Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal protein binding	KIF9 NEBL MAP4 MYO10 PLEKHG3 SBDS SPTA1 NUMA1 GBP2 LASP1 PLEKHH2 NEB RMDN2 UNC13A	6.99e-05	1099	77	14	GO:0008092
Domain	NEBU	NEBL LASP1 NEB	2.69e-07	4	77	3	SM00227
Domain	Nebulin	NEBL LASP1 NEB	2.69e-07	4	77	3	PF00880
Domain	Nebulin	NEBL LASP1 NEB	2.69e-07	4	77	3	IPR013998
Domain	NEBULIN	NEBL LASP1 NEB	2.69e-07	4	77	3	PS51216
Domain	Nebulin_repeat	NEBL LASP1 NEB	2.69e-07	4	77	3	IPR000900
Domain	zf-C2H2_6	ZNF567 ZNF569 ZNF728 ZNF790 ZNF479 ZNF749 ZNF554	3.12e-04	314	77	7	PF13912
Domain	SH3_1	NEBL SPTA1 LASP1 NEB TXK	5.83e-04	164	77	5	PF00018
Domain	MYTH4	MYO10 PLEKHH2	5.93e-04	9	77	2	PS51016
Domain	MyTH4_dom	MYO10 PLEKHH2	5.93e-04	9	77	2	IPR000857
Domain	MyTH4	MYO10 PLEKHH2	5.93e-04	9	77	2	PF00784
Domain	MyTH4	MYO10 PLEKHH2	5.93e-04	9	77	2	SM00139
Domain	KRAB	ZNF567 ZNF569 ZNF728 ZNF790 ZNF479 ZNF749 ZNF554	6.82e-04	358	77	7	PS50805
Domain	KRAB	ZNF567 ZNF569 ZNF728 ZNF790 ZNF479 ZNF749 ZNF554	6.82e-04	358	77	7	PF01352
Domain	KRAB	ZNF567 ZNF569 ZNF728 ZNF790 ZNF479 ZNF749 ZNF554	8.15e-04	369	77	7	SM00349
Domain	KRAB	ZNF567 ZNF569 ZNF728 ZNF790 ZNF479 ZNF749 ZNF554	8.28e-04	370	77	7	IPR001909
Domain	IBR	FBXO43 ARIH1	1.48e-03	14	77	2	SM00647
Domain	IBR	FBXO43 ARIH1	1.48e-03	14	77	2	PF01485
Domain	IBR_dom	FBXO43 ARIH1	1.70e-03	15	77	2	IPR002867
Domain	SH3	NEBL SPTA1 LASP1 NEB TXK	1.99e-03	216	77	5	SM00326
Domain	SH3	NEBL SPTA1 LASP1 NEB TXK	1.99e-03	216	77	5	PS50002
Domain	SH3_domain	NEBL SPTA1 LASP1 NEB TXK	2.15e-03	220	77	5	IPR001452
Domain	SH3_9	NEBL LASP1 NEB	4.11e-03	78	77	3	PF14604
Domain	-	ZNF567 ZNF146 ZNF569 ZNF728 ZNF790 ZNF479 ZNF749 ZNF554	6.78e-03	679	77	8	3.30.160.60
Domain	zf-C2H2	ZNF567 ZNF146 ZNF569 ZNF728 ZNF790 ZNF479 ZNF749 ZNF554	7.63e-03	693	77	8	PF00096
Domain	SNF2_N	ERCC6L2 SMARCA4	7.68e-03	32	77	2	IPR000330
Domain	SNF2_N	ERCC6L2 SMARCA4	7.68e-03	32	77	2	PF00176
Domain	Znf_C2H2/integrase_DNA-bd	ZNF567 ZNF146 ZNF569 ZNF728 ZNF790 ZNF479 ZNF749 ZNF554	7.70e-03	694	77	8	IPR013087
Pubmed	Analysis of the sperm flagellar axoneme using gene-modified mice.	KIF9 CFAP54 CFAP69	6.03e-07	8	78	3	32554934
Pubmed	Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions.	NEBL NEB	4.97e-06	2	78	2	19851499
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	FSIP2 ZNF567 ZNF146 PHF3 NUMA1 SMARCA4 SENP6 SNAPC4 USP48	8.97e-06	608	78	9	36089195
Pubmed	Zyxin interacts with the SH3 domains of the cytoskeletal proteins LIM-nebulette and Lasp-1.	NEBL LASP1	1.49e-05	3	78	2	15004028
Pubmed	Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling.	NEBL NEB	2.97e-05	4	78	2	23985323
Pubmed	The interferon-inducible p200 family of proteins: a perspective on their roles in cell cycle regulation and differentiation.	SPTA1 MNDA	4.94e-05	5	78	2	14757431
