Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpotassium channel activity

KCNMB2 KCNH8 CCT8L2 KCNJ4 ABCC8 KCNAB1 KCNE2 GRIK5 KCNQ4

4.71e-061281959GO:0005267
GeneOntologyMolecularFunctiongated channel activity

KCNMB2 KCNH8 BEST3 CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 KCNE2 TPCN2 GRIK5 PIEZO2 KCNQ4 TMC5

5.50e-0633419514GO:0022836
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

KCNMB2 KCNH8 CCT8L2 KCNJ4 ABCC8 KCNAB1 KCNE2 GRIK5 SLC9C2 KCNQ4

5.87e-0616719510GO:0015079
GeneOntologyMolecularFunctionactivin receptor activity, type I

ACVR1B ACVR1C TGFBR1

9.04e-0651953GO:0016361
GeneOntologyMolecularFunctionmonoatomic cation channel activity

KCNMB2 KCNH8 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 KCNE2 TPCN2 GRIK5 PIEZO2 KCNQ4

3.44e-0534319513GO:0005261
GeneOntologyMolecularFunctionmonoatomic ion channel activity

KCNMB2 KCNH8 BEST3 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 KCNE2 TPCN2 GRIK5 PIEZO2 KCNQ4 TMC5

4.76e-0545919515GO:0005216
GeneOntologyMolecularFunctionactivin receptor activity

ACVR1B ACVR1C TGFBR1

7.38e-0591953GO:0017002
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 SLC29A4 KCNE2 SLC5A10 TPCN2 GRIK5 SLC9C2 PIEZO2 KCNQ4

9.46e-0566419518GO:0008324
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 BEST3 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 SLC29A4 KCNE2 SLC5A10 TPCN2 GRIK5 SLC9C2 PIEZO2 KCNQ4 TMC5

1.03e-0479319520GO:0015075
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

ACVR1B FGFR2 ACVR1C TGFBR1 MST1R EPHA8

1.85e-04851956GO:0019199
GeneOntologyMolecularFunctionactivin binding

ACVR1B ACVR1C TGFBR1

1.89e-04121953GO:0048185
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

KCNMB2 KCNH8 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 KCNE2 SLC5A10 TPCN2 GRIK5 SLC9C2 KCNQ4

2.01e-0446519514GO:0046873
GeneOntologyMolecularFunctionchannel activity

KCNMB2 KCNH8 BEST3 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 KCNE2 TPCN2 GRIK5 PIEZO2 KCNQ4 TMC5

2.10e-0452519515GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

KCNMB2 KCNH8 BEST3 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 KCNE2 TPCN2 GRIK5 PIEZO2 KCNQ4 TMC5

2.14e-0452619515GO:0022803
GeneOntologyMolecularFunctiontransmembrane transporter activity

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 BEST3 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A SLC25A38 KCNAB1 STRA6 SLC29A4 KCNE2 SLC5A10 TPCN2 IPO8 SLC6A16 GRIK5 SLC9C2 SLC22A12 PIEZO2 KCNQ4 TMC5

2.19e-04118019525GO:0022857
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

TSHR F2RL2 QRFPR KISS1R NPR1 NTSR1 RXFP4

3.36e-041331957GO:0008528
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

KCNH8 KCNJ4 ABCC8 SCN10A KCNAB1 KCNE2 TPCN2 KCNQ4

4.31e-041821958GO:0005244
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 KCNE2 SLC5A10 TPCN2 GRIK5 SLC9C2 KCNQ4

4.55e-0462719516GO:0022890
GeneOntologyMolecularFunctionpeptide receptor activity

TSHR F2RL2 QRFPR KISS1R NPR1 NTSR1 RXFP4

4.58e-041401957GO:0001653
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

KCNMB2 CCT8L2 KCNJ4 ABCC8 KCNE2 TPCN2 GRIK5

4.58e-041401957GO:0099094
GeneOntologyMolecularFunctionvoltage-gated channel activity

KCNH8 KCNJ4 ABCC8 SCN10A KCNAB1 KCNE2 TPCN2 KCNQ4

4.63e-041841958GO:0022832
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

KCNH8 KCNJ4 ABCC8 KCNAB1 KCNE2 KCNQ4

4.97e-041021956GO:0005249
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

KCNMB2 BEST3 CCT8L2 KCNJ4 ABCC8 KCNE2 TPCN2 GRIK5

6.35e-041931958GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

KCNMB2 BEST3 CCT8L2 KCNJ4 ABCC8 KCNE2 TPCN2 GRIK5

7.26e-041971958GO:0022834
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

KCNH8 KCNJ4 ABCC8 KCNAB1 KCNE2 TPCN2 KCNQ4

7.47e-041521957GO:0022843
GeneOntologyMolecularFunctiontransporter activity

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 BEST3 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A SLC25A38 KCNAB1 STRA6 SLC29A4 KCNE2 SLC5A10 TPCN2 IPO8 SLC6A16 GRIK5 SLC9C2 SLC22A12 PIEZO2 KCNQ4 TMC5

8.05e-04128919525GO:0005215
GeneOntologyMolecularFunctiontransmembrane receptor protein serine/threonine kinase activity

ACVR1B ACVR1C TGFBR1

9.25e-04201953GO:0004675
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 BEST3 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 KCNE2 SLC5A10 TPCN2 GRIK5 SLC9C2 KCNQ4

1.27e-0375819517GO:0015318
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

TSPAN12 GPR82 ADGRB2 TSHR ACVR1B F2RL2 QRFPR TAS2R13 KISS1R ABCC8 ADGRF4 FGFR2 IL17RB NPR1 DRD2 GPR35 NTSR1 GRIK5 ACVR1C OR9A1P TGFBR1 MST1R RXFP4 IL6R EPHA8

1.58e-03135319525GO:0004888
GeneOntologyMolecularFunctionMutSalpha complex binding

ATR MUTYH

1.93e-0371952GO:0032407
GeneOntologyMolecularFunctionMutLalpha complex binding

ATR MUTYH

1.93e-0371952GO:0032405
GeneOntologyBiologicalProcessgrowth

TSHR BCL2L1 ACVR1B SESN1 PRDM11 CYFIP1 FDPS ASPM FGFR2 STRA6 MMP13 PLS1 PHIP IL17RB AKAP6 NPR1 DRD2 DERL2 ACVR1C CYFIP2 TGFBR1 MEGF8 LRP1 KDM2A MAEL C9orf72 CDH1 IL6R SOS1

5.96e-06123519629GO:0040007
GeneOntologyBiologicalProcessneurotransmitter transport

SYN3 LRRK2 NAPA BCL2L1 SYNJ1 ABCC8 SLC29A4 DRD2 SLC6A16 GRIK5 CADPS CADPS2

7.36e-0625919612GO:0006836
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 BEST3 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 SLC29A4 AKAP6 KCNE2 DRD2 SLC5A10 TPCN2 SLC6A16 GPR35 NTSR1 GRIK5 SLC9C2 IBTK PIEZO2 KCNQ4 PLCH2 TMC5

7.44e-06111519627GO:0034220
GeneOntologyBiologicalProcesssynaptic vesicle cycle

ATP6V1C1 ATP6V0A1 SYN3 LRRK2 NAPA BCL2L1 CYFIP1 SYNJ1 GRIK5 CADPS C9orf72 CADPS2

8.93e-0626419612GO:0099504
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 SLC29A4 AKAP6 KCNE2 DRD2 SLC5A10 TPCN2 SLC6A16 GPR35 NTSR1 SLC9C2 IBTK PIEZO2 KCNQ4 PLCH2

1.09e-0594219624GO:0098655
GeneOntologyBiologicalProcessvesicle-mediated transport in synapse

ATP6V1C1 ATP6V0A1 SYN3 LRRK2 NAPA BCL2L1 CYFIP1 SYNJ1 GRIK5 CADPS LRP1 C9orf72 CADPS2

1.30e-0532119613GO:0099003
GeneOntologyBiologicalProcessexport from cell

SYN3 LRRK2 NAPA BCL2L1 F2RL2 SNX19 KISS1R SYNJ1 ABCC8 MMP13 SLC29A4 SEL1L KCNE2 EXOC6 DRD2 TPCN2 NTSR1 PORCN GRIK5 ACVR1C RFX3 TXLNA CADPS LRP1 C9orf72 CADPS2

3.78e-05115319626GO:0140352
GeneOntologyBiologicalProcessmonoatomic ion transport

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 BEST3 PKDREJ KLHL3 CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 SLC29A4 AKAP6 KCNE2 DRD2 SLC5A10 TPCN2 SLC6A16 GPR35 NTSR1 GRIK5 SLC9C2 SLC22A12 IBTK PIEZO2 KCNQ4 PLCH2 TMC5

4.33e-05137419629GO:0006811
GeneOntologyBiologicalProcessregulation of growth

TSHR BCL2L1 ACVR1B SESN1 PRDM11 CYFIP1 FDPS FGFR2 PLS1 PHIP IL17RB AKAP6 NPR1 DRD2 DERL2 TGFBR1 MEGF8 LRP1 MAEL CDH1

5.39e-0577719620GO:0040008
GeneOntologyBiologicalProcesspotassium ion transport

KCNMB2 KCNH8 CCT8L2 KCNJ4 ABCC8 KCNAB1 AKAP6 KCNE2 DRD2 SLC9C2 KCNQ4

6.16e-0527219611GO:0006813
GeneOntologyBiologicalProcesscell morphogenesis

HGF NCKAP1 MYO7A LRRK2 BRWD3 CYFIP1 SSH1 NBEAL2 FGFR2 PLS1 PHIP CNTN4 DRD2 CNTNAP1 FRYL ARTN THOC2 CYFIP2 MEGF8 LRP1 MAEL CTNND2 C9orf72 CDH1 SOS1 EPHA8

6.75e-05119419626GO:0000902
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 AKAP6 KCNE2 DRD2 SLC5A10 TPCN2 SLC6A16 GPR35 NTSR1 SLC9C2 IBTK KCNQ4 PLCH2

6.93e-0592219622GO:0098662
GeneOntologyBiologicalProcesssecretion by cell

SYN3 LRRK2 NAPA BCL2L1 F2RL2 SNX19 KISS1R SYNJ1 ABCC8 MMP13 SEL1L EXOC6 DRD2 TPCN2 NTSR1 PORCN GRIK5 ACVR1C RFX3 TXLNA CADPS LRP1 C9orf72 CADPS2

7.67e-05106419624GO:0032940
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

KCNMB2 KCNH8 CCT8L2 KCNJ4 ABCC8 KCNAB1 AKAP6 KCNE2 SLC9C2 KCNQ4

7.88e-0523219610GO:0071805
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 BEST3 PKDREJ CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 AKAP6 KCNE2 DRD2 SLC5A10 TPCN2 SLC6A16 GPR35 NTSR1 SLC9C2 IBTK KCNQ4 PLCH2

1.05e-04101719623GO:0098660
GeneOntologyBiologicalProcessmonoatomic cation transport

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 PKDREJ KLHL3 CCT8L2 KCNJ4 ABCC8 SCN10A KCNAB1 SLC29A4 AKAP6 KCNE2 DRD2 SLC5A10 TPCN2 SLC6A16 GPR35 NTSR1 SLC9C2 IBTK PIEZO2 KCNQ4 PLCH2

