP1 HAS2 DKK3 SVEP1	2.03e-06	200	83	6	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	HGF FBN1 LTBP1 HAS2 DKK3 SVEP1	2.03e-06	200	83	6	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	distal-1-mesenchymal\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FBN1 EFEMP1 LTBP1 HAS2 DKK3 SVEP1	2.03e-06	200	83	6	7623f82bd85a0ff7e2097e9281551208dfc602a8
ToppCell	3'-Parenchyma_lung-Mesenchymal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HGF FBN1 EFEMP1 LTBP1 HAS2 SVEP1	2.03e-06	200	83	6	ba5ed66b05caa1be0bbf8d54c4e72a782b8d9833
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	HGF FBN1 LTBP1 HAS2 DKK3 SVEP1	2.03e-06	200	83	6	3bdba9612cd7c612b76aa9abecc4a6529aabfc1c
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HGF FBN1 EFEMP1 LTBP1 HAS2 SVEP1	2.03e-06	200	83	6	2e4ab7fbd94d3d865ef6188d3b4916d2bf1b8d89
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	HGF FBN1 LTBP1 HAS2 DKK3 SVEP1	2.03e-06	200	83	6	44a68bacdb3d5bf563bd35952176995850933a81
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HGF FBN1 EFEMP1 LTBP1 DKK3 SVEP1	2.03e-06	200	83	6	3dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	HGF FBN1 LTBP1 HAS2 DKK3 SVEP1	2.03e-06	200	83	6	dc61016c61729f69649cfb21f6264e685ce83dea
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HGF FBN1 TENM4 LTBP1 HAS2 DKK3	2.03e-06	200	83	6	fb53be20392a8309a7393774c774a1b1aec6e676
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2\|Control_saline / Treatment groups by lineage, cell group, cell type	HGF EFEMP1 SPRY4 LRP6 HAS2 DKK3	2.03e-06	200	83	6	bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HMCN2 KCNH2 ZFP64 SPRY4 FAAH2	9.67e-06	152	83	5	ca23261d8ef263cc697b8d7e7cb2afec8bc564f2
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNH2 ELAPOR1 PKHD1 IGSF21 CCSER1	1.10e-05	156	83	5	58b9520fce6e259b36c3d59e82b712f5e7729e3e
ToppCell	LPS_only-Myeloid-Monocytes,_Macrophages-T-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELP HAVCR2 SF3B4 EGF UNKL	1.17e-05	158	83	5	91d8c93af328c3bbebe1d8f019b94849ebc548c0
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	HMCN2 KCNH2 ZFP64 SPRY4 FAAH2	1.24e-05	160	83	5	19105debef96ea0c267d6a1d332303ec668ae47e
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HAVCR2 GUCY2C PSMB8 SSPOP RYR1	1.28e-05	161	83	5	76c993a4533362db2250c88b3ee3ede55362d54e
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 EFEMP1 MYPN UNKL TMEFF2	1.32e-05	162	83	5	56f1789e69a6cb29956e46aba92b290847327c1f
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 LRP2 CSMD3 USH2A UNC79	1.61e-05	169	83	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PLSCR4 SELE FBN1 TENM4 LTBP1	1.81e-05	173	83	5	1f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SELP HGF PKD1L1 HAS2 DKK3	1.91e-05	175	83	5	90302e8a44858ef3b2a165b88284d4788d591a99
