Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionserine-type peptidase activity

TMPRSS9 RELN PAMR1 PRSS55 TYSND1 CTSA RHBDD3 MST1L CTSH

5.51e-062071239GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

TMPRSS9 RELN PAMR1 PRSS55 TYSND1 CTSA RHBDD3 MST1L CTSH

6.69e-062121239GO:0017171
GeneOntologyMolecularFunctioncomplement receptor activity

CR1 CR2 C5AR1

7.90e-05141233GO:0004875
GeneOntologyMolecularFunctionserine-type endopeptidase activity

TMPRSS9 PAMR1 PRSS55 TYSND1 RHBDD3 MST1L CTSH

1.77e-041901237GO:0004252
DomainEGF_1

RELN PAMR1 NTN3 LAMC3 SSPOP NTN4 HMCN2 CELSR2 NOTCH3 CRB2

6.81e-0625512210PS00022
DomainGrowth_fac_rcpt_

NTN3 LAMC3 NTN4 IGF1R HMCN2 CELSR2 ELAPOR1 NOTCH3

8.52e-061561228IPR009030
DomainEGF_LAM_2

NTN3 LAMC3 NTN4 CELSR2

4.16e-05301224PS50027
DomainEGF_LAM_1

NTN3 LAMC3 NTN4 CELSR2

4.16e-05301224PS01248
DomainEGF-like_CS

RELN PAMR1 NTN3 LAMC3 NTN4 HMCN2 CELSR2 NOTCH3 CRB2

5.46e-052611229IPR013032
DomainEGF_2

RELN PAMR1 NTN3 LAMC3 SSPOP HMCN2 CELSR2 NOTCH3 CRB2

6.14e-052651229PS01186
DomainEGF_Lam

NTN3 LAMC3 NTN4 CELSR2

7.76e-05351224SM00180
DomainLaminin_EGF

NTN3 LAMC3 NTN4 CELSR2

7.76e-05351224PF00053
DomainLaminin_EGF

NTN3 LAMC3 NTN4 CELSR2

1.08e-04381224IPR002049
DomainLaminin_N

NTN3 LAMC3 NTN4

1.43e-04161223IPR008211
DomainLamNT

NTN3 LAMC3 NTN4

1.43e-04161223SM00136
DomainLAMININ_NTER

NTN3 LAMC3 NTN4

1.43e-04161223PS51117
DomainLaminin_N

NTN3 LAMC3 NTN4

1.43e-04161223PF00055
DomainSushi

PAMR1 CR1 CR2 CSMD3

3.68e-04521224PF00084
DomainCCP

PAMR1 CR1 CR2 CSMD3

4.26e-04541224SM00032
DomainSUSHI

PAMR1 CR1 CR2 CSMD3

4.90e-04561224PS50923
DomainSushi_SCR_CCP_dom

PAMR1 CR1 CR2 CSMD3

5.24e-04571224IPR000436
DomainHormR

VIPR1 ADGRB2 CELSR2

5.63e-04251223SM00008
DomainhEGF

CELSR2 NOTCH3 CRB2

7.91e-04281223PF12661
DomainHRM

VIPR1 ADGRB2 CELSR2

7.91e-04281223PF02793
DomainEGF_3

RELN PAMR1 SSPOP HMCN2 CELSR2 NOTCH3 CRB2

8.98e-042351227PS50026
DomainTryp_SPc

TMPRSS9 PAMR1 PRSS55 TYSND1 MST1L

1.02e-031171225SM00020
DomainTrypsin_dom

TMPRSS9 PAMR1 PRSS55 TYSND1 MST1L

1.19e-031211225IPR001254
DomainTrypsin

TMPRSS9 PAMR1 PRSS55 TYSND1 MST1L

1.19e-031211225PF00089
DomainEGF_CA

PAMR1 HMCN2 CELSR2 NOTCH3 CRB2

1.24e-031221225SM00179
DomainEGF-like_dom

RELN PAMR1 LAMC3 HMCN2 CELSR2 NOTCH3 CRB2

1.26e-032491227IPR000742
DomainPeptidase_S1_PA

TMPRSS9 PAMR1 PRSS55 TYSND1 MST1L

1.28e-031231225IPR009003
DomainEGF-like_Ca-bd_dom

PAMR1 HMCN2 CELSR2 NOTCH3 CRB2

1.33e-031241225IPR001881
DomainFormyl_rcpt-rel

C5AR1 PTGDR2

1.84e-03101222IPR000826
DomainGAIN_dom_N

ADGRB2 CELSR2

2.24e-03111222IPR032471
DomainZnF_BED

ZBED4 ZNF333

2.24e-03111222SM00614
DomainGAIN

ADGRB2 CELSR2

2.24e-03111222PF16489
DomainGPCR_2_extracellular_dom

VIPR1 ADGRB2 CELSR2

2.25e-03401223IPR001879
DomainG_PROTEIN_RECEP_F2_1

VIPR1 ADGRB2 CELSR2

2.25e-03401223PS00649
DomainG_PROTEIN_RECEP_F2_3

VIPR1 ADGRB2 CELSR2

2.25e-03401223PS50227
DomainZnf_BED

ZBED4 ZNF333

2.68e-03121222IPR003656
DomainGalactose-bd-like

NTN3 LAMC3 SSPOP NTN4

3.36e-03941224IPR008979
DomainEamA

SLC35G6 SLC35E4

3.66e-03141222PF00892
DomainEamA_dom

SLC35G6 SLC35E4

3.66e-03141222IPR000620
DomainASX_HYDROXYL

HMCN2 CELSR2 NOTCH3 CRB2

4.19e-031001224PS00010
Domain7tm_2

VIPR1 ADGRB2 CELSR2

4.26e-03501223PF00002
DomainG_PROTEIN_RECEP_F2_2

VIPR1 ADGRB2 CELSR2

4.26e-03501223PS00650
DomainEGF

RELN PAMR1 LAMC3 CELSR2 NOTCH3 CRB2

4.48e-032351226SM00181
DomainCUB

PAMR1 ADAMTS13 CSMD3

5.02e-03531223PS01180
DomainEGF-type_Asp/Asn_hydroxyl_site

HMCN2 CELSR2 NOTCH3 CRB2

5.16e-031061224IPR000152
DomainC345C

NTN3 NTN4

5.40e-03171222SM00643
DomainCUB_dom

PAMR1 ADAMTS13 CSMD3

6.16e-03571223IPR000859
DomainPeptidase_S1A

TMPRSS9 PAMR1 PRSS55 MST1L

6.46e-031131224IPR001314
PathwayKEGG_HEMATOPOIETIC_CELL_LINEAGE

ITGA2B CR1 CR2 CSF1 CD19 GP1BB

1.20e-0587836M6856
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

SEMA6B FNDC3B AMN PAMR1 ESPNL PRSS55 IL20RA ADAMTS13 SLC44A4 TMEM130 VKORC1 HHIPL2 ELAPOR1 C1orf159 TMCO3 BTNL9 ECE2

1.53e-079851291712975309
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

SEMA6B FNDC3B AUH MRPL12 RPN1 STING1 IDH2 TARS2 CR1 CTSA HPDL DDOST IARS2 VKORC1 CELSR2 PRDX3 DLAT POLDIP2 ADPGK

1.78e-0614511291930550785
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 SEMA6B DPH2 TBC1D9B LRFN1 UBE4B ADGRB2 LAMC3 ZFPM1 THADA IGF1R CELSR2 ZBED4 SLC45A3 FLCN HR

3.58e-0611051291635748872
Pubmed

A mouse knockout library for secreted and transmembrane proteins.

