Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

SELE VLDLR FAT4 PAMR1 NOTCH2NLA RET ADGRE2 VWCE NOTCH2NLC LDLR SLIT2 SCUBE1 OIT3 DST NOTCH2NLB SLIT1 LRP2 LRP4 HABP2 ADGRE1 LTBP4 AGRN NOTCH2 NOTCH3

2.86e-1374910124GO:0005509
GeneOntologyMolecularFunctionextracellular matrix structural constituent

FRAS1 LAMB1 LAMC1 TECTA SLIT2 LTBP4 AGRN MUC6

5.09e-061881018GO:0005201
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

SEMA5A SLIT2 SLIT1 AGRN

1.33e-05291014GO:0043395
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

VLDLR LDLR LRP2

6.71e-05161013GO:0005041
GeneOntologyMolecularFunctionproteoglycan binding

SEMA5A SLIT2 SLIT1 AGRN

1.28e-04511014GO:0043394
GeneOntologyMolecularFunctionvery-low-density lipoprotein particle receptor activity

VLDLR LDLR

1.51e-0441012GO:0030229
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

VLDLR LDLR LRP2

1.56e-04211013GO:0030228
GeneOntologyMolecularFunctionglycosaminoglycan binding

SEMA5A ADGRE2 SLIT2 SLIT1 HABP2 LTBP4 AGRN

4.26e-042681017GO:0005539
GeneOntologyMolecularFunctionlaminin binding

SLIT2 AGRN LRRC15

6.71e-04341013GO:0043236
GeneOntologyMolecularFunctionchondroitin sulfate binding

ADGRE2 AGRN

1.35e-03111012GO:0035374
GeneOntologyMolecularFunctionRoundabout binding

SLIT2 SLIT1

1.62e-03121012GO:0048495
GeneOntologyMolecularFunctionclathrin heavy chain binding

PLK2 LDLR

1.62e-03121012GO:0032050
GeneOntologyMolecularFunctionstructural molecule activity

FRAS1 KRTAP29-1 LAMB1 LAMC1 TECTA CLDN23 SLIT2 DST KRT40 LTBP4 AGRN MUC6

1.79e-0389110112GO:0005198
GeneOntologyMolecularFunctionglycosphingolipid binding

LAMB1 LAMC1

1.91e-03131012GO:0043208
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

VLDLR WNT3 TRPC5 LAMB1 LAMC1 SEMA5A RET TECTA SLIT2 DACT1 GRXCR2 DST TNN SLIT1 LRP2 LRP4 AGRN NOTCH2 NOTCH3

2.00e-097489819GO:0048667
GeneOntologyBiologicalProcessneuron projection development

VLDLR FAT4 PLK2 WNT3 TRPC5 LAMB1 LAMC1 SEMA5A GRN RET TECTA SLIT2 DACT1 GRXCR2 DST TNN SLIT1 MYLIP LRP2 LRP4 AGRN NOTCH2 NOTCH3

2.48e-0812859823GO:0031175
GeneOntologyBiologicalProcessaxon development

WNT3 TRPC5 LAMB1 LAMC1 SEMA5A GRN RET SLIT2 DST TNN SLIT1 LRP2 LRP4 AGRN NOTCH2 NOTCH3

5.72e-086429816GO:0061564
GeneOntologyBiologicalProcessaxonogenesis

WNT3 TRPC5 LAMB1 LAMC1 SEMA5A RET SLIT2 DST TNN SLIT1 LRP2 LRP4 AGRN NOTCH2 NOTCH3

7.02e-085669815GO:0007409
GeneOntologyBiologicalProcessaxon guidance

WNT3 LAMB1 LAMC1 SEMA5A RET SLIT2 SLIT1 LRP2 AGRN NOTCH2 NOTCH3

1.12e-072859811GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

WNT3 LAMB1 LAMC1 SEMA5A RET SLIT2 SLIT1 LRP2 AGRN NOTCH2 NOTCH3

1.16e-072869811GO:0097485
GeneOntologyBiologicalProcessneuron projection morphogenesis

VLDLR WNT3 TRPC5 LAMB1 LAMC1 SEMA5A RET SLIT2 DACT1 DST TNN SLIT1 LRP2 LRP4 AGRN NOTCH2 NOTCH3

2.14e-078029817GO:0048812
GeneOntologyBiologicalProcessneuron development

VLDLR FAT4 PLK2 WNT3 TRPC5 LAMB1 LAMC1 SEMA5A GRN RET TECTA SLIT2 DACT1 GRXCR2 DST TNN SLIT1 MYLIP LRP2 LRP4 AGRN NOTCH2 NOTCH3

2.61e-0714639823GO:0048666
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

VLDLR WNT3 TRPC5 LAMB1 LAMC1 SEMA5A RET SLIT2 DACT1 DST TNN SLIT1 LRP2 LRP4 AGRN NOTCH2 NOTCH3

2.87e-078199817GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

VLDLR WNT3 TRPC5 LAMB1 LAMC1 SEMA5A RET SLIT2 DACT1 DST TNN SLIT1 LRP2 LRP4 AGRN NOTCH2 NOTCH3

3.24e-078269817GO:0048858
GeneOntologyBiologicalProcessnegative regulation of neurogenesis

WNT3 TRPC5 SEMA5A LDLR CASZ1 SLIT2 SLIT1 LRP4

1.73e-06173988GO:0050768
GeneOntologyBiologicalProcessnegative regulation of nervous system development

WNT3 TRPC5 SEMA5A LDLR CASZ1 SLIT2 SLIT1 LRP4

2.73e-06184988GO:0051961
GeneOntologyBiologicalProcesscell morphogenesis

VLDLR WNT3 TRPC5 LAMB1 LAMC1 SEMA5A RET TECTA SLIT2 DACT1 GRXCR2 DST TNN SLIT1 LRP2 LRP4 AGRN NOTCH2 NOTCH3

2.93e-0611949819GO:0000902
GeneOntologyBiologicalProcessaxon extension involved in axon guidance

WNT3 SEMA5A SLIT2 SLIT1

3.28e-0622984GO:0048846
GeneOntologyBiologicalProcessneuron projection extension involved in neuron projection guidance

WNT3 SEMA5A SLIT2 SLIT1

3.28e-0622984GO:1902284
GeneOntologyBiologicalProcesskidney development

PCSK5 FAT4 FRAS1 KLF15 RET SLIT2 LRP2 LRP4 NOTCH2 NOTCH3

1.10e-053729810GO:0001822
GeneOntologyBiologicalProcessnegative regulation of axonogenesis

WNT3 SEMA5A SLIT2 SLIT1 LRP4

1.14e-0562985GO:0050771
GeneOntologyBiologicalProcessrenal system development

PCSK5 FAT4 FRAS1 KLF15 RET SLIT2 LRP2 LRP4 NOTCH2 NOTCH3

1.52e-053869810GO:0072001
GeneOntologyBiologicalProcessnegative regulation of axon extension involved in axon guidance

WNT3 SEMA5A SLIT1

1.67e-0511983GO:0048843
GeneOntologyBiologicalProcessnegative regulation of axon extension

WNT3 SEMA5A SLIT2 SLIT1

3.12e-0538984GO:0030517
GeneOntologyBiologicalProcessregulation of neuron projection development

VLDLR WNT3 TRPC5 SEMA5A GRN RET SLIT2 TNN SLIT1 MYLIP LRP4 AGRN

3.32e-056129812GO:0010975
GeneOntologyBiologicalProcesspositive regulation of integrin-mediated signaling pathway

PCSK5 LAMB1 LAMC1

3.64e-0514983GO:2001046
GeneOntologyBiologicalProcessregulation of axonogenesis

WNT3 TRPC5 SEMA5A RET SLIT2 SLIT1 LRP4

3.68e-05192987GO:0050770
GeneOntologyBiologicalProcessregulation of nervous system development

WNT3 TRPC5 SEMA5A ADGRE2 LDLR CASZ1 SLIT2 SLIT1 LRP2 LRP4 AGRN NOTCH2

4.07e-056259812GO:0051960
GeneOntologyBiologicalProcessnegative regulation of cell development

WNT3 TRPC5 SEMA5A LDLR IFNA2 CASZ1 SLIT2 SLIT1 LRP4

4.69e-05353989GO:0010721
GeneOntologyBiologicalProcessNotch signaling pathway

FAT4 NOTCH2NLA NOTCH2NLC OVOL2 NOTCH2NLB NOTCH2 NOTCH3

6.48e-05210987GO:0007219
GeneOntologyBiologicalProcesschemorepulsion involved in embryonic olfactory bulb interneuron precursor migration

SLIT2 SLIT1

6.68e-053982GO:0021834
GeneOntologyBiologicalProcessregulation of axon extension involved in axon guidance

WNT3 SEMA5A SLIT1

6.74e-0517983GO:0048841
GeneOntologyBiologicalProcesscerebral cortex development

FAT4 NOTCH2NLA LAMB1 NOTCH2NLC SLIT2 NOTCH2NLB

7.26e-05147986GO:0021987
GeneOntologyBiologicalProcessforebrain development

FAT4 NOTCH2NLA LAMB1 SEMA5A NOTCH2NLC SLIT2 NOTCH2NLB SLIT1 LRP2 NOTCH3

1.11e-044899810GO:0030900
GeneOntologyBiologicalProcessnegative regulation of cell projection organization

WNT3 TRPC5 SEMA5A SLIT2 SLIT1 MYLIP LRP4

1.24e-04233987GO:0031345
GeneOntologyBiologicalProcessnegative regulation of chemotaxis

WNT3 SEMA5A SLIT2 SLIT1

1.26e-0454984GO:0050922
GeneOntologyBiologicalProcessdorsal/ventral axon guidance

SLIT2 SLIT1

1.33e-044982GO:0033563
GeneOntologyBiologicalProcessregulation of axon extension

WNT3 TRPC5 SEMA5A SLIT2 SLIT1

1.39e-04104985GO:0030516
GeneOntologyBiologicalProcessnegative regulation of neuron projection development

WNT3 SEMA5A SLIT2 SLIT1 MYLIP LRP4

1.56e-04169986GO:0010977
GeneOntologyBiologicalProcessregulation of neurogenesis

WNT3 TRPC5 SEMA5A LDLR CASZ1 SLIT2 SLIT1 LRP2 LRP4 NOTCH2

1.69e-045159810GO:0050767
GeneOntologyBiologicalProcessregulation of integrin-mediated signaling pathway

PCSK5 LAMB1 LAMC1

1.72e-0423983GO:2001044
GeneOntologyBiologicalProcessepithelium development

FAT4 FRAS1 KLF15 LAMC1 SEMA5A RET TECTA LCE2D OVOL2 SLIT2 DACT1 GRXCR2 SCUBE1 KRT40 LRP2 LRP4 USH2A NOTCH2

1.73e-0414699818GO:0060429
GeneOntologyBiologicalProcesslysosomal protein catabolic process

GRN LDLR LRP2

1.96e-0424983GO:1905146
GeneOntologyBiologicalProcessembryonic olfactory bulb interneuron precursor migration

SLIT2 SLIT1

2.21e-045982GO:0021831
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LDLR LRP2

2.21e-045982GO:1905167
GeneOntologyBiologicalProcessnegative regulation of cell differentiation

WNT3 TRPC5 SEMA5A LDLR IFNA2 CASZ1 OVOL2 SLIT2 TNN SLIT1 LRP4 USH2A NOTCH3

2.52e-048759813GO:0045596
GeneOntologyBiologicalProcessappendage morphogenesis

PCSK5 FRAS1 WNT3 EVX2 LRP4 NOTCH2

2.55e-04185986GO:0035107
GeneOntologyBiologicalProcesslimb morphogenesis

PCSK5 FRAS1 WNT3 EVX2 LRP4 NOTCH2

2.55e-04185986GO:0035108
GeneOntologyBiologicalProcessregulation of extent of cell growth

WNT3 TRPC5 SEMA5A SLIT2 SLIT1

2.92e-04122985GO:0061387
GeneOntologyBiologicalProcessanimal organ morphogenesis

FAT4 FRAS1 WNT3 LAMB1 LAMC1 TECTA CASZ1 OVOL2 SLIT2 GRXCR2 SLIT1 LRP2 LRP4 USH2A MEGF11 NOTCH2

3.04e-0412699816GO:0009887
GeneOntologyBiologicalProcessprotein catabolic process in the vacuole

GRN LDLR LRP2

3.13e-0428983GO:0007039
GeneOntologyBiologicalProcessglomerulus vasculature morphogenesis

NOTCH2 NOTCH3

3.31e-046982GO:0072103
GeneOntologyBiologicalProcessglomerular capillary formation

NOTCH2 NOTCH3

3.31e-046982GO:0072104
GeneOntologyBiologicalProcesshemidesmosome assembly

LAMC1 DST

3.31e-046982GO:0031581
GeneOntologyBiologicalProcessregulation of Wnt signaling pathway

MDFIC WNT3 KLF15 SEMA5A RNF43 DACT1 TNN LRP4

3.71e-04368988GO:0030111
GeneOntologyBiologicalProcessregulation of synapse assembly

VLDLR ADGRE2 SLIT2 SLIT1 LRP4 AGRN

4.08e-04202986GO:0051963
GeneOntologyBiologicalProcessrenal system vasculature morphogenesis

NOTCH2 NOTCH3

4.62e-047982GO:0061438
GeneOntologyBiologicalProcesskidney vasculature morphogenesis

NOTCH2 NOTCH3

4.62e-047982GO:0061439
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process in the vacuole

LDLR LRP2

4.62e-047982GO:1904352
GeneOntologyBiologicalProcessneuron projection extension

WNT3 TRPC5 SEMA5A SLIT2 TNN SLIT1

4.65e-04207986GO:1990138
GeneOntologyBiologicalProcessaxon extension

WNT3 TRPC5 SEMA5A SLIT2 SLIT1

4.65e-04135985GO:0048675
GeneOntologyBiologicalProcessglomerulus development

KLF15 RET NOTCH2 NOTCH3

4.97e-0477984GO:0032835
GeneOntologyBiologicalProcesscentral nervous system development

VLDLR FAT4 BRINP3 WNT3 NOTCH2NLA LAMB1 SEMA5A GRN NOTCH2NLC LDLR SLIT2 NOTCH2NLB SLIT1 LRP2 NOTCH3

5.10e-0411979815GO:0007417
GeneOntologyBiologicalProcesshair cell differentiation

