Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	E-box binding	TCF3 TCF12 PTF1A TFAP4 TFE3 ASCL1 MITF	9.92e-08	61	124	7	GO:0070888
GeneOntologyMolecularFunction	molecular adaptor activity	ANKRD13B ATG16L1 RIPK1 OFD1 PPRC1 IKBKG ABT1 EMILIN1 NLRP6 SPTBN4 TCHH G3BP1 MYH14 HGS GIGYF2 TRAF3IP3 TNNT2 GCN1 PBXIP1 ZNF433 CUX1	8.87e-05	1356	124	21	GO:0060090
GeneOntologyMolecularFunction	integrin binding involved in cell-matrix adhesion	EMILIN1 SVEP1	3.78e-04	5	124	2	GO:0098640
Domain	-	MYCN TFEB TCF3 TCF12 PTF1A TFAP4 TFE3 ASCL1 MITF	3.19e-08	109	119	9	4.10.280.10
Domain	HLH	MYCN TFEB TCF3 TCF12 PTF1A TFAP4 TFE3 ASCL1 MITF	3.74e-08	111	119	9	PF00010
Domain	HLH	MYCN TFEB TCF3 TCF12 PTF1A TFAP4 TFE3 ASCL1 MITF	5.49e-08	116	119	9	SM00353
Domain	BHLH	MYCN TFEB TCF3 TCF12 PTF1A TFAP4 TFE3 ASCL1 MITF	5.92e-08	117	119	9	PS50888
Domain	bHLH_dom	MYCN TFEB TCF3 TCF12 PTF1A TFAP4 TFE3 ASCL1 MITF	6.37e-08	118	119	9	IPR011598
Domain	MITF_TFEB_C_3_N	TFEB TFE3 MITF	2.52e-07	3	119	3	PF15951
Domain	MiT/TFE_N	TFEB TFE3 MITF	2.52e-07	3	119	3	IPR031867
Domain	DUF3371	TFEB TFE3 MITF	1.00e-06	4	119	3	PF11851
Domain	MiT/TFE_C	TFEB TFE3 MITF	1.00e-06	4	119	3	IPR021802
Domain	DUF3669_Znf	ZNF783 ZNF398 ZNF282	4.97e-06	6	119	3	IPR022137
Domain	DUF3669	ZNF783 ZNF398 ZNF282	4.97e-06	6	119	3	PF12417
Domain	PH	PHLDB3 BCR SPTBN4 ARHGAP22 PHLDB1 DEF6 OSBPL5 PLEKHM3 CADPS2	1.61e-05	229	119	9	PF00169
Domain	PH	PHLDB3 BCR SPTBN4 ARHGAP22 PHLDB1 DEF6 OSBPL5 PLEKHM3 CADPS2	7.31e-05	278	119	9	SM00233
Domain	PH_DOMAIN	PHLDB3 BCR SPTBN4 ARHGAP22 PHLDB1 DEF6 OSBPL5 PLEKHM3 CADPS2	7.51e-05	279	119	9	PS50003
Domain	PH_domain	PHLDB3 BCR SPTBN4 ARHGAP22 PHLDB1 DEF6 OSBPL5 PLEKHM3 CADPS2	7.72e-05	280	119	9	IPR001849
Domain	CH	EHBP1 MICAL1 CAMSAP3 SPTBN4 PLEC	8.39e-05	70	119	5	PF00307
Domain	CH	EHBP1 MICAL1 CAMSAP3 SPTBN4 PLEC	1.03e-04	73	119	5	PS50021
Domain	CH-domain	EHBP1 MICAL1 CAMSAP3 SPTBN4 PLEC	1.17e-04	75	119	5	IPR001715
Domain	ZF_CCHC_NOA	TNIP2 IKBKG	1.20e-04	3	119	2	PS51801
Domain	-	PHLDB3 BCR SPTBN4 ARHGAP22 PHLDB1 DEF6 OSBPL5 PLEKHM3 CADPS2 HOMER3	2.02e-04	391	119	10	2.30.29.30
Domain	-	SAFB SLTM SAFB2	3.08e-04	21	119	3	1.10.720.30
Domain	SAP	SAFB SLTM SAFB2	3.56e-04	22	119	3	PF02037
Domain	Anaphylatoxin_comp_syst	C4A C4B	3.98e-04	5	119	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	3.98e-04	5	119	2	IPR001840
Domain	PH_dom-like	PHLDB3 BCR SPTBN4 ARHGAP22 PHLDB1 DEF6 OSBPL5 PLEKHM3 CADPS2 HOMER3	4.00e-04	426	119	10	IPR011993
Domain	SAP	SAFB SLTM SAFB2	4.07e-04	23	119	3	SM00513
Domain	SAP	SAFB SLTM SAFB2	5.24e-04	25	119	3	PS50800
Domain	SAP_dom	SAFB SLTM SAFB2	5.24e-04	25	119	3	IPR003034
Domain	-	EVPL PLEC	5.94e-04	6	119	2	3.90.1290.10
Domain	RRM	PPRC1 ABT1 SAFB G3BP1 SLTM SAFB2 PSPC1	6.83e-04	230	119	7	PS50102
Domain	CH	EHBP1 MICAL1 SPTBN4 PLEC	7.86e-04	65	119	4	SM00033
Domain	Spectrin_repeat	EVPL SPTBN4 PLEC	8.17e-04	29	119	3	IPR002017
Domain	ANATO	C4A C4B	8.28e-04	7	119	2	SM00104
Domain	Plectin_repeat	EVPL PLEC	8.28e-04	7	119	2	IPR001101
Domain	ANATO	C4A C4B	8.28e-04	7	119	2	PF01821
Domain	Plectin	EVPL PLEC	8.28e-04	7	119	2	PF00681
Domain	DUF3585	EHBP1 MICAL1	8.28e-04	7	119	2	IPR022735
Domain	ANAPHYLATOXIN_2	C4A C4B	8.28e-04	7	119	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	8.28e-04	7	119	2	PS01177
Domain	DUF3585	EHBP1 MICAL1	8.28e-04	7	119	2	PF12130
Domain	Anaphylatoxin/fibulin	C4A C4B	8.28e-04	7	119	2	IPR000020
Domain	PLEC	EVPL PLEC	8.28e-04	7	119	2	SM00250
Domain	-	PPRC1 ABT1 SAFB G3BP1 SLTM SAFB2 PSPC1	9.66e-04	244	119	7	3.30.70.330
Domain	Spectrin/alpha-actinin	EVPL SPTBN4 PLEC	1.09e-03	32	119	3	IPR018159
Domain	SPEC	EVPL SPTBN4 PLEC	1.09e-03	32	119	3	SM00150
Domain	-	EHBP1 MICAL1 SPTBN4 PLEC	1.10e-03	71	119	4	1.10.418.10
Domain	Thiol-ester_cl	C4A C4B	1.10e-03	8	119	2	PF10569
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	1.10e-03	8	119	2	IPR019565
Domain	MacrogloblnA2_CS	C4A C4B	1.10e-03	8	119	2	IPR019742
Domain	Nucleotide-bd_a/b_plait	PPRC1 ABT1 SAFB G3BP1 SLTM SAFB2 PSPC1	1.33e-03	258	119	7	IPR012677
Domain	ZF_CCHC	TUT7 ZCCHC17 PNMA3	1.42e-03	35	119	3	PS50158
Domain	A2M_N	C4A C4B	1.75e-03	10	119	2	PF01835
Domain	A2M_N	C4A C4B	1.75e-03	10	119	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	1.75e-03	10	119	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	1.75e-03	10	119	2	PS00477
Domain	A2M	C4A C4B	1.75e-03	10	119	2	PF00207
Domain	A2M_N_2	C4A C4B	1.75e-03	10	119	2	IPR011625
Domain	A2M_comp	C4A C4B	1.75e-03	10	119	2	IPR011626
Domain	A2M_N_2	C4A C4B	1.75e-03	10	119	2	PF07703
Domain	A2M_recep	C4A C4B	1.75e-03	10	119	2	PF07677
Domain	A2M_comp	C4A C4B	1.75e-03	10	119	2	PF07678
Domain	PTX	PTX4 SVEP1	1.75e-03	10	119	2	SM00159
Domain	Macroglobln_a2	C4A C4B	1.75e-03	10	119	2	IPR001599
Domain	Pentaxin-related	PTX4 SVEP1	2.13e-03	11	119	2	IPR001759
Domain	NTP_transf_2	TUT7 OAS1	2.13e-03	11	119	2	PF01909
