Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RANBP2 ZMIZ2 RGPD3

3.51e-0920204GO:0061665
GeneOntologyMolecularFunctionstructural constituent of nuclear pore

NUP98 NUP62 NUP214 NUP54

9.13e-0925204GO:0017056
GeneOntologyMolecularFunctionSUMO transferase activity

RGPD4 RANBP2 ZMIZ2 RGPD3

4.22e-0836204GO:0019789
GeneOntologyMolecularFunctionGTPase activator activity

RGPD4 AGFG1 AGFG2 RANBP2 RGPD3

6.71e-06279205GO:0005096
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

RGPD4 RANBP2 RGPD3

1.63e-0550203GO:0003755
GeneOntologyMolecularFunctioncis-trans isomerase activity

RGPD4 RANBP2 RGPD3

1.95e-0553203GO:0016859
GeneOntologyMolecularFunctionGTPase regulator activity

RGPD4 AGFG1 AGFG2 RANBP2 RGPD3

1.17e-04507205GO:0030695
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RGPD4 AGFG1 AGFG2 RANBP2 RGPD3

1.17e-04507205GO:0060589
GeneOntologyMolecularFunctionstructural molecule activity

NUP98 OLFM4 NUP62 NUP214 NUP54 FLG2

1.76e-04891206GO:0005198
GeneOntologyMolecularFunctionsmall GTPase binding

RGPD4 RANBP2 RGPD3 KIF3B

2.59e-04321204GO:0031267
GeneOntologyMolecularFunctionnuclear localization sequence binding

NUP98 NUP214

3.30e-0427202GO:0008139
GeneOntologyMolecularFunctionenzyme activator activity

RGPD4 AGFG1 AGFG2 RANBP2 RGPD3

3.88e-04656205GO:0008047
GeneOntologyMolecularFunctionGTPase binding

RGPD4 RANBP2 RGPD3 KIF3B

4.01e-04360204GO:0051020
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

RGPD4 RANBP2 ZMIZ2 RGPD3

5.85e-04398204GO:0061659
GeneOntologyMolecularFunctionmolecular condensate scaffold activity

NUP98 TARDBP

8.01e-0442202GO:0140693
GeneOntologyMolecularFunctionisomerase activity

RGPD4 RANBP2 RGPD3

8.84e-04192203GO:0016853
GeneOntologyMolecularFunctionsignal sequence binding

NUP98 NUP214

1.18e-0351202GO:0005048
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

RGPD4 RANBP2 ZMIZ2 RGPD3

1.49e-03512204GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

RGPD4 RANBP2 ZMIZ2 RGPD3

1.72e-03532204GO:0016755
GeneOntologyMolecularFunctiontranscription coactivator activity

NUP98 ZMIZ2 TCF20

3.26e-03303203GO:0003713
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

NUP98 TARDBP NUP62 ZMIZ2 TCF20

4.89e-031160205GO:0030674
GeneOntologyMolecularFunctionmolecular function activator activity

RGPD4 AGFG1 AGFG2 RANBP2 RGPD3

6.33e-031233205GO:0140677
GeneOntologyMolecularFunctionacyltransferase activity

RGPD4 RANBP2 ZMIZ2 RGPD3

6.64e-03775204GO:0016746
GeneOntologyMolecularFunctionmolecular adaptor activity

NUP98 TARDBP NUP62 ZMIZ2 TCF20

9.41e-031356205GO:0060090
GeneOntologyMolecularFunctionenzyme regulator activity

RGPD4 AGFG1 AGFG2 RANBP2 RGPD3

1.13e-021418205GO:0030234
GeneOntologyMolecularFunctiontranscription coregulator activity

NUP98 ZMIZ2 TCF20

1.77e-02562203GO:0003712
GeneOntologyBiologicalProcessmRNA transport

NUP98 RGPD4 AGFG1 RANBP2 NUP62 NUP214 RGPD3 NUP54

5.76e-13145208GO:0051028
GeneOntologyBiologicalProcessRNA transport

NUP98 RGPD4 AGFG1 RANBP2 NUP62 NUP214 RGPD3 NUP54

2.64e-12175208GO:0050658
GeneOntologyBiologicalProcessnucleic acid transport

NUP98 RGPD4 AGFG1 RANBP2 NUP62 NUP214 RGPD3 NUP54

2.64e-12175208GO:0050657
GeneOntologyBiologicalProcessestablishment of RNA localization

NUP98 RGPD4 AGFG1 RANBP2 NUP62 NUP214 RGPD3 NUP54

3.03e-12178208GO:0051236
GeneOntologyBiologicalProcessprotein import into nucleus

NUP98 RGPD4 TARDBP RANBP2 NUP62 NUP214 RGPD3 NUP54

6.32e-12195208GO:0006606
GeneOntologyBiologicalProcessimport into nucleus

NUP98 RGPD4 TARDBP RANBP2 NUP62 NUP214 RGPD3 NUP54

8.06e-12201208GO:0051170
GeneOntologyBiologicalProcessRNA localization

NUP98 RGPD4 AGFG1 RANBP2 NUP62 NUP214 RGPD3 NUP54

1.49e-11217208GO:0006403
GeneOntologyBiologicalProcessnuclear transport

NUP98 RGPD4 AGFG1 TARDBP RANBP2 NUP62 NUP214 RGPD3 NUP54

2.98e-11378209GO:0051169
GeneOntologyBiologicalProcessnucleocytoplasmic transport

NUP98 RGPD4 AGFG1 TARDBP RANBP2 NUP62 NUP214 RGPD3 NUP54

2.98e-11378209GO:0006913
GeneOntologyBiologicalProcessnucleobase-containing compound transport

NUP98 RGPD4 AGFG1 RANBP2 NUP62 NUP214 RGPD3 NUP54

4.48e-11249208GO:0015931
GeneOntologyBiologicalProcessnuclear export

NUP98 RGPD4 AGFG1 RANBP2 NUP62 NUP214 RGPD3

2.93e-10185207GO:0051168
GeneOntologyBiologicalProcessprotein localization to nucleus

NUP98 RGPD4 TARDBP RANBP2 NUP62 NUP214 RGPD3 NUP54

8.74e-10362208GO:0034504
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD4 RANBP2 RGPD3 NUP54

3.08e-0920204GO:0006607
GeneOntologyBiologicalProcessintracellular protein transport

NUP98 RGPD4 TARDBP RANBP2 NUP62 NUP214 SNX33 RGPD3 NUP54

1.11e-08740209GO:0006886
GeneOntologyBiologicalProcessestablishment of protein localization to organelle

NUP98 RGPD4 TARDBP RANBP2 NUP62 NUP214 RGPD3 NUP54

1.38e-08515208GO:0072594
GeneOntologyBiologicalProcessintracellular transport

NUP98 RGPD4 AGFG1 TARDBP RANBP2 NUP62 NUP214 SNX33 RGPD3 NUP54 KIF3B

2.57e-0814962011GO:0046907
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RANBP2 RGPD3

6.52e-089203GO:0033133
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD4 RANBP2 RGPD3

9.31e-0810203GO:1903301
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD4 RANBP2 RGPD3

2.22e-0713203GO:0033131
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD4 RANBP2 RGPD3

2.82e-0714203GO:1903299
GeneOntologyBiologicalProcessRNA export from nucleus

NUP98 AGFG1 NUP62 NUP214

2.02e-0696204GO:0006405
GeneOntologyBiologicalProcessprotein localization to organelle

NUP98 RGPD4 TARDBP RANBP2 NUP62 NUP214 RGPD3 NUP54

4.25e-061091208GO:0033365
GeneOntologyBiologicalProcessprotein peptidyl-prolyl isomerization

RGPD4 RANBP2 RGPD3

6.44e-0638203GO:0000413
GeneOntologyBiologicalProcessregulation of nucleocytoplasmic transport

TARDBP NUP62 NUP214 NUP54

9.58e-06142204GO:0046822
GeneOntologyBiologicalProcesspeptidyl-proline modification

RGPD4 RANBP2 RGPD3

1.87e-0554203GO:0018208
GeneOntologyBiologicalProcessnucleus organization

NUP98 AGFG1 TARDBP NUP54

1.95e-05170204GO:0006997
GeneOntologyBiologicalProcessregulation of gluconeogenesis

