Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellularly ATP-gated monoatomic cation channel activity

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

2.25e-1071305GO:0004931
GeneOntologyMolecularFunctionATP-gated ion channel activity

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

1.34e-0991305GO:0035381
GeneOntologyMolecularFunctionprotein kinase activity

CDC42BPG DDR1 CDC42BPA CAMK1D MYLK GRK7 NTRK2 NTRK3 HIPK2 WNK1 CDC42BPB GRK1 TXK MST1R BTK PRKCH EIF2AK2 EIF2AK3

6.93e-0860013018GO:0004672
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

CDC42BPG DDR1 CDC42BPA CAMK1D MYLK GRK7 NTRK2 NTRK3 HIPK2 PFKM WNK1 CDC42BPB GRK1 TXK MST1R BTK PRKCH EIF2AK2 EIF2AK3

1.69e-0770913019GO:0016773
GeneOntologyMolecularFunctionnucleotide receptor activity

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

2.61e-07221305GO:0016502
GeneOntologyMolecularFunctionpurinergic nucleotide receptor activity

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

2.61e-07221305GO:0001614
GeneOntologyMolecularFunctionkinase activity

CDC42BPG DDR1 CDC42BPA CAMK1D MYLK GRK7 NTRK2 NTRK3 HIPK2 PFKM WNK1 CDC42BPB GRK1 TXK MST1R BTK PRKCH EIF2AK2 EIF2AK3

5.27e-0776413019GO:0016301
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

DDR1 NTRK2 NTRK3 HIPK2 TXK MST1R BTK EIF2AK2

4.90e-061451308GO:0004713
GeneOntologyMolecularFunctionexcitatory extracellular ligand-gated monoatomic ion channel activity

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

8.55e-06431305GO:0005231
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

CDC42BPG DDR1 CDC42BPA CAMK1D MYLK GRK7 NTRK2 NTRK3 HIPK2 PFKM WNK1 CDC42BPB GRK1 TXK MST1R BTK PRKCH EIF2AK2 EIF2AK3

1.05e-0593813019GO:0016772
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

CDC42BPG CDC42BPA CAMK1D MYLK GRK7 HIPK2 WNK1 CDC42BPB GRK1 PRKCH EIF2AK2 EIF2AK3

3.55e-0544613012GO:0004674
GeneOntologyMolecularFunctionrhodopsin kinase activity

GRK7 GRK1

1.26e-0431302GO:0050254
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

1.47e-04771305GO:0005230
GeneOntologyMolecularFunctionneurotrophin receptor activity

NTRK2 NTRK3

4.15e-0451302GO:0005030
GeneOntologyMolecularFunctioneukaryotic translation initiation factor 2alpha kinase activity

EIF2AK2 EIF2AK3

6.20e-0461302GO:0004694
GeneOntologyMolecularFunctionprotein serine kinase activity

CDC42BPG CDC42BPA CAMK1D HIPK2 WNK1 CDC42BPB PRKCH EIF2AK2 EIF2AK3

6.28e-043631309GO:0106310
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

DDR1 NTRK2 NTRK3 MST1R

8.54e-04651304GO:0004714
GeneOntologyMolecularFunctiontranslation termination factor activity

GSPT1 GSPT2

8.65e-0471302GO:0008079
GeneOntologyMolecularFunctionG protein-coupled receptor kinase activity

GRK7 GRK1

8.65e-0471302GO:0004703
GeneOntologyMolecularFunctiontranslation release factor activity

GSPT1 GSPT2

8.65e-0471302GO:0003747
GeneOntologyMolecularFunctionmagnesium ion binding

ADCY10 CDC42BPG CDC42BPA MTHFD2 WNK1 CDC42BPB P2RX7

1.18e-032471307GO:0000287
GeneOntologyMolecularFunctiontranslation initiation factor binding

CACNA1C EIF2AK3 TBL2

2.08e-03391303GO:0031369
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

2.24e-031401305GO:0099094
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

DDR1 NTRK2 NTRK3 MST1R

2.31e-03851304GO:0019199
GeneOntologyBiologicalProcessregulation of anatomical structure size

ADCY10 SEMA6C DOCK4 CACNA1C NTRK3 PFN2 WNK1 SHANK3 SLC12A5 SPTBN5 P2RX1 P2RX4 CLCN6 P2RX7 TENM1 MMP2 CTTN HCLS1 RBFOX2

7.90e-0961812719GO:0090066
GeneOntologyBiologicalProcesspositive regulation of transport

CACNA1C FLNA RAP1GAP CAMK1D MYLK CD2AP COLEC10 PFKM WNK1 SHANK3 TNFSF11 MALRD1 P2RX1 P2RX3 P2RX4 P2RX7 SYNJ1 CADPS BTK TENM1 SCP2 ABCB11 HSPA2 HCLS1

3.95e-08108112724GO:0051050
GeneOntologyBiologicalProcesspurinergic nucleotide receptor signaling pathway

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

1.69e-06331275GO:0035590
GeneOntologyBiologicalProcessregulation of cellular component size

ADCY10 SEMA6C NTRK3 PFN2 WNK1 SHANK3 SLC12A5 SPTBN5 CLCN6 P2RX7 TENM1 CTTN HCLS1

2.34e-0642612713GO:0032535
GeneOntologyBiologicalProcesspositive regulation of monoatomic ion transmembrane transport

CACNA1C FLNA WNK1 SHANK3 P2RX1 P2RX3 P2RX4 P2RX7 HSPA2

3.00e-061921279GO:0034767
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

FLNA RAP1GAP WNT1 NTRK2 NTRK3 PFN2 CLIP1 SHANK3 DRG1 SPTBN5 P2RX4 P2RX7 SACS METTL18 BTK TENM1 PRKCH CTTN TACSTD2 HSPA2 EIF2AK2 HCLS1

3.33e-06118912722GO:0044087
GeneOntologyBiologicalProcessresponse to ATP

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

4.53e-06401275GO:0033198
GeneOntologyBiologicalProcesscell volume homeostasis

WNK1 SHANK3 SLC12A5 CLCN6 P2RX7

5.79e-06421275GO:0006884
GeneOntologyBiologicalProcesspositive regulation of monoatomic ion transport

CACNA1C FLNA MYLK WNK1 SHANK3 P2RX1 P2RX3 P2RX4 P2RX7 HSPA2

5.98e-0626612710GO:0043270
GeneOntologyBiologicalProcesstransmission of nerve impulse

NTRK2 NTRK3 PRX P2RX1 P2RX3 P2RX4 P2RX7

6.02e-061121277GO:0019226
GeneOntologyBiologicalProcessmuscle contraction

ADCY10 DOCK4 CACNA1C FLNA MYL1 MYLK P2RX1 P2RX3 P2RX4 P2RX6 MYL6B CTTN

6.94e-0640012712GO:0006936
GeneOntologyBiologicalProcessmuscle system process

ADCY10 DOCK4 CACNA1C FLNA MYL1 MYLK GTF2IRD2B P2RX1 P2RX3 P2RX4 P2RX6 MYL6B GTF2IRD2 CTTN

7.17e-0654712714GO:0003012
GeneOntologyBiologicalProcesspeptidyl-amino acid modification

ADCY10 CDC42BPG DDR1 CDC42BPA CAMK1D NTRK2 NTRK3 HIPK2 PFN2 WNK1 CDC42BPB METAP1 METTL18 BTK TENM1 PRKCH PPIL2 EIF2AK3 HCLS1

8.29e-0697612719GO:0018193
GeneOntologyBiologicalProcessregulation of cell size

ADCY10 SEMA6C NTRK3 WNK1 SHANK3 SLC12A5 CLCN6 P2RX7 CTTN

1.08e-052251279GO:0008361
GeneOntologyBiologicalProcesspositive regulation of cation transmembrane transport

CACNA1C FLNA WNK1 P2RX1 P2RX3 P2RX4 P2RX7 HSPA2

1.25e-051741278GO:1904064
GeneOntologyBiologicalProcessregulation of cell projection organization

ADCY10 SEMA6C FLNA DDR1 RAP1GAP CAMK1D WNT1 NTRK2 NTRK3 PFN2 CLIP1 SHANK3 P2RX4 P2RX7 TENM1 CTTN TACSTD2

2.24e-0586312717GO:0031344
GeneOntologyBiologicalProcessaction potential

CACNA1C FLNA NTRK2 NTRK3 P2RX1 P2RX3 P2RX4 P2RX7

3.52e-052011278GO:0001508
GeneOntologyBiologicalProcessactin filament-based process

ADCY10 CACNA1C CDC42BPG FLNA MYL1 CDC42BPA CD2AP MYOM3 PFN2 CDC42BPB SHANK3 SPTBN5 MYL6B TENM1 CTTN TACSTD2 HCLS1

4.48e-0591212717GO:0030029
GeneOntologyBiologicalProcesspositive regulation of calcium ion transport

CACNA1C MYLK P2RX1 P2RX3 P2RX4 P2RX7 HSPA2

4.77e-051541277GO:0051928
GeneOntologyBiologicalProcesspositive regulation of transmembrane transport

CACNA1C FLNA WNK1 SHANK3 P2RX1 P2RX3 P2RX4 P2RX7 HSPA2

4.97e-052731279GO:0034764
GeneOntologyBiologicalProcesspositive regulation of molecular function

CACNA1C DDR1 RAP1GAP CAMK1D DOCK8 WNT1 NTRK2 NTRK3 HIPK2 PFN2 SHANK3 MST1R TNFSF11 P2RX1 P2RX7 BTK TENM1 PRKCH HSPA2 EIF2AK2 EIF2AK3 RIC1

5.83e-05143012722GO:0044093
GeneOntologyBiologicalProcesspositive regulation of calcium ion transmembrane transport

CACNA1C P2RX1 P2RX3 P2RX4 P2RX7 HSPA2

5.84e-051091276GO:1904427
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

ADCY10 SEMA6C FLNA DDR1 RAP1GAP CAMK1D WNT1 NTRK2 NTRK3 PFN2 CLIP1 SHANK3 P2RX4 P2RX7 TENM1 TACSTD2

6.44e-0584612716GO:0120035
GeneOntologyBiologicalProcesspeptidyl-threonine phosphorylation

ADCY10 CDC42BPG CDC42BPA HIPK2 WNK1 CDC42BPB

7.87e-051151276GO:0018107
GeneOntologyBiologicalProcessregulation of actin filament-based process

ADCY10 CACNA1C FLNA CD2AP PFN2 SHANK3 SPTBN5 TENM1 CTTN TACSTD2 HCLS1

8.54e-0543812711GO:0032970
GeneOntologyBiologicalProcesshindbrain radial glia guided cell migration

FLNA ARL13B RBFOX2

9.83e-05151273GO:0021932
GeneOntologyBiologicalProcesspositive regulation of membrane depolarization

ADCY10 CACNA1C P2RX7

1.20e-04161273GO:1904181
GeneOntologyBiologicalProcesspositive regulation of prostaglandin secretion

TNFSF11 P2RX4 P2RX7

1.20e-04161273GO:0032308
GeneOntologyBiologicalProcesspeptidyl-serine phosphorylation

CAMK1D NTRK2 NTRK3 HIPK2 PFN2 WNK1 TENM1 PRKCH EIF2AK3

1.22e-043071279GO:0018105
GeneOntologyBiologicalProcesspeptidyl-threonine modification

ADCY10 CDC42BPG CDC42BPA HIPK2 WNK1 CDC42BPB

1.25e-041251276GO:0018210
GeneOntologyBiologicalProcesscalcium ion transport into cytosol

CACNA1C P2RX3 P2RX4 P2RX7

1.28e-04421274GO:0060402
GeneOntologyBiologicalProcessexcitatory postsynaptic potential

SHANK3 P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

1.55e-041301276GO:0060079
GeneOntologyBiologicalProcesspeptidyl-serine modification

CAMK1D NTRK2 NTRK3 HIPK2 PFN2 WNK1 TENM1 PRKCH EIF2AK3

1.62e-043191279GO:0018209
GeneOntologyBiologicalProcessregulation of cell projection assembly

RAP1GAP WNT1 PFN2 P2RX4 P2RX7 TENM1 CTTN TACSTD2

1.66e-042511278GO:0060491
GeneOntologyBiologicalProcesssecretion

CACNA1C DDR1 PTGES2 NTRK2 CD2AP PFKM PFN2 WNK1 TNFSF11 MALRD1 P2RX1 P2RX4 P2RX7 SYNJ1 CADPS BTK ABCB11 EIF2AK3 RIC1

1.71e-04122112719GO:0046903
GeneOntologyBiologicalProcessregulation of prostaglandin secretion

TNFSF11 P2RX4 P2RX7

1.74e-04181273GO:0032306
GeneOntologyBiologicalProcessregulation of system process

ADCY10 DOCK4 CACNA1C FLNA WNK1 SHANK3 GTF2IRD2B P2RX1 P2RX4 GTF2IRD2 MMP2 CTTN EIF2AK3 RBFOX2

1.74e-0473412714GO:0044057
GeneOntologyBiologicalProcesssmooth muscle contraction

DOCK4 CACNA1C MYLK P2RX1 P2RX3 CTTN

1.75e-041331276GO:0006939
GeneOntologyBiologicalProcessregulation of membrane potential

ADCY10 CACNA1C FLNA NTRK2 NTRK3 SHANK3 P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 RBFOX2

1.77e-0455912712GO:0042391
GeneOntologyBiologicalProcesspositive regulation of establishment of protein localization