1.06e-04115719625GO:0006812
GeneOntologyBiologicalProcesssignal release from synapse

SYN3 LRRK2 NAPA BCL2L1 SYNJ1 ABCC8 GRIK5 CADPS CADPS2

1.07e-041951969GO:0099643
GeneOntologyBiologicalProcessneurotransmitter secretion

SYN3 LRRK2 NAPA BCL2L1 SYNJ1 ABCC8 GRIK5 CADPS CADPS2

1.07e-041951969GO:0007269
GeneOntologyBiologicalProcessdevelopmental growth

TSHR CYFIP1 FDPS ASPM FGFR2 STRA6 MMP13 PLS1 AKAP6 DRD2 ACVR1C CYFIP2 TGFBR1 MEGF8 LRP1 KDM2A MAEL C9orf72 CDH1 IL6R SOS1

1.64e-0491119621GO:0048589
GeneOntologyBiologicalProcesssignal release

SYN3 LRRK2 NAPA BCL2L1 F2RL2 SNX19 KISS1R SYNJ1 ABCC8 DRD2 PORCN GRIK5 ACVR1C RFX3 CADPS LRP1 CADPS2

1.74e-0465319617GO:0023061
GeneOntologyBiologicalProcessregulation of urine volume

AKR1B1 NPR1 DRD2 HAS2

1.79e-04301964GO:0035809
GeneOntologyBiologicalProcesssynaptic vesicle exocytosis

LRRK2 NAPA BCL2L1 SYNJ1 GRIK5 CADPS CADPS2

1.95e-041251967GO:0016079
GeneOntologyBiologicalProcesssynaptic vesicle priming

NAPA SYNJ1 CADPS CADPS2

2.04e-04311964GO:0016082
GeneOntologyBiologicalProcesssecretion

SYN3 LRRK2 NAPA BCL2L1 F2RL2 SNX19 KISS1R SYNJ1 ABCC8 MMP13 SEL1L EXOC6 NPR1 DRD2 TPCN2 NTSR1 PORCN GRIK5 ACVR1C RFX3 TXLNA CADPS LRP1 C9orf72 CADPS2

2.44e-04122119625GO:0046903
GeneOntologyBiologicalProcessartery morphogenesis

ADGRF4 STRA6 LDLR TGFBR1 MEGF8 LRP1

2.47e-04921966GO:0048844
GeneOntologyBiologicalProcessorbitofrontal cortex development

FGFR2 DRD2

2.68e-0431962GO:0021769
GeneOntologyBiologicalProcesstight junction disassembly

ABCC8 TGFBR1

2.68e-0431962GO:1905071
GeneOntologyBiologicalProcesspositive regulation of tight junction disassembly

ABCC8 TGFBR1

2.68e-0431962GO:1905075
GeneOntologyBiologicalProcessregulation of tight junction disassembly

ABCC8 TGFBR1

2.68e-0431962GO:1905073
GeneOntologyBiologicalProcessregulation of membrane potential

KCNMB2 KCNH8 LRRK2 BCL2L1 SSH1 ABCC8 SCN10A AKAP6 KCNE2 DRD2 GPR35 CNTNAP1 NTSR1 GRIK5 PIEZO2

3.07e-0455919615GO:0042391
GeneOntologyBiologicalProcessepithelial cilium movement involved in determination of left/right asymmetry

OFD1 RFX3 MEGF8

3.53e-04151963GO:0060287
GeneOntologyBiologicalProcesspositive regulation of urine volume

NPR1 DRD2 HAS2

3.53e-04151963GO:0035810
GeneOntologyBiologicalProcessbranching morphogenesis of a nerve

LRRK2 FGFR2 DRD2

3.53e-04151963GO:0048755
GeneOntologyBiologicalProcessembryonic body morphogenesis

NCKAP1 CDON OFD1

3.53e-04151963GO:0010172
GeneOntologyBiologicalProcesspositive regulation of growth

TSHR CYFIP1 FDPS FGFR2 PLS1 AKAP6 DRD2 DERL2 TGFBR1 MEGF8 LRP1

4.18e-0433919611GO:0045927
GeneOntologyCellularComponentactivin receptor complex

ACVR1B ACVR1C TGFBR1

1.57e-0561953GO:0048179
GeneOntologyCellularComponentpotassium channel complex

KCNMB2 KCNJ4 ABCC8 KCNAB1 KCNE2 GRIK5 KCNQ4

5.46e-051041957GO:0034705
GeneOntologyCellularComponentmonoatomic ion channel complex

KCNMB2 KCNH8 BEST3 KCNJ4 ABCC8 SCN10A KCNAB1 AKAP6 KCNE2 TPCN2 PORCN GRIK5 KCNQ4

5.85e-0537819513GO:0034702
GeneOntologyCellularComponenttransmembrane transporter complex

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 BEST3 KCNJ4 ABCC8 SCN10A KCNAB1 AKAP6 KCNE2 TPCN2 PORCN GRIK5 KCNQ4

1.23e-0452319515GO:1902495
GeneOntologyCellularComponentSCAR complex

NCKAP1 CYFIP1 CYFIP2

1.65e-04121953GO:0031209
GeneOntologyCellularComponenttransporter complex

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 BEST3 KCNJ4 ABCC8 SCN10A KCNAB1 AKAP6 KCNE2 TPCN2 PORCN GRIK5 KCNQ4

2.12e-0455019515GO:1990351
GeneOntologyCellularComponentpresynapse

ATP6V1C1 ATP6V0A1 SYN3 ATR LRRK2 NAPA BCL2L1 CYFIP1 SYNJ1 ABCC8 SCN10A SLC29A4 DRD2 CNTNAP1 NTSR1 GRIK5 CADPS C9orf72 CADPS2 CDH1

2.44e-0488619520GO:0098793
GeneOntologyCellularComponentexocytic vesicle membrane

ATP6V1C1 ATP6V0A1 SYN3 ATR LRRK2 BCL2L1 ABCC8 DRD2

2.85e-041791958GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

ATP6V1C1 ATP6V0A1 SYN3 ATR LRRK2 BCL2L1 ABCC8 DRD2

2.85e-041791958GO:0030672
GeneOntologyCellularComponentcation channel complex

KCNMB2 KCNJ4 ABCC8 SCN10A KCNAB1 AKAP6 KCNE2 GRIK5 KCNQ4

3.76e-042351959GO:0034703
GeneOntologyCellularComponentglutamatergic synapse

SYN3 LRRK2 ADGRB2 NAPA SYNJ1 KCNJ4 SCN10A DRD2 CNTNAP1 PORCN GRIK5 CADPS LRP1 CTNND2 C9orf72 CADPS2 CDH1 KLHL17

6.67e-0481719518GO:0098978
GeneOntologyCellularComponentextrinsic component of organelle membrane

ATP6V1C1 SYN3 ATR CADPS

6.82e-04431954GO:0031312
GeneOntologyCellularComponentmembrane protein complex

KCNMB2 ATP6V1C1 ATP6V0A1 KCNH8 GPAA1 NAPA BEST3 ACVR1B SYNJ1 KCNJ4 ABCC8 SCN10A KCNAB1 SEL1L AKAP6 KCNE2 DRD2 TPCN2 PORCN GRIK5 ACVR1C TGFBR1 KCNQ4 LRP1 RNF139 CDH1 IL6R

7.49e-04149819527GO:0098796
GeneOntologyCellularComponentdistal axon

LRRK2 CYFIP1 SSH1 SYNJ1 EXOC6 DRD2 NTSR1 GRIK5 LRP1 C9orf72 CDH1 INPP5J

8.26e-0443519512GO:0150034
GeneOntologyCellularComponentplasma membrane protein complex

KCNMB2 ACVR1B SYNJ1 KCNJ4 ABCC8 SCN10A KCNAB1 KCNE2 DRD2 PORCN GRIK5 ACVR1C TGFBR1 KCNQ4 LRP1 CDH1 IL6R

1.13e-0378519517GO:0098797
GeneOntologyCellularComponentreceptor complex

TSHR ACVR1B ARNT2 FGFR2 NPR1 DRD2 PORCN GRIK5 ACVR1C LDLR TGFBR1 MST1R LRP1 IL6R

1.15e-0358119514GO:0043235
GeneOntologyCellularComponentperikaryon

LRRK2 KCNAB1 DRD2 AZIN2 NTSR1 GRIK5 CTNND2 C9orf72

1.21e-032231958GO:0043204
GeneOntologyCellularComponentapical part of cell

ATP6V1C1 MYO7A CA14 F2RL2 ASPM SLC29A4 KCNE2 SLC5A10 LDLR SLC22A12 TGFBR1 LRP1 CDH1 IL6R

1.38e-0359219514GO:0045177
GeneOntologyCellularComponentextrinsic component of synaptic vesicle membrane

ATP6V1C1 SYN3 ATR

1.58e-03251953GO:0098850
GeneOntologyCellularComponentvoltage-gated potassium channel complex

KCNMB2 KCNJ4 KCNAB1 KCNE2 KCNQ4

1.63e-03911955GO:0008076
GeneOntologyCellularComponentcell surface

SLAMF8 CFH FAM234A TSHR ACVR1B KISS1R FGFR2 IL17RB CDON ALPP KCNE2 NID2 NTSR1 ACVR1C LDLR TGFBR1 MST1R AOC3 LRP1 CDH1 IL6R

1.68e-03111119521GO:0009986
GeneOntologyCellularComponentaxon

CFH LRRK2 CYFIP1 SSH1 SYNJ1 SCN10A KCNAB1 CNTN4 EXOC6 DRD2 AZIN2 CNTNAP1 NTSR1 GRIK5 LRP1 C9orf72 CDH1 INPP5J

1.77e-0389119518GO:0030424
GeneOntologyCellularComponentterminal bouton

LRRK2 CYFIP1 SYNJ1 NTSR1 GRIK5

2.07e-03961955GO:0043195
GeneOntologyCellularComponentsynaptic vesicle

ATP6V1C1 ATP6V0A1 SYN3 ATR LRRK2 BCL2L1 ABCC8 DRD2 CADPS2

2.09e-033001959GO:0008021
GeneOntologyCellularComponentDerlin-1 retrotranslocation complex