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	ZNF146 SETD1B SENP6 HSD17B10 TANC1 LASP1 CEP170B HDLBP	5.28e-05	588	78	8	38580884
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF567 ZNF569 ZNF728 ZNF749 ZNF554	5.61e-05	181	78	5	37372979
Pubmed	Actin binding of human LIM and SH3 protein is regulated by cGMP- and cAMP-dependent protein kinase phosphorylation on serine 146.	LASP1 PRKG2	7.40e-05	6	78	2	12571245
Pubmed	Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.	ARRB1 MAP4 SBDS ZNF790 NUMA1 LASP1	1.01e-04	330	78	6	21044950
Pubmed	N-myc regulates growth and fiber cell differentiation in lens development.	NUMA1 SMARCA4	1.04e-04	7	78	2	28716713
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	MAP4 PHF3 NUMA1 SMARCA4 USP48 HDLBP	1.04e-04	332	78	6	32786267
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TET2 FSIP2 VPS13D ZNF146 MAP4 PHF3 PLEKHG3 TANC1 CEP170B	1.33e-04	861	78	9	36931259
Pubmed	Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies.	NEBL NEB	1.38e-04	8	78	2	11309420
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	FAT4 ELMOD2 MAP4 ASXL3 SETBP1 HSD17B10 NEB	1.56e-04	513	78	7	25798074
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	MAP4 SPTA1 NUMA1 LASP1 KIAA1586	1.59e-04	226	78	5	31452512
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SETD1B MAP4 PLEKHG3 SBDS NIPSNAP1 NUMA1 SMARCA4 TANC1 LASP1 MTHFS HDLBP	2.11e-04	1353	78	11	29467282
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	YTHDF1 MAP4 PHF3 SBDS FER HSD17B10 LASP1 HDLBP	2.21e-04	724	78	8	36232890
Pubmed	Heritable Pulmonary Arterial Hypertension Overview	TET2 TBX4	2.21e-04	10	78	2	20301658
Pubmed	Analysis of HIV-1 Gag protein interactions via biotin ligase tagging.	SEMG1 MAP4 HDLBP	2.48e-04	54	78	3	25631074
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	YTHDF1 MAP4 PHF3 NUMA1 SMARCA4 SENP6 HSD17B10 ELL HDLBP	2.84e-04	954	78	9	36373674
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	VPS13D MAP4 GCC2 NUMA1 TANC1 LASP1 HDLBP	2.90e-04	568	78	7	37774976
Pubmed	Pellino-2 in nonimmune cells: novel interaction partners and intracellular localization.	MYO10 CEP170B	4.44e-04	14	78	2	34674267
Pubmed	Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network.	MYO10 NIPSNAP1 SMARCA4	4.90e-04	68	78	3	14676191
Pubmed	Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers.	NEBL NEB	5.84e-04	16	78	2	25987543
Pubmed	The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression.	MAP4 ARIH1 HDLBP	6.27e-04	74	78	3	35102251
Pubmed	Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR.	MAP4 NUMA1 SMARCA4	6.52e-04	75	78	3	29459360
Pubmed	Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease.	FAT4 NUMA1	6.61e-04	17	78	2	22153077