RGPD4 RANBP2 RGPD3

4.27e-0571203GO:0006111
GeneOntologyBiologicalProcessregulation of protein import into nucleus

TARDBP NUP62 NUP54

6.34e-0581203GO:0042306
GeneOntologyBiologicalProcessmitotic centrosome separation

NUP62 KIF3B

8.07e-0514202GO:0007100
GeneOntologyBiologicalProcesscentrosome separation

NUP62 KIF3B

1.06e-0416202GO:0051299
GeneOntologyBiologicalProcessnuclear pore organization

NUP98 NUP54

1.35e-0418202GO:0006999
GeneOntologyBiologicalProcessgluconeogenesis

RGPD4 RANBP2 RGPD3

1.62e-04111203GO:0006094
GeneOntologyBiologicalProcesshexose biosynthetic process

RGPD4 RANBP2 RGPD3

1.80e-04115203GO:0019319
GeneOntologyBiologicalProcessmonosaccharide biosynthetic process

RGPD4 RANBP2 RGPD3

2.09e-04121203GO:0046364
GeneOntologyBiologicalProcessregulation of intracellular transport

TARDBP NUP62 NUP214 NUP54

2.11e-04314204GO:0032386
GeneOntologyBiologicalProcessregulation of carbohydrate biosynthetic process

RGPD4 RANBP2 RGPD3

2.70e-04132203GO:0043255
GeneOntologyBiologicalProcessregulation of glucose metabolic process

RGPD4 RANBP2 RGPD3

2.82e-04134203GO:0010906
GeneOntologyBiologicalProcessregulation of protein localization to nucleus

TARDBP NUP62 NUP54

6.26e-04176203GO:1900180
GeneOntologyBiologicalProcessregulation of intracellular protein transport

TARDBP NUP62 NUP54

6.90e-04182203GO:0033157
GeneOntologyBiologicalProcesscytokinesis

NUP62 SNX33 KIF3B

9.60e-04204203GO:0000910
GeneOntologyBiologicalProcesscytokinetic process

NUP62 SNX33

9.81e-0448202GO:0032506
GeneOntologyBiologicalProcesspositive regulation of cytokinesis

NUP62 KIF3B

1.29e-0355202GO:0032467
GeneOntologyBiologicalProcessregulation of carbohydrate metabolic process

RGPD4 RANBP2 RGPD3

1.37e-03231203GO:0006109
GeneOntologyBiologicalProcessglucose metabolic process

RGPD4 RANBP2 RGPD3

1.61e-03244203GO:0006006
GeneOntologyBiologicalProcessprotein folding

RGPD4 RANBP2 RGPD3

1.64e-03246203GO:0006457
GeneOntologyBiologicalProcesscarbohydrate biosynthetic process

RGPD4 RANBP2 RGPD3

1.66e-03247203GO:0016051
GeneOntologyBiologicalProcessprotein sumoylation

RANBP2 ZMIZ2

2.13e-0371202GO:0016925
GeneOntologyBiologicalProcessmRNA export from nucleus

AGFG1 NUP214

2.31e-0374202GO:0006406
GeneOntologyBiologicalProcesshexose metabolic process

RGPD4 RANBP2 RGPD3

2.48e-03284203GO:0019318
GeneOntologyBiologicalProcessmonosaccharide metabolic process

RGPD4 RANBP2 RGPD3

3.17e-03310203GO:0005996
GeneOntologyBiologicalProcessmitotic cytokinesis

NUP62 SNX33

3.78e-0395202GO:0000281
GeneOntologyBiologicalProcessregulation of kinase activity

RGPD4 RANBP2 NUP62 RGPD3

3.84e-03686204GO:0043549
GeneOntologyBiologicalProcessregulation of cytokinesis

NUP62 KIF3B

4.10e-0399202GO:0032465
GeneOntologyBiologicalProcesspositive regulation of cell division

NUP62 KIF3B

4.51e-03104202GO:0051781
GeneOntologyBiologicalProcessregulation of cellular localization

TARDBP NUP62 NUP214 SNX33 NUP54

5.13e-031212205GO:0060341
GeneOntologyBiologicalProcessregulation of phosphorylation

RGPD4 TARDBP RANBP2 NUP62 RGPD3

5.39e-031226205GO:0042325
GeneOntologyBiologicalProcesscytoskeleton-dependent cytokinesis

NUP62 SNX33

6.65e-03127202GO:0061640
GeneOntologyBiologicalProcesspositive regulation of kinase activity

RGPD4 RANBP2 RGPD3

6.68e-03405203GO:0033674
GeneOntologyBiologicalProcessregulation of transferase activity

RGPD4 RANBP2 NUP62 RGPD3

6.92e-03810204GO:0051338
GeneOntologyBiologicalProcesschromosome localization

NUP98 NUP62

6.95e-03130202GO:0050000
GeneOntologyBiologicalProcessregulation of small molecule metabolic process

RGPD4 RANBP2 RGPD3

8.08e-03434203GO:0062012
GeneOntologyCellularComponentnuclear pore

NUP98 RGPD4 AGFG1 RANBP2 NUP62 NUP214 RGPD3 NUP54

2.69e-14101208GO:0005643
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

NUP98 RGPD4 RANBP2 RGPD3

1.27e-1010204GO:0044614
GeneOntologyCellularComponentannulate lamellae

RGPD4 RANBP2 NUP62 RGPD3

6.06e-1014204GO:0005642
GeneOntologyCellularComponentnuclear pore nuclear basket

NUP98 RGPD4 RANBP2 RGPD3

1.85e-0918204GO:0044615
GeneOntologyCellularComponentnuclear inclusion body

NUP98 RGPD4 RANBP2 RGPD3

2.92e-0920204GO:0042405
GeneOntologyCellularComponentnuclear envelope

NUP98 RGPD4 AGFG1 RANBP2 NUP62 NUP214 RGPD3 NUP54

2.39e-08560208GO:0005635
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RANBP2 RGPD3

4.18e-088203GO:1990723
GeneOntologyCellularComponentnuclear membrane

NUP98 RGPD4 RANBP2 NUP62 RGPD3 NUP54

6.60e-07349206GO:0031965
GeneOntologyCellularComponentSUMO ligase complex

RGPD4 RANBP2 RGPD3

9.85e-0721203GO:0106068
GeneOntologyCellularComponentinclusion body

NUP98 RGPD4 RANBP2 RGPD3

1.48e-0690204GO:0016234
GeneOntologyCellularComponentnuclear pore central transport channel

NUP62 NUP54

1.82e-057202GO:0044613
GeneOntologyCellularComponentnuclear protein-containing complex

NUP98 RGPD4 AGFG1 RANBP2 NUP62 NUP214 RGPD3 NUP54

2.14e-051377208GO:0140513
GeneOntologyCellularComponentorganelle envelope

NUP98 RGPD4 AGFG1 RANBP2 NUP62 NUP214 RGPD3 NUP54

2.89e-051435208GO:0031967
GeneOntologyCellularComponentmidbody

NUP62 SCCPDH KIF3B

1.18e-03222203GO:0030496
GeneOntologyCellularComponenttertiary granule lumen

OLFM4 FLG2

1.25e-0355202GO:1904724
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

RGPD4 RANBP2 NUP62 SARAF RGPD3

7.11e-031327205GO:0042175
GeneOntologyCellularComponenttertiary granule

OLFM4 FLG2

1.06e-02164202GO:0070820
GeneOntologyCellularComponentperinuclear region of cytoplasm

RGPD4 OLFM4 RANBP2 RGPD3

1.08e-02934204GO:0048471
HumanPhenoGliosis

TARDBP RANBP2 NUP62 NUP54

1.63e-0510094HP:0002171
HumanPhenoAbnormal corpus striatum morphology

RANBP2 NUP62 NUP54

4.54e-054393HP:0010994
HumanPhenoStructural abnormalities in the basal ganglia

NUP62 NUP54

7.73e-05892HP:0006952
HumanPhenoHorizontal pendular nystagmus

NUP62 NUP54

7.73e-05892HP:0007811
HumanPhenoBasal ganglia cysts

NUP62 NUP54

7.73e-05892HP:0006799
HumanPhenoUpper limb muscle weakness

KY TARDBP NUP62 NUP54

8.33e-0515194HP:0003484
HumanPhenoTetraplegia/tetraparesis

TARDBP RANBP2 NUP62 NUP54

8.33e-0515194HP:0030182
HumanPhenoBasal ganglia gliosis

NUP62 NUP54

1.51e-041192HP:0006999
HumanPhenoAbnormal glial cell morphology

TARDBP RANBP2 NUP62 NUP54

1.92e-0418794HP:0100705
HumanPhenoUndetectable light- and dark-adapted electroretinogram