SEL1L RNF139

2.34e-0381952GO:0036513
GeneOntologyCellularComponentplasma membrane raft

LRRK2 AKAP6 LDLR TGFBR1 HAS2 CDH1

2.60e-031471956GO:0044853
GeneOntologyCellularComponentsite of polarized growth

LRRK2 CYFIP1 SSH1 EXOC6 FRYL LRP1 C9orf72 INPP5J

2.66e-032531958GO:0030427
DomainGS_dom

ACVR1B ACVR1C TGFBR1

3.69e-0571933IPR003605
DomainGS

ACVR1B ACVR1C TGFBR1

3.69e-0571933PS51256
DomainTGF_beta_GS

ACVR1B ACVR1C TGFBR1

3.69e-0571933PF08515
DomainGS

ACVR1B ACVR1C TGFBR1

3.69e-0571933SM00467
DomainQuino_amine_DH_bsu

LRRK2 BRWD3 NID2 NBAS

6.99e-05221934IPR011044
DomainBTB-kelch_protein

KLHL2 KLHL3 KLHL34 KBTBD2 KLHL17

7.83e-05431935IPR017096
DomainKelch_1

KLHL2 KLHL3 KLHL34 KBTBD2 MEGF8 KLHL17

8.53e-05701936PF01344
DomainKelch_1

KLHL2 KLHL3 KLHL34 KBTBD2 MEGF8 KLHL17

8.53e-05701936IPR006652
DomainCytoplasmic_FMR1-int

CYFIP1 CYFIP2

1.06e-0421932IPR008081
DomainCAPS

CADPS CADPS2

1.06e-0421932IPR033227
DomainFragX_IP

CYFIP1 CYFIP2

1.06e-0421932PF05994
DomainActivin_recp

ACVR1B ACVR1C TGFBR1

1.24e-04101933PF01064
DomainActivin_recp

ACVR1B ACVR1C TGFBR1

1.24e-04101933IPR000472
DomainTGFB_receptor

ACVR1B ACVR1C TGFBR1

2.23e-04121933IPR000333
DomainRFX1_trans_act

RFX2 RFX3

3.17e-0431932IPR007668
DomainRFX1_trans_act

RFX2 RFX3

3.17e-0431932PF04589
DomainKelch

KLHL2 KLHL3 KLHL34 KBTBD2 KLHL17

3.29e-04581935SM00612
DomainGal_Oxase/kelch_b-propeller

KLHL2 KLHL3 KBTBD2 MEGF8 KLHL17

3.56e-04591935IPR011043
DomainLdl_recept_b

NID2 LDLR LRP1

3.64e-04141933PF00058
DomainLDLRB

NID2 LDLR LRP1

3.64e-04141933PS51120
DomainBACK

KLHL2 KLHL3 KLHL34 KBTBD2 KLHL17

3.85e-04601935SM00875
DomainBACK

KLHL2 KLHL3 KLHL34 KBTBD2 KLHL17

4.16e-04611935IPR011705
DomainBACK

KLHL2 KLHL3 KLHL34 KBTBD2 KLHL17

4.16e-04611935PF07707
DomainBTB

KLHL2 KLHL3 KLHL34 ABTB2 KBTBD2 IBTK KLHL17

4.28e-041311937PF00651
DomainLY

NID2 LDLR LRP1

4.51e-04151933SM00135
DomainLDLR_classB_rpt

NID2 LDLR LRP1

4.51e-04151933IPR000033
DomainARM-like

SMG1 ATR LRRK2 NBEAL2 ASPM MROH7 IPO8 FRYL MROH1 CTNND2

5.19e-0427019310IPR011989
DomainDUF1394

CYFIP1 CYFIP2

6.29e-0441932IPR009828
DomainDUF1394

CYFIP1 CYFIP2

6.29e-0441932PF07159
DomainFATC

SMG1 ATR

1.04e-0351932PF02260
DomainDUF1041

CADPS CADPS2

1.04e-0351932SM01145
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

DPF1 FAM234A ATP6V0A1 GPAA1 TSHR YIF1A KCNJ4 ABCC8 USP4 SETD3 AKR1B1 DRD2 TPCN2 GPR35 CNTNAP1 CYFIP2 PLCH2 RXFP4 CTNND2

2.04e-086971971928298427
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MYO7A ADGRB2 COMTD1 ELAC2 ADCY7 MDN1 SSH1 SYNJ1 NBEAL2 FGFR2 ABTB2 TRAF7 OFD1 KMT5C NTSR1 FRYL REV3L LDLR DHX30 MST1R MROH1 MEGF8 PRRT4 KLHL17

2.05e-0811051972435748872
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

NCKAP1 ADGRB2 CYFIP1 SYNJ1 UBE2N KCNJ4 KCNAB1 CNTNAP1 GRIK5 CYFIP2 LRP1 CTNND2

2.39e-082511971227507650
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

CFH KLHL2 MBTPS1 BEST3 CA14 ADCY7 HENMT1 MDN1 SSH1 SYNJ1 FDPS FOXO4 ADGRF4 MED27 PLS1 SEL1L AKAP6 SLC5A10 TPCN2 YIPF4 ST3GAL4 REV3L MST1R TIGD2 CADPS2

9.56e-0812931972515342556
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

KCNMB2 SMG1 MYO7A FER1L6 PLEKHH1 KLHL3 CYFIP1 MDN1 UBE2N EXOC6 AZIN2 DERL2 REV3L TEFM MEGF8 CTNND2 HELLS

1.61e-076381971731182584
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

CFH MBTPS1 FAM234A ATP6V0A1 GPAA1 ATR ELAC2 CDON SEL1L TRAF7 NPR1 YIPF4 CNTNAP1 DERL2 RNF213 ST3GAL4 LDLR SPAG5 TGFBR1 MST1R TXNDC15 MEGF8 LRP1

3.84e-0712011972335696571
Pubmed

Aldose reductase-mediated phosphorylation of p53 leads to mitochondrial dysfunction and damage in diabetic platelets.

BCL2L1 AKR1B1 LDLR

7.13e-074197324474649
Pubmed

Interchangeable functions of Arabidopsis PIROGI and the human WAVE complex subunit SRA1 during leaf epidermal development.

NCKAP1 CYFIP1 CYFIP2

7.13e-074197315294869
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

ATP6V0A1 KCNH8 BCL2L1 ACVR1B GALNT16 KLHL3 MAPK12 SSH1 UBE2N USP4 MMP13 DNAH10 LDLR MAP4K1 LRP1 KDM2A KLHL17

1.04e-067301971734857952
Pubmed

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

ATR FDPS NBEAL2 SEL1L EXOC6 IPO8 IARS1 RNF213 SOS1

1.11e-06183197923956138
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

KCNMB2 KCNH8 KCNJ4 ABCC8 SCN10A KCNAB1 KCNE2 KCNQ4

1.37e-06139197816985003
Pubmed

LRP1 Deficiency in Vascular SMC Leads to Pulmonary Arterial Hypertension That Is Reversed by PPARγ Activation.

LDLR TGFBR1 LRP1

3.54e-066197331023188
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

CFH MYO7A ELAC2 CYFIP1 MDN1 NBEAL2 COQ9 ASPM MROH7 USP4 ABTB2 SEL1L KCNE2 USP30 GPR35 FRYL CYFIP2 TTLL11 KDM8 CDH1 ACTL10

8.71e-0612421972130973865
Pubmed

Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis.

ACVR1B ACVR1C TGFBR1

9.82e-068197316845371
Pubmed

Abi1 is essential for the formation and activation of a WAVE2 signalling complex.

NCKAP1 CYFIP1 CYFIP2

2.09e-0510197315048123
Pubmed

SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming.

NAPA CADPS CADPS2

2.09e-0510197321040848
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

FGFR2 MMP13 CDH1

2.86e-0511197316607638
Pubmed

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

ATR BCL2L1 MAPK12 NPR1 GRIK5 MST1R KCNQ4 MAP4K1 AOC3

3.06e-05276197928319085
Pubmed

CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic beta cells.

CADPS CADPS2

3.19e-052197218177725
Pubmed

R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice.

LRRK2 DRD2

3.19e-052197219667187
Pubmed

Low density lipoprotein receptor-related protein polymorphisms are not risk factors for venous thromboembolism.

LDLR LRP1

3.19e-052197217889283
Pubmed

Genome-wide association of breast cancer: composite likelihood with imputed genotypes.

FGFR2 NTSR1

3.19e-052197220959865
Pubmed

Upregulation of hepatic LDL transport by n-3 fatty acids in LDL receptor knockout mice.

LDLR LRP1

3.19e-052197211971949
Pubmed

Ubiquitin-specific protease 4 promotes metastasis of hepatocellular carcinoma by increasing TGF-β signaling-induced epithelial-mesenchymal transition.

USP4 TGFBR1

3.19e-052197230335615
Pubmed

Comprehensive genetic study of fatty acids helps explain the role of noncoding inflammatory bowel disease associated SNPs and fatty acid metabolism in disease pathogenesis.

LRRK2 CBS

3.19e-052197229549916
Pubmed

LRP: role in vascular wall integrity and protection from atherosclerosis.

LDLR LRP1

3.19e-052197212690199
Pubmed

Disruption of GPR35 Signaling in Bone Marrow-Derived Cells Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice.

GPR35 LDLR

3.19e-052197234201526
Pubmed

Bcl-xL-mediated antioxidant function abrogates the disruption of mitochondrial dynamics induced by LRRK2 inhibition.

LRRK2 BCL2L1

3.19e-052197226435084
Pubmed

Submicroscopic deletion in 7q31 encompassing CADPS2 and TSPAN12 in a child with autism spectrum disorder and PHPV.

TSPAN12 CADPS2

3.19e-052197221626674
Pubmed

Selective homocysteine lowering gene transfer improves infarct healing, attenuates remodelling, and enhances diastolic function after myocardial infarction in mice.

CBS LDLR

3.19e-052197223675503
Pubmed

Knockdown of REV3 synergizes with ATR inhibition to promote apoptosis induced by cisplatin in lung cancer cells.

ATR REV3L

3.19e-052197228075014
Pubmed

CAPS-1 requires its C2, PH, MHD1 and DCV domains for dense core vesicle exocytosis in mammalian CNS neurons.

CADPS CADPS2

3.19e-052197228883501
Pubmed

Lack of Tgfbr1 and Acvr1b synergistically stimulates myofibre hypertrophy and accelerates muscle regeneration.

ACVR1B TGFBR1

3.19e-052197235323108
Pubmed

Severe hyperhomocysteinemia promotes bone marrow-derived and resident inflammatory monocyte differentiation and atherosclerosis in LDLr/CBS-deficient mice.

CBS LDLR

3.19e-052197222628578
Pubmed

Inactivation of Semicarbazide-Sensitive Amine Oxidase Stabilizes the Established Atherosclerotic Lesions via Inducing the Phenotypic Switch of Smooth Muscle Cells.

LDLR AOC3

3.19e-052197227043821
Pubmed

Hepatocyte growth factor/c-Met signalling is important for the selection of transplanted hepatocytes.

HGF MST1R

3.19e-052197222287599
Pubmed

Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson's disease.

LRRK2 DRD2

3.19e-052197229434188
Pubmed

CAPS facilitates filling of the rapidly releasable pool of large dense-core vesicles.

CADPS CADPS2

3.19e-052197218495893
Pubmed

Recovery and maintenance of nephrin expression in cultured podocytes and identification of HGF as a repressor of nephrin.

HGF NPHS1

3.19e-052197217244893
Pubmed

Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition.

LRRK2 TPCN2

3.19e-052197225416817
Pubmed

Dopamine D2 receptor signaling dynamics of dopamine D2-neurotensin 1 receptor heteromers.

DRD2 NTSR1

3.19e-052197223624386
Pubmed

Cytoplasmic FMR1 interacting protein (CYFIP) family members and their function in neural development and disorders.

CYFIP1 CYFIP2

3.19e-052197234327661
Pubmed

An extrahepatic receptor-associated protein-sensitive mechanism is involved in the metabolism of triglyceride-rich lipoproteins.

LDLR LRP1

3.19e-052197210575007
Pubmed

CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons.

CADPS CADPS2

3.19e-052197225719439
Pubmed

Zebrafish Dpr2 inhibits mesoderm induction by promoting degradation of nodal receptors.