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 LRP2 CSMD3 IGSF21 USH2A	1.91e-05	175	83	5	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	Nasal_Brush-Epithelial-Basal_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	LAMA3 HAS2 HAS3 CSMD3 DKK3	1.96e-05	176	83	5	fc5787946f5a10056d326d070620575ae4081836
ToppCell	Nasal_Brush-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	LAMA3 HAS2 HAS3 CSMD3 DKK3	1.96e-05	176	83	5	5daaba0853afe7d20d4635169ccd4f96e735b938
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	HGF FBN1 LTBP1 DKK3 SVEP1	2.02e-05	177	83	5	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLSCR4 HGF FBN1 LTBP1 SVEP1	2.02e-05	177	83	5	b872ee91e01265b101b81bd304cf6b95d5419e68
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	HGF FBN1 LTBP1 DKK3 SVEP1	2.02e-05	177	83	5	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega\|lymph-node_spleen / Manually curated celltypes from each tissue	SELP EGF KCNH2 LTBP1 MBOAT2	2.13e-05	179	83	5	4e0cf069bc47328eda753a4edc7e89b8915d52bb
ToppCell	Endothelial-B-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	PLSCR4 MROH8 KALRN PRICKLE3 MBOAT2	2.25e-05	181	83	5	4fe0215d08f03d4e24749d70fce01b7aa22906fd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HGF FBN1 SPRY4 HAS2 SVEP1	2.25e-05	181	83	5	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HGF FBN1 SPRY4 HAS2 SVEP1	2.25e-05	181	83	5	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBN1 EFEMP1 LTBP1 COLQ SVEP1	2.31e-05	182	83	5	19c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLSCR4 FBN1 TENM4 LTBP1 SVEP1	2.31e-05	182	83	5	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	Basal\|World / shred by cell class for mouse tongue	KLHL24 EFEMP1 LAMA3 LTBP1 DKK3	2.37e-05	183	83	5	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PKHD1 LRP2 LAMA3 HAS3 CCSER1	2.43e-05	184	83	5	fa4915b0498f3069fd5ef497286445528f75187e
ToppCell	Endothelial-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	PLSCR4 SELE SELP HAS2 DKK3	2.49e-05	185	83	5	ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FBN1 TENM4 HMCN2 LTBP1 SVEP1	2.49e-05	185	83	5	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	HGF FBN1 HMCN2 LTBP1 SVEP1	2.49e-05	185	83	5	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	LPS_only-Epithelial_alveolar-AT_1-AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EFEMP1 PKHD1 LAMA3 ME1 FAAH2	2.49e-05	185	83	5	0c247a3f394c42e2a6f67fee3d9cf33096fecd13