NUP62 NUP54

2.50e-041492HP:0007688
HumanPhenoSmall basal ganglia

NUP62 NUP54

2.50e-041492HP:0012697
HumanPhenoAbnormal full-field electroretinogram

NUP62 NUP54 KIF3B

3.15e-048293HP:0030466
HumanPhenoAppendicular spasticity

KY TARDBP RANBP2 NUP62 NUP54

4.19e-0443595HP:0034353
HumanPhenoAtrophy/Degeneration involving the caudate nucleus

NUP62 NUP54

4.67e-041992HP:0007374
HumanPhenoCongenital nystagmus

NUP62 NUP54

6.29e-042292HP:0006934
HumanPhenoAstrocytosis

NUP62 NUP54

6.29e-042292HP:0002446
HumanPhenoHypertonia

KY TARDBP RANBP2 NUP62 NUP214 NUP54 TCF20

6.89e-04115197HP:0001276
HumanPhenoSpasticity

KY TARDBP RANBP2 NUP62 NUP214 NUP54 TCF20

6.89e-04115197HP:0001257
HumanPhenoAbnormal caudate nucleus morphology

NUP62 NUP54

8.15e-042592HP:0002339
HumanPhenoTetraparesis

TARDBP NUP62 NUP54

8.97e-0411793HP:0002273
HumanPhenoBabinski sign

KY TARDBP NUP62 NUP54

1.19e-0330194HP:0003487
HumanPhenoAbnormal superficial reflex

KY TARDBP NUP62 NUP54

1.19e-0330194HP:0031828
HumanPhenoWeakness due to upper motor neuron dysfunction

KY TARDBP RANBP2 NUP62 NUP54

1.26e-0355195HP:0010549
HumanPhenoCogwheel rigidity

NUP62 NUP54

1.34e-033292HP:0002396
HumanPhenoAbnormal light- and dark-adapted electroretinogram

NUP62 NUP54

1.99e-033992HP:0008323
HumanPhenoLimb muscle weakness

KY TARDBP NUP62 NUP54

2.30e-0335994HP:0003690
MousePhenoelevated level of mitotic sister chromatid exchange

RGPD4 RANBP2 RGPD3

9.93e-0716183MP:0003701
MousePhenoabnormal morula morphology

RGPD4 RANBP2 RGPD3

4.58e-0626183MP:0012058
MousePhenodecreased tumor latency

RGPD4 RANBP2 RGPD3

7.12e-0630183MP:0010308
MousePhenofailure of blastocyst formation

RGPD4 RANBP2 RGPD3

7.88e-0631183MP:0012129
MousePhenoabnormal tumor latency

RGPD4 RANBP2 RGPD3

1.05e-0534183MP:0010307
MousePhenoabnormal blastocyst formation

RGPD4 RANBP2 RGPD3

1.59e-0539183MP:0012128
MousePhenoembryonic lethality prior to organogenesis, complete penetrance

RGPD4 TARDBP RANBP2 NUP62 NUP214 RGPD3 NUP54

2.84e-05772187MP:0014259
MousePhenoembryonic lethality prior to tooth bud stage, complete penetrance

RGPD4 TARDBP RANBP2 NUP62 NUP214 RGPD3 NUP54

3.01e-05779187MP:0014257
MousePhenoembryonic lethality prior to organogenesis

RGPD4 TARDBP RANBP2 NUP62 ZMIZ2 NUP214 RGPD3 NUP54

5.90e-051204188MP:0013292
MousePhenoaneuploidy

RGPD4 RANBP2 RGPD3

6.16e-0561183MP:0004024
MousePhenoincreased hepatocellular carcinoma incidence

RGPD4 RANBP2 RGPD3

9.30e-0570183MP:0003331
MousePhenoembryonic lethality before implantation, complete penetrance

RGPD4 RANBP2 NUP214 RGPD3

1.13e-04203184MP:0011094
MousePhenoincreased lung carcinoma incidence

RGPD4 RANBP2 RGPD3

1.28e-0478183MP:0008714
MousePhenoembryonic lethality prior to tooth bud stage

RGPD4 TARDBP RANBP2 NUP62 ZMIZ2 NUP214 RGPD3 NUP54

1.59e-041383188MP:0013293
MousePhenoabnormal chromosome number

RGPD4 RANBP2 RGPD3

1.72e-0486183MP:0004023
MousePhenoembryonic lethality before implantation

RGPD4 RANBP2 NUP214 RGPD3

2.21e-04242184MP:0006204
MousePhenoenlarged epididymis

RGPD4 RANBP2 RGPD3

2.60e-0499183MP:0004931
MousePhenoincreased sarcoma incidence

RGPD4 RANBP2 RGPD3

2.84e-04102183MP:0002032
MousePhenofailure of blastocyst to hatch from the zona pellucida

RGPD4 RANBP2 RGPD3

3.27e-04107183MP:0003694
MousePhenoincreased lung tumor incidence

RGPD4 RANBP2 RGPD3

3.27e-04107183MP:0008014
MousePhenoincreased respiratory system tumor incidence

RGPD4 RANBP2 RGPD3

3.27e-04107183MP:0010298
MousePhenoincreased liver tumor incidence

RGPD4 RANBP2 RGPD3

3.65e-04111183MP:0008019
MousePhenoincreased hepatobiliary system tumor incidence

RGPD4 RANBP2 RGPD3

3.65e-04111183MP:0010297
MousePhenoabnormal blastocyst hatching

RGPD4 RANBP2 RGPD3

3.84e-04113183MP:0003693
MousePhenoabnormal preimplantation embryo morphology

RGPD4 RANBP2 NUP214 RGPD3

4.02e-04283184MP:0014137
MousePhenoabnormal rod electrophysiology

RGPD4 RANBP2 RGPD3

4.47e-04119183MP:0004021
MousePhenoabnormal chromosome morphology

RGPD4 RANBP2 RGPD3

5.28e-04126183MP:0003702
MousePhenoabnormal mitosis

RGPD4 RANBP2 RGPD3

5.53e-04128183MP:0004046
MousePhenoincreased incidence of tumors by chemical induction

RGPD4 RANBP2 RGPD3

7.34e-04141183MP:0004499
MousePhenodecreased susceptibility to diet-induced obesity

