Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionserine-type endopeptidase activity

TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F OVCH1 PRSS53 TMPRSS11D PRSS42P TMPRSS2 TMPRSS7

1.97e-1019010012GO:0004252
GeneOntologyMolecularFunctionendopeptidase activity

EEF1AKMT4-ECE2 TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F ECE1 OVCH1 PRSS53 ADAMTS7 TMPRSS11D PRSS42P TMPRSS2 ADAMTS14 TMPRSS7

4.17e-1043010016GO:0004175
GeneOntologyMolecularFunctionserine-type peptidase activity

TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F OVCH1 PRSS53 TMPRSS11D PRSS42P TMPRSS2 TMPRSS7

5.29e-1020710012GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F OVCH1 PRSS53 TMPRSS11D PRSS42P TMPRSS2 TMPRSS7

6.95e-1021210012GO:0017171
GeneOntologyMolecularFunctionpeptidase activity

EEF1AKMT4-ECE2 TMPRSS15 TMPRSS6 AMZ1 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F ECE1 OVCH1 PRSS53 ADAMTS7 TMPRSS11D PRSS42P TMPRSS2 ADAMTS14 TMPRSS7

2.47e-0865410017GO:0008233
GeneOntologyMolecularFunctionproline-rich region binding

ITSN1 TCERG1 GIGYF2

1.52e-04211003GO:0070064
GeneOntologyMolecularFunctionmetalloendopeptidase activity

EEF1AKMT4-ECE2 TMPRSS6 ECE1 ADAMTS7 ADAMTS14

3.44e-041201005GO:0004222
GeneOntologyMolecularFunctionmetallopeptidase activity

EEF1AKMT4-ECE2 TMPRSS6 AMZ1 ECE1 ADAMTS7 ADAMTS14

5.11e-042001006GO:0008237
GeneOntologyMolecularFunctionsymporter activity

SLC16A13 SLC16A9 SLC16A3 SLC13A5 SLC39A5

9.50e-041501005GO:0015293
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLC16A13 SLC16A9 SLC16A6 SLC16A3

1.09e-03901004GO:0008028
GeneOntologyBiologicalProcessclathrin-dependent synaptic vesicle endocytosis

ITSN1 ITSN2

2.33e-0521002GO:0150007
DomainTRYPSIN_HIS

TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F OVCH1 PRSS53 TMPRSS11D PRSS42P TMPRSS2 TMPRSS7

1.98e-131039712IPR018114
DomainTRYPSIN_SER

TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F OVCH1 PRSS53 TMPRSS11D PRSS42P TMPRSS2 TMPRSS7

2.82e-131069712PS00135
DomainTRYPSIN_HIS

TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F OVCH1 PRSS53 TMPRSS11D PRSS42P TMPRSS2 TMPRSS7

3.16e-131079712PS00134
DomainPeptidase_S1A

TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F OVCH1 PRSS53 TMPRSS11D PRSS42P TMPRSS2 TMPRSS7

6.14e-131139712IPR001314
DomainTRYPSIN_DOM

TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F OVCH1 PRSS53 TMPRSS11D PRSS42P TMPRSS2 TMPRSS7

7.60e-131159712PS50240
DomainTryp_SPc

TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F OVCH1 PRSS53 TMPRSS11D PRSS42P TMPRSS2 TMPRSS7

9.36e-131179712SM00020
DomainTRYPSIN_SER

TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F OVCH1 PRSS53 TMPRSS11D TMPRSS2 TMPRSS7

1.23e-12909711IPR033116
DomainTrypsin

TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F OVCH1 PRSS53 TMPRSS11D PRSS42P TMPRSS2 TMPRSS7

1.41e-121219712PF00089
DomainTrypsin_dom

TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F OVCH1 PRSS53 TMPRSS11D PRSS42P TMPRSS2 TMPRSS7

1.41e-121219712IPR001254
DomainPeptidase_S1_PA

TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F OVCH1 PRSS53 TMPRSS11D PRSS42P TMPRSS2 TMPRSS7