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HGF FBN1 HAS2 DKK3 SVEP1	2.56e-05	186	83	5	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HAVCR2 PRODH2 PKHD1 LRP2 ACSF2	2.56e-05	186	83	5	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	facs-Trachea-nan-24m-Mesenchymal\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 EFEMP1 LTBP1 SVEP1 TMEFF2	2.62e-05	187	83	5	71385068e3fd0bfa7822ae176113a49460c8636b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PLSCR4 SELP EGF KCNH2 LTBP1	2.62e-05	187	83	5	46e15419e80bd7180f3171a99d845b01bb635e53
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PKHD1 LRP2 LAMA3 HAS3 CCSER1	2.62e-05	187	83	5	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	COVID-19-kidney-Mito-rich_Distal\|kidney / Disease (COVID-19 only), tissue and cell type	TENM4 EGF CLCN5 PKHD1 CCSER1	2.62e-05	187	83	5	2ce8038d9d1302e850c1bb536e755598f77ba4b9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HAVCR2 PRODH2 PKHD1 LRP2 ACSF2	2.62e-05	187	83	5	3ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PLSCR4 SELP EGF KCNH2 LTBP1	2.62e-05	187	83	5	0d17b07770e4c881a7ca53a5bd42471457d198fb
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PLSCR4 SELP EGF KCNH2 LTBP1	2.62e-05	187	83	5	69068480f6819a6c8560ecbb05deb156b4055e12
ToppCell	facs-Trachea-nan-24m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 EFEMP1 LTBP1 SVEP1 TMEFF2	2.62e-05	187	83	5	b930d5f7d410ac1f340babec5c937388f64cafc0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PLSCR4 SELP EGF KCNH2 LTBP1	2.62e-05	187	83	5	9c8b932a15b8b50982cba4cf8db750e257eb9503
Disease	glaucoma	EFEMP1 KALRN PKHD1 LTBP1 HERC2	7.16e-05	154	82	5	MONDO_0005041
Disease	Reperfusion Injury	SELE HGF EGF CASP8	1.13e-04	89	82	4	C0035126
Disease	Colorectal Carcinoma	EFEMP1 KALRN GUCY2C PKHD1 LRP2 CASP8 SLC44A4 CSMD3 IGSF21	1.45e-04	702	82	9	C0009402
Disease	hepatocellular carcinoma (is_implicated_in)	HAVCR2 SF3B4 IGF1R EGF CASP8	1.53e-04	181	82	5	DOID:684 (is_implicated_in)
Disease	Goiter	CLCN5 TG	1.59e-04	7	82	2	C0018021
Disease	Adult Hepatocellular Carcinoma	EGF CASP8	2.71e-04	9	82	2	C0279607
Disease	Hernia	KY EFEMP1 HMCN2	3.91e-04	51	82	3	HP_0100790
Disease	body surface area	IGF1R FBN1 EFEMP1 KCNH2 PKHD1 PLA2G6 LTBP1 UNC79	4.21e-04	643	82	8	EFO_0022196
Disease	melanoma	HMCN2 CASP8 PLA2G6 FAM83C	4.29e-04	126	82	4	EFO_0000756
Disease	autoimmune thyroiditis (is_implicated_in)	LRP2 TG	4.94e-04	12	82	2	DOID:7188 (is_implicated_in)
Disease	Congenital myopathy (disorder)	KY RYR1	4.94e-04	12	82	2	C0270960
Disease	diverticular disease	ABHD17A EFEMP1 KCNH2 LTBP1 COLQ	5.19e-04	236	82	5	EFO_0009959
Disease	breast carcinoma	FBN1 SPPL2A NRAP SPRY4 XPNPEP3 CASP8 PLA2G6 IGSF21 DKK3 CCSER1	5.20e-04	1019	82	10	EFO_0000305
