Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	RNA N6-methyladenosine methyltransferase complex	RBM15 ZC3H13 RBM15B	5.74e-06	9	87	3	GO:0036396
GeneOntologyCellularComponent	ciliary inversin compartment	ANKS6 INVS	1.02e-04	4	87	2	GO:0097543
Domain	Transcription_factor_COE	EBF2 EBF3 EBF1	3.76e-07	4	86	3	IPR003523
Domain	COE_HLH	EBF2 EBF3 EBF1	3.76e-07	4	86	3	IPR032201
Domain	COE_DBD	EBF2 EBF3 EBF1	3.76e-07	4	86	3	IPR032200
Domain	Transcription_factor_COE_CS	EBF2 EBF3 EBF1	3.76e-07	4	86	3	IPR018350
Domain	COE1_HLH	EBF2 EBF3 EBF1	3.76e-07	4	86	3	PF16423
Domain	COE1_DBD	EBF2 EBF3 EBF1	3.76e-07	4	86	3	PF16422
Domain	COE	EBF2 EBF3 EBF1	3.76e-07	4	86	3	PS01345
Domain	SPOC_met	RBM15 RBM15B	6.27e-05	3	86	2	IPR010912
Domain	SPOC	RBM15 RBM15B	1.25e-04	4	86	2	PS50917
Domain	-	RBM15 RBM15B	2.08e-04	5	86	2	2.40.290.10
Domain	SPOC-like_C_dom	RBM15 RBM15B	2.08e-04	5	86	2	IPR016194
Domain	IPT	EBF2 EBF3 EBF1	2.55e-04	27	86	3	SM00429
Domain	Znf_C2HC	KAT7 MYT1	3.11e-04	6	86	2	IPR002515
Domain	zf-C2HC	KAT7 MYT1	3.11e-04	6	86	2	PF01530
Domain	SPOC_C	RBM15 RBM15B	3.11e-04	6	86	2	IPR012921
Domain	SPOC	RBM15 RBM15B	3.11e-04	6	86	2	PF07744
Domain	TIG	EBF2 EBF3 EBF1	3.86e-04	31	86	3	PF01833
Domain	IPT	EBF2 EBF3 EBF1	4.25e-04	32	86	3	IPR002909
Domain	ZF_CCHHC	KAT7 MYT1	4.34e-04	7	86	2	PS51802
Domain	Ig_E-set	EBF2 EBF3 PRKAB2 EBF1	1.36e-03	104	86	4	IPR014756
Domain	HLH	EBF2 EBF3 EBF1 MGA	2.03e-03	116	86	4	SM00353
Domain	RRM_1	HNRNPDL RBM15 RBM12 RBM15B ZNF638	2.74e-03	208	86	5	PF00076
Domain	Ank_2	ANKS6 ASB16 CASKIN1 ANKRD52 INVS	3.16e-03	215	86	5	PF12796
Domain	RRM	HNRNPDL RBM15 RBM12 RBM15B ZNF638	3.29e-03	217	86	5	SM00360
Domain	SAM_1	ANKS6 CASKIN1 PHC2	3.81e-03	68	86	3	PF00536
Domain	Znf_RING	MARCHF10 RNF19B RNF135 PHRF1 RNFT1 DCST1	3.94e-03	326	86	6	IPR001841
Domain	RRM_dom	HNRNPDL RBM15 RBM12 RBM15B ZNF638	3.98e-03	227	86	5	IPR000504
Domain	Ank	ANKS6 ASB16 CASKIN1 ANKRD52 INVS	4.05e-03	228	86	5	PF00023
Domain	-	MAMSTR PIAS1	4.16e-03	21	86	2	1.10.720.30
Domain	RRM	HNRNPDL RBM15 RBM12 RBM15B ZNF638	4.21e-03	230	86	5	PS50102
Domain	SAP	MAMSTR PIAS1	4.56e-03	22	86	2	PF02037
Domain	SAP	MAMSTR PIAS1	4.98e-03	23	86	2	SM00513
Domain	-	HNRNPDL RBM15 RBM12 RBM15B ZNF638	5.39e-03	244	86	5	3.30.70.330
Domain	-	ANKS6 ASB16 CASKIN1 ANKRD52 INVS	5.77e-03	248	86	5	1.25.40.20
Domain	SAP	MAMSTR PIAS1	5.87e-03	25	86	2	PS50800
Domain	SAP_dom	MAMSTR PIAS1	5.87e-03	25	86	2	IPR003034
Domain	ANK	ANKS6 ASB16 CASKIN1 ANKRD52 INVS	6.06e-03	251	86	5	SM00248
Domain	ANK_REPEAT	ANKS6 ASB16 CASKIN1 ANKRD52 INVS	6.27e-03	253	86	5	PS50088
Domain	Ankyrin_rpt-contain_dom	ANKS6 ASB16 CASKIN1 ANKRD52 INVS	6.37e-03	254	86	5	IPR020683
Domain	ANK_REP_REGION	ANKS6 ASB16 CASKIN1 ANKRD52 INVS	6.37e-03	254	86	5	PS50297
Domain	Nucleotide-bd_a/b_plait	HNRNPDL RBM15 RBM12 RBM15B ZNF638	6.79e-03	258	86	5	IPR012677
Domain	Ankyrin_rpt	ANKS6 ASB16 CASKIN1 ANKRD52 INVS	7.24e-03	262	86	5	IPR002110
Domain	SAM	ANKS6 CASKIN1 PHC2	7.81e-03	88	86	3	SM00454
Domain	ZnF_U1	ZNF638 ZFHX3	7.85e-03	29	86	2	SM00451
Domain	Znf_U1	ZNF638 ZFHX3	7.85e-03	29	86	2	IPR003604
Domain	Znf_C3HC4_RING-type	MARCHF10 RNF135 PHRF1 RNFT1	8.21e-03	172	86	4	IPR018957