Domain	Pentaxin	PTX4 SVEP1	2.13e-03	11	119	2	PF00354
Domain	Polymerase_NTP_transf_dom	TUT7 OAS1	2.13e-03	11	119	2	IPR002934
Domain	RRM_1	PPRC1 SAFB G3BP1 SLTM SAFB2 PSPC1	2.17e-03	208	119	6	PF00076
Domain	RRM	PPRC1 SAFB G3BP1 SLTM SAFB2 PSPC1	2.68e-03	217	119	6	SM00360
Domain	Galactose-bd-like	MYCBP2 LAMB2 LAMB3 HECTD1	3.07e-03	94	119	4	IPR008979
Domain	RRM_dom	PPRC1 SAFB G3BP1 SLTM SAFB2 PSPC1	3.35e-03	227	119	6	IPR000504
Domain	Laminin_N	LAMB2 LAMB3	4.56e-03	16	119	2	IPR008211
Domain	LAMININ_NTER	LAMB2 LAMB3	4.56e-03	16	119	2	PS51117
Domain	Laminin_N	LAMB2 LAMB3	4.56e-03	16	119	2	PF00055
Domain	LamNT	LAMB2 LAMB3	4.56e-03	16	119	2	SM00136
Domain	C345C	C4A C4B	5.14e-03	17	119	2	SM00643
Domain	ZnF_C2HC	TUT7 ZCCHC17 PNMA3	5.20e-03	55	119	3	SM00343
Domain	Znf_CCHC	TUT7 ZCCHC17 PNMA3	5.20e-03	55	119	3	IPR001878
Domain	UIM	ANKRD13B HGS	5.76e-03	18	119	2	PF02809
Domain	Myosin_tail_1	MYH14 CCDC102A	5.76e-03	18	119	2	PF01576
Domain	Myosin_tail	MYH14 CCDC102A	5.76e-03	18	119	2	IPR002928
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B	5.76e-03	18	119	2	IPR008930
Pathway	REACTOME_OVARIAN_TUMOR_DOMAIN_PROTEASES	RIPK1 TNIP2 IKBKG YOD1	4.66e-05	32	89	4	MM15290
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 PHLDB3 TFEB CHMP6 OFD1 MYCBP2 KIF26A PPRC1 LAD1 LAMB2 LAMB3 BCR TFE3 PPP1R26 PHLDB1 DEF6 OSBPL5 ZNF398 MAP3K11 PLEC HECTD1 GCN1	6.82e-11	1105	125	22	35748872
Pubmed	Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.	MYCN TFEB TCF3 TCF12 PTF1A TFAP4 TFE3 ASCL1 MITF	8.98e-11	98	125	9	18557763
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	MYCBP2 TNIP2 DBNL LAMB2 N4BP3 CXXC1 SPTBN4 ARHGAP22 PHLDB1 CEP89 HGS SAFB2 JAKMIP1 PSPC1 HOMER3	1.88e-09	560	125	15	21653829
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	TCF3 TCF12 RIPK1 OFD1 MYCBP2 TUT7 GGCX G3BP1 MYH14 DNAJC11 GIGYF2 JAKMIP1 HECTD1 GCN1 PBXIP1 GPRASP2 CUX1	1.95e-09	754	125	17	33060197
Pubmed	A human MAP kinase interactome.	EHBP1 RIPK1 KIF26A LAMB2 EVPL RMDN3 HGS MAP3K11 GIGYF2 C4A PLEC GCN1 CUX1	2.44e-08	486	125	13	20936779
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	EHBP1 TFEB ATG16L1 TCF3 TCF12 RIPK1 TNIP2 CAVIN3 N4BP3 BCR TFE3 PHLDB1 TFPT SLC7A6OS DNAJC11 MITF GIGYF2 AMOTL2	3.62e-08	1038	125	18	26673895
Pubmed	The inhibitor ABIN-2 disrupts the interaction of receptor-interacting protein with the kinase subunit IKKgamma to block activation of the transcription factor NF-kappaB and potentiate apoptosis.	RIPK1 TNIP2 IKBKG	4.53e-08	3	125	3	14653779
Pubmed	Nuclear targeting of the transcription factor PTF1 is mediated by a protein subunit that does not bind to the PTF1 cognate sequence.	TCF3 TCF12 PTF1A	4.53e-08	3	125	3	1720355
Pubmed	Expression of the proneural gene encoding Mash1 suppresses MYCN mitotic activity.	MYCN CCND2 ASCL1	4.53e-08	3	125	3	19208763
Pubmed	MITF and TFEB cross-regulation in melanoma cells.	TFEB TFE3 MITF	4.53e-08	3	125	3	32881934
Pubmed	Role of the basic helix-loop-helix transcription factor p48 in the differentiation phenotype of exocrine pancreas cancer cells.	TCF3 TCF12 PTF1A	4.53e-08	3	125	3	10768861
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	EHBP1 TFEB OFD1 MYCBP2 DBNL CAMSAP3 DNM1L N4BP3 BCR PHLDB1 CEP89 GIGYF2 PLEKHM3 PLEC HECTD1 CCDC102A	8.76e-08	861	125	16	36931259
Pubmed	Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development.	TFEB TFE3 MITF	1.81e-07	4	125	3	11930005
Pubmed	Cloning and characterization of the murine genes for bHLH-ZIP transcription factors TFEC and TFEB reveal a common gene organization for all MiT subfamily members.	TFEB TFE3 MITF	1.81e-07	4	125	3	10036191
Pubmed	Olig3 regulates early cerebellar development.	MYCN TCF3 TCF12 PTF1A ASCL1	3.29e-07	40	125	5	33591268
Pubmed	Ubiquitin Specific Peptidase 15 (USP15) suppresses glioblastoma cell growth via stabilization of HECTD1 E3 ligase attenuating WNT pathway activity.	DNM1L RMDN3 C4A HECTD1	3.65e-07	17	125	4	29299163
Pubmed	A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection.	OFD1 DNM1L SPTBN4 YOD1 SAFB2 C4A SCLT1 HOMER3	4.48e-07	189	125	8	31594818
Pubmed	mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases.	TFEB TFE3 MITF	4.51e-07	5	125	3	28165011
Pubmed	Sumoylation of MITF and its related family members TFE3 and TFEB.	TFEB TFE3 MITF	4.51e-07	5	125	3	15507434
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MICAL1 DBNL CAMSAP3 DNM1L BCR SPTBN4 CRACD PHLDB1 SAFB G3BP1 MYH14 C4A C4B PLEC CROCC TNNT2 PSPC1 PBXIP1 HOMER3	8.90e-07	1431	125	19	37142655
Pubmed	RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases.	ATG16L1 RIPK1 IKBKG	8.99e-07	6	125	3	31101885
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	TUT7 ABT1 DDX51 ZCCHC17 CACTIN RPUSD4 SAFB G3BP1 SLTM SAFB2 GIGYF2 PSPC1 GCN1 SF3A2	1.33e-06	807	125	14	22681889