RGPD4 RANBP2 RGPD3

1.06e-03160183MP:0005659
MousePhenoabnormal epididymis size

RGPD4 RANBP2 RGPD3

1.18e-03166183MP:0004926
MousePhenoabnormal preimplantation embryo development

RGPD4 RANBP2 RGPD3

1.28e-03171183MP:0009781
MousePhenoincreased incidence of induced tumors

RGPD4 RANBP2 RGPD3

1.33e-03173183MP:0002021
MousePhenoabnormal cell nucleus morphology

RGPD4 RANBP2 RGPD3

1.58e-03184183MP:0003111
MousePhenodecreased susceptibility to weight gain

RGPD4 RANBP2 RGPD3

1.63e-03186183MP:0010182
MousePhenoincreased energy expenditure

RGPD4 RANBP2 RGPD3

1.90e-03196183MP:0004889
MousePhenoincreased carcinoma incidence

RGPD4 RANBP2 RGPD3

1.92e-03197183MP:0002038
MousePhenoincreased stereotypic behavior

KIF3B TCF20

2.08e-0353182MP:0001409
MousePhenostereotypic behavior

TARDBP KIF3B TCF20

2.44e-03214183MP:0001408
MousePhenoabnormal eye electrophysiology

RGPD4 RANBP2 RGPD3

2.92e-03228183MP:0005551
MousePhenoincreased malignant tumor incidence

RGPD4 RANBP2 RGPD3

3.25e-03237183MP:0002018
MousePhenoabnormal vocalization

SNX33 SCCPDH TCF20

3.25e-03237183MP:0001529
MousePhenoabnormal cell cycle

RGPD4 TARDBP RANBP2 RGPD3

3.82e-03520184MP:0003077
MousePhenoabnormal intracellular organelle morphology

RGPD4 TARDBP RANBP2 RGPD3

4.55e-03546184MP:0014239
MousePhenoabnormal incidence of induced tumors

RGPD4 RANBP2 RGPD3

4.64e-03269183MP:0013151
MousePhenoabnormal epididymis morphology

RGPD4 RANBP2 RGPD3

4.64e-03269183MP:0002631
DomainRan_BP1

RGPD4 RANBP2 RGPD3

2.30e-0712203PF00638
DomainRANBD1

RGPD4 RANBP2 RGPD3

2.30e-0712203PS50196
DomainRanBD

RGPD4 RANBP2 RGPD3

2.98e-0713203SM00160
DomainRan_bind_dom

RGPD4 RANBP2 RGPD3

2.98e-0713203IPR000156
DomainGCC2_Rab_bind

RGPD4 RGPD3

2.28e-057202IPR032023
DomainRab_bind

RGPD4 RGPD3

2.28e-057202PF16704
Domain-

RGPD4 RGPD3

4.88e-05102021.10.220.60
DomainGrip

RGPD4 RGPD3

5.96e-0511202SM00755
DomainGRIP

RGPD4 RGPD3

5.96e-0511202PF01465
DomainGRIP_dom

RGPD4 RGPD3

7.14e-0512202IPR000237
DomainGRIP

RGPD4 RGPD3

7.14e-0512202PS50913
DomainTPR

RGPD4 RANBP2 RGPD3

3.37e-04129203SM00028
DomainTPR_repeat

RGPD4 RANBP2 RGPD3

3.68e-04133203IPR019734
DomainArfGap

AGFG1 AGFG2

4.35e-0429202SM00105
DomainArfGAP

AGFG1 AGFG2

4.35e-0429202IPR001164
DomainArfGap

AGFG1 AGFG2

4.35e-0429202PF01412
DomainARFGAP

AGFG1 AGFG2

4.35e-0429202PS50115
DomainTPR-contain_dom

RGPD4 RANBP2 RGPD3

5.24e-04150203IPR013026
DomainTPR

RGPD4 RANBP2 RGPD3

6.91e-04165203PS50005
DomainTPR_REGION

RGPD4 RANBP2 RGPD3

6.91e-04165203PS50293
Domain-

RGPD4 RANBP2 RGPD3

1.33e-032072031.25.40.10
DomainTPR-like_helical_dom

RGPD4 RANBP2 RGPD3

1.87e-03233203IPR011990
Domain-

RGPD4 RANBP2 RGPD3

7.97e-033912032.30.29.30
DomainPH_dom-like

RGPD4 RANBP2 RGPD3

1.01e-02426203IPR011993
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

2.65e-1440187MM14945
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

3.19e-1441187MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

3.82e-1442187MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

4.56e-1443187MM14609
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

8.88e-1447187MM14939
PathwayREACTOME_GENE_SILENCING_BY_RNA

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

1.21e-1349187MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

1.41e-1350187MM14610
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

1.63e-1351187MM15151
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

2.85e-1355187MM14917
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

4.22e-1358187MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

4.22e-1358187MM14736
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

9.71e-1365187MM15147
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

2.26e-1273187MM14948
PathwayREACTOME_GLUCOSE_METABOLISM

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

5.24e-1282187MM15394
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

6.24e-1284187MM14929
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

7.39e-1286187MM15413
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

1.20e-1192187MM14951
PathwayREACTOME_MITOTIC_PROPHASE

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

5.55e-11114187MM15361
PathwayREACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN

NUP98 RANBP2 NUP62 NUP214 NUP54

3.65e-1032185M29579
PathwayREACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS

NUP98 RANBP2 NUP62 NUP214 NUP54

4.29e-1033185M27016
PathwayREACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN

NUP98 RANBP2 NUP62 NUP214 NUP54

5.03e-1034185M27041
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

NUP98 RANBP2 NUP62 NUP214 NUP54

5.86e-1035185M27320
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

NUP98 RANBP2 NUP62 NUP214 NUP54

6.80e-1036185M26974
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

NUP98 RANBP2 NUP62 NUP214 NUP54

6.80e-1036185M27245
PathwayREACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS

NUP98 RANBP2 NUP62 NUP214 NUP54

7.86e-1037185M1029
PathwayREACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS

NUP98 RANBP2 NUP62 NUP214 NUP54

7.86e-1037185M27038
PathwayREACTOME_SUMOYLATION

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

8.95e-10169187MM14919
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

NUP98 RANBP2 NUP62 NUP214 NUP54

1.04e-0939185M27238
PathwayREACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS

NUP98 RANBP2 NUP62 NUP214 NUP54

1.35e-0941185M29574
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

NUP98 RANBP2 NUP62 NUP214 NUP54

1.73e-0943185M26975
PathwayREACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS

NUP98 RANBP2 NUP62 NUP214 NUP54

1.95e-0944185M109
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

NUP98 RANBP2 NUP62 NUP214 NUP54

2.45e-0946185M27397
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

NUP98 RANBP2 NUP62 NUP214 NUP54

2.74e-0947185M27395
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

NUP98 RANBP2 NUP62 NUP214 NUP54

5.11e-0953185M27212
PathwayREACTOME_SNRNP_ASSEMBLY

NUP98 RANBP2 NUP62 NUP214 NUP54

5.63e-0954185M29594
PathwayREACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS

NUP98 RANBP2 NUP62 NUP214 NUP54

8.88e-0959185M27606
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

NUP98 RANBP2 NUP62 NUP214 NUP54

2.29e-0871185M27394
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

2.38e-08271187MM15406
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

2.77e-08277187MM15414
PathwayREACTOME_ISG15_ANTIVIRAL_MECHANISM

NUP98 RANBP2 NUP62 NUP214 NUP54

2.82e-0874185M48006
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

NUP98 RANBP2 NUP62 NUP214 NUP54

3.45e-0877185M27226
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

NUP98 RANBP2 NUP62 NUP214 NUP54

4.75e-0882185M27250
PathwayKEGG_MEDICUS_REFERENCE_NUCLEAR_EXPORT_OF_MRNA

RANBP2 NUP62 NUP214 NUP54

4.99e-0830184M47752
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

NUP98 RANBP2 NUP62 NUP214 NUP54

5.37e-0884185M725
PathwayREACTOME_GLUCOSE_METABOLISM

NUP98 RANBP2 NUP62 NUP214 NUP54

5.70e-0885185M1870
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

NUP98 RANBP2 NUP62 NUP214 NUP54

1.23e-0799185M27474
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

NUP98 RANBP2 NUP62 NUP214 NUP54

1.36e-07101185M27253
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

NUP98 RANBP2 NUP62 NUP214 NUP54

1.73e-07106185M27458
PathwayWP_PRADERWILLI_AND_ANGELMAN_SYNDROME

NUP98 RANBP2 NUP62 NUP214 NUP54

1.99e-07109185M39542
PathwayREACTOME_TRNA_PROCESSING

NUP98 RANBP2 NUP62 NUP214 NUP54

2.18e-07111185M27684
PathwayREACTOME_HCMV_LATE_EVENTS

NUP98 RANBP2 NUP62 NUP214 NUP54

2.72e-07116185M29806
PathwayREACTOME_M_PHASE

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

2.73e-07387187MM15364
PathwayBIOCARTA_NPC_PATHWAY

RANBP2 NUP62 NUP214

2.87e-0711183M22033
PathwayREACTOME_SARS_COV_2_ACTIVATES_MODULATES_INNATE_AND_ADAPTIVE_IMMUNE_RESPONSES

NUP98 RANBP2 NUP62 NUP214 NUP54

4.11e-07126185M45009
PathwayREACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS

NUP98 RANBP2 NUP62 NUP214 NUP54

4.99e-07131185M5283
PathwayREACTOME_HCMV_EARLY_EVENTS

NUP98 RANBP2 NUP62 NUP214 NUP54

6.47e-07138185M29805
PathwayREACTOME_GENE_SILENCING_BY_RNA

NUP98 RANBP2 NUP62 NUP214 NUP54

6.70e-07139185M715
PathwayREACTOME_MITOTIC_PROPHASE

NUP98 RANBP2 NUP62 NUP214 NUP54

7.45e-07142185M27660
PathwayREACTOME_HIV_LIFE_CYCLE

NUP98 RANBP2 NUP62 NUP214 NUP54

9.46e-07149185M4076
PathwayREACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES

NUP98 RANBP2 NUP62 NUP214 NUP54

1.01e-06151185M550
PathwayREACTOME_INFLUENZA_INFECTION

NUP98 RANBP2 NUP62 NUP214 NUP54

1.23e-06157185M4669
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 RANBP2 RGPD3

1.41e-0618183MM1549
PathwayREACTOME_HCMV_INFECTION

NUP98 RANBP2 NUP62 NUP214 NUP54

1.43e-06162185M29804
PathwayREACTOME_CELLULAR_RESPONSES_TO_STIMULI

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

1.64e-06505187MM15548
PathwayREACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS

NUP98 RANBP2 NUP62 NUP214 NUP54

2.21e-06177185M27476
PathwayREACTOME_SUMOYLATION

NUP98 RANBP2 NUP62 NUP214 NUP54

3.06e-06189185M27214
PathwayREACTOME_SARS_COV_2_HOST_INTERACTIONS

NUP98 RANBP2 NUP62 NUP214 NUP54

4.44e-06204185M45011
PathwayREACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION

NUP98 NUP62 NUP54

5.02e-0627183M29807
PathwayREACTOME_CELL_CYCLE

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

5.33e-06603187MM14635
PathwayREACTOME_METABOLISM_OF_RNA

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

5.88e-06612187MM15547
PathwayREACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES

NUP98 RGPD4 RANBP2 RGPD3

6.76e-06100184MM14561
PathwayREACTOME_HIV_INFECTION

NUP98 RANBP2 NUP62 NUP214 NUP54

8.14e-06231185M12469
PathwayREACTOME_MITOTIC_SPINDLE_CHECKPOINT

NUP98 RGPD4 RANBP2 RGPD3

1.26e-05117184MM15387
PathwayREACTOME_INTERFERON_SIGNALING

NUP98 RANBP2 NUP62 NUP214 NUP54

1.83e-05273185M983
PathwayREACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION

NUP98 RGPD4 RANBP2 RGPD3

1.85e-05129184MM14894
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

NUP98 RANBP2 NUP62 NUP214 NUP54

2.18e-05283185M13087
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

NUP98 RANBP2 NUP62 NUP214 NUP54

2.37e-05288185M16864
PathwayREACTOME_RHO_GTPASES_ACTIVATE_FORMINS

NUP98 RGPD4 RANBP2 RGPD3

2.63e-05141184MM15266
PathwayREACTOME_SARS_COV_2_INFECTION

NUP98 RANBP2 NUP62 NUP214 NUP54

2.84e-05299185M41727
PathwayREACTOME_SEPARATION_OF_SISTER_CHROMATIDS

NUP98 RGPD4 RANBP2 RGPD3

8.97e-05193184MM14890
PathwayREACTOME_MITOTIC_PROMETAPHASE

NUP98 RGPD4 RANBP2 RGPD3

1.07e-04202184MM15362
PathwayREACTOME_NUCLEAR_ENVELOPE_NE_REASSEMBLY

NUP98 NUP62 NUP54

1.16e-0476183M27215
PathwayREACTOME_M_PHASE

NUP98 RANBP2 NUP62 NUP214 NUP54

1.38e-04417185M27662
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

1.61e-041022187MM15436
PathwayREACTOME_MITOTIC_METAPHASE_AND_ANAPHASE

NUP98 RGPD4 RANBP2 RGPD3

1.89e-04234184MM14898
PathwayREACTOME_MITOTIC_METAPHASE_AND_ANAPHASE

NUP98 RANBP2 NUP62 NUP54

1.95e-04236184M27185
PathwayREACTOME_SARS_COV_INFECTIONS

NUP98 RANBP2 NUP62 NUP214 NUP54

2.43e-04471185M39009
PathwayREACTOME_RHO_GTPASE_EFFECTORS

NUP98 RGPD4 RANBP2 RGPD3

2.70e-04257184MM14755
PathwayREACTOME_CELL_CYCLE_CHECKPOINTS

NUP98 RGPD4 RANBP2 RGPD3

3.30e-04271184MM15388
PathwayREACTOME_CELL_CYCLE_MITOTIC

NUP98 RANBP2 NUP62 NUP214 NUP54

5.46e-04561185M5336
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

1.06e-031389187MM15307
PathwayREACTOME_CELL_CYCLE

NUP98 RANBP2 NUP62 NUP214 NUP54

1.43e-03694185M543
PathwayREACTOME_METABOLISM_OF_RNA

NUP98 RANBP2 NUP62 NUP214 NUP54

1.73e-03724185M16843
PathwayREACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM

NUP98 RANBP2 NUP62 NUP214 NUP54

2.52e-03789185M1060
PathwayREACTOME_CELLULAR_RESPONSES_TO_STIMULI

NUP98 RANBP2 NUP62 NUP214 NUP54

3.11e-03828185M27827
PathwayREACTOME_VIRAL_INFECTION_PATHWAYS

NUP98 RANBP2 NUP62 NUP214 NUP54

4.22e-03888185M48034
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

NUP98 RGPD4 RANBP2 RGPD3

8.13e-03649184MM15690
PathwayREACTOME_MITOTIC_SPINDLE_CHECKPOINT

NUP98 RANBP2

8.66e-03111182M27673
PathwayREACTOME_INFECTIOUS_DISEASE

NUP98 RANBP2 NUP62 NUP214 NUP54

9.68e-031081185M27548
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

7.94e-173820712791264
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RGPD4 RANBP2 NUP62 NUP214 RGPD3

1.09e-131520514697343
Pubmed

Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1.

NUP98 RANBP2 NUP62 NUP214

3.97e-13520419828735
Pubmed

Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase.

NUP98 RANBP2 NUP62 NUP214 NUP54

1.93e-122520510601273
Pubmed

Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.

NUP98 RANBP2 NUP62 NUP214 NUP54

2.39e-122620512228227
Pubmed

Imaging within single NPCs reveals NXF1's role in mRNA export on the cytoplasmic side of the pore.

NUP98 RANBP2 NUP62 NUP214

5.56e-12820431375530
Pubmed

Cloning and characterization of human karyopherin beta3.

NUP98 RANBP2 NUP62 NUP214

1.00e-1192049114010
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD4 RANBP2 RGPD3 KIF3B

1.00e-1192049733766
Pubmed

Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure.

NUP98 RANBP2 NUP62 NUP214 NUP54

2.38e-114020537516964
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

NUP98 RGPD4 RANBP2 RGPD3

5.66e-111320431427429
Pubmed

A role for nucleoporin FG repeat domains in export of human immunodeficiency virus type 1 Rev protein and RNA from the nucleus.

NUP98 AGFG1 NUP214

1.63e-1032038943370
Pubmed

The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates.

NUP98 RANBP2 NUP62 NUP214

1.88e-101720410668806
Pubmed

The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export.

NUP98 AGFG1 NUP214

6.50e-1042039368759
Pubmed

Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence.

NUP98 NUP62 NUP214

6.50e-10420330543681
Pubmed

Interaction network of human early embryonic transcription factors.

NUP98 RANBP2 ZMIZ2 NUP214 NUP54 TCF20 FLG2

6.96e-1035120738297188
Pubmed

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

NUP98 RANBP2 NUP62 NUP214 NUP54

7.04e-107720524927568
Pubmed

The nuclear pore complex: from molecular architecture to functional dynamics.

NUP62 NUP214 NUP54

1.62e-09520310395558
Pubmed

Mutations in tap uncouple RNA export activity from translocation through the nuclear pore complex.