ADCY10 CACNA1C FLNA CD2AP PFKM MALRD1 P2RX7 CCT5 TENM1 HCLS1

1.99e-0440312710GO:1904951
GeneOntologyBiologicalProcessresponse to wounding

FLNA DDR1 VWF MORN4 MYLK NTRK3 CD2AP METAP1 P2RX1 P2RX4 ENTPD2 MMP2 KLKB1

2.17e-0465912713GO:0009611
GeneOntologyBiologicalProcessresponse to glial cell derived neurotrophic factor

RAP1GAP CD2AP

2.24e-0441272GO:1990790
GeneOntologyBiologicalProcesspositive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway

ADCY10 MMP2

2.24e-0441272GO:1903378
GeneOntologyBiologicalProcessregulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway

ADCY10 WNT1 MMP2

2.41e-04201273GO:1903376
GeneOntologyBiologicalProcessregulation of cytoskeleton organization

FLNA CD2AP PFN2 CLIP1 SHANK3 DRG1 SPTBN5 P2RX7 TENM1 CTTN TACSTD2 HCLS1

2.45e-0457912712GO:0051493
GeneOntologyBiologicalProcesscalcium-mediated signaling

CACNA1C TNFSF11 P2RX1 P2RX3 P2RX4 P2RX7 BTK EIF2AK3

2.46e-042661278GO:0019722
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

FLNA RAP1GAP MYLK WNT1 CD2AP PFN2 CFAP298 P2RX4 P2RX7 ARL13B TENM1 CTTN TACSTD2

2.55e-0467012713GO:0120031
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

ADCY10 FLNA DDR1 RAP1GAP CAMK1D WNT1 NTRK2 NTRK3 COLEC10 PFN2 WNK1 CLIP1 SHANK3 DRG1 P2RX7 SYNJ1 CCT5 BTK TENM1 CTTN

2.55e-04136612720GO:0051130
GeneOntologyBiologicalProcesspositive regulation of calcium ion transport into cytosol

P2RX3 P2RX4 P2RX7

2.80e-04211273GO:0010524
GeneOntologyBiologicalProcesscellular response to ATP

P2RX3 P2RX4 P2RX7

2.80e-04211273GO:0071318
GeneOntologyBiologicalProcesspositive regulation of cytoskeleton organization

FLNA PFN2 CLIP1 DRG1 P2RX7 TENM1 CTTN

2.82e-042051277GO:0051495
GeneOntologyBiologicalProcesspositive regulation of protein localization

ADCY10 CACNA1C FLNA CD2AP PFKM MALRD1 P2RX7 CCT5 TENM1 PRKCH EIF2AK3 HCLS1

2.95e-0459112712GO:1903829
GeneOntologyBiologicalProcessresponse to cold

ACADVL P2RX3 HSPA2 EIF2AK3

2.95e-04521274GO:0009409
GeneOntologyBiologicalProcesschemical synaptic transmission, postsynaptic

SHANK3 P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

3.01e-041471276GO:0099565
GeneOntologyBiologicalProcesscell projection assembly

FLNA RAP1GAP MYLK WNT1 CD2AP PFN2 CFAP298 P2RX4 P2RX7 ARL13B TENM1 CTTN TACSTD2

3.15e-0468512713GO:0030031
GeneOntologyBiologicalProcessneuron intrinsic apoptotic signaling pathway in response to oxidative stress

ADCY10 WNT1 MMP2

3.22e-04221273GO:0036480
GeneOntologyBiologicalProcessprostaglandin secretion

TNFSF11 P2RX4 P2RX7

3.22e-04221273GO:0032310
GeneOntologyBiologicalProcesspositive regulation of phosphorylation

ADCY10 DDR1 WNT1 NTRK2 NTRK3 HIPK2 PFN2 GRK1 MST1R TNFSF11 P2RX7 TENM1 HSPA2 HCLS1

3.24e-0478012714GO:0042327
GeneOntologyBiologicalProcessregulation of vasoconstriction

DOCK4 CACNA1C P2RX1 MMP2 RBFOX2

3.51e-04981275GO:0019229
GeneOntologyBiologicalProcesschemotaxis

SEMA6C DOCK4 CAMK1D DUSP1 NTRK3 COLEC10 WNK1 TNFSF11 P2RX4 MMP2 CTTN

3.58e-0451712711GO:0006935
GeneOntologyBiologicalProcesscell migration in hindbrain

FLNA ARL13B RBFOX2

3.69e-04231273GO:0021535
GeneOntologyBiologicalProcessATP transport

ADCY10 SLC25A24 P2RX7

3.69e-04231273GO:0015867
GeneOntologyBiologicalProcesstaxis

SEMA6C DOCK4 CAMK1D DUSP1 NTRK3 COLEC10 WNK1 TNFSF11 P2RX4 MMP2 CTTN

3.70e-0451912711GO:0042330
GeneOntologyBiologicalProcessformation of radial glial scaffolds

FLNA ARL13B

3.72e-0451272GO:0021943
GeneOntologyBiologicalProcesspositive regulation of intracellular signal transduction

ADCY10 FLNA DDR1 VWF NTRK2 NTRK3 HIPK2 IFI35 MST1R TNFSF11 P2RX3 P2RX4 P2RX7 BTK TENM1 MMP2 EIF2AK2 EIF2AK3 HCLS1

3.74e-04129912719GO:1902533
GeneOntologyBiologicalProcessregulation of supramolecular fiber organization

FLNA PFN2 CLIP1 SHANK3 DRG1 SPTBN5 TENM1 CTTN TACSTD2 HCLS1

3.86e-0443812710GO:1902903
GeneOntologyBiologicalProcesspositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

DDR1 NTRK2 NTRK3 MST1R TNFSF11 P2RX4 HCLS1

3.98e-042171277GO:0051897
GeneOntologyBiologicalProcesspositive regulation of icosanoid secretion

TNFSF11 P2RX4 P2RX7

4.20e-04241273GO:0032305
GeneOntologyBiologicalProcessregulation of secretion

CACNA1C NTRK2 CD2AP PFKM PFN2 WNK1 TNFSF11 MALRD1 P2RX1 P2RX4 P2RX7 CADPS ABCB11 RIC1

4.22e-0480112714GO:0051046
GeneOntologyBiologicalProcesspositive regulation of protein polymerization

PFN2 CLIP1 DRG1 TENM1 CTTN

4.23e-041021275GO:0032273
GeneOntologyBiologicalProcessresponse to axon injury

FLNA MORN4 NTRK3 P2RX4 MMP2

4.83e-041051275GO:0048678
GeneOntologyBiologicalProcessprotein autophosphorylation

DDR1 GRK7 NTRK2 GRK1 TXK EIF2AK2 EIF2AK3

5.35e-042281277GO:0046777
GeneOntologyBiologicalProcessregulation of membrane depolarization

ADCY10 CACNA1C P2RX7 RBFOX2

5.45e-04611274GO:0003254
GeneOntologyBiologicalProcessregulation of actin filament organization

FLNA PFN2 SHANK3 SPTBN5 TENM1 CTTN TACSTD2 HCLS1

5.48e-043001278GO:0110053
GeneOntologyBiologicalProcessregulation of protein polymerization

PFN2 CLIP1 DRG1 SPTBN5 TENM1 CTTN HCLS1

5.78e-042311277GO:0032271
GeneOntologyBiologicalProcessnegative regulation of apoptotic process

FLNA PCGF2 CAMK1D DOCK8 WNT1 NTRK2 DUSP1 CD2AP HIPK2 GRK1 SMG9 PRKCH CTTN EIF2AK2 EIF2AK3 HCLS1 RBFOX2

5.87e-04113312717GO:0043066
GeneOntologyBiologicalProcessregulation of calcium ion transport into cytosol

P2RX3 P2RX4 P2RX7

5.98e-04271273GO:0010522
GeneOntologyBiologicalProcessregulation of mitochondrial depolarization

ADCY10 P2RX7 RBFOX2

5.98e-04271273GO:0051900
GeneOntologyBiologicalProcesspositive regulation of organic acid transport

TNFSF11 P2RX4 P2RX7 ABCB11

6.17e-04631274GO:0032892
GeneOntologyBiologicalProcessneuronal action potential

P2RX1 P2RX3 P2RX4 P2RX7

6.17e-04631274GO:0019228
GeneOntologyBiologicalProcessregulation of actin cytoskeleton organization

FLNA CD2AP PFN2 SHANK3 SPTBN5 TENM1 CTTN TACSTD2 HCLS1

6.29e-043841279GO:0032956
GeneOntologyBiologicalProcesspositive regulation of response to external stimulus

FLNA CAMK1D NTRK3 COLEC10 WNK1 IFI35 TXK TNFSF11 P2RX4 BTK CTTN PSPC1 EIF2AK2

6.35e-0473812713GO:0032103
GeneOntologyBiologicalProcessregulation of translation in response to stress

PRKCH EIF2AK2 EIF2AK3

6.67e-04281273GO:0043555
GeneOntologyBiologicalProcesspositive regulation of protein localization to nucleus

FLNA CD2AP CCT5 EIF2AK3 HCLS1

7.03e-041141275GO:1900182
GeneOntologyBiologicalProcesspositive regulation of fatty acid transport

TNFSF11 P2RX4 P2RX7

7.41e-04291273GO:2000193
GeneOntologyBiologicalProcessregulation of icosanoid secretion

TNFSF11 P2RX4 P2RX7

7.41e-04291273GO:0032303
GeneOntologyBiologicalProcessnegative regulation of ruffle assembly

PFN2 TACSTD2

7.74e-0471272GO:1900028
GeneOntologyBiologicalProcessregulation of muscle system process

ADCY10 DOCK4 CACNA1C GTF2IRD2B P2RX1 P2RX4 GTF2IRD2 CTTN

7.85e-043171278GO:0090257
GeneOntologyBiologicalProcesspositive regulation of protein transport

CACNA1C FLNA CD2AP PFKM MALRD1 P2RX7 TENM1 HCLS1

8.18e-043191278GO:0051222
GeneOntologyBiologicalProcessnegative regulation of programmed cell death

FLNA PCGF2 CAMK1D DOCK8 WNT1 NTRK2 DUSP1 CD2AP HIPK2 GRK1 SMG9 PRKCH CTTN EIF2AK2 EIF2AK3 HCLS1 RBFOX2

8.48e-04117112717GO:0043069
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection assembly

RAP1GAP WNT1 PFN2 P2RX4 P2RX7 TENM1 TACSTD2

8.78e-042481277GO:0120032
GeneOntologyBiologicalProcessregulation of postsynaptic membrane potential

SHANK3 P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

8.78e-041801276GO:0060078
GeneOntologyBiologicalProcessvasoconstriction

DOCK4 CACNA1C P2RX1 MMP2 RBFOX2

9.19e-041211275GO:0042310
GeneOntologyBiologicalProcessmembrane depolarization

ADCY10 CACNA1C P2RX4 P2RX7 RBFOX2

9.19e-041211275GO:0051899
GeneOntologyBiologicalProcessregulation of blood circulation

ADCY10 DOCK4 CACNA1C FLNA P2RX1 P2RX4 MMP2 RBFOX2

9.41e-043261278GO:1903522
GeneOntologyBiologicalProcesspositive regulation of cellular component biogenesis

FLNA WNT1 NTRK2 NTRK3 PFN2 CLIP1 DRG1 P2RX7 BTK TENM1 CTTN

9.54e-0458212711GO:0044089
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

ADCY10 FLNA DDR1 CAMK1D WNT1 NTRK2 NTRK3 CLIP1 P2RX7 TENM1

9.75e-0449412710GO:0031346
GeneOntologyBiologicalProcessregulation of ruffle assembly

PFN2 P2RX4 TACSTD2

9.92e-04321273GO:1900027
GeneOntologyBiologicalProcesseiF2alpha phosphorylation in response to endoplasmic reticulum stress

EIF2AK2 EIF2AK3

1.03e-0381272GO:0036492
GeneOntologyBiologicalProcessregulation of translation initiation in response to endoplasmic reticulum stress

EIF2AK2 EIF2AK3

1.03e-0381272GO:0036491
GeneOntologyCellularComponentactin cytoskeleton

FLNA MYL1 CDC42BPA MYLK CD2AP CDC42BPB SLC2A1 SPTBN5 MST1R SH3PXD2A MYL6B CTTN HCLS1

5.86e-0557612913GO:0015629
GeneOntologyCellularComponenttranslation release factor complex

GSPT1 GSPT2

1.13e-0431292GO:0018444
GeneOntologyCellularComponentterminal bouton

NTRK2 P2RX3 P2RX4 P2RX7 SYNJ1

3.23e-04961295GO:0043195
GeneOntologyCellularComponentphotoreceptor disc membrane