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	MYCN TFEB TCF12 TUT7 IKBKG ABT1 CXXC1 ATF6B TFAP4 TFE3 SLTM ZNF398 ZNF282 CUX1	1.35e-06	808	125	14	20412781
Pubmed	A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.	TCF12 RIPK1 MYCBP2 GGCX G3BP1 DNAJC11 GIGYF2 JAKMIP1 HECTD1	1.42e-06	298	125	9	32353859
Pubmed	Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins.	RIPK1 TNIP2 IKBKG	1.57e-06	7	125	3	18212736
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	MICAL1 ATG16L1 TUT7 DBNL ZCCHC17 CACTIN RPUSD4 SAFB DEF6 SLTM SAFB2 PLEC GCN1	1.57e-06	701	125	13	30196744
Pubmed	Widespread macromolecular interaction perturbations in human genetic disorders.	ISYNA1 TCF12 PGBD1 OAS1 CCND2 TFPT NDUFAF4 HGS TRAF3IP3 AMOTL2 HOMER3 GPRASP2	1.57e-06	590	125	12	25910212
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	TCF12 RIPK1 LAD1 LAMB3 MISP3 ABT1 CRACD G3BP1 MYH14 JAKMIP1 PLEC	2.19e-06	503	125	11	36217030
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	EVPL ABT1 DDX51 TFAP4 SAFB G3BP1 MYH14 SLTM SAFB2 GIGYF2 C4A PSPC1 SF3A2 CUX1	2.34e-06	847	125	14	35850772
Pubmed	The bHLH-Zip transcription factor Tfeb is essential for placental vascularization.	TFEB TFE3 MITF	2.50e-06	8	125	3	9806910
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	EHBP1 MYCBP2 CAMSAP3 IKBKG BCR GIGYF2 PLEC GCN1 GPRASP2 CUX1	2.93e-06	418	125	10	34709266
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	MYCBP2 N4BP3 BCR TFAP4 YOD1 TFPT SAFB G3BP1 GIGYF2 PLEC SCLT1 HECTD1 GCN1 SF3A2 GPRASP2	3.47e-06	1005	125	15	19615732
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MYCBP2 PPRC1 ZNF365 SPTBN4 MYH14 ASCL1 MAP3K11 JAKMIP1 PLEC AMOTL2 CADPS2 ZNHIT1 HECTD1 PBXIP1 SF3A2 GPRASP2 CUX1	3.72e-06	1285	125	17	35914814
Pubmed	Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors.	TCF3 TCF12 ASCL1	3.75e-06	9	125	3	8948587
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CHMP6 OFD1 MYCBP2 LAMB2 PHLDB1 SAFB G3BP1 MYH14 SLTM SAFB2 GIGYF2 PLEC PSPC1 GCN1 SF3A2	4.34e-06	1024	125	15	24711643
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	MYCN TFEB TCF12 PTF1A ATF6B TFAP4 TFE3 HOXC12 ASCL1 ZNF282 CUX1	4.62e-06	544	125	11	28473536
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	MYCBP2 TNIP2 ZCCHC17 GGCX SPTBN4 PHLDB1 SAFB SLTM CADPS2	6.73e-06	361	125	9	26167880
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	EHBP1 DBNL DNM1L GGCX CEMIP2 RMDN3 GIGYF2 CROCC GCN1 PBXIP1 CUX1	6.93e-06	568	125	11	37774976
Pubmed	Involvement of Ymer in suppression of NF-kappaB activation by regulated interaction with lysine-63-linked polyubiquitin chain.	RIPK1 TNIP2 IKBKG	9.74e-06	12	125	3	18029035
Pubmed	An inter-species protein-protein interaction network across vast evolutionary distance.	IKBKG ZCCHC17 USH1C TFPT HGS CCDC120 AMOTL2 HOMER3 GPRASP2 CCDC85B	1.04e-05	483	125	10	27107014
Pubmed	Binding of USP4 to cortactin enhances cell migration in HCT116 human colon cancer cells.	LAD1 DBNL EVPL CACTIN PLEC GCN1	1.07e-05	137	125	6	37039823
Pubmed	Downregulation of E Protein Activity Augments an ILC2 Differentiation Program in the Thymus.	TCF3 TCF12	1.28e-05	2	125	2	28258196
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	1.28e-05	2	125	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	1.28e-05	2	125	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	1.28e-05	2	125	2	15998580
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	1.28e-05	2	125	2	19062096
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	1.28e-05	2	125	2	19933335
Pubmed	Molecular genetics and cellular features of TFE3 and TFEB fusion kidney cancers.	TFEB TFE3	1.28e-05	2	125	2	25048860
Pubmed	Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors.	TCF3 TCF12	1.28e-05	2	125	2	18093538
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	1.28e-05	2	125	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	1.28e-05	2	125	2	17645767
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	1.28e-05	2	125	2	12207352
Pubmed	Scaffold attachment factors SAFB1 and SAFB2: Innocent bystanders or critical players in breast tumorigenesis?	SAFB SAFB2	1.28e-05	2	125	2	14587024
Pubmed	TFEB and TFE3: The art of multi-tasking under stress conditions.	TFEB TFE3	1.28e-05	2	125	2	27892768
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	1.28e-05	2	125	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	1.28e-05	2	125	2	22387014
Pubmed	Diagnostic utility of one-stop fusion gene panel to detect TFE3/TFEB gene rearrangement and amplification in renal cell carcinomas.	TFEB TFE3	1.28e-05	2	125	2	34148064
Pubmed	Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB.	TCF3 TCF12	1.28e-05	2	125	2	10958665
Pubmed	An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells.	TCF3 TCF12	1.28e-05	2	125	2	20154672