FNDC3B PAMR1 ITGA2B SLC44A4 TMEM130 HHIPL2 ELAPOR1 C1orf159 TMCO3 BTNL9

9.00e-064601291020562862
Pubmed

Complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) cooperate in the binding of hydrolyzed complement factor 3 (C3i) to human B lymphocytes.

CR1 CR2

1.37e-052129214635039
Pubmed

The role of complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) in promoting C3 fragment deposition and membrane attack complex formation on normal peripheral human B cells.

CR1 CR2

1.37e-052129211981823
Pubmed

Uncoupling CD21 and CD19 of the B-cell coreceptor.

CR2 CD19

1.37e-052129219706534
Pubmed

EBV attachment stimulates FHOS/FHOD1 redistribution and co-aggregation with CD21: formin interactions with the cytoplasmic domain of human CD21.

CR2 FHOD1

1.37e-052129215138285
Pubmed

Molecular interactions of complement receptors on B lymphocytes: a CR1/CR2 complex distinct from the CR2/CD19 complex.

CR1 CR2

1.37e-05212921708808
Pubmed

A role for CD21/CD35 and CD19 in responses to acute septic peritonitis: a potential mechanism for mast cell activation.

CR2 CD19

1.37e-052129211120817
Pubmed

Comparative functional evolution of human and mouse CR1 and CR2.

CR1 CR2

1.37e-052129218713965
Pubmed

STING regulates BCR signaling in normal and malignant B cells.

STING1 CD19

1.37e-052129232999453
Pubmed

Complement receptor type 1 and 2 (CR1 and CR2) gene polymorphisms and plasma protein levels are associated with the Dengue disease severity.

CR1 CR2

1.37e-052129237833411
Pubmed

Intersection of the complement and immune systems: a signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19.

CR2 CD19

1.37e-05212921702139
Pubmed

[THE COMBINATION OF EXPRESSION OF MARKERS CR1 AND CR2 (CD35/CD21) IN DIAGNOSTIC OF B-CELL LYMPHOPROLIFERATIVE DISEASES].

CR1 CR2

1.37e-052129226189291
Pubmed

Malaria inhibits surface expression of complement receptor 1 in monocytes/macrophages, causing decreased immune complex internalization.

CR1 CR2

1.37e-052129223440418
Pubmed

Coligation of the B cell receptor with complement receptor type 2 (CR2/CD21) using its natural ligand C3dg: activation without engagement of an inhibitory signaling pathway.

CR2 CD19

1.37e-052129215749857
Pubmed

Dynamic regulation of B cell complement signaling is integral to germinal center responses.

CR2 CD19 C5AR1

2.69e-0516129334031614
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

VIPR1 CR1 CR2 IGF1R NOTCH3

3.87e-05101129523382219
Pubmed

Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signaling.

ITGA2B GP1BB

4.09e-053129212860973
Pubmed

CD19 can regulate B lymphocyte signal transduction independent of complement activation.

CR2 CD19

4.09e-053129211544305
Pubmed

Interleukin-2 induces N-glycosylation in T-cells: characterization of human lymphocyte oligosaccharyltransferase.

RPN1 DDOST

4.09e-05312929642163
Pubmed

Processing of pulmonary surfactant protein B by napsin and cathepsin H.

SFTPB CTSH

4.09e-053129214766755
Pubmed

Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes.

CR1 CR2

4.09e-05312927690834
Pubmed

A critical role for complement C3d and the B cell coreceptor (CD19/CD21) complex in the initiation of inflammatory arthritis.

CR2 CD19

4.09e-053129216210644
Pubmed

Role of complement-binding CD21/CD19/CD81 in enhancing human B cell protection from Fas-mediated apoptosis.

CR2 CD19

4.09e-053129214607925
Pubmed

A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32.

CR1 CR2

4.09e-05312923782802
Pubmed

CD19 is essential for B cell activation by promoting B cell receptor-antigen microcluster formation in response to membrane-bound ligand.

CR2 CD19

4.09e-053129218059271
Pubmed

Murine complement receptor gene family. II. Identification and characterization of the murine homolog (Cr2) to human CR2 and its molecular linkage to Crry.

CR1 CR2

4.09e-05312922528587
Pubmed

Impaired TLR9 responses in B cells from patients with systemic lupus erythematosus.

CR2 CD19

4.09e-053129229515028
Pubmed

Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein.

CR1 CR2

4.09e-05312927528766
Pubmed

Complement component C3d-antigen complexes can either augment or inhibit B lymphocyte activation and humoral immunity in mice depending on the degree of CD21/CD19 complex engagement.

CR2 CD19

4.09e-053129216339538
Pubmed

THADA fusion is a mechanism of IGF2BP3 activation and IGF1R signaling in thyroid cancer.

THADA IGF1R

4.09e-053129228193878
Pubmed

The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1.

CR1 CR2

4.09e-05312922139460
Pubmed

Hyperinsulinemic hypoglycemia with nesidioblastosis: histologic features and growth factor expression.

TGFBR3 IGF1R

4.09e-053129218931647
Pubmed

Family-based genome scan for age at onset of late-onset Alzheimer's disease in whole exome sequencing data.

LAMC3 NTN4

4.09e-053129226394601
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

RPN1 LAMC3 CTSA ATF6B DDOST TFPI THADA IGF1R CELSR2 FHOD1 PRDX3 FLCN TMCO3 ADPGK NOTCH3

4.11e-0512011291535696571
Pubmed

Mitotic Phosphorylation of TREX1 C Terminus Disrupts TREX1 Regulation of the Oligosaccharyltransferase Complex.

RPN1 DDOST

8.15e-054129228297665
Pubmed

Binding of netrin-4 to laminin short arms regulates basement membrane assembly.

LAMC3 NTN4

8.15e-054129217588941
Pubmed

Complement C3b contributes to Escherichia coli-induced platelet aggregation in human whole blood.

ITGA2B CR1

8.15e-054129236591264
Pubmed

Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection.

CR1 CR2

8.15e-054129216127466
Pubmed

Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity.

CR2 CD19

8.15e-054129232142650
Pubmed

Malectin forms a complex with ribophorin I for enhanced association with misfolded glycoproteins.

RPN1 DDOST

8.15e-054129222988243
Pubmed

The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules.

CR2 CD19

8.15e-05412921383329
Pubmed

Loss of Reelin protects mice against arterial thrombosis by impairing integrin activation and thrombus formation under high shear conditions.

RELN GP1BB

8.15e-054129228943410
Pubmed

CD19 signaling pathways play a major role for murine AIDS induction and progression.

CR2 CD19

8.15e-054129212421939
Pubmed

Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma.

