Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	ATP7A ABCA13 VPS4A PEX6 CLPX HELB ACSL1 ABCG4 SHOC1 DNAH5 DNAH8 DYNC1H1 ATP5MGL IPO8 WRN TWNK YTHDC2 ATP10D ABCG1 DNAH17 ATP1A3	2.42e-06	614	211	21	GO:0140657
GeneOntologyMolecularFunction	ATP hydrolysis activity	ATP7A ABCA13 VPS4A PEX6 CLPX HELB ABCG4 SHOC1 DNAH5 DNAH8 DYNC1H1 WRN TWNK YTHDC2 ATP10D ABCG1 ATP1A3	4.87e-06	441	211	17	GO:0016887
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH5 DNAH8 DYNC1H1 DNAH17	3.30e-05	18	211	4	GO:0008569
GeneOntologyMolecularFunction	ABC-type sterol transporter activity	ABCG4 ABCG1	1.11e-04	2	211	2	GO:0034041
GeneOntologyMolecularFunction	D-dopachrome decarboxylase activity	DDT DDTL	1.11e-04	2	211	2	GO:0033981
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ATP7A ABCA13 ABCG4 ATP5MGL IPO8 ABCG1 ATP1A3	1.60e-04	109	211	7	GO:0042626
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH5 DNAH8 DYNC1H1 DNAH17	2.03e-04	28	211	4	GO:0051959
GeneOntologyMolecularFunction	phenylpyruvate tautomerase activity	DDT DDTL	3.31e-04	3	211	2	GO:0050178
GeneOntologyMolecularFunction	steroid binding	CYP11B1 PGR OSBPL2 OSBPL1A NR3C2 ABCG1 ATP1A3	5.38e-04	133	211	7	GO:0005496
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ATP7A ABCA13 VPS4A PEX6 CLPX HELB ABCG4 SHOC1 GNAS DNAH5 DNAH8 DYNC1H1 WRN TWNK YTHDC2 ARHGAP35 ATP10D ABCG1 ATP1A3	5.96e-04	775	211	19	GO:0017111
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH5 DNAH8 DYNC1H1 DNAH17	6.09e-04	37	211	4	GO:0045505
GeneOntologyMolecularFunction	intramolecular oxidoreductase activity, interconverting keto- and enol-groups	DDT DDTL	6.58e-04	4	211	2	GO:0016862
GeneOntologyBiologicalProcess	cholesterol transport	ABCA13 VPS4A SEC24A ABCG4 OSBPL2 TPCN2 SPG11 APOB ABCG1	9.63e-06	134	210	9	GO:0030301
GeneOntologyBiologicalProcess	sterol transport	ABCA13 VPS4A SEC24A ABCG4 OSBPL2 TPCN2 SPG11 APOB ABCG1	1.29e-05	139	210	9	GO:0015918
GeneOntologyCellularComponent	cilium	TMEM67 USP9X SPATA18 PEX6 CDH23 PIK3C3 POC1B STRC CPLANE1 DNAH5 DNAH8 NOTCH2 STRCP1 NPHP1 CFAP47 DNAAF4 TEDC2 RTTN PRAMEF12 ARHGAP35 DNAH17 SPAG17	1.34e-04	898	213	22	GO:0005929
GeneOntologyCellularComponent	outer dynein arm	DNAH5 DNAH8 DNAH17	2.14e-04	12	213	3	GO:0036157
GeneOntologyCellularComponent	9+2 non-motile cilium	CDH23 STRC STRCP1	3.49e-04	14	213	3	GO:0097732
GeneOntologyCellularComponent	kinocilium	CDH23 STRC STRCP1	3.49e-04	14	213	3	GO:0060091
HumanPheno	Functional abnormality of male internal genitalia	TMEM67 MASP1 ATP7A CYP11B1 PEX6 CDH23 NSUN2 RYR1 FANCC FOCAD FANCE STXBP1 NAF1 SHOC1 GNAS STRC HERC2 CAMSAP1 CPLANE1 DNAH5 DNAH8 BICC1 NOTCH2 NPHP1 CFAP47 IPO8 DNAAF4 RTTN WRN SCYL2 PPP2R1A PIEZO2 ZDHHC9 RTL1 DNAH17 SPAG17 VPS13B SEMA3E	1.25e-05	1269	81	38	HP:0000025
HumanPheno	Decreased fertility	CDH23 ZP2 PGR FANCC FANCE SHOC1 GNAS STRC HERC2 DNAH5 DNAH8 NPHP1 CFAP47 DNAAF4 WRN DNAH17 SPAG17 SEMA3E	1.96e-05	380	81	18	HP:0000144
HumanPheno	Abnormal male reproductive system physiology	TMEM67 MASP1 ATP7A CYP11B1 PEX6 CDH23 NSUN2 RYR1 FANCC FOCAD FANCE STXBP1 NAF1 SHOC1 GNAS STRC HERC2 CAMSAP1 CPLANE1 DNAH5 DNAH8 BICC1 NOTCH2 NPHP1 CFAP47 IPO8 DNAAF4 RTTN WRN SCYL2 PPP2R1A PIEZO2 ZDHHC9 RTL1 DNAH17 SPAG17 VPS13B SEMA3E	2.94e-05	1314	81	38	HP:0012874
Domain	ARM-type_fold	USP9X FOCAD PIK3C3 NOC4L GCN1 IPO8 TNPO2 UBR4 RTTN APOB XPO1 SCYL2 PPP2R1A EIF4G1 WDFY3 STAG2	1.36e-06	339	208	16	IPR016024
Domain	AAA	ABCA13 VPS4A PEX6 CLPX ABCG4 DNAH5 DNAH8 DYNC1H1 ABCG1	3.44e-05	144	208	9	SM00382
Domain	AAA+_ATPase	ABCA13 VPS4A PEX6 CLPX ABCG4 DNAH5 DNAH8 DYNC1H1 ABCG1	3.44e-05	144	208	9	IPR003593
Domain	HEAT	PPP4R1L GCN1 TNPO2 XPO1 SCYL2 PPP2R1A	4.44e-05	58	208	6	IPR000357
Domain	ARM-like	USP9X PPP4R1L NOC4L GCN1 IPO8 TNPO2 RTTN XPO1 SCYL2 PPP2R1A WDFY3 STAG2	5.27e-05	270	208	12	IPR011989
Domain	DHC_N1	DNAH5 DNAH8 DYNC1H1	7.32e-05	8	208	3	PF08385
Domain	Dynein_heavy_dom-1	DNAH5 DNAH8 DYNC1H1	7.32e-05	8	208	3	IPR013594
Domain	ABCG1	ABCG4 ABCG1	1.23e-04	2	208	2	IPR020064
Domain	HEAT_REPEAT	PPP4R1L GCN1 TNPO2 XPO1 SCYL2 PPP2R1A	1.29e-04	70	208	6	PS50077
Domain	HEAT	PPP4R1L GCN1 TNPO2 SCYL2 PPP2R1A	1.89e-04	48	208	5	PF02985
Domain	Macrophage_inhib_fac	DDT DDTL	3.68e-04	3	208	2	PD004816
Domain	Macrophage_inhib_fac_CS	DDT DDTL	3.68e-04	3	208	2	IPR019829
Domain	Tautomerase/MIF_sf	DDT DDTL	3.68e-04	3	208	2	IPR014347
Domain	MIF	DDT DDTL	3.68e-04	3	208	2	PS01158
Domain	Macrophage_inhib_fac	DDT DDTL	3.68e-04	3	208	2	IPR001398
Domain	MIF	DDT DDTL	3.68e-04	3	208	2	PF01187
Domain	Dynein_heavy_chain_D4_dom	DNAH5 DNAH8 DYNC1H1	4.53e-04	14	208	3	IPR024317
Domain	Dynein_HC_stalk	DNAH5 DNAH8 DYNC1H1	4.53e-04	14	208	3	IPR024743
Domain	Dynein_heavy_dom-2	DNAH5 DNAH8 DYNC1H1	4.53e-04	14	208	3	IPR013602
Domain	DHC_N2	DNAH5 DNAH8 DYNC1H1	4.53e-04	14	208	3	PF08393
Domain	IMPORTIN_B_NT	IPO8 TNPO2 XPO1	4.53e-04	14	208	3	PS50166
Domain	ATPase_dyneun-rel_AAA	DNAH5 DNAH8 DYNC1H1	4.53e-04	14	208	3	IPR011704
Domain	MT	DNAH5 DNAH8 DYNC1H1	4.53e-04	14	208	3	PF12777
Domain	AAA_8	DNAH5 DNAH8 DYNC1H1	4.53e-04	14	208	3	PF12780
Domain	AAA_5	DNAH5 DNAH8 DYNC1H1	4.53e-04	14	208	3	PF07728
Domain	DHC_fam	DNAH5 DNAH8 DYNC1H1	5.61e-04	15	208	3	IPR026983
Domain	Dynein_heavy	DNAH5 DNAH8 DYNC1H1	5.61e-04	15	208	3	PF03028
Domain	IBN_N	IPO8 TNPO2 XPO1	5.61e-04	15	208	3	PF03810
Domain	Dynein_heavy_dom	DNAH5 DNAH8 DYNC1H1	5.61e-04	15	208	3	IPR004273
Domain	IBN_N	IPO8 TNPO2 XPO1	6.85e-04	16	208	3	SM00913
Domain	FAM47	FAM47A FAM47C	7.30e-04	4	208	2	PF14642
Domain	MAPKKKK	MAP4K3 MAP4K5	7.30e-04	4	208	2	IPR021160
Domain	FAM47	FAM47A FAM47C	7.30e-04	4	208	2	IPR032743
Domain	Importin-beta_N	IPO8 TNPO2 XPO1	8.25e-04	17	208	3	IPR001494
Domain	-	USP9X GCN1 IPO8 TNPO2 RTTN XPO1 SCYL2 PPP2R1A WDFY3	8.82e-04	222	208	9	1.25.10.10
Domain	ABC2_membrane	ABCG4 ABCG1	1.21e-03	5	208	2	PF01061
Domain	ABC_2_trans	ABCG4 ABCG1	1.21e-03	5	208	2	IPR013525
Domain	Sec23/24_helical_dom	SEC24A SEC23B	1.80e-03	6	208	2	IPR006900
Domain	Sec23_24_beta_S	SEC24A SEC23B	1.80e-03	6	208	2	IPR012990
Domain	zf-Sec23_Sec24	SEC24A SEC23B	1.80e-03	6	208	2	PF04810
Domain	Sec23_trunk	SEC24A SEC23B	1.80e-03	6	208	2	PF04811
Domain	Sec23_helical	SEC24A SEC23B	1.80e-03	6	208	2	PF04815
Domain	FAD_binding_1	NDOR1 NOS1	1.80e-03	6	208	2	PF00667
Domain	-	NDOR1 NOS1	1.80e-03	6	208	2	1.20.990.10
Domain	NOL1_NOP2_SUN	NSUN2 NSUN5	1.80e-03	6	208	2	PS01153
Domain	RCMT	NSUN2 NSUN5	1.80e-03	6	208	2	IPR023267
Domain	Sec23_BS	SEC24A SEC23B	1.80e-03	6	208	2	PF08033
Domain	FAD-binding_1	NDOR1 NOS1	1.80e-03	6	208	2	IPR003097
Domain	Sec23/24_trunk_dom	SEC24A SEC23B	1.80e-03	6	208	2	IPR006896
Domain	Znf_Sec23_Sec24	SEC24A SEC23B	1.80e-03	6	208	2	IPR006895
Domain	NADPH_Cyt_P450_Rdtase_dom3	NDOR1 NOS1	1.80e-03	6	208	2	IPR023173
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NDOR1 MED14 PEX6 ZNF236 WNK1 RYR1 FOCAD CHST15 RBM19 A4GALT HERC2 CAMSAP1 GCN1 DYNC1H1 NOTCH2 UBR4 RTTN ZBTB4 TWNK LRRK1 ARHGAP35 HDAC7 TLNRD1 LATS2 BTBD7 EIF4G1 SLC7A5 WDFY3	3.32e-10	1105	216	28	35748872
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	USP9X SEC24A CLPX WNK1 STXBP2 GCN1 DYNC1H1 SEC23B DIP2B MAN2B2 UBR4 XPO1 USP5	2.83e-07	344	216	13	30333137
Pubmed	Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.	CDH23 STRC STRCP1 OTOG	4.61e-07	11	216	4	31776257
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	VPS4A USP9X NSUN2 DDOST DIPK2A AARS2 NUP210 GCN1 DYNC1H1 ADRM1 TUT7 UBR4 XPO1 ANKRD13A PPP2R1A USP5 EIF4G1 SCRIB ATP1A3 STAG2 STOM	5.12e-07	942	216	21	31073040