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	1.28e-05	2	125	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	1.28e-05	2	125	2	23918728
Pubmed	E2A promotes the survival of precursor and mature B lymphocytes.	TCF3 TCF12	1.28e-05	2	125	2	16888011
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	1.28e-05	2	125	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	1.28e-05	2	125	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	1.28e-05	2	125	2	4216347
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	1.28e-05	2	125	2	6950384
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	1.28e-05	2	125	2	8660986
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	1.28e-05	2	125	2	8428773
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	1.28e-05	2	125	2	24638111
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	1.28e-05	2	125	2	21345967
Pubmed	E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression.	TCF3 TCF12	1.28e-05	2	125	2	17442955
Pubmed	TFEB/3 Govern Repair Schwann Cell Generation and Function Following Peripheral Nerve Injury.	TFEB TFE3	1.28e-05	2	125	2	39054068
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	1.28e-05	2	125	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	1.28e-05	2	125	2	2302180
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	1.28e-05	2	125	2	22151770
Pubmed	The identification and functional characterization of a novel mast cell isoform of the microphthalmia-associated transcription factor.	TFE3 MITF	1.28e-05	2	125	2	12039954
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	1.28e-05	2	125	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	1.28e-05	2	125	2	29080553
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	1.28e-05	2	125	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	1.28e-05	2	125	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	1.28e-05	2	125	2	17728371
Pubmed	Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers.	TFE3 MITF	1.28e-05	2	125	2	16766266
Pubmed	Structure and organization of the C4 genes.	C4A C4B	1.28e-05	2	125	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	1.28e-05	2	125	2	6149581
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	1.28e-05	2	125	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	1.28e-05	2	125	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	1.28e-05	2	125	2	2387317
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	1.28e-05	2	125	2	16908004
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	1.28e-05	2	125	2	7365238
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	1.28e-05	2	125	2	7391573
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	1.28e-05	2	125	2	17971360
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	1.28e-05	2	125	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	1.28e-05	2	125	2	17971229
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	1.28e-05	2	125	2	6881182
Pubmed	Correlation between circulating innate lymphoid cell precursors and thymic function.	TCF3 TCF12	1.28e-05	2	125	2	35118353
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	1.28e-05	2	125	2	17921792
Pubmed	Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.	C4A C4B	1.28e-05	2	125	2	21880985
Pubmed	Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.	C4A C4B	1.28e-05	2	125	2	6978711
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	1.28e-05	2	125	2	35898513
Pubmed	BMP-2 decreases Mash1 stability by increasing Id1 expression.	TCF3 ASCL1	1.28e-05	2	125	2	15318167
Interaction	YWHAH interactions	EHBP1 TFEB ATG16L1 EVC2 OFD1 MYCBP2 DBNL CAMSAP3 DNM1L N4BP3 BCR TFE3 RMDN3 PHLDB1 G3BP1 CEP89 CBY1 MITF OSBPL5 GIGYF2 PLEKHM3 JAKMIP1 PLEC AMOTL2 HECTD1 HOMER3	2.16e-09	1102	123	26	int:YWHAH
Interaction	YWHAG interactions	MYCN EHBP1 TFEB ATG16L1 MYCBP2 TNIP2 DBNL CAMSAP3 DNM1L N4BP3 BCR TFE3 RMDN3 CRACD PHLDB1 CEP89 CBY1 MITF GIGYF2 PLEKHM3 JAKMIP1 AMOTL2 HECTD1 GPRASP2 CCDC102A	1.16e-07	1248	123	25	int:YWHAG
Interaction	YWHAB interactions	MYCN TFEB ATG16L1 MYCBP2 CAMSAP3 DNM1L N4BP3 BCR TFE3 RMDN3 PHLDB1 G3BP1 CEP89 CBY1 HGS MITF GIGYF2 PLEKHM3 JAKMIP1 AMOTL2 HECTD1 GPRASP2	1.95e-07	1014	123	22	int:YWHAB
Interaction	RCOR1 interactions	EHBP1 PHLDB3 TCF3 MYCBP2 CAMSAP3 IKBKG LAMB2 BCR TFPT GIGYF2 PLEC SCLT1 GCN1 GPRASP2 CUX1	3.47e-07	494	123	15	int:RCOR1
Interaction	ATG16L1 interactions	TFEB MICAL1 ATG16L1 OFD1 MYCBP2 TUT7 DBNL IKBKG ZCCHC17 NLRP6 CACTIN RPUSD4 PHLDB1 SAFB CEP89 DEF6 MITF SLTM SAFB2 TRAF3IP3 PLEC GCN1 CCDC102A	4.93e-07	1161	123	23	int:ATG16L1
Interaction	TOP3B interactions	VWA5B2 MYCN PHLDB3 TFEB CHMP6 OFD1 MYCBP2 KIF26A PPRC1 LAD1 LAMB2 LAMB3 BCR TFE3 PPP1R26 PHLDB1 SAFB G3BP1 DEF6 OSBPL5 SAFB2 ZNF398 MAP3K11 PLEC HECTD1 GCN1	6.90e-07	1470	123	26	int:TOP3B
Interaction	KDM1A interactions	MYCN EHBP1 PHLDB3 ATG16L1 TCF3 OFD1 MYCBP2 CAMSAP3 IKBKG ZCCHC17 BCR GIGYF2 PLEC SCLT1 TNNT2 PSPC1 GCN1 HOMER3 GPRASP2 CUX1	1.04e-06	941	123	20	int:KDM1A
