Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	ATRX RSF1 CHD9 CHD1L TOP2B RAD50	1.64e-06	127	57	6	GO:0008094
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	ATRX RSF1 CHD9 CHD1L	3.67e-06	37	57	4	GO:0140658
GeneOntologyMolecularFunction	ATP-dependent activity	MYH11 ATRX ATP6V1D RSF1 CHD9 CHD1L DDX27 TOP2B RAD50	5.58e-05	614	57	9	GO:0140657
GeneOntologyMolecularFunction	helicase activity	ATRX CHD9 CHD1L DDX27 RAD50	8.75e-05	158	57	5	GO:0004386
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	ATRX RSF1 CHD9 CHD1L TOP2B RAD50	9.98e-05	262	57	6	GO:0140097
GeneOntologyMolecularFunction	chromatin-protein adaptor activity	BAZ2A MPHOSPH8 CHD1L	2.18e-04	41	57	3	GO:0140463
GeneOntologyMolecularFunction	modification-dependent protein binding	ATRX KDM5A BAZ2A MPHOSPH8 CHD1L	3.01e-04	206	57	5	GO:0140030
GeneOntologyMolecularFunction	histone binding	ATRX KDM5A BAZ2A RSF1 MPHOSPH8	9.45e-04	265	57	5	GO:0042393
GeneOntologyMolecularFunction	molecular adaptor activity	TCERG1L KDM5A BAZ2A ANKRD1 MPHOSPH8 ICE1 CHD1L TRDN MTDH SEPTIN6 RAD50	1.38e-03	1356	57	11	GO:0060090
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	TCERG1L KDM5A BAZ2A ANKRD1 MPHOSPH8 ICE1 CHD1L TRDN MTDH RAD50	1.50e-03	1160	57	10	GO:0030674
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	RALA ATRX RSF1 CHD9 CHD1L DDX27 SEPTIN6 RAD50	1.52e-03	775	57	8	GO:0017111
GeneOntologyMolecularFunction	ATP hydrolysis activity	ATRX RSF1 CHD9 CHD1L DDX27 RAD50	1.57e-03	441	57	6	GO:0016887
GeneOntologyMolecularFunction	methylated histone binding	ATRX KDM5A MPHOSPH8	1.91e-03	86	57	3	GO:0035064
GeneOntologyMolecularFunction	SMAD binding	PARP1 ANKRD1 SMAD5	1.91e-03	86	57	3	GO:0046332
GeneOntologyMolecularFunction	methylation-dependent protein binding	ATRX KDM5A MPHOSPH8	2.04e-03	88	57	3	GO:0140034
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	ATRX RSF1 CHD9 CHD1L DDX27 TOP2B RAD50	2.31e-03	645	57	7	GO:0140640
GeneOntologyMolecularFunction	R-SMAD binding	PARP1 ANKRD1	2.49e-03	26	57	2	GO:0070412
GeneOntologyMolecularFunction	histone reader activity	MPHOSPH8 CHD1L	2.49e-03	26	57	2	GO:0140566
GeneOntologyMolecularFunction	pyrophosphatase activity	RALA ATRX RSF1 CHD9 CHD1L DDX27 SEPTIN6 RAD50	2.50e-03	839	57	8	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	RALA ATRX RSF1 CHD9 CHD1L DDX27 SEPTIN6 RAD50	2.52e-03	840	57	8	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	RALA ATRX RSF1 CHD9 CHD1L DDX27 SEPTIN6 RAD50	2.52e-03	840	57	8	GO:0016818
GeneOntologyMolecularFunction	actin monomer binding	MTSS1 MTSS2	3.09e-03	29	57	2	GO:0003785
GeneOntologyMolecularFunction	chromatin binding	NELFE PARP1 ATRX KDM5A MPHOSPH8 CHD1L TOP2B	4.89e-03	739	57	7	GO:0003682
GeneOntologyBiologicalProcess	replication fork processing	PARP1 ATRX BOD1L1 RAD50	1.20e-05	52	56	4	GO:0031297
GeneOntologyBiologicalProcess	DNA-templated DNA replication maintenance of fidelity	PARP1 ATRX BOD1L1 RAD50	2.12e-05	60	56	4	GO:0045005
GeneOntologyCellularComponent	heterochromatin	ATRX BAZ2A MPHOSPH8 TOP2B	1.55e-04	101	56	4	GO:0000792
GeneOntologyCellularComponent	cleavage furrow	RALA DIAPH3 SEPTIN6	5.87e-04	61	56	3	GO:0032154
GeneOntologyCellularComponent	ISWI-type complex	BAZ2A RSF1	6.28e-04	14	56	2	GO:0031010
HumanPheno	Cerebral artery stenosis	MYH11 NF1	1.80e-05	3	13	2	HP:0012492
HumanPheno	Functional abnormality of the inner ear	MYH11 NF1 ATRX ANKRD1 DUOX2 DIAPH3 RRM1 TRDN LETM1 MTSS2	2.62e-05	1077	13	10	HP:0011389
HumanPheno	Abnormality of the inner ear	MYH11 NF1 ATRX ANKRD1 DUOX2 DIAPH3 RRM1 TRDN LETM1 MTSS2	3.24e-05	1102	13	10	HP:0000359
Domain	MIM/ABBA	MTSS1 MTSS2	7.60e-06	2	52	2	IPR030127
Domain	WHIM1	BAZ2A RSF1	7.56e-05	5	52	2	PF15612
Domain	IMD	MTSS1 MTSS2	7.56e-05	5	52	2	PS51338
Domain	WHIM1_dom	BAZ2A RSF1	7.56e-05	5	52	2	IPR028942
Domain	SNF2_N	ATRX CHD9 CHD1L	9.54e-05	32	52	3	IPR000330
Domain	SNF2_N	ATRX CHD9 CHD1L	9.54e-05	32	52	3	PF00176
Domain	DDT	BAZ2A RSF1	1.13e-04	6	52	2	PS50827
Domain	IMD	MTSS1 MTSS2	1.13e-04	6	52	2	PF08397
Domain	ZF_PHD_2	ATRX KDM5A BAZ2A RSF1	1.41e-04	95	52	4	PS50016
Domain	ZF_PHD_1	ATRX KDM5A BAZ2A RSF1	1.47e-04	96	52	4	PS01359
Domain	Helicase_C	ATRX CHD9 CHD1L DDX27	2.23e-04	107	52	4	PF00271
Domain	HELICc	ATRX CHD9 CHD1L DDX27	2.23e-04	107	52	4	SM00490
Domain	Helicase_C	ATRX CHD9 CHD1L DDX27	2.31e-04	108	52	4	IPR001650
Domain	HELICASE_CTER	ATRX CHD9 CHD1L DDX27	2.40e-04	109	52	4	PS51194
Domain	HELICASE_ATP_BIND_1	ATRX CHD9 CHD1L DDX27	2.40e-04	109	52	4	PS51192
Domain	DEXDc	ATRX CHD9 CHD1L DDX27	2.40e-04	109	52	4	SM00487
Domain	Helicase_ATP-bd	ATRX CHD9 CHD1L DDX27	2.48e-04	110	52	4	IPR014001
Domain	I-BAR_dom	MTSS1 MTSS2	5.82e-04	13	52	2	IPR013606
Domain	Znf_FYVE_PHD	ATRX KDM5A BAZ2A RSF1	7.44e-04	147	52	4	IPR011011
Domain	PHD	KDM5A BAZ2A RSF1	1.19e-03	75	52	3	PF00628
Domain	Znf_PHD-finger	KDM5A BAZ2A RSF1	1.39e-03	79	52	3	IPR019787
Domain	-	ATRX MYCBP2 KDM5A BAZ2A RSF1 SH3RF3	1.49e-03	449	52	6	3.30.40.10
Domain	Znf_RING/FYVE/PHD	ATRX MYCBP2 KDM5A BAZ2A RSF1 SH3RF3	1.67e-03	459	52	6	IPR013083
Domain	PHD	KDM5A BAZ2A RSF1	1.95e-03	89	52	3	SM00249
Domain	Chromo_domain	CHD9 MPHOSPH8	2.02e-03	24	52	2	IPR023780
Domain	WH2	MTSS1 MTSS2	2.02e-03	24	52	2	PS51082
Domain	Znf_PHD	KDM5A BAZ2A RSF1	2.08e-03	91	52	3	IPR001965
Domain	P-loop_NTPase	RALA MYH11 ATRX CHD9 CHD1L DDX27 SEPTIN6 RAD50	2.23e-03	848	52	8	IPR027417
Domain	Chromo	CHD9 MPHOSPH8	2.37e-03	26	52	2	PF00385
Domain	AT_hook	BAZ2A BOD1L1	2.55e-03	27	52	2	SM00384
Domain	AT_hook_DNA-bd_motif	BAZ2A BOD1L1	2.55e-03	27	52	2	IPR017956
Domain	CHROMO_1	CHD9 MPHOSPH8	2.74e-03	28	52	2	PS00598
Domain	CHROMO_2	CHD9 MPHOSPH8	2.74e-03	28	52	2	PS50013
Domain	Chromodomain-like	CHD9 MPHOSPH8	3.57e-03	32	52	2	IPR016197
Domain	Chromo/shadow_dom	CHD9 MPHOSPH8	3.80e-03	33	52	2	IPR000953
Domain	CHROMO	CHD9 MPHOSPH8	3.80e-03	33	52	2	SM00298
Domain	-	RALA ATRX CHD9 CHD1L DDX27 SEPTIN6 RAD50	4.41e-03	746	52	7	3.40.50.300
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FAM133B RALA PARP1 MYH11 UTP18 TCERG1L ATRX KDM5A FAM186A RSF1 SYCP1 DUOX2 BOD1L1 MPHOSPH8 LSM14A DIAPH3 CEP57 TRDN MTDH LETM1 TOP2B ESF1 DOP1A UTP14C	1.12e-18	1442	57	24	35575683