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	USP9X PSMB5 CLPX EPB41L3 GNAS HERC2 GCN1 UBR4 ANKRD13A USP5 SCRIB STOM	7.04e-07	313	216	12	38270169
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP9X EPB41L3 NSUN2 NUP210 NOC4L HERC2 GCN1 DYNC1H1 SEC23B TUT7 UBR4 YTHDC2 XPO1 PPP2R1A USP5 EIF4G1 STAG2	8.21e-07	653	216	17	22586326
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	MASP1 USP9X CLPX ZNF236 WNK1 NSUN2 DDOST DIPK2A ACSL1 FECH NOC4L GCN1 ADRM1 UBR4 SPG11 XPO1 POLE3 SENP8 TLNRD1 SMG8 BTBD7 EIF4G1 MTBP TMEM68 ATP1A3	9.02e-07	1327	216	25	32694731
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	VPS4A USP9X PSMB5 CLPX NSUN2 DDOST ACSL1 NUP210 FECH GNAS GCN1 DYNC1H1 SEC23B RGPD5 RGPD8 ADRM1 UBR4 XPO1 PPP2R1A NSUN5 OXA1L EIF4G1 SLC7A5 SCRIB	1.20e-06	1257	216	24	37317656
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH5 DNAH8 DYNC1H1 DNAH17	1.38e-06	14	216	4	9373155
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DOCK4 PATZ1 SEC24A SPATA18 EPB41L3 WNK1 PIK3C3 NR3C2 GNAS CAMSAP1 BICC1 SEC23B NOTCH2 DIP2B PRR5 HDAC7 EIF4G1 SCRIB OTOG	2.12e-06	861	216	19	36931259
Pubmed	An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.	CDH23 STRC STRCP1	2.34e-06	5	216	3	24920589
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	USP9X DDOST AARS2 NUP210 NOC4L GCN1 DYNC1H1 IPO8 UBR4 XPO1 SCYL2 PPP2R1A USP5 EIF4G1 SCRIB STAG2	2.81e-06	638	216	16	33239621
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	ATP7A CLPX DDT OSBPL2 HERC2 PIP4P2 NOTCH2 IPO8 ADRM1 MAP4K3 RTTN SCYL2 USP5 OXA1L SLC7A5 SCRIB TMEM68	3.00e-06	719	216	17	35337019
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	ERBB3 ABCA13 PATZ1 CDH23 FBXO24 RBM19 CAMSAP1 CPLANE1 UBR4 YTHDC2 EIF4G1 MTBP	3.10e-06	361	216	12	26167880
Pubmed	HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.	USP9X PSMB5 PBK DDOST OSBPL2 GNAS GCN1 DYNC1H1 SEC23B RGPD5 XPO1 POLE3 PPP2R1A OXA1L SCRIB	3.32e-06	571	216	15	37167062
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	KRT72 VPS4A PSMB5 DDOST AARS2 COG6 NUP210 DYNC1H1 SEC23B IPO8 ADRM1 UBR4 XPO1 ANKRD13A PPP2R1A SCRIB	3.36e-06	647	216	16	26618866
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	INSR CLPX NSUN2 FANCC FANCE FECH POC1B GNAS HERC2 GCN1 DYNC1H1 RGPD5 IPO8 RGPD8 XPO1 PPP2R1A EIF4G1 DIXDC1 SCRIB STAG2 VPS13B STOM	3.57e-06	1155	216	22	20360068
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CPA4 VPS4A PSMB5 CLPX EPB41L3 NSUN2 DDOST ACSL1 RBM19 HERC2 GCN1 DYNC1H1 MAP4K3 TUT7 UBR4 XPO1 SMG8 PPP2R1A USP5 NSUN5 MAP4K5 EIF4G1 WDFY3 SCRIB	4.24e-06	1353	216	24	29467282
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	ERBB3 ATP7A EPB41L3 STXBP1 GNAS NOTCH2 DIP2B LATS2 MAP4K5 SLC7A5 SCRIB STOM	4.82e-06	377	216	12	38117590
Pubmed	Autoregulation of the 26S proteasome by in situ ubiquitination.	PSMB5 HERC2 ADRM1 UBR4	5.21e-06	19	216	4	24743594
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	SEC24A EPB41L3 DDOST GCN1 SEC23B NOTCH2 XPO1 PPP2R1A USP5 EIF4G1 SLC7A5 SCRIB STOM	5.40e-06	449	216	13	31732153
Pubmed	Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.	DDOST NUP210 GCN1 IPO8 APOB XPO1 SLC7A5	7.15e-06	113	216	7	30352685
Pubmed	A role for Piezo2 in EPAC1-dependent mechanical allodynia.	RAPGEF3 SCN9A PIEZO2	8.12e-06	7	216	3	23575686
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH5 DNAH8 DNAH17	8.12e-06	7	216	3	31178125
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	USP9X NSUN2 GCN1 DYNC1H1 DIP2B UBR4 XPO1 PPP2R1A USP5 EIF4G1 STAG2	8.27e-06	332	216	11	32786267
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	TDRD15 ATP7A SEC24A INSR EPB41L3 OSBPL2 RBM19 CAMSAP1 GCN1 DYNC1H1 SEC23B NOTCH2 WRN APOB SLC7A5 SCRIB STOM	8.31e-06	777	216	17	35844135
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	USP9X SEC24A PSMB5 PBK CLPX WNK1 NSUN2 WARS2 DDOST RBM19 NAF1 GCN1 DYNC1H1 SEC23B UBR4 XPO1 ARHGAP35 SLC1A3 PPP2R1A USP5 OXA1L EIF4G1 SLC7A5 STAG2	8.96e-06	1415	216	24	28515276
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	VPS4A USP9X PSMB5 SPATA18 CLPX EPB41L3 NSUN2 DDOST RBM19 NUP210 NOC4L GNAS DNAH5 GCN1 DYNC1H1 IPO8 UBR4 YTHDC2 APOB XPO1 PPP2R1A EIF4G1 SLC7A5 STAG2	1.01e-05	1425	216	24	30948266
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	VPS4A PSMB5 CLPX NSUN2 DDOST AARS2 COG6 NUP210 NOC4L GNAS GCN1 DYNC1H1 IPO8 TNPO2 UBR4 YTHDC2 XPO1 ANKRD13A PPP2R1A USP5 EIF4G1 SLC7A5 SCRIB STAG2	1.19e-05	1440	216	24	30833792
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KRT72 ZNF174 CLPX EPB41L3 STXBP1 STXBP2 FAM186A SCN9A DNAH8 ERICH6 RGPD5 RGPD8 UBR4 TWNK SPG11 APOB PRX LATS2 EIF4G1 PCDHGB4 SLC7A5 ATP1A3 SPAG17 STAG2	1.22e-05	1442	216	24	35575683
Pubmed	Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.	CDH23 STRC STRCP1	1.29e-05	8	216	3	21165971
Pubmed	Variants in the 1q21 risk region are associated with a visual endophenotype of autism and schizophrenia.	OR6C76 OR6C3 OR6C65 OR6C4	1.39e-05	24	216	4	24152035
Pubmed	Defining the membrane proteome of NK cells.	ATP7A USP9X MED14 DDOST ACSL1 PIK3C3 RBM19 NUP210 GNAS HERC2 GCN1 DYNC1H1 NOTCH2 DIP2B UBR4 XPO1 EIF4G1 SLC7A5 IL2RB STAG2 STOM	1.43e-05	1168	216	21	19946888
Pubmed	Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.	USP9X WNK1 PDLIM3 HERC2 TPCN2 ZDHHC9	1.45e-05	84	216	6	15203218
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ATP7A INSR ITGA7 STXBP1 NOTCH2 NPHP1 MAP4K3 PRR5 MAP4K5 LRRC1 SLC7A5 SCRIB	1.45e-05	421	216	12	36976175
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	PSMB5 EPB41L3 DDOST PIK3C3 RBM19 ADRM1 TUT7 RTTN APOB SCYL2 USP5 OXA1L LRRC1	1.55e-05	496	216	13	31343991
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	USP9X DDOST NUP210 HERC2 GCN1 IPO8 ADRM1 UBR4 XPO1 SLC1A3 ANKRD13A PPP2R1A OXA1L SLC7A5 STOM	1.75e-05	657	216	15	36180527
Pubmed	Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.	NSUN2 HELB HERC2 XPO1 PPP2R1A USP5	1.78e-05	87	216	6	17148452
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	USP9X COG6 GCN1 IPO8 TNPO2 XPO1 ANKRD13A PPP2R1A	2.05e-05	183	216	8	23956138
Pubmed	Functional proteomics mapping of a human signaling pathway.	USP25 PEX6 RBM19 HERC2 CAMSAP1 DYNC1H1 NOTCH2 UBR4 TWNK SCYL2 ANKRD13A PPP2R1A USP5 EIF4G1	2.24e-05	591	216	14	15231748
Pubmed	Evidence that the transcriptional repressor ICER is regulated via the N-end rule for ubiquitination.	PSMB5 GCN1 DYNC1H1 UBR4	2.64e-05	28	216	4	35227662
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	PATZ1 VPS4A CDH23 WNK1 ACSL1 NAF1 FECH OSBPL1A GCN1 PIP4P2 DYNC1H1 NPHP1 IPO8 ADRM1 DNAAF4 WRN HDAC7 SCYL2 ANKRD13A PPP2R1A OXA1L STOM	2.85e-05	1321	216	22	27173435
Pubmed	Isolation of human proteasomes and putative proteasome-interacting proteins using a novel affinity chromatography method.	PSMB5 USP25 ADRM1 UBR4 USP5	3.09e-05	58	216	5	19013454
Pubmed	The genetics of nodal marginal zone lymphoma.	PTPRD NOTCH2	3.84e-05	2	216	2	27335277
Pubmed	Exome sequencing in four families with neurodevelopmental disorders: genotype-phenotype correlation and identification of novel disease-causing variants in VPS13B and RELN.	RELN VPS13B	3.84e-05	2	216	2	38771357
Pubmed	The coexpression of reelin and neuronal nitric oxide synthase in a subpopulation of dentate gyrus neurons is downregulated in heterozygous reeler mice.	RELN NOS1	3.84e-05	2	216	2	21331324