1.71e-121239712IPR009003
Domain-

TMPRSS15 TMPRSS6 TMPRSS11E TMPRSS11F TMPRSS11D TMPRSS7

8.09e-11159763.30.70.960
DomainSEA

TMPRSS15 TMPRSS6 TMPRSS11E TMPRSS11F TMPRSS11D TMPRSS7

1.17e-0922976PF01390
DomainSEA

TMPRSS15 TMPRSS6 TMPRSS11E TMPRSS11F TMPRSS11D TMPRSS7

1.58e-0923976PS50024
DomainSEA_dom

TMPRSS15 TMPRSS6 TMPRSS11E TMPRSS11F TMPRSS11D TMPRSS7

1.58e-0923976IPR000082
DomainPept_S1A_HAT/DESC1

TMPRSS11E TMPRSS11F TMPRSS11D

1.35e-065973IPR017329
Domain-

TMPRSS15 TMPRSS6 MAMDC4 TMPRSS2 TMPRSS7

3.94e-06469754.10.400.10
DomainSRCR_2

TMPRSS15 TMPRSS5 TMPRSS2

4.68e-067973PF15494
DomainLDLRA_1

TMPRSS15 TMPRSS6 MAMDC4 TMPRSS2 TMPRSS7

4.89e-0648975PS01209
DomainLDLRA_2

TMPRSS15 TMPRSS6 MAMDC4 TMPRSS2 TMPRSS7

5.42e-0649975PS50068
DomainLDrepeatLR_classA_rpt

TMPRSS15 TMPRSS6 MAMDC4 TMPRSS2 TMPRSS7

5.42e-0649975IPR002172
DomainLDLa

TMPRSS15 TMPRSS6 MAMDC4 TMPRSS2 TMPRSS7

5.42e-0649975SM00192
DomainPH_13

ITSN1 ITSN2

2.67e-052972PF16652
DomainSEA

TMPRSS15 TMPRSS11F TMPRSS11D

4.74e-0514973SM00200
DomainSH3_9

ITSN1 SRMS GAS7 ITSN2 MAP3K10

5.33e-0578975PF14604
DomainLDLR_class-A_CS

TMPRSS15 MAMDC4 TMPRSS2 TMPRSS7

5.41e-0540974IPR023415
DomainSH3_2

MIA3 ITSN1 SRMS ITSN2 MAP3K10

8.51e-0586975IPR011511
DomainSH3_2

MIA3 ITSN1 SRMS ITSN2 MAP3K10

8.51e-0586975PF07653
DomainLdl_recept_a

TMPRSS15 TMPRSS6 MAMDC4 TMPRSS7

8.65e-0545974PF00057
DomainPLAC

ADAMTSL1 ADAMTS7 ADAMTS14

1.24e-0419973PS50900
DomainPLAC

ADAMTSL1 ADAMTS7 ADAMTS14

1.24e-0419973IPR010909
DomainCUB

TMPRSS15 TMPRSS6 OVCH1 TMPRSS7

1.31e-0450974SM00042
DomainSH3

MIA3 ITSN1 OBSCN SRMS GAS7 ITSN2 MAP3K10

1.34e-04216977SM00326
DomainSH3

MIA3 ITSN1 OBSCN SRMS GAS7 ITSN2 MAP3K10

1.34e-04216977PS50002
DomainSH3_domain

MIA3 ITSN1 OBSCN SRMS GAS7 ITSN2 MAP3K10

1.50e-04220977IPR001452
Domain-

TMPRSS15 TMPRSS6 OVCH1 TMPRSS7

1.53e-04529742.60.120.290
DomainWWE

DTX1 DTX2

1.59e-044972SM00678
DomainWWE-dom_subgr

DTX1 DTX2

1.59e-044972IPR018123
DomainCUB

TMPRSS15 TMPRSS6 OVCH1 TMPRSS7

1.65e-0453974PS01180
DomainCUB_dom

TMPRSS15 TMPRSS6 OVCH1 TMPRSS7

2.19e-0457974IPR000859
DomainPeptidase_M12B_ADAM-TS

ADAMTSL1 ADAMTS7 ADAMTS14

2.54e-0424973IPR013273
Domain-

TMPRSS15 TMPRSS5 TMPRSS2

2.87e-04259733.10.250.10
DomainSRCR_1

TMPRSS15 TMPRSS5 TMPRSS2

3.24e-0426973PS00420
DomainSRCR_2

TMPRSS15 TMPRSS5 TMPRSS2

3.24e-0426973PS50287
DomainSRCR-like_dom

TMPRSS15 TMPRSS5 TMPRSS2

3.24e-0426973IPR017448
DomainSRCR

TMPRSS15 TMPRSS5 TMPRSS2

3.63e-0427973IPR001190
DomainPkinase_Tyr

SRMS TYK2 GUCY2D MAP3K10 EPHA4

5.64e-04129975PF07714
DomainMFS_1

SLC16A13 SLC16A9 SLC16A6 SLC16A3

6.92e-0477974PF07690
DomainMFS

SLC16A13 SLC16A9 SLC16A6 SLC16A3

6.92e-0477974IPR011701
DomainSer-Thr/Tyr_kinase_cat_dom

SRMS TYK2 GUCY2D MAP3K10 EPHA4

7.66e-04138975IPR001245
DomainEF-hand_4

ITSN1 ITSN2

1.17e-0310972PF12763
DomainEH

ITSN1 ITSN2

1.42e-0311972PS50031
DomainEH

ITSN1 ITSN2

1.42e-0311972SM00027
DomainEH_dom

ITSN1 ITSN2

1.42e-0311972IPR000261
DomainPROTEIN_KINASE_TYR

OBSCN SRMS TYK2 EPHA4

1.64e-0397974PS00109
DomainTyr_kinase_AS

OBSCN SRMS TYK2 EPHA4

1.64e-0397974IPR008266
DomainZINC_PROTEASE

AMZ1 ECE1 ADAMTS7 ADAMTS14

1.70e-0398974PS00142
DomainWWE

DTX1 DTX2

1.70e-0312972PS50918
DomainWWE

DTX1 DTX2

1.70e-0312972PF02825
DomainWWE-dom

DTX1 DTX2

1.70e-0312972IPR004170
DomainCUB

TMPRSS15 OVCH1 TMPRSS7

2.10e-0349973PF00431
DomainMFS

SLC16A13 SLC16A9 SLC16A6 SLC16A3

2.43e-03108974PS50850
DomainMAM_1

TMPRSS15 MAMDC4

3.06e-0316972PS00740
DomainMAM

TMPRSS15 MAMDC4

3.45e-0317972SM00137
DomainMAM

TMPRSS15 MAMDC4

3.87e-0318972PF00629
DomainMAM_dom

TMPRSS15 MAMDC4

3.87e-0318972IPR000998
DomainMAM_2

TMPRSS15 MAMDC4

3.87e-0318972PS50060
DomainIG_LIKE

ROBO4 ADAMTSL1 OSCAR OBSCN HAPLN4 FCGRT ICAM5 FCAMR

4.04e-03491978PS50835
DomainTSP_1

ADAMTSL1 ADAMTS7 ADAMTS14

4.30e-0363973PF00090
DomainIg-like_dom

ROBO4 ADAMTSL1 OSCAR OBSCN HAPLN4 FCGRT ICAM5 FCAMR

4.66e-03503978IPR007110
DomainTSP1

ADAMTSL1 ADAMTS7 ADAMTS14

4.70e-0365973SM00209
DomainTSP1_rpt

ADAMTSL1 ADAMTS7 ADAMTS14

4.70e-0365973IPR000884
DomainTSP1

ADAMTSL1 ADAMTS7 ADAMTS14

4.70e-0365973PS50092
Pubmed

The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond.

SLC16A13 SLC16A9 SLC16A6 SLC16A3

7.10e-0814103412739169
Pubmed

Iterative, multiplexed CRISPR-mediated gene editing for functional analysis of complex protease gene clusters.