NUP98 RANBP2 NUP62

1.62e-09520316314397
Pubmed

The N-terminal domain of the mammalian nucleoporin p62 interacts with other nucleoporins of the FXFG family during interphase.

RANBP2 NUP62 NUP214

1.62e-09520316730000
Pubmed

The Structure Inventory of the Nuclear Pore Complex.

RANBP2 NUP62 NUP214 NUP54

2.16e-093020427016207
Pubmed

Integrated structural analysis of the human nuclear pore complex scaffold.

RANBP2 NUP62 NUP214 NUP54

2.16e-093020424315095
Pubmed

Karyopherin beta2 mediates nuclear import of a mRNA binding protein.

NUP98 RANBP2 NUP214

3.25e-0962039144189
Pubmed

Cessation of HIV-1 transcription by inhibiting regulatory protein Rev-mediated RNA transport.

NUP98 AGFG1 NUP214

3.25e-09620319149559
Pubmed

Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import.

RANBP2 NUP62 NUP54

3.25e-09620311266456
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

NUP98 AGFG2 NUP62 NUP214 RGPD3 NUP54 TCF20

4.32e-0945720732344865
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD4 RANBP2 RGPD3

5.68e-0972037559465
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD4 RANBP2 RGPD3

5.68e-09720330944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD4 RANBP2 RGPD3

5.68e-09720338838144
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RANBP2 RGPD3

5.68e-09720321205196
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RANBP2 RGPD3

5.68e-09720326632511
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD4 RANBP2 RGPD3

5.68e-09720317372272
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RANBP2 RGPD3

5.68e-09720324403063
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RANBP2 RGPD3

5.68e-09720318949001
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RANBP2 RGPD3

5.68e-09720323818861
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD4 RANBP2 RGPD3

5.68e-09720338657106
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RANBP2 RGPD3

5.68e-09720311353387
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RANBP2 RGPD3

5.68e-09720325187515
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RANBP2 RGPD3

5.68e-0972039037092
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD4 RANBP2 RGPD3

5.68e-09720323536549
Pubmed

Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins.

NUP98 NUP62 NUP54

5.68e-0972038707840
Pubmed

Cofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin.

NUP98 NUP62 NUP214

5.68e-09720311238447
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD4 RANBP2 RGPD3

5.68e-09720312191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD4 RANBP2 RGPD3

5.68e-09720322821000
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RANBP2 RGPD3

5.68e-0972038603673
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD4 RANBP2 RGPD3

5.68e-09720320682751
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

NUP98 RANBP2 NUP62 NUP214 TCF20

7.57e-0912320526912792
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD4 RANBP2 RGPD3

9.09e-09820322262462
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD4 RANBP2 RGPD3

9.09e-09820321670213
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD4 RANBP2 RGPD3

9.09e-09820328745977
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD4 RANBP2 RGPD3

9.09e-09820327412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD4 RANBP2 RGPD3

9.09e-09820321310149
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RANBP2 RGPD3

1.36e-08920318394993
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD4 RANBP2 RGPD3

1.36e-08920328877029
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD4 RANBP2 RGPD3

1.36e-08920311553612
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD4 RANBP2 RGPD3

1.36e-08920317887960
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD4 RANBP2 RGPD3

1.36e-08920310601307
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD4 RANBP2 RGPD3

1.36e-08920328100513
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD4 RANBP2 RGPD3

1.95e-081020316332688
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD4 RANBP2 RGPD3

1.95e-081020327160050
Pubmed

Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta.

NUP98 NUP62 NUP214

1.95e-081020319581287
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD4 RANBP2 RGPD3

1.95e-08102038857542
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD4 RANBP2 RGPD3

1.95e-081020321859863
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RGPD4 RANBP2 RGPD3

2.68e-081120335771867
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RGPD4 RANBP2 RGPD3

2.68e-081120317069463
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD4 RANBP2 RGPD3

2.68e-081120334110283
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NUP98 RGPD4 TARDBP RANBP2 TRO NUP62 RGPD3 SCCPDH NUP54

3.92e-08144220935575683
Pubmed

TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.

NUP98 NUP62 NUP214

5.90e-081420311073998
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RGPD4 RANBP2 ZMIZ2 NUP214 RGPD3 TCF20

9.77e-0841820634709266
Pubmed

Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.

NUP98 RGPD4 RANBP2 RGPD3 SCCPDH

1.59e-0722620537839992
Pubmed

A human MAP kinase interactome.

NUP98 AGFG1 RANBP2 NUP214 NUP54 TCF20

2.37e-0748620620936779
Pubmed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

RGPD4 RANBP2 RGPD3

2.49e-072220327717094
Pubmed

Nuclear distributions of NUP62 and NUP214 suggest architectural diversity and spatial patterning among nuclear pore complexes.

NUP62 NUP214

3.14e-07220222558357
Pubmed

Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex.

NUP62 NUP54

3.14e-0722028589458
Pubmed

HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2.

NUP98 RANBP2

3.14e-07220221423673
Pubmed

Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.

NUP98 RANBP2 NUP62 NUP214 TCF20

4.83e-0728320518854154
Pubmed

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

NUP98 NUP62 NUP214 SCCPDH NUP54

6.23e-0729820532353859
Pubmed

Human transcription factor protein interaction networks.

NUP98 TARDBP NUP62 ZMIZ2 NUP214 NUP54 TCF20 FLG2

6.45e-07142920835140242
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

NUP98 AGFG1 TARDBP RANBP2 NUP62 NUP214 TCF20

6.48e-0795420736373674
Pubmed

Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexes.

NUP98 NUP214

9.42e-07320212589057
Pubmed

Functional analysis of the interaction of the human immunodeficiency virus type 1 Rev nuclear export signal with its cofactors.

NUP98 AGFG1

9.42e-07320214554087
Pubmed

The nuclear pore complex: a new dynamic in HIV-1 replication.

NUP98 NUP214

9.42e-07320221327100
Pubmed

Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 Rev.

NUP98 NUP214

9.42e-0732029847314
Pubmed

Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathways.

NUP98 NUP62

9.42e-07320222334672
Pubmed

Interactions and three-dimensional localization of a group of nuclear pore complex proteins.

NUP62 NUP54

9.42e-0732028045926
Pubmed

Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo.

NUP98 NUP62 NUP214

9.62e-073420318539113
Pubmed

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.

NUP98 RGPD4 RANBP2 RGPD3

1.00e-0613520431077711
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

NUP98 TARDBP RANBP2 NUP62 NUP214 NUP54 TCF20

1.04e-06102420724711643
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

NUP98 NUP62 NUP214 RGPD3 NUP54

1.06e-0633220525693804
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

NUP98 RANBP2 NUP62 NUP214 NUP54 FLG2

1.41e-0666020632780723
Pubmed

A new nucleoporin-like protein interacts with both HIV-1 Rev nuclear export signal and CRM-1.

AGFG1 NUP214

1.88e-06420210358091
Pubmed

Trans-repressive effect of NUP98-PMX1 on PMX1-regulated c-FOS gene through recruitment of histone deacetylase 1 by FG repeats.

NUP98 NUP54

1.88e-06420216651408
Pubmed

In vitro analysis of nuclear transport mediated by the C-terminal shuttle domain of Tap.

NUP98 NUP214

1.88e-06420211551912
Pubmed

Tpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein export.

NUP98 RANBP2

1.88e-06420211839768
Pubmed

Two closely related human nuclear export factors utilize entirely distinct export pathways.

AGFG1 NUP214

1.88e-06420211545741
Pubmed

Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization.

AGFG1 AGFG2

1.88e-0642029446614
Pubmed

Karyopherin-centric control of nuclear pores based on molecular occupancy and kinetic analysis of multivalent binding with FG nucleoporins.

NUP98 NUP62

1.88e-06420224739174
Pubmed

Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly.

NUP98 NUP62

1.88e-0642029348540
Pubmed

The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport.