Pubmed	Localization of the mouse glucocorticoid receptor-interacting protein 1 gene (Grip1) to proximal chromosome 1 by linkage analysis.	SPTA1 HDLBP	6.61e-04	17	78	2	9250876
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	SETD1B ASXL3	9.19e-04	20	78	2	29785026
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	PHF3 NUMA1 HDLBP	9.71e-04	86	78	3	37253089
Pubmed	A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.	VPS13D LASP1 ARIH1	1.00e-03	87	78	3	37495603
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	TAOK3 MAP4 SBDS APOOL HSD17B10 LASP1 HDLBP	1.00e-03	701	78	7	30196744
Pubmed	Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.	PDE3A NMU	1.01e-03	21	78	2	22479202
Pubmed	An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.	GBP2 MNDA	1.01e-03	21	78	2	19158679
Pubmed	Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.	MYO10 ZNF790 PMFBP1	1.11e-03	90	78	3	15033168
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	MAP4 PHF3 SMARCA4 SENP6	1.25e-03	208	78	4	33230847
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MAP4 SPTA1 NIPSNAP1 SMARCA4 TANC1 MTHFS UNC13A CEP170B RHOT1 HDLBP	1.33e-03	1431	78	10	37142655
Pubmed	Interactome of the negative regulator of nuclear import BRCA1-binding protein 2.	NUMA1 ZNF479	1.56e-03	26	78	2	25820252
Pubmed	Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.	YTHDF1 FSIP2 NEBL ELMOD2 MAP4 LASP1	1.61e-03	558	78	6	35063084
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MAP4 PHF3 NUMA1 SMARCA4 SENP6 SNAPC4 HDLBP	1.77e-03	774	78	7	15302935
Pubmed	The human (PEDB) and mouse (mPEDB) Prostate Expression Databases.	SEMG1 APOOL NEB	1.77e-03	106	78	3	11752298
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ARRB1 MAP4 PLEKHG3 GCC2 SETBP1 DHRSX TANC1 ARIH1 CFAP69 CEP170B	1.79e-03	1489	78	10	28611215
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ARRB1 ZNF146 NEBL MAP4 PHF3 PLEKHG3 HSD17B10 TANC1 CEP170B HDLBP	1.86e-03	1497	78	10	31527615
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	PDE3A NUMA1 SMARCA4 NEB	1.93e-03	234	78	4	36243803
Pubmed	An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency.	NUMA1 SMARCA4	1.94e-03	29	78	2	19279220
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	MAP4 PHF3 SBDS NUMA1 SMARCA4 LASP1 ARIH1 USP48	1.97e-03	1014	78	8	32416067
Pubmed	Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development.	ASXL3 FBXO43	2.07e-03	30	78	2	38310234
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	MAP4 PLEKHG3 NIPSNAP1 NUMA1 SMARCA4 HSD17B10 LASP1 HDLBP	2.09e-03	1024	78	8	24711643
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	SEMG1 MAP4 SBDS NIPSNAP1 SMARCA4 LASP1 HDLBP	2.18e-03	803	78	7	36517590
Cytoband	19q13.12	ZNF567 ZNF569 ZNF790	2.59e-04	72	78	3	19q13.12
Cytoband	4q24	TET2 MTTP	1.54e-03	34	78	2	4q24
