Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	peptidase regulator activity	COL7A1 SFRP2 CRIM1 SPINT1 SSPOP FBLN1 UMODL1 WFIKKN2 SLPI AHSG	1.46e-06	257	109	10	GO:0061134
GeneOntologyMolecularFunction	integrin binding	SELP SFRP2 ADAM18 ADAM9 SVEP1 FBLN1 FBN1 CCN2	5.31e-06	175	109	8	GO:0005178
GeneOntologyMolecularFunction	peptidase inhibitor activity	COL7A1 CRIM1 SPINT1 SSPOP UMODL1 WFIKKN2 SLPI AHSG	8.64e-06	187	109	8	GO:0030414
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL2A1 THSD4 COL7A1 SSPOP FBLN1 FBN1 COL14A1 LTBP2	8.98e-06	188	109	8	GO:0005201
GeneOntologyMolecularFunction	growth factor binding	COL2A1 TGFBR3 IGFBP4 WFIKKN2 CCN2 LTBP2 LTBP3	2.37e-05	156	109	7	GO:0019838
GeneOntologyMolecularFunction	metalloendopeptidase activity	ADAMTS19 ADAM18 ADAM9 TMPRSS6 ADAMTS18 ADAMTSL2	5.08e-05	120	109	6	GO:0004222
GeneOntologyMolecularFunction	calcium ion binding	SELP CACNA1E VLDLR PCDHB2 DLL1 LRP1B SVEP1 FBLN1 FBN1 UMODL1 LRP1 MACF1 LTBP2 LTBP3	5.73e-05	749	109	14	GO:0005509
GeneOntologyMolecularFunction	sulfur compound binding	SELP SFRP1 FTSJ1 TGFBR3 FBN1 LRP1 CCN2 LTBP2 FST	7.01e-05	323	109	9	GO:1901681
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	VLDLR LRP1B LRP1	8.41e-05	16	109	3	GO:0005041
GeneOntologyMolecularFunction	histone H3K27 trimethyltransferase activity	EZH1 NSD3	8.83e-05	3	109	2	GO:0140951
GeneOntologyMolecularFunction	endopeptidase regulator activity	COL7A1 SFRP2 CRIM1 SPINT1 WFIKKN2 SLPI AHSG	1.18e-04	201	109	7	GO:0061135
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	VLDLR LRP1B LRP1	1.96e-04	21	109	3	GO:0030228
GeneOntologyMolecularFunction	serine-type endopeptidase inhibitor activity	COL7A1 CRIM1 SPINT1 WFIKKN2 SLPI	2.77e-04	105	109	5	GO:0004867
GeneOntologyMolecularFunction	transforming growth factor beta binding	TGFBR3 WFIKKN2 LTBP3	3.75e-04	26	109	3	GO:0050431
GeneOntologyMolecularFunction	cell adhesion molecule binding	DAB2IP SELP SFRP2 ADAM18 ADAM9 SVEP1 FBLN1 FBN1 P2RX4 MACF1 CCN2	4.34e-04	599	109	11	GO:0050839
GeneOntologyMolecularFunction	microfibril binding	LTBP2 ADAMTSL2	4.37e-04	6	109	2	GO:0050436
GeneOntologyMolecularFunction	histone H3K27 methyltransferase activity	EZH1 NSD3	4.37e-04	6	109	2	GO:0046976
GeneOntologyMolecularFunction	endopeptidase inhibitor activity	COL7A1 CRIM1 SPINT1 WFIKKN2 SLPI AHSG	4.64e-04	180	109	6	GO:0004866
GeneOntologyMolecularFunction	heparin binding	SELP SFRP1 TGFBR3 FBN1 CCN2 LTBP2	6.52e-04	192	109	6	GO:0008201
GeneOntologyMolecularFunction	metallopeptidase activity	ADAMTS19 ADAM18 ADAM9 TMPRSS6 ADAMTS18 ADAMTSL2	8.06e-04	200	109	6	GO:0008237
GeneOntologyMolecularFunction	fibronectin binding	SFRP2 FBLN1 CCN2	1.16e-03	38	109	3	GO:0001968
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	SETD1A EZH1 NSD3	1.78e-03	44	109	3	GO:0140938
GeneOntologyMolecularFunction	activin binding	TGFBR3 FST	1.88e-03	12	109	2	GO:0048185
GeneOntologyMolecularFunction	clathrin heavy chain binding	LRP1 LMBRD1	1.88e-03	12	109	2	GO:0032050
GeneOntologyMolecularFunction	extracellular matrix structural constituent conferring tensile strength	COL2A1 COL7A1 COL14A1	2.02e-03	46	109	3	GO:0030020
GeneOntologyMolecularFunction	endopeptidase activity	ADAMTS19 SFRP1 ADAM18 USP9X ADAM9 TMPRSS6 ADAMTS18 ADAMTSL2	2.48e-03	430	109	8	GO:0004175
GeneOntologyMolecularFunction	enzyme inhibitor activity	COL7A1 CRIM1 SPINT1 SSPOP UMODL1 WFIKKN2 SLPI AHSG	2.66e-03	435	109	8	GO:0004857
GeneOntologyMolecularFunction	proteoglycan binding	COL2A1 LRP1 FST	2.72e-03	51	109	3	GO:0043394
GeneOntologyMolecularFunction	glycosaminoglycan binding	SELP SFRP1 TGFBR3 FBN1 CCN2 LTBP2	3.54e-03	268	109	6	GO:0005539
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	DAB2IP SFRP1 SFRP2 CHRDL2 CRIM1 AXL USP9X ADAM9 TMPRSS6 DLL1 SVEP1 TGFBR3 AKAP4 FBN1 IGFBP4 NFATC4 WFIKKN2 FSHR ARID5B LRP1 SIK2 AHSG CCN2 LTBP2 LTBP3 FST ADAMTSL2	4.47e-11	1186	107	27	GO:0007167
GeneOntologyBiologicalProcess	extracellular matrix organization	COL2A1 THSD4 ADAMTS19 COL7A1 SFRP2 SPINT1 TMPRSS6 TGFBR3 FBLN1 FSHR LRP1 ADAMTS18 COL14A1 CCN2 ADAMTSL2	1.06e-09	377	107	15	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	COL2A1 THSD4 ADAMTS19 COL7A1 SFRP2 SPINT1 TMPRSS6 TGFBR3 FBLN1 FSHR LRP1 ADAMTS18 COL14A1 CCN2 ADAMTSL2	1.09e-09	378	107	15	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	COL2A1 THSD4 ADAMTS19 COL7A1 SFRP2 SPINT1 TMPRSS6 TGFBR3 FBLN1 FSHR LRP1 ADAMTS18 COL14A1 CCN2 ADAMTSL2	1.13e-09	379	107	15	GO:0045229
GeneOntologyBiologicalProcess	cell surface receptor protein serine/threonine kinase signaling pathway	SFRP1 SFRP2 CHRDL2 CRIM1 USP9X ADAM9 TMPRSS6 TGFBR3 AKAP4 FBN1 WFIKKN2 LRP1 LTBP2 LTBP3 FST ADAMTSL2	3.80e-09	482	107	16	GO:0007178
GeneOntologyBiologicalProcess	transforming growth factor beta receptor superfamily signaling pathway	SFRP1 SFRP2 CHRDL2 CRIM1 USP9X ADAM9 TMPRSS6 TGFBR3 FBN1 WFIKKN2 LRP1 LTBP2 LTBP3 FST ADAMTSL2	9.94e-09	445	107	15	GO:0141091
GeneOntologyBiologicalProcess	cellular response to growth factor stimulus	COL2A1 DAB2IP SFRP1 SFRP2 CHRDL2 CRIM1 SPINT1 USP9X ADAM9 TMPRSS6 DLL1 TGFBR3 FBN1 WFIKKN2 LRP1 CCN2 LTBP2 LTBP3 FST ADAMTSL2	1.29e-08	850	107	20	GO:0071363
GeneOntologyBiologicalProcess	response to BMP	COL2A1 SFRP1 SFRP2 CHRDL2 CRIM1 SPINT1 USP9X TMPRSS6 TGFBR3 FBN1 FST	1.58e-08	215	107	11	GO:0071772
GeneOntologyBiologicalProcess	cellular response to BMP stimulus	COL2A1 SFRP1 SFRP2 CHRDL2 CRIM1 SPINT1 USP9X TMPRSS6 TGFBR3 FBN1 FST	1.58e-08	215	107	11	GO:0071773
GeneOntologyBiologicalProcess	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	SFRP1 SFRP2 CHRDL2 CRIM1 TMPRSS6 TGFBR3 FBN1 WFIKKN2 LRP1 FST ADAMTSL2	1.82e-08	218	107	11	GO:0090101
GeneOntologyBiologicalProcess	response to growth factor	COL2A1 DAB2IP SFRP1 SFRP2 CHRDL2 CRIM1 SPINT1 USP9X ADAM9 TMPRSS6 DLL1 TGFBR3 FBN1 WFIKKN2 LRP1 CCN2 LTBP2 LTBP3 FST ADAMTSL2	2.43e-08	883	107	20	GO:0070848
GeneOntologyBiologicalProcess	regulation of cellular response to growth factor stimulus	DAB2IP SFRP1 SFRP2 CHRDL2 CRIM1 TMPRSS6 DLL1 TGFBR3 FBN1 WFIKKN2 LRP1 FST ADAMTSL2	2.21e-07	412	107	13	GO:0090287
GeneOntologyBiologicalProcess	regulation of BMP signaling pathway	SFRP1 SFRP2 CHRDL2 CRIM1 TMPRSS6 TGFBR3 FBN1 FST	4.11e-07	131	107	8	GO:0030510
GeneOntologyBiologicalProcess	BMP signaling pathway	SFRP1 SFRP2 CHRDL2 CRIM1 USP9X TMPRSS6 TGFBR3 FBN1 FST	8.82e-07	197	107	9	GO:0030509
GeneOntologyBiologicalProcess	female sex differentiation	SFRP1 AXL ZFPM2 ZFX UMODL1 FSHR ARID5B FST	1.62e-06	157	107	8	GO:0046660
GeneOntologyBiologicalProcess	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	SFRP1 SFRP2 CHRDL2 CRIM1 TMPRSS6 TGFBR3 FBN1 WFIKKN2 LRP1 FST ADAMTSL2	1.92e-06	347	107	11	GO:0090092
GeneOntologyBiologicalProcess	sex differentiation	SFRP1 SFRP2 ADAM18 AXL ZFPM2 ZFX UMODL1 FSHR ARID5B AHSG FST	2.20e-06	352	107	11	GO:0007548
GeneOntologyBiologicalProcess	gonad development	SFRP1 SFRP2 ADAM18 ZFPM2 ZFX UMODL1 FSHR ARID5B AHSG FST	2.91e-06	292	107	10	GO:0008406
GeneOntologyBiologicalProcess	development of primary sexual characteristics	SFRP1 SFRP2 ADAM18 ZFPM2 ZFX UMODL1 FSHR ARID5B AHSG FST	3.38e-06	297	107	10	GO:0045137
GeneOntologyBiologicalProcess	negative regulation of BMP signaling pathway	SFRP1 SFRP2 CHRDL2 CRIM1 TMPRSS6 FBN1	3.72e-06	80	107	6	GO:0030514
GeneOntologyBiologicalProcess	developmental growth	DIP2B BNC2 ARHGAP32 SFRP1 SFRP2 USP9X DLL1 ZFPM2 ZFX TGFBR3 FMN1 FSHR ARID5B LRP1 MACF1 COL14A1 KDF1	4.39e-06	911	107	17	GO:0048589
GeneOntologyBiologicalProcess	growth	DAB2IP DIP2B BNC2 ARHGAP32 SFRP1 SFRP2 USP9X DLL1 ZFPM2 ZFX TGFBR3 IGFBP4 FMN1 FSHR ARID5B LRP1 AHSG MACF1 COL14A1 KDF1	4.87e-06	1235	107	20	GO:0040007
GeneOntologyBiologicalProcess	reproductive structure development	SFRP1 SFRP2 ADAM18 AXL ZFPM2 ZFX UMODL1 FSHR ARID5B AHSG FST	4.94e-06	383	107	11	GO:0048608
GeneOntologyBiologicalProcess	reproductive system development	SFRP1 SFRP2 ADAM18 AXL ZFPM2 ZFX UMODL1 FSHR ARID5B AHSG FST	5.58e-06	388	107	11	GO:0061458
GeneOntologyBiologicalProcess	female gonad development	SFRP1 ZFPM2 ZFX UMODL1 FSHR ARID5B FST	7.70e-06	138	107	7	GO:0008585
GeneOntologyBiologicalProcess	development of primary female sexual characteristics	SFRP1 ZFPM2 ZFX UMODL1 FSHR ARID5B FST	9.28e-06	142	107	7	GO:0046545
GeneOntologyBiologicalProcess	negative regulation of cellular response to growth factor stimulus	DAB2IP SFRP1 SFRP2 CHRDL2 CRIM1 TMPRSS6 FBN1	1.33e-05	150	107	7	GO:0090288
GeneOntologyBiologicalProcess	transforming growth factor beta receptor signaling pathway	USP9X ADAM9 TGFBR3 FBN1 WFIKKN2 LRP1 LTBP2 LTBP3 ADAMTSL2	1.38e-05	276	107	9	GO:0007179
GeneOntologyBiologicalProcess	skeletal system development	COL2A1 BNC2 SFRP1 SFRP2 CHRDL2 FBN1 FMN1 WFIKKN2 ARID5B AHSG CCN2 LTBP3 FST	1.80e-05	615	107	13	GO:0001501
GeneOntologyBiologicalProcess	negative regulation of multicellular organismal process	DAB2IP DIP2B SFRP1 SFRP2 AXL ADGRB2 CD83 IL17D DLL1 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 P2RX4 ZNF608 NFATC4 FSHR AHSG ADAMTS18 LTBP3	2.23e-05	1488	107	21	GO:0051241
GeneOntologyBiologicalProcess	male gonad development	SFRP1 SFRP2 ADAM18 ZFPM2 FSHR ARID5B AHSG	3.09e-05	171	107	7	GO:0008584
GeneOntologyBiologicalProcess	development of primary male sexual characteristics	SFRP1 SFRP2 ADAM18 ZFPM2 FSHR ARID5B AHSG	3.21e-05	172	107	7	GO:0046546
GeneOntologyBiologicalProcess	negative regulation of cell differentiation	DAB2IP DIP2B SFRP1 SFRP2 CRIM1 IL17D DLL1 ZFPM2 TGFBR3 FBN1 ZNF608 NFATC4 LTBP3 FST USH2A	4.54e-05	875	107	15	GO:0045596
GeneOntologyBiologicalProcess	regulation of cell development	DIP2B SETD1A ARHGAP32 SFRP1 SPINT1 AXL KAT6A CD83 IL17D DLL1 TF FBN1 ZNF608 NFATC4 FSHR LRP1 MACF1	4.70e-05	1095	107	17	GO:0060284
GeneOntologyBiologicalProcess	regulation of tissue remodeling	SFRP1 TF FSHR LRP1 AHSG LTBP3	5.50e-05	128	107	6	GO:0034103
GeneOntologyBiologicalProcess	regulation of bone remodeling	SFRP1 TF FSHR AHSG LTBP3	6.04e-05	80	107	5	GO:0046850
GeneOntologyBiologicalProcess	anatomical structure homeostasis	COL2A1 TF P2RX4 FSHR AHSG COL14A1 CCN2 LTBP3 USH2A	6.13e-05	334	107	9	GO:0060249
GeneOntologyBiologicalProcess	tissue homeostasis	COL2A1 TF P2RX4 FSHR AHSG COL14A1 CCN2 LTBP3 USH2A	6.13e-05	334	107	9	GO:0001894
GeneOntologyBiologicalProcess	cellular response to transforming growth factor beta stimulus	USP9X ADAM9 TGFBR3 FBN1 WFIKKN2 LRP1 LTBP2 LTBP3 ADAMTSL2	6.41e-05	336	107	9	GO:0071560
GeneOntologyBiologicalProcess	tissue remodeling	SFRP1 AXL TF TGFBR3 FSHR LRP1 AHSG LTBP3	6.71e-05	262	107	8	GO:0048771
GeneOntologyBiologicalProcess	response to transforming growth factor beta	USP9X ADAM9 TGFBR3 FBN1 WFIKKN2 LRP1 LTBP2 LTBP3 ADAMTSL2	7.51e-05	343	107	9	GO:0071559
GeneOntologyBiologicalProcess	regulation of midbrain dopaminergic neuron differentiation	SFRP1 SFRP2	7.97e-05	3	107	2	GO:1904956
GeneOntologyBiologicalProcess	cerebellar cortex structural organization	USP9X DLL1	7.97e-05	3	107	2	GO:0021698
GeneOntologyBiologicalProcess	male sex differentiation	SFRP1 SFRP2 ADAM18 ZFPM2 FSHR ARID5B AHSG	8.09e-05	199	107	7	GO:0046661
GeneOntologyBiologicalProcess	multicellular organismal-level homeostasis	COL2A1 SETD1A AXL TMPRSS6 EZH1 DLL1 TF ZFX TGFBR3 P2RX4 FSHR AHSG COL14A1 CCN2 LTBP3 USH2A	9.26e-05	1043	107	16	GO:0048871
GeneOntologyBiologicalProcess	negative regulation of peptidase activity	COL7A1 SFRP2 SPINT1 WFIKKN2 SLPI LRP1 AHSG	1.13e-04	210	107	7	GO:0010466
GeneOntologyBiologicalProcess	cell surface receptor protein tyrosine kinase signaling pathway	DAB2IP CRIM1 AXL DLL1 SVEP1 IGFBP4 NFATC4 FSHR ARID5B LRP1 SIK2 AHSG CCN2	1.31e-04	747	107	13	GO:0007169
GeneOntologyBiologicalProcess	negative regulation of Wnt signaling pathway, planar cell polarity pathway	SFRP1 SFRP2	1.59e-04	4	107	2	GO:0141113
GeneOntologyBiologicalProcess	Wnt signaling pathway involved in somitogenesis	SFRP1 SFRP2	1.59e-04	4	107	2	GO:0090244
GeneOntologyBiologicalProcess	negative regulation of hydrolase activity	DAB2IP COL7A1 SFRP2 SPINT1 WFIKKN2 SLPI LRP1 AHSG	1.63e-04	298	107	8	GO:0051346
GeneOntologyBiologicalProcess	developmental growth involved in morphogenesis	DIP2B ARHGAP32 SFRP1 SFRP2 USP9X FMN1 LRP1 MACF1	1.67e-04	299	107	8	GO:0060560
GeneOntologyBiologicalProcess	negative regulation of developmental process	DAB2IP DIP2B SFRP1 SFRP2 CRIM1 ADGRB2 IL17D DLL1 ZFPM2 TGFBR3 FBN1 ZNF608 NFATC4 AHSG LTBP3 FST USH2A	1.75e-04	1220	107	17	GO:0051093
GeneOntologyBiologicalProcess	regulation of growth	DAB2IP DIP2B ARHGAP32 SFRP1 SFRP2 DLL1 ZFPM2 TGFBR3 IGFBP4 LRP1 AHSG MACF1 COL14A1	1.93e-04	777	107	13	GO:0040008
GeneOntologyBiologicalProcess	negative regulation of epithelial to mesenchymal transition	DAB2IP SFRP1 SFRP2 TGFBR3	2.04e-04	56	107	4	GO:0010719
GeneOntologyBiologicalProcess	roof of mouth development	COL2A1 BNC2 TGFBR3 WFIKKN2 ARID5B	2.09e-04	104	107	5	GO:0060021
GeneOntologyBiologicalProcess	cell-substrate adhesion	SFRP1 AXL ADAM9 SVEP1 FBLN1 FMN1 LRP1 MACF1 CCN2	2.86e-04	410	107	9	GO:0031589
GeneOntologyBiologicalProcess	negative regulation of proteolysis	COL7A1 SFRP2 SPINT1 USP9X WFIKKN2 SLPI LRP1 AHSG	3.00e-04	326	107	8	GO:0045861
GeneOntologyBiologicalProcess	tube development	COL2A1 DAB2IP SFRP1 SFRP2 SPINT1 KAT6A ESRP1 ADGRB2 DLL1 ZFPM2 TGFBR3 FBN1 NFATC4 FMN1 LRP1 CCN2 LTBP3 ADAMTSL2	3.04e-04	1402	107	18	GO:0035295
GeneOntologyBiologicalProcess	regulation of cell growth	DAB2IP DIP2B ARHGAP32 SFRP1 SFRP2 IGFBP4 LRP1 AHSG MACF1 COL14A1	3.70e-04	519	107	10	GO:0001558
GeneOntologyBiologicalProcess	positive regulation of growth	ARHGAP32 SFRP1 SFRP2 DLL1 ZFPM2 TGFBR3 LRP1 MACF1	3.90e-04	339	107	8	GO:0045927
GeneOntologyBiologicalProcess	inner ear receptor cell fate commitment	ESRP1 DLL1	3.95e-04	6	107	2	GO:0060120
GeneOntologyBiologicalProcess	auditory receptor cell fate commitment	ESRP1 DLL1	3.95e-04	6	107	2	GO:0009912
GeneOntologyBiologicalProcess	cell growth	DAB2IP DIP2B ARHGAP32 SFRP1 SFRP2 USP9X IGFBP4 LRP1 AHSG MACF1 COL14A1	4.03e-04	625	107	11	GO:0016049
GeneOntologyBiologicalProcess	positive regulation of bone resorption	TF AHSG LTBP3	4.05e-04	28	107	3	GO:0045780
GeneOntologyBiologicalProcess	regulation of focal adhesion assembly	SFRP1 FMN1 LRP1 MACF1	4.82e-04	70	107	4	GO:0051893
GeneOntologyBiologicalProcess	regulation of cell-substrate junction assembly	SFRP1 FMN1 LRP1 MACF1	4.82e-04	70	107	4	GO:0090109
GeneOntologyBiologicalProcess	regulation of bone resorption	TF FSHR AHSG LTBP3	4.82e-04	70	107	4	GO:0045124