AGFG1 AGFG2

1.88e-06420210613896
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

NUP98 RGPD4 TARDBP RANBP2 NUP62 NUP214 RGPD3

2.32e-06115520720360068
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

NUP98 TARDBP RANBP2 NUP62 NUP54

3.01e-0641120535182466
InteractionRANBP1 interactions

NUP98 TARDBP RANBP2 NUP62 NUP214 RGPD3 NUP54

8.62e-10211207int:RANBP1
InteractionNUP35 interactions

NUP98 AGFG2 RANBP2 NUP62 NUP214 RGPD3 NUP54 TCF20

3.63e-09424208int:NUP35
InteractionDPPA3 interactions

NUP98 RANBP2 NUP62 NUP214 NUP54

5.20e-0967205int:DPPA3
InteractionCLIP1 interactions

NUP98 RANBP2 NUP62 NUP214 RGPD3 NUP54

1.80e-08183206int:CLIP1
InteractionNUP58 interactions

NUP98 RANBP2 NUP62 NUP214 NUP54

2.61e-0892205int:NUP58
InteractionRANBP2 interactions

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 KIF3B

3.54e-08361207int:RANBP2
InteractionNUTF2 interactions

NUP98 RANBP2 NUP62 NUP214 NUP54

9.94e-08120205int:NUTF2
InteractionRGPD3 interactions

RGPD4 RANBP2 NUP62 RGPD3

1.22e-0747204int:RGPD3
InteractionRGPD1 interactions

NUP98 RGPD4 RANBP2 RGPD3

1.45e-0749204int:RGPD1
InteractionNUP62 interactions

NUP98 RANBP2 NUP62 NUP214 RGPD3 NUP54

1.93e-07273206int:NUP62
InteractionRAN interactions

NUP98 RGPD4 RANBP2 NUP62 NUP214 RGPD3 NUP54

2.30e-07475207int:RAN
InteractionRGPD8 interactions

RGPD4 RANBP2 NUP62 RGPD3

7.76e-0774204int:RGPD8
InteractionNUP214 interactions

NUP98 RANBP2 NUP62 NUP214 NUP54

1.11e-06195205int:NUP214
InteractionRGPD4 interactions

RGPD4 RANBP2 RGPD3

1.27e-0622203int:RGPD4
InteractionNUP153 interactions

NUP98 RANBP2 NUP62 NUP214 NUP54

1.84e-06216205int:NUP153
InteractionNUP98 interactions

NUP98 RANBP2 NUP62 NUP214 NUP54

2.01e-06220205int:NUP98
InteractionNUP107 interactions

NUP98 RANBP2 NUP62 NUP214 NUP54

2.05e-06221205int:NUP107
InteractionRGPD5 interactions

RGPD4 RANBP2 NUP62 RGPD3

2.21e-0696204int:RGPD5
InteractionRGPD2 interactions

RGPD4 RANBP2 RGPD3

2.41e-0627203int:RGPD2
InteractionNUP205 interactions

NUP98 RANBP2 NUP62 NUP214 NUP54

2.78e-06235205int:NUP205
InteractionRAE1 interactions

NUP98 RANBP2 NUP62 NUP214 NUP54

2.84e-06236205int:RAE1
InteractionETV6 interactions

NUP98 NUP62 NUP214 NUP54

3.16e-06105204int:ETV6
InteractionCEBPB interactions

NUP98 RGPD4 AGFG1 TARDBP RANBP2 NUP62 NUP214 SCCPDH TCF20

3.93e-061443209int:CEBPB
InteractionNUMA1 interactions

NUP98 RANBP2 NUP62 NUP214 RGPD3 NUP54

4.52e-06469206int:NUMA1
InteractionNUP54 interactions

NUP98 NUP62 NUP214 NUP54

8.84e-06136204int:NUP54
InteractionG3BP1 interactions

NUP98 TARDBP RANBP2 NUP62 NUP214 RGPD3 NUP54

9.87e-06835207int:G3BP1
InteractionNUP88 interactions

NUP98 RANBP2 NUP62 NUP214

9.91e-06140204int:NUP88
InteractionIFT20 interactions

NUP62 SCCPDH NUP54 KIF3B

1.08e-05143204int:IFT20
InteractionGLE1 interactions

NUP98 NUP62 NUP214 NUP54

1.30e-05150204int:GLE1
InteractionSLX4 interactions

TARDBP RANBP2 ZMIZ2 NUP214 RGPD3 TCF20

1.41e-05572206int:SLX4
InteractionNUP85 interactions

NUP98 RANBP2 NUP62 NUP214

1.52e-05156204int:NUP85
InteractionSEH1L interactions

NUP98 RANBP2 NUP62 NUP214

1.60e-05158204int:SEH1L
InteractionRPS6KL1 interactions

NUP98 RANBP2 NUP214

1.69e-0551203int:RPS6KL1
InteractionNUP43 interactions

NUP98 RANBP2 NUP62 NUP214 NUP54 TCF20

2.32e-05625206int:NUP43
InteractionNXF1 interactions

NUP98 TARDBP RANBP2 NUP62 NUP214 SARAF NUP54 KIF3B

2.35e-051345208int:NXF1
InteractionNUP133 interactions

NUP98 RANBP2 NUP62 NUP214

2.39e-05175204int:NUP133
InteractionNUP160 interactions

NUP98 RANBP2 NUP62 NUP214

2.84e-05183204int:NUP160
InteractionSMC5 interactions

NUP98 AGFG1 TARDBP RANBP2 NUP62 NUP214 TCF20

3.18e-051000207int:SMC5
InteractionAPC interactions

NUP98 AGFG1 RANBP2 NUP214 NUP54

3.19e-05389205int:APC
InteractionNXF2 interactions

TRO NUP62 NUP214

3.51e-0565203int:NXF2
InteractionNUPR1 interactions

NUP98 RANBP2 NUP62 NUP214 NUP54 FLG2

3.82e-05683206int:NUPR1
InteractionCTIF interactions

NUP62 NUP214 NUP54

5.83e-0577203int:CTIF
InteractionXPOT interactions

NUP98 RANBP2 NUP62 NUP214

5.84e-05220204int:XPOT
InteractionSYNE3 interactions

NUP98 RANBP2 NUP62 NUP214 TCF20

5.99e-05444205int:SYNE3
InteractionRICTOR interactions

RGPD4 TARDBP NUP214 RGPD3 KIF3B FLG2

6.89e-05759206int:RICTOR
InteractionITSN1 interactions

AGFG1 AGFG2 NUP62 NUP214

1.10e-04259204int:ITSN1
InteractionCLEC11A interactions

NUP98 NUP214 TCF20

1.13e-0496203int:CLEC11A
InteractionMAPRE1 interactions

NUP98 RANBP2 NUP62 NUP214 NUP54

1.19e-04514205int:MAPRE1
InteractionNUP93 interactions

NUP98 RANBP2 NUP62 NUP214

1.27e-04269204int:NUP93
InteractionSERPINB2 interactions

NUP214 SARAF NUP54

1.39e-04103203int:SERPINB2
InteractionTPR interactions

NUP98 RANBP2 NUP62 NUP214

1.50e-04281204int:TPR
InteractionKPNB1 interactions

NUP98 RANBP2 NUP62 NUP214 NUP54

1.56e-04544205int:KPNB1
InteractionOBSL1 interactions

NUP98 RANBP2 NUP62 NUP214 NUP54 TCF20

1.78e-04902206int:OBSL1
InteractionAGFG2 interactions

AGFG1 AGFG2

2.14e-0422202int:AGFG2
InteractionRAPGEF3 interactions

NUP98 RANBP2

2.14e-0422202int:RAPGEF3
InteractionNAA40 interactions

NUP98 AGFG1 TARDBP RANBP2 NUP62 NUP214

2.77e-04978206int:NAA40
InteractionMAGEA3 interactions

RANBP2 SCCPDH FLG2

3.02e-04134203int:MAGEA3
InteractionNUP50 interactions

NUP98 RANBP2 NUP214 TCF20

3.15e-04341204int:NUP50
InteractionPHF21A interactions

RANBP2 NUP62 ZMIZ2 NUP214

3.22e-04343204int:PHF21A
InteractionCTNNB1 interactions

NUP98 TARDBP RANBP2 ZMIZ2 NUP214 KIF3B