Pubmed	Regulation of the Fanconi anemia group C protein through proteolytic modification.	FANCC FANCE	3.84e-05	2	216	2	14625294
Pubmed	Variable phenotype of del45-55 Becker patients correlated with nNOSμ mislocalization and RYR1 hypernitrosylation.	RYR1 NOS1	3.84e-05	2	216	2	22589245
Pubmed	Identification of rare missense mutations in NOTCH2 and HERC2 associated with familial central precocious puberty via whole-exome sequencing.	HERC2 NOTCH2	3.84e-05	2	216	2	32400230
Pubmed	Distribution maps of D-dopachrome tautomerase in the mouse brain.	DDT DDTL	3.84e-05	2	216	2	23000624
Pubmed	Functional Cooperativity between ABCG4 and ABCG1 Isoforms.	ABCG4 ABCG1	3.84e-05	2	216	2	27228027
Pubmed	Electroacupuncture Attenuates Post-Inflammatory IBS-Associated Visceral and Somatic Hypersensitivity and Correlates With the Regulatory Mechanism of Epac1-Piezo2 Axis.	RAPGEF3 PIEZO2	3.84e-05	2	216	2	35865309
Pubmed	Glucocorticoid and mineralocorticoid cross-talk with progesterone receptor to induce focal adhesion and growth inhibition in breast cancer cells.	PGR NR3C2	3.84e-05	2	216	2	14617569
Pubmed	Munc18-1 and Munc18-2 proteins modulate beta-cell Ca2+ sensitivity and kinetics of insulin exocytosis differently.	STXBP1 STXBP2	3.84e-05	2	216	2	21690086
Pubmed	LXR-induced redistribution of ABCG1 to plasma membrane in macrophages enhances cholesterol mass efflux to HDL.	ABCG4 ABCG1	3.84e-05	2	216	2	16556852
Pubmed	ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain.	ABCG4 ABCG1	3.84e-05	2	216	2	18039927
Pubmed	Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications for heterodimerization.	ABCG4 ABCG1	3.84e-05	2	216	2	15240127
Pubmed	Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport.	OSBPL2 OSBPL1A	3.84e-05	2	216	2	11279184
Pubmed	Chlorambucil-induced mutations in mice recovered in homozygotes.	RELN BICC1	3.84e-05	2	216	2	1557392
Pubmed	Bi-Allelic Mutations in STXBP2 Reveal a Complementary Role for STXBP1 in Cytotoxic Lymphocyte Killing.	STXBP1 STXBP2	3.84e-05	2	216	2	29599780
Pubmed	Crucial role of the hydrophobic pocket region of Munc18 protein in mast cell degranulation.	STXBP1 STXBP2	3.84e-05	2	216	2	23487749
Pubmed	The Tumor Suppressor SCRIB is a Negative Modulator of the Wnt/β-Catenin Signaling Pathway.	LRRC1 SCRIB	3.84e-05	2	216	2	31513346
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	3.84e-05	2	216	2	34910522
Pubmed	Cloning of the mouse gene for D-dopachrome tautomerase.	DDT DDTL	3.84e-05	2	216	2	9858785
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	3.84e-05	2	216	2	11687802
Pubmed	The N-peptide-binding mode is critical to Munc18-1 function in synaptic exocytosis.	STXBP1 STXBP2	3.84e-05	2	216	2	30275014
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	TMEM67 CPLANE1 DNAH5 BICC1 DNAAF4 WRN	3.93e-05	100	216	6	25807483
Pubmed	A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein.	DYNC1H1 YTHDC2 PPP2R1A SCRIB PLCE1	3.96e-05	61	216	5	19875381
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ATP7A USP9X SEC24A EPB41L3 DDOST CAMSAP1 GCN1 DYNC1H1 YTHDC2 XPO1 SCYL2 PPP2R1A MAP4K5 EIF4G1 SCRIB	4.12e-05	708	216	15	39231216
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	C5orf22 PSMB5 DDOST ACSL1 PTPRD NUP210 GNAS GCN1 DIP2B IPO8 ADRM1 UBR4 YTHDC2 XPO1 ANKRD13A PPP2R1A USP5 LRRC1	4.22e-05	974	216	18	28675297
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	MED14 EPB41L3 ZP2 RYR1 FASTK MAP4K3 PCDHA3 TLR9 PRX MAP4K5	4.43e-05	329	216	10	17474147
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	PDE3A USP9X PSMB5 NSUN2 DDOST GCN1 DYNC1H1 UBR4 XPO1 PPP2R1A LATS2	4.48e-05	399	216	11	37536630
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	USP9X DDOST NUP210 GCN1 IPO8 ADRM1 UBR4 XPO1 SLC1A3 PPP2R1A STOM	5.47e-05	408	216	11	33766124
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	RELN ERBB3 USP9X ZBTB43 USP25 NSUN2 FOCAD STXBP1 PTPRD OSBPL1A HERC2 PIP4P2 UAP1L1 DYNC1H1 TNPO2 UBR4 ZBTB4 SCYL2 EIF4G1 WDFY3 SCRIB	5.71e-05	1285	216	21	35914814
Pubmed	Joubert Syndrome	TMEM67 POC1B CPLANE1 NPHP1	5.80e-05	34	216	4	20301500
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	ERBB3 PSMB5 PEX6 CLPX NSUN2 DDOST SEC23B DIP2B TUT7 YTHDC2 SMG8 SCRIB SEMA3E PLCE1	6.25e-05	650	216	14	38777146
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	SEC24A PSMB5 PEX6 CLPX WARS2 DDOST AARS2 FECH NOC4L GNAS HERC2 SEC23B DIP2B IPO8 RGPD8 TUT7 UBR4 TWNK YTHDC2 SCYL2 OXA1L VPS13B STOM	6.34e-05	1496	216	23	32877691
Pubmed	The finished DNA sequence of human chromosome 12.	WNK1 FAM186A GCN1 OR6C3 HDAC7	7.18e-05	69	216	5	16541075
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	USP9X STXBP1 GNAS DYNC1H1 ATP5MGL RGPD8 ADRM1 UBR4 XPO1 PPP2R1A EIF4G1 SLC7A5 ATP1A3 STOM	7.96e-05	665	216	14	30457570
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	USP9X INSR NSUN2 DDOST STXBP2 AARS2 NUP210 NOC4L GNAS HERC2 GCN1 DYNC1H1 YTHDC2 XPO1 PPP2R1A EIF4G1 SCRIB STAG2	7.97e-05	1024	216	18	24711643
Pubmed	The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.	USP9X HERC2 UBR4	8.18e-05	14	216	3	27626314
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	TDRD15 USP9X PSMB5 CLPX DDOST GCN1 DYNC1H1 SEC23B RGPD5 RGPD8 UBR4 XPO1 PPP2R1A EIF4G1 TNS4 IL2RB	8.46e-05	844	216	16	25963833
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	MED14 NSUN2 DDOST PIK3C3 NOC4L HERC2 GCN1 IPO8 TUT7 WRN TWNK YTHDC2 XPO1 NSUN5 EIF4G1	8.95e-05	759	216	15	35915203
Pubmed	IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.	USP9X PSMB5 DYNC1H1	1.02e-04	15	216	3	18303054
Pubmed	Periovulatory insulin signaling is essential for ovulation, granulosa cell differentiation, and female fertility.	INSR PGR	1.15e-04	3	216	2	31908002
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	1.15e-04	3	216	2	30801007
Pubmed	Kidney function in mice lacking aldosterone.	CYP11B1 NR3C2	1.15e-04	3	216	2	16118390
Pubmed	Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9.	PIK3C3 TLR9	1.15e-04	3	216	2	14751759
Pubmed	Molecular identification of two novel Munc-18 isoforms expressed in non-neuronal tissues.	STXBP1 STXBP2	1.15e-04	3	216	2	7890715
Pubmed	Single-nucleotide polymorphisms inside microRNA target sites influence the susceptibility to type 2 diabetes.	INSR ACSL1	1.15e-04	3	216	2	23303383
Pubmed	Scribble promotes alveologenesis in the pregnant mammary gland for milk production.	PGR SCRIB	1.15e-04	3	216	2	32213656
Pubmed	Aldosterone postnatally, but not at birth, is required for optimal induction of renal mineralocorticoid receptor expression and sodium reabsorption.	CYP11B1 NR3C2	1.15e-04	3	216	2	21467193
Pubmed	Astrocytic insulin receptor controls circadian behavior via dopamine signaling in a sexually dimorphic manner.	INSR SLC1A3	1.15e-04	3	216	2	38071352
Pubmed	The nuclear accumulation of the Fanconi anemia protein FANCE depends on FANCC.	FANCC FANCE	1.15e-04	3	216	2	16513431
Pubmed	The Epac-Phospholipase Cε Pathway Regulates Endocannabinoid Signaling and Cocaine-Induced Disinhibition of Ventral Tegmental Area Dopamine Neurons.	RAPGEF3 PLCE1	1.15e-04	3	216	2	28209735
Pubmed	Genetic regulation of gene expression of MIF family members in lung tissue.	DDT DDTL	1.15e-04	3	216	2	33046825
Pubmed	[The association of polymorphisms in SLC18A1, TPH1 and RELN genes with risk of paranoid schizophrenia].	RELN SLC18A1	1.15e-04	3	216	2	25842846