GRK7 GRK1 SPTBN5

5.38e-04261293GO:0097381
GeneOntologyCellularComponentdendrite

ADCY10 CACNA1C FLNA RAP1GAP NTRK2 CD2AP SHANK3 SLC12A5 CNNM1 P2RX3 P2RX4 SACS P2RX6 CTTN

8.51e-0485812914GO:0030425
GeneOntologyCellularComponentdendritic tree

ADCY10 CACNA1C FLNA RAP1GAP NTRK2 CD2AP SHANK3 SLC12A5 CNNM1 P2RX3 P2RX4 SACS P2RX6 CTTN

8.71e-0486012914GO:0097447
HumanPhenoMitral valve prolapse

FLNA PCGF2 LZTR1 VWF SACS GTF2IRD2 MMP2 TBL2 BICC1

7.05e-06123579HP:0001634
HumanPhenoAbnormal mitral valve morphology

FLNA PCGF2 LZTR1 VWF SACS GTF2IRD2 MMP2 TBL2 BICC1

2.84e-05146579HP:0031477
MousePhenoabnormal pain threshold

SEMA6C CACNA1C RARS1 SHANK3 PRX SLC12A5 P2RX3 CLCN6 P2RX7 P2RX6

3.20e-0526710510MP:0001970
MousePhenoabnormal thermal nociception

SEMA6C RARS1 SHANK3 PRX SLC12A5 P2RX3 CLCN6 P2RX6

3.82e-051681058MP:0002733
MousePhenohypoalgesia

CACNA1C RARS1 SHANK3 PRX SLC12A5 P2RX3 CLCN6 P2RX6

4.15e-051701058MP:0003043
DomainP2X_receptor

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

3.02e-1071295PF00864
DomainP2X_purnocptor

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

3.02e-1071295IPR001429
Domain-

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

3.02e-10712952.60.490.10
DomainP2X_RECEPTOR

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

3.02e-1071295PS01212
DomainP2X_extracellular_dom

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

3.02e-1071295IPR027309
DomainPROTEIN_KINASE_ATP

CDC42BPG DDR1 CDC42BPA CAMK1D MYLK GRK7 NTRK2 NTRK3 HIPK2 WNK1 CDC42BPB GRK1 TXK MST1R BTK PRKCH EIF2AK2 EIF2AK3

2.75e-0945912918PS00107
DomainProt_kinase_dom

CDC42BPG DDR1 CDC42BPA CAMK1D MYLK GRK7 NTRK2 NTRK3 HIPK2 WNK1 CDC42BPB GRK1 TXK MST1R BTK PRKCH EIF2AK2 EIF2AK3

7.40e-0948912918IPR000719
DomainProtein_kinase_ATP_BS

CDC42BPG CDC42BPA CAMK1D MYLK GRK7 NTRK2 NTRK3 HIPK2 CDC42BPB GRK1 TXK MST1R BTK PRKCH EIF2AK2 EIF2AK3

7.99e-0937912916IPR017441
DomainPROTEIN_KINASE_DOM

CDC42BPG DDR1 CDC42BPA CAMK1D MYLK GRK7 NTRK2 NTRK3 HIPK2 WNK1 CDC42BPB GRK1 TXK MST1R BTK PRKCH EIF2AK2 EIF2AK3

8.39e-0949312918PS50011
DomainKinase-like_dom

CDC42BPG DDR1 CDC42BPA CAMK1D MYLK GRK7 NTRK2 NTRK3 HIPK2 WNK1 CDC42BPB GRK1 TXK MST1R BTK PRKCH EIF2AK2 EIF2AK3

3.59e-0854212918IPR011009
DomainMyotonic_dystrophy_kinase_coil

CDC42BPG CDC42BPA CDC42BPB

1.28e-0641293IPR014930
DomainMyotonic_dystrophy_kinase_coil

CDC42BPG CDC42BPA CDC42BPB

1.28e-0641293PD011252
DomainDMPK_coil

CDC42BPG CDC42BPA CDC42BPB

1.28e-0641293PF08826
DomainAGC-kinase_C

CDC42BPG CDC42BPA GRK7 CDC42BPB GRK1 PRKCH

2.36e-06561296IPR000961
DomainAGC_KINASE_CTER

CDC42BPG CDC42BPA GRK7 CDC42BPB GRK1 PRKCH

2.36e-06561296PS51285
DomainS_TK_X

CDC42BPG CDC42BPA GRK7 CDC42BPB GRK1 PRKCH

2.36e-06561296SM00133
DomainSer/Thr_kinase_AS

CDC42BPG CDC42BPA CAMK1D MYLK GRK7 HIPK2 WNK1 CDC42BPB GRK1 PRKCH EIF2AK2 EIF2AK3

6.97e-0635712912IPR008271
DomainS_TKc

CDC42BPG CDC42BPA CAMK1D MYLK GRK7 HIPK2 WNK1 CDC42BPB GRK1 PRKCH EIF2AK2 EIF2AK3

7.37e-0635912912SM00220
DomainPROTEIN_KINASE_ST

CDC42BPG CDC42BPA CAMK1D MYLK GRK7 HIPK2 WNK1 CDC42BPB GRK1 PRKCH EIF2AK2 EIF2AK3

8.02e-0636212912PS00108
DomainPkinase

CDC42BPG CDC42BPA CAMK1D MYLK GRK7 HIPK2 WNK1 CDC42BPB GRK1 PRKCH EIF2AK2 EIF2AK3

1.34e-0538112912PF00069
DomainTyr_kinase_cat_dom

DDR1 NTRK2 NTRK3 TXK MST1R BTK

3.29e-05881296IPR020635
DomainTyrKc

DDR1 NTRK2 NTRK3 TXK MST1R BTK

3.29e-05881296SM00219
DomainCORTACTIN

CTTN HCLS1

4.73e-0521292PS51090
DomainCXorf40

EOLA1 EOLA2

4.73e-0521292IPR033615
DomainKELK

CDC42BPA CDC42BPB

4.73e-0521292IPR031597
DomainKELK

CDC42BPA CDC42BPB

4.73e-0521292PF15796
DomainHS1_rep

CTTN HCLS1

4.73e-0521292PF02218
DomainHs1_Cortactin

CTTN HCLS1

4.73e-0521292IPR003134
DomainTyr_kinase_rcpt_2_CS

DDR1 NTRK2 NTRK3

5.10e-05111293IPR002011
DomainPROTEIN_KINASE_TYR

DDR1 NTRK2 NTRK3 TXK MST1R BTK

5.71e-05971296PS00109
DomainTyr_kinase_AS

DDR1 NTRK2 NTRK3 TXK MST1R BTK

5.71e-05971296IPR008266
DomainRECEPTOR_TYR_KIN_II

DDR1 NTRK2 NTRK3

6.77e-05121293PS00239
DomainCNH

CDC42BPG CDC42BPA CDC42BPB

1.11e-04141293SM00036
DomainPkinase_C

CDC42BPG CDC42BPA CDC42BPB PRKCH

1.20e-04371294IPR017892
DomainSH3

DOCK4 CD2AP SHANK3 TXK SH3PXD2A BTK CTTN HCLS1

1.29e-042161298SM00326
DomainSH3

DOCK4 CD2AP SHANK3 TXK SH3PXD2A BTK CTTN HCLS1

1.29e-042161298PS50002
DomainCNH

CDC42BPG CDC42BPA CDC42BPB

1.38e-04151293PF00780
DomainCNH

CDC42BPG CDC42BPA CDC42BPB

1.38e-04151293PS50219
DomainCNH_dom

CDC42BPG CDC42BPA CDC42BPB

1.38e-04151293IPR001180
DomainASCH_domain

EOLA1 EOLA2

1.41e-0431292IPR007374
DomainFox-1_C

RBFOX1 RBFOX2

1.41e-0431292PF12414
DomainASCH

EOLA1 EOLA2

1.41e-0431292SM01022
DomainFox-1_C_dom

RBFOX1 RBFOX2

1.41e-0431292IPR025670
DomainTPKR_C2

NTRK2 NTRK3

1.41e-0431292PF16920
DomainTyr_kinase_NGF_rcpt

NTRK2 NTRK3

1.41e-0431292IPR020777
DomainNTRK_C2

NTRK2 NTRK3

1.41e-0431292IPR031635
DomainRNA-bd_Fox-1

RBFOX1 RBFOX2

1.41e-0431292IPR017325
DomainSH3_domain

DOCK4 CD2AP SHANK3 TXK SH3PXD2A BTK CTTN HCLS1

1.47e-042201298IPR001452
DomainPkinase_C

CDC42BPG CDC42BPA CDC42BPB PRKCH

1.98e-04421294PF00433
DomainPkinase_Tyr

DDR1 NTRK2 NTRK3 TXK MST1R BTK

2.75e-041291296PF07714
Domain-

GTF2IRD2B GTF2IRD2

2.81e-04412923.90.1460.10
DomainGTF2I

GTF2IRD2B GTF2IRD2

2.81e-0441292PS51139
DomainGTF2I

GTF2IRD2B GTF2IRD2

2.81e-0441292PF02946
DomainGTF2I

GTF2IRD2B GTF2IRD2

2.81e-0441292IPR004212
DomainVWC_out

FRAS1 VWF ZAN

2.88e-04191293SM00215
DomainCRIB

CDC42BPG CDC42BPA CDC42BPB

3.37e-04201293PS50108
DomainCRIB_dom

CDC42BPG CDC42BPA CDC42BPB

3.91e-04211293IPR000095
DomainSer-Thr/Tyr_kinase_cat_dom

DDR1 NTRK2 NTRK3 TXK MST1R BTK

3.94e-041381296IPR001245
DomainC1_1

CDC42BPG CDC42BPA CDC42BPB PRKCH

6.46e-04571294PF00130
DomainGPCR_kinase

GRK7 GRK1

9.72e-0471292IPR000239
DomainSH3_1

CD2AP TXK SH3PXD2A BTK CTTN HCLS1

9.78e-041641296PF00018
DomainZF_DAG_PE_1

CDC42BPG CDC42BPA CDC42BPB PRKCH

1.00e-03641294PS00479
DomainZF_DAG_PE_2

CDC42BPG CDC42BPA CDC42BPB PRKCH

1.00e-03641294PS50081
DomainC1

CDC42BPG CDC42BPA CDC42BPB PRKCH

1.06e-03651294SM00109
DomainPE/DAG-bd

CDC42BPG CDC42BPA CDC42BPB PRKCH

1.12e-03661294IPR002219
DomainTransl_elong_EFTu/EF1A_C

GSPT1 GSPT2

1.29e-0381292IPR004160
DomainGTP_EFTU_D3

GSPT1 GSPT2

1.29e-0381292PF03143
DomainG_TR_CS

GSPT1 GSPT2

1.65e-0391292IPR031157
DomainVWFC_1

FRAS1 VWF ZAN

1.95e-03361293PS01208
DomainTransl_elong_EF1A/Init_IF2_C

GSPT1 GSPT2

2.05e-03101292IPR009001
DomainVWFC_2

FRAS1 VWF ZAN

2.28e-03381293PS50184
DomainVWC

FRAS1 VWF ZAN

2.28e-03381293SM00214
DomainDHR-1_domain

DOCK4 DOCK8

2.50e-03111292IPR027007
DomainDHR_2

DOCK4 DOCK8

2.50e-03111292PS51651
DomainDHR_1

DOCK4 DOCK8

2.50e-03111292PS51650
DomainDHR-2

DOCK4 DOCK8

2.50e-03111292PF06920
DomainDOCK

DOCK4 DOCK8

2.50e-03111292IPR026791
DomainDOCK_C

DOCK4 DOCK8

2.50e-03111292IPR010703
DomainDOCK-C2

DOCK4 DOCK8

2.50e-03111292PF14429
DomainDHR-2

DOCK4 DOCK8

2.50e-03111292IPR027357
DomainC8

VWF ZAN

2.99e-03121292PF08742
DomainTIL

VWF ZAN

2.99e-03121292PF01826
DomainVWF_dom

FRAS1 VWF ZAN

3.04e-03421293IPR001007
DomainG_TR_1

GSPT1 GSPT2

3.51e-03131292PS00301
DomainUnchr_dom_Cys-rich

VWF ZAN

3.51e-03131292IPR014853
DomainC8

VWF ZAN

3.51e-03131292SM00832
DomainTIL_dom

VWF ZAN

4.08e-03141292IPR002919
DomainGROEL-like_equatorial

CCT5 BBS12

4.08e-03141292IPR027413
Domain-

CCT5 BBS12

4.08e-031412921.10.560.10
DomainGroEL-like_apical_dom

CCT5 BBS12

4.69e-03151292IPR027409
DomainCpn60/TCP-1

CCT5 BBS12

4.69e-03151292IPR002423
DomainCpn60_TCP1

CCT5 BBS12

4.69e-03151292PF00118
Domain-

CCT5 BBS12

4.69e-031512923.50.7.10
DomainPH

CDC42BPG CDC42BPA CDC42BPB SPTBN5 CADPS BTK

5.18e-032291296PF00169
DomainCBS

CNNM1 CLCN6

5.33e-03161292SM00116
DomainVWF_type-D

VWF ZAN

5.33e-03161292IPR001846
DomainVWFD

VWF ZAN

5.33e-03161292PS51233
DomainVWD

VWF ZAN

5.33e-03161292SM00216
DomainPBD

CDC42BPA CDC42BPB

5.33e-03161292SM00285
DomainVWD

VWF ZAN

5.33e-03161292PF00094
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_LIGAND_GATED_CA2_CHANNEL

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

1.30e-08121015M47953
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

2.10e-08131015MM14553
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

7.01e-08161015M26945
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

1.22e-06271015MM15053
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

1.47e-06281015M924
PathwayWP_PURINERGIC_SIGNALING

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

3.46e-06331015M39855
PathwayREACTOME_PLATELET_HOMEOSTASIS

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

2.11e-04761015MM15051
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1C MYLK P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

2.88e-041781017M2890
PathwayREACTOME_PLATELET_HOMEOSTASIS

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

3.76e-04861015M916
PathwayREACTOME_RHO_GTPASES_ACTIVATE_PAKS

FLNA MYLK CTTN

4.32e-04211013M27494
Pubmed

Update of P2X receptor properties and their pharmacology: IUPHAR Review 30.

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

1.41e-117130533125712
Pubmed

Membrane compartments and purinergic signalling: occurrence and function of P2X receptors in lung.

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

1.41e-117130519076210
Pubmed

ATP-gated P2X cation-channels.

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

1.41e-117130518657557
Pubmed

Go it alone no more--P2X7 joins the society of heteromeric ATP-gated receptor channels.