TMPRSS11E TMPRSS11F TMPRSS11D

8.75e-077103331501243
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CRYBG2 GBF1 MAN2B1 OBSCN SREBF1 POMGNT1 ECE1 RNF43 TYK2 ADAMTS7 HPS6 SLC35A2 DTX2 HERC1 IQCE

9.26e-0711051031535748872
Pubmed

Phenotypic analysis of mice lacking the Tmprss2-encoded protease.

TMPRSS6 TMPRSS11E TMPRSS2

5.44e-0612103316428450
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

DTX1 DLL3 DTX2

5.44e-0612103315465494
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

EEF1AKMT4-ECE2 SLC25A27 ROBO4 ADAMTSL1 MIA3 IZUMO4 TMPRSS6 TMPRSS11E PRSS22 POMGNT1 MAMDC4 PRSS53 KAT14

7.10e-069851031312975309
Pubmed

Intersectin deficiency impairs cortico-striatal neurotransmission and causes obsessive-compulsive behaviors in mice.

ITSN1 ITSN2

8.69e-062103237603735
Pubmed

Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts.

TMPRSS11D TMPRSS2

8.69e-062103222558251
Pubmed

Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain.

ITSN1 ITSN2

8.69e-062103231031201
Pubmed

Intersectin associates with synapsin and regulates its nanoscale localization and function.

ITSN1 ITSN2

8.69e-062103229078407
Pubmed

Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium.

TMPRSS11D TMPRSS2

8.69e-062103216973594
Pubmed

Adaptor proteins intersectin 1 and 2 bind similar proline-rich ligands but are differentially recognized by SH2 domain-containing proteins.

ITSN1 ITSN2

8.69e-062103223936226
Pubmed

Vertebrate intersectin1 is repurposed to facilitate cortical midline connectivity and higher order cognition.

ITSN1 ITSN2

8.69e-062103223447614
Pubmed

The human intersectin genes and their spliced variants are differentially expressed.

ITSN1 ITSN2

8.69e-062103211690630
Pubmed

A mouse knockout library for secreted and transmembrane proteins.

ROBO4 ADAMTSL1 MIA3 IZUMO4 TMPRSS6 PRSS22 POMGNT1 ITGA2B TMPRSS2

9.59e-06460103920562862
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

MIA3 MAN2B1 SREBF1 ECE1 TYK2 MOGS TCERG1 WDR6 AP5B1 GIGYF2

2.41e-056501031038777146
Pubmed

Behavioral analysis in mice deficient for GAREM2 (Grb2-associated regulator of Erk/MAPK subtype2) that is a subtype of highly expressing in the brain.

ITSN1 ITSN2

2.60e-053103231718706
Pubmed

Matriptase, HAT, and TMPRSS2 activate the hemagglutinin of H9N2 influenza A viruses.

TMPRSS11D TMPRSS2

2.60e-053103223192872
Pubmed

Intersectin 2, a new multimodular protein involved in clathrin-mediated endocytosis.

ITSN1 ITSN2

2.60e-053103210922467
Pubmed

Upregulation of WDR6 drives hepatic de novo lipogenesis in insulin resistance in mice.

SREBF1 WDR6

2.60e-053103237735236
Pubmed

Cellular expression of the monocarboxylate transporter (MCT) family in the placenta of mice.

SLC16A9 SLC16A3

2.60e-053103220022372
Pubmed

T cells develop normally in the absence of both Deltex1 and Deltex2.

DTX1 DTX2

2.60e-053103216923970
Pubmed

The tissue expression of MCT3, MCT8, and MCT9 genes in women with breast cancer.

SLC16A9 SLC16A3

2.60e-053103234097251
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

GBF1 DTX1 ITSN1 SCAMP3 LINC00696 AP5B1 IQCE TECPR1

4.37e-05430103835044719
Pubmed

Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis.

DTX1 DTX2

5.19e-054103211226752
Pubmed

TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1.

TMPRSS11E TMPRSS11D

5.19e-054103229976755
Pubmed

Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats.

DTX1 DTX2

5.19e-05410327671825
Pubmed

Mammalian verprolin CR16 acts as a modulator of ITSN scaffold proteins association with actin.

ITSN1 ITSN2

5.19e-054103228161632
Pubmed

The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation.

SLC16A6 SLC16A3

5.19e-054103210510291
Pubmed

A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry.

TMPRSS11D TMPRSS2

5.19e-054103221068237
Pubmed

The EH and SH3 domain Ese proteins regulate endocytosis by linking to dynamin and Eps15.

ITSN1 ITSN2

5.19e-054103210064583
Pubmed

TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein.

TMPRSS11D TMPRSS2

8.64e-055103224227843
Pubmed

Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor.

DTX1 DTX2

8.64e-055103211564735
Pubmed

Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past.

SLC16A6 SLC16A3

8.64e-05510329425115
Pubmed

Polymorphisms in ACE1, TMPRSS2, IFIH1, IFNAR2, and TYK2 Genes Are Associated with Worse Clinical Outcomes in COVID-19.

TYK2 TMPRSS2

8.64e-055103236672770
Pubmed

Human and mouse proteases: a comparative genomic approach.

OVCH1 FREM1 PRSS42P TMPRSS7

1.01e-0481103412838346
Pubmed

HIV-1 envelope protein gp120 affects phenotype and function of monocytes in vitro.

FCGRT FCAMR

1.29e-04610328145026
Pubmed

SCAMP1 function in endocytosis.

ITSN1 SCAMP3

1.29e-046103210777571
Pubmed

Genotype versus phenotype: conflicting results in mapping a lung tumor susceptibility locus to the G7c recombination interval in the mouse MHC class III region.

VWA7 VARS1

1.29e-046103211797099
Pubmed

Molecular analysis of the major MHC recombinational hot spot located within the G7c gene of the murine class III region that is involved in disease susceptibility.

VWA7 VARS1

1.81e-04710329551980
Pubmed

Feedback loops comprising Dll1, Dll3 and Mesp2, and differential involvement of Psen1 are essential for rostrocaudal patterning of somites.