GeneOntologyBiologicalProcess	regulation of proteolysis	DAB2IP COL7A1 SFRP2 SPINT1 USP9X ADAM9 LDLRAD3 TSPAN5 WFIKKN2 SLPI LRP1 AHSG	5.02e-04	748	107	12	GO:0030162
GeneOntologyBiologicalProcess	regulation of hemopoiesis	SETD1A SFRP1 AXL KAT6A CD83 IL17D DLL1 FBN1 ZNF608 FSHR	5.04e-04	540	107	10	GO:1903706
GeneOntologyBiologicalProcess	tissue morphogenesis	SFRP1 SFRP2 SPINT1 ESRP1 DLL1 ZFPM2 TGFBR3 NFATC4 FMN1 MACF1 FST KDF1	5.14e-04	750	107	12	GO:0048729
GeneOntologyBiologicalProcess	cell-matrix adhesion	SFRP1 ADAM9 SVEP1 FMN1 LRP1 MACF1 CCN2	5.22e-04	270	107	7	GO:0007160
GeneOntologyBiologicalProcess	bone remodeling	SFRP1 TF FSHR AHSG LTBP3	5.26e-04	127	107	5	GO:0046849
GeneOntologyBiologicalProcess	negative regulation of Wnt signaling pathway	DAB2IP SFRP1 SFRP2 IGFBP4 NFATC4 LRP1	5.42e-04	195	107	6	GO:0030178
GeneOntologyBiologicalProcess	regulation of cell-substrate junction organization	SFRP1 FMN1 LRP1 MACF1	6.27e-04	75	107	4	GO:0150116
GeneOntologyBiologicalProcess	chondrocyte differentiation	COL2A1 SFRP2 CHRDL2 CCN2 LTBP3	6.49e-04	133	107	5	GO:0002062
GeneOntologyBiologicalProcess	collagen fibril organization	COL2A1 ADAMTS19 SFRP2 COL14A1	6.59e-04	76	107	4	GO:0030199
GeneOntologyBiologicalProcess	epidermis development	COL7A1 SPINT1 ESRP1 DLL1 SVEP1 CCN2 FST KDF1 USH2A	6.67e-04	461	107	9	GO:0008544
GeneOntologyBiologicalProcess	axon extension	DIP2B ARHGAP32 USP9X LRP1 MACF1	6.95e-04	135	107	5	GO:0048675
GeneOntologyBiologicalProcess	tricuspid valve morphogenesis	ADAMTS19 ZFPM2	7.31e-04	8	107	2	GO:0003186
GeneOntologyBiologicalProcess	convergent extension involved in axis elongation	SFRP1 SFRP2	7.31e-04	8	107	2	GO:0060028
GeneOntologyBiologicalProcess	negative regulation of transforming growth factor beta receptor signaling pathway	TGFBR3 FBN1 WFIKKN2 LRP1 ADAMTSL2	7.67e-04	138	107	5	GO:0030512
GeneOntologyBiologicalProcess	establishment of protein localization to extracellular region	CACNA1E SFRP1 ADAM9 SYBU PIM3 FBN1 AFM LRP1 LTBP2	9.27e-04	483	107	9	GO:0035592
GeneOntologyBiologicalProcess	tricuspid valve development	ADAMTS19 ZFPM2	9.37e-04	9	107	2	GO:0003175
GeneOntologyBiologicalProcess	negative regulation of non-canonical Wnt signaling pathway	SFRP1 SFRP2	9.37e-04	9	107	2	GO:2000051
GeneOntologyBiologicalProcess	regulation of cell adhesion	SELP SFRP1 SFRP2 ADAM9 CD83 DLL1 FBLN1 RASAL3 ZNF608 FMN1 LRP1 ADAMTS18 MACF1	1.02e-03	927	107	13	GO:0030155
GeneOntologyBiologicalProcess	protein localization to extracellular region	CACNA1E SFRP1 ADAM9 SYBU PIM3 FBN1 AFM LRP1 LTBP2	1.03e-03	490	107	9	GO:0071692
GeneOntologyBiologicalProcess	regulation of cell junction assembly	VLDLR SFRP1 USP9X ADGRB2 FMN1 LRP1 MACF1	1.15e-03	309	107	7	GO:1901888
GeneOntologyBiologicalProcess	circulatory system development	COL2A1 DAB2IP ADAMTS19 SFRP1 SFRP2 SPINT1 KAT6A ADGRB2 DLL1 SVEP1 ZFPM2 TGFBR3 FBN1 NFATC4 LRP1 COL14A1 CCN2	1.18e-03	1442	107	17	GO:0072359
GeneOntologyBiologicalProcess	regulation of insulin secretion	CACNA1E SFRP1 SYBU PIM3 FBN1 LRP1	1.30e-03	231	107	6	GO:0050796
GeneOntologyBiologicalProcess	stem cell proliferation	SETD1A SFRP2 FBLN1 LTBP3 KDF1	1.33e-03	156	107	5	GO:0072089
GeneOntologyBiologicalProcess	regulation of insulin secretion involved in cellular response to glucose stimulus	CACNA1E SYBU PIM3 LRP1	1.35e-03	92	107	4	GO:0061178
GeneOntologyBiologicalProcess	stem cell fate commitment	SFRP1 SFRP2	1.42e-03	11	107	2	GO:0048865
GeneOntologyBiologicalProcess	cellular response to X-ray	SFRP1 SFRP2	1.42e-03	11	107	2	GO:0071481
GeneOntologyBiologicalProcess	heart morphogenesis	COL2A1 ADAMTS19 SFRP2 KAT6A DLL1 ZFPM2 TGFBR3	1.43e-03	321	107	7	GO:0003007
GeneOntologyBiologicalProcess	positive regulation of developmental growth	ARHGAP32 DLL1 ZFPM2 TGFBR3 LRP1 MACF1	1.52e-03	238	107	6	GO:0048639
GeneOntologyBiologicalProcess	sensory perception of mechanical stimulus	COL2A1 P2RX4 OTOGL SCN1A KCNQ2 USH2A	1.52e-03	238	107	6	GO:0050954
GeneOntologyBiologicalProcess	vasculature development	DAB2IP SFRP1 SFRP2 SPINT1 KAT6A ADGRB2 DLL1 SVEP1 ZFPM2 TGFBR3 NFATC4 LRP1 CCN2	1.52e-03	969	107	13	GO:0001944
GeneOntologyBiologicalProcess	regulation of JNK cascade	DAB2IP SFRP1 SFRP2 TGFBR3 CCN2	1.53e-03	161	107	5	GO:0046328
GeneOntologyBiologicalProcess	inner ear receptor cell differentiation	ESRP1 DLL1 OTOGL USH2A	1.58e-03	96	107	4	GO:0060113
GeneOntologyBiologicalProcess	regulation of developmental growth	DIP2B ARHGAP32 DLL1 ZFPM2 TGFBR3 LRP1 MACF1 COL14A1	1.58e-03	421	107	8	GO:0048638
GeneOntologyCellularComponent	extracellular matrix	COL2A1 THSD4 ADAMTS19 COL7A1 SFRP1 SFRP2 SSPOP TF SVEP1 FBLN1 FBN1 OTOGL SLPI AHSG ADAMTS18 COL14A1 CCN2 LTBP2 LTBP3 USH2A ADAMTSL2	1.28e-11	656	106	21	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL2A1 THSD4 ADAMTS19 COL7A1 SFRP1 SFRP2 SSPOP TF SVEP1 FBLN1 FBN1 OTOGL SLPI AHSG ADAMTS18 COL14A1 CCN2 LTBP2 LTBP3 USH2A ADAMTSL2	1.36e-11	658	106	21	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL2A1 THSD4 COL7A1 SFRP1 SFRP2 SSPOP TF FBLN1 FBN1 SLPI AHSG COL14A1 CCN2 LTBP2 LTBP3 USH2A	1.05e-08	530	106	16	GO:0062023
GeneOntologyCellularComponent	basement membrane	COL2A1 COL7A1 TF FBLN1 FBN1 USH2A	3.70e-05	122	106	6	GO:0005604
GeneOntologyCellularComponent	anchoring collagen complex	COL7A1 COL14A1	7.62e-05	3	106	2	GO:0030934
GeneOntologyCellularComponent	endoplasmic reticulum lumen	COL2A1 COL7A1 TF TSPAN5 FBN1 IGFBP4 AHSG COL14A1	2.91e-04	332	106	8	GO:0005788
GeneOntologyCellularComponent	dense body	SYBU TF	5.26e-04	7	106	2	GO:0097433
HumanPheno	Ovoid vertebral bodies	COL2A1 SGSH FBN1 LTBP3 ADAMTSL2	7.83e-06	34	43	5	HP:0003300
MousePheno	abnormal limb morphology	COL2A1 COL7A1 SFRP2 CRIM1 SGSH TMPRSS6 AFF3 ESRP1 SVEP1 TGFBR3 FBN1 RASAL3 FMN1 AFM WFIKKN2 FSHR ARID5B LRP1 AHSG CCN2 FST KDF1 ADAMTSL2	2.12e-07	1028	94	23	MP:0002109
MousePheno	limbs/digits/tail phenotype	COL2A1 COL7A1 SFRP2 CRIM1 SGSH TMPRSS6 KAT6A AFF3 ESRP1 DLL1 SVEP1 TGFBR3 FBN1 RASAL3 FMN1 AFM WFIKKN2 FSHR ARID5B LRP1 AHSG CCN2 FST KDF1 ADAMTSL2	5.26e-07	1258	94	25	MP:0005371
MousePheno	abnormal appendicular skeleton morphology	COL2A1 COL7A1 SFRP2 ORC3 SGSH TMPRSS6 AFF3 SSPOP TGFBR3 FBN1 RASAL3 P2RX4 FMN1 FSHR ARID5B AHSG CCN2 LTBP3 FST ADAMTSL2	1.61e-06	896	94	20	MP:0009250
MousePheno	abnormal long bone morphology	COL2A1 COL7A1 SFRP2 SGSH TMPRSS6 AFF3 TGFBR3 FBN1 RASAL3 P2RX4 FMN1 FSHR ARID5B AHSG CCN2 LTBP3 ADAMTSL2	2.27e-06	676	94	17	MP:0003723
MousePheno	abnormal hindlimb morphology	COL2A1 SGSH TMPRSS6 AFF3 TGFBR3 FBN1 RASAL3 FMN1 WFIKKN2 FSHR ARID5B AHSG CCN2 FST KDF1	6.37e-06	576	94	15	MP:0000556
MousePheno	abnormal secondary palate morphology	COL2A1 BNC2 KAT6A ESRP1 TGFBR3 ARID5B CCN2 FST	1.14e-05	159	94	8	MP:0013550
MousePheno	abnormal vertebrae morphology	COL2A1 SFRP2 CRIM1 SGSH KAT6A AFF3 DLL1 FBN1 FSHR ARID5B CCN2 PYY3 LTBP3 FST	1.60e-05	546	94	14	MP:0000137
MousePheno	decreased length of long bones	COL2A1 SFRP2 SGSH TMPRSS6 AFF3 FBN1 RASAL3 FMN1 ARID5B AHSG LTBP3 ADAMTSL2	1.83e-05	409	94	12	MP:0004686
MousePheno	abnormal presacral vertebrae morphology	COL2A1 KAT6A DLL1 FBN1 FSHR CCN2 PYY3 LTBP3 FST	2.01e-05	225	94	9	MP:0000459
MousePheno	cleft secondary palate	COL2A1 BNC2 KAT6A ESRP1 TGFBR3 CCN2 FST	2.30e-05	127	94	7	MP:0009890
MousePheno	abnormal aortic sinus morphology	THSD4 FBN1	4.47e-05	2	94	2	MP:0010482
MousePheno	abnormal thoracic cage morphology	COL2A1 SETD1A CRIM1 KAT6A SSPOP TGFBR3 FBN1 FSHR ARID5B CCN2 LTBP3 FST	6.14e-05	463	94	12	MP:0004624
MousePheno	abnormal vertebral column morphology	COL2A1 SFRP2 CRIM1 SGSH KAT6A AFF3 DLL1 SSPOP FBLN1 FBN1 FSHR ARID5B CCN2 PYY3 LTBP3 FST	6.46e-05	787	94	16	MP:0004703
MousePheno	abnormal skin appearance	COL7A1 CRIM1 TMPRSS6 KAT6A TF SVEP1 ZFPM2 FBLN1 FBN1 FSHR FST KDF1	7.54e-05	473	94	12	MP:0009931
MousePheno	tight skin	FBN1 FST KDF1	1.02e-04	14	94	3	MP:0001198
MousePheno	abnormal limb long bone morphology	COL2A1 SFRP2 SGSH TMPRSS6 AFF3 TGFBR3 FBN1 RASAL3 FMN1 FSHR ARID5B AHSG CCN2	1.05e-04	568	94	13	MP:0011504
MousePheno	abnormal habituation to a novel odor	ARHGAP32 SCN1A	1.34e-04	3	94	2	MP:0011622
MousePheno	abnormal limb bone morphology	COL2A1 SFRP2 SGSH TMPRSS6 AFF3 TGFBR3 FBN1 RASAL3 FMN1 FSHR ARID5B AHSG CCN2	1.46e-04	587	94	13	MP:0002115
MousePheno	abnormal palatal shelf morphology	COL2A1 BNC2 ESRP1 TGFBR3 CCN2 KDF1	1.63e-04	121	94	6	MP:0031460
MousePheno	abnormal secondary palate development	COL2A1 BNC2 ESRP1 TGFBR3 CCN2 KDF1	1.86e-04	124	94	6	MP:0009655
MousePheno	abnormal tibia morphology	COL2A1 SGSH TMPRSS6 AFF3 FBN1 RASAL3 FMN1 ARID5B AHSG CCN2	2.09e-04	375	94	10	MP:0000558
MousePheno	abnormal forelimb morphology	COL2A1 SFRP2 TGFBR3 FBN1 FMN1 CCN2 KDF1	2.23e-04	182	94	7	MP:0000550
MousePheno	abnormal radius morphology	COL2A1 SFRP2 FBN1 FMN1 CCN2	2.24e-04	82	94	5	MP:0000552
MousePheno	abnormal palate development	COL2A1 BNC2 ESRP1 TGFBR3 CCN2 KDF1	2.30e-04	129	94	6	MP:0009653
MousePheno	abnormal hindlimb zeugopod morphology	COL2A1 SGSH TMPRSS6 AFF3 FBN1 RASAL3 FMN1 ARID5B AHSG CCN2	2.37e-04	381	94	10	MP:0003857
MousePheno	lethality during fetal growth through weaning, complete penetrance	COL2A1 BNC2 COL7A1 CRIM1 KAT6A ESRP1 DLL1 TF ZFPM2 ZFX TGFBR3 FBLN1 FBN1 SCN1A FSHR LRP1 KCNQ2 CCN2 FST KDF1	2.45e-04	1269	94	20	MP:0011111
MousePheno	abnormal ulna morphology	COL2A1 SFRP2 FBN1 FMN1 CCN2	2.51e-04	84	94	5	MP:0005108
MousePheno	abnormal palate morphology	COL2A1 BNC2 KAT6A ESRP1 TGFBR3 ARID5B CCN2 FST KDF1	3.05e-04	321	94	9	MP:0003755
MousePheno	abnormal digit morphology	COL2A1 COL7A1 SFRP2 CRIM1 AFF3 ESRP1 FBN1 FMN1 AFM	3.19e-04	323	94	9	MP:0002110
MousePheno	abnormal fibula morphology	COL2A1 AFF3 FMN1 CCN2	3.76e-04	51	94	4	MP:0002187
MousePheno	abnormal nose morphology	COL2A1 FBLN1 ARID5B CCN2 LTBP3 FST KDF1	4.07e-04	201	94	7	MP:0002233
MousePheno	abnormal maxilla morphology	COL2A1 BNC2 ESRP1 FBLN1 ARID5B LTBP3	4.16e-04	144	94	6	MP:0000455
MousePheno	abnormal right lung accessory lobe morphology	ZFPM2 ADAMTS18	4.42e-04	5	94	2	MP:0009571
MousePheno	perinatal lethality	COL2A1 BNC2 CRIM1 KAT6A ESRP1 DLL1 ZFX FBLN1 FMN1 SCN1A FSHR ARID5B LRP1 KCNQ2 CCN2 FST KDF1 ADAMTSL2	4.66e-04	1130	94	18	MP:0002081
MousePheno	hemorrhage	COL2A1 SELP CRIM1 KAT6A ESRP1 DLL1 ZFPM2 TGFBR3 FBLN1 FBN1 XPO5 FSHR LRP1	4.82e-04	664	94	13	MP:0001914
MousePheno	short tibia	COL2A1 SGSH TMPRSS6 FBN1 RASAL3 FMN1 ARID5B AHSG	5.10e-04	274	94	8	MP:0002764
MousePheno	abnormal craniofacial development	COL2A1 BNC2 CRIM1 KAT6A ESRP1 TGFBR3 CCN2 LTBP3 FST KDF1	5.62e-04	425	94	10	MP:0003935
MousePheno	abnormal axial skeleton morphology	COL2A1 SETD1A BNC2 SFRP2 CRIM1 SGSH KAT6A AFF3 ESRP1 DLL1 SSPOP TGFBR3 FBLN1 FBN1 FSHR ARID5B CCN2 PYY3 LTBP3 FST ADAMTSL2	5.66e-04	1458	94	21	MP:0002114
MousePheno	abnormal forelimb zeugopod morphology	COL2A1 SFRP2 FBN1 FMN1 CCN2	6.15e-04	102	94	5	MP:0003855
MousePheno	lens dislocation	CRIM1 LTBP2	6.59e-04	6	94	2	MP:0031428
MousePheno	cleft palate	COL2A1 BNC2 KAT6A ESRP1 TGFBR3 CCN2 FST KDF1	7.24e-04	289	94	8	MP:0000111
MousePheno	abnormal respiratory system development	ESRP1 ZFPM2 FBLN1 FBN1 ADAMTS18 CCN2	7.27e-04	160	94	6	MP:0003115
MousePheno	oral cleft	COL2A1 BNC2 KAT6A ESRP1 TGFBR3 CCN2 FST KDF1	7.58e-04	291	94	8	MP:0021164
MousePheno	abnormal jaw morphology	COL2A1 BNC2 KAT6A AFF3 ESRP1 FBLN1 FBN1 ARID5B CCN2 LTBP3 FST	8.40e-04	530	94	11	MP:0000454
Domain	Growth_fac_rcpt_	VLDLR CRIM1 DLL1 LRP1B SVEP1 FBLN1 FBN1 IGFBP4 UMODL1 LRP1 CCN2 LTBP2 LTBP3	4.74e-12	156	106	13	IPR009030
Domain	EGF_1	SELP VLDLR ADAM18 ADAM9 DLL1 SSPOP LRP1B SVEP1 FBLN1 FBN1 UMODL1 LRP1 LTBP2 LTBP3 USH2A	1.52e-11	255	106	15	PS00022
Domain	EGF_3	SELP VLDLR ADAM18 ADAM9 DLL1 SSPOP LRP1B SVEP1 FBLN1 FBN1 UMODL1 LRP1 LTBP2 LTBP3	6.42e-11	235	106	14	PS50026
Domain	EGF_Ca-bd_CS	VLDLR DLL1 LRP1B SVEP1 FBLN1 FBN1 UMODL1 LRP1 LTBP2 LTBP3	1.88e-10	97	106	10	IPR018097
Domain	EGF_CA	VLDLR DLL1 LRP1B SVEP1 FBLN1 FBN1 UMODL1 LRP1 LTBP2 LTBP3	2.30e-10	99	106	10	PS01187
Domain	ASX_HYDROXYL	VLDLR DLL1 LRP1B SVEP1 FBLN1 FBN1 UMODL1 LRP1 LTBP2 LTBP3	2.55e-10	100	106	10	PS00010
Domain	EGF_2	SELP VLDLR ADAM18 ADAM9 DLL1 SSPOP LRP1B SVEP1 FBLN1 FBN1 UMODL1 LRP1 LTBP2 LTBP3	3.14e-10	265	106	14	PS01186
Domain	EGF-type_Asp/Asn_hydroxyl_site	VLDLR DLL1 LRP1B SVEP1 FBLN1 FBN1 UMODL1 LRP1 LTBP2 LTBP3	4.56e-10	106	106	10	IPR000152
Domain	EGF_CA	VLDLR LRP1B SVEP1 FBLN1 FBN1 UMODL1 LRP1 LTBP2 LTBP3	1.38e-09	86	106	9	PF07645
Domain	EGF-like_dom	SELP VLDLR ADAM18 ADAM9 DLL1 LRP1B SVEP1 FBLN1 FBN1 UMODL1 LRP1 LTBP2 LTBP3	1.63e-09	249	106	13	IPR000742
Domain	EGF_CA	VLDLR DLL1 LRP1B SVEP1 FBLN1 FBN1 UMODL1 LRP1 LTBP2 LTBP3	1.83e-09	122	106	10	SM00179
Domain	EGF-like_Ca-bd_dom	VLDLR DLL1 LRP1B SVEP1 FBLN1 FBN1 UMODL1 LRP1 LTBP2 LTBP3	2.15e-09	124	106	10	IPR001881
Domain	EGF-like_CS	SELP VLDLR ADAM18 ADAM9 DLL1 LRP1B SVEP1 FBLN1 FBN1 UMODL1 LRP1 LTBP2 LTBP3	2.88e-09	261	106	13	IPR013032
Domain	Ldl_recept_a	VLDLR SPINT1 TMPRSS6 LDLRAD3 SSPOP LRP1B LRP1	5.90e-09	45	106	7	PF00057
Domain	-	VLDLR SPINT1 TMPRSS6 LDLRAD3 SSPOP LRP1B LRP1	6.93e-09	46	106	7	4.10.400.10
Domain	EGF	SELP VLDLR ADAM9 DLL1 LRP1B SVEP1 FBLN1 FBN1 UMODL1 LRP1 LTBP2 LTBP3	9.22e-09	235	106	12	SM00181
Domain	LDLRA_1	VLDLR SPINT1 TMPRSS6 LDLRAD3 SSPOP LRP1B LRP1	9.44e-09	48	106	7	PS01209
Domain	LDrepeatLR_classA_rpt	VLDLR SPINT1 TMPRSS6 LDLRAD3 SSPOP LRP1B LRP1	1.10e-08	49	106	7	IPR002172
Domain	LDLa	VLDLR SPINT1 TMPRSS6 LDLRAD3 SSPOP LRP1B LRP1	1.10e-08	49	106	7	SM00192
Domain	LDLRA_2	VLDLR SPINT1 TMPRSS6 LDLRAD3 SSPOP LRP1B LRP1	1.10e-08	49	106	7	PS50068
Domain	TSP_1	THSD4 ADAMTS19 ADGRB2 SSPOP ADAMTS18 CCN2 ADAMTSL2	6.62e-08	63	106	7	PF00090
Domain	TSP1	THSD4 ADAMTS19 ADGRB2 SSPOP ADAMTS18 CCN2 ADAMTSL2	8.25e-08	65	106	7	SM00209
Domain	TSP1_rpt	THSD4 ADAMTS19 ADGRB2 SSPOP ADAMTS18 CCN2 ADAMTSL2	8.25e-08	65	106	7	IPR000884
Domain	TSP1	THSD4 ADAMTS19 ADGRB2 SSPOP ADAMTS18 CCN2 ADAMTSL2	8.25e-08	65	106	7	PS50092
Domain	LDLR_class-A_CS	VLDLR SPINT1 LDLRAD3 SSPOP LRP1B LRP1	9.51e-08	40	106	6	IPR023415
Domain	TB_dom	FBN1 LTBP2 LTBP3 FST	1.21e-07	9	106	4	IPR017878
Domain	TB	FBN1 LTBP2 LTBP3 FST	1.21e-07	9	106	4	PS51364
Domain	cEGF	LRP1B FBLN1 FBN1 LRP1 LTBP3	3.20e-07	26	106	5	PF12662
Domain	cEGF	LRP1B FBLN1 FBN1 LRP1 LTBP3	3.20e-07	26	106	5	IPR026823
Domain	PLAC	THSD4 ADAMTS19 ADAMTS18 ADAMTSL2	9.39e-07	14	106	4	PF08686
Domain	VWFC_1	COL2A1 CHRDL2 CRIM1 SSPOP CCN2	1.75e-06	36	106	5	PS01208