3.28e-041009206int:CTNNB1
InteractionUSP53 interactions

NUP98 NUP214 SCCPDH

3.29e-04138203int:USP53
InteractionNUP188 interactions

NUP98 NUP62 NUP214

4.04e-04148203int:NUP188
InteractionTBX5 interactions

NUP98 RANBP2 NUP62

4.20e-04150203int:TBX5
InteractionTLE3 interactions

AGFG2 ZMIZ2 NUP54 TCF20

4.56e-04376204int:TLE3
InteractionRNF113A interactions

NUP98 TARDBP RANBP2 NUP62 NUP214

4.75e-04692205int:RNF113A
InteractionMCM2 interactions

RGPD4 TARDBP RANBP2 NUP62 SNX33 RGPD3

4.75e-041081206int:MCM2
InteractionHDAC1 interactions

NUP98 RANBP2 ZMIZ2 NUP214 NUP54 TCF20

5.42e-041108206int:HDAC1
InteractionIFI16 interactions

NUP98 NUP62 NUP214 RGPD3 NUP54

5.48e-04714205int:IFI16
InteractionIPO5 interactions

NUP98 RANBP2 NUP62 NUP214

6.55e-04414204int:IPO5
InteractionXPO7 interactions

NUP98 RANBP2 NUP62

6.80e-04177203int:XPO7
InteractionNKX2-1 interactions

NUP98 NUP62 TCF20

7.14e-04180203int:NKX2-1
InteractionPPM1E interactions

TARDBP TRO

7.50e-0441202int:PPM1E
InteractionBTF3 interactions

RGPD4 TARDBP RANBP2 RGPD3 FLG2

9.12e-04799205int:BTF3
InteractionRCC1 interactions

NUP98 RANBP2 RGPD3

9.83e-04201203int:RCC1
InteractionNXT2 interactions

RANBP2 NUP214

1.03e-0348202int:NXT2
InteractionNUP155 interactions

NUP98 NUP62 NUP214 NUP54

1.11e-03477204int:NUP155
InteractionCUL7 interactions

NUP98 TARDBP RANBP2 NUP214 SNX33

1.17e-03845205int:CUL7
InteractionBFSP1 interactions

NUP62 NUP54

1.20e-0352202int:BFSP1
InteractionKPNA4 interactions

RANBP2 ZMIZ2 RGPD3

1.36e-03225203int:KPNA4
InteractionKIF3B interactions

RANBP2 KIF3B

1.60e-0360202int:KIF3B
InteractionDDX19B interactions

NUP62 NUP214 NUP54

1.86e-03251203int:DDX19B
InteractionNUP37 interactions

NUP98 NUP214

1.87e-0365202int:NUP37
InteractionC14orf119 interactions

NUP62 NUP54

1.99e-0367202int:C14orf119
InteractionSOX2 interactions

NUP98 TARDBP RANBP2 ZMIZ2 NUP214 TCF20

2.00e-031422206int:SOX2
InteractionADAM15 interactions

NUP62 SNX33

2.11e-0369202int:ADAM15
InteractionCTDSPL2 interactions

TARDBP RANBP2

2.17e-0370202int:CTDSPL2
InteractionPRC1 interactions

NUP98 TARDBP RANBP2 RGPD3 KIF3B

2.19e-03973205int:PRC1
InteractionNR3C1 interactions

NUP98 NUP62 NUP214 NUP54 TCF20

2.20e-03974205int:NR3C1
InteractionCIT interactions

NUP98 TARDBP RANBP2 RGPD3 NUP54 TCF20

2.21e-031450206int:CIT
InteractionDGCR6 interactions

NUP62 NUP54

2.36e-0373202int:DGCR6
InteractionB9D2 interactions

NUP98 RGPD3

2.36e-0373202int:B9D2
Cytoband2q12.3

RGPD4 RANBP2

2.44e-05172022q12.3
CytobandEnsembl 112 genes in cytogenetic band chr2q12

RGPD4 RGPD3

5.86e-0482202chr2q12
GeneFamilyNucleoporins

NUP98 RANBP2 NUP62 NUP214 NUP54

3.71e-11321551051
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 RANBP2 RGPD3

1.08e-04115153769
GeneFamilyArfGAPs

AGFG1 AGFG2

3.34e-0433152395
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP

RGPD4 RANBP2 RGPD3

2.04e-0633203MM477
CoexpressionTABULA_MURIS_SENIS_TRACHEA_GRANULOCYTE_AGEING

RGPD4 RANBP2 RGPD3

4.60e-0643203MM3857
CoexpressionGSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_DN

NUP62 NUP214 KIF3B TCF20

1.45e-05200204M5851
CoexpressionGINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN

TARDBP NUP62 ZMIZ2 NUP214

1.12e-04338204M17094
DrugPhe-gly

NUP98 AGFG2 NUP214 NUP54

4.53e-0773204CID000098207
Diseasebrain disease (is_implicated_in)

RANBP2 NUP214

2.31e-0512182DOID:936 (is_implicated_in)
Diseasecognitive inhibition measurement

SCCPDH TCF20

4.23e-0450182EFO_0007969
DiseaseAcute Myeloid Leukemia, M1

NUP98 NUP214

2.61e-03125182C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

NUP98 NUP214

2.61e-03125182C1879321
DiseaseLeukemia, Myelocytic, Acute

NUP98 NUP214

4.92e-03173182C0023467
Diseaseobsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa

OLFM4 TCF20

6.51e-03200182EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351
Diseaseage at menopause

NUP62 SCCPDH

1.43e-02302182EFO_0004704
Diseasecognitive function measurement, self reported educational attainment

ZMIZ2 TCF20

1.94e-02355182EFO_0004784, EFO_0008354

Protein segments in the cluster

PeptideGeneStartEntry
GNSSATGSLFGFSFN

RANBP2

2536

P49792
QSTGFGQYGSGSGQS

FLG2

576

Q5D862
QSTGFGQYGSGSGQS

FLG2

651

Q5D862
QSSGFGQYGSGSGQS

FLG2

1111

Q5D862
QSTGFGQYGSGSGQS

FLG2

1201

Q5D862
GFGTTSTFGQNTGFG

NUP98

16

P52948
STFGQNTGFGTTSGG

NUP98

21

P52948
AFGTSAFGSSNNTGG

NUP98

36

P52948
AFGSSNNTGGLFGNS

NUP98

41

P52948
GFGNFGTSTSSGGLF

NUP98

116

P52948
SNFGFGTNTSGNSIF

NUP98

406

P52948
KGFGYQTGQSFSGEF

KY

251

Q8NBH2
FGQTTFGQASVFGQS

NUP214

1721

P35658
GFGSSNTGSVFGQAA

NUP214

1841

P35658
GGSVASQGFGFSSPN

NUP214

1951

P35658
QQTSGFGTQSSGFSG

NUP214

2051

P35658
FGTQSSGFSGFGSGT

NUP214

2056

P35658
FGSGTGGFSFGSNNS

NUP214

2066

P35658
GGFSFGSNNSSVQGF

NUP214

2071

P35658
GFSFSTSGTGGFNFG

NUP62

31

P37198
TQNKGFGFGTGFGTT

NUP54

56

Q7Z3B4
GNSSATGSLFGFSFN

RGPD3

1561

A6NKT7
GNSSATGSLFGFSFN

RGPD4

1561

Q7Z3J3
AFGSGNNSYSGSNSG

TARDBP

366

Q13148
FTLTFFGQGYSQGTG

SCCPDH

336

Q8NBX0
QNTGHGATSGFGSAF

SARAF

236

Q96BY9
GATSGFGSAFTGQQG

SARAF

241

Q96BY9
FGSAFTGQQGYENSG

SARAF

246

Q96BY9
SGGGSGFLSNQGSFE

SNX33

96

Q8WV41
GSGGSVSQLFSNFTG

OLFM4

61

Q6UX06
ANFDAFGQSSGSSNF

AGFG1

241

P52594
FGQSSGSSNFGGFPT

AGFG1

246

P52594
QGGFANFDAFSSGPS

AGFG2

256

O95081
SAGFGGALNTNASFG

TRO

1056

Q12816
GFSFGNGLSTNAGFG

TRO

1196

Q12816
QGFNGTIFAYGQTGT

KIF3B

86

O15066
QMFQNFGGTGGSSGS

TCF20

36

Q9UGU0
FNGQGASFNGGSVSY

ZMIZ2

336

Q8NF64