DLL3 EPHA4

1.81e-047103212900443
Pubmed

EHSH1/intersectin, a protein that contains EH and SH3 domains and binds to dynamin and SNAP-25. A protein connection between exocytosis and endocytosis?

ITSN1 ITSN2

1.81e-047103210373452
Pubmed

Early mesodermal phenotypes in splotch suggest a role for Pax3 in the formation of epithelial somites.

DLL3 EPHA4

1.81e-047103211747084
Pubmed

The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity.

DTX1 DTX2

2.40e-048103212670957
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

ROBO4 GBF1 PRSS42P GIGYF2 SLC13A5 HERC1 EPHA4

2.61e-04420103728065597
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

MIA3 ITSN1 WDR6 HPS6 ITSN2 GIGYF2 DTX2 HERC1

4.43e-04604103838803224
Pubmed

Activator-Mediator binding regulates Mediator-cofactor interactions.

SREBF1 TADA2B

4.69e-0411103220534441
Pubmed

FCHo proteins are nucleators of clathrin-mediated endocytosis.

ITSN1 ITSN2

6.63e-0413103220448150
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

GRWD1 OVCH1 GIGYF2 HERC1 VARS1

6.77e-04234103536243803
Pubmed

Cloning of ligand targets: systematic isolation of SH3 domain-containing proteins.

ITSN1 ITSN2

8.89e-041510329630982
Pubmed

Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse.

DLL3 EPHA4

8.89e-0415103210330372
Pubmed

Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton.

DLL3 EPHA4

8.89e-0415103219520072
Pubmed

RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.

OBSCN RNF43 PPP6C WDR6

1.00e-03148103435676246
Pubmed

Tcf7l2 transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus.

GAS7 EPHA4

1.01e-0316103231872525
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

MIA3 ITSN1 RNF43 TCERG1 GIGYF2

1.14e-03263103534702444
Pubmed

The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments.

DLL3 EPHA4

1.15e-0317103215155583
Pubmed

Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells.

MAN2B1 MOGS

1.15e-031710322355006
Pubmed

Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.

RLN3 PTH2R GHRHR

1.20e-0370103312036966
Pubmed

Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.

DLL3 EPHA4

1.29e-0318103221147753
Pubmed

JMJD6 negatively regulates cytosolic RNA induced antiviral signaling by recruiting RNF5 to promote activated IRF3 K48 ubiquitination.

JMJD6 WDR6

1.29e-0318103233684176
Pubmed

Ebf1 controls early cell differentiation in the embryonic striatum.

DLL3 EPHA4

1.29e-0318103210556054
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTSL1 ADAMTS7 ADAMTS14

1.46e-0375103320637190
Pubmed

Glycosylation inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin.

MAN2B1 MOGS

1.59e-0320103212560567
Pubmed

Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice.

TMPRSS2 TMPRSS7

1.76e-0321103219592578
Pubmed

A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.

ECE1 GUCY2D DLL3

1.82e-0381103316110338
Pubmed

Crosstalk between lysine methylation and phosphorylation of ATG16L1 dictates the apoptosis of hypoxia/reoxygenation-induced cardiomyocytes.

ABHD5 JMJD6

1.93e-0322103229634390
Pubmed

Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response.

MAN2B1 MOGS

1.93e-032210328673525
Pubmed

Effect of various glycosidase treatments on the resistance of the HIV-1 envelope to degradation.

MAN2B1 MOGS

1.93e-032210329109416
Pubmed

Folding of the human immunodeficiency virus type 1 envelope glycoprotein in the endoplasmic reticulum.

MAN2B1 MOGS

1.93e-0322103211530211
Pubmed

Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.

CRYBG2 ADAMTSL1 FCAMR

2.02e-0384103315203218
Pubmed

Role of asparagine-linked glycosylation in human immunodeficiency virus type 1 transmembrane envelope function.

MAN2B1 MOGS

2.11e-032310321736542
Pubmed

Functional role of the glycan cluster of the human immunodeficiency virus type 1 transmembrane glycoprotein (gp41) ectodomain.

MAN2B1 MOGS

2.11e-032310328093218
Pubmed

Glycosylation inhibitors block the expression of LAV/HTLV-III (HIV) glycoproteins.

MAN2B1 MOGS

2.11e-032310323099781
Pubmed

The double-histone-acetyltransferase complex ATAC is essential for mammalian development.

TADA2B KAT14

2.11e-0323103219103755
Pubmed

Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1.

MAN2B1 MOGS

2.11e-032310323264072
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

GPRASP1 MIA3 ITSN1 ARMCX4 PPP6C ICAM5 PPP1R3F GIGYF2 EPHA4

2.27e-03963103928671696
Pubmed

Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events.

GPRASP1 ARMCX4

2.30e-0324103216221301
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

MAN2B1 SCAMP3 ITGA2B ECE1 PPP6C ICAM5 VARS1

2.36e-03613103722268729
Pubmed

Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.

ADAMTSL1 PTH2R TMPRSS2

2.38e-0389103324529757
Pubmed

Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.

TYK2 EPHA4

2.49e-0325103215254900
Pubmed

Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins.

MAN2B1 MOGS

2.49e-032510322283726
Pubmed

Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.

MAN2B1 MOGS

2.69e-032610328218172
Pubmed

Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.