Pubmed	The characterization of the Olf-1/EBF-like HLH transcription factor family: implications in olfactory gene regulation and neuronal development.	EBF2 EBF3 EBF1	1.51e-08	3	87	3	9151732
Pubmed	Cloning and functional characterization of Roaz, a zinc finger protein that interacts with O/E-1 to regulate gene expression: implications for olfactory neuronal development.	EBF2 EBF3 EBF1	6.04e-08	4	87	3	9151733
Pubmed	Cloning of a novel Olf-1/EBF-like gene, O/E-4, by degenerate oligo-based direct selection.	EBF2 EBF3 EBF1	6.04e-08	4	87	3	12139918
Pubmed	Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling.	CACNA1B EBF3 ZFHX3 EBF1	6.50e-08	16	87	4	17444492
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	KAT7 NCOR1 KRBA1 EBF3 ZC3H13 MYT1 ZNF638 ZFHX3 EBF1 MGA DCUN1D3 PIAS1 ZNF445	1.10e-07	808	87	13	20412781
Pubmed	Formation of whisker-related principal sensory nucleus-based lemniscal pathway requires a paired homeodomain transcription factor, Drg11.	EBF2 EBF3 EBF1	1.51e-07	5	87	3	12917357
Pubmed	Expression patterns of the coe/ebf transcription factor genes during chicken and mouse limb development.	EBF2 EBF3 EBF1	1.51e-07	5	87	3	15261831
Pubmed	Family of Ebf/Olf-1-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system.	EBF2 EBF3 EBF1	3.01e-07	6	87	3	9389446
Pubmed	Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.	EBF2 EBF3 EBF1	5.25e-07	7	87	3	24786561
Pubmed	Genetic disruptions of O/E2 and O/E3 genes reveal involvement in olfactory receptor neuron projection.	EBF2 EBF3 EBF1	8.39e-07	8	87	3	14993187
Pubmed	Control of hindbrain motor neuron differentiation by the homeobox gene Phox2b.	EBF2 EBF3 EBF1	2.46e-06	11	87	3	10704382
Pubmed	Transient and lineage-restricted requirement of Ebf3 for sternum ossification.	EBF2 EBF3 EBF1	3.27e-06	12	87	3	32398354
Pubmed	An ancient role for collier/Olf/Ebf (COE)-type transcription factors in axial motor neuron development.	EBF2 EBF3 EBF1	3.27e-06	12	87	3	30658714
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	HNRNPDL BICD2 NCOR1 RBM15 ESYT2 STC2 ZC3H13 PHRF1 RBM15B ZNF638 PHC2	3.72e-06	774	87	11	15302935
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	HNRNPDL KAT7 NCOR1 RBM15 ESYT2 NTHL1 ZC3H13 SURF6 PHRF1 ZNF629 RBM15B ZNF638 MGA PHC2	3.89e-06	1294	87	14	30804502
Pubmed	Control of the migratory pathway of facial branchiomotor neurones.	EBF2 EBF3 EBF1	4.25e-06	13	87	3	11076752
Pubmed	Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem.	EBF2 EBF3 EBF1	4.25e-06	13	87	3	22421355
Pubmed	Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes.	EBF2 EBF1	6.19e-06	2	87	2	32130892
Pubmed	m6Am methyltransferase PCIF1 negatively regulates ciliation by inhibiting BICD2 expression.	BICD2 PCIF1	6.19e-06	2	87	2	38526325
Pubmed	Kaposi's sarcoma-associated herpesvirus ORF57 interacts with cellular RNA export cofactors RBM15 and OTT3 to promote expression of viral ORF59.	RBM15 RBM15B	6.19e-06	2	87	2	21106733
Pubmed	Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade.	EBF2 EBF1	6.19e-06	2	87	2	17060461
Pubmed	Ebf2 is required for development of dopamine neurons in the midbrain periaqueductal gray matter of mouse.	EBF2 EBF3 EBF1	6.73e-06	15	87	3	25762221