Pubmed	HERC2 inactivation abrogates nucleolar localization of RecQ helicases BLM and WRN.	HERC2 WRN	1.15e-04	3	216	2	33432007
Pubmed	The Insulin Receptor and Insulin like Growth Factor Receptor 5' UTRs Support Translation Initiation Independently of EIF4G1.	INSR EIF4G1	1.15e-04	3	216	2	37724583
Pubmed	Epac1 and Epac2 are differentially involved in inflammatory and remodeling processes induced by cigarette smoke.	RAPGEF3 PLCE1	1.15e-04	3	216	2	25103224
Interaction	TOP3B interactions	NDOR1 SEC24A MED14 PEX6 CLPX ZNF236 WNK1 RYR1 FOCAD CHST15 FASTK RBM19 A4GALT GNAS HERC2 CAMSAP1 GCN1 DYNC1H1 SEC23B NOTCH2 UBR4 RTTN ZBTB4 WRN TWNK APOB LRRK1 ARHGAP35 HDAC7 TLNRD1 LATS2 BTBD7 EIF4G1 SLC7A5 WDFY3	2.26e-06	1470	206	35	int:TOP3B
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	KRT72 ERBB3 ITGA7 RAPGEF3 FAM186A OR6C76 DIP2B OR6C3 OR6C65 HDAC7 OR6C4	6.38e-06	423	217	11	chr12q13
Cytoband	12q13.2	OR6C76 OR6C3 OR6C65 OR6C4	1.37e-04	55	217	4	12q13.2
Cytoband	6p12.1	KIAA1586 GSTA2 LRRC1	5.12e-04	33	217	3	6p12.1
Cytoband	Xp21.1	FAM47A FAM47C CFAP47	5.59e-04	34	217	3	Xp21.1
Cytoband	7q22	RELN MUC3B FBXO24	7.78e-04	38	217	3	7q22
Cytoband	15q13	HERC2 TLNRD1	7.83e-04	9	217	2	15q13
GeneFamily	Dyneins, axonemal	DNAH5 DNAH8 DNAH17	2.91e-04	17	141	3	536
GeneFamily	Cadherin related	CDHR2 CDH23 FAT3	2.91e-04	17	141	3	24
GeneFamily	Blood group antigens\|CD molecules\|ATP binding cassette subfamily G	ABCG4 ABCG1	5.95e-04	5	141	2	811
GeneFamily	Mitogen-activated protein kinase kinase kinase kinases	MAP4K3 MAP4K5	5.95e-04	5	141	2	655
GeneFamily	Olfactory receptors, family 6	OR6C76 OR6C3 OR6C65 OR6C4	6.67e-04	51	141	4	153
GeneFamily	NOP2/Sun RNA methyltransferase family	NSUN2 NSUN5	1.24e-03	7	141	2	664
Coexpression	GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_UP	EPB41L3 ACSL1 ABCG4 CRISPLD1 WRN SPG11 LRRK1 RLN1 ABCG1 PLCE1	5.73e-06	200	212	10	M4353
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000	PDE3A USP9X INSR MED14 EPB41L3 HERC2 CPLANE1 GCN1 IPO8 FAT3 WRN SCYL2 ULBP1 VPS13B	1.02e-05	369	198	14	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000	USP9X INSR MED14 EPB41L3 WNK1 HERC2 CAMSAP1 CPLANE1 GCN1 IPO8 FAT3 SENP8 EIF4G1 VPS13B	1.64e-05	385	198	14	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlas	DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#5_top-relative-expression-ranked_1000	C5orf22 USP9X MED14 CPLANE1 FAT3 ZBTB4 LRRK1 SENP8 LATS2 DIXDC1	2.00e-05	201	198	10	gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000	PDE3A USP9X INSR MED14 EPB41L3 DIPK2A MFAP3 PTPRD PDLIM3 HERC2 CPLANE1 GCN1 CRISPLD1 IPO8 FAT3 WRN SCYL2 ARHGAP6 ULBP1 VPS13B SEMA3E	2.22e-05	806	198	21	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#5_top-relative-expression-ranked_500	PDE3A USP9X INSR EPB41L3 HERC2 CPLANE1 GCN1 FAT3 SCYL2	8.96e-05	194	198	9	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k5_500
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ABCA13 PTPRD SCN9A DNAH5 FAT3 APOB PIEZO2 SPAG17 OTOG PLCE1	1.61e-09	184	214	11	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ABCA13 PTPRD SCN9A DNAH5 FAT3 APOB PIEZO2 SPAG17 OTOG PLCE1	1.61e-09	184	214	11	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ABCA13 PTPRD SCN9A DNAH5 FAT3 APOB PIEZO2 SPAG17 OTOG PLCE1	1.61e-09	184	214	11	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	KRT72 PGR CAMSAP1 RGPD5 MAP4K3 DNAAF4 RTTN RLN1 ZDHHC9 EIF4G1	5.87e-09	160	214	10	19105debef96ea0c267d6a1d332303ec668ae47e
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PTPRD PDLIM3 MRC2 BICC1 FAT3 SLC1A3 ARHGAP6 PIEZO2	4.01e-07	192	214	9	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PTPRD PDLIM3 MRC2 BICC1 FAT3 SLC1A3 ARHGAP6 PIEZO2	4.38e-07	194	214	9	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KRT72 PGR CAMSAP1 RGPD5 MAP4K3 RTTN RLN1 EIF4G1	7.49e-07	152	214	8	ca23261d8ef263cc697b8d7e7cb2afec8bc564f2
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PTPRD MRC2 BICC1 FAT3 SLC1A3 ARHGAP6 PIEZO2	3.82e-06	189	214	8	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MASP1 RAPGEF3 A4GALT PRX ARHGAP6 LRRN3 PIEZO2 ZDHHC9	3.82e-06	189	214	8	09dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PTPRD MRC2 BICC1 FAT3 SLC1A3 ARHGAP6 PIEZO2	3.97e-06	190	214	8	841cd55861b43578d704418b9bc0af2e8b88323a
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PTPRD MRC2 BICC1 FAT3 SLC1A3 ARHGAP6 PIEZO2	4.13e-06	191	214	8	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PTPRD MRC2 BICC1 FAT3 SLC1A3 ARHGAP6 PIEZO2	4.29e-06	192	214	8	6f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN PDE3A B4GALT6 NR3C2 GNAS KMO ATP1A3 PLCE1	4.29e-06	192	214	8	025fac36b862f9ca7f96fb4a1946c44ba7cbc382
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PTPRD MRC2 BICC1 FAT3 SLC1A3 ARHGAP6 PIEZO2	4.29e-06	192	214	8	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PTPRD PDLIM3 BICC1 FAT3 SLC1A3 ARHGAP6 PIEZO2	4.29e-06	192	214	8	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PTPRD MRC2 BICC1 FAT3 SLC1A3 ARHGAP6 PIEZO2	4.29e-06	192	214	8	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PTPRD MRC2 BICC1 FAT3 SLC1A3 ARHGAP6 PIEZO2	4.46e-06	193	214	8	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PTPRD MRC2 BICC1 FAT3 SLC1A3 ARHGAP6 PIEZO2	4.63e-06	194	214	8	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 ABCA13 SHOC1 DNAH5 NPHP1 CFAP47 DNAAF4 SPAG17	4.63e-06	194	214	8	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PTPRD MRC2 BICC1 FAT3 SLC1A3 ARHGAP6 PIEZO2	4.63e-06	194	214	8	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ITGA7 PGR FBXO24 PTPRD PDLIM3 PCDHA3 PIEZO2 PCDHGB4	5.00e-06	196	214	8	614a07334707eafe238d5cb7b080a3ca796a1920
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 CCDC81 CPLANE1 DNAH5 NPHP1 CFAP47 DNAAF4 SPAG17	5.19e-06	197	214	8	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	KRT72 HELB CAMSAP1 RGPD5 PIM2 RTTN RLN1	8.63e-06	151	214	7	72c47ed207951e73ef6c72085b2a3f48a99be952
ToppCell	3'_v3-blood-Lymphocytic_Invariant-Inducer-like-ILC3\|blood / Manually curated celltypes from each tissue	NFILZ PTPRD OSBPL1A BICC1 FAT3 KMO ATP10D	1.11e-05	157	214	7	eb2520c237543ea4869d4386afc0457b111f6193
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TDRD15 CHST15 FAM186A NUP210 PIM2 LRRK1 SLC7A5	1.16e-05	158	214	7	6b51e5ee08e23924f5edbaf0a845a9232fb7ff7a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TDRD15 CHST15 FAM186A NUP210 PIM2 LRRK1 SLC7A5	1.16e-05	158	214	7	8dd83a2a4c2ec9cdc3a03df8b51ee22bee1c2888
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PBK SENP8 SMG8 ULBP1 SLC7A5 MTBP TNS4	1.73e-05	168	214	7	9b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic-cDC1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PBK SENP8 SMG8 ULBP1 SLC7A5 MTBP TNS4	1.73e-05	168	214	7	4b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PBK SENP8 SMG8 ULBP1 SLC7A5 MTBP TNS4	1.73e-05	168	214	7	c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN PDLIM3 CHST15 EXOC3L1 ABCG1 PIEZO2 CCM2L	2.33e-05	176	214	7	5d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCell	15-Airway-Epithelial-Multiciliated_precursor\|Airway / Age, Tissue, Lineage and Cell class	SPATA18 DNAH5 PIM2 DNAAF4 RLN1 DNAH17 SPAG17	2.50e-05	178	214	7	d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN ZP2 A4GALT EXOC3L1 ABCG1 CCM2L OR6C4	2.50e-05	178	214	7	4ef6344d0ffc9c55b1240bee94b741382f1427bb