ACVR1B TGFBR1

3.19e-052197215459392
Pubmed

LDL-receptor mRNA expression in men is downregulated within an hour of an acute fat load and is influenced by genetic polymorphism.

LDLR LRP1

3.19e-052197217709443
Pubmed

Cyfip1 Haploinsufficiency Increases Compulsive-Like Behavior and Modulates Palatable Food Intake in Mice: Dependence on Cyfip2 Genetic Background, Parent-of Origin, and Sex.

CYFIP1 CYFIP2

3.19e-052197231324746
Pubmed

Collagenase-3 binds to a specific receptor and requires the low density lipoprotein receptor-related protein for internalization.

MMP13 LRP1

3.19e-052197210514495
Pubmed

Integrating Mouse and Human Genetic Data to Move beyond GWAS and Identify Causal Genes in Cholesterol Metabolism.

SESN1 LDLR

3.19e-052197232197071
Pubmed

Different dysregulations of CYFIP1 and CYFIP2 in distinct types of dementia.

CYFIP1 CYFIP2

3.19e-052197238128786
Pubmed

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson's disease.

LRRK2 SYNJ1

3.19e-052197227794539
Pubmed

Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms.

ACVR1B TGFBR1

3.19e-052197230804470
Pubmed

Altered expression of E-cadherin by hepatocyte growth factor and effect on the prognosis of nasopharyngeal carcinoma.

HGF CDH1

3.19e-052197220131016
Pubmed

CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins.

CADPS CADPS2

3.19e-052197218022372
Pubmed

Cytoplasmic FMRP interacting protein 1/2 (CYFIP1/2) expression analysis in autism.

CYFIP1 CYFIP2

3.19e-052197229752658
Pubmed

Maternal Kdm2a-mediated PI3K/Akt signaling and E-cadherin stimulate the morula-to-blastocyst transition revealing crucial roles in early embryonic development.

KDM2A CDH1

3.19e-052197237356280
Pubmed

Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants.

LDLR LRP1

3.19e-05219729449704
Pubmed

Two distinct secretory vesicle-priming steps in adrenal chromaffin cells.

CADPS CADPS2

3.19e-052197220855507
Pubmed

LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome.

LDLR LRP1

3.19e-052197217505534
Pubmed

Arabidopsis GNARLED encodes a NAP125 homolog that positively regulates ARP2/3.

NCKAP1 CYFIP1

3.19e-052197215296760
Pubmed

C9orf72 hexanucleotide repeat expansion and Guam amyotrophic lateral sclerosis-Parkinsonism-dementia complex.

LRRK2 C9orf72

3.19e-052197223588498
Pubmed

Low-density-lipoprotein-receptor-related protein (LRP) interacts with a GTP-binding protein.

GTPBP1 LRP1

3.19e-05219729820815
Pubmed

C57BL/6N mutation in cytoplasmic FMRP interacting protein 2 regulates cocaine response.

CYFIP1 CYFIP2

3.19e-052197224357318
Pubmed

Neurotensin NTS1-dopamine D2 receptor-receptor interactions in putative receptor heteromers: relevance for Parkinson's disease and schizophrenia.

DRD2 NTSR1

3.19e-052197225175457
Pubmed

Striatal D2 receptors regulate dendritic morphology of medium spiny neurons via Kir2 channels.

KCNJ4 DRD2

3.19e-052197222396414
Pubmed

Differential expression of KCNQ4 in inner hair cells and sensory neurons is the basis of progressive high-frequency hearing loss.

MYO7A KCNQ4

3.19e-052197216207888
Pubmed

The WAVE regulatory complex is inhibited.

NCKAP1 CYFIP1

3.19e-052197219363480
Pubmed

Protein interactome and cell-type expression analyses reveal that cytoplasmic FMR1-interacting protein 1 (CYFIP1), but not CYFIP2, associates with astrocytic focal adhesion.

CYFIP1 CYFIP2

3.19e-052197235567753
Pubmed

Regulation of dense core vesicle release from PC12 cells by interaction between the D2 dopamine receptor and calcium-dependent activator protein for secretion (CAPS).

DRD2 CADPS

3.19e-052197215857609
Pubmed

A Large-scale genetic association study of esophageal adenocarcinoma risk.

ATR BCL2L1 ABCC8 IL17RB REV3L CBS TGFBR1 CDH1 IL6R MUTYH

3.51e-053511971020453000
Pubmed

Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16 to trigger its nuclear localization.

ACVR1B UBE2N TGFBR1

3.79e-0512197325872870
Pubmed

Signaling through the TGF beta-activin receptors ALK4/5/7 regulates testis formation and male germ cell development.

ACVR1B ACVR1C TGFBR1

3.79e-0512197323342175
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CFH ATP6V0A1 NAPA BRWD3 PLEKHH1 SYNJ1 AKAP6 CNTN4 CNTNAP1 REV3L INTS8 CBS DHX30 TXNDC15 ARHGEF10 CADPS LRP1 CTNND2 CADPS2 SOS1

4.63e-0512851972035914814
Pubmed

TBX2 specifies and maintains inner hair and supporting cell fate in the Organ of Corti.

MYO7A KCNQ4 CDH1

4.91e-0513197336494345
Pubmed

Update on the Kelch-like (KLHL) gene family.

KLHL2 KLHL3 KLHL34 KLHL17

8.58e-0541197423676014
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

GPR82 ADGRB2 QRFPR ADGRF4 RXFP4

8.89e-0579197512679517
Pubmed

Hepatic remnant lipoprotein clearance by heparan sulfate proteoglycans and low-density lipoprotein receptors depend on dietary conditions in mice.

LDLR LRP1

9.54e-053197223846497
Pubmed

Increased expression of delta-catenin/neural plakophilin-related armadillo protein is associated with the down-regulation and redistribution of E-cadherin and p120ctn in human prostate cancer.

CTNND2 CDH1

9.54e-053197216226102
Pubmed

Inactivation of the LRP1 intracellular NPxYxxL motif in LDLR-deficient mice enhances postprandial dyslipidemia and atherosclerosis.

LDLR LRP1

9.54e-053197219667105
Pubmed

Low-density lipoprotein receptor-related protein 1 prevents early atherosclerosis by limiting lesional apoptosis and inflammatory Ly-6Chigh monocytosis: evidence that the effects are not apolipoprotein E dependent.

LDLR LRP1

9.54e-053197221730304
Pubmed

Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains.

RFX2 RFX3

9.54e-053197210330134
Pubmed

Ciliogenic RFX transcription factors regulate FGF1 gene promoter.

RFX2 RFX3

9.54e-053197222415835
Pubmed

Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; the effect of pharmacological targeting TGFβ receptor I kinase.

TGFBR1 CDH1

9.54e-053197225421310
Pubmed

Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis.

SCN10A PIEZO2

9.54e-053197237120427
Pubmed

P2X7 receptor stimulates breast cancer cell invasion and migration via the AKT pathway.

MMP13 CDH1

9.54e-053197225976617
Pubmed

RAGE, LDL receptor, and LRP1 expression in the brains of SAMP8.

LDLR LRP1

9.54e-053197219539695
Pubmed

Drosophila regulatory factor X is necessary for ciliated sensory neuron differentiation.

RFX2 RFX3

9.54e-053197212403718
Pubmed

Proprotein convertase subtilisin/kexin type 9 (PCSK9) can mediate degradation of the low density lipoprotein receptor-related protein 1 (LRP-1).

LDLR LRP1

9.54e-053197223675525
Pubmed

Role of LRRK2 in the regulation of dopamine receptor trafficking.

LRRK2 DRD2

9.54e-053197228582422
Pubmed

Secretory vesicle priming by CAPS is independent of its SNARE-binding MUN domain.

CADPS CADPS2

9.54e-053197225437547
Pubmed

LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages.

LDLR LRP1

9.54e-053197226061292
Pubmed

Interplay of RFX transcription factors 1, 2 and 3 in motile ciliogenesis.

RFX2 RFX3

9.54e-053197232725242
Pubmed

PAR-3 knockdown enhances adhesion rate of PANC-1 cells via increased expression of integrinαv and E-cadherin.

F2RL2 CDH1

9.54e-053197224699825
Pubmed

Cross-talk between the proto-oncogenes Met and Ron.

HGF MST1R

9.54e-053197210871856
Pubmed

Hematopoietic stem/progenitor cells directly contribute to arteriosclerotic progression via integrin β2.

LDLR LRP1

9.54e-053197225546260
Pubmed

TEFM (c17orf42) is necessary for transcription of human mtDNA.

TEFM DHX30

9.54e-053197221278163
Pubmed

LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling.

LDLR LRP1

9.54e-053197218990694
Pubmed

Deletion of macrophage LDL receptor-related protein increases atherogenesis in the mouse.

LDLR LRP1

9.54e-053197217303763
Pubmed

The deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function.

USP4 HAS2

9.54e-053197228604766
Pubmed

Preservations of nephrin and synaptopodin by recombinant hepatocyte growth factor in podocytes for the attenuations of foot process injury and albuminuria in nephritic mice.

HGF NPHS1

9.54e-053197221342325
GeneFamilyType 1 receptor serine/threonine kinases

ACVR1B ACVR1C TGFBR1

1.84e-0571483345
GeneFamilyBasic leucine zipper proteins|BTB domain containing

KLHL2 KLHL3 KLHL34 ABTB2 KBTBD2 IBTK KLHL17

1.18e-041341487861
GeneFamilyKelch like|BTB domain containing

KLHL2 KLHL3 KLHL34 KLHL17

3.79e-04421484617
GeneFamilyPeptide receptors

QRFPR KISS1R

1.36e-0371482220
GeneFamilyRegulatory factor X family

RFX2 RFX3

1.80e-03814821153
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMB2 HGF IL36B GALNT16 KCNE2 FAR2 KCNQ4 RXFP4 CDH1

3.56e-081571979ed9c9feefc06c9536c03bedbc3397a2ee492a78e
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMB2 HGF IL36B GALNT16 KCNE2 FAR2 KCNQ4 RXFP4 CDH1

3.56e-081571979fddcb24776b9f86e000208bae54541b15b2adefd
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

KCNH8 GALNT16 ABCC8 ARNT2 SLC29A4 NPHS1 GRIK5 KCNQ4

8.95e-07169197896a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

LRRK2 FGFR2 CDON CNTN4 LDLR TMC5 CADPS2 CDH1

1.50e-061811978c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TSPAN12 CFH ADGRB2 ARNT2 NPHS1 NID2 NPR1 CDH1

1.99e-061881978b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TSPAN12 CFH ADGRB2 ARNT2 NPHS1 NID2 NPR1 CDH1

1.99e-061881978874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNJ1 ABCC8 FRYL REV3L LDLR CYFIP2 CADPS IL6R

2.61e-0619519783e519cffa6144a62b06124642a14c9ff39b76554
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

AADAC LRRK2 FGFR2 PHIP CDON CYFIP2 CADPS2 CDH1

2.82e-06197197844a59dfb889577b3160a5b13ada1276771a00241
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

F2RL2 KLHL34 STRA6 DRD2 MST1R TMC5 PRRT4

6.22e-06156197727590a4d2b419644966f0037c67c761fc275e0aa
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPF1 AADAC NLN ARNT2 ABTB2 LDLR KLHL17