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZFYVE28 RBM12 CASKIN1 PHRF1 OSBPL5 CRTC1 SNRK DEPDC5 IQCE	7.30e-06	529	87	9	14621295
Pubmed	The Transcription Factors EBF1 and EBF2 Are Positive Regulators of Myelination in Schwann Cells.	EBF2 EBF3 EBF1	1.00e-05	17	87	3	27889898
Pubmed	A key role for the HLH transcription factor EBF2COE2,O/E-3 in Purkinje neuron migration and cerebellar cortical topography.	EBF2 EBF3 EBF1	1.67e-05	20	87	3	16774995
Pubmed	High-resolution genetic localization of a modifying locus affecting disease severity in the juvenile cystic kidneys (jck) mouse model of polycystic kidney disease.	ANKS6 INVS	1.85e-05	3	87	2	27114383
Pubmed	Age-Progressive and Gender-Dependent Bone Phenotype in Mice Lacking Both Ebf1 and Ebf2 in Prrx1-Expressing Mesenchymal Cells.	EBF2 EBF1	1.85e-05	3	87	2	35137272
Pubmed	The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways.	EBF2 EBF3 EBF1	1.95e-05	21	87	3	27600842
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PCNX2 NCOR1 ANKS6 CASKIN1 SURF6 OSBPL5 DEPDC5 MBD5 SUFU IQCE PHC2 THAP11	1.97e-05	1105	87	12	35748872
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	PCNX2 NCOR1 STARD9 NTHL1 OSBPL5 IQCE	2.72e-05	233	87	6	37704626
Pubmed	Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors.	EBF2 EBF3 EBF1	2.95e-05	24	87	3	20826655
Pubmed	Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord.	EBF2 EBF3 EBF1	3.34e-05	25	87	3	15229182
Pubmed	The RNA-binding motif protein 15B (RBM15B/OTT3) acts as cofactor of the nuclear export receptor NXF1.	RBM15 RBM15B	3.70e-05	4	87	2	19586903
Pubmed	Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export.	RBM15 RBM15B	3.70e-05	4	87	2	16129689
Pubmed	ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.	ANKS6 INVS	3.70e-05	4	87	2	23793029
Pubmed	Sumoylation of PPARγ contributes to vascular endothelium insulin resistance through stabilizing the PPARγ-NcoR complex.	NCOR1 PIAS1	3.70e-05	4	87	2	30982983
Pubmed	An oligodendrocyte enhancer in a phylogenetically conserved intron region of the mammalian myelin gene Opalin.	MYT1 TLL2	3.70e-05	4	87	2	17442045
Pubmed	SUMOylation of the corepressor N-CoR modulates its capacity to repress transcription.	NCOR1 PIAS1	3.70e-05	4	87	2	16421255
Pubmed	Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons.	EBF2 EBF3 EBF1	4.23e-05	27	87	3	33760820
Pubmed	EBF2 determines and maintains brown adipocyte identity.	EBF2 EBF3 EBF1	5.27e-05	29	87	3	23499423
Pubmed	Multimodal Hox5 activity generates motor neuron diversity.	EBF2 EBF3 EBF1	5.27e-05	29	87	3	39289460
Pubmed	Human transcription factor protein interaction networks.	FLG NCOR1 ASXL1 RBM12 SURF6 ZNF629 ZNF638 ZFHX3 SUFU MGA PIAS1 MRPL1 THAP11	5.44e-05	1429	87	13	35140242
Pubmed	Genome-wide identification and gene expression profiling of ubiquitin ligases for endoplasmic reticulum protein degradation.	RNF19B RNFT1	6.16e-05	5	87	2	27485036
Pubmed	Co-repressor activity of scaffold attachment factor B1 requires sumoylation.	NCOR1 PIAS1	6.16e-05	5	87	2	21527249
Pubmed	Odorant receptors can mediate axonal identity and gene choice via cAMP-independent mechanisms.	EBF3 GNAS	6.16e-05	5	87	2	27466441