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	NELFE FAM193B PARP1 ATRX BAZ2A RSF1 BOD1L1 LSM14A ICE1 MTDH DEPDC1B TOP2B ESF1 RAD50	2.43e-10	934	57	14	33916271
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	RALA PARP1 UTP18 NF1 ATRX RBM19 DUOX2 BOD1L1 MPHOSPH8 MTDH DDX27 LETM1 TOP2B ESF1 RAD50	6.24e-09	1425	57	15	30948266
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	NELFE PARP1 ATRX BAZ2A BOD1L1 MTDH TOP2B ESF1	2.04e-08	283	57	8	30585729
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	NELFE PARP1 ATRX BAZ2A RBM19 RSF1 BOD1L1 MPHOSPH8 ICE1 MTDH TOP2B ESF1	3.85e-08	954	57	12	36373674
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NELFE UTP18 NF1 ATRX MYCBP2 KDM5A BAZ2A CPSF2 TOP2B ESF1 RAD50	4.49e-08	774	57	11	15302935
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	PARP1 ATRX KDM5A BAZ2A RSF1 CHD9 BOD1L1 MPHOSPH8 CHD1L TOP2B	5.11e-08	608	57	10	36089195
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	NELFE PARP1 ATRX RSF1 CHD9 BOD1L1 MPHOSPH8 CHD1L CPSF2 TOP2B ESF1 RAD50	7.47e-08	1014	57	12	32416067
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	PARP1 UTP18 ATRX MYCBP2 BAZ2A CCDC18 DIAPH3 RRM1 MTDH DDX27 DEPDC1B LETM1 TOP2B ESF1	8.79e-08	1487	57	14	33957083
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	PARP1 UTP18 ATRX BAZ2A RBM19 RSF1 DDX27 RAD50	1.02e-07	349	57	8	25665578
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NELFE NF1 ARHGEF28 MYCBP2 KDM5A CCDC18 BOD1L1 SH3RF3 DEPDC1B DOP1A MTSS2	1.31e-07	861	57	11	36931259
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PARP1 UTP18 NF1 MYCBP2 BAZ2A RBM19 RSF1 CHD1L RRM1 DDX27 TOP2B ESF1 RAD50	2.19e-07	1353	57	13	29467282
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	NELFE RALA PARP1 MYH11 KDM5A RBM19 LSM14A CHD1L CPSF2 PIPSL MTDH DDX27 SEPTIN6	2.55e-07	1371	57	13	36244648
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	NELFE PARP1 UTP18 RBM19 ANKRD1 BOD1L1 MPHOSPH8 DDX27 TOP2B ESF1 RAD50	5.19e-07	989	57	11	36424410
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PARP1 UTP18 TBRG1 ATRX KDM5A BAZ2A MPHOSPH8 CHD1L CPSF2 MTDH TOP2B RAD50	1.00e-06	1294	57	12	30804502
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	PARP1 MYH11 SLC13A4 ATP6V1D BOD1L1 PIPSL RRM1 SEPTIN6 DOP1A RAD50	1.07e-06	847	57	10	35235311
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	UTP18 BAZ2A RBM19 MPHOSPH8 DDX27 TOP2B ESF1	1.19e-06	332	57	7	25693804
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	PARP1 FAM186A SYCP1 TOP2B UTP14C RAD50	2.37e-06	234	57	6	36243803
Pubmed	Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation.	NELFE PARP1	2.64e-06	2	57	2	27256882
Pubmed	Activation of the SNF2 family ATPase ALC1 by poly(ADP-ribose) in a stable ALC1·PARP1·nucleosome intermediate.	PARP1 CHD1L	2.64e-06	2	57	2	23132853
Pubmed	The chromatin remodeler ALC1 underlies resistance to PARP inhibitor treatment.	PARP1 CHD1L	2.64e-06	2	57	2	33355125
Pubmed	CHD1L Regulated PARP1-Driven Pluripotency and Chromatin Remodeling During the Early-Stage Cell Reprogramming.	PARP1 CHD1L	2.64e-06	2	57	2	26201266
Pubmed	Multiple roles for PARP1 in ALC1-dependent nucleosome remodeling.	PARP1 CHD1L	2.64e-06	2	57	2	34465625
Pubmed	CHD1L: a new candidate gene for congenital anomalies of the kidneys and urinary tract (CAKUT).	PARP1 CHD1L	2.64e-06	2	57	2	22146311
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	FAM133B PARP1 RSF1 BOD1L1 CPSF2 TOP2B	3.55e-06	251	57	6	31076518
Pubmed	Nucleolar proteome dynamics.	PARP1 ATRX RBM19 DDX27 TOP2B ESF1 RAD50	5.51e-06	419	57	7	15635413
Pubmed	Interactome Analysis of the Nucleocapsid Protein of SARS-CoV-2 Virus.	UTP18 MTDH DDX27 LETM1 ESF1	6.48e-06	159	57	5	34578187
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	PARP1 NF1 ATRX MYCBP2 DDX27 TOP2B ESF1	7.58e-06	440	57	7	34244565
Pubmed	Ral overactivation in malignant peripheral nerve sheath tumors.	RALA NF1	7.91e-06	3	57	2	19414599
Pubmed	PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1.	PARP1 CHD1L	7.91e-06	3	57	2	23045548
Pubmed	Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling.	PARP1 CHD1L	7.91e-06	3	57	2	34874266
Pubmed	TopoisomeraseIIβ in HIV-1 transactivation.	PARP1 TOP2B	7.91e-06	3	57	2	26876283
Pubmed	The functional interactome landscape of the human histone deacetylase family.	UTP18 MYCBP2 KDM5A ANKRD12 CEP57 DDX27	7.95e-06	289	57	6	23752268
Pubmed	The DNA sequence and analysis of human chromosome 13.	MYCBP2 MPHOSPH8 DIAPH3 ZMYM5 UTP14C	8.97e-06	170	57	5	15057823
Pubmed	MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.	SYCP1 UTP14C RAD50	1.06e-05	26	57	3	35920200
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	NELFE PARP1 UTP18 RSF1 RRM1 MTDH DDX27 LETM1	1.09e-05	653	57	8	33742100
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	UTP18 NF1 MYCBP2 BAZ2A RSF1 DDX27 ESF1 RAD50	1.09e-05	653	57	8	22586326
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	ATRX RSF1 TOP2B UTP14C	1.25e-05	86	57	4	37253089
Pubmed	Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.	PARP1 ATRX RSF1 TOP2B RAD50	1.46e-05	188	57	5	29721183
Pubmed	Direct measurement of protein-protein interactions by FLIM-FRET at UV laser-induced DNA damage sites in living cells.	PARP1 CHD1L	1.58e-05	4	57	2	33053171
Pubmed	ABBA regulates plasma-membrane and actin dynamics to promote radial glia extension.	MTSS1 MTSS2	1.58e-05	4	57	2	18413296
Pubmed	A novel actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis protein.	MTSS1 MTSS2	1.58e-05	4	57	2	14752106
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	PARP1 ATRX BOD1L1 CPSF2 RRM1 RAD50	1.74e-05	332	57	6	32786267
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	NELFE TBRG1 MYCBP2 KDM5A RBM19 DIAPH3 MTDH TOP2B	2.28e-05	724	57	8	36232890
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	PARP1 CHD9 BOD1L1 DOP1A RAD50	2.37e-05	208	57	5	33230847
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RALA ATRX MYCBP2 CHD9 BOD1L1 LSM14A CHD1L ANKRD12 SH3RF3 SEPTIN6 DOP1A	2.56e-05	1489	57	11	28611215
Pubmed	Poly(ADP-ribose) polymerases PARP1 and PARP2 modulate topoisomerase II beta (TOP2B) function during chromatin condensation in mouse spermiogenesis.	PARP1 TOP2B	2.63e-05	5	57	2	21228215
Pubmed	ATRX dysfunction induces replication defects in primary mouse cells.	ATRX RAD50	2.63e-05	5	57	2	24651726