7.65e-0616119770d863d7d369391dd6148e1de6d6f8033dcb8fe0f
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH F2RL2 FER1L6 FGFR2 MMP13 ST3GAL4 CDH1

7.65e-0616119779cfbbcd38ec2e75376bbc26001964b6991ad0e21
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CFH NCKAP1 EML5 FGFR2 PLS1 XKR6 TMC5

7.97e-0616219772259e9536147e9cdee772e3a30ba7d104573262c
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MCM7 FER1L6 AKR1B1 PLS1 AKAP6 SPAG5 LRP1

8.30e-061631977360cd65decda24853124f33a174f5224d7f3ce23
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MCM7 FER1L6 AKR1B1 PLS1 AKAP6 SPAG5 LRP1

8.30e-061631977b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPF1 BEST3 STRA6 AZIN2 ACVR1C INTS9 INPP5J

9.35e-06166197760060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPF1 BEST3 STRA6 AZIN2 ACVR1C INTS9 INPP5J

9.35e-061661977ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPF1 BEST3 STRA6 AZIN2 ACVR1C INTS9 INPP5J

9.35e-0616619774586d6725403f879fc96f67be579022587ce1906
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CFH NCKAP1 EML5 FGFR2 PLS1 XKR6 TMC5

9.35e-06166197789e2b8453180983533faccb4275867861876d7ee
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

TSPAN12 CFH ARNT2 FGFR2 CNTN4 NID2 NPR1

1.18e-05172197736a96714a0eb6ac438648135336c9791881ddadb
ToppCellfacs-Marrow-KLS-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYN3 KCNAB1 PLS1 SEL1L PORCN ARHGEF10 EPHA8

1.22e-051731977295bfe1efa648173c2d5981025bc61c576baf53f
ToppCellHealthy_Control-Lymphoid-NK-CD8_T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CA14 F2RL2 KISS1R MAPK12 GML GPR35 PLCH2

1.27e-0517419775dddb822fa51b4020e4d9318acacd19c726091d6
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MCM7 PLEKHH1 ASPM ARTN SPAG5 MAP4K1 HELLS

1.32e-0517519776b4e841bde6cfa4956e1a0231672cea20f11210c
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 EML5 FGFR2 LDLR CYFIP2 CADPS2 CDH1

1.82e-051841977ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

SHPRH SEL1L RNF213 FRYL LDLR NBAS HELLS

1.89e-051851977a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

AADAC LRRK2 CNTN4 XKR6 TMC5 CADPS2 CDH1

1.95e-0518619772ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGF BEST3 ASPM KCNAB1 FGFR2 PIEZO2 INPP5J

2.02e-051871977d413fb4b1531b297af5012a392b88128510c2de8
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPAN12 LRRK2 SSH1 ARNT2 SHPRH ANAPC5 INTS9

2.09e-0518819776468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPAN12 LRRK2 SSH1 ARNT2 SHPRH ANAPC5 INTS9

2.09e-0518819777a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPAN12 LRRK2 SSH1 ARNT2 SHPRH ANAPC5 INTS9

2.09e-0518819779cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRK2 ADGRF4 FGFR2 LDLR CADPS2 CDH1

2.17e-0512719765b0adbcafad31a6759c9bdce2f7f9591a8edc450
ToppCellControl-Epithelial_alveolar-Mes-Like-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AADAC CA14 CDON DNAH10 GRIK5 SPAG5

2.17e-051271976556aaf88719c83f307fa50dfac151136ed05c8ad
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma-B_plasmablast|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TSHR KISS1R CNTNAP1 ARTN PLCH2

2.20e-05761975df1c29cf88b1957e210058e172683f78a1eea2bd
ToppCell356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

HGF MYO7A NLN CYFIP1 AKR1B1 GRIK5 TGFBR1

2.24e-051901977d541e076137cf7334bdb0ed69db2f9a27c668c65
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

LRRK2 FGFR2 CNTN4 LDLR TMC5 CADPS2 CDH1

2.31e-051911977e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellfacs-Pancreas|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMB2 EML5 ABCC8 CYFIP2 CADPS CTNND2 IL6R

2.31e-051911977d48e5f67d384226add7d7fb2a124954136e09a82
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

MBTPS1 SEL1L RNF213 FRYL LDLR NBAS HELLS

2.31e-0519119779454f642c3621370fa23640b631301346b300950
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

LRRK2 FGFR2 CNTN4 LDLR TMC5 CADPS2 CDH1

2.39e-051921977499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

LRRK2 FGFR2 CNTN4 LDLR TMC5 CADPS2 CDH1

2.39e-051921977efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 GPR82 YIPF4 RNF213 FRYL ARTN RFX3

2.47e-0519319779337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell10x5'v1-week_14-16-Endothelial-stroma-proliferating_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TSPAN12 F2RL2 QRFPR NPR1 PIEZO2 AOC3 CADPS2

2.56e-0519419778a4be91414a2e69dd410aa75791f16008204c9a1
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC8 FRYL REV3L LDLR CYFIP2 CADPS IL6R

2.64e-0519519777796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NCKAP1 FER1L6 PLS1 ARTN MISP TMC5 CDH1

2.73e-0519619773e99a367b7d817e1f1221450fcec20ad7a7c7a2a
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NCKAP1 FER1L6 PLS1 ARTN MISP TMC5 CDH1

2.73e-0519619771efacc37bbfbd05b5d4db3dd10f6d9a238d23e31
ToppCellNS-moderate-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFH NCKAP1 FER1L6 PLEKHH1 FGFR2 PLS1 CDH1

2.73e-05196197770384c1da9baed843f414cfd1403ddd586a2db07
ToppCellRA-02._Fibroblast_II|World / Chamber and Cluster_Paper

CFH SYN3 ABTB2 CNTN4 ST3GAL4 REV3L HAS2

2.73e-051961977e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NCKAP1 FER1L6 PLS1 ARTN MISP TMC5 CDH1

2.82e-05197197708b371309cd790b171ed76cabc7d910e71cd2835
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LRRK2 FDPS FGFR2 LDLR CYFIP2 CADPS2 CDH1

2.82e-0519719771638959d7aecb9fc5285eb7e4a3103ca437989e2
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LRRK2 EML5 FGFR2 LDLR CYFIP2 CADPS2 CDH1

2.82e-0519719771485933986921ff45669d9b7501c8d17050b3e97
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LRRK2 FDPS FGFR2 LDLR CYFIP2 CADPS2 CDH1

2.82e-051971977ad6f047d003c08413264f39a30ba0f7639a257cd
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

NCKAP1 FER1L6 PLS1 ARTN MISP TMC5 CDH1

2.82e-0519719779f49feee38647bbf964974aac96fa75602186b5c
ToppCellLPS_anti-TNF-Epithelial_alveolar|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LRRK2 FDPS FGFR2 LDLR CYFIP2 CADPS2 CDH1

2.91e-05198197753e9ed1b19cb26be58da0f37057caca0cdfaabeb
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / Treatment groups by lineage, cell group, cell type

LRRK2 FDPS FGFR2 LDLR CYFIP2 CADPS2 CDH1

2.91e-051981977d087e738d69ca9853553fde46d4e7a8906439d32
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LRRK2 FDPS FGFR2 LDLR CYFIP2 CADPS2 CDH1

2.91e-051981977c4e7512f0e1d115f2be8acae6048eda8b6b640b2
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

AADAC LRRK2 FGFR2 LDLR CYFIP2 CADPS2 CDH1

2.91e-051981977aa80315395cb5dffc25927c8a77cd2037aea8772
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPF1 COMTD1 FER1L6 MDN1 NPHS1 RXFP4

2.94e-05134197664979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

HGF PHEX CNTN4 NID2 REV3L LRP1 HAS2

3.01e-05199197706a7d874ff7c4616577f6e59d3118717a8c47c00
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

HGF PHEX CNTN4 NID2 REV3L LRP1 HAS2

3.01e-051991977a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRRK2 ABCC8 ARNT2 IL17RB LDLR CYFIP2 LRP1

3.01e-05199197719a97e27a4758e794ce7246d295e112b47931a48
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PHEX CNTN4 NID2 REV3L LDLR LRP1 HAS2

3.01e-0519919778b86c69aaf60feff53aa782559cfece7342a23de
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

HGF PHEX CNTN4 NID2 REV3L LRP1 HAS2

3.01e-051991977ba586690f88fd051f449753bfe7603a2cb431782
ToppCellCOVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil|COVID-19_Mild / Disease, condition lineage and cell class

MCM7 ASPM FGFR2 FAR2 CDH1 PRRT4 HELLS

3.01e-051991977e222b90caf45904d8f763574e7b6aac13333df92
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1|Neuronal / cells hierarchy compared to all cells using T-Statistic

HGF BEST3 ASPM KCNAB1 FGFR2 PIEZO2 INPP5J

3.11e-052001977fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

HGF BEST3 ASPM KCNAB1 FGFR2 PIEZO2 INPP5J

3.11e-0520019774a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

HGF BEST3 ASPM KCNAB1 FGFR2 PIEZO2 INPP5J

3.11e-052001977c6eda342ea0cb37d71d89dbb8d11e819e0745172
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Serpinb1a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CA14 PLEKHH1 RASGRP3 FGFR2 PLS1 ARHGEF10

3.33e-051371976ca8fdbe66a854e6283b22179ec9359ea9e86cd8e
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

BRWD3 NPHS1 FRYL MST1R ACTL10 SOS1

5.53e-051501976744050a1b665c6989f37141348af3df7579a73c9
ToppCelldroplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLAMF8 GPR82 CYFIP1 MMP13 CYB5RL INPP5J

7.38e-0515819769a6d9b541446a6aa9f8ed040b330dbb5c6447076
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKDREJ HENMT1 SCN10A KCNAB1 DNAH10 SLC22A12

7.38e-0515819768c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCelldroplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLAMF8 GPR82 CYFIP1 MMP13 CYB5RL INPP5J

7.38e-0515819762438713d2a7e32c647ab3384237ed614f4ec8fec
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKDREJ HENMT1 SCN10A KCNAB1 DNAH10 SLC22A12

7.38e-051581976f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AADAC ARNT2 DNAH10 PCDHGA9 PLCH2 OTUD7A

7.91e-051601976f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCell5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-EECs|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPF1 ABCC8 SLC29A4 XKR6 RFX3 CADPS

8.47e-051621976478cf560ef33c5c324142c76417447d4a571a2c9
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Spp1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TSHR PKDREJ DRD2 MISP

9.50e-0554197498b31718fa200432cf86b59a52484da101219f96
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Spp1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TSHR PKDREJ DRD2 MISP

9.50e-05541974872e7374dac64be2c8ebe71e88a2ec6814168d89
ToppCelldroplet-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLAMF8 CFH FAM234A GPR35 LRP1 IL6R

9.69e-051661976f751cbd01d4978ded7755874ab60504f6291afd7
ToppCelldroplet-Lung-nan-18m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR82 F2RL2 EML5 S100PBP SPAG5 HELLS

1.03e-04168197696f7411474edd673b8d3ee6b8a8bb185c246daaf
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFH ARNT2 FGFR2 NPHS1 CNTN4 NID2

1.03e-041681976a086c306be430adf0632ba53e98cd8014d2de330
ToppCelldroplet-Thymus-nan-18m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLAMF8 MMP13 MISP MEGF8 CADPS CADPS2