Pubmed	Combined analysis of exon splicing and genome wide polymorphism data predict schizophrenia risk loci.	BICD2 ZC3H13	6.16e-05	5	87	2	24507884
Pubmed	Stem cell niche-specific Ebf3 maintains the bone marrow cavity.	EBF3 EBF1	6.16e-05	5	87	2	29563184
Pubmed	m(6)A RNA methylation promotes XIST-mediated transcriptional repression.	RBM15 RBM15B	6.16e-05	5	87	2	27602518
Pubmed	Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle.	RBM15 ZC3H13	9.22e-05	6	87	2	24100041
Pubmed	Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells.	ESYT2 OSBPL5	9.22e-05	6	87	2	30220461
Pubmed	Sumoylation of peroxisome proliferator-activated receptor gamma by apoptotic cells prevents lipopolysaccharide-induced NCoR removal from kappaB binding sites mediating transrepression of proinflammatory cytokines.	NCOR1 PIAS1	9.22e-05	6	87	2	18832723
Pubmed	The transcription factor, Lmx1b, is necessary for the development of the principal trigeminal nucleus-based lemniscal pathway.	EBF3 EBF1	9.22e-05	6	87	2	20621716
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	NCOR1 PTPN6 SUFU MGA PLEKHA7 PIAS1 IQCE	1.05e-04	430	87	7	35044719
Pubmed	Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor.	NCOR1 ASXL1	1.29e-04	7	87	2	16606617
Pubmed	Expression of protein tyrosine phosphatase genes in the developing brain of mouse and rat.	PTPN6 PTPRB	1.29e-04	7	87	2	7804149
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	HNRNPDL KAT7 FLG RBM15 ZC3H13 RBM15B ZNF638 ZFHX3	1.40e-04	605	87	8	28977666
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	HNRNPDL NCOR1 ANKS6 ARL11 SURF6 ZNF638 ZFHX3 MGA IQCE	1.44e-04	777	87	9	35844135
Pubmed	Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.	EBF1 GNAS PLEKHA7	1.62e-04	42	87	3	21909110
Pubmed	TWIST1 Homodimers and Heterodimers Orchestrate Lineage-Specific Differentiation.	EBF3 EBF1	1.72e-04	8	87	2	32179550
Pubmed	A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.	NCOR1 PIAS1	1.72e-04	8	87	2	16127449
Pubmed	The Inv compartment of renal cilia is an intraciliary signal-activating center to phosphorylate ANKS6.	ANKS6 INVS	1.72e-04	8	87	2	29395339
Pubmed	Genomic analysis of mouse retinal development.	NCOR1 ADIPOR1 RP1L1 PHRF1 ZNF629 SNRK EBF1 PIAS1 TLCD2 PHC2	2.09e-04	1006	87	10	15226823
Pubmed	Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase.	ZC3H13 CENPU PHC2	2.26e-04	47	87	3	15009096
Pubmed	AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair.	PTPRB PRKAB2 ZFHX3 ANKRD52	2.48e-04	121	87	4	31900314
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	BICD2 KAT7 NCOR1 RBM15 ZC3H13 ZNF638 ANKRD52	2.74e-04	503	87	7	16964243
Pubmed	A POU domain transcription factor-dependent program regulates axon pathfinding in the vertebrate visual system.	EBF3 EBF1	2.75e-04	10	87	2	11163266
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	BICD2 NCOR1 ESYT2 RNF135 CRTC1 SUFU MGA PLEKHA7 ANKRD52	2.86e-04	853	87	9	28718761
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	NCOR1 RBM15 ESYT2 PTPN6 PTPRB ZNF638 SLC39A6 SUFU PLEKHA7 ANKRD52	2.92e-04	1049	87	10	27880917
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	BICD2 RBM12 PTPRB ZC3H13	3.56e-04	133	87	4	15144186