CR1 CR2

8.15e-054129230217731
Pubmed

The selection of marginal zone B cells differs from that of B-1a cells.

CR2 CD19

8.15e-054129214662849
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

AUH MRPL12 IDH2 TARS2 HPDL IARS2 CLPB APEX2 PRDX3 LYPLA1 DLAT PLD6 POLDIP2 AFG1L

8.66e-0511361291434800366
Pubmed

Complement-dependent P-selectin expression and injury following ischemic stroke.

CR1 CR2

1.36e-045129217082645
Pubmed

Protective T cell-independent antiviral antibody responses are dependent on complement.

CR2 CD19

1.36e-045129210523614
Pubmed

Modified N-methyl-D-aspartate receptor subunit expression emerges in reeler Purkinje cells after accomplishment of the adult wild-type expression.

RELN GRIN2C

1.36e-04512929004271
Pubmed

Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3.

ITGA2B GP1BB

1.36e-045129211812775
Pubmed

Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation.

CR1 CR2

1.36e-045129220962256
Pubmed

A single transcription factor is sufficient to induce and maintain secretory cell architecture.

ELAPOR1 MST1L

1.36e-045129228174210
Pubmed

Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation.

STING1 DDOST

1.36e-045129226320659
Pubmed

The level of IgE produced by a B cell is regulated by norepinephrine in a p38 MAPK- and CD23-dependent manner.

CR2 CD19

1.36e-045129216920928
Pubmed

Expression pattern and neurotrophic role of the c-fms proto-oncogene M-CSF receptor in rodent Purkinje cells.

RELN CSF1

1.36e-04512929852586
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

AMN ADGRB2 ADAMTS13 SSPOP

1.79e-0475129420637190
Pubmed

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

AUH IDH2 CTSA IARS2 APEX2 PRDX3 LYPLA1 DLAT POLDIP2

1.99e-04542129914651853
Pubmed

Simultaneous genotyping of human platelet antigen-1 to 17w by polymerase chain reaction sequence-based typing.

ITGA2B GP1BB

2.03e-046129219570064
Pubmed

Association of polymorphisms of IGF1R and genes in the transforming growth factor- beta /bone morphogenetic protein pathway with bacteremia in sickle cell anemia.

TGFBR3 IGF1R

2.03e-046129216886151
Pubmed

Delineating the roles of the GPIIb/IIIa and GP-Ib-IX-V platelet receptors in mediating platelet adhesion to adsorbed fibrinogen and albumin.

ITGA2B GP1BB

2.03e-046129221529934
Pubmed

CD21/35 promotes protective immunity to Streptococcus pneumoniae through a complement-independent but CD19-dependent pathway that regulates PD-1 expression.

CR2 CD19

2.03e-046129219710450
Pubmed

Distinct roles for C3a and C5a in complement-induced tubulointerstitial injury.

CR1 C5AR1

2.03e-046129221677637
Pubmed

Follicular shuttling of marginal zone B cells facilitates antigen transport.

CR2 CD19

2.03e-046129218037889
Pubmed

The allele frequencies of HPA 1-16 determined by PCR-SSP in Chinese Cantonese donors.

ITGA2B GP1BB

2.03e-046129220667040
Pubmed

CD19 is linked to the integrin-associated tetraspans CD9, CD81, and CD82.

CR2 CD19

2.03e-04612929804823
Pubmed

Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.

CR1 CR2 C5AR1

2.08e-0431129319344414
Pubmed

Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.

RELN AUH MRPL12 IDH2 PRDX3 LYPLA1 DLAT

2.46e-04331129729199018
Pubmed

Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome.

RPN1 DDOST VKORC1 PRDX3

2.77e-0484129431616248
Pubmed

Cutting Edge: Neutrophil Complement Receptor Signaling Is Required for BAFF-Dependent Humoral Responses in Mice.

CR2 C5AR1

2.83e-047129236454023
Pubmed

Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability.

MRPL12 RPN1 IDH2 DLAT PTGDR2

3.37e-04160129523798571
Pubmed

Activation of Epstein-Barr virus/C3d receptor (gp140, CR2, CD21) on human B lymphoma cell surface triggers Cbl tyrosine phosphorylation, its association with p85 subunit, Crk-L and Syk and its dissociation with Vav.

CR2 CD19

3.77e-048129216289966
Pubmed

The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands.

CSF1 C5AR1

3.77e-048129217114491
Pubmed

Genetic organization of complement receptor-related genes in the mouse.

CR1 CR2

3.77e-04812922564419
Pubmed

Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse.

IGF1R HR

3.77e-048129216461637
Pubmed

A CD9, alphaIIbbeta3, integrin-associated protein, and GPIb/V/IX complex on the surface of human platelets is influenced by alphaIIbbeta3 conformational states.

ITGA2B GP1BB

3.77e-048129210429193
Pubmed

Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons.

RELN LMO4 DMRTA1

4.46e-0440129326671461
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

RPN1 IDH2 TARS2 DDOST IARS2 CLPB PRDX3 POLDIP2 ADPGK

4.54e-04607129939147351
Pubmed

Marginal zone SIGN-R1+ macrophages are essential for the maturation of germinal center B cells in the spleen.

CR2 CD19

4.83e-049129232424104
Pubmed

The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals.

CR2 CD19

4.83e-049129219494269
Pubmed

Platelet alpha-granules.

ITGA2B GP1BB

4.83e-04912928467233
Pubmed

STING-induced regulatory B cells compromise NK function in cancer immunity.

STING1 CD19

4.83e-049129236198789
Pubmed

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes.

AUH MRPL12 IDH2 TARS2 IARS2 PRDX3 DLAT

5.80e-04382129729222160
Pubmed

The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons.

RELN TGFBR3 IGF1R

5.91e-0444129327224923
Pubmed

Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo.

CR2 CD19

6.02e-0410129215909309
Pubmed

Definitive Hematopoiesis in the Yolk Sac Emerges from Wnt-Responsive Hemogenic Endothelium Independently of Circulation and Arterial Identity.

ITGA2B GP1BB

6.02e-0410129226418893
Pubmed

Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition.

IDH2 DDOST IARS2 PRDX3 DLAT

6.05e-04182129536225252
Pubmed

Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos.

ITGA2B GP1BB

7.35e-0411129220876651
Pubmed

Mapping of recombinant retrovirus integration sites that cause expression of the viral genome in murine embryonal carcinoma cells.

CR1 CR2

7.35e-041112921543915
Pubmed

Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis.

NTN3 NTN4

7.35e-0411129215186747
Pubmed

Dmrt genes participate in the development of Cajal-Retzius cells derived from the cortical hem in the telencephalon.

RELN DMRTA1

7.35e-0411129232012381
Pubmed

Cryo-electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B.

RPN1 DDOST

7.35e-0411129231831667
Pubmed

Loci at chromosomes 13, 19 and 20 influence age at natural menopause.

TMEM150B SLC44A4

7.35e-0411129219448619
Pubmed

FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons.

NTN3 NTN4

8.79e-0412129221673655
Pubmed

Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits.

RPN1 DDOST

8.79e-0412129215835887
Pubmed

Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development.