1.07e-0416919764ac21e8199de4b6917eacadc56fffc6d886ee643
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

KCNH8 BEST3 ABCC8 SLC29A4 GRIK5 CADPS

1.07e-041691976b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCelldroplet-Spleen-nan-21m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH KCNE2 ST3GAL4 PIEZO2 LRP1 CDH1

1.14e-0417119769498c35b2a2c3a339dc8c5d49c8ec20d8ad52753
ToppCellCOVID-19_Convalescent-cDC|COVID-19_Convalescent / Disease condition and Cell class

SLAMF8 F2RL2 MAGEF1 KCNAB1 DNAH10 CDH1

1.14e-0417119769ccaa9f1629818b0f63a5d930ee78c01e04cd98d
ToppCelldroplet-Spleen-nan-21m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH KCNE2 ST3GAL4 PIEZO2 LRP1 CDH1

1.14e-041711976db544252f98e073e5bb4bec4a110cd58e6434435
ToppCellCOVID-19_Convalescent-cDC-|COVID-19_Convalescent / Disease condition and Cell class

SLAMF8 F2RL2 MAGEF1 KCNAB1 DNAH10 CDH1

1.14e-041711976fb5fae8b3adafcbb7c5618d887966b418355ed4d
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DPF1 MCM7 ANAPC5 SPAG5 PTPDC1 HELLS

1.18e-0417219762b6cd84c946b1e800caba452ae70145ea285fec1
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLAMF8 CFH MCM7 F2RL2 EML5 HELLS

1.25e-04174197609b091e24317c3f7bac043f04762a533e30793de
ToppCellLA-04._Ventricular_Cardiomyocyte_I|LA / Chamber and Cluster_Paper

AADAC QRFPR KCNJ4 CADPS CTNND2

1.29e-04110197534dcd1e1e16e8b6088ff9a7a40532e8bd000c121
ToppCellP28-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRRK2 FDPS FGFR2 KCNE2 LDLR CDH1

1.29e-0417519768a4ed775ff973123dbcfe9c809959d11a62450c9
ToppCellwk_15-18-Mesenchymal-Chondrocyte-intermediate_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CA14 FGFR2 ABTB2 CNTN4 DRD2 NTSR1

1.29e-041751976a84965d28438a4228d841b357c2cd75cf4b59a63
ToppCelldroplet-Marrow-nan-24m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLAMF8 CFH FAM234A GPR35 LRP1 IL6R

1.33e-041761976eddac2ba68d234e3f56f4ca0e11c19bc0e95b6e1
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNMB2 ABCC8 ARNT2 SLC29A4 CADPS RXFP4

1.33e-041761976fb718a6b07aa5d56600263280afa530bcb63db42
ToppCellPND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

F2RL2 NBEAL2 PLS1 EXOC6 XKR6 TTLL11

1.42e-041781976cb91558469ae0748106fb0b6d702edb0ff21a884
ToppCellPND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

F2RL2 NBEAL2 PLS1 EXOC6 XKR6 TTLL11

1.42e-04178197663f5880a5b514e20ef2c07a6a9cb8df34e6cede5
ToppCellPND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

F2RL2 NBEAL2 PLS1 EXOC6 XKR6 TTLL11

1.42e-04178197682c84f8b8a7e6a3d3be3351b348a37143279c100
ToppCellPSB-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IL17RB GPR35 RENBP GRIK5 CADPS HAS2

1.42e-04178197645bdbb96094c97756e1b6eebd80eadd8472143f2
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGF ASPM KCNAB1 PIEZO2 PLCH2 INPP5J

1.46e-041791976d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLEKHH1 SLC29A4 CDON DRD2 CADPS RXFP4

1.46e-0417919768ce5000088b727783a0619baa16a2cd036d21f54
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Acta2Rgs5.Acta2_(Mural.Acta2Rgs5.Acta2)|Cerebellum / BrainAtlas - Mouse McCarroll V32

PHEX ARTN RFX2 AOC3 MUTYH

1.46e-0411319753c745f4d975475860e793f304a846b032515b334
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Acta2Rgs5.Acta2_(Mural.Acta2Rgs5.Acta2)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

PHEX ARTN RFX2 AOC3 MUTYH

1.46e-0411319757c5317bda7f13649af4837ca717dfdad74152f8f
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

PHEX ARTN RFX2 AOC3 MUTYH

1.46e-041131975d67022ae14fae91f9f21ebe8c6ab6d8d6d725bc4
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH8 CA14 PLEKHH1 ABTB2 PIEZO2 CDH1

1.55e-041811976a8e9ea73c24109a5d4d28bc0577cc869ad932a4d
DrugCalycanthine [595-05-1]; Up 200; 11.6uM; PC3; HT_HG-U133A

HGF ACVR1B PHEX SYNJ1 MMP13 SEL1L NPHS1 ARTN RFX2 CBS LRP1

1.30e-06200195115744_UP
DiseaseCarcinoma in situ of stomach

ATR FGFR2 CDH1 MUTYH

3.64e-06171894C0154060
DiseaseBenign neoplasm of stomach

ATR FGFR2 CDH1 MUTYH

3.64e-06171894C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ATR FGFR2 CDH1 MUTYH

3.64e-06171894C0496905
DiseaseStomach Carcinoma

ATR FGFR2 CDH1 MUTYH

8.96e-06211894C0699791
Diseaseangina pectoris

CFH KCNH8 BRWD3 KCNE2 RNF213 LDLR IL6R

1.67e-051251897EFO_0003913
Diseaseretinal degeneration (biomarker_via_orthology)

CFH KCNH8 OFD1 ACVR1C

2.96e-05281894DOID:8466 (biomarker_via_orthology)
Diseasecollagenase 3 measurement

CFH MMP13

4.08e-0521892EFO_0020271
DiseaseHeadache

HGF DDX10 RNF213 LRP1 SOS1

5.74e-05641895HP_0002315
Diseasecervical cancer (is_marker_for)

BCL2L1 MMP13 SPAG5 SOS1

8.18e-05361894DOID:4362 (is_marker_for)
Diseaset-lymphocyte activation antigen CD86 measurement

CFH ST3GAL4

1.22e-0431892EFO_0020762
Diseasechromosome 15q11.2 deletion syndrome (implicated_via_orthology)

CYFIP1 CYFIP2

1.22e-0431892DOID:0060393 (implicated_via_orthology)
Diseaseendothelial growth factor measurement, hepatocyte growth factor measurement

HGF SOS1

1.22e-0431892EFO_0006900, EFO_0006903
Diseasebehavioural inhibitory control measurement

PRDM11 STRA6 TTLL11

1.36e-04161893EFO_0008467
Diseasealdose reductase measurement

CFH AKR1B1

2.43e-0441892EFO_0801364
Diseasemitogen-activated protein kinase 12 measurement

CFH MAPK12

2.43e-0441892EFO_0020576
DiseasePain, Crushing

HGF NPR1 DRD2 NTSR1

2.76e-04491894C0458259
DiseasePain, Splitting

HGF NPR1 DRD2 NTSR1

2.76e-04491894C0458257
DiseasePain

HGF NPR1 DRD2 NTSR1

2.76e-04491894C0030193
DiseasePain, Migratory

HGF NPR1 DRD2 NTSR1

2.76e-04491894C0751407
DiseaseSuffering, Physical

HGF NPR1 DRD2 NTSR1

2.76e-04491894C0751408
DiseaseRadiating pain

HGF NPR1 DRD2 NTSR1

2.76e-04491894C0234254
DiseasePain, Burning

HGF NPR1 DRD2 NTSR1

2.76e-04491894C0234230
DiseaseAche

HGF NPR1 DRD2 NTSR1

2.76e-04491894C0234238
DiseaseInfiltrating duct carcinoma of female breast

SMG1 ATR EPHA8

3.16e-04211893C3165106
Diseasesciatic neuropathy (is_implicated_in)

HGF LRP1

4.03e-0451892DOID:11446 (is_implicated_in)
Diseasethrombospondin type-1 domain-containing protein 1 measurement

CFH ST3GAL4

4.03e-0451892EFO_0802131
Diseaseautism spectrum disorder (implicated_via_orthology)

SYN3 KMT5C CNTNAP1 ARHGEF10 CTNND2 CADPS2

4.56e-041521896DOID:0060041 (implicated_via_orthology)
Diseasetriacylglycerol 56:4 measurement

SYN3 ABTB2 IPO8

4.74e-04241893EFO_0010431
DiseaseCraniofacial Abnormalities

MBTPS1 PHEX FGFR2 STRA6 MMP13 CNTN4

5.23e-041561896C0376634
Diseasefamilial atrial fibrillation

BEST3 ARNT2 SCN10A AKAP6 KCNE2 DNAH10

5.23e-041561896C3468561
DiseasePersistent atrial fibrillation

BEST3 ARNT2 SCN10A AKAP6 KCNE2 DNAH10

5.23e-041561896C2585653
DiseaseParoxysmal atrial fibrillation

BEST3 ARNT2 SCN10A AKAP6 KCNE2 DNAH10

5.23e-041561896C0235480
DiseaseAtrial Fibrillation

BEST3 ARNT2 SCN10A AKAP6 KCNE2 DNAH10

5.98e-041601896C0004238
DiseaseSchizophrenia

SYN3 ADCY7 CYFIP1 EML5 ADGRF4 FGFR2 DRD2 NTSR1 GRIK5 CBS LRP1 CTNND2 C9orf72 CADPS2 IL6R

5.99e-0488318915C0036341
DiseaseFever, response to sulfasalazine

KCNJ4 OTUD7A

6.02e-0461892EFO_0008324, HP_0001945
DiseasePorokeratosis, Disseminated Superficial Actinic

SSH1 FDPS

6.02e-0461892C0265970
Diseaseanxiety disorder (is_implicated_in)

DRD2 CTNND2

6.02e-0461892DOID:2030 (is_implicated_in)
DiseaseStomach Neoplasms

ATR BCL2L1 KISS1R FGFR2 NBAS CDH1 IL6R MUTYH

6.93e-042971898C0038356
DiseaseMalignant neoplasm of stomach

ATR BCL2L1 KISS1R FGFR2 NBAS CDH1 IL6R MUTYH

7.40e-043001898C0024623
Diseasecontactin-4 measurement

CNTN4 ST3GAL4

8.39e-0471892EFO_0020287
Diseaseatrial natriuretic factor measurement

CFH DRD2

8.39e-0471892EFO_0004789
Diseaseimmunoglobulin superfamily containing leucine-rich repeat protein 2 measurement

STRA6 ST3GAL4

8.39e-0471892EFO_0021879
DiseaseParkinsonism, Juvenile

LRRK2 SYNJ1 DRD2

9.24e-04301893C0752105
Diseasespontaneous coronary artery dissection

SYN3 KCNE2 LRP1

1.02e-03311893EFO_0010820
Diseasearteriosclerosis (is_implicated_in)

MMP13 AKR1B1 LDLR

1.02e-03311893DOID:2349 (is_implicated_in)
DiseaseVentricular Fibrillation

SCN10A KCNE2

1.11e-0381892C0042510
Diseaselymphatic vessel endothelial hyaluronic acid receptor 1 measurement