LAMC1 TECTA GRXCR2 USH2A

5.22e-0478984GO:0035315
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

VLDLR WNT3 TRPC5 SEMA5A GRN RET SLIT2 TNN AGRN

5.75e-04494989GO:0031346
GeneOntologyBiologicalProcessamyloid-beta clearance by cellular catabolic process

LDLR LRP4

6.14e-048982GO:0150094
GeneOntologyBiologicalProcessnegative regulation of microglial cell activation

GRN LDLR

6.14e-048982GO:1903979
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

VLDLR WNT3 TRPC5 SEMA5A GRN RET SLIT2 TNN SLIT1 MYLIP LRP4 AGRN

6.68e-048469812GO:0120035
GeneOntologyBiologicalProcesspallium development

FAT4 NOTCH2NLA LAMB1 NOTCH2NLC SLIT2 NOTCH2NLB

6.71e-04222986GO:0021543
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

SELE PCSK5 VLDLR PLK2 WNT3 TRPC5 SEMA5A GRN RET ADGRE2 SLIT2 TNN LRP2 LRP4 ESPL1 AGRN

6.81e-0413669816GO:0051130
GeneOntologyBiologicalProcesslimb development

PCSK5 FRAS1 WNT3 EVX2 LRP4 NOTCH2

7.03e-04224986GO:0060173
GeneOntologyBiologicalProcessappendage development

PCSK5 FRAS1 WNT3 EVX2 LRP4 NOTCH2

7.03e-04224986GO:0048736
GeneOntologyBiologicalProcessregulation of cell size

WNT3 TRPC5 SEMA5A RET SLIT2 SLIT1

7.20e-04225986GO:0008361
GeneOntologyBiologicalProcessregulation of cell projection organization

VLDLR WNT3 TRPC5 SEMA5A GRN RET SLIT2 TNN SLIT1 MYLIP LRP4 AGRN

7.95e-048639812GO:0031344
GeneOntologyBiologicalProcessdigestive tract development

PCSK5 FAT4 RET OVOL2 DACT1

7.97e-04152985GO:0048565
GeneOntologyBiologicalProcesspositive regulation of nervous system development

WNT3 TRPC5 SEMA5A ADGRE2 SLIT2 LRP2 AGRN NOTCH2

8.54e-04418988GO:0051962
GeneOntologyBiologicalProcessamyloid-beta clearance

LDLR LRP2 LRP4

9.05e-0440983GO:0097242
GeneOntologyBiologicalProcesstangential migration from the subventricular zone to the olfactory bulb

SLIT2 SLIT1

9.81e-0410982GO:0022028
GeneOntologyBiologicalProcesstelencephalon development

FAT4 NOTCH2NLA LAMB1 NOTCH2NLC SLIT2 NOTCH2NLB SLIT1

1.04e-03332987GO:0021537
GeneOntologyBiologicalProcesskidney epithelium development

FAT4 KLF15 RET SLIT2 NOTCH2

1.06e-03162985GO:0072073
GeneOntologyBiologicalProcessmetanephros development

FAT4 FRAS1 RET SLIT2

1.10e-0395984GO:0001656
GeneOntologyBiologicalProcessinner ear receptor cell differentiation

FAT4 TECTA GRXCR2 USH2A

1.14e-0396984GO:0060113
GeneOntologyBiologicalProcessembryo development

PCSK5 FRAS1 WNT3 GRN RET TECTA OVOL2 SLIT2 DACT1 GRXCR2 CCDC62 LRP2 LRP4 KMT2A DISP1 NOTCH2

1.17e-0314379816GO:0009790
GeneOntologyBiologicalProcessglomerulus morphogenesis

NOTCH2 NOTCH3

1.20e-0311982GO:0072102
GeneOntologyBiologicalProcessregulation of basement membrane organization

LAMB1 LAMC1

1.20e-0311982GO:0110011
GeneOntologyBiologicalProcessolfactory bulb interneuron development

SLIT2 SLIT1

1.20e-0311982GO:0021891
GeneOntologyBiologicalProcesssynaptic assembly at neuromuscular junction

LRP4 AGRN

1.20e-0311982GO:0051124
GeneOntologyBiologicalProcessdigestive system development

PCSK5 FAT4 RET OVOL2 DACT1

1.21e-03167985GO:0055123
GeneOntologyBiologicalProcessregulation of neuron differentiation

BRINP3 TRPC5 RET CASZ1 ZFHX2 NOTCH3

1.37e-03255986GO:0045664
GeneOntologyBiologicalProcessregulation of lysosomal protein catabolic process

LDLR LRP2

1.43e-0312982GO:1905165
GeneOntologyBiologicalProcessregulation of axon guidance

SLIT2 AGRN

1.43e-0312982GO:1902667
GeneOntologyBiologicalProcesspositive regulation of skeletal muscle acetylcholine-gated channel clustering

LRP4 AGRN

1.43e-0312982GO:1904395
GeneOntologyBiologicalProcessepithelial cell differentiation involved in kidney development

FAT4 KLF15 NOTCH2

1.45e-0347983GO:0035850
GeneOntologyBiologicalProcessnephron development

FAT4 KLF15 RET NOTCH2 NOTCH3

1.46e-03174985GO:0072006
GeneOntologyBiologicalProcessregulation of plasma lipoprotein particle levels

PCSK5 VLDLR LDLR MYLIP

1.48e-03103984GO:0097006
GeneOntologyBiologicalProcessmechanoreceptor differentiation

FAT4 TECTA GRXCR2 USH2A

1.53e-03104984GO:0042490
GeneOntologyBiologicalProcesscell junction assembly

VLDLR LAMC1 ADGRE2 CLDN23 SLIT2 DST SLIT1 LRP4 AGRN

1.55e-03569989GO:0034329
GeneOntologyBiologicalProcesssubstrate-independent telencephalic tangential migration

SLIT2 SLIT1

1.68e-0313982GO:0021826
GeneOntologyBiologicalProcesssubstrate-independent telencephalic tangential interneuron migration

SLIT2 SLIT1

1.68e-0313982GO:0021843
GeneOntologyBiologicalProcessdorsal/ventral pattern formation

WNT3 OVOL2 LRP4 DISP1

1.70e-03107984GO:0009953
GeneOntologyBiologicalProcessnegative chemotaxis

SEMA5A SLIT2 SLIT1

1.84e-0351983GO:0050919
GeneOntologyBiologicalProcessnegative regulation of developmental process

PLK2 WNT3 TRPC5 SEMA5A LDLR IFNA2 CASZ1 OVOL2 SLIT2 TNN SLIT1 LRP4 USH2A NOTCH3

1.84e-0312209814GO:0051093
GeneOntologyBiologicalProcessregulation of protein catabolic process in the vacuole

LDLR LRP2

1.96e-0314982GO:1904350
GeneOntologyBiologicalProcessregionalization

PCSK5 WNT3 OVOL2 LRP2 LRP4 KMT2A DISP1 NOTCH2

2.00e-03478988GO:0003002
GeneOntologyCellularComponentextracellular matrix

FRAS1 COL20A1 WNT3 LAMB1 LAMC1 MUC5B TECTA IFNA2 SLIT2 FCGBP DST TNN USH2A LTBP4 AGRN MUC6 LRRC15

3.78e-0865610717GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

FRAS1 COL20A1 WNT3 LAMB1 LAMC1 MUC5B TECTA IFNA2 SLIT2 FCGBP DST TNN USH2A LTBP4 AGRN MUC6 LRRC15

3.96e-0865810717GO:0030312
GeneOntologyCellularComponentkeratin filament

KRTAP9-4 KRTAP10-10 KRTAP29-1 KRTAP4-16 KRTAP10-5 KRTAP1-1

1.06e-05971076GO:0045095
GeneOntologyCellularComponentcollagen-containing extracellular matrix

FRAS1 COL20A1 LAMB1 LAMC1 IFNA2 SLIT2 DST TNN USH2A LTBP4 AGRN LRRC15

1.74e-0553010712GO:0062023
GeneOntologyCellularComponentintermediate filament

KRTAP9-4 KRTAP10-10 KRTAP29-1 KRTAP4-16 KRTAP10-5 DST KRT40 KRTAP1-1

2.21e-052271078GO:0005882
GeneOntologyCellularComponentbasement membrane

FRAS1 LAMB1 LAMC1 DST USH2A AGRN

3.90e-051221076GO:0005604
GeneOntologyCellularComponentintermediate filament cytoskeleton

KRTAP9-4 KRTAP10-10 KRTAP29-1 KRTAP4-16 KRTAP10-5 DST KRT40 KRTAP1-1

6.29e-052631078GO:0045111
GeneOntologyCellularComponentlaminin-10 complex

LAMB1 LAMC1

7.76e-0531072GO:0043259
GeneOntologyCellularComponentlaminin-1 complex

LAMB1 LAMC1

7.76e-0531072GO:0005606
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMB1 LAMC1 TNN

8.42e-05171073GO:0098637
GeneOntologyCellularComponentGolgi lumen

PCSK5 WNT3 MUC5B AGRN MUC6

2.45e-041091075GO:0005796
GeneOntologyCellularComponentcell surface

SELE VLDLR ADGRE2 LDLR LY6D SLIT2 SCUBE1 TNN LRP2 LRP4 ADGRE1 AGRN NOTCH2 NOTCH3 LRRC15

5.30e-04111110715GO:0009986
GeneOntologyCellularComponentclathrin-coated pit

SELE VLDLR LDLR LRP2

7.61e-04801074GO:0005905
GeneOntologyCellularComponentlaminin complex

LAMB1 LAMC1

1.14e-03101072GO:0043256
MousePhenoabnormal ureteric bud morphology

FAT4 FRAS1 LAMC1 RET SLIT2 LRP4 NOTCH2

4.18e-0857837MP:0006032
MousePhenoabsent kidney

PCSK5 FRAS1 LAMC1 RET DACT1 LRP4

6.70e-0753836MP:0000520
MousePhenoimpaired branching involved in ureteric bud morphogenesis

FAT4 FRAS1 RET LRP4 NOTCH2

4.14e-0641835MP:0004936
MousePhenoabnormal urinary system development

FAT4 FRAS1 LAMC1 RET SLIT2 LRP4 NOTCH2

4.16e-06111837MP:0003942
MousePhenoabnormal branching involved in ureteric bud morphogenesis

FAT4 FRAS1 RET LRP4 NOTCH2

6.62e-0645835MP:0010981
MousePhenoabnormal kidney development

FAT4 FRAS1 LAMC1 RET SLIT2 LRP4

1.84e-0593836MP:0000527
MousePhenosingle kidney

FRAS1 LAMC1 RET DACT1 LRP4

2.99e-0561835MP:0003604
MousePhenolimbs/digits/tail phenotype

PCSK5 FAT4 FRAS1 WNT3 LAMB1 LAMC1 RET RNF43 NUBP2 EVX2 DACT1 DST SPRY4 LRP2 LRP4 KMT2A WDSUB1 AGRN DISP1 NOTCH2

3.44e-0512588320MP:0005371
MousePhenoabnormal somatic sensory system morphology

VLDLR FAT4 GRN RET TECTA LDLR GRXCR2 SCUBE1 DST MPP4 KMT2A USH2A MEGF11 DISP1

6.01e-057028314MP:0000959
MousePhenokidney cyst

FAT4 FRAS1 LAMC1 RET SLIT2 DACT1 LRP2

8.56e-05177837MP:0003675
MousePhenoureter hypoplasia

DACT1 LRP4

1.04e-043832MP:0011298
MousePhenoabnormal ureter morphology

LAMC1 RET SLIT2 DACT1 LRP4

1.93e-0490835MP:0000534
MousePhenoabsent visceral yolk sac

WNT3 LAMC1

2.07e-044832MP:0011206
MousePhenoabnormal vas deferens morphology

LAMC1 RET DACT1

2.49e-0421833MP:0002769
MousePhenomuscular atrophy

LAMC1 RET DST AGRN NOTCH3

2.62e-0496835MP:0002269
MousePhenoparesis

LAMC1 DST AGRN NOTCH3

2.71e-0453834MP:0000754
MousePhenoabnormal somatic nervous system morphology

VLDLR FAT4 GRN RET TECTA LDLR GRXCR2 SCUBE1 DST MPP4 LRP4 KMT2A USH2A AGRN MEGF11 DISP1

3.00e-0410258316MP:0002752
MousePhenoabsent anus

PCSK5 DACT1

3.44e-045832MP:0008999
MousePhenokidney microaneurysm

LAMC1 NOTCH2

3.44e-045832MP:0010451
MousePhenoabnormal synapse morphology

GRN RET LDLR DACT1 DST LRP4 AGRN

3.65e-04224837MP:0009538
MousePhenoabnormal metanephric mesenchyme morphology

FRAS1 RET LRP4

4.22e-0425833MP:0010984
MousePhenoabnormal renal glomerular capsule morphology

FRAS1 LAMC1 RET LRRC55 NOTCH2

4.32e-04107835MP:0002828
MousePhenohydronephrosis

LAMC1 RET SLIT2 DACT1 LRP2

4.71e-04109835MP:0000519
MousePhenofailure of neuromuscular synapse presynaptic differentiation

LRP4 AGRN

5.14e-046832MP:0001054
MousePhenoabnormal trabecular bone connectivity density

LRP4 NOTCH2 NOTCH3

5.33e-0427833MP:0010931
MousePhenoabnormal hindlimb morphology

PCSK5 FRAS1 LAMC1 RNF43 NUBP2 DACT1 SPRY4 LRP4 WDSUB1 AGRN NOTCH2

5.77e-045768311MP:0000556
MousePhenoabnormal kidney mesenchyme morphology

FRAS1 RET LRP4

5.94e-0428833MP:0010985
MousePhenoabnormal tail morphology

PCSK5 FAT4 FRAS1 LAMB1 DACT1 DST LRP2 LRP4 KMT2A

6.28e-04403839MP:0002111
DomainEGF

SELE PCSK5 VLDLR FAT4 FRAS1 BRINP3 PAMR1 NOTCH2NLA LAMB1 LAMC1 TECTA ADGRE2 VWCE NOTCH2NLC LDLR SLIT2 SCUBE1 FCGBP OIT3 TNN SLIT1 LRP2 LRP4 ADAM33 HABP2 ADGRE1 LTBP4 AGRN MEGF11 NOTCH2 NOTCH3 PEAR1