CSF1 CELSR2

8.79e-0412129211891983
Pubmed

Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus.

CR2 TGFBR3 CD19

1.02e-0353129318174230
Pubmed

Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study.

TARS2 IARS2

1.04e-0313129219209188
InteractionCR2 interactions

CR1 CR2 CD19 FHOD1

2.27e-06161234int:CR2
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PAMR1 CR1 CR2 CSMD3

1.01e-04577741179
GeneFamilyNetrins

NTN3 NTN4

2.66e-046772661
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ITGA2B CR1 CR2 IGF1R CD19 C5AR1 PTGDR2 GP1BB

2.68e-04394778471
GeneFamilyComplement system|Sushi domain containing

CR1 CR2 C5AR1

4.79e-0436773492
GeneFamilyOligosaccharyltransferase complex subunits

RPN1 DDOST

1.15e-0312772445
GeneFamilyCathepsins

CTSA CTSH

1.81e-0315772470
GeneFamilyFibronectin type III domain containing

FNDC3B LRFN1 IGF1R PTPRH

4.84e-03160774555
ToppCellHealthy-B_cell|Healthy / disease group, cell group and cell class

FFAR1 ADGRB2 CR2 TGFBR3 ADAD2 TMEM130 CD19 BTNL9

1.60e-0815312987f82cd61b3f1ebaee3e4bbf68ba858a67c2065e7
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ITGA2B CR1 B3GNT8 SLC45A3 TMEM44 C5AR1 TTLL10 PTGDR2

4.56e-081751298ba1befc4e5f0167452f9ceace39377d16136dfa9
ToppCellSigmoid-T_cell-Tcm|T_cell / Region, Cell class and subclass

VIPR1 NWD1 AMN PASK PTPRH ELAPOR1 DLAT PLD6

1.23e-071991298acdf95f4d58df47690f4ae254245bc618f9ac07e
ToppCellClub-club-2|World / Class top

VIPR1 ESPNL IDH2 SLC44A4 SLC45A3 LRRC26 ELAPOR1

5.62e-07166129756f11efb6b686b3ee2c34a051f626e3d761b5112
ToppCellproximal-Hematologic-Platelet/Megakaryocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AMN PBLD ADAMTS13 TMEM130 PTPRH CLPB TIGD5

1.49e-061921297522d1bb15edf1d6006b80289bd3baadb99584ae8
ToppCellproximal-3-Hematologic-Platelet/Megakaryocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AMN PBLD ADAMTS13 TMEM130 PTPRH CLPB TIGD5

1.49e-061921297f5f83dec37dff32a0c471cb05d23d13b0b0ad0c9
ToppCellproximal-Hematologic-Platelet/Megakaryocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AMN PBLD ADAMTS13 TMEM130 PTPRH CLPB TIGD5

1.49e-06192129757899a905ca3e336bb7f31edc6418a2546b9891a
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B-Memory_B_cells|lymph-node_spleen / Manually curated celltypes from each tissue

CR1 CR2 WDFY4 CD19 SLC45A3 CTSH BTNL9

1.65e-0619512978b307079cee67fc1df55277d0cab21ea4b97e552
ToppCellEpithelial-Epithelial-B_(AT1-AT2-progenitors)|Epithelial / shred on cell class and cell subclass (v4)

SEMA6B SFTPB TARS2 NTN4 PLD6 CTSH

5.86e-061541296770712806e26f73456fb77a81aa4ef8ec78a21ea
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Sc17a7.Calb1-Lpl_(Layer_2/3)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ESPNL ADAMTS13 TMEM235 WDFY4 HHIPL2

7.22e-06921295dfe63bb979f0382163955b32909ffab1de37685a
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SFTPB ZFPM1 TFPI B3GNT8 NTN4 CTSH

8.41e-061641296b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SFTPB ZFPM1 TFPI B3GNT8 NTN4 CTSH

8.41e-0616412963aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF135 CR2 ATF6B B3GNT8 CD19 ZC3H12D

8.41e-061641296875d922eec7e3df0998ddf0c8c4dee2dcd5b23ca
ToppCelldroplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGA2B IGF1R CSF1 SLC45A3 HSD17B1 BTNL9

9.65e-0616812960e99ecd94ab8e5372e30433d7d0aa76b4d54257a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGA2B IGF1R CSF1 SLC45A3 HSD17B1 BTNL9

9.65e-06168129634722e14f28313f2e4644b3c1861ef12958cee9f
ToppCellAdult-Immune-B_cell-D175|Adult / Lineage, Cell type, age group and donor

FFAR1 ZFPM1 CR2 WDFY4 CD19 ZC3H12D

1.07e-051711296355a246f3395900342d400f6f7c6640cba0d4d5d
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GRIN2C CTSA B3GNT8 TMEM130 SLC35E4 TTLL10

1.18e-051741296e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

GRIN2C CTSA B3GNT8 TMEM130 SLC35E4 TTLL10

1.26e-051761296bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D9B IL20RA IDH2 SLC45A3 TMEM44 NOTCH3

1.26e-051761296d43d9e86c4d4fa1e88fbf2b899ac7143717aac90
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TMEM210 CD19 SLC45A3 DMRTA1 PTGDR2

1.31e-05104129530b2f6f6612ea45c92f0d466e301d85291a2ee70
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TMEM210 CD19 SLC45A3 DMRTA1 PTGDR2

1.31e-051041295a0e03cc97d453050c6b7e6e290ef0babc7bc1276
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TMEM210 CD19 SLC45A3 DMRTA1 PTGDR2

1.31e-0510412953cc15f0abdf1f4304af9152911a1f3aab3bc0925
ToppCellMild-CD4+_T|Mild / Disease group and Cell class

VIPR1 ATG9B STING1 CR1 PASK CTSH

1.67e-051851296c28ecb63146de1b02418e5a4fad0ae7c2b66a41d
ToppCellClub|World / Class top

SFTPB IDH2 SLC44A4 LRRC26 ELAPOR1 CTSH

1.67e-051851296c3caf789e622ed515d143dc594158d52fdcffaef
ToppCellHSPCs-Eo/Baso_prog.|HSPCs / Lineage and Cell class

ITGA2B LMO4 IGF1R CSF1 SLC45A3 ELAPOR1

1.67e-0518512961ae29c0077bfc57e8896e59a21f20af43e7ff5b7
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

SFTPB SLC44A4 TMEM130 IGF1R ELAPOR1 NOTCH3

1.77e-051871296ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellClub-club-14|World / Class top

SFTPB IDH2 SLC44A4 LRRC26 ELAPOR1 CTSH

1.77e-0518712964584de577d3736c89187e522497498e58d381c46
ToppCell10x5'-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

CR1 CR2 WDFY4 CD19 CTSH BTNL9

1.83e-051881296ab1384e6f71053946368502282aeebf1ba92d33e
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

SFTPB SLC44A4 TMEM130 IGF1R ELAPOR1 NOTCH3

1.94e-051901296756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell10x5'-GI_large-bowel-Lymphocytic_B-Memory_B_cells|GI_large-bowel / Manually curated celltypes from each tissue

