Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionL-alanine transmembrane transporter activity

SLC7A8 SLC36A3

2.02e-049482GO:0015180
GeneOntologyMolecularFunctionglycine transmembrane transporter activity

SLC7A8 SLC36A3

2.52e-0410482GO:0015187
Pubmed

MAP3K4 promotes fetal and placental growth by controlling the receptor tyrosine kinases IGF1R/IR and Akt signaling pathway.

MAP3K4 INSR

5.59e-06348235921893
Pubmed

ANO1 in intramuscular interstitial cells of Cajal plays a key role in the generation of slow waves and tone in the internal anal sphincter.

ANO1 CACNA1C

1.12e-05448228054347
Pubmed

Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations.

PLEKHG1 ULK4

3.90e-05748223972371
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLC7A8 SLCO2B1 INSR

4.19e-0410548330280653
Pubmed

The Maternal Microbiome Programs the m6A Epitranscriptome of the Mouse Fetal Brain and Intestine.

SULF1 INSR

5.48e-042548235874829
Pubmed

A Role for Sensory end Organ-Derived Signals in Regulating Muscle Spindle Proprioceptor Phenotype.

PLEKHG1 GPRC5B

9.01e-043248230926747
Pubmed

Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.

PLEKHG1 SMIM22 SULF1

1.32e-0315648322008794
CytobandEnsembl 112 genes in cytogenetic band chr11q13

ANO1 GDPD5 CARNS1 SLCO2B1

1.30e-03454484chr11q13
GeneFamilySolute carriers

SLC7A8 SLC36A3 SLCO2B1 SLC39A13 SLC23A3

5.16e-04395315752
ToppCellCOVID-19-Heart-EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANO1 CACNA1C PLEKHG1 TMTC1 RNF152 RBMS3

4.30e-08182486e67f3234165199085c793915ebb1f9bbd845e933
ToppCellwk_08-11-Mesenchymal-Mesothelial-Late_mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GDPD5 ZBTB7C CARNS1 SULF1 DOK7 SLC23A3

4.30e-08182486f8257c884393f168f605d371e0840cfca8d3657e
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 GDPD5 TMTC1 RNF152 SLCO2B1 GPRC5B

7.08e-081984869ab0db78394e730f6866b2db80047149024ad5f6
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHG1 GDPD5 TMTC1 RNF152 SLCO2B1 GPRC5B

7.08e-08198486e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

ANO1 CACNA1C TMTC1 RNF152 RBMS3

1.57e-06183485e3835db4795362b0442d5893baf2a78efcc20428
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

ANO1 CACNA1C TMTC1 RNF152 RBMS3

1.65e-06185485ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCellRV-07._Pericyte|World / Chamber and Cluster_Paper

ANO1 CACNA1C TMTC1 RNF152 RBMS3

1.74e-06187485dc274d6bbda619a2c914d84e2b4069cfef1739d1
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANO1 CACNA1C PLEKHG1 BRINP3 GPR137C

1.74e-06187485c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1C TMTC1 RBMS3 SULF1 INSR

1.74e-0618748576bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellCOVID-19-Epithelial-Ionocytes|COVID-19 / Condition, Lineage and Cell class

SMIM22 RHBDL2 RNF152 SULF1 GPRC5B

1.79e-06188485a581cb9528d0febbf3addbb4f6bc140f91a584e6
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1C PLEKHG1 TMTC1 RBMS3 INSR

2.14e-06195485a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellcellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EVC RHBDL2 RNF152 GPR137C

2.65e-051604849049707a4487f2337a17976ceb5fbd8815ab9e1d
ToppCellcellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EVC RHBDL2 RNF152 GPR137C

2.65e-05160484f2cfec54cf48a655f473b830be7d141c54b521ff
ToppCellcellseq2-Epithelial-Epithelial_Neuro-Secretory|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EVC RHBDL2 RNF152 GPR137C

2.65e-051604840eb50b3c494e1b65d40104b3b5411b57bb72b959
ToppCellCOVID-19-lung-Mesothelial|COVID-19 / Disease (COVID-19 only), tissue and cell type

GDPD5 ZBTB7C CARNS1 SULF1

2.92e-0516448483303e2ba52008391b8dc3fae8225ab5bcb20063
ToppCellEndothelial-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

PLEKHG1 TMTC1 RNF152 GPRC5B

2.99e-05165484b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANO1 CACNA1C RNF152 SDR9C7

2.99e-051654848a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANO1 EVC RNF152 RBMS3

3.44e-05171484a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

PLEKHG1 TMTC1 RNF152 GPRC5B

3.60e-05173484dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

PLEKHG1 TMTC1 RNF152 GPRC5B

3.60e-05173484a81992965137195d20fc498f750975303961a828
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANO1 CACNA1C RNF152 SDR9C7