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

1.41e-117130517895406
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

PCGF2 CDC42BPA CAMK1D MYLK MTHFD2 GRK7 USP24 HIPK2 WNK1 CDC42BPB GSPT1 GRK1 METAP1 ENTPD2 PRKCH PPIL2 MMP2 PSPC1

2.91e-107301301834857952
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

DOCK4 FLNA CDC42BPA MORN4 RARS1 KIAA0513 ACADVL NTRK2 USP24 PFN2 CDC42BPB SHANK3 GSPT2 SYNJ1 CCT5 HNRNPUL2 CADPS TENM1 CTTN HSPA2 FAM177A1

1.63e-0911391302136417873
Pubmed

Molecular physiology of P2X receptors.

P2RX1 P2RX3 P2RX4 P2RX7

2.78e-096130412270951
Pubmed

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.

ACADVL PFN2 WNK1 CDC42BPB SLC2A1 SYNJ1 CCT5 SACS SH3PXD2A STEEP1

1.75e-082301301035449600
Pubmed

Functional evidence for the expression of P2X1, P2X4 and P2X7 receptors in human lung mast cells.

P2RX1 P2RX4 P2RX7

5.10e-083130319552691
Pubmed

Ambulatory blood pressure is associated with polymorphic variation in P2X receptor genes.

P2RX4 P2RX7 P2RX6

5.10e-083130318852390
Pubmed

Functional expression of P2X1, P2X4 and P2X7 purinergic receptors in human monocyte-derived macrophages.

P2RX1 P2RX4 P2RX7

5.10e-083130332805257
Pubmed

Lipid raft association and cholesterol sensitivity of P2X1-4 receptors for ATP: chimeras and point mutants identify intracellular amino-terminal residues involved in lipid regulation of P2X1 receptors.

P2RX1 P2RX3 P2RX4

2.04e-074130320699225
Pubmed

ATP augments von Willebrand factor-dependent shear-induced platelet aggregation through Ca2+-calmodulin and myosin light chain kinase activation.

VWF MYLK P2RX1

2.04e-074130315087444
Pubmed

Subtype-specific control of P2X receptor channel signaling by ATP and Mg2+.

P2RX1 P2RX3 P2RX4

2.04e-074130323959888
Pubmed

A human MAP kinase interactome.

FLNA EXOSC9 VWF CDC42BPA DUSP1 HIPK2 ITPRID2 WNK1 CDC42BPB BTK PRKCH RBFOX2

3.15e-074861301220936779
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

FLNA RAP1GAP VWF DOCK8 PFKM PFN2 CDC42BPB SHANK3 SLC2A1 SLC12A5 P2RX3 CLCN6 SYNJ1 CCT5 SACS HNRNPUL2 CADPS CTTN PSPC1 HSPA2

3.79e-0714311302037142655
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CACNA1C FLNA MYLK PCDHGB6 ACADVL PFKM PRX GSPT1 GTF2IRD2B GSPT2 SACS SH3PXD2A TCHHL1 ENTPD2 GTF2IRD2 TENM1 CTTN PSPC1 HSPA2 HCLS1

4.28e-0714421302035575683
Pubmed

Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins.

CACNA1C RBFOX1 RBFOX2

5.08e-075130319564422
Pubmed

P2X1, P2X4, and P2X7 Receptor Knock Out Mice Expose Differential Outcome of Sepsis Induced by α-Haemolysin Producing Escherichia coli.

P2RX1 P2RX4 P2RX7

5.08e-075130328428949
Pubmed

The protein tyrosine kinase family of the human genome.

DDR1 NTRK2 NTRK3 TXK MST1R BTK

7.24e-0783130611114734
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA6C FLNA FRAS1 LZTR1 CDC42BPA KIAA0513 MYOM3 MED14 WNK1 CDC42BPB SLC2A1 FAM83H MST1R SYNJ1 ENTPD2 ZFYVE26 RIC1

8.47e-0711051301735748872
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1C P2RX1 P2RX3 P2RX4 CLCN6 P2RX7 P2RX6

9.81e-07139130716985003
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

DDR1 HECTD3 GRK7 NTRK2 NTRK3 BTK GTF2IRD2 PRKCH EIF2AK2 HERC4

1.48e-063721301022939624
Pubmed

MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion.

CDC42BPG CDC42BPA CDC42BPB

1.77e-067130329162624
Pubmed

Functional genomics identifies therapeutic targets for MYC-driven cancer.

MYLK HECTD3 WNK1 GRK1 TXK BTK

2.58e-06103130622623531
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

CDC42BPG PTGES2 HECTD3 USP24 METAP1 HERC4 VPS53

6.10e-06183130731932471
Pubmed

Normal Molecular Specification and Neurodegenerative Disease-Like Death of Spinal Neurons Lacking the SNARE-Associated Synaptic Protein Munc18-1.

CACNA1C NTRK2 NTRK3 ETV4

6.18e-0632130426758845
Pubmed

A Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton.

CD2AP SH3PXD2A CTTN

1.10e-0512130312672817
Pubmed

Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.

FLNA CLIP1 RBFOX1 CTTN

1.12e-0537130427565344
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SLC25A24 EXOSC9 CDC42BPA RARS1 CD2AP MED14 ITPRID2 CDC42BPB SLC2A1 DRG1 METAP1 CCT5 SLC4A1AP METTL18 PSPC1 TACSTD2 EIF2AK2 TBL2

1.22e-0514971301831527615
Pubmed

PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria.

ACADVL SLC2A1 CCT5 PRKCH CTTN TACSTD2

1.28e-05136130622304920
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

FLNA MYL1 RARS1 MTHFD2 ITPRID2 GSPT2 CCT5 HNRNPUL2 MYL6B STEEP1 PPIL2 CTTN HSPA2 EIF2AK2

1.35e-059491301436574265
Pubmed

Comprehensive analysis of two Shank3 and the Cacna1c mouse models of autism spectrum disorder.

CACNA1C SHANK3

1.39e-052130228753255
Pubmed

Potential Involvement of P2 Receptors in the Pathological Processes of Hyperthyroidism: A Pilot Study.

P2RX3 P2RX7

1.39e-052130227312548
Pubmed

Abnormal development of pacinian corpuscles in double trkB;trkC knockout mice.

NTRK2 NTRK3

1.39e-052130217101216
Pubmed

P2X7/P2X4 Receptors Mediate Proliferation and Migration of Retinal Microglia in Experimental Glaucoma in Mice.

P2RX4 P2RX7

1.39e-052130235254644
Pubmed

Mechanisms of activation and repression by the alternative splicing factors RBFOX1/2.

RBFOX1 RBFOX2

1.39e-052130222184459
Pubmed

Repression of prespliceosome complex formation at two distinct steps by Fox-1/Fox-2 proteins.

RBFOX1 RBFOX2

1.39e-052130218573872
Pubmed

Molecular characterization and pharmacological properties of the human P2X3 purinoceptor.

P2RX3 P2RX4

1.39e-05213029221902
Pubmed

Mapping of the tyrosine kinase receptors trkA (NTRK1), trkB (NTRK2) and trkC(NTRK3) to human chromosomes 1q22, 9q22 and 15q25 by fluorescence in situ hybridization.

NTRK2 NTRK3

1.39e-05213029195161
Pubmed

Involvement of human release factors eRF3a and eRF3b in translation termination and regulation of the termination complex formation.

GSPT1 GSPT2

1.39e-052130215987998
Pubmed

Coexpression of glucose transporter 1 and matrix metalloproteinase-2 in human cancers.

SLC2A1 MMP2

1.39e-052130212122099
Pubmed

Distinct contributions by ionotropic purinoceptor subtypes to ATP-evoked calcium signals in mouse parotid acinar cells.

P2RX4 P2RX7

1.39e-052130222451435
Pubmed

A rare functional haplotype of the P2RX4 and P2RX7 genes leads to loss of innate phagocytosis and confers increased risk of age-related macular degeneration.

P2RX4 P2RX7

1.39e-052130223303206
Pubmed

The TrkB-positive dopaminergic neurons are less sensitive to MPTP insult in the substantia nigra of adult C57/BL mice.

NTRK2 NTRK3

1.39e-052130221562748
Pubmed

Cloning and chromosomal localization of human Cdc42-binding protein kinase beta.

CDC42BPA CDC42BPB

1.39e-052130210198171
Pubmed

Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue.

P2RX3 P2RX4

1.39e-05213029016352
Pubmed

Characterization of CaV1.2 exon 33 heterozygous knockout mice and negative correlation between Rbfox1 and CaV1.2 exon 33 expressions in human heart failure.

CACNA1C RBFOX1

1.39e-052130228949795
Pubmed

Rbfox-Splicing Factors Maintain Skeletal Muscle Mass by Regulating Calpain3 and Proteostasis.

RBFOX1 RBFOX2

1.39e-052130229972780
Pubmed

Vascular smooth muscle cells from small human omental arteries express P2X1 and P2X4 receptor subunits.

P2RX1 P2RX4

1.39e-052130224845338
Pubmed

MKP-1 is essential for canonical vitamin D-induced signaling through nuclear import and regulates RANKL expression and function.

DUSP1 TNFSF11

1.39e-052130222899855
Pubmed

Functional interactions between P2X4 and P2X7 receptors from mouse salivary epithelia.

P2RX4 P2RX7

1.39e-052130219403602
Pubmed

GABAA receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl--sensitive WNK1 kinase.

WNK1 SLC12A5

1.39e-052130229176664
Pubmed

CD2AP links cortactin and capping protein at the cell periphery to facilitate formation of lamellipodia.

CD2AP CTTN

1.39e-052130223090967
Pubmed

The endoplasmic reticulum-localized protein TBL2 interacts with the 60S ribosomal subunit.

EIF2AK3 TBL2

1.39e-052130225976671
Pubmed

P2X1 and P2X4 receptor currents in mouse macrophages.

P2RX1 P2RX4

1.39e-052130217934511
Pubmed

P2X4 and P2X7 are essential players in basal T cell activity and Ca2+ signaling milliseconds after T cell activation.

P2RX4 P2RX7

1.39e-052130235119925
Pubmed

Tissue-dependent isoforms of mammalian Fox-1 homologs are associated with tissue-specific splicing activities.

RBFOX1 RBFOX2

1.39e-052130215824060
Pubmed

Characterization and mechanism of P2X receptor-mediated increase in cardiac myocyte contractility.

P2RX1 P2RX4

1.39e-052130217873021
Pubmed

von Willebrand Factor and Prekallikrein in Plasma Are Associated With Thrombus Volume in Abdominal Aortic Aneurysms.

VWF KLKB1

1.39e-052130227581227
Pubmed

TrkB but not trkC receptors are necessary for postnatal maintenance of hippocampal spines.

NTRK2 NTRK3

1.39e-052130217442456
Pubmed

Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta.

CDC42BPA CDC42BPB

1.39e-052130218263588
Pubmed

Involvement of P2X4 receptor in P2X7 receptor-dependent cell death of mouse macrophages.

P2RX4 P2RX7

1.39e-052130222349510
Pubmed

Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase.

MYLK CTTN

1.39e-052130215056655
Pubmed

P2X currents in peritoneal macrophages of wild type and P2X4 -/- mice.

P2RX4 P2RX7

1.39e-052130217825926
Pubmed

Selective activation and down-regulation of Trk receptors by neurotrophins in human neurons co-expressing TrkB and TrkC.

NTRK2 NTRK3

1.39e-052130235536742
Pubmed

A tale of two kinases in rods and cones.

GRK7 GRK1

1.39e-052130222183412
Pubmed

Haploinsufficiency in trkB and/or trkC neurotrophin receptors causes structural alterations in the aged hippocampus and amygdala.

NTRK2 NTRK3

1.39e-052130214622193
Pubmed

The ATP Receptors P2X7 and P2X4 Modulate High Glucose and Palmitate-Induced Inflammatory Responses in Endothelial Cells.

P2RX4 P2RX7

1.39e-052130225938443
Pubmed

Severe sensory deficits but normal CNS development in newborn mice lacking TrkB and TrkC tyrosine protein kinase receptors.

NTRK2 NTRK3

1.39e-05213029421165
Pubmed

The combined effects of trkB and trkC mutations on the innervation of the inner ear.

NTRK2 NTRK3

1.39e-05213029881298
Pubmed

Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms.

NTRK2 NTRK3

1.39e-052130232315394
Pubmed

Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2.

RBFOX1 RBFOX2

1.39e-052130218794351
Pubmed

Role of purinergic receptors in hepatobiliary carcinoma in Pakistani population: an approach towards proinflammatory role of P2X4 and P2X7 receptors.

P2RX4 P2RX7

1.39e-052130231401785
Pubmed

Reversible inhibition of Chlamydia trachomatis infection in epithelial cells due to stimulation of P2X(4) receptors.

P2RX4 P2RX7

1.39e-052130222988022
Pubmed

Lack of TrkB and TrkC signaling alters the synaptogenesis and maturation of mossy fiber terminals in the hippocampus.

NTRK2 NTRK3

1.39e-052130215726425
Pubmed

Trop2 enhances invasion of thyroid cancer by inducing MMP2 through ERK and JNK pathways.

MMP2 TACSTD2

1.39e-052130228709407
Pubmed

Purinergic receptors P2RX4 and P2RX7 in familial multiple sclerosis.

P2RX4 P2RX7

1.39e-052130228326637
Pubmed

Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK.

EIF2AK2 EIF2AK3

1.39e-052130212610133
Pubmed

Phosphorylation of GRK1 and GRK7 by cAMP-dependent protein kinase attenuates their enzymatic activities.

GRK7 GRK1

1.39e-052130215946941
Pubmed

Atypical P2X receptor pharmacology in two human osteoblast-like cell lines.

P2RX4 P2RX7

1.39e-052130219226284
Pubmed

P2X7R and P2X4R expression of mice submandibular gland in high-fat diet/streptozotocin-induced type 2 diabetes.