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	FLG RBM15 EBF3 ZC3H13 SURF6 ZNF629 RBM15B ZNF638 PHC2 THAP11	3.73e-04	1082	87	10	38697112
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	EBF3 MYT1 ZNF638 ZFHX3 EBF1 DCUN1D3 PIAS1 ZNF445	4.07e-04	709	87	8	22988430
Pubmed	Formation of the Mouse Internal Capsule and Cerebral Peduncle: A Pioneering Role for Striatonigral Axons as Revealed in Isl1 Conditional Mutants.	ZFHX3 EBF1	4.74e-04	13	87	2	35273083
Pubmed	CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.	EBF2 ADIPOR1 PRKAB2 GNAS	5.06e-04	146	87	4	29688375
Pubmed	Loss of all 3 Extended Synaptotagmins does not affect normal mouse development, viability or fertility.	ESYT2 OSBPL5	5.52e-04	14	87	2	27399837
Pubmed	Selection system for genes encoding nuclear-targeted proteins.	RBM12 THAP11	5.52e-04	14	87	2	9853615
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	KAT7 NCOR1 RBM15 ZNF638 PIAS1 PHC2	5.92e-04	411	87	6	35182466
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	HNRNPDL NCOR1 RBM15 ZC3H13 SURF6 RBM15B ZNF638 MGA MRPL1	6.42e-04	954	87	9	36373674
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	BICD2 NCOR1 CRTC1 ZFHX3 MGA ANKRD52	6.47e-04	418	87	6	34709266
Pubmed	Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.	NCOR1 ZNF638 MGA PIAS1	6.49e-04	156	87	4	37108203
Pubmed	A yeast two-hybrid screen reveals that osteopontin associates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain.	ZNF638 SLC39A6 CC2D1B	6.74e-04	68	87	3	22779921
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	BICD2 NCOR1 RBM15 ZNF629 GNAS ANKRD52 PIAS1	6.93e-04	588	87	7	38580884
Pubmed	Control of neuronal morphology by the atypical cadherin Fat3.	EBF2 EBF3	7.26e-04	16	87	2	21903076
Pubmed	The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression.	ASXL1 ZC3H13	7.26e-04	16	87	2	20805357
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	NCOR1 RBM15 PIAS1 MRPL1 PHC2	7.27e-04	282	87	5	23667531
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	NCOR1 SURF6 ZNF638 ZFHX3 MGA	7.38e-04	283	87	5	30585729
Pubmed	The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer.	EBF3 MYT1 ZFHX3	8.96e-04	75	87	3	37298722
Pubmed	Human variation in alcohol response is influenced by variation in neuronal signaling genes.	PTPRB ZNF638 ZFHX3 GNAS	9.14e-04	171	87	4	20201926
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	HNRNPDL RBM15 RBM12 ZC3H13 SURF6 RBM15B ZNF638 MRPL1	9.45e-04	807	87	8	22681889
Pubmed	The paired homeodomain protein DRG11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord.	EBF2 EBF1	1.03e-03	19	87	2	11498051
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	HNRNPDL ZC3H13 PRKAB2 OSBPL5 ZNF638 MRPL1	1.08e-03	462	87	6	31138677
Pubmed	Recruitment of the human TREX complex to mRNA during splicing.	RBM15 ZC3H13	1.14e-03	20	87	2	15998806
Pubmed	The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins.	SUFU PIAS1	1.14e-03	20	87	2	14611647
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	RBM15 ESYT2 RBM15B ZNF638 GNAS	1.16e-03	313	87	5	38270169
Pubmed	Nephronophthisis-Related Ciliopathies	ANKS6 INVS	1.26e-03	21	87	2	27336129