2.54e-3623510232SM00181
DomainEGF-like_dom

SELE PCSK5 VLDLR FAT4 FRAS1 PAMR1 NOTCH2NLA LAMB1 LAMC1 TECTA ADGRE2 VWCE NOTCH2NLC LDLR SLIT2 SCUBE1 FCGBP OIT3 TNN SLIT1 LRP2 LRP4 ADAM33 HABP2 ADGRE1 LTBP4 AGRN MEGF11 NOTCH2 NOTCH3 PEAR1

6.65e-3424910231IPR000742
DomainEGF_1

SELE VLDLR FAT4 PAMR1 NOTCH2NLA LAMB1 LAMC1 ADGRE2 VWCE NOTCH2NLC LDLR SLIT2 SCUBE1 OIT3 TNN SLIT1 LRP2 LRP4 ADAM33 HABP2 ADGRE1 USH2A LTBP4 AGRN MEGF11 NOTCH2 NOTCH3 PEAR1

5.32e-2925510228PS00022
DomainEGF_2

SELE VLDLR FAT4 PAMR1 NOTCH2NLA LAMB1 LAMC1 ADGRE2 VWCE NOTCH2NLC LDLR SLIT2 SCUBE1 OIT3 TNN SLIT1 LRP2 LRP4 ADAM33 HABP2 ADGRE1 LTBP4 AGRN MEGF11 NOTCH2 NOTCH3 PEAR1

4.60e-2726510227PS01186
DomainEGF-like_CS

SELE VLDLR FAT4 PAMR1 NOTCH2NLA LAMB1 LAMC1 ADGRE2 VWCE NOTCH2NLC LDLR SLIT2 SCUBE1 TNN SLIT1 LRP2 LRP4 ADAM33 HABP2 ADGRE1 LTBP4 AGRN MEGF11 NOTCH2 NOTCH3 PEAR1

8.42e-2626110226IPR013032
DomainEGF_3

SELE VLDLR FAT4 PAMR1 NOTCH2NLA ADGRE2 VWCE NOTCH2NLC LDLR SLIT2 SCUBE1 OIT3 TNN SLIT1 LRP2 LRP4 ADAM33 HABP2 ADGRE1 LTBP4 AGRN MEGF11 NOTCH2 NOTCH3 PEAR1

1.56e-2523510225PS50026
DomainEGF_CA

VLDLR FAT4 PAMR1 NOTCH2NLA ADGRE2 VWCE NOTCH2NLC LDLR SLIT2 SCUBE1 OIT3 SLIT1 LRP2 LRP4 HABP2 ADGRE1 LTBP4 AGRN NOTCH2 NOTCH3

2.11e-2412210220SM00179
DomainEGF-like_Ca-bd_dom

VLDLR FAT4 PAMR1 NOTCH2NLA ADGRE2 VWCE NOTCH2NLC LDLR SLIT2 SCUBE1 OIT3 SLIT1 LRP2 LRP4 HABP2 ADGRE1 LTBP4 AGRN NOTCH2 NOTCH3

2.97e-2412410220IPR001881
DomainEGF_Ca-bd_CS

VLDLR FAT4 NOTCH2NLA ADGRE2 VWCE NOTCH2NLC LDLR SLIT2 SCUBE1 OIT3 SLIT1 LRP2 LRP4 ADGRE1 LTBP4 NOTCH2 NOTCH3

2.25e-219710217IPR018097
DomainEGF_CA

VLDLR FAT4 NOTCH2NLA ADGRE2 VWCE NOTCH2NLC LDLR SLIT2 SCUBE1 OIT3 SLIT1 LRP2 LRP4 ADGRE1 LTBP4 NOTCH2 NOTCH3

3.25e-219910217PS01187
DomainEGF-type_Asp/Asn_hydroxyl_site

VLDLR FAT4 NOTCH2NLA ADGRE2 VWCE NOTCH2NLC LDLR SLIT2 SCUBE1 OIT3 SLIT1 LRP2 LRP4 ADGRE1 LTBP4 NOTCH2 NOTCH3

1.12e-2010610217IPR000152
DomainGrowth_fac_rcpt_

PCSK5 VLDLR FAT4 FRAS1 BRINP3 LAMB1 LAMC1 ADGRE2 VWCE LDLR SCUBE1 TNN SLIT1 LRP2 LRP4 ADGRE1 LTBP4 NOTCH2 NOTCH3

1.18e-2015610219IPR009030
DomainASX_HYDROXYL

VLDLR FAT4 NOTCH2NLA ADGRE2 VWCE NOTCH2NLC LDLR SLIT2 SCUBE1 OIT3 LRP2 LRP4 ADGRE1 LTBP4 NOTCH2 NOTCH3

1.70e-1910010216PS00010
DomainEGF_CA

VLDLR FAT4 NOTCH2NLA ADGRE2 VWCE NOTCH2NLC LDLR SCUBE1 LRP2 LRP4 ADGRE1 LTBP4 NOTCH2 NOTCH3

2.74e-178610214PF07645
DomainEGF

SELE VLDLR PAMR1 NOTCH2NLA TECTA NOTCH2NLC SLIT2 SLIT1 LRP2 LRP4 HABP2 AGRN NOTCH2 NOTCH3

6.96e-1512610214PF00008
DomainVWC_out

FRAS1 MUC5B TECTA VWCE FCGBP MUC6

5.86e-10191026SM00215
DomainhEGF

FAT4 SLIT2 SLIT1 MEGF11 NOTCH2 NOTCH3

7.81e-09281026PF12661
DomainTIL_dom

MUC5B TECTA FCGBP LRP2 MUC6

8.47e-09141025IPR002919
DomainLaminin_EGF

LAMB1 LAMC1 USH2A AGRN MEGF11 PEAR1

3.26e-08351026PF00053
DomainEGF_Lam

LAMB1 LAMC1 USH2A AGRN MEGF11 PEAR1

3.26e-08351026SM00180
DomainLaminin_EGF

LAMB1 LAMC1 USH2A AGRN MEGF11 PEAR1

5.48e-08381026IPR002049
DomainVWF_dom

FRAS1 MUC5B TECTA VWCE FCGBP MUC6

1.02e-07421026IPR001007
DomainFol_N

SLIT2 FCGBP SLIT1 AGRN

2.69e-07111024IPR003645
DomainFOLN

SLIT2 FCGBP SLIT1 AGRN

2.69e-07111024SM00274
DomainTIL

MUC5B TECTA FCGBP MUC6

4.01e-07121024PF01826
DomainC8

MUC5B TECTA FCGBP MUC6

4.01e-07121024PF08742
DomainUnchr_dom_Cys-rich

MUC5B TECTA FCGBP MUC6

5.77e-07131024IPR014853
DomainC8

MUC5B TECTA FCGBP MUC6

5.77e-07131024SM00832
DomainLaminin_G

FAT4 COL20A1 SLIT2 SLIT1 USH2A AGRN

7.36e-07581026IPR001791
DomainLdl_recept_b

VLDLR LDLR LRP2 LRP4

8.05e-07141024PF00058
DomainLDLRB

VLDLR LDLR LRP2 LRP4

8.05e-07141024PS51120
DomainLY

VLDLR LDLR LRP2 LRP4

1.09e-06151024SM00135
DomainLDLR_classB_rpt

VLDLR LDLR LRP2 LRP4

1.09e-06151024IPR000033
DomainVWD

MUC5B TECTA FCGBP MUC6

1.45e-06161024SM00216
DomainVWF_type-D

MUC5B TECTA FCGBP MUC6

1.45e-06161024IPR001846
DomainVWFD

MUC5B TECTA FCGBP MUC6

1.45e-06161024PS51233
DomainVWD

MUC5B TECTA FCGBP MUC6

1.45e-06161024PF00094
DomainVWC

FRAS1 MUC5B TECTA VWCE FCGBP

1.91e-06381025SM00214
DomainLAM_G_DOMAIN

FAT4 SLIT2 SLIT1 USH2A AGRN

1.91e-06381025PS50025
DomainLDLR_class-A_CS

VLDLR LDLR NETO2 LRP2 LRP4

2.49e-06401025IPR023415
DomainLamG

FAT4 SLIT2 SLIT1 USH2A AGRN

4.04e-06441025SM00282
DomainLdl_recept_a

VLDLR LDLR NETO2 LRP2 LRP4

4.52e-06451025PF00057
Domain-

VLDLR LDLR NETO2 LRP2 LRP4

5.05e-064610254.10.400.10
DomainCT

MUC5B SLIT2 SLIT1 MUC6

5.69e-06221024SM00041
DomainLDLRA_1

VLDLR LDLR NETO2 LRP2 LRP4

6.25e-06481025PS01209
DomainLDLRA_2

VLDLR LDLR NETO2 LRP2 LRP4

6.93e-06491025PS50068
DomainLDrepeatLR_classA_rpt

VLDLR LDLR NETO2 LRP2 LRP4

6.93e-06491025IPR002172
DomainLDLa

VLDLR LDLR NETO2 LRP2 LRP4

6.93e-06491025SM00192
DomainCys_knot_C

MUC5B SLIT2 SLIT1 MUC6

9.71e-06251024IPR006207
DomainCTCK_2

MUC5B SLIT2 SLIT1 MUC6

9.71e-06251024PS01225
DomaincEGF

SCUBE1 LRP2 LRP4 ADGRE1

1.14e-05261024IPR026823
DomaincEGF

SCUBE1 LRP2 LRP4 ADGRE1

1.14e-05261024PF12662
DomainDUF1220

NBPF11 NBPF1 NBPF9

1.30e-0591023SM01148
DomainKAP

KRTAP9-4 KRTAP10-10 KRTAP29-1 KRTAP10-5 KRTAP1-1

1.60e-05581025IPR002494
DomainEGF_extracell

TNN LRP2 ADAM33 MEGF11 NOTCH3

1.89e-05601025IPR013111
DomainEGF_2

TNN LRP2 ADAM33 MEGF11 NOTCH3

1.89e-05601025PF07974
DomainEGF_LAM_2

LAMB1 LAMC1 USH2A AGRN

2.06e-05301024PS50027
DomainEGF_LAM_1

LAMB1 LAMC1 USH2A AGRN

2.06e-05301024PS01248
DomainNBPF_dom

NBPF11 NBPF1 NBPF9

2.53e-05111023IPR010630
DomainNBPF

NBPF11 NBPF1 NBPF9

2.53e-05111023PS51316
DomainDUF1220

NBPF11 NBPF1 NBPF9

2.53e-05111023PF06758
DomainVWFC_2

FRAS1 MUC5B TECTA VWCE

5.37e-05381024PS50184
Domain-

VLDLR LDLR LRP2 LRP4

5.95e-053910242.120.10.30
DomainKeratin_B2

KRTAP9-4 KRTAP10-10 KRTAP10-5 KRTAP1-1

6.59e-05401024PF01500
DomainLaminin_G_2

FAT4 SLIT2 SLIT1 USH2A

6.59e-05401024PF02210
DomainLaminin_N

LAMB1 LAMC1 USH2A

8.41e-05161023IPR008211
DomainLAMININ_NTER

LAMB1 LAMC1 USH2A

8.41e-05161023PS51117
DomainLaminin_N

LAMB1 LAMC1 USH2A

8.41e-05161023PF00055
DomainLamNT

LAMB1 LAMC1 USH2A

8.41e-05161023SM00136
DomainTILa

TECTA FCGBP

8.83e-0531022PF12714
DomainTILa_dom

TECTA FCGBP

8.83e-0531022IPR025615
DomainDUF3454

NOTCH2 NOTCH3

8.83e-0531022PF11936
DomainDUF3454_notch

NOTCH2 NOTCH3

8.83e-0531022IPR024600
DomainDUF3454

NOTCH2 NOTCH3

8.83e-0531022SM01334
DomainTF_fork_head_CS_2

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.15e-04461024IPR030456
Domain6-blade_b-propeller_TolB-like

VLDLR LDLR LRP2 LRP4

1.15e-04461024IPR011042
DomainCTCK_1

MUC5B SLIT2 SLIT1

1.22e-04181023PS01185
DomainTF_fork_head_CS_1

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.25e-04471024IPR018122
DomainFH

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.47e-04491024SM00339
DomainFORK_HEAD_1

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.47e-04491024PS00657
DomainFORK_HEAD_2

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.47e-04491024PS00658
DomainFork_head_dom

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.47e-04491024IPR001766
DomainFORK_HEAD_3

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.47e-04491024PS50039
DomainForkhead

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.47e-04491024PF00250
Domain-

FAT4 SLIT2 SLIT1 USH2A AGRN

1.73e-049510252.60.120.200
DomainNotch

NOTCH2 NOTCH3

1.76e-0441022IPR008297
DomainNODP

NOTCH2 NOTCH3

1.76e-0441022PF07684
DomainNotch_NODP_dom

NOTCH2 NOTCH3

1.76e-0441022IPR011656
DomainNotch_NOD_dom

NOTCH2 NOTCH3

1.76e-0441022IPR010660
DomainNOD

NOTCH2 NOTCH3

1.76e-0441022PF06816
DomainNOD

NOTCH2 NOTCH3

1.76e-0441022SM01338
DomainNODP

NOTCH2 NOTCH3

1.76e-0441022SM01339
DomainLNR

NOTCH2 NOTCH3

2.92e-0451022PS50258
DomainVWC

FRAS1 MUC5B VWCE

4.69e-04281023PF00093
DomainNotch_dom

NOTCH2 NOTCH3

6.09e-0471022IPR000800
DomainNotch

NOTCH2 NOTCH3

6.09e-0471022PF00066
DomainNL

NOTCH2 NOTCH3

6.09e-0471022SM00004
DomainVWFC_1

FRAS1 MUC5B VWCE

9.91e-04361023PS01208
Domain-

FOXD4L6 TFDP2 FOXD4L5 FOXD4L4 FOXD4L3 KDM1B

1.25e-0321810261.10.10.10
DomainKeratin_B2_2

KRTAP9-4 KRTAP10-10 KRTAP29-1

1.25e-03391023PF13885
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL20A1 LAMB1 LAMC1 SCUBE1 DST TNN LRP4 LTBP4 AGRN

7.83e-06300649M610
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

SEMA5A MUC5B MUC6 NOTCH2 NOTCH3

1.38e-0568645M27303
PathwayREACTOME_ECM_PROTEOGLYCANS

LAMB1 LAMC1 TNN LRP4 AGRN

2.37e-0576645M27219
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

VLDLR KRTAP9-4 KRTAP10-10 TRPC5 KRTAP29-1 LAMB1 LAMC1 SEMA5A RET LCE2D TFDP2 KRTAP10-5 SLIT2 SLIT1 KRT40 KRTAP1-1 KMT2A AGRN