Disease	skin pigmentation measurement	FBN1 KALRN HERC2 USH2A	5.88e-04	137	82	4	EFO_0007009
Disease	amino acid measurement	TENM4 GUCY2C STYK1 LRP2 LTBP1 HAS2 TGM5 CCSER1	5.96e-04	678	82	8	EFO_0005134
Disease	body weight	ACSL3 KLHL24 IGF1R EFEMP1 KCNH2 PLA2G6 LTBP1 ZFYVE1 UNC79 TMEFF2 CCSER1	7.21e-04	1261	82	11	EFO_0004338
Disease	amyotrophic lateral sclerosis	EFEMP1 KALRN ZFP64 LAMA3	7.27e-04	145	82	4	MONDO_0004976
Disease	Graves' disease (is_marker_for)	IGF1R TG	7.82e-04	15	82	2	DOID:12361 (is_marker_for)
Disease	birth weight	KLHL24 IGF1R TENM4 PLA2G6 ME1 USH2A	8.68e-04	399	82	6	EFO_0004344
Disease	Nonorganic psychosis	TENM4 KCNH2 PLA2G6	9.50e-04	69	82	3	C0349204
Disease	Paroxysmal atrial fibrillation	SELE IGF1R KCNH2 MYPN	9.54e-04	156	82	4	C0235480
Disease	familial atrial fibrillation	SELE IGF1R KCNH2 MYPN	9.54e-04	156	82	4	C3468561
Disease	Persistent atrial fibrillation	SELE IGF1R KCNH2 MYPN	9.54e-04	156	82	4	C2585653
Disease	Atrial Fibrillation	SELE IGF1R KCNH2 MYPN	1.05e-03	160	82	4	C0004238
Disease	glomerulonephritis (biomarker_via_orthology)	FBN1 LTBP1	1.40e-03	20	82	2	DOID:2921 (biomarker_via_orthology)
Disease	alpha-tocopherol measurement	HGF USH2A	1.40e-03	20	82	2	EFO_0007898
Disease	pulmonary hypertension (biomarker_via_orthology)	HAS2 HAS3 RYR1	1.46e-03	80	82	3	DOID:6432 (biomarker_via_orthology)
Disease	Myocardial Ischemia	SELE SELP HGF PDHA1	1.49e-03	176	82	4	C0151744
Disease	corneal resistance factor	FBN1 EFEMP1 LRP6 LTBP1 HERC2 ZFYVE1	1.62e-03	451	82	6	EFO_0010067
Disease	creatinine measurement	IGF1R SPPL2A MYPN PKHD1 LRP2 PLA2G6 SLC44A4 IGSF21 RYR1	1.76e-03	995	82	9	EFO_0004518
Disease	Sensorineural Hearing Loss (disorder)	DMXL2 LRP2	1.86e-03	23	82	2	C0018784
Disease	systemic scleroderma (is_implicated_in)	HGF FBN1	2.02e-03	24	82	2	DOID:418 (is_implicated_in)
Disease	nevus count, cutaneous melanoma	CASP8 PLA2G6 HERC2	2.11e-03	91	82	3	EFO_0000389, EFO_0004632
Disease	vital capacity	USP14 KY IGF1R EFEMP1 MYPN LRP2 LRP6 LTBP1 DKK3 SVEP1	2.22e-03	1236	82	10	EFO_0004312
Disease	optic disc size measurement	SELP MYPN LRP2 LTBP1	2.59e-03	205	82	4	EFO_0004832

Protein segments in the cluster

Peptide	Gene	Start	Entry
AQMPGRTLYRSLCSC	nan	26	Q6ZS49
NYPIPICLAQCGGAM	CSMD3	2101	Q7Z407
CNIGYLMQGPTKAQC	CSMD3	2901	Q7Z407
CMEGYILSGPSVRQC	CSMD3	3141	Q7Z407
GNRVSCMYVRCVPGA	ABHD17A	96	Q96GS6
NTPGELCIRGYCVML	ACSF2	456	Q96CM8
CAIMSPGKYRLEGQC	CCSER1	316	Q9C0I3
YMPRGSVCNVLLTSC	DMXL2	246	Q8TDJ6
GSQGPRMLRTCYVLC	PRODH2	71	Q9UF12
RMLRTCYVLCSQAGP	PRODH2	76	Q9UF12
PLYGQGELPQCFCRM	CHM	376	P24386
NAQRMGCVLIGPSCT	GUCY2C	111	P25092