Domain	VWFC_2	COL2A1 CHRDL2 CRIM1 SSPOP CCN2	2.32e-06	38	106	5	PS50184
Domain	VWC	COL2A1 CHRDL2 CRIM1 SSPOP CCN2	2.32e-06	38	106	5	SM00214
Domain	PLAC	THSD4 ADAMTS19 ADAMTS18 ADAMTSL2	3.56e-06	19	106	4	PS50900
Domain	PLAC	THSD4 ADAMTS19 ADAMTS18 ADAMTSL2	3.56e-06	19	106	4	IPR010909
Domain	VWF_dom	COL2A1 CHRDL2 CRIM1 SSPOP CCN2	3.85e-06	42	106	5	IPR001007
Domain	TB	FBN1 LTBP2 LTBP3	6.12e-06	7	106	3	PF00683
Domain	EGF	SELP VLDLR DLL1 LRP1B SVEP1 LRP1 LTBP2	7.54e-06	126	106	7	PF00008
Domain	ADAM_spacer1	THSD4 ADAMTS19 ADAMTS18 ADAMTSL2	7.99e-06	23	106	4	IPR010294
Domain	ADAM_spacer1	THSD4 ADAMTS19 ADAMTS18 ADAMTSL2	7.99e-06	23	106	4	PF05986
Domain	-	FBN1 LTBP2 LTBP3	9.75e-06	8	106	3	3.90.290.10
Domain	VWC	COL2A1 CHRDL2 CRIM1 CCN2	1.81e-05	28	106	4	PF00093
Domain	EGF_extracell	ADAM18 ADAM9 LRP1B SVEP1 LTBP2	2.28e-05	60	106	5	IPR013111
Domain	EGF_2	ADAM18 ADAM9 LRP1B SVEP1 LTBP2	2.28e-05	60	106	5	PF07974
Domain	DUF5050	LRP1B LRP1	3.19e-05	2	106	2	IPR032485
Domain	DUF5050	LRP1B LRP1	3.19e-05	2	106	2	PF16472
Domain	Ldl_recept_b	VLDLR LRP1B LRP1	6.18e-05	14	106	3	PF00058
Domain	LDLRB	VLDLR LRP1B LRP1	6.18e-05	14	106	3	PS51120
Domain	Pep_M12B_propep	ADAMTS19 ADAM18 ADAM9 ADAMTS18	6.92e-05	39	106	4	PF01562
Domain	Peptidase_M12B_N	ADAMTS19 ADAM18 ADAM9 ADAMTS18	6.92e-05	39	106	4	IPR002870
Domain	DISINTEGRIN_1	ADAMTS19 ADAM18 ADAM9 ADAMTS18	7.65e-05	40	106	4	PS00427
Domain	Reprolysin	ADAMTS19 ADAM18 ADAM9 ADAMTS18	7.65e-05	40	106	4	PF01421
Domain	ADAM_MEPRO	ADAMTS19 ADAM18 ADAM9 ADAMTS18	7.65e-05	40	106	4	PS50215
Domain	DISINTEGRIN_2	ADAMTS19 ADAM18 ADAM9 ADAMTS18	7.65e-05	40	106	4	PS50214
Domain	Peptidase_M12B	ADAMTS19 ADAM18 ADAM9 ADAMTS18	7.65e-05	40	106	4	IPR001590
Domain	LY	VLDLR LRP1B LRP1	7.69e-05	15	106	3	SM00135
Domain	LDLR_classB_rpt	VLDLR LRP1B LRP1	7.69e-05	15	106	3	IPR000033
Domain	Disintegrin_dom	ADAMTS19 ADAM18 ADAM9 ADAMTS18	8.44e-05	41	106	4	IPR001762
Domain	WAP	UMODL1 WFIKKN2 SLPI	9.43e-05	16	106	3	SM00217
Domain	WAP	UMODL1 WFIKKN2 SLPI	9.43e-05	16	106	3	PF00095
Domain	-	UMODL1 WFIKKN2 SLPI	1.14e-04	17	106	3	4.10.75.10
Domain	WAP	UMODL1 WFIKKN2 SLPI	1.14e-04	17	106	3	PS51390
Domain	IB	CRIM1 IGFBP4 CCN2	1.36e-04	18	106	3	SM00121
Domain	-	COL7A1 SPINT1 WFIKKN2	1.36e-04	18	106	3	4.10.410.10
Domain	Prtase_inh_Kunz-CS	COL7A1 SPINT1 WFIKKN2	1.36e-04	18	106	3	IPR020901
Domain	NTR	SFRP1 SFRP2 WFIKKN2	1.61e-04	19	106	3	PF01759
Domain	Netrin_module_non-TIMP	SFRP1 SFRP2 WFIKKN2	1.61e-04	19	106	3	IPR018933
Domain	BPTI_KUNITZ_1	COL7A1 SPINT1 WFIKKN2	1.61e-04	19	106	3	PS00280
Domain	BPTI_KUNITZ_2	COL7A1 SPINT1 WFIKKN2	1.61e-04	19	106	3	PS50279
Domain	Kunitz_BPTI	COL7A1 SPINT1 WFIKKN2	1.61e-04	19	106	3	PF00014
Domain	IGFBP	CRIM1 IGFBP4 CCN2	1.89e-04	20	106	3	PF00219
Domain	IGFBP-like	CRIM1 IGFBP4 CCN2	1.89e-04	20	106	3	IPR000867
Domain	IGFBP_N_2	CRIM1 IGFBP4 CCN2	1.89e-04	20	106	3	PS51323
Domain	WAP_dom	UMODL1 WFIKKN2 SLPI	2.53e-04	22	106	3	IPR008197
Domain	NTR	SFRP1 SFRP2 WFIKKN2	2.90e-04	23	106	3	PS50189
Domain	Netrin_domain	SFRP1 SFRP2 WFIKKN2	2.90e-04	23	106	3	IPR001134
Domain	Kunitz_BPTI	COL7A1 SPINT1 WFIKKN2	2.90e-04	23	106	3	IPR002223
Domain	fn3	BOC COL7A1 AXL UMODL1 COL14A1 USH2A	3.24e-04	162	106	6	PF00041
Domain	Peptidase_M12B_ADAM-TS	ADAMTS19 ADAMTS18 ADAMTSL2	3.30e-04	24	106	3	IPR013273
Domain	TIMP-like_OB-fold	SFRP1 SFRP2 WFIKKN2	4.20e-04	26	106	3	IPR008993
Domain	ADAM_Cys-rich	ADAMTS19 ADAM18 ADAM9	4.71e-04	27	106	3	IPR006586
Domain	ACR	ADAMTS19 ADAM18 ADAM9	4.71e-04	27	106	3	SM00608
Domain	hEGF	DLL1 SVEP1 LTBP3	5.25e-04	28	106	3	PF12661
Domain	FN3	BOC COL7A1 AXL UMODL1 COL14A1 USH2A	6.55e-04	185	106	6	SM00060
Domain	FN3	BOC COL7A1 AXL UMODL1 COL14A1 USH2A	9.57e-04	199	106	6	PS50853
Domain	-	ADAMTS19 ADAM18 ADAM9 ADAMTS18	1.17e-03	81	106	4	3.40.390.10
Domain	MetalloPept_cat_dom	ADAMTS19 ADAM18 ADAM9 ADAMTS18	1.17e-03	81	106	4	IPR024079
Domain	FN3_dom	BOC COL7A1 AXL UMODL1 COL14A1 USH2A	1.23e-03	209	106	6	IPR003961
Domain	-	VLDLR LRP1B LRP1	1.40e-03	39	106	3	2.120.10.30
Domain	Rho_GTPase_activation_prot	DAB2IP ARHGAP32 RASAL3 ARHGAP45	1.59e-03	88	106	4	IPR008936
Domain	SET	SETD1A EZH1 NSD3	1.62e-03	41	106	3	PF00856
Domain	Insulin_GF-bd_Cys-rich_CS	IGFBP4 CCN2	1.70e-03	11	106	2	IPR017891
Domain	IGFBP_N_1	IGFBP4 CCN2	2.03e-03	12	106	2	PS00222
Domain	SET	SETD1A EZH1 NSD3	2.26e-03	46	106	3	SM00317
Domain	6-blade_b-propeller_TolB-like	VLDLR LRP1B LRP1	2.26e-03	46	106	3	IPR011042
Domain	RasGAP	DAB2IP RASAL3	2.78e-03	14	106	2	SM00323
Domain	ZP_2	TGFBR3 UMODL1	2.78e-03	14	106	2	PS51034
Domain	ZP_1	TGFBR3 UMODL1	2.78e-03	14	106	2	PS00682
Domain	RasGAP_CS	DAB2IP RASAL3	2.78e-03	14	106	2	IPR023152
Domain	SET_dom	SETD1A EZH1 NSD3	2.87e-03	50	106	3	IPR001214
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD4 ADAMTS19 SSPOP ADAMTS18 ADAMTSL2	2.73e-06	39	81	5	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD4 ADAMTS19 SSPOP ADAMTS18 ADAMTSL2	2.73e-06	39	81	5	MM15165
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL2A1 COL7A1 ADAM9 TMPRSS6 FBLN1 FBN1 ADAMTS18 COL14A1 LTBP2 LTBP3	8.11e-06	300	81	10	M610
Pathway	WP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE	TGFBR3 FBN1 CCN2 LTBP2	1.17e-05	25	81	4	M39713
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL2A1 COL7A1 ADAM9 TMPRSS6 FBN1 ADAMTS18 COL14A1	1.54e-05	140	81	7	M587
Pathway	WP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS	TGFBR3 FBN1 LTBP3 FST ADAMTSL2	2.17e-05	59	81	5	M39886
Pathway	REACTOME_COLLAGEN_DEGRADATION	COL2A1 COL7A1 ADAM9 TMPRSS6 COL14A1	3.23e-05	64	81	5	M26953
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	THSD4 ADAMTS19 SSPOP ADAMTS18 ADAMTSL2	4.34e-05	68	81	5	M27303
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBLN1 FBN1 LTBP2 LTBP3	5.78e-05	37	81	4	M27134
Pathway	REACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS	USP9X TGFBR3 FBN1 LTBP2 LTBP3 FST	5.89e-05	118	81	6	MM15588
Pathway	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS	TGFBR3 FBN1 LTBP2 LTBP3	6.44e-05	38	81	4	MM14874
Pathway	REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX	USP9X TGFBR3 FBN1 LTBP2 LTBP3	7.90e-05	77	81	5	MM14670
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBLN1 FBN1 LTBP2 LTBP3	1.15e-04	44	81	4	M26969
Pathway	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS	TGFBR3 FBN1 LTBP2 LTBP3	1.50e-04	47	81	4	M646
Pathway	REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX	USP9X TGFBR3 FBN1 LTBP2 LTBP3	2.03e-04	94	81	5	M1041
Pathway	REACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS	USP9X TGFBR3 FBN1 LTBP2 LTBP3 FST	3.24e-04	161	81	6	M27871
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD4 ADAMTS19 SSPOP ADAMTS18 ADAMTSL2	4.05e-04	109	81	5	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD4 ADAMTS19 SSPOP ADAMTS18 ADAMTSL2	4.40e-04	111	81	5	M27416
Pathway	REACTOME_DISEASES_OF_METABOLISM	THSD4 ADAMTS19 SGSH SSPOP ADAMTS18 LMBRD1 ADAMTSL2	5.78e-04	250	81	7	M27554
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL2A1 COL7A1 TMPRSS6 FBN1 COL14A1 LTBP2 LTBP3	6.96e-04	258	81	7	MM14572
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBN1 LTBP2 LTBP3	8.04e-04	32	81	3	MM14854
Pathway	KEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA	FBN1 LTBP3	8.93e-04	8	81	2	M47850
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	THSD4 ADAMTS19 SSPOP ADAMTS18 ADAMTSL2	1.38e-03	143	81	5	M27275
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBN1 LTBP2 LTBP3	1.44e-03	39	81	3	MM14601
Pathway	PID_AMB2_NEUTROPHILS_PATHWAY	SELP LRP1 CCN2	1.66e-03	41	81	3	M159
Pathway	REACTOME_COLLAGEN_CHAIN_TRIMERIZATION	COL2A1 COL7A1 COL14A1	1.66e-03	41	81	3	MM15538
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	THSD4 ADAMTS19 ADGRB2 SSPOP ADAMTS18 CCN2 ADAMTSL2	4.62e-09	75	111	7	20637190
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	SFRP1 ADAM9 SVEP1 FBLN1 FBN1 IGFBP4 COL14A1 CCN2 LTBP2 FST	7.78e-09	248	111	10	24006456
Pubmed	Geleophysic Dysplasia	FBN1 LTBP3 ADAMTSL2	3.16e-08	3	111	3	20301776
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	COL2A1 FBLN1 FBN1 COL14A1 CCN2 LTBP2	3.52e-07	86	111	6	28327460
Pubmed	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	SFRP1 SFRP2 CHRDL2 TGFBR3 IGFBP4 AHSG CCN2 LTBP2 LTBP3 FST	4.48e-07	383	111	10	19453261
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	COL2A1 FBLN1 FBN1 AHSG COL14A1 LTBP2 LTBP3	4.69e-07	146	111	7	27068509
Pubmed	Proteomics characterization of extracellular space components in the human aorta.	SFRP1 FBLN1 FBN1 SLPI COL14A1 LTBP2	9.13e-07	101	111	6	20551380
Pubmed	Mapping Extracellular Protein-Protein Interactions Using Extracellular Proximity Labeling (ePL).	COL2A1 CRIM1 TF FBLN1 FBN1 AHSG CCN2 LTBP3	1.36e-06	247	111	8	39238192
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	COL7A1 CCPG1 CRIM1 AXL SGSH ADAM9 LRP1B FBLN1 FBN1 IGFBP4 ZDHHC6 SLPI LRP1 CCN2 LTBP2 LTBP3	1.39e-06	1201	111	16	35696571
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	GPRASP1 CRIM1 FBLN1 FBN1 LRP1 LTBP3	2.27e-06	118	111	6	21078624
Pubmed	Limb- and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia.	COL2A1 FBN1 ADAMTSL2	3.74e-06	10	111	3	30738849
Pubmed	Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.	VLDLR SFRP2 TTK FBLN1 IGFBP4 ADAMTS18	3.99e-06	130	111	6	28705898
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL2A1 COL7A1 FBLN1 FBN1 SLPI COL14A1	4.96e-06	135	111	6	28675934
Pubmed	Correct dosage of Fog2 and Gata4 transcription factors is critical for fetal testis development in mice.	ADAMTS19 ZFPM2 FST	6.82e-06	12	111	3	17848526
Pubmed	Striking differences of LDL receptor-related protein 1B expression in mouse and human.	LRP1B LRP1	1.01e-05	2	111	2	15963947
Pubmed	Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome.	FBN1 LTBP3	1.01e-05	2	111	2	26494287
Pubmed	Wnt modulators, SFRP-1, and SFRP-2 are expressed in osteoblasts and differentially regulate hematopoietic stem cells.	SFRP1 SFRP2	1.01e-05	2	111	2	19778523
Pubmed	Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein.	LTBP2 LTBP3	1.01e-05	2	111	2	7798248
Pubmed	Exome sequencing identified new mutations in a Marfan syndrome family.	FBN1 LRP1	1.01e-05	2	111	2	24484584
Pubmed	ADAMTSL6β protein rescues fibrillin-1 microfibril disorder in a Marfan syndrome mouse model through the promotion of fibrillin-1 assembly.	THSD4 FBN1	1.01e-05	2	111	2	21880733
Pubmed	Hypermethylated Promoters of Secreted Frizzled-Related Protein Genes are Associated with Colorectal Cancer.	SFRP1 SFRP2	1.01e-05	2	111	2	30368728
Pubmed	Low density lipoprotein receptor-related protein (LRP) is a heparin-dependent adhesion receptor for connective tissue growth factor (CTGF) in rat activated hepatic stellate cells.	LRP1 CCN2	1.01e-05	2	111	2	14585398
Pubmed	EVALUATION OF FETUIN-A LEVEL IN POLYCYSTIC OVARY SYNDROME AND ITS ASSOCIATION WITH ASPROSIN AND SOME BIOCHEMICAL PARAMETERS.	FBN1 AHSG	1.01e-05	2	111	2	38096518
Pubmed	Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups.	TGFBR3 ADAMTS18	1.01e-05	2	111	2	19249006
Pubmed	Absence of LTBP-3 attenuates the aneurysmal phenotype but not spinal effects on the aorta in Marfan syndrome.	FBN1 LTBP3	1.01e-05	2	111	2	30306291
Pubmed	Confocal microscopy demonstrates association of LTBP-2 in fibrillin-1 microfibrils and colocalisation with perlecan in the disc cell pericellular matrix.	FBN1 LTBP2	1.01e-05	2	111	2	24867584
Pubmed	Inhibition of myoblast differentiation by Sfrp1 and Sfrp2.	SFRP1 SFRP2	1.01e-05	2	111	2	18322704
Pubmed	A novel USP9X substrate TTK contributes to tumorigenesis in non-small-cell lung cancer.	USP9X TTK	1.01e-05	2	111	2	29721084
Pubmed	Ubiquitous Gasp1 overexpression in mice leads mainly to a hypermuscular phenotype.	GPRASP1 WFIKKN2	1.01e-05	2	111	2	23046573
Pubmed	8-Cysteine TGF-BP structural motifs are the site of covalent binding between mouse LTBP-3, LTBP-2, and latent TGF-beta 1.	LTBP2 LTBP3	1.01e-05	2	111	2	9602168
Pubmed	LTBP3 Pathogenic Variants Predispose Individuals to Thoracic Aortic Aneurysms and Dissections.	FBN1 LTBP3	1.01e-05	2	111	2	29625025
Pubmed	Case-control association study of rare nonsynonymous variants of SCN1A and KCNQ2 in acute encephalopathy with biphasic seizures and late reduced diffusion.	SCN1A KCNQ2	1.01e-05	2	111	2	32276107
Pubmed	Change in gene expression profiles of secreted frizzled-related proteins (SFRPs) by sodium butyrate in gastric cancers: induction of promoter demethylation and histone modification causing inhibition of Wnt signaling.	SFRP1 SFRP2	1.01e-05	2	111	2	22246241
Pubmed	Clearance of coagulation factor VIII in very low-density lipoprotein receptor knockout mice.	VLDLR LRP1	1.01e-05	2	111	2	15327526
Pubmed	Verifying AXL and putative proteins as SARS-CoV-2 receptors by DnaE intein-based rapid cell-cell fusion assay.	AXL LDLRAD3	1.01e-05	2	111	2	37461287
Pubmed	ADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formation.	THSD4 FBN1	1.01e-05	2	111	2	19940141
Pubmed	Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.	VLDLR LRP1B LRP1	1.12e-05	14	111	3	15082773
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	COL7A1 ARHGAP32 ZSCAN12 USP9X NPIPA7 DENND3 SVEP1 ARFGEF3 TRANK1 ZDHHC6	1.15e-05	552	111	10	10737800
Pubmed	Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2.	GPRASP1 WFIKKN2 FST	1.40e-05	15	111	3	24019467
Pubmed	Human colostrum: identification of minor proteins in the aqueous phase by proteomics.	CHRDL2 SPINT1 TF TGFBR3 AFM AHSG	1.41e-05	162	111	6	16502470
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PLEKHB2 GPRASP1 VLDLR CRIM1 USP9X ADAM9 LRP1B TF FBN1 ARID5B LRP1 KCNQ2 MACF1 CCN2 LTBP3	1.48e-05	1285	111	15	35914814
Pubmed	Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.	COL2A1 SFRP1 FBN1 AHSG LTBP2	1.54e-05	97	111	5	27559042
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	DAB2IP DIP2B ARHGAP32 ADAM9 ADGRB2 LRP1 MACF1	1.68e-05	251	111	7	27507650
Pubmed	Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse.	SFRP1 SFRP2 DLL1	1.72e-05	16	111	3	18257070
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	CCPG1 ARFGEF3 ZNF608 XPO5 MACF1	2.06e-05	103	111	5	10574462
Pubmed	SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis.	SFRP1 SFRP2 DLL1	2.08e-05	17	111	3	21478884
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL2A1 COL7A1 SSPOP FBN1 COL14A1 LTBP2	2.18e-05	175	111	6	28071719
Pubmed	Fibronectin isoforms promote postnatal skeletal development.	COL2A1 TGFBR3 FBN1	2.49e-05	18	111	3	39159790