P2RX4 P2RX7

1.39e-052130238740782
Pubmed

WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons.

WNK1 SLC12A5

1.39e-052130226126716
Pubmed

Differential regulation of microglial P2X4 and P2X7 ATP receptors following LPS-induced activation.

P2RX4 P2RX7

1.39e-052130217675190
Pubmed

P2X(1) and P2X(3) purinergic receptors differentially modulate the inflammatory response in human osteoarthritic synovial fibroblasts.

P2RX1 P2RX3

1.39e-052130220110693
Pubmed

Tropomyosin receptor kinases B and C are tumor progressive and metastatic marker in colorectal carcinoma.

NTRK2 NTRK3

1.39e-052130223332094
Pubmed

Novel interaction of cortactin with endothelial cell myosin light chain kinase.

MYLK CTTN

1.39e-052130212408982
Pubmed

A common cortactin gene variation confers differential susceptibility to severe asthma.

MYLK CTTN

1.39e-052130218521921
Pubmed

Analysis of assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells.

P2RX4 P2RX7

1.39e-052130219304656
Pubmed

P2X4 receptor regulates P2X7 receptor-dependent IL-1β and IL-18 release in mouse bone marrow-derived dendritic cells.

P2RX4 P2RX7

1.39e-052130223428419
Pubmed

The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling.

FLNA EIF2AK3

1.39e-052130228238652
Pubmed

Conditional deletion of TrkC does not modify limbic epileptogenesis.

NTRK2 NTRK3

1.39e-052130222980123
Pubmed

Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domain.

CTTN HCLS1

1.39e-052130215710041
Pubmed

Evidence for functional P2X4/P2X7 heteromeric receptors.

P2RX4 P2RX7

1.39e-052130217785580
Pubmed

Rbfox proteins regulate tissue-specific alternative splicing of Mef2D required for muscle differentiation.

RBFOX1 RBFOX2

1.39e-052130225609712
Pubmed

Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons.

NTRK2 NTRK3

1.39e-052130211877382
Pubmed

Frequent mutations in the neurotrophic tyrosine receptor kinase gene family in large cell neuroendocrine carcinoma of the lung.

NTRK2 NTRK3

1.39e-052130218293376
Pubmed

Different localization of P2X4 and P2X7 receptors in native mouse lung - lack of evidence for a direct P2X4-P2X7 receptor interaction.

P2RX4 P2RX7

1.39e-052130238953020
Pubmed

Rbfox proteins regulate alternative splicing of neuronal sodium channel SCN8A.

RBFOX1 RBFOX2

1.39e-052130222044765
Pubmed

The eIF2alpha kinases PERK and PKR activate glycogen synthase kinase 3 to promote the proteasomal degradation of p53.

EIF2AK2 EIF2AK3

1.39e-052130217785458
InteractionMYO6 interactions

FLNA DOCK8 NTRK2 NTRK3 CD2AP USP25 PFN2 SLC2A1 SYNJ1 MYL6B ARL13B CTTN

7.06e-0639812512int:MYO6
InteractionGRB2 interactions

DOCK4 FLNA RARS1 NTRK2 NTRK3 CD2AP SHANK3 DRG1 TXK MST1R SYNJ1 CCT5 SH3PXD2A BTK CTTN PSPC1 HCLS1

1.01e-0580612517int:GRB2
Cytoband12p13.3

CACNA1C VWF WNK1

8.52e-0530130312p13.3
GeneFamilyPurinergic receptors P2X

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

1.81e-117725214
GeneFamilyReceptor Tyrosine Kinases|CD molecules

DDR1 NTRK2 NTRK3 MST1R

1.90e-0540724321
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MYLK NTRK2 NTRK3 MYOM3 LRIT1

4.55e-04161725593
GeneFamilyMyosin light chains|EF-hand domain containing

MYL1 MYL6B

1.38e-0314722657
GeneFamilyChaperonins

CCT5 BBS12

1.59e-0315722587
CoexpressionONKEN_UVEAL_MELANOMA_UP

DOCK4 RAP1GAP PCGF2 CDC42BPA ACADVL PFN2 CLIP1 CDC42BPB GSPT1 SACS MMP2 CTTN PSPC1 TBL2 HCLS1 RBFOX2

1.98e-0679013016M12490
CoexpressionGSE15930_STIM_VS_STIM_AND_IL12_24H_CD8_T_CELL_DN

SEMA6C RARS1 GSPT2 P2RX6 MYL6B METTL18 TENM1 RBFOX2

7.06e-061991308M3622
CoexpressionLAKE_ADULT_KIDNEY_C27_VASCULAR_SMOOTH_MUSCLE_CELLS_AND_PERICYTES

DOCK4 CACNA1C FLNA CDC42BPA MYLK DUSP1 NTRK3

1.27e-051551307M39246
CoexpressionLEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP

DDR1 LZTR1 HIPK2 WNK1 BTK

3.40e-05741305M515
CoexpressionGSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_DN

EXOSC9 RARS1 CLIP1 B4GALT5 TNFSF11 CADPS PRKCH

6.29e-051991307M3313
CoexpressionGSE29164_DAY3_VS_DAY7_UNTREATED_MELANOMA_DN

SLC25A24 CAMK1D HIPK2 CLCN6 P2RX7 ZFYVE26 BBS12

6.29e-051991307M8487
CoexpressionHALLMARK_IL2_STAT5_SIGNALING

HIPK2 ETV4 FAH TNFSF11 COCH P2RX4 PRKCH

6.29e-051991307M5947
CoexpressionGSE15330_WT_VS_IKAROS_KO_LYMPHOID_MULTIPOTENT_PROGENITOR_UP

ACADVL HECTD3 USP25 FAH ZFYVE26 HSPA2 HCLS1

6.49e-052001307M7037
CoexpressionGSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_DN

MTHFD2 USP25 IFI35 FAH COCH EIF2AK2 EIF2AK3

6.49e-052001307M3635
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADCY10 CACNA1C FRAS1 ZAN NTRK3 TENM1 ABCB11 KLKB1

2.66e-081621308bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-VSMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C FLNA ISYNA1 MYLK NTRK2 NTRK3 RBM20 HSPA2

7.75e-081861308c7885fd6dc7dc8fffc96f0112c51a365cf8a8f80
ToppCellControl-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

CACNA1C FLNA ISYNA1 MYLK NTRK2 NTRK3 RBM20 HSPA2

9.51e-0819113082da83c493e60ad0278848957645277d76737a188
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTHFD2 NTRK3 B4GALT5 P2RX1 RBFOX1 TACSTD2 BBS12

3.12e-071511307523dcd243c285a6b74830a93c82cca8784edd658
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTHFD2 NTRK3 B4GALT5 P2RX1 RBFOX1 TACSTD2 BBS12

3.12e-071511307f3406094ce79cc80398b82d58ca6fd87a96e68d4
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

CACNA1C FLNA MYLK DOCK8 MTHFD2 NTRK2 NTRK3

7.22e-071711307e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK4 FRAS1 NTRK2 HIPK2 SHANK3 PRX P2RX7

1.31e-061871307ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellCOPD-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

CACNA1C FLNA ISYNA1 MTHFD2 NTRK3 HIPK2 RBM20

1.36e-0618813079ffef4b01d0ddd6913c9ed6be79aeaaabd5e41ed
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

KIAA0513 SLC12A5 CNNM1 SYNJ1 CADPS RBFOX1 TENM1

1.57e-0619213074c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

DOCK4 VWF CD2AP HIPK2 SHANK3 B4GALT5 PRKCH

1.62e-0619313072531266bc57339d4e2b22a88817008e32b8c1598
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

CACNA1C FRAS1 CAMK1D NTRK2 RBM20 CADPS RBFOX1

1.68e-06194130789812fb164065041357bb37a3c2d87028ec3de4e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CAMK1D KIAA0513 DOCK8 P2RX1 P2RX7 BTK HCLS1

1.74e-0619513071d58585557bf8e9ce4d514e128d3a902b526331d
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNA1C VWF CDC42BPA SHANK3 RBM20 SLC2A1 RBFOX2

2.06e-062001307032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNA1C VWF CDC42BPA SHANK3 RBM20 SLC2A1 RBFOX2

2.06e-06200130768fce28690246895fd33354b30960ebcc31aa4cc
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNA1C VWF CDC42BPA SHANK3 RBM20 SLC2A1 RBFOX2

2.06e-062001307376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNA1C VWF CDC42BPA SHANK3 RBM20 SLC2A1 RBFOX2

2.06e-0620013077fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNA1C VWF CDC42BPA SHANK3 RBM20 SLC2A1 RBFOX2

2.06e-062001307878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCellHematolymphoid-Endothelial|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNA1C VWF CDC42BPA SHANK3 RBM20 SLC2A1 RBFOX2

2.06e-0620013077136936d05ab344a560cf159684c881063b5430d
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 TXK AGXT2 COCH BBS12 LRIT1

7.36e-0615913064000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 TXK AGXT2 COCH BBS12 LRIT1

7.36e-0615913067619d0d49738dd08daf01b42664691a5323aa793
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

CACNA1C FLNA MYLK DOCK8 MTHFD2 NTRK3

9.10e-061651306f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C FLNA ISYNA1 MYLK NTRK3 RBM20

9.10e-0616513068a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRAS1 TXK AGXT2 COCH BBS12 LRIT1

9.42e-061661306bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRAS1 TXK AGXT2 COCH BBS12 LRIT1

9.42e-0616613065e3b998d740b24f790fad37350d704ca0ea10b77
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA ISYNA1 MYLK MTHFD2 NTRK3 RBM20

1.19e-051731306fc2602b2ce051cd4c33957d7e3d041ff8a529883
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA ISYNA1 MYLK MTHFD2 NTRK3 RBM20

1.19e-051731306901b8e6909c1f3849906fad9cee17b8f0bab050d
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NTRK3 B4GALT5 P2RX1 RBFOX1 TACSTD2 BBS12

1.23e-051741306eb8012823b08729b462d1e5212f4873bb6b4eb1e
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NTRK3 B4GALT5 P2RX1 RBFOX1 TACSTD2 BBS12

1.23e-05174130632fdeeebeeeca657eac6329caad4c28ca54e4d1c
ToppCell5'-Adult-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA ISYNA1 MYLK MTHFD2 NTRK2 NTRK3

1.27e-051751306294a70786260c9a2b1ba16c88819d786698609e7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA MTHFD2 NTRK2 NTRK3 RBM20 P2RX1

1.27e-051751306316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell5'-Adult-LymphNode-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA ISYNA1 MYLK MTHFD2 NTRK2 NTRK3

1.27e-051751306798f33bd340261c048b7b45c842b2ccd1ea1fb60
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA MTHFD2 NTRK2 NTRK3 RBM20 P2RX1

1.27e-051751306a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ISYNA1 NTRK2 ETV4 PFN2 UGT3A2 HSPA2

1.36e-0517713069e65b39fd797b6ce204b6480415810d1923acee5
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

VWF MYLK SHANK3 RCOR2 MALRD1 CTTN

1.45e-0517913064e0cf069bc47328eda753a4edc7e89b8915d52bb
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

CACNA1C FLNA MYLK NTRK2 NTRK3 HIPK2

1.45e-051791306a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

CACNA1C FLNA MYLK NTRK2 NTRK3 RBM20

1.49e-051801306d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MORN4 ETV4 ATP6AP1L TACSTD2 BICC1

1.64e-051081305fcc26843a8788f0fe3cec14dcae083830da80b8f
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MORN4 ETV4 ATP6AP1L TACSTD2 BICC1

1.64e-051081305c1c68e328fdf5216f23845b4de9a3b1bbe61b11c
ToppCellCOVID-19-Heart-CM_4|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1C MYOM3 RBM20 CADPS SH3PXD2A RBFOX1

1.64e-0518313062902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRAS1 BHMT AGXT2 CNNM1 TENM1 BICC1

1.64e-0518313066878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK4 NTRK2 HIPK2 IFI35 SHANK3 PRX

1.64e-051831306e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NTRK2 NTRK3 SLC12A5 P2RX1 ABCB11 MMP2

1.64e-051831306f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C FLNA MYLK NTRK3 RBFOX1 BICC1

1.80e-0518613066add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell(5)_Pericytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CACNA1C FLNA MYL1 MYLK NTRK2 P2RX1

1.80e-051861306acbca8cc048d87faf859b3e77bdb38d0a3dad71c
ToppCell(5)_Pericytes-(50)_Pericytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

CACNA1C FLNA MYL1 MYLK NTRK2 P2RX1

1.80e-05186130667b59defdd1ed3608229cc5e2a3b480d92312afa
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

CACNA1C CAMK1D MYOM3 RBM20 CADPS RBFOX1

1.91e-0518813066d249fe92d51a19da19ec14bb2262d394255d577
ToppCell5'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK8 IFI35 P2RX1 P2RX7 BTK HCLS1

1.91e-05188130672a1ee136d77c77e44793a512f60b5f7815a073a
ToppCell5'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK8 IFI35 P2RX1 P2RX7 BTK HCLS1

1.91e-051881306ecbba19eebba21b986caa99de78ea4245fde3600
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA ISYNA1 MYLK MTHFD2 NTRK3 CADPS

1.97e-051891306032f169e8ede653117919bf97c17f92043320b3c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA ISYNA1 MYLK MTHFD2 NTRK3 CADPS

1.97e-05189130607208d32afca6f93207a2ac35b647b31a9f71b7c
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 CDC42BPA NTRK2 PRX P2RX7 PRKCH

2.02e-051901306474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VWF NTRK2 COLEC10 SHANK3 PRX P2RX7

2.02e-051901306a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 NTRK2 COLEC10 SHANK3 PRX P2RX7