AKAP6 ST3GAL4

1.11e-0381892EFO_0020539
DiseaseSquamous cell carcinoma of lung

ATR FGFR2 ACVR1C

1.12e-03321893C0149782
DiseaseEndometrial Carcinoma

ATR FGFR2 AKR1B1 CDH1

1.19e-03721894C0476089
Diseasestomach cancer (is_implicated_in)

ACVR1B FGFR2 IL6R MUTYH

1.19e-03721894DOID:10534 (is_implicated_in)
Diseaset-cell surface glycoprotein CD5 measurement

CFH ST3GAL4

1.43e-0391892EFO_0803134
Diseaseplatelet endothelial cell adhesion molecule measurement

CFH ST3GAL4

1.43e-0391892EFO_0010598
Diseasegout

HGF ABCC8 FGFR2 MED27 SLC22A12 SOS1

1.70e-031961896EFO_0004274
DiseaseSecreted frizzled-related protein 3 measurement

CFH NCKAP1

1.78e-03101892EFO_0008277
Diseasemultimerin-2 measurement

CFH SYN3

1.78e-03101892EFO_0801809
Diseasesystolic blood pressure, self reported educational attainment

CDON CADPS

1.78e-03101892EFO_0004784, EFO_0006335
Diseasetransverse temporal cortex volume measurement

HGF SOS1

1.78e-03101892EFO_0010336
DiseaseNonsyndromic Deafness

HGF MYO7A TMEM132E KCNQ4

1.85e-03811894C3711374
DiseaseMoyamoya disease

NLN RNF213 LRP1

2.15e-03401893MONDO_0016820
Diseaseneutrophil count, mean platelet volume, leukocyte count, erythrocyte count, mean corpuscular hemoglobin concentration, mean corpuscular volume, monocyte count, obsolete_red blood cell distribution width, basophil count, platelet count, eosinophil count

FAM234A TTLL11

2.16e-03111892EFO_0004305, EFO_0004308, EFO_0004309, EFO_0004526, EFO_0004528, EFO_0004584, EFO_0004833, EFO_0004842, EFO_0005090, EFO_0005091, EFO_0005192
Diseasecolon cancer (implicated_via_orthology)

ATR CBS

2.16e-03111892DOID:219 (implicated_via_orthology)
DiseaseGASTRIC CANCER

FGFR2 MUTYH

2.16e-03111892613659
DiseasePR domain zinc finger protein 1 measurement

CFH USP4

2.16e-03111892EFO_0801904
DiseaseGastric cancer

FGFR2 MUTYH

2.16e-03111892cv:C0024623
DiseaseNeoplasm of stomach

FGFR2 MUTYH

2.16e-03111892cv:C0038356
Diseasespontaneous preterm birth, parental genotype effect measurement

HGF SOS1

2.16e-03111892EFO_0005939, EFO_0006917
DiseaseHyperhomocysteinemia

NPHS1 CBS

2.16e-03111892C0598608
DiseaseAdenocarcinoma of lung (disorder)

ATR KCNJ4 FGFR2 SOS1 EPHA8 HELLS

2.19e-032061896C0152013
DiseaseParkinson Disease

HGF LRRK2 KCNJ4 DRD2

2.20e-03851894C0030567
Diseasestomach cancer (is_marker_for)

BCL2L1 ACVR1B ASPM FGFR2 AKR1B1

2.26e-031421895DOID:10534 (is_marker_for)
Diseasehigh grade glioma (is_marker_for)

HGF ASPM HELLS

2.47e-03421893DOID:3070 (is_marker_for)
Diseaseinterferon alpha measurement

PNP DRD2

2.58e-03121892EFO_0006517
Diseasestomach carcinoma (is_implicated_in)

FGFR2 MUTYH

2.58e-03121892DOID:5517 (is_implicated_in)
Diseasehepatocyte growth factor measurement

HGF OTUD7A SOS1

2.82e-03441893EFO_0006903
DiseaseHereditary Diffuse Gastric Cancer

BCL2L1 KISS1R FGFR2 NBAS CDH1 IL6R MUTYH

2.92e-032931897C1708349
DiseaseMalignant neoplasm of salivary gland

ASPM ST3GAL4 CDH1

3.01e-03451893C0220636
Diseasevisceral:gluteofemoral adipose tissue ratio measurement

KCNE2 DNAH10 ACVR1C

3.01e-03451893EFO_0803319
Diseasetumor necrosis factor ligand superfamily member 8 measurement

CFH ST3GAL4

3.04e-03131892EFO_0010592
DiseaseSalivary Gland Neoplasms

ASPM ST3GAL4 CDH1

3.41e-03471893C0036095
Diseasemetabolite measurement

GPAA1 SYN3 MAPK12 FDPS PNP REV3L SLC22A12 BCO1 NBAS DPY19L2P2

3.43e-0356018910EFO_0004725
DiseaseParkinson's disease (implicated_via_orthology)

YIF1A SYNJ1 FOXO4 DRD2 RTCB

3.48e-031571895DOID:14330 (implicated_via_orthology)
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

CFH NPHS1

3.53e-03141892DOID:10976 (biomarker_via_orthology)
Diseasediabetic neuropathy (is_implicated_in)

HGF AKR1B1

3.53e-03141892DOID:9743 (is_implicated_in)
DiseaseAlzheimer disease, APOE carrier status

TPCN2 NTSR1 NBAS CTNND2

3.69e-03981894EFO_0007659, MONDO_0004975
Diseasecomplement factor H-related protein 4 measurement

CFH ASPM RFX2

3.84e-03491893EFO_0600091
DiseaseDown syndrome (implicated_via_orthology)

SYNJ1 CBS

4.06e-03151892DOID:14250 (implicated_via_orthology)
Diseaseinterferon gamma measurement

CFH IBTK EPHA8

4.30e-03511893EFO_0008165
Diseasedepressive disorder (biomarker_via_orthology)

BCL2L1 DRD2 IL6R

4.54e-03521893DOID:1596 (biomarker_via_orthology)
Diseasecorpus callosum posterior volume measurement

HGF XKR6 SOS1

4.54e-03521893EFO_0010298
DiseaseRomano-Ward Syndrome

SCN10A KCNE2

4.62e-03161892C0035828
Diseasecathepsin L1 measurement

LRRK2 C9orf72

4.62e-03161892EFO_0010619
Diseaseidiopathic scoliosis (implicated_via_orthology)

MBTPS1 DNAH10

4.62e-03161892DOID:0060250 (implicated_via_orthology)
Diseaseparental longevity

ADGRB2 ABCC8 PHIP RFX3 LDLR MST1R OTUD7A CDH1 IL6R

4.76e-034941899EFO_0007796
Diseaseapolipoprotein A 1 measurement, apolipoprotein B measurement