Pubmed	Using real time RT-PCR analysis to determine multiple gene expression patterns during XX and XY mouse fetal gonad development.	COL2A1 ADAMTS19 ZFPM2 FST	2.75e-05	54	111	4	15533830
Pubmed	Tensile strain increases expression of CCN2 and COL2A1 by activating TGF-β-Smad2/3 pathway in chondrocytic cells.	COL2A1 CCN2	3.02e-05	3	111	2	23631855
Pubmed	Sodium and potassium channel dysfunctions in rare and common idiopathic epilepsy syndromes.	SCN1A KCNQ2	3.02e-05	3	111	2	19464834
Pubmed	Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family.	SFRP1 SFRP2	3.02e-05	3	111	2	9739103
Pubmed	SARPs: a family of secreted apoptosis-related proteins.	SFRP1 SFRP2	3.02e-05	3	111	2	9391078
Pubmed	DNA methylation of SFRP1, SFRP2, and WIF1 and prognosis of postoperative colorectal cancer patients.	SFRP1 SFRP2	3.02e-05	3	111	2	31830937
Pubmed	The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI.	VLDLR LRP1	3.02e-05	3	111	2	18367731
Pubmed	LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking.	LDLRAD3 LRP1	3.02e-05	3	111	2	21795536
Pubmed	LRP1 protects the vasculature by regulating levels of connective tissue growth factor and HtrA1.	LRP1 CCN2	3.02e-05	3	111	2	23868935
Pubmed	The relationship among apolipoprotein(a) polymorphisms, the low-density lipoprotein receptor-related protein, and the very low density lipoprotein receptor genes, and plasma lipoprotein(A) concentration in the Czech population.	VLDLR LRP1	3.02e-05	3	111	2	11931574
Pubmed	SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway.	SFRP1 SFRP2	3.02e-05	3	111	2	19095296
Pubmed	Methylation of SFRPs and APC genes in ovarian cancer infected with high risk human papillomavirus.	SFRP1 SFRP2	3.02e-05	3	111	2	24761891
Pubmed	Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells.	SFRP1 SFRP2	3.02e-05	3	111	2	10980594
Pubmed	The association of human fibulin-1 with elastic fibers: an immunohistological, ultrastructural, and RNA study.	FBLN1 FBN1	3.02e-05	3	111	2	7534784
Pubmed	Latent transforming growth factor beta-binding protein-3 and fibulin-1C interact with the extracellular domain of the heparin-binding EGF-like growth factor precursor.	FBLN1 LTBP3	3.02e-05	3	111	2	11846885
Pubmed	Proteolytic processing of delta-like 1 by ADAM proteases.	ADAM9 DLL1	3.02e-05	3	111	2	17107962
Pubmed	Structure-function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function.	SFRP1 SFRP2	3.02e-05	3	111	2	17471511
Pubmed	The binding sites for the very low density lipoprotein receptor and low-density lipoprotein receptor-related protein are shared within coagulation factor VIII.	VLDLR LRP1	3.02e-05	3	111	2	18277139
Pubmed	Silencing of secreted frizzled-related protein genes in MSI colorectal carcinogenesis.	SFRP1 SFRP2	3.02e-05	3	111	2	18795670
Pubmed	The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling.	FBLN1 CCN2	3.02e-05	3	111	2	9927660
Pubmed	Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.	LTBP2 LTBP3	3.02e-05	3	111	2	21700711
Pubmed	Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma.	SFRP1 SFRP2	3.02e-05	3	111	2	18497987
Pubmed	Follistatin and secreted frizzled-related protein 1, OVO homolog-like 1-regulated genes, are important for hair follicle neogenesis.	SFRP1 FST	3.02e-05	3	111	2	25827793
Pubmed	A pan-cancer analysis of secreted Frizzled-related proteins: re-examining their proposed tumour suppressive function.	SFRP1 SFRP2	3.02e-05	3	111	2	28218291
Pubmed	LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein.	FBN1 LTBP2	3.02e-05	3	111	2	17293099
Pubmed	Role of LRP1 in transport of CCN2 protein in chondrocytes.	LRP1 CCN2	3.02e-05	3	111	2	22454511
Pubmed	The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma.	SFRP1 SFRP2	3.02e-05	3	111	2	20208569
Pubmed	Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations.	TMPRSS6 TF	3.02e-05	3	111	2	21785125
Pubmed	[Methylation status of CpG islands in secreted frizzled-related protein gene promoter region of malignant hematopoietic cell lines].	SFRP1 SFRP2	3.02e-05	3	111	2	20030932
Pubmed	Latent transforming growth factor-beta binding proteins (LTBPs)--structural extracellular matrix proteins for targeting TGF-beta action.	LTBP2 LTBP3	3.02e-05	3	111	2	10743502
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	DAB2IP CACNA1E ARHGAP32 USP9X ADAM9 ADGRB2 MACF1	3.46e-05	281	111	7	28706196
Pubmed	Sfrp1 and Sfrp2 regulate anteroposterior axis elongation and somite segmentation during mouse embryogenesis.	SFRP1 SFRP2 DLL1	3.47e-05	20	111	3	16467359
Pubmed	MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.	VLDLR LRP1B LRP1	4.04e-05	21	111	3	21337463
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	DAB2IP ADGRB2 ARFGEF3 SCN1A KCNQ2 MACF1	4.23e-05	197	111	6	36604605
Pubmed	Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis.	SFRP1 SFRP2 CCN2	5.35e-05	23	111	3	26371318
Pubmed	Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer.	LRP1B ZNF608 FSHR	5.35e-05	23	111	3	20932654
Pubmed	Comparative immunolocalization of the elastin fiber-associated proteins fibrillin-1, LTBP-2, and MAGP-1 with components of the collagenous and proteoglycan matrix of the fetal human intervertebral disc.	FBN1 LTBP2	6.03e-05	4	111	2	21540769
Pubmed	Strength training with blood flow restriction diminishes myostatin gene expression.	GPRASP1 FST	6.03e-05	4	111	2	21900845
Pubmed	Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.	LTBP2 LTBP3	6.03e-05	4	111	2	15611103
Pubmed	Functions of sorting nexin 17 domains and recognition motif for P-selectin trafficking.	SELP LRP1	6.03e-05	4	111	2	15769472
Pubmed	The relationship between fertility and lifespan in humans.	FSHR FST	6.03e-05	4	111	2	21222045
Pubmed	Differential expression profiling analyses identifies downregulation of 1p, 6q, and 14q genes and overexpression of 6p histone cluster 1 genes as markers of recurrence in meningiomas.	SFRP1 CCN2	6.03e-05	4	111	2	20685720
Pubmed	Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2, and PRIMA1 in plasma samples.	SFRP1 SFRP2	6.03e-05	4	111	2	28753106
Pubmed	The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor.	VLDLR LRP1	6.03e-05	4	111	2	15863833
Pubmed	Hypermethylation and aberrant expression of secreted frizzled-related protein genes in pancreatic cancer.	SFRP1 SFRP2	6.03e-05	4	111	2	18528941
Pubmed	Models for discovery of targeted therapy in genetic epileptic encephalopathies.	SCN1A KCNQ2	6.03e-05	4	111	2	28742937
Pubmed	Extracellular fibrillar structure of latent TGF beta binding protein-1: role in TGF beta-dependent endothelial-mesenchymal transformation during endocardial cushion tissue formation in mouse embryonic heart.	LTBP2 LTBP3	6.03e-05	4	111	2	9008713
Pubmed	The latent transforming growth factor beta binding protein (LTBP) family.	LTBP2 LTBP3	6.03e-05	4	111	2	11104663
Pubmed	Common Variants and Haplotypes in the TF, TNF-α, and TMPRSS6 Genes Are Associated with Iron Status in a Female Black South African Population.	TMPRSS6 TF	6.03e-05	4	111	2	25809685
Pubmed	LDL receptor cooperates with LDL receptor-related protein in regulating plasma levels of coagulation factor VIII in vivo.	VLDLR LRP1	6.03e-05	4	111	2	15840700
Pubmed	Latent TGFβ-binding proteins regulate UCP1 expression and function via TGFβ2.	LTBP2 LTBP3	6.03e-05	4	111	2	34481123
Pubmed	Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.	SCN1A KCNQ2	6.03e-05	4	111	2	21156207
Interaction	FBXO2 interactions	THSD4 BOC SPINT1 AXL SGSH ADAM9 LRP1B TGFBR3 FBN1 AHSG COL14A1	9.93e-06	411	105	11	int:FBXO2
Cytoband	Ensembl 112 genes in cytogenetic band chr8p11	SFRP1 ADAM18 ADAM9 KAT6A NSD3	5.47e-06	103	111	5	chr8p11
Cytoband	8p11.22	ADAM18 ADAM9	5.17e-04	14	111	2	8p11.22
GeneFamily	Low density lipoprotein receptors	VLDLR LRP1B LRP1	2.23e-05	13	79	3	634
GeneFamily	Latent transforming growth factor beta binding proteins	LTBP2 LTBP3	1.12e-04	4	79	2	628
GeneFamily	Secreted frizzled-related proteins	SFRP1 SFRP2	1.87e-04	5	79	2	733
GeneFamily	ADAMTS like	THSD4 ADAMTSL2	3.90e-04	7	79	2	947
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1A EZH1 NSD3	4.36e-04	34	79	3	487
GeneFamily	Fibronectin type III domain containing	BOC COL7A1 AXL COL14A1 USH2A	6.78e-04	160	79	5	555
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	DAB2IP RASAL3	8.29e-04	10	79	2	830
GeneFamily	Collagens	COL2A1 COL7A1 COL14A1	1.06e-03	46	79	3	490
GeneFamily	Zinc fingers C2HC-type\|PHD finger proteins\|Lysine acetyltransferases	KAT6A ZFPM2	2.17e-03	16	79	2	66
GeneFamily	WAP four-disulfide core domain containing\|Fibronectin type III domain containing	WFIKKN2 SLPI	2.76e-03	18	79	2	361
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS19 ADAMTS18	3.07e-03	19	79	2	50
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM18 ADAM9	6.16e-03	27	79	2	47
Coexpression	NABA_MATRISOME	COL2A1 THSD4 ADAMTS19 COL7A1 SFRP1 SFRP2 CHRDL2 CRIM1 ADAM18 ADAM9 IL17D SSPOP SVEP1 FBLN1 FBN1 IGFBP4 OTOGL WFIKKN2 SLPI ADAMTS18 COL14A1 CCN2 LTBP2 LTBP3 FST ADAMTSL2	6.42e-14	1008	110	26	MM17056
Coexpression	NABA_MATRISOME	COL2A1 THSD4 ADAMTS19 COL7A1 SFRP1 SFRP2 CHRDL2 CRIM1 ADAM18 ADAM9 IL17D SSPOP SVEP1 FBLN1 FBN1 IGFBP4 WFIKKN2 SLPI ADAMTS18 COL14A1 CCN2 LTBP2 LTBP3 FST USH2A ADAMTSL2	9.66e-14	1026	110	26	M5889
Coexpression	NABA_CORE_MATRISOME	COL2A1 THSD4 COL7A1 CRIM1 SSPOP SVEP1 FBLN1 FBN1 IGFBP4 OTOGL COL14A1 CCN2 LTBP2 LTBP3	8.23e-12	270	110	14	MM17057
Coexpression	NABA_CORE_MATRISOME	COL2A1 THSD4 COL7A1 CRIM1 SSPOP SVEP1 FBLN1 FBN1 IGFBP4 COL14A1 CCN2 LTBP2 LTBP3 USH2A	1.05e-11	275	110	14	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	THSD4 CRIM1 SSPOP SVEP1 FBLN1 FBN1 IGFBP4 OTOGL CCN2 LTBP2 LTBP3	5.25e-10	191	110	11	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	THSD4 CRIM1 SSPOP SVEP1 FBLN1 FBN1 IGFBP4 CCN2 LTBP2 LTBP3 USH2A	6.90e-10	196	110	11	M3008
Coexpression	HAY_BONE_MARROW_STROMAL	THSD4 BOC COL7A1 SFRP1 CHRDL2 CRIM1 TF SVEP1 FBLN1 FBN1 IGFBP4 NFATC4 OTOGL SLPI COL14A1 CCN2 LTBP2 FST	3.26e-09	767	110	18	M39209
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL3	THSD4 BOC BNC2 SFRP2 CRIM1 ADAM9 ADGRB2 SSPOP LRP1B TF SCN1A LRP1 KCNN3 CCN2 LMBRD1	1.85e-08	574	110	15	M39056
Coexpression	AIZARANI_LIVER_C21_STELLATE_CELLS_1	SFRP1 FBLN1 FBN1 IGFBP4 ARID5B LRP1 COL14A1 CCN2 ADAMTSL2	1.35e-07	194	110	9	M39122
Coexpression	WANG_MLL_TARGETS	COL2A1 SFRP1 SFRP2 DLL1 APOBEC3B SVEP1 TGFBR3 NFATC4 ARID5B COL14A1	4.72e-07	294	110	10	M2456
Coexpression	WANG_MLL_TARGETS	COL2A1 SFRP1 SFRP2 DLL1 APOBEC3B SVEP1 TGFBR3 NFATC4 ARID5B COL14A1	6.80e-07	306	110	10	MM1076
Coexpression	ESC_J1_UP_LATE.V1_UP	COL2A1 CRIM1 TGFBR3 IGFBP4 P2RX4 CCN2 FST LMBRD1	1.22e-06	186	110	8	M2768
Coexpression	BOQUEST_STEM_CELL_UP	AXL LRP1B SVEP1 FBLN1 FBN1 LRP1 COL14A1 LTBP2 FST	1.62e-06	261	110	9	M1834
Coexpression	HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	COL7A1 SFRP1 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 CCN2	2.10e-06	200	110	8	M5930
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_MID_BASAL_CELL	THSD4 BOC COL7A1 FBN1 IGFBP4 SLPI COL14A1	3.25e-06	149	110	7	M45703
Coexpression	GAO_LARGE_INTESTINE_24W_C1_DCLK1POS_PROGENITOR	BOC SFRP1 SFRP2 SVEP1 FBLN1 COL14A1	3.89e-06	99	110	6	M39152
Coexpression	NIKOLSKY_BREAST_CANCER_8P12_P11_AMPLICON	SFRP1 ADAM18 ADAM9 KAT6A NSD3	4.18e-06	57	110	5	M8293
Coexpression	NABA_MATRISOME_HIGHLY_METASTATIC_BREAST_CANCER_TUMOR_CELL_DERIVED	ADAM9 IGFBP4 CCN2 LTBP3	6.43e-06	29	110	4	M47987
Coexpression	CHICAS_RB1_TARGETS_GROWING	THSD4 BNC2 AXL TTK APOBEC3B TSPAN5 FBLN1 LTBP2	8.57e-06	242	110	8	M2128
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN	DAB2IP ADAMTS19 GPRASP1 ADGRB2 CD83 FBLN1 IGFBP4 WFIKKN2 ARID5B ADAMTS18	9.37e-06	411	110	10	M1351
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN	DAB2IP ADAMTS19 GPRASP1 ADGRB2 CD83 FBLN1 IGFBP4 WFIKKN2 ARID5B ADAMTS18	1.04e-05	416	110	10	MM1002
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_MID_MESOTHELIAL_CELL	COL2A1 THSD4 BNC2 VPS18 CCPG1 CRIM1 AXL USP9X SGSH ADGRB2 ZFPM2 PIM3 KLHL36 SLPI LTBP2	1.10e-05	955	110	15	M45680
Coexpression	PETRETTO_CARDIAC_HYPERTROPHY	CRIM1 FBN1 ARID5B LTBP3	1.24e-05	34	110	4	M14043
Coexpression	GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_DN	PLEKHB2 DIP2B ADAM9 LDLRAD3 IGFBP4 FMN1 ARID5B	2.08e-05	198	110	7	M7229
Coexpression	GSE14350_IL2RB_KO_VS_WT_TREG_DN	SELP AXL CD83 TF APOBEC3B ZNF608 CCN2	2.22e-05	200	110	7	M3422
Coexpression	GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_DN	PLEKHB2 SELP SFRP1 AXL CD83 SLPI CCN2	2.22e-05	200	110	7	M3904
Coexpression	GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_UP	SFRP1 AXL ESRP1 CD83 P2RX4 WFIKKN2 LRP1	2.22e-05	200	110	7	M6200
Coexpression	DESCARTES_FETAL_THYMUS_STROMAL_CELLS	SFRP1 SFRP2 FBLN1 FBN1 LRP1 COL14A1	2.51e-05	137	110	6	M40313
Coexpression	NABA_MATRISOME_HIGHLY_METASTATIC_BREAST_CANCER	ADAM9 IGFBP4 CCN2 LTBP3	2.64e-05	41	110	4	M47988
Coexpression	LAKE_ADULT_KIDNEY_C29_UNKNOWN_NOVEL_PT_CFH_POS_SUBPOPULATION_S2	BNC2 CRIM1 ZFPM2 MACF1 CCN2	3.16e-05	86	110	5	M39248
Coexpression	LIM_MAMMARY_STEM_CELL_UP	COL7A1 AXL DLL1 SVEP1 TGFBR3 IGFBP4 LRP1 COL14A1 CCN2 FST	3.47e-05	479	110	10	M2573
Coexpression	TRAVAGLINI_LUNG_ADVENTITIAL_FIBROBLAST_CELL	SFRP1 SFRP2 SVEP1 FBLN1 FBN1 IGFBP4 SLPI LRP1	3.64e-05	296	110	8	M41675
Coexpression	JONES_OVARY_NK_CELL	BNC2 CRIM1 FBN1 COL14A1 CCN2	3.73e-05	89	110	5	M48353
Coexpression	LIM_MAMMARY_STEM_CELL_UP	COL7A1 AXL DLL1 SVEP1 TGFBR3 IGFBP4 LRP1 COL14A1 CCN2 FST	3.73e-05	483	110	10	MM1082
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2A	THSD4 BOC SFRP1 SFRP2 ADGRB2 TF SCN1A LRP1 KCNN3 KCNQ2 CCN2	4.54e-05	600	110	11	M39055
Coexpression	CUI_DEVELOPING_HEART_SMOOTH_MUSCLE_CELL	SFRP2 FBLN1 IGFBP4 COL14A1	4.96e-05	48	110	4	M39318
Coexpression	DESCARTES_FETAL_LIVER_MESOTHELIAL_CELLS	THSD4 BOC BNC2 SPINT1 ADGRB2 ARFGEF3 CRACDL SLPI	5.39e-05	313	110	8	M40228
Coexpression	GAO_LARGE_INTESTINE_ADULT_CJ_IMMUNE_CELLS	SFRP1 AXL TGFBR3 FBLN1 FBN1 NFATC4 LRP1 COL14A1 LTBP2 FST	5.41e-05	505	110	10	M39167
Coexpression	SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION	VLDLR FBN1 CCN2 LTBP2	5.83e-05	50	110	4	M1259
Coexpression	CUI_TCF21_TARGETS_2_DN	CCPG1 CRIM1 USP9X ADAM9 TSPAN5 ZFX ARFGEF3 TGFBR3 P2RX4 ARID5B MACF1 CCN2 LMBRD1	6.13e-05	854	110	13	M1533
Coexpression	NABA_MATRISOME_ASSOCIATED	ADAMTS19 SFRP1 SFRP2 CHRDL2 ADAM18 ADAM9 IL17D WFIKKN2 SLPI ADAMTS18 FST ADAMTSL2	6.42e-05	738	110	12	MM17058
Coexpression	TABULA_MURIS_SENIS_MAMMARY_GLAND_BASAL_CELL_AGEING	BOC SFRP1 TF PIM3 SLPI ARID5B LRP1 LTBP3	6.58e-05	322	110	8	MM3786