2.15e-051921306c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VWF NTRK2 SHANK3 PRX P2RX7 PRKCH

2.15e-05192130604f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellFetal_29-31_weeks-Immune-monocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CAMK1D KIAA0513 DOCK8 P2RX7 BTK HCLS1

2.15e-0519213065417f024fcc89eaeab33f4a2c6421d1cfabd681b
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VWF NTRK2 SHANK3 PRX P2RX7 PRKCH

2.15e-051921306c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellIPF-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

FLNA ISYNA1 MTHFD2 NTRK2 NTRK3 RBM20

2.15e-0519213069b06c7336624ef21f8e5393725b56038a8028e57
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA ISYNA1 MTHFD2 NTRK2 NTRK3 HSPA2

2.15e-0519213065995bae840c0b3f420288f557634d0ae9a12a6ae
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

DOCK4 VWF HIPK2 SHANK3 B4GALT5 PRKCH

2.21e-05193130601c2df9206f1527c578e808978e58196c35e72f5
ToppCellControl-Fibroblasts-Vascular_smooth_muscle|Control / group, cell type (main and fine annotations)

CACNA1C VWF MYLK NTRK2 SHANK3 PRX

2.21e-05193130660e44aac8be0430ad35e20eb98b1b700d76a0427
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_capillary_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

VWF NTRK2 SHANK3 SLC2A1 PRX PRKCH

2.28e-0519413063c31ac44e8cf4eca3ba7b8bfc05ad3e96a970956
ToppCell15-Airway-Mesenchymal-Pericyte|Airway / Age, Tissue, Lineage and Cell class

FLNA ISYNA1 MYLK MTHFD2 NTRK3 HSPA2

2.28e-0519413065c1218d239c88082496924653ed2a092dc44a906
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

CACNA1C FRAS1 MYOM3 RBM20 CADPS RBFOX1

2.28e-051941306c3535f7cc0076653c72db582047cff053c322397
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_capillary_(2)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

VWF NTRK2 SHANK3 SLC2A1 PRX PRKCH

2.41e-0519613062a2a93b89dcb98043cb1f8b422ac8c55e2edc37b
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FLNA ISYNA1 MYLK MTHFD2 NTRK2 NTRK3

2.41e-0519613061d94cecd378a829dd8014fc086d7fca48c953a91
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FLNA ISYNA1 MYLK MTHFD2 NTRK2 NTRK3

2.41e-051961306aacec48285bcb7ccf1b538187071885e3602cc49
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C FLNA MYLK NTRK2 NTRK3 BICC1

2.48e-051971306f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C FLNA MYLK NTRK3 RBM20 SACS

2.48e-051971306bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA ISYNA1 MTHFD2 NTRK2 NTRK3 HSPA2

2.48e-0519713061c91e3afcc5be195b827a1dff83aff5cc2492456
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C NTRK2 SLC12A5 CADPS RBFOX1 RBFOX2

2.55e-051981306c01091ef18e096d792ea2a7a715764a5b215355f
ToppCelldistal-3-mesenchymal-Vascular_Smooth_Muscle|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ISYNA1 MYLK NTRK3 PFN2 COCH HSPA2

2.55e-05198130637ce7b485ffb207e75afd1b576b486c6d59fc136
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA ISYNA1 MTHFD2 NTRK2 NTRK3 HSPA2

2.55e-0519813063222d064b6ecab0caa450a59fc1dc79e26fc6fd5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C NTRK2 SLC12A5 CADPS RBFOX1 RBFOX2

2.55e-0519813068ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCelldistal-mesenchymal-Vascular_Smooth_Muscle-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ISYNA1 MYLK NTRK3 PFN2 COCH HSPA2

2.55e-0519813065080767ff55326b7d94fca27d398237c4a15c1ed
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_2-VSMC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C FLNA ISYNA1 MYLK NTRK3 HSPA2

2.55e-051981306e967c601101361fc1c48dab0e5b76dc68813276e
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

CACNA1C FRAS1 SH3PXD2A MMP2 BICC1 RBFOX2

2.63e-0519913065b9d355795dd03a22f0961dfd143425c367a4654
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NTRK2 NTRK3 SLC2A1 BHMT SH3PXD2A ENTPD2

2.63e-051991306a13f4b8a039304e685464cc8879659824cad5a3e
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CACNA1C ISYNA1 MYLK NTRK3 RBM20 HSPA2

2.63e-051991306471738f2059e20407572d9c4cbd11812068333ea
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C FLNA MYLK MTHFD2 NTRK2 NTRK3

2.63e-0519913060a145172787f40d0fdaf21188d539ffaf7ece3e4
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ISYNA1 MTHFD2 NTRK2 NTRK3 P2RX3 HSPA2

2.63e-051991306f1723cfd6fbb8c8903a3b167872ec8523e3be250
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CACNA1C ISYNA1 MYLK NTRK3 RBM20 HSPA2

2.63e-051991306706b7de777ff86eb22e538ccd5c2987ceb6be308
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NTRK3 ETV4 BHMT ENTPD2 MMP2 BICC1

2.63e-05199130645c3b853900d8c3d5965117d904e3714100138bc
ToppCellMS-Multiple_Sclerosis-Others-HSPC|Multiple_Sclerosis / Disease, condition lineage and cell class

ISYNA1 CDC42BPA FAH P2RX1 MYL6B RBFOX2

2.63e-0519913067f4a22207a8b27af9a070d289e31ebd0e57af1a6
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ISYNA1 MYLK MTHFD2 NTRK2 NTRK3 HSPA2

2.63e-0519913069e32644b93fb1c4946dbe388fd5c357304d14e36
ToppCellParenchymal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CAMK1D DOCK8 P2RX1 P2RX7 BTK HCLS1

2.63e-0519913067ee2805fd9143eba11bf6832267b62189683608b
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CACNA1C ISYNA1 MYLK NTRK3 RBM20 HSPA2

2.63e-051991306690a4f84b205532c4c9e5c19d5ae430d0655f421
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FLNA ISYNA1 MYLK MTHFD2 NTRK3 PFN2

2.70e-0520013064fb6fd703aca9a992924245105ad99163146a415
ToppCellproximal-mesenchymal-Vascular_Smooth_Muscle-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ISYNA1 MYLK NTRK2 NTRK3 COCH HSPA2

2.70e-0520013065c0135d3cb6f7fa904e9760904dfe5f11c7e9102
ToppCellNS-moderate-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DDR1 CLIP1 CFAP298 GSPT1 CTTN TACSTD2

2.70e-05200130664462a18afca3c1a8548a857924b8166058bf958
ToppCellproximal-3-mesenchymal-Vascular_Smooth_Muscle|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ISYNA1 MYLK NTRK2 NTRK3 COCH HSPA2

2.70e-052001306870ab11343711f64fe6d6a858fc420fe17f1636a
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C FLNA MYLK NTRK3 RBM20 SACS

2.70e-052001306a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|367C / Donor, Lineage, Cell class and subclass (all cells)

MYLK PFN2 SH3PXD2A MMP2 BICC1 RBFOX2

2.70e-052001306082e718c1da3f4fdd33a001d15ad3ddb2be985c7
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ETV4 ATP6AP1L SLC2A1 SH3PXD2A ENTPD2 VPS53

2.70e-05200130624e13b6d9d2d8b29df1f02544ea9c50084d9e75c
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)|367C / Donor, Lineage, Cell class and subclass (all cells)

MYLK PFN2 SH3PXD2A MMP2 BICC1 RBFOX2

2.70e-052001306731e55070a7ff315091855bd88cda30e5a7e1a98
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NTRK2 ETV4 SLC2A1 SH3PXD2A ENTPD2 VPS53

2.70e-052001306f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCellmedial-mesenchymal-Airway_Smooth_Muscle|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CACNA1C ISYNA1 MYLK MTHFD2 NTRK3 HSPA2

2.70e-052001306c1d9748aaae489d26e24602a5dcbe7f5fa9a5548
ToppCellmedial-mesenchymal-Airway_Smooth_Muscle-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CACNA1C ISYNA1 MYLK MTHFD2 NTRK3 HSPA2

2.70e-0520013066a5047018b12be3bc4b55a64d42e52e96c624003
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RAP1GAP ETV4 BHMT ENTPD2 MMP2 BICC1

2.70e-05200130629054cf55e88e1ac81a562d8dd9af9b7c749321d
ToppCelldistal-mesenchymal-Airway_Smooth_Muscle|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CACNA1C ISYNA1 MYLK NTRK3 PFN2 HSPA2

2.70e-0520013061b5ac5b3ddd4df32e940531cc020998f8cd95c2c
ToppCellmedial-2-mesenchymal-Airway_Smooth_Muscle|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CACNA1C ISYNA1 MYLK MTHFD2 NTRK3 HSPA2

2.70e-05200130616b00eacbea4d75cf814803d3fc0b82c2b8c0a9c
ComputationalGenes in the cancer module 267.

P2RX1 P2RX3 P2RX4 P2RX7

4.65e-0615854MODULE_267
DrugBzATP

PTGES2 DUSP1 PRX TNFSF11 P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2

1.38e-0911713010CID000115205
DrugIp5I

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

4.31e-09121305CID004186342
DrugAC1O718G

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

4.31e-09121305CID000644357
DrugKN-62

CACNA1C MYL1 RARS1 MYLK TNFSF11 P2RX1 P2RX3 P2RX4 P2RX7 MYL6B PRKCH EIF2AK3

8.56e-0923013012CID000003838
DrugNf279

VWF P2RX1 P2RX3 P2RX4 P2RX7

1.61e-08151305CID000004467
DrugNSC36900

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2 CTTN

3.09e-08561307CID000235484
DrugAC1NSKPI

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2 EIF2AK3

3.51e-08571307CID005311482
DrugCibacron blue-agarose

ISYNA1 PFKM P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 KLKB1

1.18e-071011308CID000172468
DrugAC1N5WL5

PFKM P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2

2.65e-07761307CID004250634
Drug8-SPT

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2

8.82e-07571306CID000001908
DrugAC1O5RSQ

P2RX1 P2RX4 P2RX7 P2RX6 EIF2AK2

9.99e-07321305CID006439501
DrugAdo-5'-PP[S

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2

1.20e-06601306CID005310995
DrugATP,Gamma S

MYL1 MYLK P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 MYL6B ENTPD2

1.44e-061891309CID000002028
Drugarabinosyladenine

CACNA1C MYL1 VWF MYLK PFKM GRK1 P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 MYL6B ENTPD2 ABCB11 PRKCH MMP2 RBFOX2

1.66e-0676213017CID000000191
DrugAp6A

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

1.84e-06361305CID000123694
Drugfelodipine; Down 200; 10uM; MCF7; HT_HG-U133A_EA

LZTR1 MED14 ITPRID2 WNK1 SLC12A5 COCH HNRNPUL2 STEEP1 HSPA2

1.94e-061961309848_DN
DrugLopac-P-178

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2

2.31e-06671306CID005478935
Drug2-methylthioadenosine triphosphate

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 PRKCH

2.53e-06681306CID000001581
DrugBAPTA

CACNA1C MYL1 MYLK DUSP1 SLC2A1 P2RX1 P2RX7 SACS P2RX6 MYL6B PRKCH

2.64e-0632413011CID000104751
Drugcaged ATP

MYL1 MYLK WNK1 P2RX7 MYL6B ENTPD2

3.00e-06701306CID000123806
DrugAC1L1IO7

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2

3.54e-06721306CID000000194
Drug3'-AMP

PFKM P2RX1 P2RX4 P2RX7 P2RX6 CTTN

3.54e-06721306CID000041211
DrugKT5926

FLNA MYL1 MYLK MYL6B CTTN

4.03e-06421305CID000122126
DrugATP betaS

GRK1 P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2 PRKCH

4.30e-061621308CID005311341
DrugDPCPX

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2 PRKCH

4.95e-061171307CID000001329
DrugCalcium

CACNA1C DDR1 MYLK DUSP1 CDC42BPB SLC2A1 SLC12A5 TNFSF11 P2RX3 P2RX7 BTK ABCB11 EIF2AK3

5.14e-0649313013ctd:D002118
Drugsumatriptan

ADCY10 P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

6.56e-06801306CID000005358
Drugsodium

CACNA1C CD2AP PFN2 WNK1 SLC2A1 SLC12A5 METAP1 AGXT2 FAH P2RX3 P2RX4 P2RX7 SACS P2RX6 ENTPD2 ABCB11 PRKCH MMP2

7.17e-0694413018CID000000923
DrugBAPTA-AM

CACNA1C PTGES2 VWF MYLK DUSP1 MED14 TNFSF11 P2RX7 ABCB11 PRKCH

7.31e-0629313010CID000002293
DrugDMPX

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

7.90e-06481305CID000099562
DrugEvans blue dye

PTGES2 P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 MMP2

8.51e-061271307CID005356750
Drugeye gene

ADCY10 CACNA1C MYL1 RARS1 MYLK DUSP1 SLC2A1 TNFSF11 MYL6B PRKCH MMP2

9.08e-0636913011CID000004782
Drugreactive blue 2

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2

1.07e-05871306CID000656725
DrugNSC298883

MYL1 NTRK2 CD2AP P2RX7 SYNJ1 MYL6B

1.22e-05891306CID000326807
Drugpyridoxal

AGXT2 P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2

1.27e-051351307CID000001050
DrugAdenosine Triphosphate

PFKM SLC2A1 TNFSF11 P2RX1 P2RX3 P2RX4 P2RX7 ABCB11

1.55e-051931308ctd:D000255
DrugAC1L1DKE

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

1.55e-05551305CID000002388
DrugProtriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; HL60; HT_HG-U133A