ESPNL CR1 CR2 WDFY4 CD19 CTSH

2.06e-05192129631f7245bce79969674a775ecf175e7c6af68b503
ToppCelldistal-Hematologic-Basophil/Mast_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ATG9B ITGA2B LMO4 CR2 CSF1 SLC45A3

2.12e-051931296f22d0a2ea6bbdd625909ccb6a89aca89ab670306
ToppCelldistal-Hematologic-Basophil/Mast_2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ATG9B ITGA2B LMO4 CR2 CSF1 SLC45A3

2.12e-051931296dcdc1498726c68bf590bf84cb81e5f7fb7ba4d78
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN ADGRB2 CR1 TGFBR3 TMEM130 CRB2

2.18e-05194129643eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

STING1 ITGA2B LMO4 CR1 SLC45A3 PTGDR2

2.24e-051951296fbedb9978ded857fd35c2a8664f7579f42edaa36
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC44A4 SLC45A3 HHIPL2 ELAPOR1 CTSH NOTCH3

2.24e-051951296c87edbb8c92a0541b6de2632ac2f9cef44c7e304
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

VIPR1 RELN TFPI TGFBR3 TMEM44 BTNL9

2.24e-051951296094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

RELN TGFBR3 NTN4 IGF1R TMEM44 BTNL9

2.31e-051961296e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-Memory_B_cells|lymph-node_spleen / Manually curated celltypes from each tissue

CR1 CR2 WDFY4 CD19 CTSH BTNL9

2.31e-051961296c450cd6b799932f5cce8326d1079114abeb71e95
ToppCellLAM-Epithelial-AT2|LAM / Condition, Lineage and Cell class

SFTPB IL20RA TFPI B3GNT8 NTN4 CTSH

2.31e-0519612969165041ef3d56b4d069497fee03dd1c6e273211d
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B|lymph-node_spleen / Manually curated celltypes from each tissue

CR1 CR2 WDFY4 CD19 CTSH BTNL9

2.38e-0519712969837bd2cc28b79147fb5d1997631ef953fd020e4
ToppCellLAM-Epithelial|LAM / Condition, Lineage and Cell class

SFTPB IL20RA TFPI B3GNT8 NTN4 CTSH

2.38e-051971296e5cf07061f6d9db7f12ac17209b267373fa2270b
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ESPNL CR1 CR2 WDFY4 CD19 ZC3H12D

2.38e-051971296da61afba697ec49ca86e062d35a825280da558ac
ToppCellBiopsy_Control_(H.)-Epithelial-SCGB3A2+_SCGB1A1+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

SFTPB TMEM130 LRRC26 ELAPOR1 B4GALNT2 NOTCH3

2.44e-051981296a3d4b6e4259ded2193d94d2ff6d48cf67214fc35
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

STING1 LMO4 CR1 SLC45A3 C5AR1 PTGDR2

2.51e-051991296a24a319d3ba8f4759f742af27610b4d62e359a2d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VWA5B2 RELN CSMD3 NTN4 TMEM130 C1QTNF4

2.59e-0520012962f481e2fd248c02a5aa2e0248c16808df142fed2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VWA5B2 RELN CSMD3 NTN4 TMEM130 C1QTNF4

2.59e-052001296bd4b9f6b37f4a3c960c4149cf0cfd2caf3327d2d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VWA5B2 RELN CSMD3 NTN4 TMEM130 C1QTNF4

2.59e-052001296dc674124475edf83908b51a4e1454bc2dc4f06fa
ToppCellControl-Myeloid-Dendritic_cells-pDC|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CR1 CR2 WDFY4 TMEM210 LRRC26

6.48e-051451295bab85a72142b6257f7d424e5301f65b6dcdf745d
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr-Oligodendrocyte.Tfr.Slco3a1_(Slco3a1)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SFTPB TMEM210 SLC45A3 LRRC26

6.70e-05751294574ed1836f6bf5fa38a53af0a05fa4437f68f36b
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr-Oligodendrocyte.Tfr.Slco3a1_(Slco3a1)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SFTPB TMEM210 SLC45A3 LRRC26

6.70e-0575129445f7861bfeb1c6371b73cf2ea527801342e534bc
ToppCell356C-Myeloid-Mast_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

LMO4 CSF1 SLC45A3 TMEM44 PTGDR2

7.14e-0514812951668d8a9e680da335362744f36b05446c499347e
ToppCell356C-Myeloid-Mast_cell-|356C / Donor, Lineage, Cell class and subclass (all cells)

LMO4 CSF1 SLC45A3 TMEM44 PTGDR2

7.14e-05148129518511ba10765eda937c5a710626361f7e6b9b321
ToppCell(02)_Cycling_Basal_(regeneration)-(2)_48hpi|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint

ADAMTS13 SLC44A4 CTSA DDOST ELAPOR1

7.14e-051481295a061a745c09254e063411b7d835d5597a0007e29
ToppCellP03-Hematopoietic-Immune-immune_cell_unspecified|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ITGA2B WDFY4 ZC3H12D C5AR1 GP1BB

7.37e-05149129543d756f81d532b5c7f2306e6af9d072d496cbc8e
ToppCellP03-Hematopoietic-Immune|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ITGA2B WDFY4 ZC3H12D C5AR1 GP1BB

7.37e-0514912951c5a2572741c47246d455c865e8e1677c9f49598
ToppCellClub_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ADAMTS13 PTPRH HHIPL2 LRRC26 ELAPOR1

7.37e-05149129581c813588bb5efb7b31141a75d387210dcb76094
ToppCellCOVID-19_Severe-CD8+_T_naive|World / disease group, cell group and cell class

VIPR1 AMN LAMC3 PASK DMRTA1

8.61e-051541295b568417d88a78d8c46688847f0f5f4989bd36387
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA2B ADAD2 CSF1 HSD17B1 BTNL9

9.43e-051571295ed9c9feefc06c9536c03bedbc3397a2ee492a78e
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA2B ADAD2 CSF1 HSD17B1 BTNL9

9.43e-051571295fddcb24776b9f86e000208bae54541b15b2adefd
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC44A4 CD19 LRRC26 ZC3H12D CTSH

1.00e-041591295f0611a7bf15e2f7dfe828dd247650a30b3d6d44d
ToppCellmild_COVID-19_(asymptomatic)-B_intermediate|World / disease group, cell group and cell class (v2)

FFAR1 ESPNL WDFY4 CD19 BTNL9

1.03e-0416012956722934e153b72039c3c4308557d0ef879a30638
ToppCellClub_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

TMEM130 LRRC26 ELAPOR1 B4GALNT2 NOTCH3

1.06e-041611295bd08a23b415617f6e8748ed2668d578a860ecf91
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC3B ADGRB2 ZFPM1 B4GALNT2 CRB2

1.06e-041611295334f540dff3508d451e5e85e8e4e8f3b8d6b74e7
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC3B ADGRB2 ZFPM1 B4GALNT2 CRB2

1.06e-04161129581d44438e4be4e68a59247e62f02026301a8a0c5
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ATG9B RELN TMEM130 TMEM44 ECE2