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	FAM133B ATRX KDM5A BAZ2A RBM19 MPHOSPH8 LSM14A ICE1 CPSF2 DDX27 ESF1	2.69e-05	1497	57	11	31527615
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NELFE MYCBP2 BAZ2A BOD1L1 DIAPH3 ESF1 RAD50	3.14e-05	549	57	7	38280479
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	FAM133B UTP18 MYCBP2 LSM14A MTDH DDX27 TOP2B ESF1	3.19e-05	759	57	8	35915203
Pubmed	Poly(ADP-ribose) Polymerase 1 Interacts with Nuclear Respiratory Factor 1 (NRF-1) and Plays a Role in NRF-1 Transcriptional Regulation.	PARP1 TOP2B	3.94e-05	6	57	2	19181665
Pubmed	Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary.	PARP1 TOP2B	3.94e-05	6	57	2	19450526
Pubmed	Tripartite Motif-containing 33 (TRIM33) protein functions in the poly(ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein.	PARP1 CHD1L	3.94e-05	6	57	2	23926104
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RALA PARP1 NF1 MYCBP2 CPSF2 MTDH DDX27 TOP2B RAD50	4.06e-05	1024	57	9	24711643
Pubmed	Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates.	NELFE PARP1 TOP2B	4.26e-05	41	57	3	15561718
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	PARP1 NF1 ATRX CHD1L DIAPH3 CPSF2 RAD50	4.54e-05	582	57	7	20467437
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	FAM133B PARP1 UTP18 RBM19 LSM14A MTDH DDX27 ESF1	4.91e-05	807	57	8	22681889
Pubmed	An Interaction Network of the Human SEPT9 Established by Quantitative Mass Spectrometry.	LSM14A ICE1 MTDH	4.92e-05	43	57	3	30975701
Pubmed	Functional proteomics mapping of a human signaling pathway.	RALA ATRX MYCBP2 RBM19 DIAPH3 ZMYM5 SMAD5	5.00e-05	591	57	7	15231748
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	FAM133B PARP1 UTP18 KDM5A BAZ2A CHD1L CPSF2 MTDH DDX27 TOP2B	5.03e-05	1318	57	10	30463901
Pubmed	A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription.	PARP1 TOP2B	5.51e-05	7	57	2	16794079
Pubmed	Topoisomerase II regulates the maintenance of DNA methylation.	PARP1 TOP2B	5.51e-05	7	57	2	25451918
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	PARP1 UTP18 RBM19 CPSF2 MTDH DDX27 TOP2B	5.79e-05	605	57	7	28977666
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	MYCBP2 KDM5A ICE1 DIAPH3 ZMYM5 RAD50	6.29e-05	418	57	6	34709266
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ATRX BOD1L1 ANKRD12 CPSF2 MTDH LETM1 SEPTIN6 ESF1 UTP14C	6.30e-05	1084	57	9	11544199
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	NELFE PARP1 UTP18 CPSF2 MTDH DDX27 TOP2B	6.42e-05	615	57	7	31048545
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	NELFE PARP1 MYCBP2 CHD9 LSM14A RRM1 TOP2B SEPTIN6 RAD50	7.19e-05	1103	57	9	34189442
Pubmed	HIV-1 Vpr modulates macrophage metabolic pathways: a SILAC-based quantitative analysis.	RALA MYH11 MTDH LETM1	7.31e-05	135	57	4	23874603
Pubmed	Nuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy.	TOP2B RAD50	7.34e-05	8	57	2	28345663
Pubmed	The human Rap1 protein complex and modulation of telomere length.	PARP1 RAD50	7.34e-05	8	57	2	15100233
Pubmed	Smicl is a novel Smad interacting protein and cleavage and polyadenylation specificity factor associated protein.	CPSF2 SMAD5	7.34e-05	8	57	2	16115198
Pubmed	Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice.	PARP1 ATRX	7.34e-05	8	57	2	9607915
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	PARP1 CPSF2 MTDH ESF1 RAD50	8.77e-05	274	57	5	34244482
Pubmed	Vigilin interacts with CCCTC-binding factor (CTCF) and is involved in CTCF-dependent regulation of the imprinted genes Igf2 and H19.	RALA CHD1L	9.43e-05	9	57	2	24725430
Pubmed	The male germline-specific protein MAPS is indispensable for pachynema progression and fertility.	PARP1 SYCP1	9.43e-05	9	57	2	33602822
Pubmed	Intercellular bridges coordinate the transition from pluripotency to meiosis in mouse fetal oocytes.	PARP1 SYCP1	9.43e-05	9	57	2	33827806
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	NELFE ATRX TOP2B ESF1	1.04e-04	148	57	4	32538781
Pubmed	XY oocytes of sex-reversed females with a Sry mutation deviate from the normal developmental process beyond the mitotic stage†.	PARP1 SYCP1	1.18e-04	10	57	2	30289439
Pubmed	A role of DNA-PK for the metabolic gene regulation in response to insulin.	PARP1 TOP2B	1.18e-04	10	57	2	19303849
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	PARP1 UTP18 RBM19 MTDH DDX27 ESF1	1.39e-04	483	57	6	36912080
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	PARP1 UTP18 MYCBP2 BAZ2A DIAPH3 MTDH DDX27 DEPDC1B LETM1 ESF1	1.43e-04	1496	57	10	32877691
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	NELFE FAM133B UTP18 MPHOSPH8 LSM14A CPSF2 TOP2B	1.45e-04	701	57	7	30196744
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	UTP18 RSF1 LSM14A MTDH	1.51e-04	163	57	4	22113938
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	RALA PARP1 BOD1L1 DIAPH3 RRM1 DEPDC1B LETM1	1.54e-04	708	57	7	39231216
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FAM193B MYH11 ARHGEF28 SEPTIN6 DOP1A UTP14C	1.55e-04	493	57	6	15368895
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	NF1 BOD1L1 CPSF2 DEPDC1B SMAD5	1.63e-04	313	57	5	38270169
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	PARP1 NF1 MYCBP2 KDM5A CPSF2 LETM1 MTSS2 RAD50	1.67e-04	963	57	8	28671696
Pubmed	ATRX directs binding of PRC2 to Xist RNA and Polycomb targets.	PARP1 ATRX	1.72e-04	12	57	2	25417162
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	RALA PARP1 UTP18 RBM19 LSM14A MTDH DDX27 ESF1 RAD50	1.93e-04	1257	57	9	36526897
Pubmed	SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline.	PARP1 SYCP1	2.03e-04	13	57	2	34912016
Pubmed	Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk.	ATRX RAD50	2.03e-04	13	57	2	19064565
Pubmed	BMP signaling controls formation of a primordial germ cell niche within the early genital ridges.	PARP1 SMAD5	2.03e-04	13	57	2	20417197
Pubmed	Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.	MTSS1 MTSS2	2.03e-04	13	57	2	21406566
Pubmed	Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.	ATRX KDM5A ICE1 UTP14C	2.08e-04	177	57	4	26206133
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	PARP1 RRM1 LETM1 RAD50	2.17e-04	179	57	4	36261009