TADA2B KAT14

2.90e-0327103218838386
Cytoband4q13.2

TMPRSS11E TMPRSS11F TMPRSS11D

4.71e-053110334q13.2
Cytoband7p22.3

AMZ1 PSMG3-AS1 IQCE

6.24e-053410337p22.3
Cytoband17p13.1

SLC16A13 GAS7 GUCY2D SLC13A5

1.51e-04118103417p13.1
CytobandEnsembl 112 genes in cytogenetic band chr19p13

CPAMD8 IZUMO4 MAN2B1 HAPLN4 RLN3 TYK2 CLEC17A ICAM5

4.45e-047971038chr19p13
CytobandEnsembl 112 genes in cytogenetic band chr4q13

TMPRSS11E TMPRSS11F NPFFR2 TMPRSS11D

4.47e-041571034chr4q13
GeneFamilyProteases, serine

TMPRSS15 TMPRSS6 TMPRSS11E PRSS22 TMPRSS5 TMPRSS11F PRSS53 TMPRSS11D PRSS42P TMPRSS2 TMPRSS7

1.29e-15637411738
GeneFamilySolute carriers

SLC25A27 SLC16A13 SLC16A9 SLC16A6 SLC16A3 SLC35A2 SLC13A5 SLC39A5

2.07e-04395748752
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ITSN1 OBSCN ITSN2

2.50e-0366743722
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS7 ADAMTS14

2.70e-031974250
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

MIA3 TRIM58 OBSCN VWA7 C16orf46 WDR6 GIGYF2

1.21e-07166103732d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellcritical-Epithelial-Squamous|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CRYBG2 TMPRSS11E PRSS22 TMPRSS11F ABHD5 TMPRSS11D TMPRSS2

3.85e-071971037cfbdaada7169afb68455724ae87032ff311b2d89
ToppCellNS-control-d_0-4-Epithelial-Squamous|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11F ABHD5 TMPRSS11D TMPRSS2

3.85e-071971037ab965a0ba87efd3329d24a1ec123985f46fc17c0
ToppCellmoderate-Epithelial-Squamous|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CRYBG2 TMPRSS11E PRSS22 TMPRSS11F ABHD5 TMPRSS11D TMPRSS2

3.85e-071971037ab3c90a5b643b45d0b83939c6304b11f567c5d78
ToppCellNS-moderate-d_07-13-Epithelial-Squamous|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11F ABHD5 TMPRSS11D TMPRSS2

3.99e-071981037b7495369baba203490c067a58fc8456a778a12e4
ToppCellP03-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTSL1 HAPLN4 GAS7 TMPRSS5 DLL3 CLDN19

4.44e-0618410368880ff36c243cc60a524d74934d000aef26a70ac
ToppCell(5)_Epi_upper|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

TMPRSS11E PRSS22 SLC16A3 TMPRSS11D TMPRSS2 DTX2

5.66e-0619210360c8f73cfd24531a040544df39f28626433aaa651
ToppCell(5)_Epithelial_cells-(5)_Epi_upper|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

TMPRSS11E PRSS22 SLC16A3 TMPRSS11D TMPRSS2 DTX2

5.66e-06192103669b6b3ceaad6432c46d1bc2a00b8389069a8876e
ToppCellNS-moderate-d_16-33-Epithelial-Squamous|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11F TMPRSS11D TMPRSS2

5.66e-061921036103496f428f59683ac3ae6147682c07c30663724
ToppCellNS-critical-d_07-13-Epithelial-Squamous|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11F TMPRSS11D TMPRSS2

6.01e-06194103653a34843d529ef395deb27086f71f7049a087bab
ToppCellNS-critical-d_0-4-Epithelial-Squamous|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11F TMPRSS11D TMPRSS2

6.01e-061941036614d0c25b56957c70f397abb169fd2a860eb1c06
ToppCellcritical-Epithelial-Squamous|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CRYBG2 TMPRSS11E PRSS22 TMPRSS11F TMPRSS11D TMPRSS2

6.56e-061971036eccc80d6ab79c46b10108de1cff3abeacfc105cd
ToppCellmoderate-Epithelial-Squamous|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CRYBG2 TMPRSS11E PRSS22 ABHD5 TMPRSS11D TMPRSS2

6.56e-0619710362e13881f917d4f62a5b3e968e41c57e43300d988
ToppCellcontrol-Epithelial-Squamous|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CRYBG2 TMPRSS11E PRSS22 ABHD5 TMPRSS11D TMPRSS2

6.75e-0619810366ba669ac1ed275ae309054941b1457e315766faa
ToppCellcontrol-Epithelial-Squamous|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CRYBG2 TMPRSS11E PRSS22 ABHD5 TMPRSS11D TMPRSS2

6.95e-061991036e13dca7a055cdca53dd6c26c04b2a46d58b419b6
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Cplx3-Hs6st2_(Entorhinal_cortex)|Hippocampus / BrainAtlas - Mouse McCarroll V32

PRSS22 PTH2R TMPRSS7 SLC39A5

1.88e-0568103475e81b353ef313d5e98d5c98d584335f1d1fa658
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Cplx3-Hs6st2_(Entorhinal_cortex)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

PRSS22 PTH2R TMPRSS7 SLC39A5

1.88e-0568103401ba0ccc5732189a5c0c32cb7819289102711b93
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Htra1)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

PHETA2 TMPRSS2 CLDN19 GASK1A

2.00e-0569103454e5ede00ce2920158d1cc0ac8e718aa24a4342e
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Htra1)|Cerebellum / BrainAtlas - Mouse McCarroll V32

PHETA2 TMPRSS2 CLDN19 GASK1A

2.00e-05691034c93a47ee777b560f69b705d5d597f3cb3a3f558a
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Htra1)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

PHETA2 TMPRSS2 CLDN19 GASK1A

2.00e-056910348946d7e433c232c56563a6c464152c0a8cdbdf92
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|367C / Donor, Lineage, Cell class and subclass (all cells)

CRYBG2 SLC16A13 TMPRSS11E VARS1 EPHA4

2.51e-051491035f18bddc84b064f3d57a1281d5172c404d87f25da
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a6-Slc17a7-Slc17a8.Fezf2.Slc17a8_(Deep_layer_pyramidal_cells-Layer_5b)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TRIM58 TMPRSS11E PRSS42P SLC39A5

2.64e-05741034e6c8b8046948a205e996e585f983fd0af80d5491
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LDHAL6B PTH2R FREM1 APCDD1L SLC39A5

2.76e-051521035eee86b508b8f140ea44e21d8c04c409a7b689e39
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 RLN3 MAMDC4 ADAMTS14 TECPR1

3.43e-051591035d2de9391b00b6c47f5fe28a1bad6da2097107ee0
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 RLN3 MAMDC4 ADAMTS14 TECPR1