Interaction	YWHAE interactions	MYCN TFEB ATG16L1 MYCBP2 TNIP2 DBNL CAMSAP3 DNM1L N4BP3 BCR TFE3 RMDN3 CRACD PHLDB1 G3BP1 CEP89 CBY1 GIGYF2 PLEKHM3 JAKMIP1 AMOTL2 HECTD1 HOMER3	1.91e-06	1256	123	23	int:YWHAE
Interaction	FCHSD2 interactions	HGS CCDC120 CCDC183 TSGA10IP GPRASP2 CCDC85B	2.81e-06	65	123	6	int:FCHSD2
Interaction	NHLRC2 interactions	TBXAS1 TFEB RIPK1 OFD1 DNM1L SPTBN4 YOD1 DEF6 SAFB2 C4A SCLT1 HOMER3	3.25e-06	375	123	12	int:NHLRC2
Interaction	FXR1 interactions	MYCN ATG16L1 MYCBP2 N4BP3 ATF6B ARHGAP22 HABP4 PHLDB1 G3BP1 CEP89 SAFB2 GIGYF2 JAKMIP1 PSPC1 HECTD1 HOMER3	3.84e-06	679	123	16	int:FXR1
Interaction	CEP170 interactions	MYCN ATG16L1 OFD1 EMILIN1 TFPT CEP89 CBY1 CCDC120 SCLT1 PSPC1 HECTD1	4.07e-06	318	123	11	int:CEP170
Interaction	TANK interactions	ATG16L1 RIPK1 OFD1 TNIP2 IKBKG YOD1 GIGYF2 PLEC PBXIP1	7.23e-06	216	123	9	int:TANK
Interaction	CCDC138 interactions	OFD1 IKBKG RMDN3 CEP89 TRAF3IP3 SCLT1 PBXIP1	1.05e-05	123	123	7	int:CCDC138
Interaction	HAND1 interactions	MYCN TCF3 TCF12 ASCL1	1.28e-05	24	123	4	int:HAND1
Interaction	YWHAQ interactions	MYCN TFEB ATG16L1 TCF3 MYCBP2 CAMSAP3 DNM1L N4BP3 BCR TFE3 RMDN3 PHLDB1 G3BP1 CEP89 CBY1 PLEKHM3 PLEC AMOTL2 HECTD1 GCN1	1.38e-05	1118	123	20	int:YWHAQ
Interaction	SAFB interactions	MYCN ATG16L1 TCF3 DNM1L GGCX SAFB G3BP1 SAFB2 GCN1	1.91e-05	244	123	9	int:SAFB
Interaction	PNMA2 interactions	CAMSAP3 N4BP3 BCR ZNF783 RPUSD4 SAFB2 GIGYF2 ZNF282 CCDC102A	2.39e-05	251	123	9	int:PNMA2
Interaction	LINC02910 interactions	CACTIN HABP4 SAFB SLTM SAFB2 GIGYF2	2.55e-05	95	123	6	int:LINC02910
Interaction	SRPK2 interactions	MYCN ATG16L1 MYCBP2 TNIP2 DDX51 ZCCHC17 GGCX CACTIN PHLDB1 SAFB SLTM CADPS2 PSPC1 HECTD1 HOMER3	3.18e-05	717	123	15	int:SRPK2
Interaction	ZNF638 interactions	MYCN ATG16L1 TNIP2 TFE3 TFPT G3BP1 CBY1 GIGYF2 CCDC85B	3.25e-05	261	123	9	int:ZNF638
Interaction	TPM1 interactions	MYCN IKBKG DNM1L TFPT G3BP1 CROCC SCLT1 TNNT2 CCDC102A	3.45e-05	263	123	9	int:TPM1
Interaction	DEF6 interactions	ATG16L1 MYCBP2 ARHGAP22 DEF6 PBXIP1	3.53e-05	61	123	5	int:DEF6
Interaction	NEUROG3 interactions	TCF3 TCF12 DDX51 RMDN3 GIGYF2 PLEC GCN1	3.64e-05	149	123	7	int:NEUROG3
Interaction	HDAC1 interactions	ANKRD13B MYCN EHBP1 ATG16L1 MYCBP2 CAMSAP3 IKBKG BCR TFAP4 TFE3 G3BP1 MYH14 GIGYF2 PLEC CROCC HECTD1 GCN1 GPRASP2 CUX1	4.16e-05	1108	123	19	int:HDAC1
Interaction	NUP62 interactions	MYCN TNIP2 CAVIN3 ARHGAP22 G3BP1 HGS SAFB2 AMOTL2 CUX1	4.61e-05	273	123	9	int:NUP62
Interaction	YWHAZ interactions	MYCN TFEB ATG16L1 MYCBP2 CAMSAP3 DNM1L N4BP3 BCR TFE3 RMDN3 CRACD PHLDB1 CEP89 CBY1 MAP3K11 GIGYF2 PLEKHM3 JAKMIP1 PLEC HECTD1 HOMER3	4.63e-05	1319	123	21	int:YWHAZ
Interaction	IFI27L1 interactions	CACTIN HABP4 SAFB SLTM SAFB2	4.81e-05	65	123	5	int:IFI27L1
Interaction	PHF21A interactions	EHBP1 PHLDB3 MYCBP2 IKBKG BCR TFPT GIGYF2 PLEC SCLT1 GPRASP2	4.90e-05	343	123	10	int:PHF21A
Interaction	ANKRD50 interactions	ATG16L1 CACTIN HABP4 MYH14 SLTM SAFB2	5.27e-05	108	123	6	int:ANKRD50
Interaction	SRBD1 interactions	MYCN ABT1 ARHGAP22 CEP89 CROCC HECTD1	5.84e-05	110	123	6	int:SRBD1
Interaction	RSBN1 interactions	PPRC1 ABT1 DDX51 CXXC1 SPTBN4 PSPC1 HECTD1	5.96e-05	161	123	7	int:RSBN1
Interaction	KRT222 interactions	ATG16L1 PLEC CROCC CCDC102A	5.98e-05	35	123	4	int:KRT222
Interaction	MRFAP1L1 interactions	OFD1 TNIP2 IKBKG CAVIN3 ZNF783 HGS	6.45e-05	112	123	6	int:MRFAP1L1
Interaction	CCDC59 interactions	MYCN TNIP2 TUT7 DDX51 HECTD1 GPRASP2	6.45e-05	112	123	6	int:CCDC59
Interaction	FXR2 interactions	MYCN TNIP2 ZCCHC17 HABP4 PHLDB1 G3BP1 AMOTL2 PSPC1 HECTD1 HOMER3 CCDC85B	6.64e-05	430	123	11	int:FXR2
Interaction	RTRAF interactions	MYCN TCF3 TNIP2 DNM1L ABT1 G3BP1 PSPC1 HECTD1	6.64e-05	222	123	8	int:RTRAF
Interaction	DCTN2 interactions	EHBP1 OFD1 TNIP2 DNM1L BCR EMILIN1 CCND2 HGS SCLT1 HECTD1	6.68e-05	356	123	10	int:DCTN2
Interaction	TRIM27 interactions	ATG16L1 TCF3 RIPK1 TNIP2 OAS1 ABT1 ARHGAP22 TFPT ASCL1 HGS AMOTL2 TSGA10IP	7.37e-05	514	123	12	int:TRIM27
Interaction	HNRNPDL interactions	MYCN ATG16L1 TNIP2 DNM1L GGCX RMDN3 RPUSD4 HGS PSPC1 HECTD1	8.03e-05	364	123	10	int:HNRNPDL
Interaction	SNRPC interactions	MYCN ATG16L1 OFD1 PPRC1 TNIP2 CACTIN HABP4 SAFB SAFB2 GIGYF2 SF3A2	8.15e-05	440	123	11	int:SNRPC
Interaction	NDE1 interactions	ATG16L1 OFD1 ZNF365 SPTBN4 ZNF398 CCDC183	8.23e-05	117	123	6	int:NDE1
Interaction	SFN interactions	TCF3 MYCBP2 LAD1 CAMSAP3 DNM1L N4BP3 BCR TFE3 PHLDB1 G3BP1 CEP89 CBY1 PLEC HECTD1	8.48e-05	692	123	14	int:SFN
Interaction	TUT7 interactions	MYCN ATG16L1 TUT7 ABT1 RMDN3 HECTD1	8.63e-05	118	123	6	int:TUT7
Interaction	KRT38 interactions	ATG16L1 OFD1 HGS CCDC120 AMOTL2 CCDC102A CCDC85B	9.03e-05	172	123	7	int:KRT38
Interaction	TFEC interactions	TFEB TFE3 MITF	9.57e-05	15	123	3	int:TFEC