Pubmed	Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.	PARP1 ATRX BAZ2A	2.30e-04	72	57	3	31248990
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	NELFE ATRX RSF1 CHD9 DDX27 TOP2B	2.36e-04	533	57	6	30554943
Pubmed	SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation.	MYH11 SMAD5	2.37e-04	14	57	2	20110314
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	PARP1 RBM19 RSF1 TOP2B RAD50	2.39e-04	340	57	5	29478914
Interaction	NAA40 interactions	NELFE FAM193B PARP1 ATRX BAZ2A RSF1 BOD1L1 LSM14A ICE1 MTDH DEPDC1B TOP2B ESF1 RAD50	3.99e-07	978	57	14	int:NAA40
Interaction	H2BC12 interactions	MYH11 ATRX DUOX2 CHD1L RRM1 MTDH DDX27 TOP2B	3.26e-06	322	57	8	int:H2BC12
Interaction	SMC5 interactions	NELFE PARP1 ATRX BAZ2A RBM19 RSF1 BOD1L1 MPHOSPH8 ICE1 MTDH TOP2B ESF1 RAD50	3.27e-06	1000	57	13	int:SMC5
Interaction	H3-3A interactions	PARP1 ATRX KDM5A BAZ2A RSF1 CHD9 BOD1L1 MPHOSPH8 CHD1L TOP2B RAD50	6.72e-06	749	57	11	int:H3-3A
Interaction	POLR1G interactions	UTP18 RBM19 RSF1 CHD9 ICE1 DDX27 TOP2B ESF1 RAD50	8.66e-06	489	57	9	int:POLR1G
Interaction	H3C3 interactions	PARP1 ATRX KDM5A BAZ2A RSF1 BOD1L1 MPHOSPH8 CHD1L TOP2B	9.55e-06	495	57	9	int:H3C3
Interaction	CBX3 interactions	NELFE PARP1 ATRX BAZ2A RSF1 CHD9 CHD1L RRM1 TOP2B ESF1	1.18e-05	646	57	10	int:CBX3
Interaction	NPM1 interactions	NELFE PARP1 UTP18 NF1 RBM19 SYCP1 CPSF2 TRDN MTDH DDX27 TOP2B ESF1 RAD50	2.35e-05	1201	57	13	int:NPM1
Interaction	ENO1 interactions	NELFE FAM193B MYH11 FAM186A ATP6V1D SYCP1 MPHOSPH8 DIAPH3 RRM1 MTDH	2.39e-05	701	57	10	int:ENO1
Interaction	NOP56 interactions	PARP1 UTP18 ATRX RBM19 MTDH DDX27 TOP2B ESF1 RAD50	2.92e-05	570	57	9	int:NOP56
Interaction	SUPT16H interactions	NELFE PARP1 ATRX RSF1 CHD1L DIAPH3 MTDH TOP2B	3.24e-05	442	57	8	int:SUPT16H
Interaction	CTCF interactions	RALA PARP1 ATRX RBM19 CHD1L MTDH DDX27 TOP2B	4.36e-05	461	57	8	int:CTCF
Interaction	YWHAH interactions	NELFE MYH11 NF1 ARHGEF28 MYCBP2 KDM5A CCDC18 BOD1L1 SH3RF3 DEPDC1B DOP1A MTSS2	4.83e-05	1102	57	12	int:YWHAH
Interaction	XRCC6 interactions	NELFE PARP1 ATRX BAZ2A BOD1L1 ICE1 CHD1L MTDH TOP2B ESF1 RAD50	4.91e-05	928	57	11	int:XRCC6
Interaction	POLR1E interactions	PARP1 UTP18 RBM19 ICE1 TOP2B ESF1 RAD50	5.63e-05	350	57	7	int:POLR1E
Interaction	NUP43 interactions	KDM5A BAZ2A RBM19 RSF1 CHD9 BOD1L1 ICE1 DDX27 TOP2B	5.96e-05	625	57	9	int:NUP43
Interaction	PYHIN1 interactions	PARP1 ATRX BAZ2A RSF1 CPSF2 TOP2B RAD50	6.49e-05	358	57	7	int:PYHIN1
Interaction	ATG16L1 interactions	NELFE FAM133B PARP1 UTP18 ARHGEF28 MYCBP2 MPHOSPH8 LSM14A DIAPH3 CPSF2 DEPDC1B TOP2B	7.99e-05	1161	57	12	int:ATG16L1
Interaction	H2BC4 interactions	PARP1 MYH11 RRM1 MTDH DDX27 TOP2B	8.91e-05	259	57	6	int:H2BC4
Interaction	CENPA interactions	PARP1 ATRX BAZ2A RSF1 DIAPH3 TOP2B ESF1	8.97e-05	377	57	7	int:CENPA
Interaction	ZBTB21 interactions	PARP1 NF1 ATRX SH3RF3 DEPDC1B	9.16e-05	161	57	5	int:ZBTB21
Interaction	H1-2 interactions	NELFE PARP1 ATRX RBM19 RSF1 BOD1L1 RRM1 DDX27 RAD50	9.70e-05	666	57	9	int:H1-2
Interaction	H2BC21 interactions	NELFE PARP1 ATRX RSF1 DUOX2 MPHOSPH8 CHD1L TOP2B RAD50	1.35e-04	696	57	9	int:H2BC21
Interaction	KCNA3 interactions	RALA PARP1 CHD9 BOD1L1 DIAPH3 RRM1 DEPDC1B LETM1 DOP1A RAD50	1.47e-04	871	57	10	int:KCNA3
Interaction	LINC02910 interactions	FAM133B UTP18 MTDH ESF1	1.51e-04	95	57	4	int:LINC02910
Interaction	YWHAG interactions	NELFE NF1 ARHGEF28 MYCBP2 CCDC18 BOD1L1 RRM1 SH3RF3 DDX27 DEPDC1B DOP1A MTSS2	1.58e-04	1248	57	12	int:YWHAG
Interaction	CIT interactions	MYH11 UTP18 RBM19 RSF1 DUOX2 BOD1L1 MPHOSPH8 CPSF2 RRM1 MTDH TOP2B ESF1 UTP14C	1.62e-04	1450	57	13	int:CIT
Interaction	SMARCA5 interactions	NELFE PARP1 BAZ2A RSF1 CPSF2 PIPSL DEPDC1B	1.62e-04	415	57	7	int:SMARCA5
Interaction	CAMK2B interactions	C20orf96 PARP1 NF1 MYCBP2 ZMYM5	1.63e-04	182	57	5	int:CAMK2B
Interaction	IFI16 interactions	PARP1 UTP18 BAZ2A RBM19 MPHOSPH8 MTDH DDX27 TOP2B ESF1	1.64e-04	714	57	9	int:IFI16
Interaction	HMGN4 interactions	PARP1 RBM19 RSF1 DDX27	1.84e-04	100	57	4	int:HMGN4
Interaction	SENP3 interactions	PARP1 MYCBP2 RRM1 DDX27 TOP2B ESF1	2.02e-04	301	57	6	int:SENP3
Interaction	H2BC8 interactions	PARP1 ATRX BAZ2A RSF1 MPHOSPH8 CHD1L TOP2B ESF1	2.04e-04	576	57	8	int:H2BC8
Interaction	RALBP1 interactions	RALA MYH11 TBRG1 CPSF2 CEP57	2.41e-04	198	57	5	int:RALBP1
Interaction	SUMO2 interactions	PARP1 ATRX BOD1L1 CPSF2 RRM1 TOP2B ZMYM5 RAD50	2.43e-04	591	57	8	int:SUMO2
Interaction	NDC80 interactions	ATP6V1D CCDC18 ICE1 DIAPH3 MTDH RAD50	2.45e-04	312	57	6	int:NDC80
Interaction	H2AX interactions	PARP1 ATRX BAZ2A RBM19 RSF1 DUOX2 CHD1L RAD50	2.49e-04	593	57	8	int:H2AX
Interaction	ZNF330 interactions	PARP1 RBM19 RSF1 MPHOSPH8 DDX27 TOP2B ESF1	2.52e-04	446	57	7	int:ZNF330
Interaction	PARP1 interactions	PARP1 UTP18 MYCBP2 RBM19 RSF1 CHD1L CPSF2 RRM1 DDX27 TOP2B ESF1 RAD50	2.60e-04	1316	57	12	int:PARP1
Interaction	CHD4 interactions	NELFE PARP1 UTP18 BAZ2A RBM19 RSF1 CPSF2 MTDH DDX27 TOP2B	2.68e-04	938	57	10	int:CHD4
Interaction	H3C15 interactions	NELFE PARP1 KDM5A RSF1 ESF1	2.96e-04	207	57	5	int:H3C15
Interaction	RTKN interactions	PARP1 NF1 SH3RF3 DEPDC1B	3.15e-04	115	57	4	int:RTKN
Interaction	SIRT6 interactions	PARP1 NF1 ATRX MYCBP2 DDX27 TOP2B ESF1 RAD50	3.65e-04	628	57	8	int:SIRT6
Interaction	NUCKS1 interactions	NELFE PARP1 ATRX RSF1 TOP2B	3.91e-04	220	57	5	int:NUCKS1
Interaction	HECTD1 interactions	FAM133B PARP1 UTP18 MYCBP2 LSM14A CPSF2 MTDH DDX27 TOP2B ESF1	3.92e-04	984	57	10	int:HECTD1
Interaction	FBL interactions	UTP18 BAZ2A RBM19 LSM14A MTDH DDX27 TOP2B ESF1	4.10e-04	639	57	8	int:FBL
Interaction	HMGB1 interactions	NELFE PARP1 ATRX RSF1 TOP2B UTP14C RAD50	4.24e-04	486	57	7	int:HMGB1
Interaction	ESAM interactions	MPHOSPH8 MTDH	4.25e-04	11	57	2	int:ESAM
Interaction	DCLK1 interactions	NF1 MYCBP2 SH3RF3 DEPDC1B	4.59e-04	127	57	4	int:DCLK1
Interaction	EP300 interactions	NELFE PARP1 UTP18 RSF1 RRM1 MTDH DDX27 LETM1 TOP2B SEPTIN6 SMAD5 RAD50	4.60e-04	1401	57	12	int:EP300
Interaction	RHOA interactions	RALA PARP1 UTP18 NF1 ARHGEF28 DIAPH3 MTDH DDX27 DEPDC1B LETM1 TOP2B	4.64e-04	1199	57	11	int:RHOA
Interaction	DAXX interactions	PARP1 MYH11 ATRX CHD9 MPHOSPH8 TOP2B	4.73e-04	353	57	6	int:DAXX