1.06e-041611295dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMN B3GNT8 CD19 ZC3H12D CTSH

1.12e-0416312952a561aa4518cf52d8470eff083b84f942a2b2b5d
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC44A4 CD19 LRRC26 ZC3H12D CTSH

1.12e-041631295e04de78a52cc886623689a913f7852200a77605b
ToppCell10x5'-Lung-Lymphocytic_T_CD8-Tnaive/CM_CD8|Lung / Manually curated celltypes from each tissue

VIPR1 ATG9B AMN ATF6B PASK

1.12e-041631295c8e4440d1a857e4da83002303940dd42b273c92e
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC44A4 CD19 LRRC26 ZC3H12D CTSH

1.12e-0416312958509b87748ec460992ae6cedbb155e1c6f6e2e48
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF135 CR2 B3GNT8 CD19 ZC3H12D

1.16e-041641295b175258fb0885afd84d4a414c0ae441f880e8469
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF135 CR2 B3GNT8 CD19 ZC3H12D

1.16e-0416412958bcfc93220d7c99dddb32b7fa7fb9aec2a1c63fa
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA6B LRFN1 HMCN2 TMEM44 BTNL9

1.23e-0416612958e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCellmoderate-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADGRB2 GRIN2C LMO4 SLC45A3 PTGDR2

1.23e-041661295c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCellControl-Lymphocytic_B-B_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CR1 CR2 WDFY4 CD19 LRRC26

1.26e-041671295a15a70d3837b31cc83a2a9e3f1bbfd77a95f2312
ToppCellControl-Lymphocytic_B|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CR1 CR2 WDFY4 CD19 LRRC26

1.26e-041671295956da82394fd6a9f45fc2031796f12cc889542cd
ToppCellControl-Lymphocytic_B-B_cells-B-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CR1 CR2 WDFY4 CD19 LRRC26

1.26e-04167129569ed8a4a507190a1a66c4baf1f3e9be21ada39d8
ToppCelldroplet-Lung-nan-18m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA2B IGF1R CSF1 HSD17B1 BTNL9

1.33e-041691295f2e20049a17eee533d49bd5f24a51962d123d132
ToppCelldroplet-Pancreas-Exocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC3 STING1 LMO4 SLC44A4 SLC45A3

1.33e-04169129553690d6f9712b54aa99a0408aae930d64ae478e5
ToppCelldroplet-Lung-nan-18m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA2B IGF1R CSF1 HSD17B1 BTNL9

1.33e-0416912954c6892551e9dec94fc62b3beab1e6d424639a1e9
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell-B_activate-7|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ESPNL CR2 HPDL CD19 BTNL9

1.37e-041701295ee2ee67d90ae4596de8ccd620e37c82cf51651d4
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ESPNL CR2 HPDL CD19 BTNL9

1.37e-041701295d7ca0c6ce5d2b7de99346f87e07aa7fe728fa08a
ToppCellBAL-Mild-Lymphocyte-B-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ESPNL CR2 HPDL CD19 BTNL9

1.37e-04170129552787f6d529c285d9f0c04cc022710ead5b89b3f
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

NWD1 PAMR1 IL20RA WDFY4 CRB2

1.41e-04171129574be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCellCOVID-19-kidney-Bcells|COVID-19 / Disease (COVID-19 only), tissue and cell type

CR1 CR2 WDFY4 CD19 ZC3H12D

1.41e-0417112958e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCellClub-club-3|World / Class top

VIPR1 SLC44A4 SLC45A3 LRRC26 ELAPOR1

1.45e-04172129534fbb82a2ec77dd183cf26b38edeb7e936b707bc
ToppCellImmune-mast_cell|World / Lineage, Cell type, age group and donor

ITGA2B LMO4 SLC45A3 TMEM44 PTGDR2

1.45e-0417212956e8e0aac5a20dbc789bf8c6916833bb8709a411a
ToppCellASK440-Epithelial-Transformed_epithelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

BRME1 CELSR2 ELAPOR1 RHBDD3 SLC35E4

1.45e-041721295df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VIPR1 TMEM235 NTN4 TMEM44 BTNL9

1.49e-041731295f193c63cc536d891c9d23043765e320252bb6e65
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

VWA5B2 ATG9B AMN CDKL1 TMEM130

1.49e-0417312957e3897868dd3f6e4974f593c60649a543ffc8693
ToppCelldroplet-Lung-3m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGA2B IGF1R CSF1 C5AR1 BTNL9

1.49e-041731295120dd20e8a71f9169a1596b6171df7aa0b96dd15
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|367C / Donor, Lineage, Cell class and subclass (all cells)

SFTPB SLC44A4 LRRC26 ELAPOR1 DMRTA1

1.49e-041731295c2d973356c40e0284fd3bd7733a164b141c66008
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D9B IDH2 IGF1R BTNL9 NOTCH3

1.49e-0417312955d7c53c6d1cdd385e44b79b82faec901747d1736
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA2B IGF1R CSF1 C5AR1 BTNL9

1.49e-0417312953612772632ddf11eb48579cae9a8ccab6b3f1f52
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|367C / Donor, Lineage, Cell class and subclass (all cells)

SFTPB SLC44A4 LRRC26 ELAPOR1 DMRTA1

1.49e-041731295d8e965ff7e9b758876ec1521c1ccedd739e8d673
ToppCellIIH-CD8-naive_CD4|IIH / Condition, Cell_class and T cell subcluster

AUH PPCS PASK OSBPL7 SLC35E4

1.49e-0417312954f2843371d18af766c1892529ce286f56c956fde
ToppCelldroplet-Lung-3m-Hematologic-myeloid-Basophil/Mast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGA2B IGF1R CSF1 C5AR1 BTNL9

1.49e-041731295b2c55084ef6dac0e329c2e65c24cfe0045859c30
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA2B IGF1R CSF1 C5AR1 BTNL9

1.49e-0417312954dc261ebcdb9bdcfca1451da1bd254f0dc5de203
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIPR1 AMN SLC44A4 NTN4 DMRTA1

1.49e-04173129581c36b9fe02c59099f080b2db02f4eaf2783911f
ToppCell10x5'-blood-Mast-Mast_cells|blood / Manually curated celltypes from each tissue

LMO4 CDKL1 CSF1 SLC45A3 PTGDR2

1.53e-041741295a5838821bba2be790d32331ff529d466e9974268
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPBAR1 B4GALNT2 WDR17 NOTCH3 GP1BB

1.53e-041741295778e0317c0c63fa4efd74114feb760975b819d92
DiseaseFamilial Thrombotic Thrombocytopenic Purpura

ADAMTS13 TFPI

1.03e-0441232C1956258
DiseaseCongenital Thrombotic Thrombocytopenic Purpura

ADAMTS13 TFPI

1.03e-0441232C1268935
DiseasePurpura, Thrombotic Thrombocytopenic

ADAMTS13 TFPI

1.03e-0441232C0034155
Diseasethrombotic thrombocytopenic purpura (is_marker_for)

ADAMTS13 TFPI

1.03e-0441232DOID:10772 (is_marker_for)
Diseasebasophil measurement

RPN1 ZFPM1 LMO4 THADA

1.17e-04601234EFO_0803539
Diseasevesicoureteral reflux (is_marker_for)