4.50e-0514326418M509
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

SEMA5A MUC5B AGRN MUC6 NOTCH2 NOTCH3

4.53e-05143646M27275
PathwayREACTOME_KERATINIZATION

KRTAP9-4 KRTAP10-10 KRTAP29-1 LCE2D KRTAP10-5 KRT40 KRTAP1-1

5.49e-05217647M27640
PathwayREACTOME_KERATINIZATION

KRTAP9-4 KRTAP10-10 KRTAP29-1 KRTAP10-5 KRT40 KRTAP1-1

6.61e-05153646MM15343
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

VLDLR KRTAP9-4 KRTAP10-10 KRTAP29-1 SEMA5A RET KRTAP10-5 SLIT2 KRT40 KRTAP1-1

8.06e-055026410MM14537
PathwayWP_GDNFRET_SIGNALING_AXIS

FAT4 RET SLIT2

1.29e-0422643MM15887
PathwayWP_GDNFRET_SIGNALING_AXIS

FAT4 RET SLIT2

1.48e-0423643M39814
PathwayWP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM

FAT4 FRAS1 RET SLIT2

1.56e-0460644M40048
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE

PCSK5 VLDLR LDLR MYLIP

1.77e-0462644MM14686
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH2 NOTCH3

2.01e-045642M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH2 NOTCH3

3.01e-046642M27068
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE

PCSK5 VLDLR LDLR MYLIP

3.69e-0475644M27032
PathwayREACTOME_PLASMA_LIPOPROTEIN_CLEARANCE

VLDLR LDLR MYLIP

4.83e-0434643MM15566
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMB1 LAMC1 TNN AGRN

5.68e-0484644M7098
PathwayREACTOME_PLASMA_LIPOPROTEIN_CLEARANCE

VLDLR LDLR MYLIP

6.21e-0437643M27847
PathwayREACTOME_REGULATION_OF_COMMISSURAL_AXON_PATHFINDING_BY_SLIT_AND_ROBO

SLIT2 SLIT1

8.92e-0410642M27348
PathwayREACTOME_DISEASES_OF_METABOLISM

SEMA5A MUC5B AGRN MUC6 NOTCH2 NOTCH3

9.30e-04250646M27554
PathwayWP_COMPLEMENT_SYSTEM

SELE LAMB1 LAMC1 LRP2

9.39e-0496644M39581
PathwayWP_GENES_CONTROLLING_NEPHROGENESIS

RET SLIT2 NOTCH2

1.03e-0344643M39891
PathwayREACTOME_NETRIN_1_SIGNALING

TRPC5 SLIT2 SLIT1

1.03e-0344643M875
PathwayPID_INTEGRIN4_PATHWAY

LAMB1 LAMC1

1.09e-0311642M158
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH2 NOTCH3

1.09e-0311642M47865
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

VLDLR TRPC5 LAMB1 LAMC1 SEMA5A RET SLIT2 SLIT1 AGRN

1.09e-03575649M29853
PathwayBIOCARTA_PRION_PATHWAY

LAMB1 LAMC1

1.30e-0312642M22020
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH2 NOTCH3

1.30e-0312642M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH2 NOTCH3

1.30e-0312642M47533
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LDLR LRP2 AGRN

1.33e-0348643M27642
PathwayREACTOME_CYTOSOLIC_IRON_SULFUR_CLUSTER_ASSEMBLY

NUBP2 MMS19

1.53e-0313642M27193
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH2 NOTCH3

1.53e-0313642M47423
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH2 NOTCH3

1.53e-0313642M47534
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_3

VLDLR LDLR

1.53e-0313642M42551
PathwayWP_NEUROGENESIS_REGULATION_IN_THE_OLFACTORY_EPITHELIUM

VLDLR RET AGRN

2.19e-0357643M48326
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC5B MUC6

2.34e-0316642M27410
PathwayREACTOME_VLDLR_INTERNALISATION_AND_DEGRADATION

VLDLR MYLIP

2.34e-0316642M27761
PathwayREACTOME_VLDLR_INTERNALISATION_AND_DEGRADATION

VLDLR MYLIP

2.34e-0316642MM15506
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMB1 LAMC1 AGRN

2.42e-0359643M27218
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC5B MUC6

2.64e-0317642M27412
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH2 NOTCH3

2.96e-0318642M614
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF8 NBPF12 NBPF11 NBPF1 NBPF9 NBPF10

4.07e-1121108616079250
Pubmed

Evolution of Human Brain Size-Associated NOTCH2NL Genes Proceeds toward Reduced Protein Levels.

NOTCH2NLA NOTCH2NLC NOTCH2NLB NOTCH2

8.79e-114108432330268
Pubmed

A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 SPRY4

3.32e-1013108516884697
Pubmed

Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis.

NOTCH2NLA NOTCH2NLC NOTCH2NLB NOTCH2

4.39e-105108429856954
Pubmed

Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.

VLDLR FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

7.70e-1015108522045912
Pubmed

Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.31e-096108427092474
Pubmed

The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

6.10e-09810848530406
Pubmed

An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.09e-089108412412011
Pubmed

Evolutionary history and genome organization of DUF1220 protein domains.

NBPF8 NBPF12 NBPF1 NBPF9

1.82e-0810108422973535
Pubmed

Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

6.15e-081310847957066
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

NBPF8 NBPF12 MUC5B NBPF11 NBPF1 SLIT2 NBPF9 NBPF10

6.42e-08170108823314748
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

PCSK5 PAMR1 LAMB1 LAMC1 GRN LDLR SLIT2 LTBP4 AGRN

8.73e-08248108924006456
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

PCSK5 WBP1 LAMB1 GRN ADAM33 LTBP4 AGRN

9.08e-08118108721078624
Pubmed

Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex.

NOTCH2NLA NOTCH2NLC NOTCH2NLB

1.16e-074108329561261
Pubmed

FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors.

VLDLR LDLR MYLIP

1.16e-074108322109552
Pubmed

Six members of the mouse forkhead gene family are developmentally regulated.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.17e-071510847689224
Pubmed

Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.55e-071610848861101
Pubmed

Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.55e-0716108410208738
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

NOTCH2NLA LAMC1 GRN VWCE SLIT2 SLIT1 FHL3 LTBP4 AGRN MEGF11 NOTCH2 NOTCH3

1.85e-075601081221653829
Pubmed

FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines.

FOXD4L6 FOXD4L5 FOXD4L4

2.90e-075108312234674
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

VLDLR LDLR LRP2

2.90e-075108318685438
Pubmed

Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation.

NOTCH2NLA NOTCH2NLC NOTCH2NLB

2.90e-075108329856955
Pubmed

Distinct functional domains contribute to degradation of the low density lipoprotein receptor (LDLR) by the E3 ubiquitin ligase inducible Degrader of the LDLR (IDOL).

VLDLR LDLR MYLIP

2.90e-075108321734303
Pubmed

Functional equivalency between Otx2 and Otx1 in development of the rostral head.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

3.29e-071910849895322
Pubmed

Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

4.10e-0720108412812790
Pubmed

Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

5.05e-072110849449667
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

VLDLR LDLR LRP2 LRP4

5.05e-0721108421337463
Pubmed

PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain.

PCSK5 VLDLR LDLR

5.78e-076108320453200
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

NBPF8 FAT4 FRAS1 NBPF12 NBPF11 TECTA NBPF1 DST STARD9 NBPF9 NBPF10

6.15e-075131081125798074
Pubmed

Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

6.16e-0722108417389379
Pubmed

Renal collecting system growth and function depend upon embryonic γ1 laminin expression.

LAMB1 LAMC1 RET AGRN

7.44e-0723108421903675
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

VLDLR RET LDLR LRP2 NOTCH2 NOTCH3

7.77e-07101108623382219
Pubmed

Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

8.91e-0724108411820816
Pubmed

A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

8.91e-0724108429992973
Pubmed

Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor.

ADGRE1 MEGF11 PEAR1

1.01e-067108319915564
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

VLDLR LDLR LRP2

1.01e-067108312169628
Pubmed

ERp57 is essential for efficient folding of glycoproteins sharing common structural domains.

LAMB1 LAMC1 LDLR AGRN

1.06e-0625108417170699
Pubmed

Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.25e-0626108415857913
Pubmed

Increased expression of laminin-1 and collagen (IV) subunits in the aganglionic bowel of ls/ls, but not c-ret -/- mice.

LAMB1 LAMC1 RET

1.61e-06810838812145
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

FRAS1 COL20A1 LAMB1 LAMC1 AGRN

1.73e-0664108522261194
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

VLDLR CERK LAMB1 LDLR RNF43 TFDP2 SLIT2 TRIM66 LRP2 LRP4 MMS19 KDM1B FHL3 LTBP4 NOTCH2

1.93e-0611161081531753913
Pubmed

Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

1.97e-0629108422972626
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

FRAS1 LAMB1 LAMC1 AGRN

1.97e-0629108422613833
Pubmed

Functional analysis of secreted and transmembrane proteins critical to mouse development.

LAMB1 LAMC1 AGRN NOTCH3

2.59e-0631108411431694
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

PCSK5 FAT4 NOTCH2NLA LAMB1 GRN SLIT1 LRP2 ADAM33 LTBP4 AGRN MEGF11

3.18e-066081081116713569
Pubmed

Basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome.

FRAS1 LAMC1 AGRN

3.44e-0610108315623520
Pubmed

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.

LAMB1 LAMC1 AGRN

8.14e-0613108312682087
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PCSK5 FRAS1 LDLR RNF43 CLDN23 CASZ1 NBPF1 DACT1 DST LRP4 ESPL1 LTBP4 AGRN NOTCH2

8.56e-0611051081435748872
Pubmed

cDNA cloning, expression and mapping of human laminin B2 gene to chromosome 1q31.

LAMB1 LAMC1

9.55e-06210823402995
Pubmed

Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake.

LDLR MYLIP

9.55e-062108226719329
Pubmed

A neuronal VLDLR variant lacking the third complement-type repeat exhibits high capacity binding of apoE containing lipoproteins.

VLDLR LDLR

9.55e-062108219393635
Pubmed

IDOL, inducible degrader of low-density lipoprotein receptor, serves as a potential therapeutic target for dyslipidemia.

LDLR MYLIP

9.55e-062108226601593
Pubmed

NOTCH Single Nucleotide Polymorphisms in the Predisposition of Breast and Colorectal Cancers in Saudi Patients.

NOTCH2 NOTCH3

9.55e-062108234257585
Pubmed

A novel disulfide pattern in laminin-type epidermal growth factor-like (LE) modules of laminin β1 and γ1 chains.

LAMB1 LAMC1

9.55e-062108220731416
Pubmed

The N342S MYLIP polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans.

LDLR MYLIP

9.55e-062108221765216
Pubmed

Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses.

LRP4 AGRN

9.55e-062108222854782
Pubmed

The Tat protein of the caprine arthritis encephalitis virus interacts with the Notch2 EGF-like repeats and the epithelin/granulin precursor.

GRN NOTCH2

9.55e-062108212931033
Pubmed

Effects of Notch2 and Notch3 on Cell Proliferation and Apoptosis of Trophoblast Cell Lines.

NOTCH2 NOTCH3

9.55e-062108226640406
Pubmed

Znf202 affects high density lipoprotein cholesterol levels and promotes hepatosteatosis in hyperlipidemic mice.

ZNF202 LDLR

9.55e-062108223469003
Pubmed

Agrin binds to the nerve-muscle basal lamina via laminin.

LAMB1 AGRN

9.55e-06210829151673
Pubmed

Notch2 and Notch3 function together to regulate vascular smooth muscle development.

NOTCH2 NOTCH3

9.55e-062108222615991
Pubmed

Genetic spectrum and clinical features of adult leukoencephalopathies in a Chinese cohort.

NOTCH2NLC NOTCH3

9.55e-062108237237429
Pubmed

Constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12.1) in a neuroblastoma patient. Establishment of somatic cell hybrids and identification of PND/A12M2 on chromosome 1 and NF1/SCYA7 on chromosome 17 as breakpoint flanking single copy markers.

NBPF11 NBPF1

9.55e-06210827700633
Pubmed

Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97.

ADGRE2 ADGRE1

9.55e-062108210903844
Pubmed

Computational modeling of laminin N-terminal domains using sparse distance constraints from disulfide bonds and chemical cross-linking.

LAMB1 LAMC1

9.55e-062108220939100
Pubmed

Permissive corridor and diffusible gradients direct medial ganglionic eminence cell migration to the neocortex.

SLIT2 SLIT1

9.55e-062108212515855
Pubmed

Expression of notch family proteins in placentas from patients with early-onset severe preeclampsia.

NOTCH2 NOTCH3

9.55e-062108224336671
Pubmed

Slit proteins: molecular guidance cues for cells ranging from neurons to leukocytes.

SLIT2 SLIT1

9.55e-062108212200164
Pubmed

IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor.

LDLR MYLIP

9.55e-062108223382078
Pubmed

Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor.

VLDLR LDLR

9.55e-062108210024503
Pubmed

Directional guidance of neuronal migration in the olfactory system by the protein Slit.

SLIT2 SLIT1

9.55e-062108210432110
Pubmed

LDL receptor deficiency unmasks altered VLDL triglyceride metabolism in VLDL receptor transgenic and knockout mice.

VLDLR LDLR

9.55e-062108211108739
Pubmed

Transgenic expression of dominant-active IDOL in liver causes diet-induced hypercholesterolemia and atherosclerosis in mice.

LDLR MYLIP

9.55e-062108224935961
Pubmed

Steerable-filter based quantification of axonal populations at the developing optic chiasm reveal significant defects in Slit2(-/-) as well as Slit1(-/-)Slit2(-/-) embryos.

SLIT2 SLIT1

9.55e-062108223320558
Pubmed

Slit1 and slit2 proteins control the development of the lateral olfactory tract.

SLIT2 SLIT1

9.55e-062108212097499
Pubmed

Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptor.

VLDLR LDLR

9.55e-06210828636110
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

VLDLR LDLR LRP2

1.03e-0514108317389516
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

FRAS1 LAMB1 GRN MUC5B LDLR AGRN

1.29e-05164108632409323
Pubmed

TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.

SEMA5A RET SLIT2 SLIT1

1.42e-0547108435462405
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

WNT3 LAMB1 CASZ1 SLIT2 SLIT1 NBPF10 NOTCH2 NOTCH3

1.68e-05358108832460013
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

FRAS1 LAMB1 LAMC1

2.30e-0518108314730302
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

VLDLR LDLR LRP2

2.30e-0518108310827173
Pubmed

ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.