Interaction	RALGPS2 interactions	RALA NF1 SH3RF3	4.80e-04	54	57	3	int:RALGPS2
Interaction	MAST3 interactions	PARP1 NF1 SH3RF3 DEPDC1B	4.87e-04	129	57	4	int:MAST3
Interaction	H2AC17 interactions	PARP1 UTP18 RBM19 CHD1L DDX27	4.98e-04	232	57	5	int:H2AC17
Interaction	SVIL interactions	PARP1 MYH11 ATRX MYCBP2 SYCP1	5.08e-04	233	57	5	int:SVIL
Interaction	CD274 interactions	PARP1 NF1 MTSS1 LSM14A RRM1 MTDH	5.98e-04	369	57	6	int:CD274
Interaction	SSRP1 interactions	NELFE PARP1 ATRX RSF1 MPHOSPH8 CHD1L MTDH TOP2B	6.49e-04	685	57	8	int:SSRP1
Interaction	AATF interactions	PARP1 UTP18 MYCBP2 RBM19 DDX27 ESF1	6.59e-04	376	57	6	int:AATF
Interaction	ANKRD13D interactions	RALA ATP6V1D MTDH	6.87e-04	61	57	3	int:ANKRD13D
Cytoband	5q31	PKD2L2 SMAD5 RAD50	4.06e-04	115	57	3	5q31
GeneFamily	I-BAR domain containing	MTSS1 MTSS2	2.31e-05	5	28	2	1287
GeneFamily	PHD finger proteins	KDM5A BAZ2A RSF1	3.57e-04	90	28	3	88
GeneFamily	RNA binding motif containing	NELFE RBM19 ENOX2	4.25e-03	213	28	3	725
GeneFamily	Ankyrin repeat domain containing	ANKRD1 MPHOSPH8 ANKRD12	6.06e-03	242	28	3	403
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	RALA MYCBP2 RSF1 MPHOSPH8 DIAPH3 CEP57 MTDH TOP2B ESF1 ENOX2 RAD50	1.44e-07	656	57	11	M18979
Coexpression	OSMAN_BLADDER_CANCER_UP	FAM133B ATP6V1D RSF1 CHD9 CEP57 MTDH ESF1 SMAD5	2.45e-06	402	57	8	M5275
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	PARP1 TBRG1 ATRX MYCBP2 KDM5A RSF1 BOD1L1 MPHOSPH8 LSM14A ICE1 MTDH TOP2B ZMYM5 SEPTIN6	2.69e-06	1492	57	14	M40023
Coexpression	TBK1.DF_DN	RALA NF1 RSF1 LSM14A LETM1 ESF1 SMAD5	2.84e-06	286	57	7	M2864
Coexpression	RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	ATRX ANKRD1 RSF1 BOD1L1 DIAPH3 CPSF2 CEP57 DDX27 ESF1 RAD50	3.13e-06	721	57	10	M10237
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	ATRX KDM5A CHD9 LSM14A ICE1 DOP1A SMAD5	3.89e-06	300	57	7	M8702
Coexpression	GSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_DN	UTP18 TBRG1 MTDH DDX27 ESF1 SMAD5	4.67e-06	199	57	6	M6648
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_UP	FAM133B RALA ATRX ATP6V1D LSM14A SEPTIN6 ESF1 UTP14C	1.94e-05	534	57	8	MM1054
Coexpression	GSE11386_NAIVE_VS_MEMORY_BCELL_DN	MYCBP2 MTSS1 RSF1 CHD9 ZMYM5	2.43e-05	158	57	5	M372
Coexpression	GSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_UP	TBRG1 KDM5A CCDC18 CHD9 ICE1	3.17e-05	167	57	5	M365
Coexpression	GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD4_TCELL_DN	NELFE RALA TBRG1 DDX27 SEPTIN6	3.45e-05	170	57	5	M6747
Coexpression	MENON_FETAL_KIDNEY_0_CAP_MESENCHYME_CELLS	ATRX RSF1 TOP2B SEPTIN6	4.47e-05	90	57	4	M39250
Coexpression	CAIRO_HEPATOBLASTOMA_CLASSES_UP	NELFE PARP1 UTP18 RRM1 CEP57 MTDH DDX27 ESF1	5.09e-05	612	57	8	M4772
Coexpression	GSE14308_TH1_VS_INDUCED_TREG_UP	FAM133B ATRX MYCBP2 ANKRD12 RAD50	7.46e-05	200	57	5	M3378
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_UP	FAM133B RALA ATRX ATP6V1D LSM14A SEPTIN6 ESF1	1.35e-04	523	57	7	M12707
Coexpression	KAUFFMANN_DNA_REPAIR_GENES	PARP1 ATRX RRM1 TOP2B RAD50	1.44e-04	230	57	5	M11563
Coexpression	PUJANA_ATM_PCC_NETWORK	PARP1 UTP18 BAZ2A LSM14A ICE1 RRM1 CEP57 MTDH DDX27 TOP2B ENOX2	1.78e-04	1394	57	11	M9585
Coexpression	MURARO_PANCREAS_BETA_CELL	ATRX MYCBP2 ATP6V1D MTSS1 CHD9 MPHOSPH8 ANKRD12 MTSS2 RAD50	1.90e-04	946	57	9	M39169
Coexpression	FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	RALA PARP1 MYH11 MTDH TOP2B SEPTIN6 SMAD5	2.24e-04	568	57	7	M4023
Coexpression	GSE40274_FOXP3_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	BOD1L1 ZMYM5 SMAD5 RAD50	2.68e-04	143	57	4	M9149
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2	RALA ATRX MYCBP2 KDM5A CHD9 LSM14A ICE1 MTDH ESF1 MTSS2 RAD50	1.75e-07	564	55	11	Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	UTP18 KDM5A BAZ2A CCDC18 SYCP1 CHD1L ANKRD12 DIAPH3 FAM228A ESF1 DOP1A RAD50	9.65e-07	820	55	12	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	ATRX RSF1 CHD9 BOD1L1 MPHOSPH8 CPSF2 RRM1 CEP57 MTDH ZMYM5 ESF1 SMAD5 RAD50	1.45e-05	1257	55	13	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	ATRX CCDC18 BOD1L1 LETM1 TOP2B ESF1 RAD50	1.50e-05	311	55	7	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	ATRX KDM5A RSF1 CCDC18 LSM14A CEP57 SH3RF3 ESF1	2.61e-05	469	55	8	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5	ATRX KDM5A CCDC18 CHD9 BOD1L1 LSM14A ESF1 MTSS2 RAD50	3.12e-05	629	55	9	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	UTP18 BAZ2A CCDC18 CHD1L DIAPH3 RAD50	5.35e-05	258	55	6	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k2_1000
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	UTP18 BAZ2A CCDC18 CHD1L ESF1 RAD50	6.33e-05	266	55	6	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k2_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	ATRX RSF1 CHD9 BOD1L1 MPHOSPH8 CPSF2 RRM1 CEP57 MTDH ZMYM5 ESF1 SMAD5 RAD50	6.88e-05	1459	55	13	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3	ATRX CCDC18 BOD1L1 ESF1 SMAD5 MTSS2 RAD50	1.20e-04	432	55	7	Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	ATRX KDM5A CHD9 BOD1L1 LSM14A ESF1 MTSS2 RAD50	1.38e-04	595	55	8	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	ATRX KDM5A CCDC18 SYCP1 CHD9 MPHOSPH8 ANKRD12 CEP57 ESF1	1.56e-04	776	55	9	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000	UTP18 BAZ2A CCDC18 SYCP1 CHD1L ANKRD12 ZMYM5 ESF1 RAD50	2.15e-04	810	55	9	gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000	UTP18 CCDC18 CHD1L ZMYM5 ESF1 RAD50	2.16e-04	333	55	6	gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	ATRX KDM5A CHD9 BOD1L1 MPHOSPH8 ZMYM5 ESF1 SMAD5 ENOX2 RAD50	3.47e-04	1060	55	10	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	FAM133B RSF1 CCDC18 MPHOSPH8 CEP57 ESF1 UTP14C	4.27e-04	532	55	7	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_500	ATRX KDM5A CCDC18 SYCP1 ANKRD12 ESF1	4.49e-04	382	55	6	gudmap_developingGonad_e14.5_ ovary_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#3_top-relative-expression-ranked_100	MYH11 ANKRD1	5.88e-04	14	55	2	gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_100_k3