Coexpression	SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION	VLDLR FBN1 CCN2 LTBP2	6.81e-05	52	110	4	MM1118
Coexpression	KANG_IMMORTALIZED_BY_TERT_DN	TSPAN5 ZFPM2 ZFX TGFBR3 FSHR	6.83e-05	101	110	5	M1514
Coexpression	BROWNE_HCMV_INFECTION_20HR_DN	AXL TGFBR3 MACF1 CCN2 FST	7.16e-05	102	110	5	M5601
Coexpression	NABA_MATRISOME_ASSOCIATED	ADAMTS19 SFRP1 SFRP2 CHRDL2 ADAM18 ADAM9 IL17D WFIKKN2 SLPI ADAMTS18 FST ADAMTSL2	7.58e-05	751	110	12	M5885
Coexpression	IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN	SFRP2 FBLN1 FBN1 SLPI LTBP2	8.99e-05	107	110	5	M4913
Coexpression	CUI_TCF21_TARGETS_2_DN	CCPG1 CRIM1 USP9X ADAM9 TSPAN5 ZFX ARFGEF3 TGFBR3 P2RX4 ARID5B MACF1 CCN2 LMBRD1	9.08e-05	888	110	13	MM1018
Coexpression	ONDER_CDH1_TARGETS_2_UP	TGFBR3 FBLN1 FBN1 IGFBP4 ARID5B CCN2 LTBP2	1.08e-04	257	110	7	M13867
Coexpression	WU_CELL_MIGRATION	SPINT1 AXL ESRP1 FBLN1 SLPI ARID5B	1.25e-04	183	110	6	M2001
Coexpression	HE_LIM_SUN_FETAL_LUNG_C3_OMD_POS_ENDOTHELIAL_CELL	SELP CRIM1 LDLRAD3 NPIPA7 NPIPA8 FBLN1 CCN2 LTBP2	1.29e-04	355	110	8	M45758
Coexpression	CUI_DEVELOPING_HEART_C3_FIBROBLAST_LIKE_CELL	FBLN1 FBN1 LRP1 COL14A1 CCN2	1.37e-04	117	110	5	M39300
Coexpression	HEVNER_CORTEX_COMMITTED_TO_CORTICOTHALAMIC_PROJECTION_NEURON_FATE	CACNA1E ZFPM2 ADAMTS18	1.55e-04	25	110	3	MM424
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HOPC	COL2A1 BOC TTK SSPOP TF SCN1A LRP1 KCNQ2	1.59e-04	366	110	8	M39052
Coexpression	RIGGI_EWING_SARCOMA_PROGENITOR_DN	BNC2 SVEP1 TGFBR3 FBLN1 COL14A1 FST	1.82e-04	196	110	6	M13256
Coexpression	INGRAM_SHH_TARGETS_UP	TSPAN5 AKAP4 FBN1 IGFBP4 CCN2	1.87e-04	125	110	5	M1320
Coexpression	GSE45365_NK_CELL_VS_CD11B_DC_UP	COL2A1 ZSCAN12 TMPRSS6 LRP1B MOV10L1 AHSG	1.98e-04	199	110	6	M10030
Coexpression	GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP	CD83 FAAP100 ARFGEF3 ZNF608 LRP1 LMBRD1	1.98e-04	199	110	6	M9853
Coexpression	GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_DN	DAB2IP SGSH RASAL3 CRACDL COL14A1 LTBP3	2.03e-04	200	110	6	M6258
Coexpression	GSE11961_UNSTIM_VS_ANTI_IGM_AND_CD40_STIM_6H_FOLLICULAR_BCELL_DN	GPRASP1 ARHGAP32 ZSCAN12 TSPAN5 SLPI ARID5B	2.03e-04	200	110	6	M9335
Coexpression	GSE27786_CD8_TCELL_VS_ERYTHROBLAST_UP	SGSH ADAM9 TSPAN5 PIM3 P2RX4 LMBRD1	2.03e-04	200	110	6	M4841
Coexpression	GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY7_DN	COL2A1 DENND3 AKAP4 SLPI LRP1 AHSG	2.03e-04	200	110	6	M6585
Coexpression	GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP	CRIM1 NSD3 TGFBR3 TRANK1 ARID5B KLRD1	2.03e-04	200	110	6	M6514
Coexpression	GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP	PLEKHB2 GPRASP1 KAT6A P2RX4 MACF1 LTBP3	2.03e-04	200	110	6	M9889
Coexpression	GSE19825_NAIVE_VS_IL2RALOW_DAY3_EFF_CD8_TCELL_UP	GPRASP1 SVEP1 ZFPM2 ZFX TGFBR3 FBLN1	2.03e-04	200	110	6	M4297
Coexpression	GSE29164_DAY3_VS_DAY7_CD8_TCELL_TREATED_MELANOMA_UP	SPINT1 APOBEC3B SVEP1 AHSG COL14A1 ZNF445	2.03e-04	200	110	6	M8488
Coexpression	GSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	CCPG1 AFF3 P2RX4 ARID5B ARHGAP45 ZNF445	2.03e-04	200	110	6	M9136
Coexpression	CHEN_METABOLIC_SYNDROM_NETWORK	PLEKHB2 SYBU CD83 APOBEC3B SVEP1 FBN1 P2RX4 FMN1 ZDHHC6 FSHR SLPI COL14A1 LTBP2 LTBP3 ARHGAP45	2.15e-04	1242	110	15	M1920
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	GPRASP1 CACNA1E DIP2B CCPG1 CRIM1 AFF3 FAM117B SYBU SSPOP LRP1B ZFPM2 ARFGEF3 SCN1A KCNN3	2.20e-04	1106	110	14	M39071
Coexpression	RUBENSTEIN_SKELETAL_MUSCLE_FBN1_FAP_CELLS	AXL TGFBR3 FBLN1 FBN1 SLPI LRP1 COL14A1	2.23e-04	289	110	7	M41750
Coexpression	WONG_ADULT_TISSUE_STEM_MODULE	DAB2IP SELP VLDLR ARHGAP32 SFRP1 CRIM1 P2RX4 MACF1 CCN2 LTBP2 LTBP3	2.28e-04	721	110	11	M1999
Coexpression	NABA_MATRISOME_METASTATIC_LUNG_LYMPH_NODE_METASTASIS	COL2A1 COL14A1 LTBP2	2.43e-04	29	110	3	MM17055
Coexpression	MIKKELSEN_MEF_ICP_WITH_H3K27ME3	THSD4 ESRP1 SYBU SCN1A AHSG KCNN3	2.44e-04	207	110	6	M1963
Coexpression	OHM_EMBRYONIC_CARCINOMA_UP	SFRP1 SFRP2	2.59e-04	6	110	2	M6244
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	ADAMTS19 CRIM1 TGFBR3 ZDHHC6 MACF1 CCN2	2.78e-04	212	110	6	M39221
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HPROGBP	COL2A1 BOC SFRP1 SFRP2 TTK KCNQ2 CCN2	2.79e-04	300	110	7	M39059
Coexpression	HALLMARK_COAGULATION	ADAM9 TMPRSS6 TF FBN1 LRP1	2.96e-04	138	110	5	M5946
Coexpression	CARD_MIR302A_TARGETS	VLDLR KAT6A DLL1 ZFPM2	3.14e-04	77	110	4	M2208
Coexpression	REN_ALVEOLAR_RHABDOMYOSARCOMA_DN	PLEKHB2 CCPG1 AXL ADAM9 FTSJ1 FBN1 LRP1 CCN2	3.26e-04	407	110	8	M19541
Coexpression	MEL18_DN.V1_UP	VLDLR COL7A1 CD83 TGFBR3 KCNN3	3.26e-04	141	110	5	M2784
Coexpression	RIGGINS_TAMOXIFEN_RESISTANCE_DN	ADAM9 SYBU TSPAN5 SCN1A ARID5B LTBP3	3.47e-04	221	110	6	M15835
Coexpression	AIZARANI_LIVER_C29_MVECS_2	SELP CRIM1 TGFBR3 IGFBP4 ARID5B KCNN3 CCN2	3.61e-04	313	110	7	M39128
Coexpression	MIKKELSEN_MEF_ICP_WITH_H3K27ME3	THSD4 ESRP1 SYBU SCN1A AHSG KCNN3	3.64e-04	223	110	6	MM838
Coexpression	LI_INDUCED_T_TO_NATURAL_KILLER_UP	TF DENND3 ARFGEF3 PIM3 ZNF608 CCN2 KLRD1	3.89e-04	317	110	7	M2086
Coexpression	CHEN_METABOLIC_SYNDROM_NETWORK	PLEKHB2 SYBU CD83 APOBEC3B SVEP1 FBN1 P2RX4 FMN1 ZDHHC6 FSHR SLPI COL14A1 LTBP2 LTBP3 ARHGAP45	3.98e-04	1316	110	15	MM1052
Coexpression	DURANTE_ADULT_OLFACTORY_NEUROEPITHELIUM_FIBROBLASTS_STROMAL_CELLS	SFRP1 SFRP2 FBLN1 IGFBP4	3.99e-04	82	110	4	M39274
Coexpression	NABA_MATRISOME_PRIMARY_METASTATIC_LUNG_TUMOR	COL2A1 COL14A1 LTBP2	4.27e-04	35	110	3	MM17054
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HPROGFPL	COL2A1 SFRP2 TTK FBLN1 FBN1 KCNQ2 CCN2	4.27e-04	322	110	7	M39060
Coexpression	ONDER_CDH1_SIGNALING_VIA_CTNNB1	SYBU CD83 FBN1 LTBP2	4.38e-04	84	110	4	M15484
Coexpression	HE_LIM_SUN_FETAL_LUNG_C3_VENOUS_ENDOTHELIAL_CELL	SELP DLL1 FBN1 LTBP3	4.58e-04	85	110	4	M45761
Coexpression	DELYS_THYROID_CANCER_DN	SFRP1 SSPOP LRP1B ZFPM2 TGFBR3 FBLN1	4.59e-04	233	110	6	M13273
Coexpression	GOZGIT_ESR1_TARGETS_DN	THSD4 ADAMTS19 VLDLR CCPG1 AFF3 ARFGEF3 TRANK1 IGFBP4 ARID5B MACF1 LTBP2	4.74e-04	786	110	11	M10961
Coexpression	KIM_GLIS2_TARGETS_UP	FBN1 COL14A1 CCN2 LTBP2	4.79e-04	86	110	4	M2259
Coexpression	MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_9	KAT6A NSD3	4.81e-04	8	110	2	M9239
Coexpression	GROSS_HYPOXIA_VIA_ELK3_DN	VLDLR PIM3 SLPI CCN2 FST	5.04e-04	155	110	5	M1304
Coexpression	NABA_ECM_REGULATORS	ADAMTS19 ADAM18 ADAM9 SLPI ADAMTS18 ADAMTSL2	5.13e-04	238	110	6	M3468
Coexpression	JONES_OVARY_STROMAL	BNC2 FBLN1 FBN1 IGFBP4 COL14A1	5.19e-04	156	110	5	M48352
Coexpression	INGRAM_SHH_TARGETS_UP	TSPAN5 AKAP4 FBN1 IGFBP4 CCN2	5.19e-04	156	110	5	MM550
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2B	BOC SFRP2 ADGRB2 TF SCN1A LRP1 KCNN3 KCNQ2	5.37e-04	439	110	8	M39054
Coexpression	DURANTE_ADULT_OLFACTORY_NEUROEPITHELIUM_MONOCYTES	SFRP1 SFRP2 CD83	5.45e-04	38	110	3	M39297
CoexpressionAtlas	kidney_adult_RenalCapsule_top-relative-expression-ranked_1000	PLEKHB2 BOC VLDLR BNC2 SFRP1 SFRP2 CRIM1 TF SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 FMN1 SLPI LRP1 COL14A1 LTBP2 LTBP3 FST	1.25e-09	778	105	20	gudmap_kidney_adult_RenalCapsule_1000
CoexpressionAtlas	kidney_adult_RenalCapsule_k-means-cluster#2_top-relative-expression-ranked_1000	BOC BNC2 SFRP1 TF SVEP1 ZFPM2 FBLN1 FBN1 SLPI LRP1 COL14A1 LTBP2 LTBP3 FST	3.93e-09	369	105	14	gudmap_kidney_adult_RenalCapsule_k2_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_500	BOC ADAMTS19 BNC2 SFRP1 AXL AFF3 TSPAN5 ZFPM2 FBN1 TRANK1 LRP1 FST	4.95e-07	388	105	12	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_500
CoexpressionAtlas	Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5	BOC BNC2 SFRP1 AXL TF SVEP1 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 LTBP3	5.17e-07	466	105	13	GSM777050_500
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000	BOC ADAMTS19 BNC2 SFRP1 AXL USP9X AFF3 APOBEC3B TSPAN5 SVEP1 ZFPM2 FBN1 TRANK1 LRP1 COL14A1 FST	7.01e-07	740	105	16	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlas	Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4	BOC SFRP1 SFRP2 AXL SVEP1 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 FST	1.72e-06	437	105	12	GSM777046_500
CoexpressionAtlas	Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4	BNC2 SFRP2 AXL TF SVEP1 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 LTBP2	2.61e-06	455	105	12	GSM777055_500
CoexpressionAtlas	kidney_adult_RenalCapsule_top-relative-expression-ranked_500	BOC VLDLR SFRP1 CRIM1 TF SVEP1 FBN1 SLPI LRP1 COL14A1 FST	5.69e-06	408	105	11	gudmap_kidney_adult_RenalCapsule_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	BOC ADAMTS19 BNC2 SFRP1 AXL AFF3 TSPAN5 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 TRANK1 LRP1 COL14A1	6.03e-06	773	105	15	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	COL2A1 BOC COL7A1 CCPG1 SFRP2 AXL SGSH ADAM9 KAT6A PCDHB2 EZH1 DLL1 TGFBR3 FBN1 P2RX4 ZNF608 NFATC4 SIK2 CCN2 LTBP2 FST	8.49e-06	1466	105	21	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500	BNC2 SFRP1 AFF3 SVEP1 ZFPM2 TGFBR3 FBN1 TRANK1 LRP1 COL14A1	1.09e-05	356	105	10	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500	BNC2 SFRP1 AXL AFF3 ZFPM2 TGFBR3 FBN1 TRANK1 LRP1 COL14A1	1.32e-05	364	105	10	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	BNC2 SFRP1 SFRP2 AXL AFF3 TTK TSPAN5 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 TRANK1 LRP1 COL14A1	1.35e-05	827	105	15	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000	BOC VLDLR BNC2 SFRP1 SFRP2 AXL AFF3 SVEP1 ZFPM2 TGFBR3 FBN1 LRP1 ADAMTS18 COL14A1 FST	1.42e-05	831	105	15	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlas	Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2	SFRP2 CRIM1 AXL SVEP1 TGFBR3 FBN1 IGFBP4 LRP1 COL14A1 CCN2 FST	1.52e-05	453	105	11	GSM777067_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500	BNC2 SFRP1 AXL AFF3 ZFPM2 TGFBR3 FBN1 TRANK1 LRP1 COL14A1	1.63e-05	373	105	10	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3	COL2A1 BOC CRIM1 TMPRSS6 AFF3 SSPOP LRP1B TF SVEP1 ZFPM2 TGFBR3 FBN1 FSHR ARID5B AHSG ADAMTS18 LTBP2	2.52e-05	1094	105	17	ratio_EB_vs_SC_2500_K3
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	BOC BNC2 SFRP1 AXL AFF3 TSPAN5 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 TRANK1 LRP1 COL14A1	2.54e-05	768	105	14	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	kidney_adult_RenalCapsule_k-means-cluster#1_top-relative-expression-ranked_500	BOC SFRP1 TF SVEP1 FBN1 SLPI COL14A1 FST	2.57e-05	240	105	8	gudmap_kidney_adult_RenalCapsule_k1_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000	COL2A1 BNC2 COL7A1 SFRP2 SPINT1 AXL ESRP1 ADGRB2 IL17D DLL1 WFIKKN2 ARID5B MACF1 COL14A1 LTBP3 KDF1	2.60e-05	984	105	16	Facebase_RNAseq_e10.5_Olfactory Pit_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	BOC ADAMTS19 BNC2 SFRP1 AXL AFF3 TTK SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 LRP1 COL14A1	2.88e-05	777	105	14	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000	BOC ADAMTS19 BNC2 SFRP1 AXL AFF3 TSPAN5 ZFPM2 FBN1 TRANK1 IGFBP4 P2RX4 LRP1 FST	3.14e-05	783	105	14	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_500	SETD1A VLDLR BNC2 SFRP1 AFF3 NSD3 ARID5B COL14A1 LTBP2 ZNF445	3.22e-05	404	105	10	gudmap_developingGonad_e18.5_epididymis_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	BOC BNC2 SFRP1 AXL AFF3 TTK TSPAN5 SVEP1 ZFPM2 TGFBR3 FBN1 TRANK1 LRP1 COL14A1	3.60e-05	793	105	14	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000	BOC ADAMTS19 BNC2 SFRP1 AXL AFF3 APOBEC3B TSPAN5 ZFPM2 FBLN1 FBN1 TRANK1 LRP1 FST	3.80e-05	797	105	14	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500	BNC2 SFRP1 AXL AFF3 TSPAN5 SVEP1 ZFPM2 FBN1 LRP1 COL14A1	4.29e-05	418	105	10	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000	BOC VLDLR BNC2 SFRP1 SVEP1 TGFBR3 FBN1 LRP1 ADAMTS18	6.62e-05	354	105	9	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlas	gudmap_RNAseq_p2_CD2APMEISWT_2500_K4	PLEKHB2 SFRP2 CRIM1 AXL SGSH ADAM9 TF TGFBR3 FBN1 P2RX4 ARID5B LRP1 CCN2 LTBP3	6.87e-05	842	105	14	gudmap_RNAseq_p2_CD2APMEISWT_2500_K4
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_500	BOC ADAMTS19 BNC2 SFRP1 ZFPM2 FBN1 TRANK1 LRP1 FST	7.06e-05	357	105	9	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_500
CoexpressionAtlas	Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5	SVEP1 FBN1 IGFBP4 LRP1 COL14A1	7.19e-05	87	105	5	GSM777050_100
CoexpressionAtlas	EB bone marrow_vs_EB blastocyst-Confounder_removed-fold2.0_adjp0.05	VLDLR SPINT1 CD83 TF TSPAN5 ZFPM2 TGFBR3 TRANK1 SLPI AHSG	7.36e-05	446	105	10	PCBC_ratio_EB bone marrow_vs_EB blastocyst_cfr-2X-p05
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_1000	BOC BNC2 SFRP1 AXL AFF3 TSPAN5 SVEP1 ZFPM2 FBLN1 FBN1 ARID5B LRP1 CCN2 FST	8.40e-05	858	105	14	gudmap_dev gonad_e11.5_F_GonMes_Sma_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_500	BOC BNC2 SFRP1 TSPAN5 FBN1 LRP1	8.77e-05	146	105	6	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_500
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_reference_CardiacMyocyte_top-relative-expression-ranked_1000	THSD4 CRIM1 AXL ADAM9 SVEP1 TGFBR3 FBN1 IGFBP4 MOV10L1 LRP1 ADAMTS18 COL14A1 CCN2 LTBP2 FST	8.88e-05	975	105	15	PCBC_ctl_CardiacMyocyte_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000	COL2A1 BNC2 COL7A1 SFRP2 AXL ADGRB2 IL17D RASAL3 FMN1 WFIKKN2 MOV10L1 ARID5B MACF1 COL14A1 LTBP3	9.19e-05	978	105	15	Facebase_RNAseq_e10.5_Mandibular Arch_1000
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_reference_BronchSmoothMuscl_top-relative-expression-ranked_1000	SFRP1 AXL APOBEC3B TSPAN5 SVEP1 TGFBR3 FBN1 IGFBP4 NFATC4 FMN1 ARID5B LRP1 COL14A1 LTBP2 FST	9.51e-05	981	105	15	PCBC_ctl_BronchSmoothMuscl_1000
CoexpressionAtlas	kidney_adult_Mesangium_Meis_top-relative-expression-ranked_1000	VLDLR SFRP2 CRIM1 AXL ADAM9 TF TGFBR3 FBN1 IGFBP4 P2RX4 ARID5B LRP1 CCN2 LMBRD1	9.96e-05	872	105	14	gudmap_kidney_adult_Mesangium_Meis_1000
CoexpressionAtlas	JC_fibro_top-relative-expression-ranked_1000_k-means-cluster#1	CRIM1 SVEP1 FBN1 IGFBP4 FMN1 MOV10L1 ARID5B LRP1 CCN2 LTBP2	1.02e-04	464	105	10	JC_fibro_1000_K1
CoexpressionAtlas	JC_fibro_top-relative-expression-ranked_1000	COL7A1 CCPG1 CRIM1 AFF3 SVEP1 FBLN1 FBN1 TRANK1 IGFBP4 FMN1 MOV10L1 ARID5B LRP1 CCN2 LTBP2	1.05e-04	990	105	15	JC_fibro_1000
CoexpressionAtlas	Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4	SFRP2 AXL FBN1 LRP1 COL14A1	1.21e-04	97	105	5	GSM777046_100