3.60e-051734845416b092321c7d9b63f0418c60f2402a138355bf
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO1 SMIM22 RHBDL2 NLRP10

3.68e-05174484d927504d27b07bbc580bf57c60b383bd28624652
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANO1 CACNA1C RNF152 ZBTB7C

3.76e-051754841125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D175|Adult / Lineage, Cell type, age group and donor

GDPD5 TMTC1 SULF1 GPRC5B

3.76e-051754840a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GDPD5 RNF152 RBMS3 SULF1

3.85e-05176484322259a35f5c97d73ce7f75835dcdb5c954c91f8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANO1 TMTC1 ZBTB7C RBMS3

3.94e-051774844943d040eee0f9dceaddc7498171281d170e271f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANO1 TMTC1 ZBTB7C RBMS3

3.94e-051774843f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C ULK4 CDS1 EPM2A

4.02e-05178484fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellCOVID-19-kidney-REN+Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

ANO1 CACNA1C TMTC1 RBMS3

4.11e-05179484342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLEKHG1 TMTC1 SULF1 INSR

4.11e-051794841ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

ANO1 CACNA1C RNF152 ZBTB7C

4.11e-05179484a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EVC ZBTB7C SULF1 GPRC5B

4.20e-05180484c4068fe47408cfd899131a85fa4b7e5908926f94
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

ANO1 CACNA1C RNF152 RBMS3

4.29e-051814848dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANO1 CACNA1C RNF152 RBMS3

4.29e-0518148433cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

ANO1 CACNA1C RNF152 RBMS3

4.39e-051824842075efeae633550fb2eb026d0dfd741c8252482e
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

ANO1 TMTC1 RNF152 RBMS3

4.48e-05183484273db6a3b00a93ca852498471187b642b5368185
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1C PLEKHG1 TMTC1 ZBTB7C

4.48e-05183484ff95382cfed592190d0636d2b750328471f82e0d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 GDPD5 RBMS3 SULF1

4.48e-0518348404d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZBTB7C GPR137C SULF1 GPRC5B

4.48e-05183484351d575339038bd4a66f408da518c567444208e8
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO1 TTC34 RBMS3 SULF1

4.48e-05183484f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ZBTB7C CARNS1 SULF1 DOK7

4.67e-05185484492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 TMTC1 RHBDL2 SLCO2B1

4.67e-05185484808d5e880069aff8866cd2c733b9fe568a37701f
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO1 ZBTB7C CARNS1 RBMS3

4.67e-0518548438486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO1 ZBTB7C CARNS1 RBMS3

4.67e-051854843c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO1 CACNA1C ZBTB7C SULF1

4.77e-051864844780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 GDPD5 RBMS3 SULF1

4.87e-05187484d413fb4b1531b297af5012a392b88128510c2de8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANO1 TMTC1 ZBTB7C RBMS3

4.87e-05187484530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

CACNA1C RNF152 RBMS3 SULF1

4.87e-05187484464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANO1 TMTC1 ZBTB7C RBMS3

4.87e-05187484ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

ANO1 CACNA1C ULK4 RBMS3

4.87e-0518748492d468dde81125d51daf7abd4703741abe1ab91c
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

CACNA1C BRINP3 RBMS3 SULF1

4.98e-05188484706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZBTB7C CARNS1 SULF1 DOK7

4.98e-0518848400c5259bcb83218b7d44f4d585d9b68ef49763ab
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC1 ZBTB7C RBMS3 SULF1

4.98e-05188484ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

ANO1 CACNA1C BRINP3 GPR137C

5.08e-0518948444e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 TMTC1 RBMS3 SULF1

5.08e-0518948478cf414b98bcb19deb934409acddaad1cd51b67f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ANO1 CACNA1C TMTC1 BRINP3

5.08e-05189484da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 TMTC1 RBMS3 SULF1

5.18e-0519048426843ec1d19ac85a50990705353b802745d33e4d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 GDPD5 RBMS3 SULF1

5.18e-051904843f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

PLEKHG1 TMTC1 RNF152 GPRC5B

5.18e-0519048491bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 GDPD5 RBMS3 SULF1

5.18e-0519048439ab890104b4264c68a968f920f4ccd84f0bc681
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

ANO1 PLEKHG1 TMTC1 RNF152

5.18e-05190484a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

TMTC1 BRINP3 RBMS3 SULF1

5.18e-051904847dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO1 CACNA1C ZBTB7C SULF1

5.18e-0519048473d94fbae92029745989a8712eed8b99fd84c193
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC1 ZBTB7C RBMS3 SULF1

5.18e-05190484efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|kidney / Disease (COVID-19 only), tissue and cell type

PLEKHG1 TMTC1 RBMS3 SULF1

5.18e-051904841519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 GDPD5 RBMS3 SULF1

5.18e-05190484e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO1 CACNA1C SSPN ZBTB7C