FRAS1 CDC42BPA NTRK2 PRX RBFOX1 PRKCH PPIL2 HSPA2

1.80e-0519713083119_UP
DrugYO-PRO-1

P2RX1 P2RX4 P2RX7 P2RX6

1.87e-05281304CID006439500
DrugADP beta S

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2

1.88e-05961306CID005310996
DrugAC1L1KMJ

MYL1 VWF MYLK PFN2 CLIP1 SPTBN5 SACS MYL6B PRKCH MMP2 CTTN HCLS1

1.88e-0547613012CID000030956
DrugWB4101

P2RX3 P2RX4 P2RX7 P2RX6

2.16e-05291304CID000005685
Drugivermectin

P2RX1 P2RX3 P2RX4 CLCN6 P2RX7 ABCB11

2.51e-051011306CID006435110
Drugsuramin

WNT1 P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2 PRKCH

2.56e-052071308CID000005360
Drug8-phenyltheophylline

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6

2.80e-05621305CID000001922
DrugIp(5)I

P2RX1 P2RX3 P2RX4

2.90e-05111303CID006324651
Drugisoproterenol

ADCY10 CACNA1C PTGES2 MYL1 MYLK P2RX1 P2RX3 P2RX4 CLCN6 P2RX7 P2RX6 MYL6B PRKCH KLKB1

2.96e-0566913014CID000003779
Drugbenextramine

P2RX3 P2RX4 P2RX7 P2RX6

3.22e-05321304CID000002317
DrugAC1L1F6H

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2

3.30e-051061306CID000003104
Drugglutamate

SLC25A24 CACNA1C RARS1 MYLK NTRK2 NTRK3 PFKM SLC2A1 SLC12A5 AGXT2 P2RX1 P2RX3 P2RX4 CLCN6 P2RX7 PRKCH PSPC1

3.46e-0596213017CID000000611
DrugNF449

VWF HIPK2 P2RX1 P2RX7

3.65e-05331304CID005310945
DrugCH2OH

P2RX1 P2RX3 P2RX4 P2RX7

3.65e-05331304CID000137654
Drugphorbol acetate myristate

CACNA1C PTGES2 MYL1 CDC42BPA CAMK1D MYLK DUSP1 ETV4 SLC2A1 PRX GSPT1 TNFSF11 GSPT2 P2RX1 MYL6B PRKCH MMP2 CTTN HSPA2 EIF2AK2 EIF2AK3

4.34e-05139913021CID000004792
DrugSB-C

NTRK3 ETV4 SLC12A5 MST1R TENM1

4.71e-05691305CID005331010
DrugY-27632

CACNA1C MYL1 MYLK ETV4 PFN2 GRK1 P2RX7 MYL6B PRKCH MMP2 EIF2AK3

4.97e-0544413011CID000005711
Drugglycine

MTHFD2 MED14 GSPT1 AGXT2 ABCB11 PSPC1 KLKB1

5.38e-051691307CID000000750
Drugblebbistatin

MYL1 MYLK MYL6B ABCB11 MMP2 CTTN

5.48e-051161306CID003476986
Drugiso-H7

MYL1 MYLK MYL6B PRKCH

5.79e-05371304CID000001352
DrugAC1L1GTT

CACNA1C FLNA MYLK ETV4 P2RX1 P2RX7 PRKCH EIF2AK3

5.93e-052331308CID000003837
Drugpotassium

CACNA1C DDR1 ISYNA1 MYL1 MYLK WNK1 SLC12A5 METAP1 P2RX3 P2RX4 CLCN6 P2RX7 SACS MYL6B PRKCH KLKB1 RBFOX2

6.18e-05100813017CID000000813
Drugmyo-inositol

CACNA1C PTGES2 ISYNA1 MYL1 MYLK P2RX1 P2RX3 P2RX4 P2RX7 SYNJ1 P2RX6 HNRNPUL2 BTK PRKCH EIF2AK3

6.23e-0581113015CID000000892
Drug12-deoxyphorbol 13-isobutyrate

MYL1 MYLK MYL6B PRKCH

7.15e-05391304CID000107855
Drug2-aminoethyl diphenylborinate

CACNA1C DUSP1 GRK1 P2RX4 P2RX6 PRKCH

9.07e-051271306CID000001598
DrugNifuroxazide [965-52-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A

CDC42BPA CLIP1 P2RX4 HNRNPUL2 PPIL2 HSPA2 HERC4

1.05e-0418813074835_DN
Drugbromouridine

P2RX1 P2RX3 P2RX4 P2RX7

1.05e-04431304CID000091494
DrugAC1L1IZE

P2RX1 P2RX3 P2RX4 P2RX7 P2RX6 ENTPD2

1.08e-041311306CID000004799
DrugLY 294002; Down 200; 10uM; MCF7; HT_HG-U133A_EA

PTGES2 RAP1GAP PCGF2 USP24 SLC2A1 B4GALT5 HSPA2

1.09e-0418913071065_DN
Drug2-azido-ATP

PFKM WNK1 P2RX1

1.17e-04171303CID000123645
Drugcariporide

P2RX1 P2RX3 P2RX4 SACS P2RX6

1.35e-04861305CID000151172
DrugLY294002; Down 200; 10uM; MCF7; HG-U133A

EXOSC9 HIPK2 IFI35 SH3PXD2A PPIL2 HSPA2 BICC1

1.36e-041961307328_DN
Drugnifedipine

CACNA1C MYL1 VWF MYLK CD2AP SLC12A5 MYL6B PRKCH MMP2 EIF2AK3

1.39e-0441513010CID000004485
DrugProstaglandin E1; Up 200; 10uM; MCF7; HT_HG-U133A

PCGF2 RARS1 COCH P2RX4 SLC4A1AP ZFYVE26 HERC4

1.41e-0419713076576_UP
DrugSuxibuzone [27470-51-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A

ISYNA1 PCGF2 ITPRID2 COCH HNRNPUL2 PPIL2 RBFOX2

1.45e-0419813077163_DN
DrugPF-00539758-00 [351321-34-1]; Down 200; 10uM; MCF7; HT_HG-U133A

NTRK2 HIPK2 GSPT1 SPTBN5 CLCN6 RBFOX1 PPIL2

1.50e-0419913076416_DN
Drug5-(2-chlorophenyl)-2-furoic acid

FLNA NTRK2 SLC12A5 METAP1

1.50e-04471304CID000784625
Drugsodium 4-phenylbutyrate; Down 200; 1000uM; HL60; HG-U133A

RAP1GAP MYL1 VWF COLEC10 SLC2A1 CNNM1 TBL2

1.54e-042001307411_DN
Drugcyclophorine

CACNA1C MYLK USP24 TNFSF11 ABCB11 PRKCH PPIL2 MMP2 KLKB1 EIF2AK2

1.71e-0442613010CID000002909
Drug4,4'-diisothiocyanostilbene-2,2'-disulfonic acid

P2RX1 P2RX3 P2RX4 CLCN6 P2RX7 P2RX6 ENTPD2

1.85e-042061307CID000040600
Drugalpha,beta-methyleneadenosine 5'-triphosphate

P2RX1 P2RX3

1.93e-0441302ctd:C002630
DrugNf 107

P2RX1 P2RX3

1.93e-0441302CID000451438
DrugMRS2159

VWF MYLK P2RX1

1.93e-04201303CID006258690
DrugNf023

P2RX1 P2RX3 P2RX4

1.93e-04201303CID005311313
Druglavendustin B

PTGES2 NTRK2 NTRK3

2.24e-04211303CID000003895
DrugL 360

MYLK P2RX1 P2RX3

2.24e-04211303CID000005512
DrugU46619

CACNA1C PTGES2 MYL1 VWF MYLK P2RX1 MYL6B PRKCH

2.38e-042851308CID000005618
DrugPilocarpine

CACNA1C NTRK2 NTRK3 SLC12A5 P2RX7 PRKCH EIF2AK2 EIF2AK3

2.38e-042851308ctd:D010862
Diseaseazoospermia (implicated_via_orthology)

CDC42BPG ISYNA1 CDC42BPA CDC42BPB

4.53e-06271224DOID:14227 (implicated_via_orthology)
DiseaseChild Development Disorders, Specific

DOCK8 NTRK2 SHANK3 SLC2A1

6.10e-06291224C0085997
DiseaseChild Development Deviations

DOCK8 NTRK2 SHANK3 SLC2A1

6.10e-06291224C0085996
DiseaseDevelopmental Disabilities

DOCK8 NTRK2 SHANK3 SLC2A1

7.01e-06301224C0008073
DiseaseGrand Mal Status Epilepticus

NTRK2 NTRK3 SLC12A5 EIF2AK2 EIF2AK3

8.75e-06671225C0311335
DiseaseStatus Epilepticus, Subclinical

NTRK2 NTRK3 SLC12A5 EIF2AK2 EIF2AK3

8.75e-06671225C0751522
DiseaseSimple Partial Status Epilepticus

NTRK2 NTRK3 SLC12A5 EIF2AK2 EIF2AK3

8.75e-06671225C0751524
DiseaseNon-Convulsive Status Epilepticus

NTRK2 NTRK3 SLC12A5 EIF2AK2 EIF2AK3

8.75e-06671225C0751523
DiseasePetit mal status

NTRK2 NTRK3 SLC12A5 EIF2AK2 EIF2AK3

8.75e-06671225C0270823
DiseaseComplex Partial Status Epilepticus

NTRK2 NTRK3 SLC12A5 EIF2AK2 EIF2AK3

8.75e-06671225C0393734
DiseaseMalignant neoplasm of breast

FLNA RAP1GAP VWF PCDHGB6 MED14 ETV4 WNK1 CLIP1 ATP6AP1L SLC2A1 CCT5 BTK TENM1 SCP2 ZFYVE26 MMP2

9.39e-06107412216C0006142
DiseaseStatus Epilepticus

NTRK2 NTRK3 SLC12A5 EIF2AK2 EIF2AK3

9.42e-06681225C0038220
Diseasecerebral cavernous malformation (implicated_via_orthology)

CDC42BPG CDC42BPA CDC42BPB

1.11e-05111223DOID:0060669 (implicated_via_orthology)
Diseasehemangioma (is_marker_for)

SLC2A1 MMP2

1.70e-0521222DOID:255 (is_marker_for)
Diseaseage at assessment, pelvic organ prolapse

CAMK1D DUSP1 SACS RBFOX1

3.03e-05431224EFO_0004710, EFO_0008007
Diseasehypertension (biomarker_via_orthology)

VWF DUSP1 SLC2A1 FAH ENTPD2 MMP2 RBFOX2

4.60e-052271227DOID:10763 (biomarker_via_orthology)
Diseasebipolar disorder (is_marker_for)

RAP1GAP VWF NTRK2

6.37e-05191223DOID:3312 (is_marker_for)
DiseaseEpilepsy, Benign Psychomotor, Childhood

SLC12A5 P2RX4 P2RX7

1.15e-04231223C0393672
DiseaseEpilepsy, Lateral Temporal

SLC12A5 P2RX4 P2RX7

1.15e-04231223C0393682
DiseaseUncinate Epilepsy

SLC12A5 P2RX4 P2RX7

1.15e-04231223C0014558
DiseaseEpilepsy, Temporal Lobe

SLC12A5 P2RX4 P2RX7

1.15e-04231223C0014556
DiseaseIdiopathic generalized epilepsy

SLC2A1 SLC12A5

2.52e-0461222C0270850
DiseaseLarge cell carcinoma of lung

NTRK3 CDC42BPB BTK

3.13e-04321223C0345958
Diseasepulmonary venoocclusive disease (biomarker_via_orthology)

EIF2AK2 EIF2AK3

3.51e-0471222DOID:5453 (biomarker_via_orthology)
Diseaseinterleukin 16 measurement

P2RX4 P2RX7 KLKB1

4.46e-04361223EFO_0008173
Diseaseobsolete_red blood cell distribution width

DOCK8 DUSP1 CD2AP WNK1 ATP6AP1L SLC2A1 GTF2IRD2B CLCN6 CCT5 GTF2IRD2 SMG9 ABCB11 EIF2AK2 TBL2 RBFOX2

4.54e-04134712215EFO_0005192
Diseasefocal segmental glomerulosclerosis (is_marker_for)

RAP1GAP VWF

4.67e-0481222DOID:1312 (is_marker_for)
Diseaseprogrammed cell death 1 ligand 2 measurement

KLKB1 RIC1

4.67e-0481222EFO_0008268
DiseaseC-reactive protein measurement

SEMA6C DOCK4 RAP1GAP DUSP1 BHMT METAP1 MST1R TNFSF11 P2RX4 P2RX7 SLC4A1AP ABCB11 TBL2 FAM177A1

4.72e-04120612214EFO_0004458
DiseaseIntellectual Disability

PCGF2 RARS1 DOCK8 SHANK3 SLC2A1 SACS ARL13B VPS53

5.57e-044471228C3714756
Diseasesclerostin measurement

COLEC10 TNFSF11

5.99e-0491222EFO_0010606
DiseaseMood Disorders

CACNA1C NTRK2 NTRK3 SLC12A5 P2RX7

6.83e-041681225C0525045
DiseaseAutistic Disorder

DOCK4 CACNA1C LZTR1 NTRK2 SHANK3 RBFOX1

7.77e-042611226C0004352
Diseasealkaline phosphatase measurement

RAP1GAP ACADVL COLEC10 ATP6AP1L SLC12A5 METAP1 TNFSF11 P2RX7 SLC4A1AP ABCB11 TBL2 RIC1

1.04e-03101512212EFO_0004533
Diseaseevent free survival time, type 1 diabetes mellitus, autoantibody measurement