CFH DNAH10 ST3GAL4 LDLR

5.04e-031071894EFO_0004614, EFO_0004615
Diseaseinterleukin-1 beta measurement

CFH IL36B BCO1

5.05e-03541893EFO_0004812
Diseasebody mass index, osteoarthritis

DRD2 XKR6 CADPS2

5.05e-03541893EFO_0004340, MONDO_0005178
Diseaseprostate carcinoma

HGF BCL2L1 SESN1 MAGEF1 DDX10 FGFR2 AKR1B1 PHIP TPCN2 RNF213 RFX3 KDM2A SOS1

5.06e-0389118913EFO_0001663
Diseaseaortic measurement

CFH ABCC8 KCNE2 LRP1 HAS2 HELLS

5.73e-032511896EFO_0020865
DiseaseMalignant neoplasm of endometrium

ATR FGFR2

5.84e-03181892C0007103
DiseaseCarcinoma in situ of endometrium

ATR FGFR2

5.84e-03181892C0346191

Protein segments in the cluster

PeptideGeneStartEntry
AIETARAWTRLYAMN

UBE2N

136

P61088
QAIETARAWTRLYAM

UBE2NL

136

Q5JXB2
DLQSLMTEMNRYRSW

BEST3

206

Q8N1M1
TEAWQSYLAVIGRMR

ADGRB2

1016

O60241
PASQRMWRIDYSAAV

FAM234A

76

Q9H0X4
SFQRRWITRAMYQEC

ACTL10

221

Q5JWF8
SRVMSSQRYLLKWSV

ARHGEF10

686

O15013
GTWMRYNLQSALRSA

CNTNAP1

1006

P78357
MVRFWSEYFTTDRSL

AADAC

246

P22760
ERSWFREAEIYQTVM

ACVR1B

241

P36896
ITYAMSRVAWEALRR

AZIN2

406

Q96A70
QFTVNMTAAVRTYRW

DPF1

306

Q92782
TSEQYDSLLRQMWER

GTPBP1

71

O00178
VWSRVVVTEISYMRH

ADGRF4

426

Q8IZF3
SWFREAEIYQTVMLR

ACVR1C

231

Q8NER5
YRTWIESLSRCAMNN

CFAP46

706

Q8IYW2
IWMLTVLASADASRY

CNTN4

746

Q8IWV2
VLVSRIAAWMATYLN

BCL2L1

161

Q07817
VTMVAWDRYDTTVIT

BRWD3

426

Q6RI45
ENRFYRRISALMWEV

BRWD3

1196

Q6RI45
YVDSPALTNIWMART

C22orf31

31

O95567
REIMENYNIALRWTA

CFH

1171

P08603
SVRMTRYLESWGAAR

ADCY7

481

P51828
NESITLDWMFRYSLT

NPR1

626

P16066
ATRLRSRWLTYFMAV

DHX30

1066

Q7L2E3
QVLNSMWQYRDLRSL

CTNND2

1011

Q9UQB3
RAACVIQSYWRMRQD

ASPM

1561

Q8IZT6
MTTLLSYNRNWRVCA

AKR1B1

286

P15121
MARGFSWERYQLAVT

AOC3

621

Q16853
VLSVMYRFRTKNREW

ARNT2

396

Q9HBZ2
LTYIRNTKRTAEVWM

GALNT16

361

Q8N428
VMLSSVLEWYRHRAL

MROH7

726

Q68CQ1
QYTNRRAFTMLGVVW

QRFPR

156

Q96P65
MAVLLYNRWAIRTIV

INTS8

141

Q75QN2
DAVEVSTWRRCYTMQ

INTS9

171

Q9NV88
STWRRCYTMQEVNSA

INTS9

176

Q9NV88
ARMVASRITNYPTAW

OFD1

601

O75665
RYMADIFTTCVDTRW

KCNJ4

41

P48050
TAIWRLYGRSTMALQ

ANAPC5

426

Q9UJX4
DRILWVQAMYRATGQ

CADPS

611

Q9ULU8
VMLYTWRSCSRAIPQ

CYFIP1

81

Q7L576
RTVDSETWYFMVNVT

FGFR2

111

P21802
RTVSMLEYFINRSWE

FAR2

386

Q96K12
KNAMAERWESRIYAS

MISP

661

Q8IVT2
LMWYKDSRTVTESRL

NPHS1

476

O60500
MNELWRATGEVRYQT

RENBP

141

P51606
KARMSWDRESTEIRY

HELLS

51

Q9NRZ9
ASVEMYDLRRDRWTA

KLHL34

441

Q8N239
WTNMAISSVAEFRRT

MDN1

3116

Q9NU22
GITLLRSYMQSVWTE

KCNMB2

66

Q9Y691
SWIAISRYATLMQKD

GPR82

111

Q96P67
IRSLLDVAMWDYSSN

MAEL

266

Q96JY0
LIYMRGNSAREAQVW

MAGEF1

176

Q9HAY2
VIFSDWYNTSVMRKV

MBTPS1

721

Q14703
WLERTMRSVGLEVYT

GPAA1

91

O43292
VRRLMFCYISDEQWT

NTSR1

321

P30989
SIMYSTRKRSAQLWL

KMT5C

161

Q86Y97
TVLWTREAVYTMGLN

IBTK

296

Q9P2D0
IMDSSLTRRGQICWY

FDPS

171

P14324
RWSAMEIMEAYSVAR

KCNAB1

241

Q14722
IYWTDVTTQGSMIRR

LRP1

3071

Q07954
TRYEAVSFMDVNSTW

ARTN

191

Q5T4W7
VSFMDVNSTWRTVDR

ARTN

196

Q5T4W7
DYSILMNVSWVLRAD

IL17RB

61

Q9NRM6
SRYTDEEWSQTLMTV

KDM8

241

Q8N371
IQAAWRLYSTDMSRA

KCNQ4

346

P56696
VWQLMRRYTLNVLSD

PLS1

496

Q14651
RLTLAQIYEWMVRTV

FOXO4

121

P98177
EYSIWSNRIVRVMPA

MMP13

451

P45452
GMLWEARASQIRYSV

PCDHGA9

21

Q9Y5G4
MSRVALESLYRLLWV

FRYL

351

O94915
LMSRYVESWRVGDTA

CYB5RL

151

Q6IPT4
EAAMLWLEYNTESRS

KBTBD2

196

Q8IY47
RYSVSERRWTQMLAG

MEGF8

1541

Q7Z7M0
ATLTAMSVDRWYVTV

KISS1R

131

Q969F8
YMRVASVQQVGWSLL

LRRK2

71

Q5S007
RRIFITYMDNWRQNT

KCNE2

16

Q9Y6J6
TRTNIGWMVSLRYRN

HGF

501

P14210
SYMNVTWIRIPSETR

OTUD7A

436

Q8TE49
VYSSWVTDNILAMAR

PTPDC1

81

A2A3K4
VVVRSFMTWLRSYIK

MED27

261

Q6P2C8
VMLYTWRSCSRAIPQ

CYFIP2

81

Q96F07
YLVSTTVDRMSHVLW

MROH1

471

Q8NDA8
QWTETRIYMTNLAVA

GPR35

51

Q9HC97
QRYSVSRWEVFMTHL

NBAS

1691

A2RRP1
VTRAYTDELWNMALS

EXOC6

356

Q8TAG9
MRLDWFRLQAYTSVS

NCKAP1

486

Q9Y2A7
ITAAYVEMRREAWAS

MCM7

581

P33993
ANAVTLWMLFFRTRS

F2RL2

111

O00254
RYNIIMNSSTFIWVI

OR9A1P

131

Q8NGU1
LAIDHIRRTMYWTDS

NID2

1191

Q14112
ARYVWNRTELMQASL

ALPP

266

P05187
GTMVRWLRAYESAVS

PORCN

236

Q9H237
LNWVARLEMTQNSYR

ATR

1881

Q13535
TRMEFQTWALYVANR

HENMT1

186

Q5T8I9
SYAIRDSRQMVWVLS

IL36B

11

Q9NZH7
RYRAERSKTFTTWMV

IL6R

256

P08887
AYDTRTDRWHVVASM

KLHL17

361

Q6TDP4
EVWMSVFRYLSRREL

KDM2A

896

Q9Y2K7
ERPYWNMTNRDVISS

EPHA8

836

P29322
VEYKRMRTSNWLVAA

CDON

756

Q4KMG0
DSRLWQYLLSRSMRE

COMTD1

51

Q86VU5
SSVRYWMAFNIERAC

HAS2

256

Q92819
DSVRNYMTKFLSDRW

CBS

376

P35520
QDRILWVQAMYRATG

CADPS2

576

Q86UW7
ATNEWIYVADMSTRR

KLHL3

466

Q9UH77
TDFNWYTRRAMLAAI

COQ9

236

O75208
VRRRWEVMSKVYAVA

FAM172BP

246

A6NC97
VTNVRWTYDDSMLVT

EML5

1241

Q05BV3
WQVERESISRLMQNY

DDX10

46

Q13206
YSSKRRVTVMISIVW

DRD2

146

P14416
GQAFTIMLVYVWSRR

DERL2

121

Q9GZP9
REIGVWYSNRTLAMN

GRIK5

386

Q16478
LWTVFYRRSQISMEQ

CA14

226

Q9ULX7
RRFSQYMLWVTESEP

DNAH10

4306

Q8IVF4
GRRLVLTWSYLQMAV

SLC22A12

171

Q96S37
QRYSLTQWVDRNMRS

S100PBP

381

Q96BU1
AASATMRAQWTYSLR

GML

16

Q99445
YDRTMRQRALSTWKQ

PNP

166

P00491
FMEQKITYRIWRDTA

CDH1

516

P12830
YMRSELTAFWRATSE

C9orf72

331

Q96LT7
MADSRRVIIASWYRT

DPY19L2P2

1

Q6ZN68
ITVQSRDAAWYQLLM

IPO8

966

O15397
RTTWVYSINNVLMSL

MAP4K1

541

Q92918
FWLTRVTAQATVLMY

RNF139

241

Q8WU17
IWMLSNNRRVAYARI

FER1L6

721

Q2WGJ9
YAWVNRSSMTFLTRQ

RTCB

316

Q9Y3I0
LITALSVARYWVVAM

RXFP4

131

Q8TDU9
LDRYERNTTWNFSMS

TAS2R13

156

Q9NYV9
VAMTERYRLWVDSCS

SYN3

326

O14994
VDLVTYITRFQWDMA

ATP6V1C1

96

P21283
ETMAVSWAYGARRFL

SLC6A16

581

Q9GZN6
VDTSMLRRAIWNYIH

SESN1

396

Q9Y6P5
RSMQLDYTTWTALLS

SPAG5

646

Q96R06
TSQSVKRRIMWHIDY

TMEM132E

401

Q6IEE7
QLVTRFQEVFRSMWS

SYNJ1

416

O43426
ERGRWSERLMTAYNS

SEL1L

551

Q9UBV2
WSFYSSMVIRDLTLR

RFX2

616

P48378
WSFYSSMVIRDLTLR

RFX3

601

P48380
AVYVWIVRSSLQAVM

PKDREJ

326

Q9NTG1
RIVLLMHRWYLSSTE

RASGRP3

36

Q8IV61
SSIPSYDWMRRVTQR

RASGRP3

121

Q8IV61
RWKLSSAETYSRMRL

NBEAL2

1826

Q6ZNJ1
DETKANWMRYVVISR

PRDM11

211

Q9NQV5
WRVTQSYARSTAVMS

SMG1

2311

Q96Q15
VTYFINWIDEIMRLT

PRSS47P

311

A8MTI9
YEDYRWAVSSVMTRQ

SETD3

241

Q86TU7
VLVVMVWYSISREDR

ST3GAL4

16

Q11206
YWMALRNRVSAVDEL

SHPRH

1341

Q149N8
QARSWMEIIYLSEVL

CCT8L2

316

Q96SF2
DRRAYAVWVSEVMLQ

MUTYH

121

Q9UIF7
QSDRWSLMRGIYSSS

TEFM

196

Q96QE5
RAIVMRYSAEWKSTV

IARS1

121

P41252
FVDILTNWYVRMNRR

IARS1

726

P41252
YDSISRLDQWLTTML

NAPA

266

P54920
NWMAALISLQYRSTL

SOS1

536

Q07889
RRTLMAAMAWTVYEE

SLC25A38

281

Q96DW6
AMVATWRVLLSALYN

STRA6

526

Q9BX79
SWFREAEIYQTVMLR

TGFBR1

241

P36897
RLESAWADRVRYMVV

SSH1

96

Q8WYL5
WMRVAITYAEHRRSL

ABTB2

426

Q8N961
TAANRWLEVRMEYIG

ABCC8

1241

Q09428
WLRMTSERVRDLTYS

AKAP6

76

Q13023
ATAYIRRMSWASCLA

BCO1

261

Q9HAY6
AMSSYTVAGRNVLRW

NLN

36

Q9BYT8
VVRYRMETVFARSSW

INPP5J

756

Q15735
QRCMDTRTYTWLGAL

RNF213

681

Q63HN8
TVLDAIYEVSRAWNM

TIGD2

361

Q4W5G0
YIDITRRWNSMTLDQ

TTLL11

686

Q8NHH1
SMSYRGAIIQVFWRL

XKR6

351

Q5GH73
STLAMDWDSETRRLY

USP4

736

Q13107
WTSSALMYFIVRSLR

YIF1A

236

O95070
MLETVTRWHSDRATY

THOC2

1046

Q8NI27
ASVLVDSRYQQWMER

ELAC2

346

Q9BQ52
VSSLMWEVRYIEHNT

PHIP

1221

Q8WWQ0
LWRIMRNEVALTNYT

REV3L

2466

O60673
NSSSTLFTMDIWRRL

SLC5A10

386

A0PJK1
RLMTQDSWERLYQQT

SCN10A

351

Q9Y5Y9
EVARTWVTGLRYLMA

PLCH2

141

O75038
FIMYATIRTESIRWL

TXNDC15

336

Q96J42
SRRFWMMAIVYTEVA

PIEZO2

1961

Q9H5I5
VFSASYDRSLRVWSM

TRAF7

616

Q6Q0C0
TIANYLVWRMVYSRI

PHEX

361

P78562
YQPRRSTVTWDTALM

PRRT4

146

C9JH25
NISEITYSWRRETTM

SLAMF8

156

Q9P0V8
ISVLAVSAWMRDYLN

TSPAN12

26

O95859
VSAWMRDYLNNVLTL

TSPAN12

31

O95859
IQMIIRDFVLSWYRS

SNX19

106

Q92543
WESRIYAVATSGMRL

PLEKHH1

421

Q9ULM0
VRPMFTYNWTEETLR

ATP6V0A1

481

Q93050
VLRMYRWQISSFEEQ

USP30

146

Q70CQ3
RYVVARVIWADMLSI

SLC29A4

346

Q7RTT9
RVIWADMLSIAVTYF

SLC29A4

351

Q7RTT9
IYDVSTYMRTRSWLI

SLC9C2

556

Q5TAH2
SMISLYGQFRVVSWI

YIPF4

126

Q9BSR8
QLLTRFSAYMVAWVV

TMC5

611

Q6UXY8
VKWMALESLQTYRFT

MST1R

1251

Q04912
SINHRVDASSMWLYR

TPCN2

61

Q8NHX9
MYRSRWESSNKALLE

TXLNA

431

P40222
TLERWYAITFAMRLD

TSHR

516

P16473
ATTNEWTYIAEMSTR

KLHL2

471

O95198
FGNVTAIIQRMYSRW

KCNH8

466

Q96L42
VASNRIYWSDLSQRM

LDLR

436

P01130
RQADSEMTGYVVTRW

MAPK12

176

P53778
RLWAVLTVQAYARGM

MYO7A

836

Q13402