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	KAT7 NCOR1 RBM15 ZC3H13 SURF6 ZNF629 RBM15B ZNF638	1.29e-03	847	87	8	35850772
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KRBA1 ADAMTS9 ZNF629 CC2D1B MBD5 MGA	1.51e-03	493	87	6	15368895
Pubmed	Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.	ASXL1 EBF3 PHC2	1.52e-03	90	87	3	15033168
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	HNRNPDL KAT7 TAGAP ZC3H13 ZNF638 CRTC1 MGA PLEKHA7 ZNF445	1.57e-03	1084	87	9	11544199
Pubmed	Developmental diversification of cortical inhibitory interneurons.	MYT1 ZFHX3 EBF1	1.57e-03	91	87	3	29513653
Pubmed	Emx2 directs the development of diencephalon in cooperation with Otx2.	EBF3 EBF1	1.65e-03	24	87	2	11493561
GeneFamily	RNA binding motif containing	HNRNPDL RBM15 RBM12 RBM15B ZNF638	9.39e-04	213	64	5	725
GeneFamily	Ankyrin repeat domain containing	ANKS6 ASB16 CASKIN1 ANKRD52 INVS	1.65e-03	242	64	5	403
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 STARD9 CASKIN1 ZNF629 CRTC1 DCUN1D3 ZNF445	1.34e-07	200	87	7	36de49593cf6ff1c9229fcceb150c1d68658a360
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma-2\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CACNA1B MARCHF10 ASB16 CASKIN1 MYT1 SHISA7	4.28e-07	146	87	6	bc2adef529d0bbfcccef7435401a47a6ffcc1832
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CACNA1B MARCHF10 ASB16 CASKIN1 MYT1 SHISA7	4.28e-07	146	87	6	72c1e7e0c2b6ff6c4084af61fa19c2b8eab16eda
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ESYT2 PTPRB STC2 ADAMTS9 SNRK PHC2	1.71e-06	185	87	6	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FNDC1 ARL11 PRKAB2 OSBPL5 CENPU	1.42e-05	157	87	5	f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN6 GUCY2F RNF135 PHRF1 MRPL1	1.76e-05	164	87	5	b175258fb0885afd84d4a414c0ae441f880e8469
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-B_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN6 GUCY2F RNF135 PHRF1 MRPL1	1.76e-05	164	87	5	875d922eec7e3df0998ddf0c8c4dee2dcd5b23ca
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN6 GUCY2F RNF135 PHRF1 MRPL1	1.76e-05	164	87	5	8bcfc93220d7c99dddb32b7fa7fb9aec2a1c63fa
ToppCell	Control-Endothelial_cells-Systemic_venous_endothelial_cells\|Control / group, cell type (main and fine annotations)	PTPRB STC2 ADAMTS9 EBF3 EPB41L4A	2.21e-05	172	87	5	c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PTPRB STC2 ADAMTS9 SNRK PHC2	2.75e-05	180	87	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	COVID-19-Heart-EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EBF2 PTPRB ADAMTS9 EBF3 EBF1	2.90e-05	182	87	5	e67f3234165199085c793915ebb1f9bbd845e933
ToppCell	droplet-Fat-Scat-18m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB ADAMTS9 SNRK FAM181B DCST1	2.90e-05	182	87	5	fea094fe0e7796c084e60b5310c1559658633f7a
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PTPRB ADAMTS9 EBF3 EBF1 EPB41L4A	2.97e-05	183	87	5	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRB ADAMTS9 CASKIN1 ZNF629 FAM181B	3.21e-05	186	87	5	4ae3c0fe8640a8d029875cf3f0f5ffbba38e85f8
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	EBF2 PTPRB ADAMTS9 ZFHX3 EBF1	3.56e-05	190	87	5	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	COVID-19-Heart-Mito_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EBF2 PTPRB ADAMTS9 EBF3 EBF1	3.56e-05	190	87	5	ea74e0e38bcaba125b48c88331e9ba09228d3178