Interaction	PSMD9 interactions	PHLDB3 ATG16L1 TCF3 ISYNA1 TNIP2 TFPT AMOTL2	1.04e-04	176	123	7	int:PSMD9
Interaction	FMR1 interactions	MYCN ATG16L1 MYCBP2 TNIP2 HABP4 G3BP1 SAFB2 GIGYF2 PSPC1 HECTD1 HOMER3 CUX1	1.09e-04	536	123	12	int:FMR1
Interaction	BAG2 interactions	VWA5B2 MYCN TFEB EVC2 RIPK1 OFD1 TNIP2 DBNL LAMB3 CXXC1 DNAJC11 HGS SF3A2	1.12e-04	622	123	13	int:BAG2
Interaction	ARMC8 interactions	TCF12 NATD1 LAD1 ARHGAP22 NDUFAF4 HGS CCDC120 HECTD1	1.14e-04	240	123	8	int:ARMC8
Interaction	CSNK1A1 interactions	MYCN ATG16L1 MYCBP2 IKBKG BCR ARHGAP22 HABP4 CBY1 GCN1 SF3A2	1.17e-04	381	123	10	int:CSNK1A1
Interaction	PTF1A interactions	TCF3 TCF12 PTF1A	1.17e-04	16	123	3	int:PTF1A
Interaction	ZNF767P interactions	ZNF783 ZNF398 ZNF282	1.17e-04	16	123	3	int:ZNF767P
Interaction	TP53BP2 interactions	OFD1 EMILIN1 YOD1 CEP89 PLEC AMOTL2 SCLT1 CCDC85B	1.18e-04	241	123	8	int:TP53BP2
Interaction	DOT1L interactions	MYCN EVPL ABT1 DDX51 TFAP4 SAFB G3BP1 MYH14 SLTM SAFB2 GIGYF2 C4A PSPC1 SF3A2 CUX1	1.20e-04	807	123	15	int:DOT1L
Interaction	INO80E interactions	TCF3 ACTR5 IKBKG TFAP4 TFPT	1.23e-04	79	123	5	int:INO80E
Interaction	EXOSC7 interactions	MYCN ATG16L1 GIGYF2 PSPC1 HECTD1 SF3A2	1.29e-04	127	123	6	int:EXOSC7
Interaction	CBLN4 interactions	MYCN ATG16L1 CHST14 LAMB2 CEMIP2 PBXIP1	1.29e-04	127	123	6	int:CBLN4
Interaction	CCDC14 interactions	ATG16L1 OFD1 IKBKG CEP89 CCDC183 SCLT1	1.41e-04	129	123	6	int:CCDC14
Interaction	ELAVL2 interactions	MYCN TCF3 SAFB G3BP1 SAFB2 PSPC1 HECTD1	1.57e-04	188	123	7	int:ELAVL2
Interaction	GAN interactions	ATG16L1 EPX PHLDB1 MYH14 CBY1 PLEC CROCC CUX1	1.64e-04	253	123	8	int:GAN
Interaction	DNMT1 interactions	MYCN ATG16L1 TCF3 TNIP2 CXXC1 MYH14 HECTD1 GCN1	1.69e-04	254	123	8	int:DNMT1
Interaction	NUP54 interactions	ATG16L1 G3BP1 HGS SCLT1 HOMER3 CCDC85B	1.88e-04	136	123	6	int:NUP54
Interaction	CCDC8 interactions	CHMP6 OFD1 MYCBP2 LAMB2 EMILIN1 PHLDB1 G3BP1 MYH14 GIGYF2 PLEC HECTD1 GCN1 GPRASP2	1.89e-04	656	123	13	int:CCDC8
Interaction	LTV1 interactions	MYCN ATG16L1 ABT1 USH1C BCR G3BP1 HECTD1	2.03e-04	196	123	7	int:LTV1
Interaction	PALS1 interactions	ATG16L1 TNIP2 IKBKG AMOTL2 HOMER3	2.15e-04	89	123	5	int:PALS1
Interaction	RALBP1 interactions	PHLDB3 ATG16L1 IKBKG TFPT CBY1 AMOTL2 CROCC	2.16e-04	198	123	7	int:RALBP1
Interaction	GIT2 interactions	PHLDB3 ATG16L1 IKBKG TFPT SAFB2 ZNHIT1	2.20e-04	140	123	6	int:GIT2
Interaction	HSPA4 interactions	MYCN ATG16L1 OFD1 TNIP2 IKBKG DNM1L BCR TFE3 G3BP1 MYH14 MAP3K11 SCLT1 HECTD1	2.22e-04	667	123	13	int:HSPA4
Interaction	KIFC1 interactions	MYCN ATG16L1 CXXC1 PLEC HECTD1	2.51e-04	92	123	5	int:KIFC1
Interaction	RABGEF1 interactions	PHLDB3 TCF3 TNIP2 EMILIN1 TFPT CCDC183 GPRASP2	2.59e-04	204	123	7	int:RABGEF1
Interaction	IFT57 interactions	EHBP1 ATG16L1 OFD1 SCLT1 HOMER3	2.64e-04	93	123	5	int:IFT57
Interaction	TFEB interactions	TFEB ATG16L1 TFE3 MITF	2.85e-04	52	123	4	int:TFEB
Interaction	MIS18A interactions	ATG16L1 OFD1 RMDN3 SCLT1 TSGA10IP	3.06e-04	96	123	5	int:MIS18A
Interaction	SDCCAG8 interactions	OFD1 IKBKG CCDC120	3.14e-04	22	123	3	int:SDCCAG8
Interaction	SAA1 interactions	CACTIN SAFB SLTM SAFB2	3.30e-04	54	123	4	int:SAA1
Interaction	DPM2 interactions	CACTIN MYH14 SLTM SAFB2	3.30e-04	54	123	4	int:DPM2
Interaction	CCDC86 interactions	MYCN ABT1 ARHGAP22 HABP4 PSPC1 HECTD1	3.31e-04	151	123	6	int:CCDC86
Interaction	GOLGA6L9 interactions	CAVIN3 HGS DEF6 CCDC120 TRAF3IP3 ZNHIT1 TSGA10IP	3.66e-04	216	123	7	int:GOLGA6L9
Interaction	ZNRD2 interactions	TNIP2 CAMSAP3 RPUSD4 DNAJC11 OSBPL5 SLTM TRAF3IP3 CCDC85B	3.93e-04	288	123	8	int:ZNRD2
Interaction	SLU7 interactions	IKBKG CACTIN DEF6 HECTD1 SF3A2 CCDC85B	3.94e-04	156	123	6	int:SLU7
Interaction	EIF2D interactions	ATG16L1 TNIP2 PSPC1 GCN1	4.06e-04	57	123	4	int:EIF2D
Interaction	DDX21 interactions	MYCN TUT7 DNM1L ABT1 DDX51 ZCCHC17 TFE3 SAFB G3BP1 SLTM SAFB2 PSPC1 HECTD1	4.48e-04	718	123	13	int:DDX21
Interaction	TFPT interactions	PHLDB3 TCF3 ACTR5 LAMB2 TFPT CCDC85B	4.51e-04	160	123	6	int:TFPT
Interaction	SRSF9 interactions	MYCN TNIP2 HABP4 SAFB G3BP1 HECTD1 SF3A2	4.55e-04	224	123	7	int:SRSF9
Interaction	TCF3 interactions	MYCN TCF3 TCF12 PTF1A IKBKG TFPT SAFB ASCL1	4.61e-04	295	123	8	int:TCF3
Interaction	MAGED1 interactions	ATG16L1 TNIP2 G3BP1 HGS CCDC120 RXFP4 TSGA10IP GCN1	4.61e-04	295	123	8	int:MAGED1
Interaction	NCKAP5L interactions	PHLDB3 ATG16L1 OFD1 TNIP2 TFPT	4.84e-04	106	123	5	int:NCKAP5L
Interaction	ACIN1 interactions	MYCN TNIP2 DNM1L EVPL NDUFAF4 SAFB HECTD1 SF3A2	5.27e-04	301	123	8	int:ACIN1
Interaction	CENPQ interactions	ATG16L1 EMILIN1 TFPT SCLT1 HECTD1	5.27e-04	108	123	5	int:CENPQ
Interaction	PNN interactions	MYCN TNIP2 DNM1L ABT1 ZCCHC17 BCR HECTD1 SF3A2	5.38e-04	302	123	8	int:PNN
Interaction	ID3 interactions	TCF3 TCF12 TNIP2 IKBKG	5.61e-04	62	123	4	int:ID3