CoexpressionAtlas	dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_500	BOC BNC2 SFRP1 AFF3 TSPAN5 ZFPM2 FBN1 LRP1 FST	1.25e-04	385	105	9	gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_500
CoexpressionAtlas	Mesoderm Day 15-method_episomal_vs_Mesoderm Day 15-method_NA-Confounder_removed-fold2.0_adjp0.05	COL2A1 SFRP2 TF ADAMTS18 FST	1.39e-04	100	105	5	PCBC_ratio_MESO-15_from-episomal_vs_MESO-15_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 15-reprogram_OSK-L-l-p53KD_vs_Mesoderm Day 15-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	COL2A1 SFRP2 TF ADAMTS18 FST	1.39e-04	100	105	5	PCBC_ratio_MESO-15_from-OSK-L-l-p53KD_vs_MESO-15_from-ESC_cfr-2X-p05
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#3_top-relative-expression-ranked_100	VLDLR USP9X ZFX	1.69e-04	22	105	3	gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_100_k3
CoexpressionAtlas	Myeloid Cells, MF.RP.Sp, F4/80hi CD11blo CD11c- autofluorescent, Spleen, avg-3	ARHGAP32 AXL CD83 TF P2RX4 FMN1 SLPI LRP1 COL14A1	1.76e-04	403	105	9	GSM605853_500
CoexpressionAtlas	kidney_adult_Podocyte_MafB_k-means-cluster#1_top-relative-expression-ranked_500	CRIM1 TGFBR3 P2RX4 CCN2 LMBRD1	2.18e-04	110	105	5	gudmap_kidney_adult_Podocyte_MafB_k1_500
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_1000	BOC BNC2 SFRP1 TSPAN5 SVEP1 FBLN1 FBN1 LRP1	2.22e-04	327	105	8	gudmap_dev gonad_e11.5_F_GonMes_Sma_k4_1000
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	COL2A1 BOC COL7A1 SFRP2 AXL ADAM9 KAT6A PCDHB2 EZH1 DLL1 TSPAN5 TGFBR3 FBN1 NFATC4 LTBP2	2.58e-04	1075	105	15	PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlas	dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_1000	SPINT1 ESRP1 TF FBN1	2.69e-04	63	105	4	gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k2_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000	BNC2 SFRP1 TSPAN5 SVEP1 TGFBR3 FBLN1 FBN1 LRP1	2.72e-04	337	105	8	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_1000	VLDLR SFRP1 AFF3 SVEP1 ARID5B LRP1 ZNF445	2.84e-04	256	105	7	gudmap_developingGonad_e14.5_ epididymis_1000_k4
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05	COL2A1 BOC COL7A1 SFRP2 AXL KAT6A PCDHB2 EZH1 DLL1 TSPAN5 FBN1 NFATC4 CCN2 LTBP2	2.90e-04	967	105	14	PCBC_ratio_ECTO_vs_MESO-5_cfr-2X-p05
CoexpressionAtlas	FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000	BNC2 SFRP2 SPINT1 AXL ESRP1 ADGRB2 IL17D DLL1 WFIKKN2 ARID5B COL14A1 CCN2 LTBP3 KDF1	3.09e-04	973	105	14	Facebase_RNAseq_e9.5_Olfactory Placode_1000
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000	BNC2 SFRP1 SFRP2 AXL ADGRB2 DLL1 FBN1 FMN1 WFIKKN2 ARID5B COL14A1 LTBP2 LTBP3 ADAMTSL2	3.09e-04	973	105	14	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	COL2A1 BOC BNC2 TTK FBN1 RASAL3 NFATC4 FMN1 WFIKKN2 ARID5B MACF1 ADAMTSL2	3.10e-04	744	105	12	Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K4
CoexpressionAtlas	BM Top 100 - cervix	SFRP1 FBLN1 SLPI COL14A1	3.21e-04	66	105	4	BM Top 100 - cervix
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500	BOC BNC2 SFRP1 FBN1 LRP1	3.52e-04	122	105	5	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000	COL2A1 SFRP2 CHRDL2 AFF3 DLL1 LRP1B TF SVEP1 FSHR SLPI AHSG ADAMTS18 KCNQ2 COL14A1	3.53e-04	986	105	14	PCBC_EB_fibroblast_1000
CoexpressionAtlas	ECTO blastocyst_vs_ECTO cord blood-Confounder_removed-fold2.0_adjp0.05	SFRP1 SFRP2 ESRP1 DLL1 FBLN1 LTBP2	3.56e-04	189	105	6	PCBC_ratio_ECTO blastocyst_vs_ECTO cord blood_cfr-2X-p05
CoexpressionAtlas	B cells, B.Fo.PC, IgD+ IgM+ CD19+ CD43- CD5- CD23+, Peritoneal Cavity, avg-3	CACNA1E AFF3 CD83 APOBEC3B DENND3 ZNF608 MACF1 LMBRD1	3.64e-04	352	105	8	GSM538198_500
CoexpressionAtlas	Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3	AXL ADAM9 SVEP1 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1	3.66e-04	445	105	9	GSM777043_500
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_EmbryoidBody_top-relative-expression-ranked_1000	COL2A1 BOC ADAMTS19 SFRP2 CHRDL2 AFF3 LRP1B TF SVEP1 SLPI AHSG ADAMTS18 KCNQ2 COL14A1	3.83e-04	994	105	14	PCBC_EB_1000
CoexpressionAtlas	kidney_adult_RenCorpuscGlomer_top-relative-expression-ranked_1000	PLEKHB2 ARHGAP32 SFRP2 CRIM1 ADAM9 FAM117B TSPAN5 DENND3 TGFBR3 P2RX4 ARID5B CCN2 LMBRD1	3.92e-04	878	105	13	gudmap_kidney_adult_RenCorpuscGlomer_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	BOC ADAMTS19 AFF3 TSPAN5 ZFPM2	3.94e-04	125	105	5	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k1_1000
CoexpressionAtlas	ovary	VLDLR BNC2 ZFPM2 WFIKKN2 FSHR	3.94e-04	125	105	5	ovary
CoexpressionAtlas	BM Top 100 - ovary	BNC2 TGFBR3 IGFBP4 COL14A1	4.03e-04	70	105	4	BM Top 100 - ovary
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500	BNC2 SFRP1 AFF3 SVEP1 ZFPM2 FBN1 LRP1 COL14A1	4.30e-04	361	105	8	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#5_top-relative-expression-ranked_1000	VLDLR SFRP1 AFF3 SVEP1 LRP1 COL14A1	4.44e-04	197	105	6	gudmap_developingGonad_e16.5_epididymis_1000_k5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#5	COL2A1 BNC2 ADGRB2 WFIKKN2 ARID5B MACF1 LTBP3	4.47e-04	276	105	7	Facebase_RNAseq_e10.5_Olfactory Pit_1000_K5
CoexpressionAtlas	facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4	COL2A1 THSD4 BOC SFRP1 AFF3 ADGRB2 TF SVEP1 ZFPM2 FBN1 RASAL3 NFATC4 SLPI ADAMTS18 LTBP3	5.16e-04	1148	105	15	facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_500	BOC ADAMTS19 BNC2 SFRP1 ZFPM2 FBN1 LRP1 FST	5.24e-04	372	105	8	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_500
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	DAB2IP SETD1A VLDLR BNC2 SFRP1 AFF3 SVEP1 NSD3 ARID5B LRP1 COL14A1 ZNF445	5.31e-04	790	105	12	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	JC_fibro_top-relative-expression-ranked_500_k-means-cluster#3	CRIM1 AFF3 SVEP1 FBN1 IGFBP4 CCN2	5.62e-04	206	105	6	JC_fibro_500_K3
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000	SETD1A VLDLR BNC2 SFRP1 CRIM1 AFF3 ARID5B LRP1 COL14A1 LTBP2 LTBP3 ZNF445	5.74e-04	797	105	12	gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500	BNC2 SFRP1 TSPAN5 SVEP1 FBN1 LRP1	5.77e-04	207	105	6	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	SETD1A VLDLR BNC2 SFRP1 CRIM1 AFF3 NSD3 ARID5B LRP1 COL14A1 LTBP2 ZNF445	5.87e-04	799	105	12	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_200	ADAMTS19 SFRP1 ZFPM2 TRANK1 FST	5.98e-04	137	105	5	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_200
CoexpressionAtlas	Myeloid Cells, MF.RP.Sp, F4/80hi CD11blo CD11c- autofluorescent, Spleen, avg-3	AXL TF LRP1 COL14A1	6.08e-04	78	105	4	GSM605853_100
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000	BOC ADAMTS19 GPRASP1 BNC2 USP9X AFF3 APOBEC3B TSPAN5 ZFPM2 TRANK1 P2RX4 FST	6.13e-04	803	105	12	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_1000
CoexpressionAtlas	CD positive, CD4 Control, 4+ 8- B220-, Spleen, avg-4	CRIM1 AFF3 TGFBR3 RASAL3 IGFBP4 MACF1	6.22e-04	210	105	6	GSM403995_500
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#1_top-relative-expression-ranked_100	VLDLR AFM	6.65e-04	8	105	2	gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_100_k1
CoexpressionAtlas	gamma delta T cells, Tgd.Sp, TCRd+ CD3e+, Spleen, avg-3	AXL TF COL14A1 KLRD1	7.01e-04	81	105	4	GSM476672_100
CoexpressionAtlas	FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500	BNC2 COL7A1 SFRP2 AXL ADGRB2 WFIKKN2 ARID5B COL14A1 LTBP3	7.20e-04	489	105	9	Facebase_RNAseq_e8.5_Paraxial Mesoderm_500
CoexpressionAtlas	EB blastocyst_vs_EB amniotic fluid MSC-Confounder_removed-fold2.0_adjp0.05	SFRP1 TF SVEP1 TGFBR3 AHSG COL14A1 FST	7.32e-04	300	105	7	PCBC_ratio_EB blastocyst_vs_EB amniotic fluid MSC_cfr-2X-p05
CoexpressionAtlas	gamma delta T cells, Tgd.Sp, TCRd+ CD3e+, Spleen, avg-3	CRIM1 AXL TF IGFBP4 SLPI LRP1 COL14A1 KLRD1	7.50e-04	393	105	8	GSM476672_500
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_100	VLDLR USP9X ZFX AFM	7.69e-04	83	105	4	gudmap_developingKidney_e15.5_ureter tip_100_flank cortic collct
CoexpressionAtlas	Myeloid Cells, MF.Lu, CD11chi CD11b- CD103- MHCII- SiglecF+, Lung, avg-3	AXL TF LRP1 KCNN3	7.69e-04	83	105	4	GSM538282_100
CoexpressionAtlas	AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_500	SFRP2 CHRDL2 AFF3 TF SVEP1 SLPI AHSG ADAMTS18 KCNQ2	7.96e-04	496	105	9	Arv_EB-LF_500
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500	THSD4 VLDLR SFRP2 CRIM1 SPINT1 DLL1 ARFGEF3 FMN1	8.14e-04	398	105	8	gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlas	Stem Cells, SC.STSL.BM, CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Bone marrow, avg-3	VLDLR ARHGAP32 IGFBP4 ZNF608	8.41e-04	85	105	4	GSM399454_100
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#2	COL2A1 BOC BNC2 FBN1 RASAL3 NFATC4 WFIKKN2 ARID5B MACF1 ADAMTSL2	8.55e-04	607	105	10	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K2
CoexpressionAtlas	cervix, uterine	THSD4 ADAMTS19 SFRP1 SLPI COL14A1	8.74e-04	149	105	5	cervix, uterine
CoexpressionAtlas	Myeloid Cells, MF.II-480hi.PC, F4/80hi CD115hi CD11b+ MHC II- CD11c-, Peritoneal Cavity, avg-3	SELP TF SLPI LRP1	8.78e-04	86	105	4	GSM605850_100
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	BNC2 SFRP1 SVEP1 TGFBR3 FBLN1 FBN1 LRP1	8.87e-04	310	105	7	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500	SETD1A VLDLR BNC2 SFRP1 AFF3 NSD3 LRP1 ZNF445	9.25e-04	406	105	8	gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#4_top-relative-expression-ranked_500	SETD1A VLDLR AFF3 ARID5B ZNF445	9.56e-04	152	105	5	gudmap_developingGonad_e18.5_epididymis_500_k4
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000	BNC2 COL7A1 SFRP2 AXL ADGRB2 IL17D RASAL3 FMN1 WFIKKN2 ARID5B KCNN3 COL14A1 LTBP3	9.64e-04	967	105	13	Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000	BNC2 COL7A1 SFRP2 AXL ADGRB2 IL17D RASAL3 FMN1 WFIKKN2 ARID5B KCNN3 COL14A1 LTBP3	9.64e-04	967	105	13	Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200	BNC2 ZFPM2 FBN1 LRP1 COL14A1	9.85e-04	153	105	5	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_200
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000	BNC2 SFRP1 AXL AFF3 SVEP1 ZFPM2 FBN1 TRANK1 ARID5B LRP1 COL14A1 CCN2	9.95e-04	849	105	12	gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BOC BNC2 SFRP1 SFRP2 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 LTBP2	2.63e-15	195	111	13	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	Fibroblasts-CD34+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	BOC BNC2 SFRP1 SFRP2 SVEP1 TGFBR3 FBLN1 FBN1 IGFBP4 SLPI LRP1 COL14A1 CCN2	3.43e-15	199	111	13	13ff7409e200a0b46cdb7924d15ef33639693622
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SFRP1 SFRP2 AXL SVEP1 TGFBR3 FBLN1 FBN1 IGFBP4 SLPI LRP1 COL14A1 LTBP2 FST	3.66e-15	200	111	13	db6281b5d4032116310db379d9175d790994c99c
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SFRP1 SFRP2 AXL SVEP1 TGFBR3 FBLN1 FBN1 IGFBP4 SLPI LRP1 COL14A1 LTBP2 FST	3.66e-15	200	111	13	10f0c20ba7c71d9e2e177597f85b41cb40f0d878
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SFRP1 SFRP2 AXL SVEP1 TGFBR3 FBLN1 FBN1 IGFBP4 SLPI LRP1 COL14A1 LTBP2 FST	3.66e-15	200	111	13	a2bb67a06757f19be3f56f8cb5bb7e2affa5f4ed
ToppCell	droplet-Heart-nan-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR SFRP1 SFRP2 AXL TMPRSS6 AFF3 IL17D FBLN1 IGFBP4 LRP1 COL14A1 LTBP3	7.96e-14	194	111	12	20a0439fa02c5f8107612e34c7ab54120b9b8573
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS19 BNC2 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 MOV10L1 LRP1 KCNN3 COL14A1 LTBP2	9.56e-14	197	111	12	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC SFRP1 SFRP2 SVEP1 TGFBR3 FBLN1 FBN1 IGFBP4 SLPI LRP1 COL14A1 LTBP2	1.15e-13	200	111	12	cfea2f9d85646c9b722150551ff2e8fc4f6cc98a
ToppCell	droplet-Heart-nan-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR AXL TMPRSS6 AFF3 TGFBR3 FBLN1 IGFBP4 SLPI LRP1 AHSG COL14A1	7.12e-13	174	111	11	cf4e0567f2a4ebe5534046b1c091af59b55bdc4f
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	BOC BNC2 SFRP1 SFRP2 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 IGFBP4 COL14A1	1.39e-12	185	111	11	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BOC BNC2 CHRDL2 LDLRAD3 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 LRP1 LTBP2	1.66e-12	188	111	11	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	BOC BNC2 SFRP2 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1	1.66e-12	188	111	11	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BOC BNC2 SFRP2 SVEP1 TGFBR3 FBLN1 FBN1 NFATC4 LRP1 COL14A1 LTBP2	1.76e-12	189	111	11	d531399749409d614adca13d181830c6e3287508
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SFRP2 IL17D SVEP1 FBLN1 FBN1 SLPI LRP1 COL14A1 CCN2 LTBP2 FST	2.09e-12	192	111	11	f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SFRP2 IL17D SVEP1 FBLN1 FBN1 SLPI LRP1 COL14A1 CCN2 LTBP2 FST	2.09e-12	192	111	11	41a8326cd5bc19ad5041068501bab4c72399222e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BOC ADAMTS19 VLDLR BNC2 SFRP2 SVEP1 ZFPM2 FBLN1 FBN1 IGFBP4 COL14A1	2.09e-12	192	111	11	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	BOC BNC2 SFRP2 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 IGFBP4 NFATC4 COL14A1	2.09e-12	192	111	11	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	droplet-Fat-Mat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC VLDLR SFRP1 AXL SVEP1 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 LTBP3	2.21e-12	193	111	11	ebd090d7801480b3cee45caac3d30cc991836769
ToppCell	droplet-Fat-Mat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC VLDLR SFRP1 AXL SVEP1 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 LTBP3	2.21e-12	193	111	11	22c58032e58730715224d7934968ce92d150b0e8
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 AXL TMPRSS6 SVEP1 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 CCN2 LTBP3	2.21e-12	193	111	11	0a665531d581d4e3941e29d3f95569da8f166447
ToppCell	LA\|World / Chamber and Cluster_Paper	CACNA1E BNC2 AFF3 LRP1B SVEP1 TGFBR3 FBLN1 FBN1 SLPI LRP1 LTBP2	2.21e-12	193	111	11	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 AXL TMPRSS6 SVEP1 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 CCN2 LTBP3	2.21e-12	193	111	11	24ce1f37cca655415410d2403a52d1ebb3332280