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	ATRX KDM5A RSF1 CCDC18 BOD1L1 MPHOSPH8 ANKRD12 DDX27 ESF1 RAD50	7.43e-14	197	57	10	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	ATRX MYCBP2 RSF1 CCDC18 BOD1L1 ANKRD12 SMAD5 RAD50	1.68e-10	198	57	8	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	RALA ATRX RSF1 BOD1L1 ANKRD12 MTDH RAD50	6.53e-09	199	57	7	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX MYCBP2 CHD9 BOD1L1 TOP2B SEPTIN6	1.23e-07	182	57	6	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX MYCBP2 CHD9 BOD1L1 TOP2B SEPTIN6	1.23e-07	182	57	6	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARP1 ATRX MYCBP2 RSF1 CHD9 TOP2B	1.36e-07	185	57	6	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARP1 ATRX MTSS1 CCDC18 CHD9 TOP2B	1.80e-07	194	57	6	8ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCell	(04)_Interm._basal>secr.-(2)_GFP_FOXI1\|(04)_Interm._basal>secr. / shred by cell type by condition	RALA ATRX RSF1 BOD1L1 ANKRD12 RAD50	2.09e-07	199	57	6	53ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M\|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.	MYCBP2 MTSS1 BOD1L1 LSM14A ANKRD12 SH3RF3	2.09e-07	199	57	6	b2d7dea11207cca63d688f8051143850b29dbdf0
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	ATRX RSF1 BOD1L1 ANKRD12 SMAD5 RAD50	2.09e-07	199	57	6	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAM186A CCDC18 DIAPH3 RRM1 DEPDC1B	3.16e-06	177	57	5	3081ce5fc66a1bb833719d6c0e0a6fc7115eeb91
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX MYCBP2 MTSS1 CHD9 TOP2B	3.62e-06	182	57	5	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX MYCBP2 RSF1 CHD9 TOP2B	3.82e-06	184	57	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARP1 ATRX MTSS1 BOD1L1 TOP2B	4.70e-06	192	57	5	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	cycling_basal_cell\|World / shred by cell class for nasal brushing	ATRX CCDC18 DIAPH3 RRM1 DEPDC1B	5.19e-06	196	57	5	aa7bac70a2fe4a3cb28d89fa1a87c68c2ead1349
ToppCell	(3)_MNP-(3)_Macrophage_Dividing\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	ARHGEF28 ATRX DIAPH3 RRM1 DEPDC1B	5.32e-06	197	57	5	048bc4f8fd5d4f394e2384700640f72042336597
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35\|World / Primary Cells by Cluster	ATRX MTSS1 RSF1 CHD9 TOP2B	5.46e-06	198	57	5	de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	ATRX RSF1 BOD1L1 ANKRD12 RAD50	5.59e-06	199	57	5	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	(00)_Basal-(2)_GFP_FOXI1\|(00)_Basal / shred by cell type by condition	ATRX RSF1 BOD1L1 ANKRD12 RAD50	5.59e-06	199	57	5	19674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	ATRX RSF1 BOD1L1 ANKRD12 RAD50	5.59e-06	199	57	5	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	ATRX RSF1 BOD1L1 ANKRD12 RAD50	5.59e-06	199	57	5	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FAM133B ATRX MYCBP2 BOD1L1 ANKRD12	5.73e-06	200	57	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	RSF1 BOD1L1 ANKRD12 RAD50	2.95e-05	138	57	4	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 ANKRD1 TRDN DEPDC1B	6.06e-05	166	57	4	9a341dc7b756252caeaac1e934384911c880a634
ToppCell	Dividing_Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ARHGEF28 ATRX DIAPH3 DEPDC1B	6.06e-05	166	57	4	c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 ANKRD1 TRDN DEPDC1B	6.06e-05	166	57	4	390cf5e56b72fcaf3b8520930bd35a3e3e173711
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCDC18 CHD1L DIAPH3 CEP57	6.20e-05	167	57	4	754e6412d3b9cc0b126e59593df2f5956b4712ef
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 ANKRD1 TRDN DEPDC1B	6.50e-05	169	57	4	a6a5b00912b653fad2ca7f096deaf35c9ef85e5b
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 ANKRD1 TRDN DEPDC1B	6.50e-05	169	57	4	88aa2246ede582c2e11de63228d76f520889ecb3
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 ANKRD1 TRDN DEPDC1B	6.50e-05	169	57	4	42a9b8c77d2a4d68b01e4db38f8a1af53c9c814f
ToppCell	droplet-Fat-Mat-18m-Lymphocytic-lymphocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKD2L2 CEP57 SEPTIN6 UTP14C	6.96e-05	172	57	4	226de1a5d4a360d3ae01b0235fea19521ec623a0
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYH11 NF1 TCERG1L PKD2L2	7.77e-05	177	57	4	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	(01)_Cycling_Basal_(homeostasis)\|World / shred by cell type and Timepoint	CCDC18 DIAPH3 RRM1 DEPDC1B	7.77e-05	177	57	4	05c57578142a6662f18b294d5cc11e6efd6b0f8e
ToppCell	P15-Endothelial-proliferative_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CCDC18 DIAPH3 RRM1 DEPDC1B	8.47e-05	181	57	4	0c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCell	P15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CCDC18 DIAPH3 RRM1 DEPDC1B	8.47e-05	181	57	4	f83565f09dd971c5cad2704a4a86bca0accd955e
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DIAPH3 FAM228A RRM1 DEPDC1B	8.47e-05	181	57	4	73b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCell	Brain_organoid-organoid_Kanton_Nature\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	BAZ2A CHD9 ICE1 SEPTIN6	9.22e-05	185	57	4	857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell	3'_v3-blood-Lymphocytic_T_CD4/8-lo\|blood / Manually curated celltypes from each tissue	PARP1 DIAPH3 RRM1 DEPDC1B	9.22e-05	185	57	4	df85ff34b796b403f2d0741771e9592e03657f6a
ToppCell	3'_v3-blood-Lymphocytic_T_CD4/8-lo-Cycling_T\|blood / Manually curated celltypes from each tissue	PARP1 DIAPH3 RRM1 DEPDC1B	9.81e-05	188	57	4	714ccbcf826f26d39757931a3b8abbd952f4cddc
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX CHD9 MTDH TOP2B	1.04e-04	191	57	4	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	Dividing_Macrophages-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	ATRX DIAPH3 RRM1 DEPDC1B	1.04e-04	191	57	4	3e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX CHD9 MTDH TOP2B	1.04e-04	191	57	4	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	(3)_Macrophage_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ARHGEF28 ATRX DIAPH3 DEPDC1B	1.04e-04	191	57	4	b42f0b89bb94fd43786ff50f1caeb3ebfbbb43fd