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF567 ZNF146 ZNF569 ZNF728 ZNF790 ZNF479 ZNF749 ZNF554	4.07e-04	718	46	8	28
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TBX4 NEBL MYO10 GPR153 SETBP1 PLEKHH2	1.18e-06	194	78	6	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF9 CFAP54 TBX4 NEB USP48	1.19e-05	169	78	5	16c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 PDE3A NEBL GPR153 SNX31	1.19e-05	169	78	5	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 PDE3A TANC1 PLEKHH2 TXK	1.84e-05	185	78	5	10da5c2a92bfb3248d3f6f94a0933996326cf590
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TAOK3 TBX4 NEBL MYO10 PLEKHH2	1.94e-05	187	78	5	a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	TBX4 MYO10 ASXL3 SETBP1 PLEKHH2	1.94e-05	187	78	5	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	TBX4 NEBL MYO10 TANC1 PLEKHH2	2.26e-05	193	78	5	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	FAT4 TBX4 MYO10 SETBP1 PLEKHH2	2.26e-05	193	78	5	acad568621ed677031797b8c2e34dafea798d681
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FAT4 TBX4 MYO10 TANC1 PLEKHH2	2.32e-05	194	78	5	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A ASXL3 SETBP1 PLEKHH2 CFAP69	2.32e-05	194	78	5	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TAOK3 TBX4 NEBL MYO10 PLEKHH2	2.37e-05	195	78	5	c5d2d9f12fd893331c9de261af30607d845d4f6a
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FAT4 TBX4 NEBL MYO10 PLEKHH2	2.37e-05	195	78	5	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	NEBL MYO10 SETBP1 TANC1 PLEKHH2	2.37e-05	195	78	5	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	PCW_05-06-Mesenchymal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FAT4 PDE3A TBX4 SETBP1 PLEKHH2	2.43e-05	196	78	5	dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FAT4 PDE3A TBX4 SETBP1 PLEKHH2	2.55e-05	198	78	5	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	FAT4 PDE3A TBX4 SETBP1 PLEKHH2	2.61e-05	199	78	5	4bac110c2b3609f6ee5d0e3275da0824a6240270
Drug	Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; PC3; HT_HG-U133A	MAP4 MYO10 PHF3 NUMA1 FER SENP6 SNAPC4	3.97e-06	192	77	7	4268_DN
Drug	Quercetine dihydrate [6151-25-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	VPS13D NEBL MAP4 PHF3 GBP2 NEB	3.34e-05	180	77	6	2859_DN
Drug	LY 294002; Down 200; 10uM; HL60; HT_HG-U133A	ARRB1 MAP4 NUMA1 SMARCA4 SENP6 SNAPC4	4.27e-05	188	77	6	6186_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	ARRB1 MAP4 PHF3 PLEKHG3 SNAPC4 PMFBP1	4.94e-05	193	77	6	2904_DN
Drug	Ipratropium bromide [22254-24-6]; Up 200; 9.8uM; HL60; HG-U133A	VPS13D MAP4 MYO10 PHF3 SMARCA4 PRKG2	5.08e-05	194	77	6	1769_UP
Drug	Benfotiamine [22457-89-2]; Down 200; 8.6uM; PC3; HT_HG-U133A	MAP4 MYO10 PHF3 NUMA1 FER SNAPC4	5.08e-05	194	77	6	4312_DN