5.29e-051914847853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANO1 TMTC1 ZBTB7C SULF1

5.29e-0519148404c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellCOVID-19-kidney-vSMC/Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

ANO1 CACNA1C TMTC1 RBMS3

5.29e-05191484fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

ANO1 CACNA1C RNF152 RBMS3

5.29e-0519148478c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell(5)_Epi_basal|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

SSPN RBMS3 GPRC5B INSR

5.29e-051914846bda3d5a8a391d41bb4d65872492e6c094bcc4d4
ToppCellControl-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

PLEKHG1 TMTC1 RNF152 GPRC5B

5.40e-05192484f95fb188aa642f3d0618242a770e7c4b70544adb
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1C PLEKHG1 TMTC1 INSR

5.40e-0519248427ff3621e177e7932dd44dd6baa81551ea75a874
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ANO1 TMTC1 RBMS3 SULF1

5.40e-05192484d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 TMTC1 RBMS3 SULF1

5.40e-0519248467d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLEKHG1 GDPD5 GPRC5B INSR

5.40e-051924845a0615fdc217554ccd611504b16e5d97628e207d
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C PLEKHG1 BRINP3 GPR137C

5.40e-0519248472881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

TMTC1 BRINP3 RBMS3 SULF1

5.40e-05192484d21f0f577156f17c899b08871046a26b88aea011
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 RNF152 SLCO2B1 GPRC5B

5.40e-051924840aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCellControl-Endothelial-Lymphatic|Control / Disease state, Lineage and Cell class

PLEKHG1 TMTC1 RNF152 GPRC5B

5.51e-0519348464d19be73e5432d491436a01da5de5c926b615a9
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANO1 CACNA1C ULK4 RBMS3

5.51e-05193484b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell(5)_Epithelial_cells-(5)_Epi_basal|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

SSPN RBMS3 GPRC5B INSR

5.62e-05194484b887b2ff19b76bd93c67f9a24762efae816efd45
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 TMTC1 SLCO2B1 GPRC5B

5.62e-0519448458f069efdefa0366033764446b9d6ffd4a17807e
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 TMTC1 RNF152 GPRC5B

5.62e-05194484f772a9f9ef8635aeaeb8b022dbb94e9672b36ead
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Tumor-Diffuse_large_B-cell_lymphoma-DLBCL-1|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

ANO1 SLCO2B1 SULF1 GPRC5B

5.62e-05194484eaeeb84576270cc3fc59002ba33bff9639bb0b02
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 TMTC1 SLCO2B1 GPRC5B

5.62e-05194484bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCellnucseq-Endothelial-Endothelial_Lymphatic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 TMTC1 RNF152 GPRC5B

5.62e-051944845d2b3ed5374e2ab10c1c7eb3a03139fc95036a48
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 TMTC1 RNF152 GPRC5B

5.62e-051944843b73f2d305a7566f7ab567e5f18c82cd3d80e32c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG1 TMTC1 SULF1 INSR

5.62e-05194484a429d22c8c9d0fd3bfa9f877a6364cecad68db30
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ANO1 BRINP3 ZBTB7C SULF1

5.62e-0519448469362e13158033de44f90f3773db6c0f27de8cb3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANO1 TMTC1 RBMS3 SULF1

5.73e-05195484edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellLPS_only-Endothelial-Endothelial-Activated_Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 TMTC1 RHBDL2 SLCO2B1

5.73e-0519548456efeb58df19f357d7d5ce87348d4f196a595421
ToppCellNS-moderate-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RHBDL2 RNF152 GPRC5B INSR

5.85e-0519648470384c1da9baed843f414cfd1403ddd586a2db07
ToppCellCOVID-19-kidney-VWF+PLVAP+VCAM1+EC|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1C PLEKHG1 TMTC1 RBMS3

5.85e-05196484ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANO1 TMTC1 RBMS3 SULF1

5.85e-05196484b8759e6231e0254797d6c30930407b79440c57bb
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TMTC1 SSPN RHBDL2 ZBTB7C

5.85e-05196484d5ed41fa111750e6b363c04cccc40a47dd774852
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANO1 TMTC1 RBMS3 SULF1

5.97e-0519748480e153790cef37b743e22a7370ff5b3a6abf147d
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMTC1 RNF152 RBMS3 SULF1

5.97e-0519748426475b9e4d6bfc0ae818dea13d139888ed7e92f1
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMTC1 RNF152 RBMS3 SULF1

5.97e-05197484155e63b33302a87393ace699b2f6d73abe9c5763
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Mucous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ANO1 SMIM22 EPM2A LRRC31

6.08e-051984842ae9564da9913510141994262f3739eb095e0a68
DiseaseDisproportionate short stature