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX CHD9 MTDH TOP2B	1.04e-04	191	57	4	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	KDM5A CCDC18 BOD1L1 ANKRD12	1.06e-04	192	57	4	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 CCDC18 DIAPH3 RRM1	1.09e-04	193	57	4	a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-4\|World / Primary Cells by Cluster	MYCBP2 MTSS1 CHD9 ANKRD12	1.09e-04	193	57	4	2eb6e4cff4fe3ce564c1581f6f7df4834895aaa9
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC18 DIAPH3 RRM1 DEPDC1B	1.09e-04	193	57	4	e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PARP1 DIAPH3 DEPDC1B SEPTIN6	1.09e-04	193	57	4	b835d28de9daeec5213172c96f62b332cda53bb5
ToppCell	10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PARP1 CHD9 TOP2B SEPTIN6	1.11e-04	194	57	4	f64da5f62e29253d60b9546edf734ba5c17daae1
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC18 DIAPH3 RRM1 DEPDC1B	1.11e-04	194	57	4	1a2090e997c70433d07f56bf7cb0a50c4151118c
ToppCell	(1)_T_cells_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ATRX DIAPH3 RRM1 DEPDC1B	1.11e-04	194	57	4	8f313071933451780309d2174ed27d8cdc734343
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	ATRX DIAPH3 RRM1 DEPDC1B	1.11e-04	194	57	4	4d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCell	(7)_Epithelial-J_(AT1-AT2_progenitors)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ATRX DIAPH3 RRM1 DEPDC1B	1.13e-04	195	57	4	70e6b58c502a2abeb4e36bed179020c675468bd4
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PARP1 DIAPH3 DEPDC1B SEPTIN6	1.13e-04	195	57	4	67670d16ddd5d5ab7bc2254df329f5a7b2581556
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	CCDC18 DIAPH3 RRM1 DEPDC1B	1.13e-04	195	57	4	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CCDC18 DIAPH3 RRM1 DEPDC1B	1.13e-04	195	57	4	926eb3fc5d028be936885bea0654a77db3107234
ToppCell	(1)_T_cells-(1)_T_cells_Dividing\|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	ATRX DIAPH3 RRM1 DEPDC1B	1.13e-04	195	57	4	cf00a0b4f341f0487d5b37810abe2952fdd3f6f2
ToppCell	BLOOD--(1)_Activated_T_cells\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PARP1 ATRX DIAPH3 DEPDC1B	1.13e-04	195	57	4	45515d5da8a8c8242eb70a1bea24fe44eca5407b
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PARP1 DIAPH3 DEPDC1B SEPTIN6	1.13e-04	195	57	4	23dc2f8a3a038195a31feee7e3a51094a7a7c23e
ToppCell	(4)_B_Hypermutation\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ATRX DIAPH3 RRM1 DEPDC1B	1.13e-04	195	57	4	54d2acaff6be6b5604591bdbd7d769ac3e74f223
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX MYCBP2 CHD9 TRDN	1.13e-04	195	57	4	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	CV-Moderate-6\|CV / Virus stimulation, Condition and Cluster	ATRX MTSS1 BOD1L1 RAD50	1.15e-04	196	57	4	7bced0cc2112697593c478fa291b8ed3941fb811
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CCDC18 DIAPH3 RRM1 DEPDC1B	1.15e-04	196	57	4	73f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCell	myeloid-pro-pDC\|myeloid / Lineage and Cell class	PARP1 DIAPH3 DEPDC1B SEPTIN6	1.15e-04	196	57	4	70daf4fabb68aecc5cc9f03d6f6495dd29b74a16
ToppCell	wk_15-18-Hematologic_Lymphocytic-B-Large_pre-B\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PARP1 RRM1 DEPDC1B SEPTIN6	1.17e-04	197	57	4	7e0834b3947031bf244a10624dcf3f2095c79368
ToppCell	10x5'-GI_large-bowel-Lymphocytic_B-GC_B_(I)\|GI_large-bowel / Manually curated celltypes from each tissue	PARP1 DIAPH3 RRM1 DEPDC1B	1.17e-04	197	57	4	80a0cfbd454409594effead7082586b06c2f411a
ToppCell	Mild\|World / Condition, Lineage, Cell class and cell subclass	ATRX SEPTIN6 DOP1A RAD50	1.17e-04	197	57	4	476b0d0389f9fcd4614f6bb1f494281f467f6730
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FAM133B PARP1 TOP2B SEPTIN6	1.20e-04	198	57	4	5f465cf5c7493e32d9afe9e9d05757d0a95acc33
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FAM133B PARP1 TOP2B SEPTIN6	1.20e-04	198	57	4	77ce3fe1ab161c0faf8987e73a64ab61294b9255
ToppCell	(4)_B_cells-(4)_B_Hypermutation\|(4)_B_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ATRX DIAPH3 RRM1 DEPDC1B	1.20e-04	198	57	4	8be724a49b4c911d68c3e82fb75e96722d0eaa03
ToppCell	cycling_basal_cell\|World / shred by cell class for bronchial biopsy	CCDC18 DIAPH3 RRM1 DEPDC1B	1.20e-04	198	57	4	d5306121a75c5eb37d62c353799a98e6ba5ab63f
ToppCell	(0)_NK_cells-(0)_NK_Dividing\|(0)_NK_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	ATRX DIAPH3 RRM1 DEPDC1B	1.20e-04	198	57	4	d9cdbc7d420472cb1ffb36ad9c8e53a61b7dbdeb
ToppCell	(3)_DC_Monocyte_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ATRX DIAPH3 RRM1 DEPDC1B	1.20e-04	198	57	4	e2b89f6d7c0007ccab62495cd543fe0e5513a9a4
ToppCell	cycling_basal_cell\|World / shred by cell class for turbinate	ATRX DIAPH3 RRM1 DEPDC1B	1.20e-04	198	57	4	e86c1224f5b0890a50a25257628e90c790aae7cd
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PARP1 DIAPH3 RRM1 DEPDC1B	1.20e-04	198	57	4	281fc2536cdc4c717b30de156e563c0e4baba99d
ToppCell	(1)_T_cell_dividing\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ATRX DIAPH3 RRM1 DEPDC1B	1.20e-04	198	57	4	dac3a16e3a070a37f4d0ea37633c23fdc8a9c70a
ToppCell	(0)_NK_dividing\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ATRX DIAPH3 RRM1 DEPDC1B	1.20e-04	198	57	4	c5336d9b802393d6fd6f8446ea4bb6befeb97bfd
ToppCell	(0)_NK_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ATRX DIAPH3 RRM1 DEPDC1B	1.20e-04	198	57	4	5ebb4965b723302152b42bfaf48bb77a57dd02c5
ToppCell	15-Airway-Mesenchymal-Mesenchyme_RSPO2+\|Airway / Age, Tissue, Lineage and Cell class	CCDC18 DIAPH3 RRM1 DEPDC1B	1.22e-04	199	57	4	5c8b847b794b3e88722f5b841f2539a27251106c
ToppCell	10x5'v1-week_12-13-Lymphocytic_B-B_lineage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PARP1 RRM1 TOP2B SEPTIN6	1.22e-04	199	57	4	ea75804c34989c99aab542e6d72617ed144819b6
ToppCell	10x5'v1-week_12-13-Lymphocytic_B-B_lineage-pre_pro_B_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PARP1 RRM1 TOP2B SEPTIN6	1.22e-04	199	57	4	5478b78349b5d8d57f30bb650dcbd5fdb84283d6
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	RSF1 BOD1L1 ANKRD12 RAD50	1.22e-04	199	57	4	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	10x5'v1-week_12-13-Lymphocytic_B\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PARP1 RRM1 TOP2B SEPTIN6	1.22e-04	199	57	4	713dfd8552635645db5e0b5721c64e5c9b4aa06c