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN ZP2 A4GALT EXOC3L1 ABCG1 CCM2L OR6C4	2.50e-05	178	214	7	c65932cbedbbfacb6f0299280663fe7c88dba72b
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDHR2 FAM217A DIPK2A SYT6 SLC35G2 LRRN3 SEMA3E	2.59e-05	179	214	7	7c8a2fa1326c73dc9e774df645b572864fd97133
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PTPRD BICC1 FAT3 ITPRID1 SLC1A3 PIEZO2	2.69e-05	180	214	7	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PTPRD BICC1 FAT3 ITPRID1 SLC1A3 PIEZO2	2.69e-05	180	214	7	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ndnf_(medial_geniculate_nucleus,_ventral_part_(MGV)?_Or_State?)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	C1orf105 EXOC3L1 PRX RLN1 SLC18A1	2.87e-05	74	214	5	195fd37345a394c0b60f713bedadf6fd08dc050c
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ndnf_(medial_geniculate_nucleus,_ventral_part_(MGV)?_Or_State?)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	C1orf105 EXOC3L1 PRX RLN1 SLC18A1	2.87e-05	74	214	5	c68b00cf7d2cec7951b78e2c6710d7770b02566a
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ndnf_(medial_geniculate_nucleus,_ventral_part_(MGV)?_Or_State?)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	C1orf105 EXOC3L1 PRX RLN1 SLC18A1	2.87e-05	74	214	5	bad24c9251ef44c05f3390073732a467aaeefe1e
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCAR1 MRC2 PRX PIEZO2 PCDHGB4 SEMA3E PLCE1	3.09e-05	184	214	7	1c857126c0ea0671f0d60b048efca288d348d653
ToppCell	18-Distal-Epithelial-Multiciliated_precursor\|Distal / Age, Tissue, Lineage and Cell class	SPATA18 CCDC81 NPHP1 CFAP47 PIM2 DNAAF4 SPAG17	3.31e-05	186	214	7	58ab1360a1730655a5939295ba05997ac4a2d14e
ToppCell	saliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PSMB5 USP25 GCN1 HDAC7 PRX TDRD7 TLNRD1	3.43e-05	187	214	7	43ef900b76f3c38bd8ce9858201124130c743d56
ToppCell	saliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PSMB5 USP25 GCN1 HDAC7 PRX TDRD7 TLNRD1	3.43e-05	187	214	7	6e5c38425b6b1d4774f8dcea7e146f1eab785c3e
ToppCell	Control-Epithelial-Ciliated\|Control / Disease state, Lineage and Cell class	TMEM67 ABCA13 SPATA18 DNAH5 CFAP47 GSTA2 SPAG17	3.67e-05	189	214	7	c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK4 PGR PTPRD FAT3 SLC1A3 ARHGAP6 PIEZO2	3.67e-05	189	214	7	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PDE3A PGR BICC1 SYT6 SLC1A3 PIEZO2 SEMA3E	3.92e-05	191	214	7	fa380a8752de158974b2ae5e741573439719cc0d
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	INSR EPB41L3 PTPRD BICC1 DIP2B ARHGAP6 VPS13B	4.06e-05	192	214	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	LPS-IL1RA-Stromal_mesenchymal\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A PDLIM3 MRC2 BICC1 FAT3 SLC1A3 PIEZO2	4.06e-05	192	214	7	4e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP9X INSR CHST15 HERC2 UBR4 PIEZO2 BTBD7	4.06e-05	192	214	7	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK4 PGR PTPRD BICC1 SLC1A3 PIEZO2 SEMA3E	4.19e-05	193	214	7	9f69edc97b868d23998abc98928a2e89a885ef8a
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	TMEM67 ABCA13 SPATA18 DNAH5 BICC1 CFAP47 SPAG17	4.19e-05	193	214	7	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMEM67 ABCA13 SPATA18 CPLANE1 DNAH5 CFAP47 SPAG17	4.19e-05	193	214	7	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 SPATA18 CCDC81 DNAH5 NPHP1 DNAAF4 SPAG17	4.19e-05	193	214	7	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	USP9X CPLANE1 DYNC1H1 DIP2B WDFY3 STAG2 VPS13B	4.19e-05	193	214	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	10x3'2.3-week_12-13-Hematopoietic-erythroid-mid_erythroid\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	RELN MRC2 FECH PIM2 PRR5 SLC7A5 STOM	4.19e-05	193	214	7	1e19f80c52833fb21a8d597a3ba2c4ff464c4559
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK4 CDH23 PDLIM3 BICC1 FAT3 ARHGAP6 PIEZO2	4.19e-05	193	214	7	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 ABCA13 SPATA18 DNAH5 NPHP1 DNAAF4 SPAG17	4.33e-05	194	214	7	3cd90d01ed5a5ce65aad8284dab2537ec16e3d7c
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMEM67 SPATA18 DNAH5 NPHP1 CFAP47 DNAAF4 SPAG17	4.33e-05	194	214	7	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK4 MRC2 BICC1 FAT3 SLC1A3 ARHGAP6 PIEZO2	4.33e-05	194	214	7	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PGR PTPRD BICC1 SYT6 SLC1A3 PIEZO2 SEMA3E	4.33e-05	194	214	7	71d3c7448b1734de54187f902f65649f9283bd4c
ToppCell	IIH-mono3-\|IIH / Condition, Cell_class and T cell subcluster	DOCK4 EPB41L3 ACSL1 MRC2 SLC1A3 ARHGAP6 SLC7A5	4.47e-05	195	214	7	28a858b04a7b413916c07a8d880f5ea02e985461
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ABCA13 ACSL1 STXBP2 PTPRD NOS1 FAT3 WDFY3	4.47e-05	195	214	7	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	NS-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ABCA13 SPATA18 DNAH5 NPHP1 DNAAF4 GSTA2 SPAG17	4.47e-05	195	214	7	34e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell	IIH-mono3\|IIH / Condition, Cell_class and T cell subcluster	DOCK4 EPB41L3 ACSL1 MRC2 SLC1A3 ARHGAP6 SLC7A5	4.47e-05	195	214	7	c6dd5af582d257be64b718e30f60220c1bf1738a
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 ABCA13 SPATA18 DNAH5 NPHP1 DNAAF4 SPAG17	4.47e-05	195	214	7	6365e3893e38231090ec2dbef010dec71dea3d07
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ABCA13 ACSL1 STXBP2 PTPRD NOS1 FAT3 WDFY3	4.47e-05	195	214	7	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 ABCA13 SPATA18 CPLANE1 DNAH5 NPHP1 SPAG17	4.47e-05	195	214	7	79dc031258579ea328181dda33710dd897f1064a
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 ABCA13 SPATA18 DNAH5 NPHP1 DNAAF4 SPAG17	4.47e-05	195	214	7	db4270c135c392ed443670981656e3cd5b95939d
ToppCell	Control-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	DOCK4 INSR CDH23 EPB41L3 ACSL1 CHST15 NOTCH2	4.47e-05	195	214	7	b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PDE3A PDLIM3 MRC2 BICC1 FAT3 ARHGAP6 PIEZO2	4.62e-05	196	214	7	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	NS-control-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMEM67 SPATA18 CCDC81 DNAH5 NPHP1 DNAAF4 SPAG17	4.62e-05	196	214	7	d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMEM67 SPATA18 DNAH5 NPHP1 CFAP47 DNAAF4 SPAG17	4.77e-05	197	214	7	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMEM67 SPATA18 DNAH5 NPHP1 CFAP47 DNAAF4 SPAG17	4.77e-05	197	214	7	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CCDC81 FBXO24 DNAH5 CRISPLD1 NPHP1 CFAP47 SPAG17	4.77e-05	197	214	7	6e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated-diff\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ABCA13 SPATA18 DNAH5 NPHP1 DNAAF4 GSTA2 SPAG17	4.77e-05	197	214	7	32484fb5dde0a4525dd8028dde01ca5a4e51e4b6
ToppCell	control-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TMEM67 SPATA18 CCDC81 DNAH5 NPHP1 DNAAF4 SPAG17	4.77e-05	197	214	7	e453d085182364ca347cbcc9dc995c62c3353016