ToppCell	droplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC VLDLR SFRP1 AXL SVEP1 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 LTBP3	2.21e-12	193	111	11	573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 AXL TMPRSS6 SVEP1 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 CCN2 LTBP3	2.34e-12	194	111	11	2d0cff9dc538a14518741e2a96d9d78442c81a72
ToppCell	droplet-Heart-nan-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 SFRP2 AXL TMPRSS6 AFF3 IL17D FBLN1 IGFBP4 LRP1 COL14A1 LTBP3	2.48e-12	195	111	11	613bea20c3d82c22a6af4c1a668af6fcf11fec0a
ToppCell	droplet-Heart-nan-18m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 SFRP2 AXL TMPRSS6 AFF3 IL17D FBLN1 IGFBP4 LRP1 COL14A1 LTBP3	2.48e-12	195	111	11	9ffabd831c2a0de3597f328e83db7ee259cb0ccc
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SFRP2 SVEP1 FBLN1 FBN1 SLPI ARID5B LRP1 COL14A1 CCN2 LTBP2 FST	2.48e-12	195	111	11	47762d9e442fb1f6f0033e3e10f4c6e498d2c081
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP1 SFRP2 IL17D ZFPM2 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 LTBP2	2.77e-12	197	111	11	c747c496ac090309b7f8a3e9d840928f12c83f2f
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 THSD4 BOC IL17D LDLRAD3 TGFBR3 FBLN1 FBN1 LRP1 CCN2 LTBP3	2.92e-12	198	111	11	d3a475be01657a03fcbb0ee0a246b1e90deacaa4
ToppCell	droplet-Trachea-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL2A1 THSD4 BOC IL17D LDLRAD3 TGFBR3 FBLN1 FBN1 LRP1 CCN2 LTBP3	2.92e-12	198	111	11	1beed34f469aad07e8f674f0b668d6e1e916403c
ToppCell	droplet-Trachea-nan-3m-Mesenchymal\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 THSD4 BOC IL17D LDLRAD3 TGFBR3 FBLN1 FBN1 LRP1 CCN2 LTBP3	2.92e-12	198	111	11	985022c1722ab7b67675ebe814022a439e715b5e
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC VLDLR SFRP1 SFRP2 TSPAN5 SVEP1 ZFPM2 FBLN1 FBN1 IGFBP4 COL14A1	3.09e-12	199	111	11	103f657132e830a0e5efeb745afb4b77c208a1fa
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BOC BNC2 SFRP1 SFRP2 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 IGFBP4 COL14A1	3.09e-12	199	111	11	f835e7ffe976843b0edbf695762d463da85793f3
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BOC BNC2 SFRP1 SFRP2 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 IGFBP4 COL14A1	3.09e-12	199	111	11	993fa050a095017135a6e723c77cd38b9d782e58
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC SFRP1 SFRP2 SVEP1 TGFBR3 FBLN1 FBN1 SLPI LRP1 COL14A1 LTBP2	3.26e-12	200	111	11	933b5b400e48a511ba0a056be1d33d3610b5f10d
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BOC BNC2 SFRP2 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1	3.26e-12	200	111	11	ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 SFRP2 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 LTBP2	3.26e-12	200	111	11	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	tumor_Lung-Fibroblasts\|tumor_Lung / Location, Cell class and cell subclass	BOC SFRP2 SVEP1 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 CCN2 LTBP2 ADAMTSL2	3.26e-12	200	111	11	073a68b5ce232203ffee86342cba2a00d907e119
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BOC BNC2 SFRP1 SFRP2 SVEP1 ZFPM2 FBLN1 FBN1 IGFBP4 LRP1 COL14A1	3.26e-12	200	111	11	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BOC GPRASP1 BNC2 CRIM1 ZFPM2 TGFBR3 NFATC4 OTOGL LTBP2 FST	1.33e-11	166	111	10	94636dbc039f794c735960c3425e00bdd5523602
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BOC SFRP1 SFRP2 SVEP1 TGFBR3 FBLN1 FBN1 NFATC4 LRP1 COL14A1	1.89e-11	172	111	10	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	BOC SFRP2 CHRDL2 SVEP1 FBLN1 FBN1 COL14A1 CCN2 LTBP2 FST	2.38e-11	176	111	10	510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCell	356C-Fibroblasts-Fibroblast-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	SNHG28 BOC SFRP1 SFRP2 SVEP1 FBLN1 FBN1 COL14A1 FST ADAMTSL2	2.66e-11	178	111	10	a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell	356C-Fibroblasts-Fibroblast-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	SNHG28 BOC SFRP1 SFRP2 SVEP1 FBLN1 FBN1 COL14A1 FST ADAMTSL2	2.66e-11	178	111	10	371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC BNC2 SFRP1 SVEP1 TGFBR3 FBLN1 IGFBP4 NFATC4 LRP1 ADAMTSL2	3.89e-11	185	111	10	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BNC2 CHRDL2 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 LRP1 CCN2 LTBP2	3.89e-11	185	111	10	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	BOC BNC2 SFRP1 SFRP2 SVEP1 ZFPM2 FBLN1 FBN1 NFATC4 COL14A1	3.89e-11	185	111	10	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	facs-Trachea-nan-24m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 AXL TMPRSS6 SVEP1 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 FST	4.33e-11	187	111	10	b930d5f7d410ac1f340babec5c937388f64cafc0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 AFF3 LDLRAD3 SVEP1 ZFPM2 FBLN1 FBN1 LRP1 COL14A1 ADAMTSL2	5.06e-11	190	111	10	2306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 AXL TMPRSS6 SVEP1 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 LTBP2	5.06e-11	190	111	10	d13fd234caa3fc69d8a59bc0060cdacdf716ee55
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 AFF3 LDLRAD3 SVEP1 ZFPM2 FBLN1 FBN1 LRP1 COL14A1 ADAMTSL2	5.06e-11	190	111	10	1f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ADAMTS19 BNC2 SFRP1 SFRP2 TSPAN5 ZFPM2 FBLN1 IGFBP4 COL14A1 CCN2	5.06e-11	190	111	10	4f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCell	droplet-Heart-nan-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 AXL TMPRSS6 IL17D FBLN1 IGFBP4 LRP1 CCN2 LTBP3 FST	5.33e-11	191	111	10	1f660ea2841324d13f63e01f1789e606c2843fc4
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP2 AXL TMPRSS6 AFF3 FBLN1 FBN1 LRP1 COL14A1 CCN2 FST	5.33e-11	191	111	10	1b26056df078674f37a6c06f6256b30cfcec21a7
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	BOC ADAMTS19 BNC2 SFRP2 SVEP1 ZFPM2 FBLN1 FBN1 IGFBP4 COL14A1	5.61e-11	192	111	10	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	facs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 AXL IL17D SVEP1 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 FST	5.91e-11	193	111	10	735a72fac16397edde95e8eefa6f83caeb5ee5df
ToppCell	droplet-Heart-nan-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 AXL TMPRSS6 IL17D FBLN1 IGFBP4 LRP1 CCN2 LTBP3 FST	5.91e-11	193	111	10	0ca0439dfdcb2361ca8d1015fb874a5b5c635d31
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 AFF3 LDLRAD3 SVEP1 ZFPM2 FBLN1 FBN1 LRP1 COL14A1 ADAMTSL2	5.91e-11	193	111	10	f1199518c3626fd29bfce65070dd21a660671213
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC AXL TMPRSS6 SVEP1 TGFBR3 FBLN1 FBN1 LRP1 COL14A1 LTBP3	5.91e-11	193	111	10	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BOC ADAMTS19 BNC2 SFRP2 SVEP1 ZFPM2 FBLN1 FBN1 IGFBP4 COL14A1	5.91e-11	193	111	10	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	droplet-Heart-nan-24m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 AXL TMPRSS6 IL17D FBLN1 IGFBP4 LRP1 CCN2 LTBP3 FST	5.91e-11	193	111	10	d08919db9601941569b9a143dad4d8e6f56a4389
ToppCell	facs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 AXL IL17D SVEP1 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 FST	5.91e-11	193	111	10	ff901d2f3d7a511639c1e3b76058896c0d8a8602
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 AXL AFF3 SVEP1 ZFPM2 FBLN1 TRANK1 NFATC4 LRP1 ADAMTSL2	6.22e-11	194	111	10	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 AXL AFF3 IL17D FBLN1 FBN1 IGFBP4 LRP1 COL14A1 ADAMTSL2	6.22e-11	194	111	10	ce32e60bcea1b8baf496ce9050832bc8c77d8434
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC VLDLR SFRP1 AXL IL17D SVEP1 FBLN1 IGFBP4 LRP1 COL14A1	6.22e-11	194	111	10	da926441053b499cb5107ccb116fb1b3844d82b7
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 AXL AFF3 IL17D FBLN1 FBN1 IGFBP4 LRP1 COL14A1 ADAMTSL2	6.22e-11	194	111	10	a1dc157148885cc8d3685ac81a1f4e3562aeecc9
ToppCell	facs-Heart-RA-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 SFRP2 AXL IL17D FBLN1 IGFBP4 LRP1 COL14A1 CCN2 ADAMTSL2	6.22e-11	194	111	10	c422aeddb4e949a22f731da675bdf91dee86ba61
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SFRP1 AFF3 SVEP1 FBLN1 FBN1 LRP1 COL14A1 CCN2 ADAMTSL2	6.22e-11	194	111	10	240d122dcb9dd1ab2867503ad85869853adcacae
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SFRP2 SVEP1 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 LTBP2 FST	6.22e-11	194	111	10	02b8102be9414d6964cd71019613edff6d88b893
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SFRP1 AFF3 SVEP1 FBLN1 FBN1 LRP1 COL14A1 CCN2 ADAMTSL2	6.22e-11	194	111	10	ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC VLDLR SFRP1 AXL IL17D SVEP1 FBLN1 IGFBP4 LRP1 COL14A1	6.22e-11	194	111	10	54a7f693966b5c02f6b248950ddb5fa32af3ae67
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 AFF3 SVEP1 ZFPM2 FBLN1 FBN1 NFATC4 LRP1 COL14A1 ADAMTSL2	6.22e-11	194	111	10	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC VLDLR SFRP1 AXL IL17D SVEP1 FBLN1 IGFBP4 LRP1 COL14A1	6.22e-11	194	111	10	f34b3bbdebf56f66ff499e390e5515a4a4093f90
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 AXL AFF3 SVEP1 ZFPM2 FBLN1 TRANK1 NFATC4 LRP1 ADAMTSL2	6.22e-11	194	111	10	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	facs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC VLDLR SFRP1 AXL SVEP1 TGFBR3 FBLN1 FBN1 COL14A1 LTBP3	6.54e-11	195	111	10	69a29d03e664b72f32d41876510c62345c3aed31
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	BOC BNC2 LDLRAD3 SVEP1 TGFBR3 FBLN1 FBN1 LRP1 CCN2 LTBP2	6.54e-11	195	111	10	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 AXL AFF3 SVEP1 ZFPM2 FBLN1 FBN1 NFATC4 LRP1 ADAMTSL2	6.54e-11	195	111	10	edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell	facs-GAT-Fat-3m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC VLDLR SFRP1 AXL SVEP1 TGFBR3 FBLN1 FBN1 COL14A1 LTBP3	6.54e-11	195	111	10	1cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 SFRP1 AFF3 SVEP1 FBLN1 FBN1 LRP1 COL14A1 CCN2 ADAMTSL2	6.54e-11	195	111	10	44d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP2 CHRDL2 SVEP1 FBLN1 FBN1 IGFBP4 NFATC4 COL14A1 CCN2 LTBP2	6.54e-11	195	111	10	51db90e7611f7d69980878c046505ff34212079b
ToppCell	facs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC VLDLR SFRP1 AXL SVEP1 TGFBR3 FBLN1 FBN1 COL14A1 LTBP3	6.54e-11	195	111	10	9cef6f18664518060af7c192310dddce6d70345a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 AXL AFF3 LDLRAD3 SVEP1 ZFPM2 FBN1 LRP1 LTBP2 ADAMTSL2	6.88e-11	196	111	10	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC BNC2 SFRP1 LDLRAD3 FBLN1 FMN1 MACF1 CCN2 LTBP2 FST	6.88e-11	196	111	10	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 AXL AFF3 LDLRAD3 SVEP1 ZFPM2 FBN1 LRP1 LTBP2 ADAMTSL2	6.88e-11	196	111	10	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	facs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 AXL TMPRSS6 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 ADAMTSL2	6.88e-11	196	111	10	ad1838dabd043cb140260843e3527d8c7d58850e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SFRP1 AFF3 LDLRAD3 SVEP1 FBLN1 FBN1 LRP1 COL14A1 CCN2 ADAMTSL2	6.88e-11	196	111	10	ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SFRP1 AFF3 LDLRAD3 SVEP1 FBLN1 FBN1 LRP1 COL14A1 CCN2 ADAMTSL2	6.88e-11	196	111	10	30ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCell	facs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP1 AXL TMPRSS6 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 ADAMTSL2	6.88e-11	196	111	10	cbc15c0769016fe9972445169029bd8d14a7e6ef
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 AFF3 LDLRAD3 SVEP1 ZFPM2 FBLN1 FBN1 LRP1 COL14A1 ADAMTSL2	7.23e-11	197	111	10	6d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP2 IL17D SVEP1 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 LTBP2	7.23e-11	197	111	10	71786e9432e2d649f5d86f639abb25e7102deb67
ToppCell	tumor_Lung-Fibroblasts-COL14A1+_matrix_FBs\|tumor_Lung / Location, Cell class and cell subclass	BOC BNC2 SFRP1 SFRP2 SVEP1 FBLN1 FBN1 IGFBP4 LRP1 COL14A1	7.60e-11	198	111	10	74f2c7ef702b25a5b99e56121229e678ed992524
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP2 IL17D SVEP1 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 LTBP2	7.99e-11	199	111	10	9672230aa0bc6a7289050c955f5154ca183a5159
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP2 IL17D SVEP1 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 LTBP2	7.99e-11	199	111	10	e18abe678da293bd01fae55e2f9ab6fdd643d02d
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP2 IL17D SVEP1 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1 LTBP2	7.99e-11	199	111	10	1fd7bbb8727607e6507848602a19bc86882ef2d5
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC VLDLR SFRP1 SFRP2 IL17D TSPAN5 ZFPM2 IGFBP4 KCNQ2 COL14A1	7.99e-11	199	111	10	83383d9ae4f501754fd3da0215ce6f0e3c70562c
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BOC BNC2 SFRP2 LDLRAD3 SVEP1 TGFBR3 FBLN1 FBN1 LRP1 COL14A1	7.99e-11	199	111	10	abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP1 SFRP2 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 IGFBP4 LRP1 COL14A1	8.39e-11	200	111	10	17ffdbc13332bd3ed1d54abcd7af20267dd4b234
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BOC BNC2 SVEP1 ZFPM2 TGFBR3 FBLN1 FBN1 LRP1 COL14A1 LTBP2	8.39e-11	200	111	10	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_adventitial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	BOC BNC2 SFRP1 SFRP2 AXL SVEP1 FBLN1 FBN1 LRP1 COL14A1	8.39e-11	200	111	10	fc3c4778841c4b8bac0afb458352614b2c460617
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	BOC BNC2 SFRP1 SFRP2 SVEP1 TGFBR3 FBLN1 FBN1 COL14A1 LTBP2	8.39e-11	200	111	10	954fee8425673e76198be414f5f6c4e3597c1919
Computational	Metal / Ca ion binding.	ADAM9 TF FBLN1 FBN1 LRP1 LTBP2	2.20e-04	133	70	6	MODULE_324
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SFRP2 FBLN1 FBN1 CCN2	3.03e-04	50	70	4	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_1
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SFRP1 SFRP2 FBLN1 COL14A1	3.03e-04	50	70	4	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_COMPLEMENT
Computational	Ovary genes.	SFRP1 CRIM1 TGFBR3 FBLN1 FBN1 IGFBP4 SLPI LRP1 LTBP2	6.02e-04	368	70	9	MODULE_1
Computational	ECM and collagens.	ADAM9 FBLN1 FBN1 IGFBP4 LRP1 CCN2 LTBP2	6.27e-04	225	70	7	MODULE_47
Computational	DRG (dorsal root ganglia) genes.	SFRP1 CRIM1 TGFBR3 FBLN1 FBN1 IGFBP4 SLPI LRP1 LTBP2	8.16e-04	384	70	9	MODULE_2