LAMB1 LAMC1 ADGRE1

2.30e-0518108339040056
Pubmed

Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney.

LAMC1 RET SLIT2

2.72e-0519108316319112
Pubmed

Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves.

SLIT2 SLIT1 NOTCH2

2.72e-0519108325691540
Pubmed

Transcriptional fates of human-specific segmental duplications in brain.

NOTCH2NLA NOTCH2NLC NOTCH2NLB

2.72e-0519108330228200
Pubmed

Developmental loss of laminin from the interstitial extracellular matrix correlates with decreased laminin gene expression.

LAMB1 LAMC1

2.86e-05310822100263
Pubmed

The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2.

VLDLR MYLIP

2.86e-053108220427281
Pubmed

Complementary and combinatorial patterns of Notch gene family expression during early mouse development.

NOTCH2 NOTCH3

2.86e-05310828645602
Pubmed

Differential distribution of laminin chains in the development and sex differentiation of mouse internal genitalia.

LAMB1 LAMC1

2.86e-05310827669546
Pubmed

Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system.

SLIT2 SLIT1

2.86e-05310829813312
Pubmed

PCSK9 deficiency unmasks a sex- and tissue-specific subcellular distribution of the LDL and VLDL receptors in mice.

VLDLR LDLR

2.86e-053108226323289
Pubmed

Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis.

NOTCH2 NOTCH3

2.86e-053108227697639
Pubmed

MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters.

LRP4 AGRN

2.86e-053108224244707
Pubmed

Agrin binds to the N-terminal region of Lrp4 protein and stimulates association between Lrp4 and the first immunoglobulin-like domain in muscle-specific kinase (MuSK).

LRP4 AGRN

2.86e-053108221969364
Pubmed

Differential expression of laminin A and B chains during development of embryonic mouse organs.

LAMB1 LAMC1

2.86e-05310822088723
Pubmed

Axonal growth regulation of fetal and embryonic stem cell-derived dopaminergic neurons by Netrin-1 and Slits.

SLIT2 SLIT1

2.86e-053108216840550
Pubmed

The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI.

VLDLR LDLR

2.86e-053108218367731
Pubmed

Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells.

LAMB1 LAMC1

2.86e-05310821292752
Pubmed

Monocytic cells synthesize, adhere to, and migrate on laminin-8 (alpha 4 beta 1 gamma 1).

LAMB1 LAMC1

2.86e-053108211067943
InteractionIGFL3 interactions

PCSK5 VLDLR FRAS1 LAMB1 GRN LDLR LRP2 LRP4 AGRN NOTCH2 NOTCH3

1.20e-137510211int:IGFL3
InteractionHOXA1 interactions

PCSK5 KRTAP9-4 KRTAP10-10 NOTCH2NLA GRN VWCE LCE2D KRTAP10-5 SLIT2 OIT3 SPRY4 SLIT1 KRT40 KRTAP1-1 FHL3 LTBP4 AGRN NOTCH3