ToppCell	control-Epithelial-Ciliated\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TMEM67 SPATA18 CCDC81 DNAH5 NPHP1 DNAAF4 SPAG17	4.77e-05	197	214	7	d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDE3A PDLIM3 MRC2 BICC1 FAT3 ARHGAP6 PIEZO2	4.93e-05	198	214	7	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK4 KANSL1L PTPRD NR3C2 MAP4K3 WDFY3 VPS13B	4.93e-05	198	214	7	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	USP25 FOCAD NR3C2 DIP2B MAP4K3 WDFY3 VPS13B	5.09e-05	199	214	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	PDE3A PDLIM3 MRC2 BICC1 FAT3 ARHGAP6 PIEZO2	5.09e-05	199	214	7	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	10x5'v1-week_14-16-Hematopoietic-erythroid-mid_erythroid\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MRC2 FECH PIM2 PRR5 KIAA1586 SLC7A5 STOM	5.09e-05	199	214	7	e6853b2c0ef6549d5554754c5d5f65825b66025b
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 SPATA18 DNAH5 NPHP1 CFAP47 DNAAF4 SPAG17	5.25e-05	200	214	7	cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell	Biopsy_Control_(H.)-Epithelial-Differentiating_Ciliated\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	ABCA13 SPATA18 DNAH5 NPHP1 CFAP47 SPAG17 PLCE1	5.25e-05	200	214	7	a552a99f5e4fa00dfb7775e5a3e1f62f1530d104
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 SPATA18 DNAH5 NPHP1 CFAP47 DNAAF4 SPAG17	5.25e-05	200	214	7	873def69bf55ccbfc944bc10c5afc06be019c312
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM67 SPATA18 DNAH5 NPHP1 CFAP47 DNAAF4 SPAG17	5.25e-05	200	214	7	79e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Mesoderm\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	RAPGEF3 NAF1 FECH ATP5MGL SLC35G2 SLC7A4	5.73e-05	139	214	6	d441c29852c28928ecb696b4b95e31b30c17116b
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SPATA18 RBM19 CFAP47 BTBD7 ULBP1 IL2RB	6.71e-05	143	214	6	cc396b81a5e47d78c2d1cb49d682391376b63476
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3\|E16.5-samps / Age Group, Lineage, Cell class and subclass	DOCK4 MRC2 BICC1 NOTCH2 YTHDC2 LRRN3	8.42e-05	149	214	6	651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDH23 FAM217A WARS2 NUP210 PRR5 IL2RB	8.73e-05	150	214	6	973252f4de9a1194aea9f3cb0e1f113643f16c91
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8\|TCGA-Thymus / Sample_Type by Project: Shred V9	MRC2 CRISPLD1 BICC1 PIEZO2 SEMA3E PLCE1	9.06e-05	151	214	6	5906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NPHP1 CFAP47 RTTN DIXDC1 SPAG17 PLCE1	1.12e-04	157	214	6	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MASP1 RELN CHST15 NOS1 RLN1 LATS2	1.24e-04	160	214	6	dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MASP1 RELN CHST15 A4GALT RLN1 LATS2	1.29e-04	161	214	6	bf70be1de418615b5442ec684552551edaf1f072
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP7A EPB41L3 FBXO24 TPCN2 RTTN SLC1A3	1.38e-04	163	214	6	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WDR64 PATZ1 VPS4A ERICH6 PRR5 KMO	1.38e-04	163	214	6	2d6fd2562d78be9f83fa35d811eb7e27eb8cc5d1
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP7A EPB41L3 FBXO24 TPCN2 RTTN SLC1A3	1.38e-04	163	214	6	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	PND10-Endothelial-Endothelial_lymphatic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN WNK1 FAM217A CCM2L SLC18A1 PLCE1	1.42e-04	164	214	6	f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPATA18 CCDC81 DNAH5 SYT6 GSTA2 SPAG17	1.42e-04	164	214	6	e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN WNK1 FAM217A CCM2L SLC18A1 PLCE1	1.42e-04	164	214	6	4cfc9f92e49f86d3639e018b35b6a60dc62f494a
Drug	(-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; HL60; HT_HG-U133A	ZNF174 SEC24A PEX6 FASTK RBM19 NUP210 OSBPL1A CAMSAP1 PRR5 LRRK1 KMO VPS13B	3.50e-07	198	211	12	3081_DN
Drug	Androgen Antagonists	RELN ERBB3 PGR STXBP1 NR3C2 NOTCH2 SYT6 SLC1A3	4.72e-07	75	211	8	ctd:D000726
Drug	enzacamene	RELN ERBB3 CYP11B1 PGR STXBP1 NR3C2 NOTCH2 SYT6 SLC1A3	3.33e-06	129	211	9	ctd:C038939
Drug	octylmethoxycinnamate	RELN ERBB3 CYP11B1 PGR STXBP1 NR3C2 NOTCH2 SYT6 SLC1A3	6.16e-06	139	211	9	ctd:C118580
Drug	2-Aminobenzenesulfonamide [3306-62-5]; Down 200; 23.2uM; MCF7; HT_HG-U133A	WNK1 WARS2 A4GALT GNAS CAMSAP1 IPO8 YTHDC2 HDAC7 WDFY3 VPS13B	1.29e-05	192	211	10	3400_DN
Drug	butylparaben	RELN ERBB3 CYP11B1 PGR STXBP1 NR3C2 NOTCH2 SYT6 SLC1A3	1.65e-05	157	211	9	ctd:C038091
Drug	Ethosuximide [77-67-8]; Up 200; 28.4uM; PC3; HT_HG-U133A	ZBTB43 MFAP3 PDLIM3 BICC1 NPHP1 IPO8 TEDC2 LRRK1 ARHGAP6 WDFY3	1.76e-05	199	211	10	7308_UP
Disease	Benign neoplasm of bladder	ERBB3 FANCC NOTCH2 STAG2	2.97e-06	15	206	4	C0154017
Disease	Carcinoma in situ of bladder	ERBB3 FANCC NOTCH2 STAG2	2.97e-06	15	206	4	C0154091
Disease	Neoplasm of uncertain or unknown behavior of bladder	ERBB3 FANCC NOTCH2 STAG2	2.97e-06	15	206	4	C0496930
Disease	Carcinoma of bladder	ERBB3 FANCC NOTCH2 STAG2	6.54e-06	18	206	4	C0699885
Disease	Inherited neuropathies	ATP7A SCN9A TWNK SPG11 SLC1A3	8.52e-06	40	206	5	C0598589
Disease	alcohol use disorder (implicated_via_orthology)	ERBB3 RYR1 STXBP1 STXBP2 NOTCH2 MAP4K3 RIOX1 MAP4K5 ATP1A3	1.01e-05	195	206	9	DOID:1574 (implicated_via_orthology)
Disease	benign neoplasm (implicated_via_orthology)	LATS2 LRRC1 SCRIB	1.83e-05	8	206	3	DOID:0060072 (implicated_via_orthology)
Disease	Hyperpotassemia and Hypertension, Familial	WNK1 NR3C2 GNAS	3.88e-05	10	206	3	C2713447
Disease	Pseudohypoaldosteronism, Type I, Autosomal Recessive	WNK1 NR3C2 GNAS	3.88e-05	10	206	3	C1449843
Disease	Pseudohypoaldosteronism, Type II	WNK1 NR3C2 GNAS	3.88e-05	10	206	3	C1449844
Disease	Pseudohypoaldosteronism, Type I, Autosomal Dominant	WNK1 NR3C2 GNAS	3.88e-05	10	206	3	C1449842
Disease	Pseudohypoaldosteronism, Type I	WNK1 NR3C2 GNAS	3.88e-05	10	206	3	C0268436
Disease	Pseudohypoaldosteronism	WNK1 NR3C2 GNAS	3.88e-05	10	206	3	C0033805
Disease	migraine disorder	DOCK4 FAM47A STXBP2 PTPRD MRC2 FECH BICC1 ZBTB4 CCM2L TMEM68 PLCE1	4.63e-05	357	206	11	MONDO_0005277
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	4.85e-05	2	206	2	DOID:0110471 (implicated_via_orthology)
Disease	gastric adenocarcinoma (is_implicated_in)	ABCA13 XPO1 PLCE1	5.31e-05	11	206	3	DOID:3717 (is_implicated_in)
Disease	kidney cancer (implicated_via_orthology)	LATS2 LRRC1 SCRIB	5.31e-05	11	206	3	DOID:263 (implicated_via_orthology)
Disease	Ciliopathies	TMEM67 CDH23 CPLANE1 DNAH5 DNAH8 NPHP1	1.26e-04	110	206	6	C4277690
Disease	visceral heterotaxy (implicated_via_orthology)	TMEM67 OSBPL1A DNAH5 BICC1	1.27e-04	37	206	4	DOID:0050545 (implicated_via_orthology)
Disease	erythropoietic protoporphyria (is_implicated_in)	CLPX FECH	1.45e-04	3	206	2	DOID:13270 (is_implicated_in)
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	TDRD15 PDE3A INSR HCAR1 SPG11 APOB SLC18A1 MAP4K5	1.77e-04	222	206	8	EFO_0008317, EFO_0020943
Disease	Alternating hemiplegia of childhood	SLC1A3 ATP1A3	2.88e-04	4	206	2	C0338488
Disease	Hereditary sensory and autonomic neuropathy type 2	WNK1 SCN9A	2.88e-04	4	206	2	cv:C5574675
Disease	Episodic Ataxia	UBR4 SLC1A3	2.88e-04	4	206	2	C1720189
Disease	Neuropathy, Hereditary Sensory And Autonomic, Type IIA	WNK1 SCN9A	2.88e-04	4	206	2	C2752089
Disease	Neuropathy, hereditary sensory and autonomic, type 2A	WNK1 SCN9A	2.88e-04	4	206	2	cv:C2752089
Disease	NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIA	WNK1 SCN9A	2.88e-04	4	206	2	201300
Disease	Endogenous depression	RELN GNAS NOS1 DIXDC1	2.99e-04	46	206	4	C0011573
Disease	Familial aplasia of the vermis	TMEM67 CPLANE1 NPHP1	3.50e-04	20	206	3	cv:C0431399
Disease	Colorectal Carcinoma	ABCA13 WNK1 PTPRD NR3C2 GNAS DNAH8 WRN APOB TLR9 ITPRID1 ABCG1 EIF4G1 TNS4 SPAG17	4.49e-04	702	206	14	C0009402