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Late_pre-B\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PTPN6 TAGAP ARL11 EBF1 FCMR	3.65e-05	191	87	5	2b05be1888cccd03a32341bcb1de4a899d4179fd
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRB STC2 ADAMTS9 FAM181B EPB41L4A	3.74e-05	192	87	5	0aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCell	human_hepatoblastoma-Endothelial_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	ZFYVE28 PTPRB ADAMTS9 EBF1 EPB41L4A	3.74e-05	192	87	5	e09f609fed033a25baacaf4a07bbbae1076da366
ToppCell	COVID-19-Endothelial_cells-Inflamed_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PTPRB STC2 ADAMTS9 SNRK EPB41L4A	3.83e-05	193	87	5	979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRB EBF3 SNRK EBF1 DCST1	3.83e-05	193	87	5	807fa1443b3c883cb318c71f4fca3c41d58f4910
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	PTPRB ADAMTS9 SNRK EBF1 PHC2	3.83e-05	193	87	5	479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRB STC2 ADAMTS9 SNRK EPB41L4A	4.02e-05	195	87	5	56efeb58df19f357d7d5ce87348d4f196a595421
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPRB ADAMTS9 EBF3 SNRK EBF1	4.12e-05	196	87	5	5609b2d93172a488b35d854298a3a4e504e17e28
ToppCell	Bronchial_Biopsy-Endothelial-Endothelial\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	PTPRB STC2 ADAMTS9 EBF3 EBF1	4.33e-05	198	87	5	d4a4e5c358d26d09ff27541ce49d0db75c1cd08e
ToppCell	Bronchial_Biopsy-Endothelial\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	PTPRB STC2 ADAMTS9 EBF3 EBF1	4.33e-05	198	87	5	ec80b05b8a1800c341b5741bf3e57213308398a7
Disease	Nephronophthisis, familial juvenile	ANKS6 ADAMTS9	1.55e-04	7	81	2	C1855681
Disease	NEPHRONOPHTHISIS 2	ANKS6 INVS	2.06e-04	8	81	2	C1865872
Disease	influenza A severity measurement	ZFYVE28 CRTC1	2.65e-04	9	81	2	EFO_0007743
Disease	cortical surface area measurement	BICD2 NCOR1 ADAMTS9 ZC3H13 MYT1 RP1L1 ZFHX3 EBF1 TTC34 SUFU PLEKHA7 PHC2	2.95e-04	1345	81	12	EFO_0010736
Disease	esophageal adenocarcinoma, Barrett's esophagus, sex interaction measurement	RP1L1 CRTC1	5.69e-04	13	81	2	EFO_0000280, EFO_0000478, EFO_0008343
Disease	Nephronophthisis	ANKS6 INVS	5.69e-04	13	81	2	C0687120
Disease	body weight	EBF2 CACNA1B NCOR1 ZNF638 CRTC1 ZFHX3 EBF1 GNAS MGA CDK10 PHC2	6.49e-04	1261	81	11	EFO_0004338
Disease	cryptococcosis	PIAS1 JMY	7.64e-04	15	81	2	EFO_0007229
Disease	S-adenosylhomocysteine measurement	CACNA1B CRTC1	9.85e-04	17	81	2	EFO_0010531
Disease	CCL11 measurement	SNRK EBF1	1.81e-03	23	81	2	EFO_0005188
Disease	low density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram	ZFHX3 TTC34	1.98e-03	24	81	2	EFO_0004611, EFO_0006329, EFO_0007871
Disease	Varicose veins	RP1L1 MAMSTR EBF1 GNAS	1.99e-03	193	81	4	HP_0002619
Disease	mean arterial pressure, alcohol drinking	RP1L1 EBF1 PLEKHA7	2.51e-03	98	81	3	EFO_0004329, EFO_0006340
Disease	triglyceride measurement, alcohol drinking	PCIF1 MAMSTR EBF1	2.59e-03	99	81	3	EFO_0004329, EFO_0004530