2.15e-1335610218int:HOXA1
InteractionZNF408 interactions

VLDLR FRAS1 NOTCH2NLA GRN VWCE LDLR KRT40 KRTAP1-1 LRP2 LRP4 LTBP4 NOTCH2 NOTCH3

4.34e-1314510213int:ZNF408
InteractionZFP41 interactions

FRAS1 GRN LDLR LRP2 LRP4 LTBP4 AGRN NOTCH2 NOTCH3

1.12e-11571029int:ZFP41
InteractionNTN5 interactions

FRAS1 LDLR LRP2 LRP4 LTBP4 NOTCH2 NOTCH3

2.23e-11241027int:NTN5
InteractionLCE3C interactions

PCSK5 KRTAP9-4 KRTAP10-10 NOTCH2NLA GRN LCE2D KRTAP10-5 KRTAP1-1

1.66e-09671028int:LCE3C
InteractionCREB5 interactions

PCSK5 KRTAP9-4 KRTAP10-10 NOTCH2NLA KRTAP10-5 SPRY4 KRT40 KRTAP1-1 FHL3 AGRN

1.08e-0816410210int:CREB5
InteractionWDR25 interactions

FRAS1 NOTCH2NLA LAMB1 LAMC1 KRT40 FHL3 NOTCH3

1.68e-08581027int:WDR25
InteractionNUFIP2 interactions

PCSK5 KRTAP9-4 NOTCH2NLA GRN VWCE RNF43 LCE2D KRTAP10-5 KRTAP1-1 LTBP4 AGRN MEGF11 NOTCH3 PEAR1

2.41e-0841710214int:NUFIP2
InteractionSMCP interactions

PCSK5 KRTAP9-4 NOTCH2NLA GRN LCE2D KRTAP10-5 KRTAP1-1

1.49e-07791027int:SMCP
InteractionADAMTSL4 interactions

PCSK5 KRTAP9-4 NOTCH2NLA LCE2D KRTAP10-5 SLIT1 KRTAP1-1 MYLIP ZFHX2 FHL3

1.53e-0721710210int:ADAMTSL4
InteractionLCE1B interactions

KRTAP9-4 KRTAP10-10 NOTCH2NLA GRN LCE2D KRTAP10-5 KRTAP1-1

2.47e-07851027int:LCE1B
InteractionLCE1F interactions

PCSK5 KRTAP10-10 NOTCH2NLA LCE2D KRTAP10-5 OIT3 KRTAP1-1

4.26e-07921027int:LCE1F
InteractionLCE3E interactions

KRTAP9-4 NOTCH2NLA GRN KRTAP10-5 KRT40 KRTAP1-1

5.81e-07601026int:LCE3E
InteractionIGSF5 interactions

LDLR LRP4 NOTCH2 NOTCH3

5.95e-07141024int:IGSF5
InteractionST14 interactions

LYPD4 PCSK5 VLDLR LAMB1 LDLR SLIT2 NETO2 NOTCH2 NOTCH3

1.07e-062071029int:ST14
InteractionLTBP4 interactions

FOXD4L6 VWCE TRIM66 OIT3 LTBP4 NOTCH2

1.13e-06671026int:LTBP4
InteractionFBXO2 interactions

PCSK5 FRAS1 LAMB1 LAMC1 GRN SLIT2 LRP2 ADAM33 LTBP4 AGRN NOTCH2 NOTCH3

1.14e-0641110212int:FBXO2
InteractionOTX1 interactions

PCSK5 KRTAP9-4 NOTCH2NLA GRN LCE2D KRTAP10-5 SPRY4 KRTAP1-1

1.22e-061551028int:OTX1
InteractionLCE1E interactions

KRTAP10-10 NOTCH2NLA GRN LCE2D KRTAP10-5 KRTAP1-1

1.23e-06681026int:LCE1E
InteractionZNF696 interactions

VWCE KRTAP10-5 OIT3 KRT40 KRTAP1-1 NOTCH2

1.23e-06681026int:ZNF696
InteractionLCE1D interactions

PCSK5 NOTCH2NLA GRN LCE2D KRTAP10-5 KRTAP1-1

1.46e-06701026int:LCE1D
InteractionKRTAP1-1 interactions

PCSK5 CERK GRN LCE2D NUBP2 KRTAP10-5 FOXD4L3 SLIT1 KRTAP1-1

1.71e-062191029int:KRTAP1-1
InteractionCYSRT1 interactions

PCSK5 CERK KRTAP10-10 NOTCH2NLA GRN LCE2D NUBP2 KRTAP10-5 FOXD4L3 SLIT1 KRTAP1-1 ZFHX2 FHL3

1.84e-0651110213int:CYSRT1
InteractionLCE3A interactions

PCSK5 NOTCH2NLA LCE2D KRTAP10-5 OIT3 KRTAP1-1

2.38e-06761026int:LCE3A
InteractionZNF707 interactions

FRAS1 KRTAP10-5 LRP4 LTBP4 NOTCH2 NOTCH3

2.99e-06791026int:ZNF707
InteractionLCE4A interactions

KRTAP9-4 NOTCH2NLA GRN LCE2D KRTAP10-5 KRTAP1-1

3.22e-06801026int:LCE4A
InteractionGARIN6 interactions

NOTCH2NLA KRT40 KRTAP1-1 FHL3

3.46e-06211024int:GARIN6
InteractionCFC1 interactions

PCSK5 FRAS1 LAMB1 LAMC1 LTBP4 AGRN NOTCH2

3.56e-061261027int:CFC1
InteractionZSCAN21 interactions

FRAS1 GRN VWCE KRTAP10-5 KRT40 LRP4 NOTCH2

3.96e-061281027int:ZSCAN21
InteractionPRG3 interactions

PCSK5 FRAS1 LDLR SLIT2 NOTCH2

4.81e-06491025int:PRG3
InteractionATN1 interactions

PCSK5 GRN SLIT1 LRP2 KMT2A LTBP4 AGRN MEGF11

4.93e-061871028int:ATN1
InteractionLCE2C interactions

PCSK5 KRTAP10-10 NOTCH2NLA LCE2D KRTAP10-5 KRTAP1-1

5.61e-06881026int:LCE2C
InteractionKRTAP5-6 interactions

KRTAP9-4 KRTAP10-10 NOTCH2NLA LCE2D KRTAP10-5 KRTAP1-1

8.23e-06941026int:KRTAP5-6
InteractionSLC23A1 interactions

NOTCH2NLA KRTAP10-5 KRT40 KRTAP1-1

8.49e-06261024int:SLC23A1
InteractionMXI1 interactions

NOTCH2NLA KRTAP10-5 KRT40 KRTAP1-1 PEAR1

8.56e-06551025int:MXI1
InteractionKRTAP5-9 interactions

PCSK5 KRTAP9-4 KRTAP10-10 NOTCH2NLA GRN LCE2D KRTAP10-5 KRTAP1-1

9.01e-062031028int:KRTAP5-9
InteractionSHFL interactions

PCSK5 NOTCH2NLA KLF15 KRTAP10-5 KRT40 KRTAP1-1

9.87e-06971026int:SHFL
InteractionZNF439 interactions

NOTCH2NLA KRTAP10-5 KRT40 KRTAP1-1

9.92e-06271024int:ZNF439
InteractionTRIM42 interactions

PCSK5 CERK NOTCH2NLA LCE2D KRTAP10-5 SLIT1 KRT40

1.08e-051491027int:TRIM42
InteractionFEZF1 interactions

KRT40 KRTAP1-1 LRP2 LRP4

1.15e-05281024int:FEZF1
InteractionCTSZ interactions

PLK2 KRTAP10-10 NOTCH2NLA KRT40 KRTAP1-1

1.21e-05591025int:CTSZ
InteractionKRTAP12-1 interactions

NOTCH2NLA GRN KRTAP10-5 KRTAP1-1 FHL3

1.68e-05631025int:KRTAP12-1
InteractionFBN2 interactions

LYPD4 FOXD4L6 VWCE TRIM66 NOTCH2

1.95e-05651025int:FBN2
InteractionPOM121L8P interactions

NOTCH2NLA KRTAP10-5 KRT40

2.02e-05111023int:POM121L8P
InteractionDOCK2 interactions

PCSK5 KRTAP9-4 NOTCH2NLA KRT40 KRTAP1-1

2.10e-05661025int:DOCK2
InteractionSPRY1 interactions

PCSK5 NOTCH2NLA LCE2D KRTAP10-5 SPRY4 KRTAP1-1

2.14e-051111026int:SPRY1
InteractionNR1D2 interactions

PCSK5 NOTCH2NLA KRT40 KRTAP1-1 MYLIP

2.27e-05671025int:NR1D2
InteractionZNF74 interactions

VWCE LRP4 LTBP4 NOTCH3

2.55e-05341024int:ZNF74
InteractionSLC6A20 interactions

NOTCH2NLA KRTAP10-5 KRTAP1-1 LRRC15

2.55e-05341024int:SLC6A20
InteractionZNF417 interactions

NOTCH2NLA KRTAP10-5 KRT40 KRTAP1-1 MYLIP FHL3 NOTCH2

3.40e-051781027int:ZNF417
InteractionLCE3D interactions

PCSK5 NOTCH2NLA LCE2D KRTAP10-5 KRTAP1-1

3.44e-05731025int:LCE3D
InteractionWT1-AS interactions

NOTCH2NLA KRTAP10-5 KRT40

3.47e-05131023int:WT1-AS
InteractionLCE2D interactions

NOTCH2NLA GRN LCE2D KRTAP10-5 KRTAP1-1

3.67e-05741025int:LCE2D
InteractionCACNA1A interactions

PCSK5 WBP1 LAMB1 GRN LTBP4 AGRN

3.82e-051231026int:CACNA1A
InteractionITGB4 interactions

NOTCH2NLA LAMB1 LAMC1 DST KRT40 KRTAP1-1

4.18e-051251026int:ITGB4
InteractionKRTAP4-5 interactions

NOTCH2NLA LCE2D KRTAP10-5 KRTAP1-1 PEAR1

4.18e-05761025int:KRTAP4-5
InteractionVLDLR interactions

VLDLR LDLR TRIM66 MYLIP

4.44e-05391024int:VLDLR
InteractionEGFL7 interactions

GRN VWCE ADAM33 NOTCH2 NOTCH3

4.45e-05771025int:EGFL7
InteractionGLRX3 interactions

PCSK5 NOTCH2NLA GRN LCE2D KRTAP10-5 DST MMS19

5.32e-051911027int:GLRX3
InteractionADAMTSL3 interactions

NOTCH2NLA KRT40 KRTAP1-1

5.48e-05151023int:ADAMTSL3
InteractionKRTAP4-4 interactions

KRTAP10-10 NOTCH2NLA LCE2D KRTAP10-5 KRTAP1-1

5.68e-05811025int:KRTAP4-4
InteractionLCE2B interactions

NOTCH2NLA GRN LCE2D KRTAP10-5 KRTAP1-1

5.68e-05811025int:LCE2B
InteractionPOU4F2 interactions

PCSK5 GRN KRTAP10-5 SPRY4 KRTAP1-1

6.39e-05831025int:POU4F2
InteractionZNF587 interactions

KRTAP10-10 NOTCH2NLA KRTAP10-5 KRT40 KRTAP1-1 FHL3

6.43e-051351026int:ZNF587
InteractionSCNM1 interactions

NOTCH2NLA KLF15 ZNF202 KRTAP10-5 KRT40 KRTAP1-1 MYLIP

6.47e-051971027int:SCNM1
InteractionZNF32 interactions

NOTCH2NLA KRTAP10-5 NOTCH2

6.72e-05161023int:ZNF32
InteractionLCE1A interactions

NOTCH2NLA GRN LCE2D KRTAP10-5 KRTAP1-1

6.77e-05841025int:LCE1A
InteractionDMRT3 interactions

NOTCH2NLA GRN KRT40 KRTAP1-1 FHL3

8.00e-05871025int:DMRT3
InteractionGUCD1 interactions

PCSK5 LCE2D KRT40 KRTAP1-1 FHL3

8.45e-05881025int:GUCD1
InteractionSLURP1 interactions

PCSK5 LAMB1 LAMC1 GRN LDLR NOTCH2

9.19e-051441026int:SLURP1
InteractionLCE5A interactions

NOTCH2NLA GRN LCE2D KRTAP10-5 KRTAP1-1

9.40e-05901025int:LCE5A
InteractionTIMP3 interactions

FRAS1 VWCE LDLR LRP2 NOTCH2

9.40e-05901025int:TIMP3
InteractionCERK interactions

CERK NOTCH2NLA VWCE TRIM66 KRTAP1-1

9.91e-05911025int:CERK
InteractionWNT3A interactions

WNT3 LAMC1 LDLR NOTCH2

1.10e-04491024int:WNT3A
InteractionFOXD4L6 interactions

FOXD4L6 LDLR LTBP4 NOTCH2

1.10e-04491024int:FOXD4L6
InteractionKRTAP9-2 interactions

CERK KRTAP9-4 NOTCH2NLA LCE2D KRTAP10-5 KRTAP1-1

1.11e-041491026int:KRTAP9-2
InteractionTRPV6 interactions

NOTCH2NLA KRTAP10-5 KRT40

1.15e-04191023int:TRPV6
InteractionCCN6 interactions

FRAS1 LDLR NOTCH2

1.15e-04191023int:CCN6
InteractionTAPBPL interactions

NOTCH2NLA KRT40 KRTAP1-1

1.15e-04191023int:TAPBPL
InteractionZNF224 interactions

LRP2 LRP4 NOTCH3

1.35e-04201023int:ZNF224
InteractionCSF1 interactions

NOTCH2NLA KRTAP1-1 FHL3

1.35e-04201023int:CSF1
InteractionNOTCH2NLA interactions

PCSK5 CERK KRTAP9-4 KRTAP10-10 NOTCH2NLA RET LCE2D NUBP2 KRTAP10-5

1.37e-043811029int:NOTCH2NLA
InteractionMFAP5 interactions

GRN LDLR LTBP4 NOTCH3

1.39e-04521024int:MFAP5
InteractionZNF669 interactions

VWCE KRTAP1-1 LRP4 LTBP4

1.39e-04521024int:ZNF669
InteractionKRTAP13-2 interactions

NOTCH2NLA GRN KRTAP10-5 SLIT1 KRTAP1-1

1.48e-04991025int:KRTAP13-2
InteractionKRTAP9-8 interactions

NOTCH2NLA LCE2D NUBP2 KRTAP10-5 KRTAP1-1

1.55e-041001025int:KRTAP9-8
InteractionDEFA1 interactions

LAMB1 GRN LDLR SLIT2 NOTCH3

1.55e-041001025int:DEFA1
InteractionNEK4 interactions

NBPF8 FAT4 FRAS1 NBPF12 NBPF11 TECTA NBPF1 DST STARD9 NBPF9 NBPF10

1.75e-0458210211int:NEK4
InteractionDCDC2B interactions

FAT4 KRT40 FHL3

1.81e-04221023int:DCDC2B
InteractionGNE interactions

NOTCH2NLA GRN KRTAP10-5 KRT40 KRTAP1-1

1.86e-041041025int:GNE
InteractionPRKAB2 interactions

KRTAP9-4 KLF15 GRN KRTAP10-5 DST KRT40 KRTAP1-1

1.88e-042341027int:PRKAB2
InteractionKRTAP10-8 interactions

PCSK5 KRTAP9-4 KRTAP10-10 NOTCH2NLA GRN LCE2D KRTAP10-5 SLIT1 KRTAP1-1

2.00e-044011029int:KRTAP10-8
InteractionLYPD1 interactions

PCSK5 FRAS1 LAMB1 NOTCH2

2.13e-04581024int:LYPD1
InteractionC11orf87 interactions

NOTCH2NLA KRTAP10-5 KRT40 KRTAP1-1

2.13e-04581024int:C11orf87
InteractionKRTAP11-1 interactions

PCSK5 CERK GRN KRTAP10-5 OIT3

2.22e-041081025int:KRTAP11-1
InteractionZNF124 interactions

NOTCH2NLA KRTAP10-5 KRT40 KRTAP1-1

2.27e-04591024int:ZNF124
InteractionATXN7 interactions

LAMB1 GRN ADAM33 LTBP4 AGRN

2.32e-041091025int:ATXN7
InteractionFBXL18 interactions

LYPD4 NOTCH2NLA KRT40 FHL3

2.43e-04601024int:FBXL18
InteractionMANEA interactions

LAMB1 LAMC1 RET AGRN

2.43e-04601024int:MANEA
Cytoband9q21.11

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

7.57e-073010849q21.11
CytobandEnsembl 112 genes in cytogenetic band chr1q21

NBPF12 NOTCH2NLA NBPF11 NOTCH2NLC LCE2D NOTCH2NLB NBPF9 NBPF10

5.49e-064041088chr1q21
Cytoband1q21.1

NBPF8 NBPF11 NBPF9 NBPF10

1.45e-056210841q21.1
CytobandEnsembl 112 genes in cytogenetic band chr17q21

KRTAP9-4 WNT3 KRTAP29-1 GRN KRTAP4-16 KRT40 KRTAP1-1

1.34e-044731087chr17q21
CytobandEnsembl 112 genes in cytogenetic band chr9q21

PCSK5 FOXD4L5 FOXD4L4 FOXD4L3

1.29e-031991084chr9q21
Cytoband17q12-q21

KRTAP9-4 KRTAP4-16

2.60e-0332108217q12-q21
GeneFamilyNeuroblastoma breakpoint family

NBPF8 NBPF12 NBPF11 NBPF1 NBPF9 NBPF10

2.59e-1023706662
GeneFamilyLow density lipoprotein receptors

VLDLR LDLR LRP2 LRP4

1.43e-0713704634
GeneFamilyKeratin associated proteins

KRTAP9-4 KRTAP10-10 KRTAP29-1 KRTAP4-16 KRTAP10-5 KRTAP1-1

4.01e-06109706619
GeneFamilyCD molecules|Adhesion G protein-coupled receptors, subfamily E

ADGRE2 ADGRE1

1.47e-045702915
GeneFamilyCytosolic iron-sulfur assembly components

NUBP2 MMS19

2.19e-0467021028
GeneFamilyLaminin subunits

LAMB1 LAMC1

9.51e-0412702626
GeneFamilyCadherin related

FAT4 RET

1.94e-031770224
GeneFamilyCD molecules|Mucins

MUC5B MUC6

2.96e-0321702648
CoexpressionNABA_MATRISOME

PCSK5 FRAS1 BRINP3 PAMR1 COL20A1 WNT3 LAMB1 LAMC1 SEMA5A MUC5B TECTA VWCE IFNA2 SLIT2 SCUBE1 OIT3 TNN SLIT1 ADAM33 HABP2 USH2A LTBP4 AGRN MUC6 MEGF11

1.18e-13102610225M5889
CoexpressionNABA_MATRISOME

PCSK5 FRAS1 BRINP3 PAMR1 COL20A1 WNT3 LAMB1 LAMC1 SEMA5A MUC5B TECTA VWCE IFNA2 SLIT2 SCUBE1 OIT3 TNN SLIT1 ADAM33 HABP2 LTBP4 AGRN MUC6 MEGF11

6.56e-13100810224MM17056
CoexpressionNABA_ECM_GLYCOPROTEINS

FRAS1 LAMB1 LAMC1 TECTA VWCE SLIT2 OIT3 TNN SLIT1 USH2A LTBP4 AGRN

1.64e-1119610212M3008
CoexpressionNABA_CORE_MATRISOME

FRAS1 COL20A1 LAMB1 LAMC1 TECTA VWCE SLIT2 OIT3 TNN SLIT1 USH2A LTBP4 AGRN

5.73e-1127510213M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

FRAS1 LAMB1 LAMC1 TECTA VWCE SLIT2 OIT3 TNN SLIT1 LTBP4 AGRN

2.31e-1019110211MM17059
CoexpressionNABA_CORE_MATRISOME

FRAS1 COL20A1 LAMB1 LAMC1 TECTA VWCE SLIT2 OIT3 TNN SLIT1 LTBP4 AGRN

6.64e-1027010212MM17057
CoexpressionHU_FETAL_RETINA_FIBROBLAST

PLK2 MDFIC LAMB1 LAMC1 SCUBE1 MYLIP FHL3 LTBP4 NOTCH2 NOTCH3 PEAR1

3.21e-0738510211M39264
CoexpressionFAN_EMBRYONIC_CTX_OPC

BRINP3 COL20A1 SEMA5A SPRY4 TSPAN13

2.41e-06551025M39038
CoexpressionPEREZ_TP53_AND_TP63_TARGETS

PCSK5 RET CASZ1 LY6D SLIT2 MYLIP NOTCH3

1.70e-052071027M14566
CoexpressionNABA_BASEMENT_MEMBRANES

LAMB1 LAMC1 USH2A AGRN

1.77e-05401024M5887
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3

FOXD4L6 RET CLDN23 CASZ1 FOXD4L5 FOXD4L4 FOXD4L3

2.30e-052171027MM861
CoexpressionNABA_MATRISOME_ASSOCIATED

PCSK5 BRINP3 PAMR1 WNT3 SEMA5A MUC5B IFNA2 SCUBE1 ADAM33 HABP2 MUC6 MEGF11

3.03e-0573810212MM17058
CoexpressionNABA_MATRISOME_ASSOCIATED

PCSK5 BRINP3 PAMR1 WNT3 SEMA5A MUC5B IFNA2 SCUBE1 ADAM33 HABP2 MUC6 MEGF11

3.59e-0575110212M5885
CoexpressionBENPORATH_SUZ12_TARGETS

BRINP3 FAM163A WNT3 TRPC5 NOTCH2NLA NBPF11 CASZ1 SLIT2 FOXD4L4 FOXD4L3 SLIT1 LRP2 MEGF11 NOTCH2

4.80e-05103510214M9898
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HPERIC

PAMR1 LAMB1 LAMC1 SEMA5A GRN LRRC55 DACT1 TNN SPRY4 AGRN NOTCH2 NOTCH3

6.20e-0579510212M39050
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

FAT4 MDFIC FAM163A LAMB1 RET CLDN23 CASZ1 OVOL2 SCUBE1 SPRY4 LRP2 FHL3 MEGF11 PEAR1

7.14e-05107410214M1941
CoexpressionMEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3

FOXD4L6 RET CASZ1 FOXD4L5 OVOL2 FOXD4L4 SCUBE1 FOXD4L3

7.89e-053571028MM828
CoexpressionTRAVAGLINI_LUNG_PERICYTE_CELL

LAMB1 SEMA5A SPRY4 NOTCH3 PEAR1

8.48e-051141025M41678
CoexpressionLIM_MAMMARY_STEM_CELL_UP

PAMR1 LAMB1 LAMC1 SEMA5A SLIT2 DST NETO2 LRP4 LTBP4

1.07e-044791029M2573
CoexpressionLIM_MAMMARY_STEM_CELL_UP

PAMR1 LAMB1 LAMC1 SEMA5A SLIT2 DST NETO2 LRP4 LTBP4

1.14e-044831029MM1082
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_PERICYTE

SEMA5A STARD9 SPRY4 AGRN NOTCH3 PEAR1

1.17e-041951026M45684
CoexpressionAIZARANI_LIVER_C33_STELLATE_CELLS_2

LAMB1 LAMC1 SEMA5A DST NOTCH3

1.36e-041261025M39132
CoexpressionRIGGINS_TAMOXIFEN_RESISTANCE_UP

RET SPRY4 LRP4 LRRC15

1.37e-04671024M17487
CoexpressionNEWMAN_ERCC6_TARGETS_UP

PCSK5 CLDN23 MYLIP

1.39e-04261023M5459
CoexpressionBENPORATH_PRC2_TARGETS

BRINP3 FAM163A TRPC5 NBPF11 CASZ1 SLIT2 FOXD4L4 FOXD4L3 SLIT1 LRP2

2.26e-0465010210M8448
CoexpressionTHEODOROU_MAMMARY_TUMORIGENESIS

WNT3 KLF15 LAMB1

2.38e-04311023M1291
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500

VLDLR FRAS1 PAMR1 LAMB1 LAMC1 SEMA5A SLIT2 LRP2 LRP4 HABP2 AGRN NOTCH2

1.91e-073989412gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_500

FRAS1 PAMR1 LAMB1 LAMC1 SLIT2 LRP4 AGRN

8.74e-06165947gudmap_kidney_P4_CapMesRenVes_Crym_k3_500
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000

VLDLR FRAS1 PAMR1 LAMB1 LAMC1 SEMA5A SLIT2 TSPAN13 LRP2 LRP4 HABP2 AGRN NOTCH2

4.04e-057839413gudmap_kidney_P4_CapMesRenVes_Crym_1000
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 BRINP3 PAMR1 LAMB1 SCUBE1 DST LRP4 ADAM33 LTBP4

6.28e-101811089b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYPD4 CERK WNT3 LDLR LY6D LRP4 NOTCH2 NOTCH3

1.03e-0817310880f9c1d3298e59e6d22bb3306f0f445f490be8bbd
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Krt80|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCSK5 TRPC5 CLDN23 CASZ1 SLIT2 MYLIP DISP1

5.47e-08141108740ef6d792e11fe10963d64eb0b606b90556c1a70
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 FAT4 PLK2 LRRC55 DST NETO2 LTBP4

3.01e-0718110874d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VLDLR PAMR1 KLF15 LAMB1 SLIT2 LRP4 LTBP4

4.32e-0719110878a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCSK5 FAT4 LAMC1 SLIT2 DST ADAM33 LTBP4

4.97e-071951087f54bc4454270ff06e85596f98199372b50d0179f
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLK2 LAMB1 LAMC1 SEMA5A SLIT2 LRP4 LTBP4

5.32e-071971087eb07545bef5ad506fbbe3a1f99131f26c1447a31
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FAT4 PAMR1 LAMB1 LAMC1 STARD9 AGRN NOTCH3