Disease	cardiovascular disease biomarker measurement, ankle brachial index	DNAH5 FAT3	4.78e-04	5	206	2	EFO_0003912, EFO_0005278
Disease	Congenital cataract	PRX TDRD7	7.14e-04	6	206	2	C0009691
Disease	nephronophthisis (is_implicated_in)	TMEM67 NPHP1	7.14e-04	6	206	2	DOID:12712 (is_implicated_in)
Disease	epilepsy (implicated_via_orthology)	ITGA7 SCN9A NOS1 DYNC1H1 SLC1A3 ATP1A3	1.03e-03	163	206	6	DOID:1826 (implicated_via_orthology)
Disease	carcinoma (implicated_via_orthology)	ERBB3 LATS2 LRRC1 SCRIB	1.06e-03	64	206	4	DOID:305 (implicated_via_orthology)
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	TDRD15 PDE3A HCAR1 SPG11 APOB SLC18A1 MAP4K5	1.07e-03	225	206	7	EFO_0008317, EFO_0020947
Disease	glutamate measurement	CDH23 SLC1A3 OTOG	1.07e-03	29	206	3	EFO_0010487
Disease	Familial aplasia of the vermis	TMEM67 POC1B CPLANE1	1.18e-03	30	206	3	C0431399
Disease	serum alanine aminotransferase measurement	ERBB3 CYP11B1 INSR SPATA18 PEX6 NUP210 DIP2B TPCN2 APOB XPO1 ATP10D MAP4K5 PCDHGB4 SEMA3E PLCE1	1.23e-03	869	206	15	EFO_0004735
Disease	Idiopathic Myoclonic Epilepsy	STXBP1 SCN9A	1.32e-03	8	206	2	C0338478
Disease	Symptomatic Myoclonic Epilepsy	STXBP1 SCN9A	1.32e-03	8	206	2	C0338479
Disease	Benign Infantile Myoclonic Epilepsy	STXBP1 SCN9A	1.32e-03	8	206	2	C0751120
Disease	Myoclonic Encephalopathy	STXBP1 SCN9A	1.32e-03	8	206	2	C0438414
Disease	Myoclonic Absence Epilepsy	STXBP1 SCN9A	1.32e-03	8	206	2	C0393703
Disease	Early Childhood Epilepsy, Myoclonic	STXBP1 SCN9A	1.32e-03	8	206	2	C0393695
Disease	esterified cholesterol measurement, intermediate density lipoprotein measurement	TDRD15 APOB	1.32e-03	8	206	2	EFO_0008589, EFO_0008595
Disease	pseudohypoaldosteronism (is_implicated_in)	WNK1 NR3C2	1.32e-03	8	206	2	DOID:4479 (is_implicated_in)
Disease	schizophrenia (implicated_via_orthology)	RELN NOS1 KMO LRRN3	1.33e-03	68	206	4	DOID:5419 (implicated_via_orthology)
Disease	susceptibility to mononucleosis measurement	FAM47A PTPRD DNAH8 HDAC7	1.40e-03	69	206	4	EFO_0008403
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	TDRD15 SPG11 APOB SLC18A1 MAP4K5	1.63e-03	121	206	5	EFO_0008595, EFO_0020943
Disease	calcium measurement	CPA4 PDE3A ABCG4 C19orf12 A4GALT SHOC1 GNAS NOS1 MAP4K3 MAP4K5 ATP1A3 PLCE1	1.63e-03	628	206	12	EFO_0004838
Disease	Nephronophthisis	TMEM67 NPHP1	1.69e-03	9	206	2	cv:C0687120
Disease	Myoclonic Epilepsy	STXBP1 SCN9A	1.69e-03	9	206	2	C0014550
Disease	Bipolar Disorder	RELN ERBB3 ABCA13 PIK3C3 DNAH8 SLC1A3 SLC18A1 DIXDC1 ATP1A3 IL2RB	2.03e-03	477	206	10	C0005586
Disease	Epilepsy, Myoclonic, Infantile	STXBP1 SCN9A	2.10e-03	10	206	2	C0917800
Disease	level of Triacylglycerol (51:3) in blood serum	APOB MAP4K5	2.10e-03	10	206	2	OBA_2045163
Disease	adult onset asthma, body mass index	ERBB3 SPATA18	2.10e-03	10	206	2	EFO_0004340, EFO_1002011
Disease	cystic kidney disease (implicated_via_orthology)	TMEM67 BICC1	2.10e-03	10	206	2	DOID:2975 (implicated_via_orthology)
Disease	Astigmatism	DOCK4 ABCA13 HERC2 DNAH5 BICC1	2.16e-03	129	206	5	HP_0000483
Disease	tongue squamous cell carcinoma (is_marker_for)	ERBB3 FANCC SLC7A5	2.19e-03	37	206	3	DOID:0050865 (is_marker_for)
Disease	Nonsyndromic Deafness	CDH23 OSBPL2 STRC OTOG	2.52e-03	81	206	4	C3711374
Disease	endometrial carcinoma, endometriosis	PGR PTPRD	2.56e-03	11	206	2	EFO_0001065, EFO_1001512
Disease	eye measurement, sun exposure measurement	DIPK2A HDAC7	2.56e-03	11	206	2	EFO_0004731, EFO_0010729
Disease	level of Diacylglycerol (18:1_18:1) in blood serum	APOB MAP4K5	2.56e-03	11	206	2	OBA_2045170
Disease	Myoclonic Astatic Epilepsy	STXBP1 SCN9A	2.56e-03	11	206	2	C0393702
Disease	pigmentation disease (is_implicated_in)	HERC2 TPCN2	2.56e-03	11	206	2	DOID:10123 (is_implicated_in)
Disease	functional brain measurement	STXBP2 POC1B C3P1 PLCE1	2.64e-03	82	206	4	EFO_0007849
Disease	ciliopathy (implicated_via_orthology)	TMEM67 MAP4K3 MAP4K5	2.74e-03	40	206	3	DOID:0060340 (implicated_via_orthology)
Disease	comparative body size at age 10, self-reported	RELN WNK1 FOCAD MFAP3 STXBP1 PIK3C3 GNAS GCN1 BTBD7	2.91e-03	420	206	9	EFO_0009819
Disease	Depression, Neurotic	RELN NOS1 DIXDC1	2.94e-03	41	206	3	C0282126
Disease	Melancholia	RELN NOS1 DIXDC1	2.94e-03	41	206	3	C0025193
Disease	obsolete_red blood cell distribution width	PATZ1 INSR PSMB5 HCAR1 CDH23 WNK1 NUP210 A4GALT FECH C1orf105 SEC23B DIP2B TUT7 APOB SLC35G2 GSTA2 MAP4K5 SLC7A5 IL2RB	2.96e-03	1347	206	19	EFO_0005192
Disease	Autism Spectrum Disorders	RELN NSUN2 DIPK2A LRRN3	3.01e-03	85	206	4	C1510586
Disease	Renal dysplasia and retinal aplasia (disorder)	POC1B NPHP1	3.06e-03	12	206	2	C0403553
Disease	Congenital muscular dystrophy	ITGA7 RYR1	3.06e-03	12	206	2	cv:C0699743
Disease	Depressive Syndrome	RELN NOS1 DIXDC1	3.15e-03	42	206	3	C0086133
Disease	triglycerides in large LDL measurement	TDRD15 APOB MAP4K5	3.37e-03	43	206	3	EFO_0022319
Disease	Infantile Severe Myoclonic Epilepsy	STXBP1 SCN9A	3.60e-03	13	206	2	C0751122
Disease	illegal drug consumption	WDR64 SYT6	3.60e-03	13	206	2	EFO_0005431
Disease	developmental and epileptic encephalopathy (implicated_via_orthology)	STXBP1 STXBP2	3.60e-03	13	206	2	DOID:0112202 (implicated_via_orthology)
Disease	Hereditary Motor and Sensory-Neuropathy Type II	WNK1 SCN9A	3.60e-03	13	206	2	C0270914
Disease	Nephronophthisis	TMEM67 NPHP1	3.60e-03	13	206	2	C0687120
Disease	Bardet-Biedl Syndrome	TMEM67 NPHP1	3.60e-03	13	206	2	C0752166
Disease	Malignant Head and Neck Neoplasm	ERBB3 FANCC FANCE	3.60e-03	44	206	3	C0278996
Disease	concentration of large LDL particles measurement	TDRD15 IGSF23 APOB	3.60e-03	44	206	3	EFO_0022160
Disease	cholesterol in medium VLDL measurement	TDRD15 IGSF23 APOB	3.60e-03	44	206	3	EFO_0022225
Disease	cholesterol to total lipids in large VLDL percentage	TDRD15 APOB MAP4K5	3.83e-03	45	206	3	EFO_0022236
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	TDRD15 SPG11 APOB SLC18A1 MAP4K5	4.13e-03	150	206	5	EFO_0004611, EFO_0020947
Disease	Bardet-Biedl syndrome (is_implicated_in)	TMEM67 NPHP1	4.18e-03	14	206	2	DOID:1935 (is_implicated_in)
Disease	asthma, body mass index	ERBB3 PIK3C3	4.18e-03	14	206	2	EFO_0004340, MONDO_0004979
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	TDRD15 APOB	4.18e-03	14	206	2	EFO_0004611, EFO_0008589
Disease	Fanconi anemia	FANCC FANCE	4.18e-03	14	206	2	cv:C0015625
Disease	tuberculosis	FAM47A C5orf22 PTPRD XPO1 IL2RB VPS13B	4.22e-03	216	206	6	MONDO_0018076
Disease	Depressive disorder	RELN NR3C2 NOS1 BICC1 SLC18A1 DIXDC1 ATP1A3	4.34e-03	289	206	7	C0011581
Disease	total lipids in lipoprotein particles measurement	TDRD15 APOB MAP4K5	4.60e-03	48	206	3	EFO_0022309
Disease	low density lipoprotein triglyceride measurement	TDRD15 APOB	4.80e-03	15	206	2	EFO_0009946
Disease	response to statin, LDL cholesterol change measurement	TDRD15 APOB	4.80e-03	15	206	2	EFO_0007804, GO_0036273
Disease	liver volume	GSTA2 MAP4K5	4.80e-03	15	206	2	EFO_0600048
Disease	triacylglycerol 52:3 measurement	APOB MAP4K5	4.80e-03	15	206	2	EFO_0010415
Disease	Gastro-enteropancreatic neuroendocrine tumor	NOTCH2 IL2RB	4.80e-03	15	206	2	C2930967

Protein segments in the cluster

Peptide	Gene	Start	Entry
PQEDLEALVMPTLRQ	PPP2R1A	236	P30153
LQVPKFVDLTPMVRD	C2orf16	201	Q68DN1
PMPAIVLQILEENIR	EXOC3L1	421	Q86VI1
QEDMPTNPAILAVLD	ERICH6	471	Q7L0X2
MNEFSTLPLPNLRVV	ERBB3	91	P21860
IALELVNNPPVMFFD	ABCG4	211	Q9H172
QILMELPPAEQQRLF	C19orf12	86	Q9NSK7