3.43e-051591035da6b7f8039adc19839d6c090a0b3d68fb6445a79
ToppCellfacs-Marrow-T_cells-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 LDHAL6B SRMS FGL2 GASK1A

5.12e-051731035e0cf99ddbe6e9eab05d7bf89e9aa124850c6a807
ToppCellfacs-Marrow-T_cells-18m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS6 LDHAL6B SRMS FGL2 GASK1A

5.41e-0517510354be01bf30331162f1998216fb2871a4e626dc440
ToppCellBAL-Control-cDC_11|Control / Compartment, Disease Groups and Clusters

CRYBG2 SLC16A9 ECE1 FGL2 DLL3

5.41e-051751035daf014e15a354956e9149c83fd89d0af0d07eb00
ToppCellP15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTSL1 DTX1 OSCAR FGL2 FCGRT

5.41e-05175103584d252f3e432231687613299bbea14978bb4b06b
ToppCellP15-Endothelial-lymphatic_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTSL1 DTX1 OSCAR FGL2 FCGRT

5.41e-051751035a00c6fa9b33640710dd05a3799031147196f0986
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-5|TCGA-Lung / Sample_Type by Project: Shred V9

CRYBG2 TMPRSS11F TMPRSS11D PEDS1 FAM181B

5.71e-051771035a0c7d08469c513cecf87777c19876884f1511570
ToppCellPSB-critical-LOC-Epithelial-Squamous|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

6.68e-0518310352cf798a2371c61322484ea16fdfae0acfa94f102
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRYBG2 TMPRSS11E PRSS22 TMPRSS11F TMPRSS11D

7.04e-051851035f3fbc3096f85397a959cee17c3c4fcf2d511f3d5
ToppCell3'_v3-blood-Hematopoietic_progenitors-Progenitor_Erythro-Mega|blood / Manually curated celltypes from each tissue

SLC16A9 TRIM58 ITGA2B FREM1 FAM181B

7.22e-05186103559c115bbbb4bca4ad80be1809d8a0422b8438ea3
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GAS7 TMPRSS5 FGL2 ADAMTS7 CLDN19

7.59e-051881035502045a39ffb1e92bd9499848368e8fa971edb88
ToppCellfacs-Marrow-KLS-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2B1 AMZ1 ECE1 FGL2 MOGS

7.78e-051891035b28a0e2d5a5f512f9b137b162b195bdc3d5ee9ba
ToppCellBL-critical-LOC-Epithelial-Squamous|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

8.18e-0519110353f9b8c4fb72ae6f3167b187e6715c4dcb3159f98
ToppCellCF-Epithelial|CF / Disease state, Lineage and Cell class

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

8.59e-051931035518901c2e36a79c6189cd0d9e6d36dbd4f56a79c
ToppCellCF-Epithelial-Epithelial_cell|CF / Disease state, Lineage and Cell class

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

8.59e-0519310354e3dda27c71b7fdac90d081f0d8e9ca3a8ea7820
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

OSCAR FGL2 ABHD5 SLC16A3 AP5B1

8.80e-051941035e2d0dfb92356fa7ad7008aa8ac4198e2ac5d2495
ToppCellCTRL-Epithelial-Epithelial_cell|CTRL / Disease state, Lineage and Cell class

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

8.80e-0519410352bc4deaf2a01a39809fc323962fce4286835209c
ToppCellCTRL-Epithelial|CTRL / Disease state, Lineage and Cell class

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

8.80e-05194103549dcb31427f370692308f939e23992925708abb7
ToppCellNS-moderate-d_07-13|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMPRSS11E PRSS22 TMPRSS11F CLEC17A TMPRSS11D

9.01e-051951035088209505a68519ec89f50f0576096da6966bf17
ToppCellNS-critical-d_16-33-Epithelial-Squamous|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

9.23e-05196103597e16d9833e4083d719ca7058d5fc9b11edb37e3
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TMPRSS6 RLN3 GAS7 FGL2 CLDN19

9.46e-051971035e2983ae16c72371fbf0e5c123de9f4d900724e5e
ToppCellCOVID-19_Moderate-Classical_Monocyte|COVID-19_Moderate / disease group, cell group and cell class

OSCAR GAS7 FGL2 FCGRT AP5B1

9.46e-05197103598d4107e457e7399a84439acd73bf8f59598971b
ToppCellCOVID-19_Moderate-Classical_Monocyte|World / disease group, cell group and cell class

OSCAR GAS7 FGL2 FCGRT AP5B1

9.46e-05197103516cf3939e700aef1e16159f0652ba2dfad287e7a
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

9.69e-051981035fb3965049cb1961de0d2e74370868e46aa5050c8
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

9.69e-05198103572d91bd0c727ecadc41e023a16c9326158db1b7b
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

9.69e-051981035441608034c787e55691558a480dcd07e37419138
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

9.69e-0519810359f5726aedd1fb132feab717a029fa302306461b5
ToppCellCOVID-19_Severe-Classical_Monocyte|COVID-19_Severe / disease group, cell group and cell class

OSCAR GAS7 FGL2 SLC16A3 FCGRT

9.69e-051981035b88c4c0ed1abf0a28dbe05b04b9bee1073855ba8
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

9.92e-0519910355a1557fe35aa48080d4967e8724bf27f9585a5fb
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

9.92e-0519910350a657475b92aa3a713da62da364525249fdc3886
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

9.92e-051991035a8f4bd0e65f36b29535864fae4347369d5c864d2
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

9.92e-051991035245b37df56dfbbdbac88f0e2fc3dfa0ed1abd588
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

9.92e-051991035eacea42e973f073b410f54c0a1b3a7f2dc2b5a29
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CRYBG2 TMPRSS11E PRSS22 TMPRSS11D TMPRSS2

9.92e-051991035dbb33f0e151b150ba9ca4612973f8034c62e762b
ToppCellcontrol-HLA-DR-_S100A+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

OSCAR GAS7 FGL2 SLC16A3 FCGRT

1.02e-042001035107a0665fb20247511a430178effd7630a619488
ToppCellCOVID-19-COVID-19_Severe-Myeloid|COVID-19_Severe / Disease, condition lineage and cell class