ToppCell	(2)_B_cell-(24)_B_cell_cycling\|(2)_B_cell / shred on Cell_type and subtype	ATRX DIAPH3 RRM1 DEPDC1B	1.22e-04	199	57	4	d5a9a8a71c4de8cbcef947943f60838731bc640b
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B-B_lineage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PARP1 RRM1 TOP2B SEPTIN6	1.22e-04	199	57	4	fe3b7d540a644dfc6beea171c809b4d1ba4e188f
ToppCell	megakaryocytic-CD34+_Megakaryoblast\|megakaryocytic / Lineage and Cell class	FAM133B PARP1 MYCBP2 MTDH	1.22e-04	199	57	4	99a65887d3c8a2cde26693dd74404b101bba9d58
ToppCell	NS-critical-d_16-33-Lymphoid-NKT-proliferating\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PARP1 DIAPH3 RRM1 DEPDC1B	1.22e-04	199	57	4	31b144bb209c629e12156f4d9c9cec79baffffb9
ToppCell	(1)_T_cells-(1)_T_cell_dividing\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ATRX DIAPH3 RRM1 DEPDC1B	1.22e-04	199	57	4	33afdd1b1b951b360ababf440bc556fd9e1c1db2
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PARP1 RRM1 TOP2B SEPTIN6	1.22e-04	199	57	4	cdee798e3586e4e7a15de598239090a85752ea1e
ToppCell	Striatum-Neuronal\|Striatum / BrainAtlas - Mouse McCarroll V32	MYCBP2 ATP6V1D MPHOSPH8 ANKRD12	1.24e-04	200	57	4	c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	CCDC18 DIAPH3 RRM1 DEPDC1B	1.24e-04	200	57	4	cea58274efbe7f9e3c3ef9fbb768ebfb917e21d9
ToppCell	Non-neuronal-Dividing-IPC\|World / Primary Cells by Cluster	CCDC18 DIAPH3 RRM1 DEPDC1B	1.24e-04	200	57	4	971533181daa1bfac1f1b8c507d2013f891f9078
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	PARP1 DIAPH3 RRM1 CEP57	1.24e-04	200	57	4	5f2fbd789cc16af411a01c3199583888b260ae91
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCDC18 DIAPH3 RRM1 DEPDC1B	1.24e-04	200	57	4	63f9481059be608ddc9fe9c7a8f8503fce9755dd
ToppCell	10x3'2.3-week_14-16-Lymphocytic_B\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PARP1 RRM1 TOP2B SEPTIN6	1.24e-04	200	57	4	19a4213f180ac2d29625d140b602a93a74ab3fdd
ToppCell	Biopsy_Control_(H.)-Immune-Proliferating_Macrophages\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	CCDC18 DIAPH3 RRM1 DEPDC1B	1.24e-04	200	57	4	ce9fad55f779afd3d6c5a9c5a15e2d9f548b7c7e
ToppCell	(0)_NK_cells-(0)_NK_dividing\|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ATRX DIAPH3 RRM1 DEPDC1B	1.24e-04	200	57	4	1a630bb327070ffcb111ec36bd8fd4be3627ca2a
ToppCell	10x3'2.3-week_14-16-Lymphocytic_B-B_lineage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PARP1 RRM1 TOP2B SEPTIN6	1.24e-04	200	57	4	0fd9a8730b7dc461ddf4586899d363541e72d8ba
ToppCell	(3)_MNP-(3)_DC_Monocyte_Dividing\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	ATRX DIAPH3 RRM1 DEPDC1B	1.24e-04	200	57	4	d94fe9bd6ee7c1fed14666f24de41bda014e299b
Drug	Diphenhydramine hydrochloride [147-24-0]; Down 200; 13.8uM; MCF7; HT_HG-U133A	NF1 ATRX KDM5A CEP57 ZMYM5 SMAD5	7.38e-06	191	56	6	6020_DN
Drug	Acenocoumarol [152-72-7]; Down 200; 11.4uM; PC3; HT_HG-U133A	ATRX KDM5A ATP6V1D LSM14A ZMYM5 SMAD5	9.07e-06	198	56	6	5878_DN
Drug	testosterone enanthate	MYH11 ATRX KDM5A SYCP1 CEP57 ZMYM5 ESF1 SMAD5 RAD50	1.03e-05	575	56	9	ctd:C004648
Disease	intellectual developmental disorder with ocular anomalies and distinctive facial features (implicated_via_orthology)	MTSS1 MTSS2	3.41e-06	2	55	2	DOID:0081301 (implicated_via_orthology)
Disease	Mental Retardation, Psychosocial	PARP1 NF1 KDM5A LETM1	1.33e-04	139	55	4	C0025363
Disease	Profound Mental Retardation	PARP1 NF1 KDM5A LETM1	1.33e-04	139	55	4	C0020796
Disease	Mental deficiency	PARP1 NF1 KDM5A LETM1	1.33e-04	139	55	4	C0917816
Disease	intellectual disability (implicated_via_orthology)	ATRX KDM5A BOD1L1	3.76e-04	75	55	3	DOID:1059 (implicated_via_orthology)
Disease	malignant astrocytoma (is_marker_for)	NF1 ATRX	8.42e-04	23	55	2	DOID:3069 (is_marker_for)
Disease	blood chromium measurement	TCERG1L TRDN	1.08e-03	26	55	2	EFO_0007579
Disease	Intellectual Disability	RALA PARP1 NF1 KDM5A LETM1	1.46e-03	447	55	5	C3714756
Disease	emphysema imaging measurement	MYCBP2 CCDC18 ANKRD12	2.58e-03	146	55	3	EFO_0007626
Disease	high grade glioma (is_implicated_in)	NF1 ATRX	2.80e-03	42	55	2	DOID:3070 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
ADKKQKRKEKKTADL	FAM228A	141	Q86W67
LEKEKLKKEAAKKLE	CPSF2	396	Q9P2I0
KSEKQREAELKKKKL	ANKRD1	61	Q15327
ETKSLKQKEAKKKSK	BAZ2A	741	Q9UIF9
EKQKLEKQKKELKAT	CEP57	426	Q86XR8
EKQKKELKATKKTLD	CEP57	431	Q86XR8
SKRSKNIKKKLKEEQ	C19orf18	181	Q8NEA5
TDAKLSNKEKKKKLK	DEPDC1B	461	Q8WUY9
KLARKKDDDKKKSSN	DOP1A	1301	Q5JWR5
EKKSKLEKNIKDDKS	ANKRD12	721	Q6UB98
KKKIKELKFLDSKIA	DIAPH3	706	Q9NSV4
KKRKTEDKEAKSGKL	DDX27	126	Q96GQ7
EDSKEKNGKKKRKSL	RALA	181	P11233
KKKKVAGQLEKLKED	RBM19	116	Q9Y4C8
KLKSTESELKKKEKR	RAD50	711	Q92878
KEKDKDSKLEKALKA	PARP1	226	P09874
KSKTKSKDAKDKEKL	ARHGEF28	636	Q8N1W1
ESLSDKIQKKKKKIL	C20orf96	256	Q9NUD7
EEEALQKKFNKLKKK	NELFE	11	P18615
KKKEAELEKLKDDKL	ENOX2	476	Q16206
EKSLKSLKDKNKKLE	LETM1	121	O95202
QKKLKESVKKEAAKD	DUOX2	631	Q9NRD8
KKKTQTKKEIDSKNL	ESF1	96	Q9H501
DSKNLVEKKKETKKA	ESF1	106	Q9H501
IKKKSSDTLKLQKKA	MTSS2	136	Q765P7
EIKKKSSDTLKLQKK	MTSS1	136	O43312
NKLKLKEDKLEKQEK	LSM14A	316	Q8ND56
KKLKLGADKSKELNK	KDM5A	1536	P29375
EKNLVKLAKCLKKEK	PIPSL	606	A2A3N6
LEKKVALSKKRKKDS	BOD1L1	566	Q8NFC6
SKKIRDKTSKKKDEL	ATRX	1046	P46100
DKDSKKTKTCSKLKE	CHD9	576	Q3L8U1
SDAQKKKLEAKVKKL	ICE1	126	Q9Y2F5
ESDSKDSLKKKKKSK	FAM133B	151	Q5BKY9
LEGNKEKFEKQLKKK	CCDC18	746	Q5T9S5
KLKKKEKEKAQLAAE	FAM193B	501	Q96PV7
EEGLKKIFLAAKKKK	CHD1L	821	Q86WJ1
SEEQKKKNRKKLSEK	MTDH	111	Q86UE4
TSFLDEKKKQKKKIL	FAM186A	181	A6NE01
VTEKKNKKLKKASAE	C7orf50	11	Q9BRJ6
KKKDSKKSKANLLER	RSF1	996	Q96T23
LSKKKKTKREQLSEK	SLC13A4	346	Q9UKG4
DDLKKKKAKAGKLKD	MPHOSPH8	166	Q99549
SKLSKDNLKKRLKEE	UTP18	171	Q9Y5J1
ADASKKLLKKKKGDL	TOP2B	1251	Q02880
AVLKKKECEKENKKS	MYCBP2	3191	O75592
QDEKKKLEDKKKSLD	SEPTIN6	376	Q14141
AEKAVDALVKKLKKK	SMAD5	31	Q99717
TKSLKQKDKKLKEIL	MYH11	1841	P35749
KEEYKEKKSKLLLAK	TCERG1L	506	Q5VWI1
EKKSKLLLAKEEFKK	TCERG1L	511	Q5VWI1
KKGKAKKALKEFEQL	UTP14C	256	Q5TAP6
TLNKEKLKDKEKVSK	RRM1	751	P23921
EKKSEKKEKKSGLLK	SH3RF3	711	Q8TEJ3
AKENTATLKEKKDKK	SYCP1	781	Q15431
QEKKKILKEKSEKDL	ATP6V1D	206	Q9Y5K8
LLNKATVKEKKENKK	NF1	1376	P21359
FRLKKAQKDEDKKTK	PKD2L2	526	Q9NZM6
KKAKTAEKSEEKTKK	TRDN	206	Q13061
SKLKSDLKKNKAIDA	ZMYM5	636	Q9UJ78
KEKGKENNKLEVLKK	TBRG1	141	Q3YBR2
ENNKLEVLKKTCKKK	TBRG1	146	Q3YBR2