LLLEPMFEVPNSDIV	CLPX	571	O76031
AIALELVNNPPVMFF	ABCG1	226	P45844
FPNVQMLPLDLRELF	A4GALT	136	Q9NPC4
LMDDLKVLQPTVFPV	ACSL1	351	P33121
LTPFMVNIPKRLEEV	DIXDC1	611	Q155Q3
ILRPIEMSDEIPNQF	ABCA13	1526	Q86UQ4
REDLFQIPMVPLIPA	SLC7A4	536	O43246
LGPLEIQQFAMLLRE	CCM2L	426	Q9NUG4
LLYEQLLEPPTMEVL	BIK	16	Q13323
VLMFELPIAGILQPV	BICC1	206	Q9H694
APLVLKPNVMVFIAE	CAMSAP1	311	Q5T5Y3
ITDVQDMDPIFINLP	CDH23	226	Q9H251
MPFLELDTNLPANRV	DDTL	1	A6NHG4
MAPFVRNLVEKTPAL	ATP5MGL	1	Q7Z4Y8
QITPRLFMPLDETIQ	ATP10D	561	Q9P241
VIQPPMIAEFIRELG	ATP7A	536	Q04656
EEPDLALLQPLVMAA	C17orf113	421	A0A1B0GUU1
MEFLAPLKPVAIRIV	RBM19	311	Q9Y4C8
RIDMALQTALPPALF	NFILZ	181	A0A5F9ZHS7
LLPVINTMLQLSPEE	RGPD5	1731	Q99666
LLPVINTMLQLSPEE	RGPD8	1731	O14715
LDPLMPELLVFPAQT	NSUN5	181	Q96P11
NAPEVIFQSLPNLIM	PCDHGB4	341	Q9UN71
QEAVSMIPPLLLNVR	NSUN2	161	Q08J23
FLIIFPPVIMGLQLD	OR6C65	151	A6NJZ3
PLSLVEQVIPIIDLM	ANKRD13A	371	Q8IZ07
LASIEPELPMQLVSQ	NUP210	816	Q8TEM1
NLGEDMPPDLLLQVL	FAM47C	136	Q5HY64
PLEQQFMPCLERILA	FASTK	291	Q14296
VLMPPEQLLQDARSF	NOTCH2	1551	Q04721
GITAIELAELQPPMF	MAP4K3	201	Q8IVH8
LDENDNAPALLMPRV	PCDHA3	556	Q9Y5H8
DIDNIVIPMSLVAPA	KANSL1L	771	A0AUZ9
FPAMLVEIISDQLPK	NR3C2	956	P08235
QILPGTEAEMENLPL	ITPRID1	686	Q6ZRS4
VILFEMLVGQPPFLA	LATS2	901	Q9NRM7
LPVPLQELVPELFMT	LRRK1	1211	Q38SD2
DVDLIPPFNRMLLEV	HERC2	1716	O95714
IAFAMQALEPPLDIA	SPATA18	426	Q8TC71
DLGEMILLLPFSQPE	GSTA2	101	P09210
APAPVMLFVALKELV	KIAA1586	341	Q9HCI6
FPMSVLNNTIAEPLI	OR51F2	11	Q8NH61
ILAPEPLVMDNLDSI	PDE3A	671	Q14432
MALAVLRVLEPFPTE	PEX6	1	Q13608
PFTENLNLISMLVDP	DNAH8	3421	Q96JB1
LNLISMLVDPPTIGE	DNAH8	3426	Q96JB1
MPFLELDTNLPANRV	DDT	1	P30046
SVLIPPMELENNLFL	DIP2B	1221	Q9P265
EMINPYRNLPLAIII	SLC7A5	266	Q01650
SALPENPAALVVVLM	MRC2	1406	Q9UBG0
MAERPEDLNLPNAVI	POLE3	1	Q9NRF9
PSLALIMPIVQRAFQ	GCN1	1611	Q92616
NPKMRPTFLEIVNLL	INSR	1276	P06213
QALDMPVLPVTATEI	TWNK	46	Q96RR1
VIDLQISTPPVMDIL	POC1B	351	Q8TC44
PLINVLMANVLLLVP	OR51A2	271	Q8NGJ7
PLINVLMANVLLLVP	OR51A4	271	Q8NGJ6
FIALREMANLPVPSL	OXA1L	231	Q15070
MPVIFNEPLSFLQRL	OSBPL1A	566	Q9BXW6
GMVADPDNPLVLDIL	DDOST	201	P39656
FLAILPPIILMTQVD	OR6C4	151	Q8NGE1
LVIFPPLAMGLQLDF	OR6C76	151	A6NM76
IQRLPPEIANFMQLV	LRRC1	71	Q9BTT6
LGLDPDQLFMLQPRE	NDOR1	266	Q9UHB4
LPPLILNCRAFVEEM	MFAP3	241	P55082
FMSFLEPQIISIDLP	RELN	1551	P78509
FAAVRDLMANLTLPP	MED14	1436	O60244
ALIERLEDAPPVNQM	NOS1	1051	P29475
VQILVPPARADIMLF	PATZ1	161	Q9HBE1
LFMVPPDLQNEVLIS	ARHGAP6	601	O43182
PLINLLMSIEPDVIY	PGR	686	P06401
MSLQAPPRLLELAEQ	PRAMEF12	1	O95522
PVLTQAMEALQDRPV	COG6	246	Q9Y2V7
ANLDFLNIPLTIPEM	APOB	3121	P04114
FLANMTSVILPEDLP	CDHR2	26	Q9BYE9
DFPANLVLQLMPLKT	IGSF23	36	A1L1A6
KLLVQDFFLLPAQPM	KMO	271	O15229
LEVTLIPQPDLRNVM	DOCK4	1071	Q8N1I0
TNISVNLMPELAPIE	B4GALT6	366	Q9UBX8
LVPRQEFLNMVPDTE	C3P1	146	Q6ZMU1
LNLPLRMTPAQIFQE	CPLANE1	1056	Q9H799
PVTDMAPLNKLLVDV	DNAH17	2746	Q9UFH2
EIPIVPLNFVMISLE	CCDC81	101	Q6ZN84
IPAMVVPNATLLEKL	CRISPLD1	21	Q9H336
ERMQLLLTLAFNPEP	DIPK2A	201	Q8NDZ4
LDLIRNMFPPNLVEA	SLC1A3	171	P43003
ILEKMDIFLLPVANP	CPA4	211	Q9UI42
DLLIPVNMPADTVFD	C5orf22	56	Q49AR2
IQVLDMNDLRPLFSP	FAT3	146	Q8TDW7
PSLAMVLLQDPQDIP	FANCC	346	Q00597
PFENLRLMAPISLQV	IL2RB	126	P14784
LMALREPAAQAPVKL	IGHD	261	P01880
FPLLMTLFELARNPN	CYP11B1	321	P15538
IVAAMSNLVPPVELA	GNAS	106	P63092
VRTQPVLNDLMPDIA	BTBD7	861	Q9P203
PVALLMLLVDADQPE	BCAS4	26	Q8TDM0
LVVTLEQPPNLLRMF	EIF4G1	1531	Q04637
AFDPLDQQMPLALSL	FBXO24	341	O75426
ASIVLDELQPQAPMA	MAN2B2	451	Q9Y2E5
VELLESPVLNAFVMP	MASP1	556	P48740
EITPFLLFIMANIPL	ATP1A3	776	P13637
LELLMPPVTDNANAR	DNAAF4	351	Q8WXU2
ERLSLPPNVRIMFEV	DYNC1H1	2331	Q14204
NLGEDMPPDLLLQVL	FAM47A	136	Q5JRC9
QVMPPLLIVAFVLGA	HCAR1	16	Q9BXC0
FIELPLSIAGMAIPQ	ITGA7	846	Q13683
PDAQVLMLGQILELP	FANCE	431	Q9HB96
NILSPLMLPNLEIPF	FAM186A	31	A6NE01
LMLPNLEIPFSVKDI	FAM186A	36	A6NE01
RDLMTLPIQNKLAPF	FECH	96	P22830
VVMPIAREFSPDLVL	HDAC7	781	Q8WUI4
LEIPVEQLMLEPNLS	FAM217A	56	Q8IXS0
IPSQMLLENFSAAIP	SLC22A11	31	Q9NSA0
RLAAAMPVAFLEPQL	RYR1	3196	P21817
PVPLDITTVMDINIL	CFAP47	1316	Q6ZTR5
TIVIPFKNPTMEDVL	CFAP47	2761	Q6ZTR5
INQALSMPEVSIAPL	NOC4L	456	Q9BVI4
VRTELMEQIPPIAIF	PPP4R1L	101	Q9P1A2
MEQIPPIAIFLQENR	PPP4R1L	106	Q9P1A2
LAARQEDAPMIEPLV	EPB41L3	766	Q9Y2J2
ALQFPKIMEFLPVLL	HELB	211	Q8NG08
ADSSQVPNLIPVLMF	FOCAD	481	Q5VW36
LAIPNIVMAPALEDV	DNAH5	1016	Q8TE73
LQPELMPSQLAFRDL	NPHP1	351	O15259
ITAIELGELQPPMFD	MAP4K5	206	Q9Y4K4
PALEFVQMIKLSDLP	MTBP	301	Q96DY7
TNAPELQVPLFIMFT	OR5B17	16	Q8NGF7
LLYRDINIPLLPMEQ	PTPRD	956	P23468
APQDSMLVLLPQLAE	OTOG	1986	Q6ZRI0
EEREPLIIAMQIFLP	IPO8	166	O15397
VSVLLPMPIQEERFV	TMEM67	596	Q5HYA8
FPPLQILAENLTMVT	OR10R2	16	Q8NGX6
LVLLEMPFSPQLESE	MUC3B	1001	Q9H195
QLMRLFVVVPDAPLQ	SMG8	906	Q8ND04
FVVVPDAPLQIILMP	SMG8	911	Q8ND04
GPLQEMEELPTDLLQ	RTL1	61	A6NKG5
AFILQNLLVIPMPTE	RTTN	1436	Q86VV8
IPPENMDQVSLLISV	SYT6	436	Q5T7P8
VPQDPAVLRQSILDM	WARS2	81	Q9UGM6
LPIIEMVPQFLENLT	USP9X	276	Q93008
VQAILPLQMFLFEVP	TDRD15	156	B5MCY1
PLQMFLFEVPKIISQ	TDRD15	161	B5MCY1
VLMAELLPLVSAAQP	TEDC2	386	Q7L2K0
ALPNLEILMIGENPI	LRRN3	186	Q9H3W5
QPLIQFPEEVASILM	PLCE1	526	Q9P212
IMLEFIANLPPELKA	RLN1	86	P04808
ARVPPAIVQMLLVLQ	PRR5	171	P85299
VFIPMPENLLVNLNE	SEC24A	576	O95486
STMFILQEPIIPLDG	SLC35G2	301	Q8TBE7
LVPSIMSNLLNPDAI	NT5DC3	71	Q86UY8
GFMLVLERPLPAQDL	PIM2	111	Q9P1W9
ILTSFELVKVPDPQM	PIK3C3	246	Q8NEB9
MLISEEQPAQPALPI	PIP4P2	131	Q8N4L2
ALMLPNGQLLPEVII	SCN9A	636	Q15858
LLDFPCINPLVAQLM	SHOC1	1046	Q5VXU9
VNPDMVPFVLPNVLL	SCYL2	381	Q6P3W7
VAAKLAPNIPLEMEL	PDLIM3	166	Q53GG5
MDVPPAILATNKILV	WRN	1171	Q14191
IQRLPPEVANFMQLV	SCRIB	71	Q14160
RFLQEMIAIPPQAIK	TDRD7	756	Q8NHU6
DLIPPFNRMLLEVTF	HERC2P3	446	Q9BVR0
PMRAIVPILLDANVS	STXBP1	386	P61764
RIPFDLMDTVPAEQL	ARHGAP35	401	Q9NRY4
ITMPIAFNEPLSFLQ	OSBPL2	91	Q9H1P3
IAILNTSVAPMLNPF	OR6C3	271	Q9NZP0
ELSEPQLRAMLPVLQ	STRC	1011	Q7RTU9
MEEVPLALTAQVPGL	AARS2	696	Q5JTZ9
FLEAILPLAVQAAME	RIOX1	431	Q9H6W3
LDDAQEILQARFPMP	SEC23B	691	Q15437
TIVFPLPIDMLQGII	STOM	266	P27105
PQLLAIMAELGIPIT	SPAG17	231	Q6Q759
VLTPEIMAPILANAD	ADRM1	291	Q16186
NMNLPILFQVPDVLS	C1orf105	51	O95561
FQPNARLIVMLRDPV	CHST15	381	Q7LFX5
VLPDVMNPRVFENIL	ZBTB43	71	O43298
FTLPLPAQAVDMIID	SPG11	191	Q96JI7
LPDVVPEGTLLNMVL	RAPGEF3	31	O95398
MVAENFVPPLLDAVL	XPO1	771	O14980
AVQLSPAIPVFAAML	ZDHHC9	61	Q9Y397
LMALFLQQPVSELPE	WDFY3	1776	Q8IZQ1
AQVAIDAKVPIIPMF	TMEM68	221	Q96MH6
LELLVMEQFLTILPP	ZNF174	86	Q15697
MEQFLTILPPEIQAR	ZNF174	91	Q15697
MDFLLEVQAAVPGLP	TLR9	771	Q9NR96
LNNVLLTFPPERVNM	SAGE2P	181	A6NJ88
MIAAPEIPTDFNLLQ	STAG2	1	Q8N3U4
NQMILELDPTFQLLP	TNS4	106	Q8IZW8
FKMPTVTVPQLELDV	PRX	1211	Q9BXM0
LDSDALNRPLNIMIP	TNPO2	161	O14787
MKLIVPVLLDAAVPA	STXBP2	386	Q15833
DMPLSIAPEQVLQTF	TREH	56	O43280
EDQVPGPFLVMVLIQ	PIEZO2	2226	Q9H5I5
FIVPFLPLLLVDEME	USP25	961	Q9UHP3
PANVVMFEQRLLPAV	UAP1L1	191	Q3KQV9
LAALPVALNMVLPDE	ZBTB4	941	Q9P1Z0
IAMFLEPLDLPNKRV	SENP8	71	Q96LD8
PLADMTPQLLLEVSQ	TLNRD1	171	Q9H1K6
DPFPAAIILKVALNM	PBK	136	Q96KB5
LEMLVLEQFLGTLPP	ZNF446	66	Q9NWS9
LEFQTPELLRMPLQE	YTHDC2	761	Q9H6S0
PESLLAPDLMAFTIQ	VPS13B	916	Q7Z7G8
VVAANPEAMLDLEPQ	ZNF236	811	Q9UL36
ELQIFKDPVPIISME	SEMA3E	481	O15041
ELSEPQLRAMLPVLQ	STRCP1	1011	A6NGW2
ENLIPIEPLTLQARM	ULBP1	111	Q9BZM6
FMDLEQAVLPAVIPK	WNK1	1981	Q9H4A3
MALASVLERPLPVNQ	PSMB5	1	P28074
DIQFPAIMSQPDVLL	TUT7	356	Q5VYS8
LPLPIVASNLMIEFA	UBR4	3631	Q5T4S7
DMLLNINVESLTPPV	ZP2	471	Q05996
KMALPELVRAQVPFS	USP5	516	P45974
LVLLTTANNPDVMIP	TPCN2	266	Q8NHX9
LVLMEAAPELVFEPT	TRPV5	96	Q9NQA5
DRNMAIPFPDVELIV	WDR64	616	B1ANS9
FANMGVAILEPTLPI	SLC18A1	311	P54219
IPLPEEAARAQMFRL	VPS4A	291	Q9UN37
LLAPLNVEMDPEIQR	KRT72	106	Q14CN4
LVIIESMTNLPPVNE	NAF1	211	Q96HR8