Disease	triglyceride measurement, alcohol consumption measurement	PCIF1 MAMSTR EBF1	2.74e-03	101	81	3	EFO_0004530, EFO_0007878

Protein segments in the cluster

Peptide	Gene	Start	Entry
HAPGSRLGARRRAKT	ESYT2	51	A0FGR8
LDHEQTRRGRAKAAP	BICD2	801	Q8TD16
DARAAGRKRHTPLHN	ASB16	276	Q96NS5
PHRSEGARRSKNTLE	CENPU	11	Q71F23
NSKHGRRARRLDPSE	EBF2	236	Q9HAK2
SDRVSGERHGAKAAR	PRKAB2	6	O43741
HSGIPRRQASSAVRD	FLG	1046	P20930
VNSRDAKGRTPLHAA	ANKRD52	851	Q8NB46
SGEEPARRHRARHKA	CACNA1B	971	Q00975
DREPSNKSHSRRGAG	DCUN1D3	21	Q8IWE4
TRQRDGHFKKRSRPD	ASXL1	401	Q8IXJ9
GQKRSRSRSPHEAGF	RBM12	416	Q9NTZ6
RGSDRTPERSRKENH	RBM15B	626	Q8NDT2
NFRRPEDARAAKHAR	RBM15	221	Q96T37
NRTRASDRHGIPAQK	QRICH2	966	Q9H0J4
SALHRQPRGDRNKDH	IQCE	376	Q6IPM2
APSSARQGARRAQRH	HNRNPDL	46	O14979
HAAPQATREKIRSRF	ZFYVE28	706	Q9HCC9
LQARAHGAERGDSKR	ARL11	181	Q969Q4
GPENAAAVTHAQRRR	OTOA	1076	Q7RTW8
KLHNRSAPRDSRLGD	DEPDC5	381	O75140
RSHSVRAPAGADKNV	CASKIN1	916	Q8WXD9
DRGARGAAKLLSHSR	TCTE1	321	Q5JU00
ICRQKVSHGRERPSA	PTPRB	1641	P23467
DRFATPKHRQTRAGV	ADIPOR1	256	Q96A54
DSGSDLSHRPKRRRF	KAT7	161	O95251
HSPSRRKSHRGQERG	KRBA1	181	A5PL33
LRLAHARRKGAASPV	JMY	701	Q8N9B5
VPRRAAKSSRGNGHF	MGA	2256	Q8IWI9
GRRKGRSQSVQAHSA	PCNX2	1931	A6NKB5
HRDGSLSAKRAAPVS	PHRF1	526	Q9P1Y6
QTRSHSPERKGAVRE	PHRF1	1186	Q9P1Y6
AHGKAAPRREASQAA	FAM181B	141	A6NEQ2
GSPDAAAAVRKDRLH	ADAMTS9	21	Q9P2N4
LRRQCGPHVSAAAKD	PCIF1	341	Q9H4Z3
HRNKRAAPATSEGQS	CDK10	341	Q15131
RRPLSVDKHGRQADS	CRTC1	116	Q6UUV9
GREARQAPASRLHLS	DCST1	221	Q5T197
RATNRRGLGPHSKAF	FNDC1	436	Q4ZHG4
LPKRNGSRHAAEIAN	GUCY2F	941	P51841
RAHRAGRKVNFAELP	CC2D1B	426	Q5T0F9
SSDRSRTRHNGKADP	ANKS6	571	Q68DC2
NNSKHGRRARRLDPS	EBF1	236	Q9UH73
ESHSPRASGDRSRQK	MARCHF10	151	Q8NA82
ARRQGSVKPSAASHR	MAMSTR	236	Q6ZN01
RAATPRSVRNKSHEG	MBD5	141	Q9P267
SSSLNPGVARGHRDR	CXCL17	21	Q6UXB2
NNSKHGRRARRLDPS	EBF3	236	Q9H4W6
DSVQPVRRRKAHNSG	EPB41L4A	451	Q9HCS5
QELKRRRGPASSHCQ	nan	406	A6NNC1
RRPNETAREHSKGQS	INVS	686	Q9Y283
RHERSGPDQRLRKAS	OSBPL5	751	Q9H0X9
EKQHARAAPSRGTAR	NUTM2D	556	Q5VT03
RRAAREIQAGSDPAH	RNF135	86	Q8IUD6
ASARGRRARAKPQAE	RNF19B	41	Q6ZMZ0
LQSRAAQRHRGSAKD	PLEKHN1	526	Q494U1
SQDFTRDHVPRGVRK	TAGAP	531	Q8N103
RREAAAEARKSHSPV	NTHL1	41	P78549
RRAASAAPASGARRK	GNAS	511	Q5JWF2
KNAREGTRSPRTAHE	NCOR1	1226	O75376
DSPRRARGHAVKNSS	PLEKHA7	611	Q6IQ23
AFSKASRAPRAHRDI	SHISA7	206	A6NL88
HSAPEQQARTRAGKT	SURF6	21	O75683
FSHAAPAQDRKRRTG	STARD9	2666	Q9P2P6
RHRSQRLGNSFVPEK	STARD9	4021	Q9P2P6
RLRAKGIRNPDHSRA	PIAS1	296	O75925
PARAADSVLNGHRSK	SNRK	391	Q9NRH2
AHRPEHASGRRNVKD	SLC39A6	166	Q13433
AQKHRGPATLAEACR	STRA8	201	Q7Z7C7
SAGRRDVRAKAHITA	TAS2R5	206	Q9NYW4
IRVPNRHFAAATKSA	MRPL1	36	Q9BYD6
GAATHNRRRASKASL	PHC2	691	Q8IXK0
GHERRQRPEAKTSGS	RNFT1	16	Q5M7Z0
PGHEKTRGTRTRRDN	TLCD2	236	A6NGC4
PLHASQGERVAARKR	RP1L1	411	Q8IWN7
ERGSKSHPNAHARGR	STC2	261	O76061
HRPRVSRASSVAGDK	FCMR	186	O60667
RQNGLAHDRAPSRKD	SUFU	331	Q9UMX1
LHAAAKTFSPRVRRA	TLL2	136	Q9Y6L7
PCHRDRNTKGNSSRV	UBQLNL	121	Q8IYU4
EVQPTHCGQDSRRRK	nan	136	Q6ZUG5
RGVHGSFLARPSRKN	PTPN6	21	P29350
RKHTRAAQAERSPPA	ZNF445	916	P59923
HERGKTPARRAQGDS	ZNF629	536	Q9UEG4
KALHRAPTSEAARAR	TTC34	331	A8MYJ7
NERKVARRPAGAAAA	THAP11	86	Q96EK4
GKAFNDPSALRSHAR	ZNF317	256	Q96PQ6
GNRKENETPRRRSHS	ZNF638	476	Q14966
RSGDDQSGRKRVLHS	ZC3H13	1216	Q5T200
RTITRAARNAKEHPS	ZFHX3	3556	Q15911
HRSASGCPLAARRQK	MYT1	911	Q01538