Drug	rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A	SETD1B PHF3 PLEKHG3 GPR153 SENP6 CFAP69	5.38e-05	196	77	6	5230_UP
Drug	Benzocaine [94-09-7]; Up 200; 24.2uM; MCF7; HT_HG-U133A	VPS13D MYO10 PLEKHG3 NUMA1 FER PRKG2	5.38e-05	196	77	6	4808_UP
Drug	0316684-0000 [391209-55-5]; Up 200; 10uM; MCF7; HT_HG-U133A	NEBL MAP4 GPR153 SNAPC4 CTSK NMU	5.53e-05	197	77	6	7052_UP
Drug	Furazolidone [67-45-8]; Down 200; 17.8uM; HL60; HT_HG-U133A	NEBL MAP4 NUMA1 GBP2 NEB UNC13A	5.53e-05	197	77	6	3019_DN
Drug	Bicuculline (+) [485-49-4]; Down 200; 10.8uM; HL60; HT_HG-U133A	MAP4 PHF3 PLEKHG3 NEB ELL PMFBP1	5.69e-05	198	77	6	2139_DN
Drug	2-propylpentanoic acid; Down 200; 50uM; MCF7; HT_HG-U133A	VPS13D MYO10 GPR153 NUMA1 SNAPC4 CTSK	5.69e-05	198	77	6	5582_DN
Drug	Sulfapyridine [144-83-2]; Up 200; 16uM; MCF7; HT_HG-U133A	PHF3 GPR153 SETBP1 SNAPC4 CFAP69 UNC13A	5.69e-05	198	77	6	6799_UP
Drug	Methacycline hydrochloride [3963-95-9]; Up 200; 8.4uM; HL60; HT_HG-U133A	NEBL PHF3 PLEKHG3 GPR153 FER TXK	5.69e-05	198	77	6	2901_UP
Drug	Rolipram [61413-54-5]; Down 200; 14.6uM; HL60; HT_HG-U133A	VPS13D PHF3 NUMA1 CFAP69 ELL PMFBP1	5.69e-05	198	77	6	3072_DN
Drug	Trimethoprim [738-70-5]; Up 200; 13.8uM; HL60; HT_HG-U133A	MAP4 GPR153 NUMA1 USP48 CTSK PMFBP1	5.69e-05	198	77	6	2345_UP
Drug	PHA-00846566E [724718-26-7]; Up 200; 10uM; MCF7; HT_HG-U133A	NEBL MAP4 MYO10 PHF3 PLEKHG3 ELL	5.85e-05	199	77	6	7081_UP
Drug	Butamben [94-25-7]; Up 200; 20.6uM; MCF7; HT_HG-U133A	FAT4 VPS13D MAP4 NUMA1 GBP2 PMFBP1	5.85e-05	199	77	6	6093_UP
Drug	0317956-0000 [391210-11-0]; Up 200; 1uM; PC3; HT_HG-U133A	ARRB1 MAP4 MYO10 PHF3 PLEKHG3 NUMA1	5.85e-05	199	77	6	4334_UP
Disease	inositol measurement	MYO10 SETBP1 ELL	5.19e-06	14	73	3	EFO_0010504
Disease	Weight Gain	VPS13D MAP4 MYO10 SETBP1	1.22e-04	102	73	4	C0043094
Disease	smoking behavior, BMI-adjusted waist circumference	TBX4 FER PRKG2 HDLBP	2.43e-04	122	73	4	EFO_0004318, EFO_0007789
Disease	Small cell carcinoma of lung	TAOK3 FER SMARCA4	3.29e-04	54	73	3	C0149925
Disease	unipolar depression, bipolar disorder	FAT4 ASXL3 SETBP1 PMFBP1	6.16e-04	156	73	4	EFO_0003761, MONDO_0004985
Disease	MYELODYSPLASTIC SYNDROME	TET2 SBDS SETBP1	6.21e-04	67	73	3	C3463824
Disease	response to acetylsalicylate	KIF9 MAP4	7.08e-04	16	73	2	GO_1903492
Disease	spinal stenosis	PDE3A ELMOD2	8.02e-04	17	73	2	EFO_0007490
Disease	alkaline phosphatase measurement	TET2 KIF9 MAP4 GCC2 TMPRSS11E PLEKHH2 USP48 PMFBP1 HDLBP	8.78e-04	1015	73	9	EFO_0004533
Disease	apolipoprotein A 1 measurement	TET2 PDE3A TMPRSS11E FER MTTP ELL PMFBP1 HDLBP	1.16e-03	848	73	8	EFO_0004614
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	ASXL3 MTTP SMARCA4 PMFBP1	1.55e-03	200	73	4	EFO_0004611, EFO_0020945
Disease	Sezary Syndrome	TET2 SMARCA4	2.04e-03	27	73	2	C0036920