Interaction	AIM2 interactions	TFAP4 TFE3 SAFB SLTM SAFB2	5.73e-04	110	123	5	int:AIM2
Interaction	INO80D interactions	ACTR5 CXXC1 TFPT	5.83e-04	27	123	3	int:INO80D
Interaction	ISG20L2 interactions	MYCN ABT1 PSPC1 HECTD1	5.96e-04	63	123	4	int:ISG20L2
Interaction	GPATCH1 interactions	MYCN OFD1 CACTIN CEP89 HECTD1	5.97e-04	111	123	5	int:GPATCH1
Interaction	CCDC136 interactions	ABT1 HGS CCDC120 TRAF3IP3 TSGA10IP CCDC85B	6.02e-04	169	123	6	int:CCDC136
Interaction	DDX55 interactions	MYCN ATG16L1 TUT7 ABT1 HABP4 HECTD1	6.02e-04	169	123	6	int:DDX55
Interaction	ZC3H14 interactions	MYCN ATG16L1 TNIP2 ZCCHC17 G3BP1 HECTD1	6.02e-04	169	123	6	int:ZC3H14
Interaction	NGRN interactions	MYCN MYCBP2 TNIP2 ABT1 YOD1 RPUSD4 NDUFAF4	6.05e-04	235	123	7	int:NGRN
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	TCF3 ISYNA1 CAMSAP3 MISP3 CACTIN SAFB SAFB2 HOMER3 SF3A2 ZNF433	6.94e-05	797	125	10	chr19p13
Cytoband	1q32	LAMB3 TRAF3IP3 TNNT2	3.31e-04	49	125	3	1q32
Cytoband	12q24.2	OAS1 GCN1	8.61e-04	16	125	2	12q24.2
Cytoband	7q36.1	ZNF783 ZNF398 ZNF282	1.11e-03	74	125	3	7q36.1
Cytoband	Ensembl 112 genes in cytogenetic band chr1q32	LAD1 LAMB3 YOD1 TRAF3IP3 TNNT2	1.23e-03	290	125	5	chr1q32
Cytoband	Ensembl 112 genes in cytogenetic band chr4p16	EVC2 TNIP2 JAKMIP1 CFAP99	3.27e-03	222	125	4	chr4p16
GeneFamily	Basic helix-loop-helix proteins	MYCN TFEB TCF3 TCF12 PTF1A TFAP4 TFE3 ASCL1 MITF	1.48e-09	110	81	9	420
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PHLDB3 BCR SPTBN4 ARHGAP22 PHLDB1 DEF6 OSBPL5 PLEKHM3 CADPS2	3.49e-07	206	81	9	682
GeneFamily	RNA binding motif containing	PPRC1 SAFB G3BP1 SLTM SAFB2 PSPC1	3.88e-04	213	81	6	725
GeneFamily	EF-hand domain containing\|Plakins	EVPL PLEC	5.45e-04	8	81	2	939
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	6.99e-04	9	81	2	1234
GeneFamily	Laminin subunits	LAMB2 LAMB3	1.27e-03	12	81	2	626
GeneFamily	INO80 complex \|SRCAP complex	ACTR5 TFPT	2.00e-03	15	81	2	595
GeneFamily	Zinc fingers CCHC-type\|RNA binding motif containing	TUT7 ZCCHC17	5.56e-03	25	81	2	74
Drug	Molindone hydrochloride [15622-65-8]; Down 200; 12.8uM; MCF7; HT_HG-U133A	RIPK1 EVPL BCR CXXC1 CACTIN MYH14 MITF PLEC HOMER3	1.34e-06	195	125	9	4784_DN
Drug	PHA-00816795 [212631-79-3]; Up 200; 10uM; PC3; HT_HG-U133A	OAS1 ZNF783 PRR7 PHLDB1 SAFB MYH14 DEF6 SAFB2 CUX1	1.52e-06	198	125	9	7076_UP
Drug	AC1L4GYE	EVPL C4A CUX1	3.19e-06	6	125	3	CID000156861
Drug	2-propylpentanoic acid; Down 200; 1000uM; PC3; HG-U133A	TCF3 EVPL EPX ASCL1 DEF6 PLEC SF3A2 PNMA3	1.21e-05	194	125	8	433_DN
Drug	Cephalosporanic acid, 7-amino [957-68-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A	RIPK1 LAMB3 BCR CACTIN PHLDB1 SAFB2 PLEC GCN1	1.30e-05	196	125	8	4826_DN
Disease	lysosomal storage disease (implicated_via_orthology)	TFEB TFE3 MITF	3.62e-05	16	121	3	DOID:3211 (implicated_via_orthology)
Disease	Pitt-Hopkins syndrome (implicated_via_orthology)	TCF3 TCF12	4.99e-05	3	121	2	DOID:0060488 (implicated_via_orthology)
Disease	liver cancer (is_implicated_in)	IKBKG CCND2	1.65e-04	5	121	2	DOID:3571 (is_implicated_in)
Disease	Orofaciodigital Syndromes	OFD1 SCLT1	2.47e-04	6	121	2	C0029294
Disease	MiT family translocation renal cell carcinoma	TFEB TFE3	3.46e-04	7	121	2	C4518356
Disease	systemic lupus erythematosus (implicated_via_orthology)	DEF6 C4A C4B	7.36e-04	43	121	3	DOID:9074 (implicated_via_orthology)
Disease	developmental disorder of mental health (implicated_via_orthology)	TCF3 TCF12 GIGYF2	1.08e-03	49	121	3	DOID:0060037 (implicated_via_orthology)
Disease	Necrosis	MYCN BCR TNNT2	1.51e-03	55	121	3	C0027540
Disease	platelet measurement	TCF12 DNM1L SVEP1 HABP4 PLEC CUX1	1.94e-03	315	121	6	EFO_0005036
Disease	Child Behaviour Checklist assessment	RIPK1 G3BP1	2.44e-03	18	121	2	EFO_0005661
Disease	renal cell carcinoma (is_implicated_in)	TFE3 C4A C4B	2.89e-03	69	121	3	DOID:4450 (is_implicated_in)
Disease	Lupus Erythematosus, Systemic	DEF6 C4A C4B	3.14e-03	71	121	3	C0024141
Disease	mean platelet volume	MICAL1 TCF12 DNM1L EPX TFAP4 SVEP1 NLRP6 HABP4 MAP3K11 PLEC CUX1	3.21e-03	1020	121	11	EFO_0004584
Disease	Precursor B-cell lymphoblastic leukemia	TCF3 BCR	3.33e-03	21	121	2	C1292769

Protein segments in the cluster

Peptide	Gene	Start	Entry
RERLAEARQRELQRQ	USH1C	301	Q9Y6N9
AVLRENARLQRDNER	AMOTL2	316	Q9Y2J4
NRDLRERLESANRRL	AMOTL2	391	Q9Y2J4
QERAVRRAAQVQRLE	CAVIN3	96	Q969G5
LNRRLQAENRELRDL	CCDC85B	66	Q15834
LQLFEGRRNRRRREA	C4B	1441	P0C0L5
NIEEQRRNRLARELP	DNM1L	511	O00429
SIRRLEQEVNQERFR	BCR	41	P11274
LRRRDRLQRQAFEEI	ATG16L1	21	Q676U5
RREVQRLRRRNQQLE	CBY1	71	Q9Y3M2
QLRRLQELNARRREE	ACTR5	301	Q9H9F9
RIAQQLERERALARQ	CHMP6	36	Q96FZ7
QRRAQLQERLEAARE	CFAP73	211	A6NFT4
LLERQQRRAEEARRR	CAMSAP3	906	Q9P1Y5
RRQSNLQEVLERERR	OFD1	896	O75665
AQQLEQIRRDIRDFR	ISYNA1	201	Q9NPH2
QALELADEARRRRQF	YOD1	296	Q5VVQ6
RDRNLLRDDRVLQNL	CCND2	16	P30279