RBFOX1 PPIL2

1.09e-03121222EFO_0000482, EFO_0004866, MONDO_0005147
DiseaseCandidemia

SPTBN5 RBFOX2

1.09e-03121222EFO_1001282
Diseaseaminoadipic acid measurement

NTRK3 CADPS RBFOX1

1.17e-03501223EFO_0010459
DiseaseQRS amplitude, QRS complex

USP25 RBM20 CLCN6

1.17e-03501223EFO_0005054, EFO_0007742
DiseaseErythrocyte Mean Corpuscular Hemoglobin Test

ACADVL FAH

1.28e-03131222C0369183
DiseaseFinding of Mean Corpuscular Hemoglobin

ACADVL FAH

1.28e-03131222C1261502
Diseaseskin melanoma (is_marker_for)

DDR1 MMP2

1.28e-03131222DOID:8923 (is_marker_for)
Diseaseserum gamma-glutamyl transferase measurement

CDC42BPA RWDD2B COLEC10 CDC42BPB BHMT METAP1 P2RX4 P2RX7 ABCB11 TBL2 BICC1

1.47e-0391412211EFO_0004532
Diseaseatrial fibrillation (is_implicated_in)

VWF AGXT2

1.49e-03141222DOID:0060224 (is_implicated_in)
Diseaseintracranial aneurysm (is_marker_for)

VWF MMP2

1.49e-03141222DOID:10941 (is_marker_for)
DiseaseChronic Lymphocytic Leukemia

TNFSF11 P2RX7 BTK

1.55e-03551223C0023434
DiseaseAdenocarcinoma of lung (disorder)

NTRK2 NTRK3 WNK1 CCT5 EIF2AK2

1.69e-032061225C0152013
Diseaseacute graft vs. host disease, donor genotype effect measurement

SLC25A24 RBFOX1

1.72e-03151222EFO_0004599, EFO_0007892
DiseaseBreast Carcinoma

FLNA PCDHGB6 ETV4 ATP6AP1L SLC2A1 CCT5 BTK MMP2

1.82e-035381228C0678222
DiseasePontoneocerebellar hypoplasia

EXOSC9 VPS53

1.96e-03161222cv:C1261175
DiseaseInborn Errors of Metabolism

SLC2A1 AGXT2

2.21e-03171222C0025521
Diseasemajor depressive disorder (is_marker_for)

NTRK2 DUSP1

2.21e-03171222DOID:1470 (is_marker_for)
Diseaseresponse to cyclophosphamide

CAMK1D HIPK2

2.21e-03171222GO_1902518
DiseaseGlobal developmental delay

PCGF2 RARS1 SLC2A1 VPS53

2.30e-031331224C0557874
Diseasetype 1 diabetes mellitus (biomarker_via_orthology)

VWF DUSP1

2.77e-03191222DOID:9744 (biomarker_via_orthology)
Diseasesquamous cell carcinoma (is_marker_for)

DUSP1 MMP2

2.77e-03191222DOID:1749 (is_marker_for)
Diseaseserum homoarginine measurement

RAP1GAP AGXT2

3.07e-03201222EFO_0005421
DiseaseMalignant Glioma

MYLK NTRK2 NTRK3

3.09e-03701223C0555198
Diseasemixed gliomas

MYLK NTRK2 NTRK3

3.09e-03701223C0259783
Diseasemean platelet volume

VWF ZAN PCDHGB6 DOCK8 CD2AP CDC42BPB SHANK3 TXK FAH COCH P2RX1

3.42e-03102012211EFO_0004584
Diseaseleucine measurement

DRG1 MALRD1 KLKB1

3.47e-03731223EFO_0009770
Diseaseamblyopia

CAMK1D MALRD1

3.71e-03221222MONDO_0001020
DiseaseNasopharyngeal carcinoma

MST1R MMP2

3.71e-03221222C2931822
DiseaseCarcinoma of lung

NTRK2 NTRK3

4.05e-03231222C0684249
Diseaseidiopathic pulmonary fibrosis (is_marker_for)

DDR1 NTRK2

4.05e-03231222DOID:0050156 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
GFLKEAFELVRARGG

AGXT2

301

Q9BYV1
EIVIGDGGFVFALEK

BHMT

21

Q93088
EKFGRGVIAGLVDIG

EOLA1

76

Q8TE69
EKFGRGVIAGLVDIG

EOLA2

76

Q96DE9
RGGFGVVFEAKNKVD

EIF2AK3

601

Q9NZJ5
KQEGKEGGFIVRDSS

BTK

296

Q06187
RFKEKLGEGQFGEVH

DDR1

611

Q08345
DEKKGDGVRVGFFQL

ABCB11

36

O95342
KSGFFRVFIGVNDLE

COLEC10

201

Q9Y6Z7
RQGKFEVTIFDLGGG

ARL13B

61

Q3SXY8
IRGIGFGDIFKEGSV

CD2AP

211

Q9Y5K6
VLIFGGDILKFAGDA

ADCY10

86

Q96PN6
FFGGVSGLTVEQFRK

B4GALT5

271

O43286
KEEKVFLGGGAVEFL

BBS12

531

Q6ZW61
AEGKGRSGEDFFQKI

BICC1

66

Q9H694
KFEGDIKQEGVGAFR

ETV4

316

P43268
DGIAQIRGEIFFFKD

MMP2

476

P08253
RYGKDFGAIAEVIGN

RCOR2

346

Q8IZ40
SKQGFIGAGRRAKED

RBM20

371

Q5T481
DKKHTIFGRVVGGFD

PPIL2

391

Q13356
GIRFDIIVFGKAGKF

P2RX4

316

Q99571
EIIFNERGSKGFGFV

RBFOX2

151

O43251
DGFAVVFNDGKVGFI

RIC1

216

Q4ADV7
RVFVGGDDFKSGQTK

ISYNA1

296

Q9NPH2
FEILKVIGRGAFGEV

CDC42BPG

71

Q6DT37
VALFKTRDLDFGGNG

PCDHGB6

366

Q9Y5F9
ARTENVKGFFGGLET

KIAA0513

236

O60268
LEGGRAFFNAVKEGD

CADPS

586

Q9ULU8
IEERLGSGKFGQVFR

MYLK

1466

Q15746
AFKFDVVDGEGNRLI

FRAS1

2171

Q86XX4
VLEFLGRGTFGQVVK

HIPK2

201

Q9H2X6
FFVGEVDDGARKLVQ

METAP1

236

P53582
VGFKKSRDVFGLDFG

LZTR1

356

Q8N653
GFDVAKTGDARIGFV

DRG1

56

Q9Y295
ERGFENVELGVIGKK

FAM177A1

36

Q8N128
KRELGEGAFGKVFLA

NTRK3

541

Q16288
KGRTFDEIASGFRQG

SLC2A1

456

P11166
DERAFGGVIFQKKAA

ENTPD2

416

Q9Y5L3
KGEFETGFEKGGQTR

GSPT2

316

Q8IYD1
RKEGGKFGFAESIAN

EXOSC9

276

Q06265
KNVLIFDLGGGTFDV

HSPA2

196

P54652
EIFFGKTRNGGGDVD

IFI35

156

P80217
EEGKGIFDSRKNVLG

PFKM

646

P08237
DEVRFVFGGAFLKGD

CES5A

456

Q6NT32
IFVGEDAVDAGGVRK

HERC4

741

Q5GLZ8
FDGRGLKAENGQFEE

HNRNPUL2

336

Q1KMD3
GGGVHLFQKFVEERD

METTL18

331

O95568
DFVEGLRVFDKEGNG

MYL1

131

P05976
FEIIKVIGRGAFGEV

CDC42BPB

76

Q9Y5S2
LKGVLVRNGGSFEDD

ITPRID2

101

P28290
RKGEFETGFEKGGQT

GSPT1

186

P15170
DFQAFGVKGGRRINE

LRIT1

606

Q9P2V4
TVANGRVKFRVEGEF

MED14

216

O60244
LENGDGDKEKTGVRF

PCGF2

151

P35227
IVGKDREGFFTNGLT

PFN2

51

P35080
FGDEDFQLKFEGRVG

MALRD1

1431

Q5VYJ5
RFDILVFGTGGKFDI

P2RX7

316

Q99572
SGGAVFKKDDIGRRN

CFAP298

86

P57076
GVLFSVAGGLFVEKE

CLCN6

186

P51797
GKGAGFDVKALRAFR

CACNA1C

226

Q13936
GEFEKGGKSVARNVE

DOCK4

411

Q8N1I0
RVGFFGSKFGDLDEQ

DOCK8

1796

Q8NF50
IDFIDSIKNAGGRVF

DUSP1

241

P28562
DFKEIELIGSGGFGQ

EIF2AK2

266

P19525
FQAEEKGVRVLGGDR

CCER2

181

I3L3R5
ERVKQKDLGDGVYGF

FLNA

526

P21333
DFGGEELNVTFVKGV

KLKB1

301

P03952
GNGQTRKFLLDGDEV

FAH

376

P16930
GLFEKLRGGRAGFAD

FAM83H

471

Q6ZRV2
GQNRFEEVDLILKGG

HHIPL2

446

Q6UWX4
LDFRVLGKGGFGEVS

GRK1

191

Q15835
FTEFRVLGKGGFGEV

GRK7

191

Q8WTQ7
VNDLFSRKFGEAIGV

GTF2IRD2

336

Q86UP8
VNDLFSRKFGEAIGV

GTF2IRD2B

336

Q6EKJ0
KDVLFAIKEVGFRGG

COCH

226

O43405
FTEDDVRGIQNLGKG

SACS

2596

Q9NZJ4
GVVRFLGETDFAKGE

CLIP1

226

P30622
LRVGDVVKFAGQDFA

P2RX3

216

P56373
FRIGDLVAKAGGTFE

P2RX6

241

O15547
EGVVLRDKFGEAVNG

SLC12A5

481

Q9H2X9
RDKFGEAVNGNLVVG

SLC12A5

486

Q9H2X9
FGIRFDILVDGKAGK

P2RX1

311

P51575
VFHAGFGVVLGEDKK

RARS1

436

P54136
VEIIFNERGSKGFGF

RBFOX1

146

Q9NWB1
VTFIVDGAVVKFGQG

STEEP1

111

Q9H5V9
AGQVFRGFLEGKVTF

SYNJ1

766

O43426
AAKGFGGKYGVERDR

HCLS1

116

P14317
GDVDFEGVRQKAGYI

MTHFD2

291

P13995
FERDIKGESLFQGRG

TACSTD2

226

P09758
VKLQDFKGFRGGLDV

RAP1GAP

231

P47736
KERGGNQTSGIDFFI

SMG9

246

Q9H0W8
EKLGFAGLVQEISFG

CCT5

351

P48643
FQKGRAIDTGEVDIG

TENM1

391

Q9UKZ4
REGKFGAVEGAVAKY

PTGES2

266

Q9H7Z7
EEGEQFVKKIGGIFA

SCP2

446

P22307
DFEILKVIGRGAFGE

CDC42BPA

76

Q5VT25
VSGGELFDRIVEKGF

CAMK1D

101

Q8IU85
EGLELQKFGREVDGF

SPTBN5

1206

Q9NRC6
KEKITAFVVERGFGG

ACADVL

276

P49748
QGKVEVEVGKEGLRF

CNNM1

676

Q9NRU3
VEVGKEGLRFENGAF

CNNM1

681

Q9NRU3
KRELGEGAFGKVFLA

NTRK2

541

Q16620
GGEIELFDGEVNVKR

VWF

931

P04275
LGELKRFFEAAAGSG

MISP3

96

Q96FF7
YLEGFRVFDKEGNGK

MYL6B

146

P14649
KRDHEGFGFVLRGAK

SHANK3

576

Q9BYB0
DRGRATGKGFVEFAA

PSPC1

191

Q8WXF1
GFGGKFGVQTDRQDK

CTTN

231

Q14247
GISFRGGQKAEVIDK

SH3PXD2A

466

Q5TCZ1
FGLARGKEAEVQGDR

PRX

1066

Q9BXM0
FGLVRAKEGAEEGEK

PRX

1311

Q9BXM0
GRFLAVGVLEGKKFE

USP25

301

Q9UHP3
RGFEGKFKEQRSLDG

SEMA6C

341

Q9H3T2
GELIDRFVADFKAQG

VPS53

441

Q5VIR6
IFEEKVFSVNGARGN

RWDD2B

276

P57060
NVGGFFKLRSGEEIS

TNFSF11

276

O14788
LAFIKEIGSGQFGVV

TXK

271

P42681
VVDLVNKFGELGGFA

USP24

281

Q9UPU5
FGRLFGREFVDSGEK

WNT1

176

P04628
RELKQLIQGEFGDFF

TCHHL1

31

Q5QJ38
NDGRFLKFDIEIGRG

WNK1

216

Q9H4A3
FLEETLGGRGKFENL

UGT3A2

96

Q3SY77
IDFQIQGFAIKGGRF

ATP6AP1L

121

Q52LC2
GKNVEDGFGIAFRVL

ZFYVE26

2381

Q68DK2
EGQEVLFGVFVTGKD

MST1R

341

Q04912
EEGQKIGTFERFISG

SLC25A24

281

Q6NUK1
GKKGEFQEVVRAFEL

TBL2

261

Q9Y4P3
KGVFLGASGRFVELQ

ZAN

1246

Q9Y493
KFIAEGIIDQGGGFR

HECTD3

531

Q5T447
EGEFKNGRVDGFGLL

MORN4

86

Q8NDC4
GIDNFEFIRVLGKGS

PRKCH

351

P24723
KKALQGFFDREGEEL

SLC4A1AP

371

Q9BWU0
AVELEERGQKRVGFG

MYOM3

91

Q5VTT5