IGF1R CSF1

1.71e-0451232DOID:9620 (is_marker_for)
DiseaseIMMUNODEFICIENCY, COMMON VARIABLE, 2

CR2 CD19

1.71e-0451232240500
DiseaseImmunodeficiency, common variable, 2

CR2 CD19

1.71e-0451232cv:C3150354
Diseasepappalysin-1 measurement

SEMA6B RPN1

2.56e-0461232EFO_0802845
DiseaseNeonatal Alloimmune Thrombocytopenia

ITGA2B GP1BB

2.56e-0461232C3853779
DiseaseFNAITP

ITGA2B GP1BB

2.56e-0461232C3854603
DiseaseAutosomal dominant macrothrombocytopenia

ITGA2B GP1BB

3.57e-0471232C4304021
DiseaseGrowth Disorders

RNF135 IDH2 IGF1R

4.56e-04361233C0018273
Disease3-Methylglutaconic aciduria

AUH CLPB

4.75e-0481232cv:C3696376
Diseasedisseminated intravascular coagulation (is_marker_for)

ADAMTS13 TFPI

7.59e-04101232DOID:11247 (is_marker_for)
Diseasehigh grade glioma (implicated_via_orthology)

IDH2 IGF1R CSF1

8.26e-04441233DOID:3070 (implicated_via_orthology)
DiseaseImmunoglobulin Deficiency, Late-Onset

CR2 CD19

9.25e-04111232C2936665
DiseaseAcquired Hypogammaglobulinemia

CR2 CD19

9.25e-04111232C2936664
Diseasecomplement C1q tumor necrosis factor-related protein 1 measurement

CELSR2 CTSH

1.11e-03121232EFO_0801493
Diseasegranulins measurement

ITGA2B CELSR2

1.11e-03121232EFO_0008141
DiseaseCommon variable immunodeficiency

CR2 CD19

1.30e-03131232cv:C0009447
Diseasetoxic shock syndrome (is_implicated_in)

SFTPB TFPI

1.30e-03131232DOID:14115 (is_implicated_in)
DiseaseCD209 antigen measurement

ADAMTS13 CELSR2

1.52e-03141232EFO_0008077
DiseaseImpaired cognition

CR1 NOTCH3

1.52e-03141232C0338656
Diseaseserum gamma-glutamyl transferase measurement

AMN SFTPB RNF135 ZFPM1 CSMD3 THADA IGF1R VKORC1 CELSR2 PTTG1IP AFG1L

1.57e-0391412311EFO_0004532
DiseaseCommon Variable Immunodeficiency

CR2 CD19

1.75e-03151232C0009447
Diseasepulmonary fibrosis (is_implicated_in)

SFTPB TFPI

1.99e-03161232DOID:3770 (is_implicated_in)
DiseaseCerebrovascular accident

ITGA2B VKORC1 NOTCH3

2.23e-03621233C0038454
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Positive

ITGA2B TFPI IGF1R GP1BB

2.24e-031311234C4704862
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Negative

ITGA2B TFPI IGF1R GP1BB

2.24e-031311234C4552091
DiseaseJuvenile arthritis

ITGA2B TFPI IGF1R GP1BB

2.24e-031311234C3495559
DiseaseJuvenile psoriatic arthritis

ITGA2B TFPI IGF1R GP1BB

2.24e-031311234C3714758
DiseaseHypogammaglobulinemia

CR2 CD19

2.25e-03171232C0086438
DiseaseJuvenile-Onset Still Disease

ITGA2B TFPI IGF1R GP1BB

2.50e-031351234C0087031
Diseasepolycystic kidney disease (biomarker_via_orthology)

GPBAR1 CTSH

2.81e-03191232DOID:0080322 (biomarker_via_orthology)
Diseaseprogranulin measurement