PYLLGTMSGCAADCQ	PSMB8	111	P28062
ASIMNAVGCCGLQLY	DPH5	111	Q9H2P9
CLCGPTMNVNNPSYG	COLQ	291	Q9Y215
SCQAQGGCSRPAMVL	IL17RA	761	Q96F46
RYNVLMSPRGCACLV	OR10H2	131	O60403
LYTACGGMNPQECLP	ME1	176	P48163
LGSYQMPCSSVTGQC	LAMA3	541	Q16787
NCNFMGILAGPLCSY	MBOAT2	181	Q6ZWT7
MNVQPCSRCGYGVYP	NRAP	1	Q86VF7
VTCDGCQMFPINGSR	HERC2	2706	O95714
PGQMCFNTRGSYQCV	HMCN2	4916	Q8NDA2
CRLAGVQCMTVPGYS	KY	236	Q8NBH2
MNGVASYCRPCALEA	ELAPOR1	581	Q6UXG2
LCGYSRAEVMQRPCT	KCNH2	51	Q12809
FIRNGSQSMYCIPCE	IGF1R	311	P08069
ENVMRVRGPCSTYGC	PLSCR4	241	Q9NRQ2
CPNGECLNTMGSYRC	LTBP1	636	Q14766
KGPCYRLVSSGRQCM	LTBP1	676	Q14766
CNLMPQDSGIYTCIA	KALRN	2536	O60229
VSGTVYFICQRMLCP	LRP6	1386	O75581
QCTALSNPERGYMNC	SELE	366	P16581
VPNFQRVCGCPYGMR	LRP2	991	P98164
RVCGCPYGMRLASNH	LRP2	996	P98164
NIRVGYCSQIPNCDM	HGF	371	P14210
EIMPNGTCNTECLYR	MROH8	201	Q9H579
GGQRYVMRQSRPHCC	PRICKLE3	286	O43900
ICAGYCPTMTRVLQG	CGB2	51	Q6NT52
MLCNPICGVSYALTV	ICMT	226	O60725
LNGSMYRCTAQNPLG	IGSF21	406	Q96ID5
PMDNCSTTACRGRLY	KLHL21	411	Q9UJP4
NCGMSVCNGKIYILG	KLHL24	536	Q6TFL4
YTCMCAGRLSEPGLI	EGF	936	P01133
LPNMRVRSTCGDTYC	FAM83C	226	Q9BQN1
YRTGPCFTVISNQMC	FBN1	181	P35555
CITPGLYAMVGAAAC	CLCN5	566	P51795
CVQCISGPLGMYRNS	HAS2	276	Q92819
LGMATVNNCVSYRNP	CASP8	401	Q14790
GAQELFLCTGPMCRY	FAAH2	261	Q6GMR7
QCPALTTPGQGTMYC	SELP	641	P16109
SFYVGCAVAMCPNLG	GLIPR1L1	146	Q6UWM5
NSSCPGLMCVFQGYS	SLC44A4	416	Q53GD3
QCISGPLGMYRNSLL	HAS3	281	O00219
YLAGCGLQSCPMLVA	RYR1	2301	P21817
YTCQPCRGQRMLCTR	DKK3	166	Q9UBP4
CVYLPGIQNTMASCS	PKD1L1	2626	Q8TDX9
RYNVLMSPRGCACLV	OR10H1	131	Q9Y4A9
SYLCNTGGRMHLVCP	NR1D2	371	Q14995
FSCMCPQGYQVVRSR	EFEMP1	316	Q12805
SCCGRMPYSTSGNQI	USH2A	3266	O75445
MPYSTSGNQICCAGR	USH2A	3271	O75445
EGVVYNRLPGMFCCG	USH2A	3311	O75445
NRLPGMFCCGQDYVN	USH2A	3316	O75445
QTLVNYGTCMCLVQG	SPRY4	191	Q9C004
QTLCPVMCPGGQEYR	SSPOP	821	A2VEC9
SINMQEPSCRCDAGY	TMEFF2	281	Q9UIK5
GIYCCRIQIPGIMND	HAVCR2	106	Q8TDQ0
CSLINRQMGSCYPIQ	PKHD1	191	P08F94
LCNARCNIMGPNGYP	PLA2G6	241	O60733
GRMCVNCPLGTYYNL	SVEP1	996	Q4LDE5
RFMNICFCCPVGQGY	ACSL3	461	O95573
CSGSCGPIFRANMNT	STYK1	121	Q6J9G0
MTDARNNPYTCTECG	ZNF599	191	Q96NL3
LPCIFICENNRYGMG	PDHA1	216	P08559
YQCLECGQLLMSPSQ	ZNF574	76	Q6ZN55
IPYGQCTIACRGKNM	SPPL2A	271	Q8TCT8
SCPVLCSGNGQYMKG	TENM4	596	Q6N022
YGFTVPQGMRISLQC	VSIG4	151	Q9Y279
MSNGVYCCGPASVRA	TGM5	366	O43548
TKCNDMRQTGYCPRG	UNKL	286	Q9H9P5
GLNPGLMCQESYACS	ZFYVE1	11	Q9HBF4
ICDRYMNGTCPEGNS	ZC3H7A	906	Q8IWR0
SGCMLCSQRRYSLQP	XPNPEP3	21	Q9NQH7
MELPCGLTNLGNTCY	USP14	101	P54578
GPTGSAMQQCQLLCR	TG	1236	P01266
MATLGERTFNCCYPG	ZFP64	291	Q9NTW7
AMNGQYLCNRPITVS	SF3B4	161	Q15427
PGCGTAAMECVRQYI	UNC79	2311	Q9P2D8
MAVDIQPACLGLYCG	JKAMP	1	Q9P055
TYVMPTLIQGLNECC	AK7	686	Q96M32
NYTIMAANPQGRISC	MYPN	1016	Q86TC9