5.32e-0719710872872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCellfacs-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 VLDLR PAMR1 LAMB1 LAMC1 DACT1 LTBP4

5.51e-0719810870dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLK2 LAMB1 LAMC1 SEMA5A SLIT2 LRP4 LTBP4

5.70e-07199108730ab0750d51f168b18c434c974d24a4e70f29cc7
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PCSK5 FAT4 PAMR1 LAMB1 DST LRP4 LTBP4

5.70e-07199108738cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCSK5 CLDN23 CASZ1 SLIT2 MYLIP DISP1

1.20e-0614010867cc891d676555609add6fc7880735d948a2ad801
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-6|TCGA-Skin / Sample_Type by Project: Shred V9

KRTAP9-4 KRTAP10-10 KRTAP29-1 KRTAP10-5 KRT40 KRTAP1-1

1.53e-061461086522c32103c24fc26836bb5b642083904682d9292
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VLDLR BRINP3 NOTCH2NLA NOTCH2NLB NBPF10 NOTCH2

2.17e-0615510865fabe24a784f0be46040ffc886eabd8d5ce78121
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLK2 MUC5B LDLR LRRC55 FCGBP NETO2

3.34e-0616710868fede587572d465cb63f7828141a574185bbb819
ToppCell356C-Fibroblasts-Fibroblast-H-|356C / Donor, Lineage, Cell class and subclass (all cells)

PAMR1 RET SLIT2 DACT1 MPP4 NOTCH3

3.46e-061681086b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell356C-Fibroblasts-Fibroblast-H|356C / Donor, Lineage, Cell class and subclass (all cells)

PAMR1 RET SLIT2 DACT1 MPP4 NOTCH3

3.46e-061681086838ce47d4958ba12047882f97925eddd02f081c7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 PAMR1 FOXD4L5 SLIT2 ADAM33 LTBP4

3.83e-0617110865d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 FAT4 MDFIC SCUBE1 KRT40 KRTAP1-1

3.96e-061721086cecfe5cf20f317ea01b4604789e07a14481c4cd6
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_2|Striatum / BrainAtlas - Mouse McCarroll V32

FAM163A COL20A1 FCGBP TAS1R1 FHL3

4.13e-069810857a62a77ca83153dacff4d02d6e32104227d0980d
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocye.Tnr.Pdgfa_(Pdgfa)|Striatum / BrainAtlas - Mouse McCarroll V32

FAM163A COL20A1 FCGBP TAS1R1 FHL3

4.13e-0698108526250ea4171a0557a67505839cf79d3fe4d9d41a
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr|Striatum / BrainAtlas - Mouse McCarroll V32

FAM163A COL20A1 FCGBP TAS1R1 FHL3

4.13e-0698108542875d16ae9fcbaf988cd71be82568f2f862f2dd
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BRINP3 NOTCH2NLA NOTCH2NLB NBPF9 NBPF10 NOTCH2

5.15e-061801086b234668bf181522807470e396792e1b54890b719
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 DACT1 MPP4 SPRY4 LTBP4 PEAR1

5.31e-061811086c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAMR1 DACT1 MPP4 SPRY4 LTBP4 PEAR1

5.31e-061811086c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL20A1 SEMA5A SPRY4 LRP4 MEGF11 NOTCH2

5.48e-0618210863cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL20A1 SEMA5A SPRY4 LRP4 MEGF11 NOTCH2

5.48e-0618210865d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 FAT4 PLK2 DST NETO2 LTBP4

5.66e-0618310863427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 MYLIP FHL3 LTBP4 MUC6 PEAR1

6.02e-061851086bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLK2 LAMB1 LAMC1 SEMA5A LRP4 LTBP4

6.21e-061861086360c3e9e5c3a943e68e6939b4a47821bfc75b553
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

PCSK5 PAMR1 LAMC1 SLIT2 ADAM33 LTBP4

6.40e-0618710864ea486991f66c29728d127171a07b81404ec0b78
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMB1 SEMA5A LRRC55 STARD9 SPRY4 NOTCH3

6.40e-061871086fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PCSK5 BRINP3 SEMA5A RNF43 DACT1 FHL3

6.40e-061871086387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 KLF15 LAMB1 LAMC1 SLIT2 LTBP4

6.81e-06189108632e6d6285b258831b965281224ff2aaeecdcb5f5
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 WNT3 LDLR LY6D FCGBP LRP4

6.81e-0618910861cfc1fe27c4b57b4e52700fa8f679ce172cee5a9
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BRINP3 SEMA5A RNF43 CASZ1 DACT1 NOTCH3

6.81e-061891086f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

LAMB1 SEMA5A STARD9 SPRY4 NOTCH3 PEAR1

6.81e-061891086d7ed96add29f219183c802895fbff519b627f635
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 KLF15 LAMB1 LAMC1 SLIT2 LTBP4

6.81e-061891086385ef7bbd76c8047aeecf6542377d4213b5da5db
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 PAMR1 LRP4 ADAM33 NOTCH2 NOTCH3

6.81e-06189108645e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

FAM163A PAMR1 LAMB1 LAMC1 SLIT2 LTBP4

7.01e-06190108612992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LAMB1 DACT1 LRP4 NOTCH2 NOTCH3 PEAR1

7.01e-061901086979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LAMB1 LAMC1 SLIT2 LRP4 LTBP4

7.23e-061911086a261f0738d974784bbdd60f23092bfbcca464459
ToppCell10x5'v1-week_12-13-Endothelial-stroma-tip_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SELE LAMB1 LRRC55 OIT3 SPRY4 AGRN

7.23e-061911086cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VLDLR PAMR1 KLF15 LAMB1 SLIT2 LTBP4

7.23e-061911086cd497abed9e00e4e0becd9dbc036c6e7a60ae791
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 LAMB1 LAMC1 SLIT2 LRP4 LTBP4

7.23e-0619110866594398cc8151c73696391a43ac110c10283dab1
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAMR1 KLF15 LAMB1 LAMC1 SLIT2 LTBP4

7.23e-061911086ce80f65bd24b1c4d2152bf45248449e7a1a97e56
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VLDLR KLF15 LAMB1 SLIT2 LRP4 LTBP4

7.23e-061911086c715bbdbbf1482aad45a50a16d5232fd35a9a0bb
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VLDLR KLF15 LAMB1 SLIT2 LRP4 LTBP4

7.23e-061911086243d83cbfcc4996ad087ec6386e559e0b8662004
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAMR1 KLF15 LAMB1 LAMC1 SLIT2 LTBP4

7.23e-061911086d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VLDLR KLF15 LAMB1 SLIT2 LRP4 LTBP4

7.23e-061911086b5210de890d338602857b5907135705a507bc2b0
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT4 FRAS1 LAMB1 LAMC1 SLIT2 DST

7.23e-0619110866688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 OIT3 SPRY4 MYLIP LTBP4 PEAR1

7.45e-0619210862bfac6b3956265205ca47d06888851ed68b65999
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

FAT4 BRINP3 PAMR1 SLIT2 ADAM33 LTBP4

7.45e-061921086a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 OIT3 SPRY4 MYLIP LTBP4 PEAR1

7.45e-061921086d525f7f088a53110912600a7c9f6d33b9270d534
ToppCellILEUM-inflamed-(8)_Smooth_muscle_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FAM163A LAMB1 SEMA5A DACT1 DST LRP4

7.67e-061931086084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

FAT4 BRINP3 LAMB1 SLIT2 DST ADAM33

7.67e-061931086e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 SEMA5A VWCE LRP4 ADAM33 LTBP4

7.67e-06193108668089ba4123e2f9bea9aae0023a844b5a57bfc0e
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

FAT4 FRAS1 LAMB1 LAMC1 SLIT2 DST

7.67e-061931086acad568621ed677031797b8c2e34dafea798d681
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PLK2 OIT3 SPRY4 LTBP4 PEAR1

7.90e-061941086c8b9551b93a5aed62154b487db90130604a6125c
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CERK PLK2 RET LY6D MYLIP KDM1B

7.90e-06194108611709704079f24a730476572dc2f01e9d2226e2c
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

PCSK5 PAMR1 LAMB1 LAMC1 SLIT2 LTBP4

7.90e-061941086014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CERK PLK2 RET LY6D MYLIP KDM1B

7.90e-0619410863a1f95639d5f239f001bd67d4213e8938e7f299d
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT4 BRINP3 PAMR1 SEMA5A ADAM33 LTBP4

7.90e-061941086439d3f17c1f4736122b330e98add9292c7036a8e
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

PAMR1 LAMB1 LAMC1 SLIT2 LTBP4 NOTCH2

7.90e-061941086d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

PAMR1 LAMB1 LAMC1 SLIT2 LTBP4 NOTCH2

8.14e-061951086f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 BRINP3 PAMR1 LAMB1 SLIT2 TNN

8.14e-061951086f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 LAMB1 SEMA5A LRP2 LRP4 LTBP4

8.38e-0619610866bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 LAMB1 SEMA5A LRP2 LRP4 LTBP4

8.38e-061961086c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLK2 LAMB1 LAMC1 SEMA5A LRP4 LTBP4

8.38e-0619610861f47916c2663bd88c1e7c19c6a7688f4c7173ad2
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 LAMB1 SLIT2 DACT1 DST LTBP4

8.62e-06197108694a9603cbd3516fbcce871909693b88f20d41713
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LAMB1 LAMC1 SEMA5A SLIT2 SPRY4 NOTCH3

8.62e-061971086c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 BRINP3 PAMR1 LAMB1 SLIT2 DST

8.62e-0619710866d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCell5'-Adult-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOTCH2NLA GRN CLDN23 NOTCH2NLB NBPF10 NOTCH2

8.87e-061981086efdbac7a3a02bff4ca48841772e0c136556c2b9b
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 PAMR1 LAMB1 SLIT2 SCUBE1 TNN

8.87e-061981086300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCellNon-neuronal-Postmitotic-Mural-Mural|World / Primary Cells by Cluster

SELE LAMC1 SEMA5A OIT3 AGRN NOTCH3

8.87e-0619810869fc1035ea447a4551a66944c869c4671e17cec61
ToppCellNon-neuronal-Postmitotic-Mural|World / Primary Cells by Cluster

SELE LAMC1 SEMA5A OIT3 AGRN NOTCH3

8.87e-061981086dd38840a96171f58da243daa22b013e15a81db4a
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLK2 LAMB1 LAMC1 SEMA5A LRP4 LTBP4

8.87e-0619810864a4566f86c9365a41b4cfd1609eac09bd73b3f34
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

PCSK5 PAMR1 LAMB1 SEMA5A SLIT2 LTBP4

8.87e-061981086bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCellNon-neuronal-Postmitotic-Mural-Mural-18|World / Primary Cells by Cluster

SELE LAMC1 SEMA5A OIT3 AGRN NOTCH3

8.87e-06198108621efb7bcd24f24d20791b34e75d6f9d46a129481
ToppCell(00)_Basal-(1)_GFP|(00)_Basal / shred by cell type by condition

GRN MUC5B IDI1 LDLR LY6D NOTCH3

9.13e-061991086105b15157f35df3fdf857e306f11e4e8200e05d4
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LAMB1 SEMA5A SLIT2 DST LTBP4 LRRC15

9.13e-061991086a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DACT1 SCUBE1 STARD9 ADAM33 LTBP4 PEAR1

9.13e-0619910863835452e4848d7f7dd8651c17b746b271ef39688
ToppCell(5)_Fibroblast-G|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

FRAS1 LAMB1 LAMC1 DST SLIT1 LTBP4

9.13e-061991086b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KLF15 LAMB1 LAMC1 SLIT2 LTBP4 LRRC15

9.13e-061991086e1f1950d6f840485e263b83dc81b98910be3ae7a
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PAMR1 LAMB1 LAMC1 SLIT2 ADAM33 LTBP4

9.13e-0619910860019cfaa586a450c2e4952d1184a540561c8d0ba
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

LAMB1 LAMC1 SEMA5A SLIT2 DST LTBP4

9.13e-06199108630d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

LAMB1 SEMA5A SLIT2 DST LTBP4 LRRC15

9.13e-061991086e1849505b92820a219c5a2c35492bdd55579fb48
ToppCellBronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 SEMA5A DST STARD9 NOTCH3 PEAR1

9.13e-061991086929f809579368201331d9099d8904b6e3c41797b
ToppCellBronchial-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 SEMA5A DST STARD9 NOTCH3 PEAR1

9.13e-061991086854628ce91068093c14bd4d45ba38c41469f3549
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LAMB1 LAMC1 SEMA5A SLIT2 DST LTBP4

9.40e-0620010869b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAMR1 LAMB1 LAMC1 SLIT2 ADAM33 LTBP4

9.40e-0620010866f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

FAT4 FRAS1 LAMB1 SLIT2 DST LTBP4

9.40e-062001086aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellwk_20-22-Mesenchymal-Fibroblast-intermediate_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

BRINP3 PAMR1 LAMB1 SLIT2 DST LTBP4

9.40e-062001086d769723f8fcb37d9b86589e0c41c1d7f16393cfe
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

PCSK5 FAT4 PAMR1 LAMB1 LRP4 LTBP4

9.40e-062001086a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FAT4 FRAS1 LAMB1 SLIT2 DST LTBP4

9.40e-062001086a510deaada669e690329183e18df02870bd204b3
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 LAMB1 LAMC1 SLIT2 STARD9 ADAM33

9.40e-062001086b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SEMA5A IDI1 LDLR SPRY4 SLIT1 MEGF11

9.40e-062001086ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

LAMB1 SEMA5A SLIT2 DST LTBP4 LRRC15

9.40e-06200108644a68bacdb3d5bf563bd35952176995850933a81
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 LAMB1 LAMC1 SLIT2 STARD9 ADAM33

9.40e-0620010863dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 LAMB1 LAMC1 SLIT2 STARD9 ADAM33

9.40e-062001086c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
DrugPesticides

NBPF8 NBPF12 NOTCH2NLA LAMB1 NBPF11 NBPF1 NBPF9 NBPF10

4.78e-071501058ctd:D010575
Drug1-piperidinocyclohexanecarbonitrile

SLIT2 SLIT1 NOTCH2 NOTCH3

5.01e-06251054CID000062529
DiseaseCongenital myasthenic syndrome ib

GRN AGRN

2.69e-053892C1850792
DiseaseGlioblastoma

IFNA2 LTBP4 NOTCH2 NOTCH3

9.78e-0579894C0017636
DiseaseGiant Cell Glioblastoma

IFNA2 LTBP4 NOTCH2 NOTCH3

1.24e-0484894C0334588
Diseaseclubfoot (implicated_via_orthology)