ITGA2B CELSR2

3.77e-03221232EFO_0004625

Protein segments in the cluster

PeptideGeneStartEntry
LGLSGEWVPTPCALS

LINC00311

71

Q8N616
LCSVPGARGWRLPSV

URB2

1101

Q14146
PLSGEKASLLWRACP

URB2

1281

Q14146
RAGSERCPWASLLLP

ADGRB2

1116

O60241
WFLGACLAAVPRAGP

BTNL9

396

Q6UXG8
TCRGLSLNWSLGDPG

ADAD2

481

Q8NCV1
ALRSLWSSLCLGPAP

ADPGK

31

Q9BRR6
GLGPASIECLPNGTW

CSMD3

2731

Q7Z407
WRACPGPLSSLTLSV

ACBD4

251

Q8NC06
LCLELRGADPAWGPF

B4GALNT2

41

Q8NHY0
APGLPGCQTKELSLW

BCORL1

791

Q5H9F3
CGAWAAALAPLATAP

AFG1L

26

Q8WV93
LGLLGPAACWALGPT

C1QTNF4

6

Q9BXJ3
RLLLGWAPGQPFSSC

DPH2

236

Q9BQC3
WICAALLQPLGGRCP

AMN

221

Q9BXJ7
PWSCRLLGIGGHLSP

CELSR2

111

Q9HCU4
WKSVLAGPLRTPLCG

APEX2

456

Q9UBZ4
HWPFGGAACSILPSL

C5AR1

101

P21730
SCDLGLLSSPCWRLP

ANXA2R

51

Q3ZCQ2
SDGAAPRAGLAWSPC

ADAMTS13

251

Q76LX8
DLLWASLPECGNPGR

NWD1

521

Q149M9
GLRWFTPASEVPLCG

PBLD

66

P30039
LTGARWPRPLCAAAG

POLDIP2

21

Q9Y2S7
WPRPLCAAAGAGAFS

POLDIP2

26

Q9Y2S7
GCWPALPKPRSGLAS

ESPNL

686

Q6ZVH7
LRGLSSGWSSPLLPA

PASK

111

Q96RG2
SLSGCGSWQPRKLPV

FLCN

331

Q8NFG4
GSEAPWCFTLRPGTR

MST1L

321

Q2TV78
PPVTAGSLSWKRCAG

LMO4

11

P61968
CSAWLCPGLRLPGSL

AUH

26

Q13825
FASWPGTPAPILGCR

CRB2

1041

Q5IJ48
TWAGPLLFASLPALG

GPBAR1

131

Q8TDU6
ALSSVGRAWCPPGFI

HMCN2

4841

Q8NDA2
LLLLWAGASRGQPCP

LRFN1

21

Q9P244
VWREPKLCSGGISLP

ELAPOR1

881

Q6UXG2
ELRAACAPGPLCWGA

GP1BB

136

P13224
GTPRSSGLFWRVTCP

ECE2

61

P0DPD6
LCLGEPAPFWRGVLS

HR

41

O43593
AALSLWPTSGEICGP

IGF1R

21

P08069
RALCGWTPSSGATPR

DLAT

56

P10515
VRRGSCPLLPGPSAW

FAM218A

6

Q96MZ4
ALWCRVTKPVPAGGL

ZFPM1

171

Q8IX07
PGWSGRLCDIRSLPC

NOTCH3

1026

Q9UM47
WLLLPLLGAVCASGP

DDOST

31

P39656
PARLLGWLLGSCAAS

PTGDR2

366

Q9Y5Y4
LLAAPWGRAVPCVSG

IL20RA

21

Q9UHF4
LSFIWIAPPAGTGCV

RELN

141

P78509
LACTPGSSPTLLRWF

HPDL

166

Q96IR7
LTSPGGTASPLCWRS

NTN3

81

O00634
SPVVLWLNGGPGCSS

CTSA

76

P10619
GLWSGPLPRVTLHCS

POP1

946

Q99575
WLSALRPSGPALSGL

PPCS

101

Q9HAB8
LCRASGSRPAWAPAA

IDH2

11

P48735
GLGPASWCLEPGSVA

BRME1

291

Q0VDD7
QERGTWSGPAPLCKL

CR2

581

P20023
AAGRCPPTTWLGSLL

CSF1

6

P09603
ALASGAWPLPASLCP

FFAR1

66

O14842
GNGVWSSPAPRCGIL

CR1

476

P17927
GNGVWSSPAPRCGIL

CR1

926

P17927
CVFAELLSGVPLWPG

CDKL1

191

Q00532
LWLSCGVPPDSVSRG

CD19

196

P15391
AVVLSWAPPVGLSCG

FNDC3B

291

Q53EP0
LWEAARALACPPGSL

HSD17B1

46

P14061
LQRLLCSGLSWPPGG

DMRTA1

156

Q5VZB9
LLPARCPLPWGGSAA

ATG9B

376

Q674R7
CPLPWGGSAAFLSRG

ATG9B

381

Q674R7
PLLCAGAWLLGVPVC

CTSH

6

P09668
ALSCWLPLRASFPQG

LYPLA1

141

O75608
CWAPRGRLLASSPAG

MAPKAPK5-AS1

91

Q8N8E1
LLPSAPALGRCFPWT

SLC44A4

171

Q53GD3
KCLAAATWGRLPGPE

CLPB

81

Q9H078
RFGPCATLWASLDPV

FHOD1

646

Q9Y613
TPNLCGGLHCRAPWL

HHIPL2

6

Q6UWX4
GGLHCRAPWLSSGIL

HHIPL2

11

Q6UWX4
SAACRSFPQWLPGGG

B3GNT8

121

Q7Z7M8
SSCRIPLWGFPSLGQ

C1orf159

206

Q96HA4
PLPGLGWACDVALLR

IRGQ

496

Q8WZA9
RTGKWSGRAPSCIPI

PAMR1

431

Q6UXH9
CLPAASGPGADVSLW

OSBPL7

466

Q9BZF2
LGCQDSPGLRAAWPT

NUTM2B

701

A6NNL0
CAPPVSRAGGRLLSW

PLD6

226

Q8N2A8
TRPSGFLGDPCLWDQ

TARS2

496

Q9BW92
GLLDWPATLPCGHSF

RNF135

26

Q8IUD6
LSACLVTLWGLGEPP

STING1

26

Q86WV6
LFCLLSKSGWRPPSP

THADA

1851

Q6YHU6
LCLDPATGRPWTGAP

SSPOP

4581

A2VEC9
LLLLPTLCGPGTAAW

SFTPB

11

P07988
SLPCGWLCTAIGLPT

TMCO3

281

Q6UWJ1
WDEKGLLLAPGCLPS

TMCO4

526

Q5TGY1
LPDGGSCLCTAWPRR

SPATA5L1

51

Q9BVQ7
PGAAWIGPLRLGLCS

TMEM150B

146

A6NC51
WTDRGCTCPILNPGL

NTN4

571

Q9HB63
LLLLGTWAPAPGSAS

RPN1

11

P04843
PWGISATAALRPAAC

PRDX3

21

P30048
KLRWFSECLSPPGGS

WDR17

741

Q8IZU2
ATARSLWGTPRLPCS

IARS2

16

Q9NSE4
LCPWRAEGGQCPSLL

ITGA2B

86

P08514
AGWLAGLLCPDPRPL

SLC45A3

106

Q96JT2
ARPLWGPCLGLRAAA

MRPL12

6

P52815
LTPWACGSHTPLLAG

TBC1D9B

871

Q66K14
SGCLLWDVPAPSLGA

ATF6B

206

Q99941
PSCAGAAWSARGAPL

C10orf95

166

Q9H7T3
ALSGRAPSILCSVPW

SHANK2-AS3

26

Q9BTD1
AGCWPLRLLATPGSL

RHBDD3

206

Q9Y3P4
WPVSCLRGGPLGLTY

TMEM210

6

A6NLX4
WAPDGSCIFLSPGTR

SEMA6B

546

Q9H3T3
PLPARWLCVLAGALA

VIPR1

6

P32241
PLLGCFTTPGVQLWA

ZYG11B

656

Q9C0D3
CLVTAWPRAPSGAGS

nan

21

Q96NJ1
LSAAWTLSLSPPICG

TMEM235

196

A6NFC5
GSPGWVRLALCLTGL

VKORC1

6

Q9BQB6
LWLPKSLSPGCGREL

UBE4B

571

O95155
PPGGLTFSCWFLISR

WDFY4

1066

Q6ZS81
GPLACREPSGRWVLT

TMPRSS9

1011

Q7Z410
VFALALPLSLGPCWA

TMEM44

136

Q2T9K0
PPASLCKLSSARWGV

PTTG1IP

76

P53801
LPSDLPSWSCVGAVG

SLC35G6

246

P0C7Q6
FHGPSWCLTPADRGL

TFPI

211

P10646
GVPEPGSPRSWLLLC

PRSS55

326

Q6UWB4
ACSLTPRLGGPDWVS

ZC3H12D

366

A2A288
LQEPPWSLGCTGLKA

ZNF333

131

Q96JL9
SLAWGEPAGSRSCPL

VWA5B2

711

Q8N398
ACLLPWAPAGVAAGL

TMEM130

16

Q8N3G9
PPTAGDSRLWACILL

SLC35E4

246

Q6ICL7
LRFRCSWPGGAPAAS

VSIG10L

511

Q86VR7
CWLLGLRAAFEPRPG

TIGD5

476

Q53EQ6
CGSGPAPLLVLWSFT

VSIG10L2

56

P0DP72
ECSLRGGTPPAQLLW

VSIG10L2

521

P0DP72
LLGLCSWTGARAPAP

PTPRH

16

Q9HD43
LGGSCSLRRWPPLPT

TTLL10

576

Q6ZVT0
PWSCSGVILSRSPGL

TYSND1

31

Q2T9J0
PLNGCGTRPRWSALD

TGFBR3

501

Q03167
SLGPRTLSSCSPWDG

ZAR1L

106

A6NP61
WPGLSALAVRFLGCP

ZBED4

1111

O75132
SDCGSPWGPLDILLG

LAMC3

1041

Q9Y6N6
CVWPGRLTLSPLTAF

LRRC26

231

Q2I0M4
GFPGPCTWRRISSLE

GRIN2C

1216

Q14957