LSAQEQEERRRRARQ	ANKRD13B	596	Q86YJ7
LQRRAQAAQEEQRRR	CFAP99	446	D6REC4
DERVQQLRRRISERA	CFAP99	571	D6REC4
ELERSRERRLQALQQ	CFAP99	686	D6REC4
REQEQRRLSQERDRL	PHLDB3	176	Q6NSJ2
RRLSQERDRLEGLRQ	PHLDB3	181	Q6NSJ2
EFERLQREREERRLQ	DNAJC11	106	Q9NVH1
QREREERRLQQRTNP	DNAJC11	111	Q9NVH1
NEFITRQRRRELSDR	HOXC12	236	P31275
TRQERRQRRQVVEAA	LAD1	91	O00515
RFRARNQELEAENRL	CUX1	511	Q13948
EQRRRRRQVQADALR	CCDC120	141	Q96HB5
QLEAQRAEAERLRQR	HOMER3	216	Q9NSC5
ILREAERRRQQQLQR	HABP4	41	Q5JVS0
RRRLELQLQEVQGRA	MYH14	1271	Q7Z406
LVDELRDRLFRQVRR	EPX	536	P11678
RRRQLELEVQQLRAG	EVPL	1401	Q92817
ANNARERLRVRDINE	TCF12	581	Q99081
RRELLQKHREQRREQ	EVC2	676	Q86UK5
LRDAIRQSNQILRER	IKBKG	61	Q9Y6K9
RRAEQLLQDARRARS	LAMB2	1581	P55268
LRLAERRQQRLREVQ	KIF26A	1781	Q9ULI4
VNQRDALIRFQEERR	MICAL1	1041	Q8TDZ2
AQLDREAQVRRRLQE	GCN1	836	Q92616
RRAFDGERLRLQQEI	JAKMIP1	141	Q96N16
QLNRRGEFIQEIRRQ	OAS1	91	P00973
QDVLRLRAETRQRAQ	PLEKHM3	431	Q6ZWE6
VEHDRRRRQFTVRLN	NATD1	21	Q8N6N6
LQQLRQAANVRERRR	PTF1A	161	Q7RTS3
RQEERLREQNLRALE	PRR7	41	Q8TB68
AFERQVRRQRLRAEV	ABT1	161	Q9ULW3
RVRRELERSHRQLEQ	CROCC	656	Q5TZA2
LREFLQELRSAQRER	CROCC	1511	Q5TZA2
ERIRREQQSARTRLQ	CXXC1	431	Q9P0U4
EANLRRQRRLVRSQV	HECTD1	1256	Q9ULT8
RQREQEIALRRQREE	GIGYF2	796	Q6Y7W6
QPAAVARRNERERNR	ASCL1	116	P50553
ERLQSRARERQQQRE	DDX51	36	Q8N8A6
FRENRRIRELLQDTL	CEP89	726	Q96ST8
RPQRDQRVREQRINI	G3BP1	296	Q13283
RRLEEQRLQALERRL	CRACD	246	Q6ZU35
RRLQAQAQAEERRRL	CRACD	321	Q6ZU35
VRAERNRAREEVRQL	CCDC102A	111	Q96A19
NRAREEVRQLRQRLD	CCDC102A	116	Q96A19
SFIEERRARENRLNQ	CCDC183	231	Q5T5S1
PQRQLDDEQERRIRL	CADPS2	71	Q86UW7
RNESRRLQEFLRFQD	CEMIP2	291	Q9UHN6
RRLRNHERREIQREI	BMP5	41	P22003
RLLQEEEERRRSQHR	DEF6	376	Q9H4E7
QQDEERRRQLRERAR	EHBP1	856	Q8NDI1
QLRDSRREAERLVRQ	LAMB3	741	Q13751
QQQSLQERLRLREER	CACTIN	136	Q8WUQ7
GFRRQQQEDRERLRA	EMILIN1	311	Q9Y6C2
TQTDRERERNTQRLR	FAM27E3	76	Q08E93
YRRRRQQRQAETEER	PPRC1	756	Q5VV67
RRAEEAQRQLEQERR	DBNL	196	Q9UJU6
AQRQLEQERRERELR	DBNL	201	Q9UJU6
ERELREAARREQRYQ	DBNL	211	Q9UJU6
RAAREQRSQAEQLRR	MAP3K11	426	Q16584
RDVAAQLQERRLQRL	NLRP6	91	P59044
LQLFEGRRNRRRREA	C4A	1441	P0C0L4
LRRLEEQFRRFQEVT	PTX4	41	Q96A99
FALEEAQRQRARERQ	OSBPL5	671	Q9H0X9
RRVQEIVRFTRQLQR	RPUSD4	71	Q96CM3
LLLAFLQRRQRRRQD	RXFP4	226	Q8TDU9
ERQRQEERQQAELRR	TSGA10IP	391	Q3SY00
EENQRVARRRRFPFV	RMDN3	131	Q96TC7
IRDRIQRRAEELRNT	ERVW-1	421	Q9UQF0
NLIERRRRFNINDRI	TFEB	241	P19484
NNLFRPRVREEANIR	GPRASP2	301	Q96D09
EFLNRLNRFLEEERR	PNMA3	101	Q9UL41
RIAREREELRRQQQQ	SLTM	701	Q9NWH9
REELRRQQQQLRYEQ	SLTM	706	Q9NWH9
QLRQEEKRQRVIRRH	MYCBP2	856	O75592
IRGIRNFNLENRAER	NDUFAF4	6	Q9P032
RYRRRVNRDDQEQDA	PPP1R26	1171	Q5T8A7
QNLVRDAIRRDRFEL	PGBD1	486	Q96JS3
QNVAYNREEERRRRV	RIPK1	401	Q13546
QAFRRRVRLLRELSE	SVEP1	66	Q4LDE5
ESNRDRRERLRQLAL	SF3A2	21	Q15428
EIARERLAFQRQRLE	SAFB	646	Q15424
RIHREREELRRQQEL	SAFB	686	Q15424
RAREDAERRNQLLQR	ARHGAP22	661	Q7Z5H3
QLRRENAALRRRLEA	ATF6B	366	Q99941
DLQVRQDVRNRTLRA	CHST14	101	Q8NCH0
VRRNLRASAREVRQE	SLC7A6OS	86	Q96CW6
ALLEQVARFREQLRR	TNIP2	66	Q8NFZ5
RLQQFFRRRNLELEE	TRAF3IP3	61	Q9Y228
RDQQAAEERRRDFLQ	TBXAS1	266	P24557
RRQQRLQEIERRRNT	GGCX	661	P38435
VQRRERALNRQVDVA	ZNF365	211	Q70YC5
NNVIIEQEERRRRSF	ZCCHC17	101	Q9NP64
VQRITRRLQQERRFL	TFPT	106	P0C1Z6
VREREQELQRQRRSV	MISP3	161	Q96FF7
HNLIERRRRFNINDR	MITF	316	O75030
AQALRQELERQRRLL	PBXIP1	391	Q96AQ6
ERRRNHNILERQRRN	MYCN	381	P04198
HNLIERRRRFNINDR	TFE3	351	P19532
RVANNARERLRVRDI	TCF3	551	P15923
RRQEELRRLEELRNQ	PSPC1	326	Q8WXF1
RRLENLENLLRNRNF	ZNF398	111	Q8TD17
RRAAEEAERQRQIQL	HGS	496	O14964
RAERAEQQRIRNERE	TNNT2	141	P45379
LRVEDRQDLNRQRIQ	TRPV6	671	Q9H1D0
QRLEEAAARRERRLQ	SPTBN4	756	Q9H254
HREREELRRQQEQLR	SAFB2	706	Q14151
ELRRQQEQLRYEQER	SAFB2	711	Q14151
DFLREQNRRLNEDFR	SCLT1	6	Q96NL6
ERRLRQAEVERARQV	PLEC	1686	Q15149
EYHRRQRQERLREQE	PHLDB1	591	Q86UU1
VRARRDFQRLQRRDS	VWA5B2	296	Q8N398
RAARQRRINRQLEAL	ZNHIT1	21	O43257
VRRRRDQEDALNQRY	TUT7	1366	Q5VYS8
QDRRQEEDQRRFEPR	TCHH	111	Q07283
ERREQQEERREQQLR	TCHH	326	Q07283
REQEERREQQLRREQ	TCHH	341	Q07283
RREQQLRREQEEERR	TCHH	346	Q07283
ERREQQLRREQQLRR	TCHH	371	Q07283
QLRREQQLRREQQLR	TCHH	376	Q07283
REQQLRREQQLRREQ	TCHH	391	Q07283
RREQQLRREQQLRRE	TCHH	396	Q07283
LRREQQLRREQQLRR	TCHH	401	Q07283
QLRREQQLRREQQLR	TCHH	406	Q07283
ERREQQLRREQEERR	TCHH	501	Q07283
ERLQQRLRSEQQLRR	TCHH	526	Q07283
RLRSEQQLRREQEER	TCHH	531	Q07283
QQLRREQEERREQLL	TCHH	536	Q07283
REQRERQLRAEERQQ	TCHH	791	Q07283
RQLRAEERQQREQRF	TCHH	796	Q07283
LQEDQERRRSQEQRR	TCHH	856	Q07283
RRRQEQERQYREEEQ	TCHH	921	Q07283
FLEEEQRLRRQERER	TCHH	1376	Q07283
EQQLRRQERDRKFRE	TCHH	1491	Q07283
EQQLRRQERDRKFRE	TCHH	1681	Q07283
RKFREEEQQLRRQER	TCHH	1691	Q07283
EQQLRRQERDRKFRE	TCHH	1761	Q07283
RLRQERDRQYRAEEQ	TCHH	1836	Q07283
NLRRNLRIVGERLFE	ZNF433	61	Q8N7K0
QRDQERRIRREIANS	TFAP4	41	Q01664
RRLENLENLLRNRNF	ZNF282	166	Q9UDV7
RRLENVENLLRNRNF	ZNF783	111	Q6ZMS7
EQFRRLLTQENRRVT	AGL	311	P35573
RLRGQEQALRFEQER	N4BP3	476	O15049
RRNQALEQELRALRE	N4BP3	516	O15049