Protein segments in the cluster

Peptide	Gene	Start	Entry
TLNNEELKNHVYKKT	UNC13A	526	Q9UPW8
KTHRKQYNNKVDEIS	CTSK	31	P43235
QSTQIYLKKIAVHDT	CFAP54	556	Q96N23
IKKTNTNYSQEKHRC	ELL	581	P55199
LTYSKNKVLQKATHV	ELMOD2	51	Q8IZ81
YQKDIKTINHKIEDQ	ANKRD30B	461	Q9BXX2
HIQESSNYTTVKIKN	FAT4	4261	Q6V0I7
KHEKYTSQLQVSVKG	CEP170B	111	Q9Y4F5
NKDALEKTQTYLKVH	BBS10	476	Q8TAM1
VNVHVTNNTNKTVKK	ARRB1	216	P49407
VQSKLVSSFQQHTKK	ASXL3	141	Q9C0F0
RKHITYNNLSEKTSK	POLN	156	Q7Z5Q5
DSKVKLKYQHLITNS	ARIH1	251	Q9Y4X5
LSQKVIAHSEYQKSK	MTHFS	36	P49914
KVQIVSKKVSYSHIQ	MAP4	991	P27816
FHYSKTQKLGKSNVV	NMU	106	P48645
YTVEKKGNISSQLKH	IP6K2	161	Q9UHH9
EEHYVQKIVQKNRSK	LRRC53	536	A6NM62
KKTQDQISNIKYHEE	LASP1	111	Q14847
LSHSNIYQSITKDKK	FSIP2	4871	Q5CZC0
TVKVFNTVYSLVKHN	KIAA1586	246	Q9HCI6
VYAVNNKHSIDKVTS	RHOT1	81	Q8IXI2
VTYQAHQDKVIKIKA	MTTP	176	P55157
SYAISAANHVKAKKQ	PDE3A	496	Q14432
VNYRLSNAKKQAVHT	GPR153	116	Q6NV75
VFTYKQSTITHQKVT	MYO10	41	Q9HD67
EQKEKSYQEHVKQLT	GBP2	516	P32456
SISFYNAKVKIEQKH	KIF9	761	Q9HAQ2
VASKTYNLKKGQTHT	HSD17B10	96	Q99714
KKHIVDTKQQEHVYS	PRKG2	486	Q13237
DNKQTVQLTTEKHTY	PLEKHH2	761	Q8IVE3
HLSSKQEEYVKVAKT	FBXO43	616	Q4G163
HANKAKQNVAKYQST	GJA9	256	P57773
DKQQVKKSYIGVHQQ	FER	106	P16591
HYTTKQVITKKSGVV	FER	531	P16591
ESYKVRVHNVLKQQK	GCC2	1321	Q8IWJ2
NEKETKSLHVTYNQK	DHRSX	296	Q8N5I4
NQKKKKVYHTNQTTF	ERCC6L2	1211	Q5T890
QKVYAKIQATHKQRE	CFAP69	816	A5D8W1
KEKTINQTIGNVVYH	SLC15A4	431	Q8N697
HYSVKTNKSTKQQAL	SBDS	141	Q9Y3A5
KAKTHYDAKKQQNQE	NUMA1	1616	Q14980
AKVTAKKVYATSQQI	APOOL	161	Q6UXV4
KAFSQKQYVIKHQNT	ZNF146	51	Q15072
SVHKKNTIYEIQDNT	MNDA	331	P41218
KETSNLYKIQFHNVK	NIPSNAP1	66	Q9BPW8
QKEKHYLQTTITKEA	PMFBP1	716	Q8TBY8
TVTHYKHSKQQYSIQ	PLEKHG3	361	A1L390
KHSKQQYSIQAKTVE	PLEKHG3	366	A1L390
KSQQYDLNALHKTTK	SEMG1	81	P04279
KIQKLTKAVATYHAN	SMARCA4	496	P51532
STNTQEKKHYANIGK	RMDN2	231	Q96LZ7
KTVSHLYQESISKQQ	TANC1	1821	Q9C0D5
TKQYKALKNHQLEVT	TAOK3	731	Q9H2K8
SQKKIVIYSKQHINV	SETD1B	1921	Q9UPS6
EQSKSKKYHIQQSQQ	SNX31	396	Q8N9S9
VKSQVIKFSQQKHGV	TMPRSS11E	101	Q9UL52
QEKYSRSVVSINHKK	ZNF567	91	Q8N184
SSKVFKYNSSLIKHQ	ZNF749	756	O43361
HKKGYNKLNQSLTTT	ZNF728	126	P0DKX0
AAKYEVIHSKTKVNV	PHF3	511	Q92576
SVKYSVKKINHTASE	SENP6	856	Q9GZR1
YQKHQSLEAEVQTKS	SPTA1	91	P02549
TTQNKIFQTHKYVKV	ZNF479	151	Q96JC4
TEAAIKHYQIKKNDS	TXK	196	P42681
KAFSQKQNFITHQKV	ZNF569	501	Q5MCW4
SEVIQYQTVHTVKKT	ZNF790	211	Q6PG37
KLEYLHQKQSKVSSE	SNAPC4	211	Q5SXM2
HTELSKLIKSYQKSQ	SPZ1	261	Q9BXG8
SVTSYQNHKITQLKI	TBX4	226	P57082
TTIAVEVKKSQHKYV	HDLBP	296	Q00341
NYTKILSTKKNLDHV	SETBP1	1416	Q9Y6X0
TQKTTQLEHKSQMYQ	TET2	621	Q6N021
QATIYVHKVVDNKKV	USP48	861	Q86UV5
AKQVLKIISSYKHTT	YTHDF1	516	Q9BYJ9
HGKVYVQVTKKAVST	VPS13D	4316	Q5THJ4
QKTHSSQKTYKIIDC	ZNF554	511	Q86TJ5
AVNEHLNQKKYATQK	LRRIQ3	456	A6PVS8
EVTQLQSEVAYKQKH	NEBL	116	O76041
KTVSNLVSENKYKDH	NEB	5641	P20929
HAQQVKNLSSQKKYK	NEB	6071	P20929