EVC SULF1 SLC39A13

2.55e-0477473C0878659
Diseaselysophosphatidylethanolamine 18:0 measurement

TMTC1 RBMS3

2.57e-0415472EFO_0010367
Diseasebody weight

ANO1 CACNA1C ULK4 BRINP3 ZBTB7C RBMS3 GPRC5B INSR

7.75e-041261478EFO_0004338
Diseaseaortic root size

ANO1 CACNA1C

7.88e-0426472EFO_0005037
Diseasediastolic blood pressure, alcohol drinking

PLEKHG1 ULK4 INSR

8.89e-04118473EFO_0004329, EFO_0006336
Diseasediastolic blood pressure, unipolar depression

PLEKHG1 ULK4

1.05e-0330472EFO_0003761, EFO_0006336
Diseasepulse pressure measurement, diastolic blood pressure, systolic blood pressure, hypertension

PLEKHG1 ULK4

1.43e-0335472EFO_0000537, EFO_0005763, EFO_0006335, EFO_0006336

Protein segments in the cluster

PeptideGeneStartEntry
LVHMILGLSLQICLT

BRINP3

546

Q76B58
LALMVGLLTCQDIIN

CAGE1

621

Q8TC20
LMLLVLGIQVKCFHE

CDS1

111

Q92903
LVGVMCLVSQHLQAL

CARNS1

736

A5YM72
IQSQDRIMILHQLLC

RBMS3

351

Q6XE24
LALALIIIMGIVQIC

SLC7A8

196

Q9UHI5
MCNGIIILLIKIHPA

OR10AG1

31

Q8NH19
RVQMLPQAVCLLHAL

EPM2A

241

O95278
GQVILDQICSNIMLL

LIPM

261

Q5VYY2
MNLLELVDQLSHICL

NLRP10

81

Q86W26
LFLVVNLTCAMLVHG

GPR137C

176

Q8N3F9
IIALGHLVMSCGNIV

CAND1

196

Q86VP6
LVMLKHLQVLDLHQC

LRRC31

306

Q6UY01
HIMAQPLCIRALLNL

NEK8

251

Q86SG6
VLLQVLHVLLGMCQA

PI4KA

156

P42356
LHVLLGMCQALEIQD

PI4KA

161

P42356
VLALCHIAVGQQMNL

GDPD5

106

Q8WTR4
CIQLSIIMLGKQLIQ

ANO1

661

Q5XXA6
ENCSVIEGHLQILLM

INSR

51

P06213
QLVGLALCLMLVQVI

GPRC5B

161

Q9NZH0
FVLILLNTICLAMQH

CACNA1C

1246

Q13936
NVNLVGLIEVTLHML

SDR9C7

131

Q8NEX9
IPLLINAIDHCMNRI

CCNDBP1

336

O95273
LQQHMECAIGQALLV

EVC

736

P57679
INILVCTPGRLLQHM

DDX10

191

Q13206
HTLAIVCLSQAIMLG

DOK7

76

Q18PE1
QQLLLLCAGIVVMVL

SLC39A13

351

Q96H72
GNAIIMTIICIDRHL

OR10J6P

41

Q8NGY7
MNIISRQLCHLLVAG

OR4B1

131

Q8NGF8
LSLQALMNECIGHVI

MAP3K4

1116

Q9Y6R4
QLQVHMVLQLCPVLG

RPUSD3

246

Q6P087
AGVQHILGNLCMQLV

RHBDL2

131

Q9NX52
ACVLVFLLGIVLHNM

RNF152

176

Q8N8N0
NAILLVAMLLCTGLV

RNF215

256

Q9Y6U7
MGTVLLLLLLVVAHC

SMIM22

41

K7EJ46
LIQMILNLVCGLVCL

SSPN

196

Q14714
GLSCLLALQHVLVMA

SLC23A3

46

Q6PIS1
LALQHVLVMASLLCV

SLC23A3

51

Q6PIS1
GLALLVILLMVVCSQ

SLC23A3

221

Q6PIS1
AIGVLTVHCMVILLN

SLC36A3

81

Q495N2
AVNIILHCLVTLVLM

TMTC1

116

Q8IUR5
FVLCHSLLQLAQLMI

SLCO2B1

51

O94956
HILNAARMLEIQCIV

ZBTB7C

106

A1YPR0
KAHILCGNLMLVEVI

PLEKHG1

361

Q9ULL1
IGCLVIHALLNLMSS

YIPF7

181

Q8N8F6
ILNQLHVQLMELRSC

SULF1

821

Q8IWU6
VACGVHQLATLLMEL

TTC34

31

A8MYJ7
ALICLRIGQEMVQQH

WDR81

1406

Q562E7
AMLSCGIHLQRLIQE

ULK4

716

Q96C45
LCDLAAILGMHNLIT

TMOD3

131

Q9NYL9
VLLLGHVAQVLMLDN

NAGA

6

P17050