Drug	LMWH	COL2A1 SELP BOC COL7A1 SGSH ADAM9 TGFBR3 FBLN1 IGFBP4 SLPI LRP1 KCNQ2 COL14A1 CCN2 FST	4.96e-07	663	107	15	CID000000772
Disease	Geleophysic dysplasia	FBN1 LTBP3 ADAMTSL2	3.87e-07	5	101	3	C3489726
Disease	Acromicric Dysplasia	FBN1 LTBP3 ADAMTSL2	3.87e-07	5	101	3	C0265287
Disease	FEV/FEC ratio	THSD4 BOC BNC2 SFRP1 SFRP2 CRIM1 AFF3 DENND3 TGFBR3 FBLN1 FBN1 LRP1 KCNN3 LTBP2 LTBP3 FST	4.20e-06	1228	101	16	EFO_0004713
Disease	central corneal thickness	ADAMTS19 SFRP1 CRIM1 AFF3 FBN1 ARID5B ADAMTS18 FST	1.15e-05	309	101	8	EFO_0005213
Disease	pulse pressure measurement	COL2A1 THSD4 DIP2B BNC2 CRIM1 SSPOP TSPAN5 SVEP1 ZFPM2 NSD3 TGFBR3 FBN1 TRANK1 LRP1 LTBP2 LTBP3	2.00e-05	1392	101	16	EFO_0005763
Disease	cortical thickness	THSD4 DIP2B BNC2 SFRP1 CRIM1 SYBU DENND3 FBN1 XPO5 UMODL1 FSHR LRP1 ADAMTS18 MACF1	2.62e-05	1113	101	14	EFO_0004840
Disease	Weill-Marchesani syndrome	FBN1 LTBP2	3.47e-05	3	101	2	C0265313
Disease	Weill-Marchesani Syndrome, Autosomal Dominant	FBN1 LTBP2	3.47e-05	3	101	2	C1869115
Disease	Weill-Marchesani Syndrome, Autosomal Recessive	FBN1 LTBP2	3.47e-05	3	101	2	C1869114
Disease	cortical surface area measurement	COL2A1 THSD4 ADAMTS19 BNC2 SFRP1 SFRP2 CHRDL2 FAM117B SYBU DENND3 SVEP1 FBN1 FSHR ADAMTS18 MACF1	5.26e-05	1345	101	15	EFO_0010736
Disease	Weill-Marchesani syndrome	FBN1 LTBP2	6.93e-05	4	101	2	cv:C0265313
Disease	Weill-Marchesani syndrome (is_implicated_in)	FBN1 LTBP2	6.93e-05	4	101	2	DOID:0050475 (is_implicated_in)
Disease	electrocardiography	SFRP1 CHRDL2 CRIM1 AXL IL17D ZFPM2 TRANK1 KCNN3 ADAMTS18	8.79e-05	530	101	9	EFO_0004327
Disease	Seizures	CACNA1E SGSH AFF3 DLL1 KCNQ2 MACF1	1.07e-04	218	101	6	C0036572
Disease	cup-to-disc ratio measurement	THSD4 ADAMTS19 BNC2 EZH1 TGFBR3 ARID5B LTBP2 LTBP3	1.18e-04	430	101	8	EFO_0006939
Disease	spontaneous coronary artery dissection	THSD4 FBN1 LRP1	1.63e-04	31	101	3	EFO_0010820
Disease	corneal resistance factor	ADAMTS19 SFRP1 AFF3 TGFBR3 FBN1 ARID5B ADAMTS18 FST	1.64e-04	451	101	8	EFO_0010067
Disease	disease recurrence, unipolar depression, bipolar disorder, schizophrenia, sex interaction measurement	THSD4 ADAMTS19 LRP1B	1.97e-04	33	101	3	EFO_0003761, EFO_0004952, EFO_0008343, MONDO_0004985, MONDO_0005090
Disease	Drug toxicity	TF AFM ARID5B AHSG	2.02e-04	84	101	4	C0013221
Disease	Adverse reaction to drug	TF AFM ARID5B AHSG	2.02e-04	84	101	4	C0041755
Disease	cholesteryl ester 16:2 measurement	LTBP2 LTBP3	2.41e-04	7	101	2	EFO_0021435
Disease	Stevens-Johnson syndrome, toxic epidermal necrolysis, response to cold medicine	IL17D LTBP2 LTBP3	2.78e-04	37	101	3	EFO_0004276, EFO_0004775, EFO_0006997
Disease	Rheumatoid Arthritis	COL2A1 AFF3 CD83 ARID5B CCN2	3.38e-04	174	101	5	C0003873
Disease	intraocular pressure measurement	AFF3 ADGRB2 FBN1 ARID5B ADAMTS18 LTBP2 LTBP3 FST	3.69e-04	509	101	8	EFO_0004695
Disease	asparaginase-induced acute pancreatitis	C3orf20 ADAMTS18	4.11e-04	9	101	2	EFO_1001507
Disease	vascular endothelial growth factor A, isoform 121 measurement	VLDLR ZFPM2	4.11e-04	9	101	2	EFO_0020847
Disease	birth weight	VLDLR ZFPM2 PIM3 P2RX4 UMODL1 KCNN3 USH2A	4.53e-04	399	101	7	EFO_0004344
Disease	macula measurement	COL2A1 ARHGAP32 SFRP2 TTK FBN1	4.93e-04	189	101	5	EFO_0008375
Disease	aortic aneurysm	FBN1 LRP1	5.13e-04	10	101	2	EFO_0001666
Disease	Epilepsy	SETD1A P2RX4 SCN1A KCNQ2	5.46e-04	109	101	4	C0014544
Disease	response to hydrochlorothiazide, triglyceride measurement	DAB2IP THSD4 KLRD1	5.66e-04	47	101	3	EFO_0004530, EFO_0005202
Disease	chronic obstructive pulmonary disease	THSD4 BOC SETD1A BNC2 SFRP1 SFRP2 ZSCAN12 CRIM1 AFF3	6.00e-04	688	101	9	EFO_0000341
Disease	brain measurement, neuroimaging measurement	COL2A1 THSD4 ADAMTS19 DIP2B SFRP2 DENND3 ADAMTS18 MACF1	6.14e-04	550	101	8	EFO_0004346, EFO_0004464
Disease	Marfan Syndrome	FBN1 LTBP2	6.25e-04	11	101	2	C0024796
Disease	congenital diaphragmatic hernia (implicated_via_orthology)	ZFPM2 LRP1	7.49e-04	12	101	2	DOID:3827 (implicated_via_orthology)
Disease	iron biomarker measurement, serum iron measurement	TMPRSS6 TF	7.49e-04	12	101	2	EFO_0004461, EFO_0006332
Disease	Mitral valve prolapse, response to surgery	LTBP2 LTBP3	7.49e-04	12	101	2	EFO_0009951, HP_0001634
Disease	vascular endothelial growth factor A measurement	VLDLR ZFPM2	7.49e-04	12	101	2	EFO_0010804
Disease	stenosing tenosynovitis	LTBP2 LTBP3	7.49e-04	12	101	2	EFO_0010822
Disease	polychlorinated biphenyls measurement, gestational serum measurement	FMN1 FST	7.49e-04	12	101	2	EFO_0007042, EFO_0007964
Disease	C-reactive protein measurement	BNC2 SFRP2 ORC3 SSPOP ZFPM2 TRANK1 P2RX4 ZNF608 KCNN3 MACF1 FST KDF1	8.59e-04	1206	101	12	EFO_0004458
Disease	severe acute respiratory syndrome, COVID-19	THSD4 USP9X LRP1B ZFPM2 TGFBR3 LTBP2 LTBP3	8.84e-04	447	101	7	EFO_0000694, MONDO_0100096
Disease	hepcidin:ferritin ratio	TMPRSS6 LRP1B FBN1	8.97e-04	55	101	3	EFO_0007901
Disease	total blood protein measurement	CRIM1 AFF3 TF ZFX ARID5B MACF1 ARHGAP45	9.08e-04	449	101	7	EFO_0004536
Disease	response to methotrexate, aspartate aminotransferase measurement	THSD4 SELP	1.03e-03	14	101	2	EFO_0004736, GO_0031427
Disease	iron biomarker measurement, transferrin saturation measurement	TMPRSS6 TF	1.03e-03	14	101	2	EFO_0004461, EFO_0006333
Disease	neuroimaging measurement	COL2A1 THSD4 DIP2B SFRP1 SFRP2 AFF3 TF DENND3 FSHR ADAMTS18 MACF1	1.09e-03	1069	101	11	EFO_0004346
Disease	colorectal cancer	THSD4 BOC DIP2B CHRDL2 FBN1 FMN1 LRP1 MACF1	1.12e-03	604	101	8	MONDO_0005575
Disease	Malignant neoplasm of breast	BOC ADAMTS19 COL7A1 SFRP1 SFRP2 TMPRSS6 DLL1 APOBEC3B OTOGL MACF1 FST	1.13e-03	1074	101	11	C0006142
Disease	interferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement	VLDLR ZFPM2	1.35e-03	16	101	2	EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Disease	Spondyloepiphyseal Dysplasia	COL2A1 ADAMTSL2	1.35e-03	16	101	2	C0038015
Disease	transferrin saturation measurement	TMPRSS6 TF	1.35e-03	16	101	2	EFO_0006333
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	COL2A1 ADAMTSL2	1.35e-03	16	101	2	C3541456
Disease	Schwartz-Jampel Syndrome, Type 1	COL2A1 ADAMTSL2	1.35e-03	16	101	2	C4551479
Disease	Schwartz-Jampel Syndrome	COL2A1 ADAMTSL2	1.35e-03	16	101	2	C0036391
Disease	Melnick-Needles Syndrome	COL2A1 ADAMTSL2	1.35e-03	16	101	2	C0025237
Disease	ascending aortic diameter	THSD4 C3orf20 FBN1 ARID5B	1.39e-03	140	101	4	EFO_0021787
Disease	Headache	TGFBR3 LRP1 MACF1	1.39e-03	64	101	3	HP_0002315
Disease	sexual dimorphism measurement	DIP2B COL7A1 CRIM1 FBN1 TRANK1 IGFBP4 ZNF608 NFATC4 MACF1 LTBP2 LTBP3	1.43e-03	1106	101	11	EFO_0021796
Disease	Van Buchem disease	COL2A1 ADAMTSL2	1.53e-03	17	101	2	C0432272
Disease	venous thromboembolism, fibrinogen measurement	DIP2B SFRP2 ZFPM2	1.59e-03	67	101	3	EFO_0004286, EFO_0004623
Disease	Takayasu arteritis	LRP1B SVEP1 ZFPM2 TRANK1	1.70e-03	148	101	4	EFO_1001857
Disease	serum hepcidin measurement	TMPRSS6 TF	1.71e-03	18	101	2	EFO_0004504
Disease	aortic measurement	THSD4 FBN1 ARID5B LRP1 ADAMTS18	1.75e-03	251	101	5	EFO_0020865
Disease	colorectal cancer, colorectal adenoma	BOC CHRDL2 FMN1 LRP1	1.88e-03	152	101	4	EFO_0005406, MONDO_0005575
Disease	Osteochondrodysplasias	COL2A1 ADAMTSL2	1.91e-03	19	101	2	C0029422
Disease	Dyschondroplasias	COL2A1 ADAMTSL2	1.91e-03	19	101	2	C0013366
Disease	response to methotrexate, neurotoxicity	DAB2IP MACF1	1.91e-03	19	101	2	EFO_0011057, GO_0031427
Disease	pentachlorophenol measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022071
Disease	parathion measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022070
Disease	potassium chromate measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022072
Disease	mercuric chloride measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022068
Disease	heptachlor epoxide measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022067
Disease	methoxychlor measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022069
Disease	4,6-dinitro-o-cresol measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022053
Disease	2,4,5-trichlorophenol measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022052
Disease	azinphos methyl measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022055
Disease	aldrin measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022054
Disease	dicofol measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022060
Disease	disulfoton measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022062
Disease	dieldrin measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022061
Disease	endrin measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022064
Disease	endosulfan measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022063
Disease	heptachlor measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022066
Disease	ethion measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022065
Disease	chlorpyrifos measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022057
Disease	cadmium chloride measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022056
Disease	diazinon measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022059
Disease	dibutyl phthalate measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0022058
Disease	environmental exposure measurement	SELP SFRP1 USH2A	2.03e-03	73	101	3	EFO_0008360
Disease	DDT metabolite measurement	SELP SFRP1 USH2A	2.12e-03	74	101	3	EFO_0007886
Disease	iron biomarker measurement, transferrin measurement	TMPRSS6 TF	2.12e-03	20	101	2	EFO_0004461, EFO_0006341
Disease	Multiple Epiphyseal Dysplasia	COL2A1 ADAMTSL2	2.12e-03	20	101	2	C0026760
Disease	serum IgG glycosylation measurement	CACNA1E LRP1B UMODL1 FMN1 ARID5B FST USH2A	2.17e-03	523	101	7	EFO_0005193
Disease	myocardial infarction (biomarker_via_orthology)	SELP SFRP2 SLPI CCN2	2.26e-03	160	101	4	DOID:5844 (biomarker_via_orthology)
Disease	Congenital diaphragmatic hernia	ZFPM2 CCN2	2.33e-03	21	101	2	C0235833
Disease	epilepsy (implicated_via_orthology)	CACNA1E LRP1B SCN1A LRP1	2.42e-03	163	101	4	DOID:1826 (implicated_via_orthology)
Disease	apolipoprotein A 1 measurement	COL7A1 AFF3 TF ZFPM2 PIM3 C1orf220 TRANK1 LRP1 MACF1	2.54e-03	848	101	9	EFO_0004614
Disease	age of onset of asthma	AFF3 LTBP2 LTBP3	2.55e-03	79	101	3	OBA_2001001
Disease	otosclerosis	AHSG LTBP2 LTBP3	2.74e-03	81	101	3	EFO_0004213

Protein segments in the cluster

Peptide	Gene	Start	Entry
SPCSLDIDCPGLEKC	UMODL1	131	Q5DID0
PCEGTGEEVKPCSEK	ADGRB2	511	O60241
DCGKVPDVCQPSLRE	AFF3	506	P51826
SCLGEKGCEPDTTAP	CACNA1E	1671	Q15878
PCPDCVAKLAEFLSE	APOBEC3B	96	Q9UH17
EDPCEGENKCSEPRA	AKAP4	646	Q5JQC9
SPEGDLCSSPDPKIC	BNC2	821	Q6ZN30
CKAESPEVCFNEESP	AFM	581	P43652
AGTPCRKSIDPECDF	ADAM18	446	Q9Y3Q7
CFPGGVCVATEPKED	DENND3	46	A2RUS2
FCPAPEKREDPSCVD	ADAMTS18	1176	Q8TE60
DVKDCLSPEIPFGEC	COL2A1	71	P02458
CCPGSPDIDKLDVAT	ESRP1	146	Q6NXG1
TEDCEVDPSKCPASE	RASAL3	536	Q86YV0
CLGALVDTCPIKPEA	PYY3	21	Q5JQD4
CPEIPDATTVCKSDA	P2RX4	116	Q99571
CRTKLDPPMDGTDCD	ADAMTS19	601	Q8TE59
VLDEEKPCALFCSPV	ADAMTS19	716	Q8TE59
DVCISTDDDCPPKTF	FMN1	786	Q68DA7
KLDREELCGPTEPCV	PCDHB2	91	Q9Y5E7
PEVKVACSEDVDLPC	CD83	21	Q01151
NCEVDPSKCSAADLP	DAB2IP	451	Q5VWQ8
PAVCSLLPKEANCEG	KLHL36	251	Q8N4N3
GLPDCFDKSDEKECP	LDLRAD3	51	Q86YD5
PSLEDCDAGCLPAEE	ARHGAP45	256	Q92619
SDEDDCDSFLCGPPK	LRP1B	1126	Q9NZR2
SLESVCEGFEPCKGD	MOV10L1	141	Q9BXT6
SVPKRCDADAPEDQC	LMBRD1	461	Q9NUN5
TSVCLPPDKLCDGND	LRP1	1156	Q07954
DHSDEPPDCPEFKCR	LRP1	3361	Q07954
EEFLPPGASLKCTVC	ZFPM2	326	Q8WW38
DEDPKCPCPSSGDEQ	KCNN3	16	Q9UGI6
SLPGEDIVDDKSCPC	KCNQ2	511	O43526
KSCPCEFVTEDLTPG	KCNQ2	521	O43526
GLKPEAICPCATSAE	DIP2B	661	Q9P265
PKDIPLDCDCVLTGE	MACF1	411	O94854
ECGLAKKPPEESTCF	ADAMTSL2	836	Q86TH1
GCTCVPEPEKDADSI	IL17D	166	Q8TAD2
DELCPDSKSDEPVCA	FST	271	P19883
CKICPEDKADPGHSE	CHRDL2	311	Q6WN34
QCSPPKAESECLESG	ARHGAP32	801	A7KAX9
ECPSDVLPEQEGVCL	FAAP100	626	Q0VG06
CAPATDKAEEVVCAP	CRACDL	381	Q6NV74
LEACKSNCSPEPEDI	FAM170B	166	A6NMN3
SNCSPEPEDIDLLEC	FAM170B	171	A6NMN3
GTRCVDVDECAPPAE	FBLN1	351	P23142
VDGKESCESLSCLPP	KAT6A	176	Q92794
CEPAPECSSLEQEEL	CCPG1	36	Q9ULG6
CCLGLVPVEEVDSPD	BOC	1056	Q9BWV1
PDSAEDVRKVCQDCP	AHSG	136	P02765
ELGIDECDPSPCKNG	DLL1	326	O00548
GSDINECALDPDICP	FBN1	721	P35555
ELCTERDPCDPHKGL	CCN2	66	P29279
KCCELPGLRDDESCP	COL14A1	1431	Q05707
PEGCERVKVFEECSP	FAM117B	471	Q6P1L5
GEVDCKEIGDCAPAP	ARFGEF3	1366	Q5TH69
SDPCPEAREKLQELC	C3orf20	276	Q8ND61
DESKCEEPRNCPGSI	CRIM1	41	Q9NZV1
EECDCGTPKECELDP	ADAM9	426	Q13443
GTPKECELDPCCEGS	ADAM9	431	Q13443
GSECEKCPLPGTEAF	LTBP2	706	Q14767
PSPLGDSCEDVDECE	LTBP2	1126	Q14767
PAPDGRSCLDVDECE	LTBP3	776	Q9NS15
KCPELFAPEQGSLDC	SELP	571	P16109
DSDDPCSLPLDEGSC	COL7A1	2871	Q02388
DLCNEVVDVTCSPKP	FSHR	336	P23945
EAERLGPKSQCPAEC	C1orf220	21	Q5T0J3
ECDPLKCPSISTPEC	OTOGL	1971	Q3ZCN5
KSEEGCIPNIAPDIC	ORC3	616	Q9UBD5
PSADDNLKTPPECVC	NPIPA7	341	E9PJI5
PSADDNLKTPPECVC	NPIPA8	341	P0DM63
EVSEEAGPCCVSKPE	GPRASP1	916	Q5JY77
AGPCCVSKPEDDEEM	GPRASP1	921	Q5JY77
DPSAIDVCKPCDCDT	USH2A	631	O75445
TLAKACELCPEEEPD	USP9X	2466	Q93008
LLPATEEAPKVCEAC	SFRP2	161	Q96HF1
ECRDTQPPDGKSKDC	PLEKHB2	61	Q96CS7
DGVVLKPEPDDLCCV	TDRD6	531	O60522
SGPEAEEEPCLLQGC	SSPOP	3236	A2VEC9
DTCGIKCLDPVDTPN	SLPI	66	P03973
LGEELDSEDAPPCCR	NFATC4	31	Q14934
DSEDAPPCCRLALGE	NFATC4	36	Q14934
ECVDTPKVNGCLLDP	SIK2	416	Q9H0K1
GCDALPILKIPCSDT	OR6C68	176	A6NDL8
GDEAIHCPPCSEEKL	IGFBP4	21	P22692
APDADSCCKEPLADP	KDF1	181	Q8NAX2
CPPCDNELKSEAIIE	SFRP1	186	Q8N474
SCGKPAIPENGCIEE	SVEP1	1846	Q4LDE5
FPLEDNKIPCLCGTE	SETD1A	1686	O15047
CAPDGVLEEKLSPQC	SGSH	481	P51688
PEETLEPEACFTEGC	SCN1A	1171	P35498
ESKLCCFTESPESEP	ARID5B	576	Q14865
CPCDAETDQAPEGEK	ZDHHC6	396	Q9H6R6
REGTCPEAPTDECKP	TF	346	P02787
DELCLDFPCDSPEKS	SYBU	386	Q9NX95
CVDLPDTGLCKESIP	SPINT1	391	O43278
TVEPQDKCATCDFPL	VPS18	846	Q9P253
IKIEPEPCGTDCFLL	EZH1	326	Q92800
PDPKDSCSCLTAAEV	AXL	846	P30530
TDQKSCDPGLEDPCG	XPO5	701	Q9HAV4
PESCDLRLCTLDPDD	PIM3	301	Q86V86
KSAEPADCAEGPVQC	SNHG28	91	P0DPA3
DLSEIPRCNCKPADE	NSD3	1091	Q9BZ95
KPADENPCGLESECL	NSD3	1101	Q9BZ95
KGCPADLVVCDGAPD	FTSJ1	106	Q9UET6
GVPFSCCTKDPAEDV	TSPAN5	181	P62079
PSEEMPLEDCKEACS	ZNF445	946	P59923
SPDCDVKTDDSVVPC	TTK	281	P33981
EVGVVTEPECLGPCE	ZNF608	356	Q9ULD9
SEIDPCKVDGTCPEV	ZFX	236	P17010
QESCPEPEAVACKGD	ZNF835	31	Q9Y2P0
EATPCDNGPCTGKVE	THSD4	841	Q6ZMP0
EPPLGDCLIKDCNFS	TRANK1	411	O15050
PSACSREDKQPTCDE	ZSCAN12	236	O43309
SGKDCLLCFPETLPE	ZHX1-C8orf76	176	Q96EF9
PKCVPPDEACTSLDA	TGFBR3	721	Q03167
VPACDGVKDCPNGLD	TMPRSS6	471	Q8IU80
DPDCKDGSDEVNCPS	VLDLR	261	P98155
AECLKPPDSEDCGEE	WFIKKN2	326	Q8TEU8
PGPNIELQKDSDCCS	KLRD1	46	Q13241