OSCAR GAS7 FGL2 SLC16A3 FCGRT

1.02e-0420010351315bc0582b19c2fed91c740a1a7e9285c700df1
ToppCellLA-04._Ventricular_Cardiomyocyte_I|LA / Chamber and Cluster_Paper

GPRASP1 ITGA2B TMPRSS11F DLL3

1.24e-04110103434dcd1e1e16e8b6088ff9a7a40532e8bd000c121
ToppCellLA-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

GPRASP1 ITGA2B TMPRSS11F DLL3

1.42e-041141034ca69dddbdc02fa5718c56362649cd4b9b54f94ce
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1|Hippocampus / BrainAtlas - Mouse McCarroll V32

TMPRSS6 SLC13A5 CLDN19 GASK1A

1.68e-04119103479342c491a214c870ff6215da613db4a28c9d587
ToppCellHippocampus-Macroglia-ASTROCYTE|Hippocampus / BrainAtlas - Mouse McCarroll V32

TMPRSS6 SLC13A5 CLDN19 GASK1A

1.68e-04119103436857095d4e4cc6428d13bf7de04daec1f4cde1e
ToppCellThalamus-Macroglia-ASTROCYTE|Thalamus / BrainAtlas - Mouse McCarroll V32

FREM1 ZC3H12D CLDN19 GASK1A

1.79e-041211034c3a4dfd19b7e8654e859df605d55155b530ad009
ToppCellThalamus-Macroglia-ASTROCYTE-Gja1|Thalamus / BrainAtlas - Mouse McCarroll V32

FREM1 ZC3H12D CLDN19 GASK1A

1.79e-041211034c3efd44bd01c12ef8c7ce4cc351af1540b70a63c
Diseaseinterferon alpha/beta receptor 1 measurement

ITSN1 TYK2

3.95e-049992EFO_0021850
DiseaseCongenital Disorders of Glycosylation

MOGS SLC35A2

4.93e-0410992C0282577
Diseasechronic kidney disease, Proteinuria

GAS7 SLC16A3

6.01e-0411992EFO_0003884, HP_0000093
DiseaseMetastatic melanoma

GUCY2D MAP3K10 EPHA4

8.03e-0454993C0278883
DiseaseNasal Cavity Polyp

MIA3 ITSN2 GIGYF2

8.47e-0455993EFO_1000391
Diseaserevision of total hip arthroplasty

VWA7 STRCP1

9.88e-0414992EFO_0020973
Diseaseintellectual disability (implicated_via_orthology)