FRAS1 RET

1.34e-046892DOID:11836 (implicated_via_orthology)
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH2 NOTCH3

1.87e-047892DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH2 NOTCH3

1.87e-047892DOID:3620 (implicated_via_orthology)
Diseasebipolar II disorder

SLIT1 ADGRE1

2.49e-048892EFO_0009964
DiseaseUnilateral agenesis of kidney

FRAS1 RET

2.49e-048892C0266294
DiseaseCarcinoma, Transitional Cell

IFNA2 KMT2A ESPL1

2.60e-0441893C0007138
DiseaseHereditary Diffuse Gastric Cancer

FAT4 RNF43 FCGBP KMT2A MUC6 NOTCH2

2.65e-04293896C1708349
DiseaseStomach Neoplasms

FAT4 RNF43 FCGBP KMT2A MUC6 NOTCH2

2.85e-04297896C0038356
DiseaseMalignant neoplasm of stomach

FAT4 RNF43 FCGBP KMT2A MUC6 NOTCH2

3.01e-04300896C0024623
DiseaseGlioblastoma Multiforme

IFNA2 LTBP4 NOTCH2 NOTCH3

3.62e-04111894C1621958
Diseasedementia (is_implicated_in)

VLDLR GRN

5.82e-0412892DOID:1307 (is_implicated_in)
Diseaseautistic disorder (is_marker_for)

VLDLR GRN

5.82e-0412892DOID:12849 (is_marker_for)
DiseaseBladder Neoplasm

IFNA2 KMT2A ESPL1 NOTCH2

8.67e-04140894C0005695
DiseaseMalignant neoplasm of urinary bladder

IFNA2 KMT2A ESPL1 NOTCH2

8.91e-04141894C0005684
Diseasecaffeine measurement

LAMC1 MEGF11

9.21e-0415892EFO_0021177
Diseaseresponse to statin, LDL cholesterol change measurement

LDLR MYLIP

9.21e-0415892EFO_0007804, GO_0036273
Diseasebreast carcinoma

VLDLR PLK2 WNT3 LAMC1 CASZ1 MPP4 SPRY4 NBPF10 HABP2 NOTCH2

9.95e-0410198910EFO_0000305
DiseaseMyasthenic Syndromes, Congenital, Slow Channel

LRP4 AGRN

1.05e-0316892C0751885
DiseaseDementia

GRN NOTCH3

1.19e-0317892C0497327
DiseaseCongenital Myasthenic Syndromes, Postsynaptic

LRP4 AGRN

1.19e-0317892C0751883
DiseaseColorectal Carcinoma

LAMC1 RET RNF43 IFNA2 DACT1 CCDC62 LRP2 FHL3

1.28e-03702898C0009402
DiseaseParoxysmal atrial fibrillation

SELE WNT3 CASZ1 KDM1B

1.29e-03156894C0235480
Diseasefamilial atrial fibrillation

SELE WNT3 CASZ1 KDM1B

1.29e-03156894C3468561
DiseasePersistent atrial fibrillation

SELE WNT3 CASZ1 KDM1B

1.29e-03156894C2585653
Diseasecancer (implicated_via_orthology)

RET IDI1 DST NOTCH2 NOTCH3

1.33e-03268895DOID:162 (implicated_via_orthology)
DiseaseAtrial Fibrillation

SELE WNT3 CASZ1 KDM1B

1.42e-03160894C0004238
Diseasewellbeing measurement, alcohol consumption measurement

DACT1 DST USH2A

1.47e-0374893EFO_0007869, EFO_0007878
DiseaseCongenital Myasthenic Syndromes, Presynaptic

LRP4 AGRN

1.49e-0319892C0751884
Diseaseprimary ciliary dyskinesia (implicated_via_orthology)

PCSK5 SLIT2

1.49e-0319892DOID:9562 (implicated_via_orthology)
DiseaseColorectal Neoplasms

RET RNF43 IFNA2 DACT1 FHL3

1.54e-03277895C0009404
Diseaseunipolar depression, bipolar disorder, schizophrenia

PCSK5 MDFIC

1.65e-0320892EFO_0003761, MONDO_0004985, MONDO_0005090
DiseaseHematochezia, response to radiation

LAMB1 LRRC55

1.65e-0320892GO_0009314, HP_0002573
DiseaseLung diseases

PCSK5 RET LTBP4

1.71e-0378893C0024115
DiseaseLeukemia, Myelocytic, Acute

SPRY4 KMT2A AGRN NOTCH2

1.89e-03173894C0023467
Diseaseclinical and behavioural ideal cardiovascular health

BRINP3 LDLR

2.18e-0323892EFO_0007654
DiseaseMyasthenic Syndromes, Congenital

LRP4 AGRN

2.38e-0324892C0751882
Diseasebrain cancer (implicated_via_orthology)

NOTCH2 NOTCH3

2.79e-0326892DOID:1319 (implicated_via_orthology)
Diseasetotal cortical area measurement

WNT3 TFDP2 DACT1

2.92e-0394893EFO_0008381
DiseaseSquamous cell carcinoma of esophagus

FAT4 NOTCH2 NOTCH3

3.01e-0395893C0279626

Protein segments in the cluster

PeptideGeneStartEntry
LGSFSEETHSCTCPN

BRINP3

416

Q76B58
SGCTCSESICGTQHD

CCDC62

551

Q6P9F0
ECTSGQNPCHSSTHC

ADGRE2

166

Q9UHX3
CPFSGTSTHFHCLRC

CASZ1

1506

Q86V15
PCSCLSCHSSQSAAA

EVX2

386

Q03828
HSCIFTVSGTSSCCP

GRN

71

P28799
TCHNLVGGFSCSCPD

FAT4

3876

Q6V0I7
DPCSNVTCSFGSTCA

AGRN

246

O00468
DCDLPEFCTGTSSHC

ADAM33

481

Q9BZ11
GDCLCHQCSPTTSSF

DISP1

1291

Q96F81
TLDVGCFSTHCVSGC

MUC5B

821

Q9HC84
MSGFTCPHCTECTSV

NUBP2

191

Q9Y5Y2
CPHCTECTSVFSRGG

NUBP2

196

Q9Y5Y2
TDACLSHPCANGSTC

NOTCH2NLA

106

Q7Z3S9
NPQHSCSSSCTFGCF

MUC6

321

Q6W4X9
CSSSCTFGCFCPEGT

MUC6

326

Q6W4X9
DACLSHPCANGSTCT

NOTCH2NLB

146

P0DPK3
DACLSHPCANGSTCT

NOTCH2

146

Q04721
ASCSAEDGACHCTPG

MEGF11

716

A6BM72
NSTCDHVTGTCYCSP

MEGF11

801

A6BM72
MTSDCSSTHCSPESC

KRT40

1

Q6A162
HSDAGTSCPVLCTCR

LRRC55

31

Q6ZSA7
SCASCSGPTPSHCTA

FRAS1

611

Q86XX4
SQKTGSSPEDCCVHC

MDFIC

156

Q9P1T7
SCFHCRGSGSATCSL

GRXCR2

196

A6NFK2
LLELSCCHSCPFSST

MMS19

741

Q96T76
CCHSCPFSSTAAAKC

MMS19

746

Q96T76
CTATPSSFNKCHCGE

DST

2061

Q03001
ATATCSSDHQACCIP

FOXD4L4

351

Q8WXT5
ATATCSSDHQACCIP

FOXD4L3

351

Q6VB84
ETCTGPGHDECSSCQ

PCSK5

1136

Q92824
QPCHSSCKTCNGSAT

PCSK5

1181

Q92824
SSPCRTCEGNATNCH

PCSK5

1281

Q92824
HGSCSDTSECTCAPG

OIT3

156

Q8WWZ8
CAHEAVCSPQTGACT

PEAR1

496

Q5VY43
FSCTCPSGFSGSTCQ

NOTCH3

491

Q9UM47
CGPGTCTDHVASFTC

NOTCH3

896

Q9UM47
CTDHVASFTCTCPPG

NOTCH3

901

Q9UM47
HLSPLHASVCCTGSC

MPP4

391

Q96JB8
NSTFCPCGHTVCCES

MYLIP

396

Q8WY64
AACTNTSCSGHGECV

SELE

141

P16581
SCFAESGQCSCRPHM

LAMB1

521

P07942
SASSLCAASPPNCCH

KRTAP4-16

11

G5E9R7
STGGTCDSSCCQPSC

KRTAP1-1

61

Q07627
TSASCSCPTCVGEHM

LYPD4

136

Q6UWN0
TCSSSAFTCGHGECI

LRP2

1066

P98164
CALHTCSPTAFTCAN

LRP2

2736

P98164
GTCSDSVVHSCDLCG

OVOL2

111

Q9BRP0
ECAITCSNSHSPCDS

NBPF1

206

Q3BBV0
TDACLSHPCANGSTC

NOTCH2NLC

106

P0DPK4
CSPECSSPCSSASHS

LRRC58

331

Q96CX6
GDCLVHGSTFTCSCL

HABP2

86

Q14520
HNCFSCARCSTSLVG

FHL3

246

Q13643
SHSPTCDCSLCASPV

ESPL1

1141

Q14674
TFPGCFTNTCCSHPL

IDI1

76

Q13907
AGCTATCPVCFASAS

KDM1B

56

Q8NB78
SCHSSTCFCSPLEAT

DACT1

186

Q9NYF0
TCPAFVSACSCSSET

COL20A1

1056

Q9P218
LVSCESSSCGPHEAC

FCGBP

1221

Q9Y6R7
GHICSSHPSCCCTVS

CERK

481

Q8TCT0
SSFAPCSVTTCCSLG

GIMD1

36

P0DJR0
CKSSCSVGCDLPQTH

IFNA2

16

P01563
CTSSSNCKHSVVCPA

LY6D

26

Q14210
HGECLNTDGSFACTC

LTBP4

891

Q8N2S1
SCSSPDSQALCSCYG

KLF15

51

Q9UIH9
ATVGCCLTSCTSNYH

KMT2A

1941

Q03164
CVPTCSEDSSSCCQH

KRTAP10-5

141

P60370
SEDSSSCCQHSSCQP

KRTAP10-5

146

P60370
ACEPSACQSGYTSSC

KRTAP10-10

56

P60014
CCESEPSGASGCCHS

LCE2D

91

Q5TA82
NNEACSSCHCSPVGS

LAMC1

391

P11047
SSCHCSPVGSLSTQC

LAMC1

396

P11047
GCTPCFCFGHSSVCT

LAMC1

491

P11047
CGSSCDQSSSCAPVY

KRTAP9-4

86

Q9BYQ2
CVFSSCNTTCCVPSH

KRTAP29-1

231

A8MX34
QPCGVAASHCTTCSP

FAM163A

86

Q96GL9
SQTTVPCVTHAGFCC

DGLUCY

146

Q7Z3D6
ANCFDCPGCMHTLST

DCTN4

71

Q9UJW0
SCEDTDTGPTCGCHQ

SCUBE1

216

Q8IWY4
ACAECFTAVSHSSSP

PPP4R1L

221

Q9P1A2
SCSTHPCDSSLPCDS

CLDN23

276

Q96B33
ITACSSSPCFHDGTC

PAMR1

236

Q6UXH9
TGCLPCSCHTTGAVN

USH2A

946

O75445
EGSCADHPCSCSRSN

SPRY4

216

Q9C004
AYHGCPSECTCSRAS

LRRC15

21

Q8TF66
ECAITCSNSHGPCDS

NBPF8

171

Q3BBV2
ECAITCSNSHGPCDS

NBPF9

206

P0DPF3
ECAITCSNSHGPCDS

NBPF10

206

Q6P3W6
ECAITCSNSHGPCDS

NBPF11

206

Q86T75
ECAITCSNSHGPCDS

NBPF12

206

Q5TAG4
ATATCSSDHQACCIP

FOXD4L5

351

Q5VV16
ATATCSSDHQACCIP

FOXD4L6

351

Q3SYB3
DSGSSCSSAPVCAIC

RNF43

261

Q68DV7
PCTSSTFFCHSNMCI

NETO2

296

Q8NC67
AYSHRASLGSCCCSP

STARD9

4456

Q9P2P6
ASHCSESRGETPCSF

TFDP2

416

Q14188
PCTHTDGSAVGSCLC

SEMA5A

551

Q13591
CLTSSVCPEHSDCVN

ADGRE1

136

Q14246
QCPSFSHYSVCTSSC

TECTA

596

O75443
SHYSVCTSSCPDTCS

TECTA

601

O75443
SCCWAFACHSTESSP

TAS1R1

16

Q7RTX1
LASCVKSDHSCSPCA

TSPAN13

141

O95857
SPAHTCDQCAISFSS

ZFHX2

1766

Q9C0A1
HCSGHGTFSLETCSC

TNN

141

Q9UQP3
GTFSLETCSCHCEEG

TNN

146

Q9UQP3
SCHNTVGSFLCTCRP

VWCE

236

Q96DN2
CAEGTSTICGCDSHH

WNT3

131

P56703
QCSCSGSTVDCHGLA

SLIT2

31

O94813
STCSPSTKTCPDGHC

RET

556

P07949
SECPLACSSSLHCAS

TRPC5

916

Q9UL62
QGFTPDRLSSSCCHT

PLK2

336

Q9NYY3
CFSPSGHILASCSTD

WDSUB1

61

Q8N9V3
SRHITCCSCESPGDV

nan

76

Q6ZS46
ALCTCTGTTVDCHGT

SLIT1

36

O75093
QSPAVCSSSVCCSHC

TRIM66

311

O15016
CSSSVCCSHCSPVSP

TRIM66

316

O15016
SGSSITCCFTCFDQG

WDR87

201

Q6ZQQ6
HHDCSVCGKSFTCNS

ZNF202

396

O95125
ISESSSCPSCGQTCH

PRR11

136

Q96HE9
TCCSSSSSCPAHFEG

WBP1

156

Q96G27
VGLACCCSHTTAEAS

TXNRD3NB

31

Q6F5E7
CNDCGKSFTHSSTFC

ZNF814

746

B7Z6K7
PTCGAHEFQCSTSSC

VLDLR

191

P98155
LTCGPASFQCNSSTC

LDLR

146

P01130
SSPECACGRSHFTCA

LRP4

21

O75096