ITSN1 ITGA2B ITSN2

2.08e-0375993DOID:1059 (implicated_via_orthology)
DiseaseICAM-1 measurement

TYK2 ICAM5

2.93e-0324992EFO_0004520
DiseaseMalignant neoplasm of breast

TMPRSS6 OBSCN LDHAL6B HAPLN4 MAMDC4 SLC16A3 JMJD6 ICAM5 ITSN2 SLC35A2

3.27e-0310749910C0006142

Protein segments in the cluster

PeptideGeneStartEntry
WGPGWQELAVTTGRI

MAMDC4

176

Q6UXC1
VGTWPSQEAGEPSVW

AMZ1

326

Q400G9
QGSLWTVLEPGGDWS

LINC00696

131

Q6ZRV3
WGAEGIPAPTCWIGT

CEP68

56

Q76N32
GLLGNSWGEGAPAWV

GSDMD

426

P57764
GGWWVSSGCEVRPAV

APCDD1L

281

Q8NCL9
GGWVGIIASTALPQW

CLDN19

16

Q8N6F1
TWREELGDQIGGPAW

DLL3

126

Q9NYJ7
EVGWVTAGLVIWAGT

ARMCX4

6

Q5H9R4
WPGGQASGVSWVGEE

ARMCX4

1246

Q5H9R4
GPGAEAVIGSWCWTE

ARMCX4

1736

Q5H9R4
RADVWELGTPEGQWV

ADAMTS14

1031

Q8WXS8
DVAELWTGGTVAWEP

ADAMTS7

1256

Q9UKP4
WTGGTVAWEPALEGG

ADAMTS7

1261

Q9UKP4
GPGSWDLQTVAVWGT

ADAMTS7

1321

Q9UKP4
GWEEAVQGWGRTSPA

C16orf46

66

Q6P387
VQQRGGPAWSGSLEW

NPFFR2

36

Q9Y5X5
AVWVLTGELWPGAEA

RLN3

11

Q8WXF3
EWWTGSIGDRSGIFP

ITSN2

1016

Q9NZM3
DPDWWQGEINGVTGL

ITSN2

1161

Q9NZM3
PLTWEHAWTGVPGGT

IQCE

96

Q6IPM2
WVWLNGGIGAPIVQD

PAQR3

221

Q6TCH7
SPDGGWGWVIVFVSF

SLC16A9

6

Q7RTY1
PGETVFVPGGWWHVV

JMJD6

261

Q6NYC1
EGWWTGQLPSGRVGV

MAP3K10

56

Q02779
PVLLAWGGVWSGEAH

PSMG3-AS1

36

Q96PY0
RVSWLGEEPVAGVWS

GRWD1

156

Q9BQ67
EEAGIALVPWGCPWT

GUCY2D

141

Q02846
TGVKAPDGGWGWAVL

SLC16A3

11

O15427
PAAVAVWEWQDGLGT

DTX2

16

Q86UW9
PGRGVVWEWLSDDGS

DTX2

106

Q86UW9
VGGSNAKEGAWPWVV

TMPRSS15

786

P98073
LAWPEEGPATAWSGE

HERC1

3531

Q15751
WISGWGSIQDGVPLP

PRSS22

176

Q9GZN4
GELGWIASPLEGGWE

EPHA4

41

P54764
QGGWPGELLASWEAQ

ADAMTSL1

1031

Q8N6G6
KQGTWGGDWPEALAI

FCGRT

146

P55899
VAGPWLWVAVGGAAG

ICAM5

831

Q9UMF0
GWILGEHGDSSVPVW

LDHAL6B

236

Q9BYZ2
SGAQEFGEPGWWKLV

KAT14

191

Q9H8E8
AESAIGWISSRPWVG

EBLN2

236

Q6P2I7
AGHWEWIGGEPVAFT

FREM1

2121

Q5H8C1
WGADTWGSVELPIVG

PEDS1

96

A5PLL7
LTDKVSPTGGGPWDW

AP5B1

211

Q2VPB7
SPTGGGPWDWTLVEE

AP5B1

216

Q2VPB7
GPWDWTLVEEGDGRL

AP5B1

221

Q2VPB7
SLWRSDGVWEGAPGE

FAM181B

406

A6NEQ2
SAPGKGIVWEWENDG

DTX1

101

Q86Y01
PGGQHGGDWSWRVTV

MOGS

176

Q13724
DWGPGVWSQPSDVLE

OSCAR

106

Q8IYS5
GAAWPGAGTGELLWD

OBSCN

6316

Q5VST9
TDGGARPVIWWAPDV

GASK1A

361

Q9UFP1
LIEKIGGWNITGPWD

EEF1AKMT4-ECE2

316

P0DPD8
WTLGTPAADVWILGT

FCAMR

371

Q8WWV6
PTVWEGGSVWDLPLD

GIGYF2

701

Q6Y7W6
GVSREDGPFWWAGLT

CPAMD8

651

Q8IZJ3
GEWVDESQTGEPGWL

ITSN1

771

Q15811
REVWGDIVDASGWAP

CRYBG2

1001

Q8N1P7
GLLCWPTAGSGEWVT

GHRHR

61

Q02643
VLAGWGLPVLFTGTW

GHRHR

246

Q02643
ELEWSVGPIPVGDTW

MAN2B1

711

O00754
VRNGIFWGTWPGVSE

FGL2

401

Q14314
GGGPSALWEITWERI

GBF1

1691

Q92538
DTERGVWEAWTGTPG

KLHDC9

111

Q8NEP7
AALGPGALWAAAWGV

HAPLN4

6

Q86UW8
ELIERLGGWNITGPW

ECE1

201

P42892
PGWPVGQEEWGVAHT

C1orf127

571

Q8N9H9
WESGLAEVWGAGVGP

HPS6

96

Q86YV9
GFMPGWLTVAWVEGE

SLC13A5

336

Q86YT5
AIGIPGWGFSGWISA

SCAMP3

251

O14828
WWVGDIPVSGALLTD

IZUMO4

41

Q1ZYL8
TEVPDGGWGWAVAVS

SLC16A6

16

O15403
EEEVIGPWFWSGEQV

GPRASP1

546

Q5JY77
GPWFWSGEQVDIEAG

GPRASP1

551

Q5JY77
EQGPGGLWVWGATAV

VARS1

61

P26640
LWGPEAEGGWTSREE

TADA2B

61

Q86TJ2
GWPEVWAGSVGRTFG

MIA3

81

Q5JRA6
GGGIWILAGITSWVA

OVCH1

246

Q7RTY7
LGSQAGPALGWRDTW

POMGNT1

196

Q8WZA1
GELITLLQVPDGGWW

GAS7

26

O60861
GLTWPVVLIWGNDAE

RNF43

156

Q68DV7
VGAPTWSWTLGAVEI

ITGA2B

286

P08514
FGEVWEGLWLGSLPV

SRMS

241

Q9H3Y6
GGQGAPWAEELLAGW

ROBO4

291

Q8WZ75
GLVGLWWAEGTAVAT

SLC35A2

246

P78381
WVVLGWVGGSVPNLG

SLC39A5

16

Q6ZMH5
GTESRDGPGWAQWLL

SREBF1

531

P36956
ADTGERSGWLTGWLP

ABHD5

11

Q8WTS1
EGDWRWLDGSPVTLS

CLEC17A

321

Q6ZS10
RILGGTEAEEGSWPW

TMPRSS11D

186

O60235
RIVGGTEVEEGEWPW

TMPRSS11E

191

Q9UL52
EWSVGLGTRPEEWGL

PRSS53

351

Q2L4Q9
TVRDAGSWWLAVPGA

STK19

281

P49842
RSAGWGLAEWELQGP

PHETA2

191

Q6ICB4
IVGGESALPGAWPWQ

TMPRSS2

256

O15393
GEWPWQASLQLIGSG

TMPRSS11F

216

Q6ZWK6
EPPDGGWGWVVVLSA

SLC16A13

6

Q7RTY0
GTPWCVVWTGDERVF

TCERG1

531

O14776
IIGGTDTLEGGWPWQ

TMPRSS7

606

Q7RTY8
DVDTWAISPRGAGWL

PPP6C

201

O00743
HPLWAWVSGGGCVVE

TECPR1

531

Q7Z6L1
LAEGGIRGLWAGWVP

SLC25A27

181

O95847
GVLWFVSVTTGPWGA

TM2D1

21

Q9BX74
CPDGDTWRLVGVVSW

TMPRSS5

411

Q9H3S3
VGGVDAEEGRWPWQV

PRSS42P

81

Q7Z5A4
VWLPWAEGSGCDGPV

PPP1R3F

616

Q6ZSY5
AWVITGGDDSGIRLW

WDR6

311

Q9NNW5
EWDGLICWPRGTVGK

PTH2R

66

P49190
VWAEPAWGDGATGGL

ZC3H12D

451

A2A288
VDWGVLSTLGQIDGW

STRCP1

1546

A6NGW2
EGTEGPTSTRPEWVW

nan

91

Q8N1Y9
AGSPWWGTVGGVLLL

VWA7

871

Q9Y334
GETTPSPENGVWALW

TRIM58

371

Q8NG06
RIVGGAVSSEGEWPW

TMPRSS6

576

Q8IU80
VLVTGTGGIQWWPVE

TYK2

316

P29597
WVPAIPQEGNTGDWE

ZNF641

81

Q96N77