Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrotubule minus-end binding

HAUS7 TUBGCP2 HAUS4 CAMSAP1

8.61e-06151834GO:0051011
GeneOntologyMolecularFunctioncalmodulin binding

TRPV1 RASGRF2 UBR4 OBSCN PHKA1 IQCB1 KCNQ1 CDK5RAP2 CAMSAP1 MYO15A UNC13A

9.35e-0623018311GO:0005516
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

RAPGEF6 GBF1 RASGRF2 KALRN DOCK8 SH2D3C OBSCN PLCD4 PLEKHG6 MCF2L

5.58e-0523118310GO:0005085
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RAPGEF6 GBF1 GARNL3 ARHGAP40 RASGRF2 KALRN DOCK8 SH2D3C OBSCN PLCD4 NF1 PLEKHG6 SGSM2 ARHGAP28 MCF2L

7.05e-0550718315GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RAPGEF6 GBF1 GARNL3 ARHGAP40 RASGRF2 KALRN DOCK8 SH2D3C OBSCN PLCD4 NF1 PLEKHG6 SGSM2 ARHGAP28 MCF2L

7.05e-0550718315GO:0030695
GeneOntologyMolecularFunctionanandamide 8,9 epoxidase activity

CYP2D7 CYP2D6

4.95e-0441832GO:0062187
GeneOntologyMolecularFunctionanandamide 11,12 epoxidase activity

CYP2D7 CYP2D6

4.95e-0441832GO:0062188
GeneOntologyMolecularFunctionsteroid 21-monooxygenase activity

CYP2D7 CYP2D6

4.95e-0441832GO:0004509
GeneOntologyMolecularFunctionprogesterone 21-hydroxylase activity

CYP2D7 CYP2D6

4.95e-0441832GO:0106309
GeneOntologyMolecularFunctionmicrotubule binding

HAUS7 CKAP5 TUBGCP2 CCDC88B LRPPRC HAUS4 NF1 NDC80 CDK5RAP2 CAMSAP1

5.70e-0430818310GO:0008017
GeneOntologyBiologicalProcessregulation of protein polymerization

MKKS HAUS7 ARHGAP40 CKAP5 RICTOR HAUS4 AKAP9 MTOR CDK5RAP2 ARHGAP28 CAMSAP1 BAIAP2L2

1.04e-0623118212GO:0032271
GeneOntologyBiologicalProcessprotein polymerization

MKKS HAUS7 ARHGAP40 CKAP5 RICTOR TUBGCP2 HAUS4 AKAP9 MTOR CDK5RAP2 ARHGAP28 CAMSAP1 BAIAP2L2

8.93e-0633418213GO:0051258
GeneOntologyBiologicalProcessregulation of microtubule polymerization

HAUS7 CKAP5 HAUS4 AKAP9 CDK5RAP2 CAMSAP1

3.29e-05691826GO:0031113
GeneOntologyBiologicalProcessorganelle assembly

ATG101 MKKS DNHD1 HAUS7 GBF1 CCDC146 OBSCN FASTKD2 TUBGCP2 CENPK HPS3 DNAAF3 HAUS4 CFAP54 CELSR2 NDC80 AP1G1 MTOR IQCB1 KCNQ1 CDK5RAP2 ODAD3 CFAP46 SMAD4

6.65e-05113818224GO:0070925
GeneOntologyBiologicalProcessmicrotubule polymerization

HAUS7 CKAP5 TUBGCP2 HAUS4 AKAP9 CDK5RAP2 CAMSAP1

8.13e-051171827GO:0046785
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

DOK6 RAPGEF6 GBF1 GARNL3 ARHGAP40 RASGRF2 KALRN DOCK8 SH2D3C OBSCN PLCD4 NF1 PLEKHG6 ARHGAP28 MCF2L

8.97e-0553818215GO:0007264
GeneOntologyCellularComponentcentrosome

MKKS RAD51D HAUS7 RAPGEF6 CCDC146 UBR4 CKAP5 TENT5C TUBGCP2 CCDC88B TRIM69 HAUS4 AKAP9 PLEKHG6 NDC80 IQCB1 CDK5RAP2 NUP93 ESPL1 SMAD4

1.58e-0577018420GO:0005813
GeneOntologyCellularComponentmicrotubule organizing center

MKKS RAD51D HAUS7 RAPGEF6 CCDC146 UBR4 CKAP5 TENT5C TUBGCP2 CCDC88B TRIM69 HAUS4 AKAP9 PLEKHG6 NDC80 IQCB1 CDK5RAP2 NUP93 CAMSAP1 ESPL1 ODAD3 SMAD4

2.05e-0591918422GO:0005815
GeneOntologyCellularComponentlaminin-1 complex

LAMA1 LAMB1

2.30e-0431842GO:0005606
DomainARM-type_fold

WAPL GBF1 DOCK8 NEK10 UBR4 VEPH1 CKAP5 RICTOR NBEA CTIF VIRMA URB1 NF1 AP1G1 MTOR MROH2B IQCB1 AP1G2 HEATR5B PPP6R2 GCN1 GPRASP2

2.02e-1233918122IPR016024
DomainARM-like

DOCK8 NEK10 CKAP5 RICTOR NBEA NF1 AP1G1 MTOR MROH2B IQCB1 AP1G2 HEATR5B PPP6R2 GCN1 GPRASP2

6.19e-0827018115IPR011989
Domain-

NEK10 CKAP5 RICTOR NF1 AP1G1 MTOR MROH2B AP1G2 HEATR5B GCN1

6.33e-05222181101.25.10.10
DomainPH_dom-like

DOK6 RASGRF2 KALRN VEPH1 OBSCN PLCD4 NBEA CMIP PLEKHG6 CADPS OSBPL10 FRMPD3 MCF2L FRMD5

7.28e-0542618114IPR011993
DomainPH

DOK6 RASGRF2 KALRN VEPH1 OBSCN PLCD4 CMIP PLEKHG6 CADPS OSBPL10 MCF2L

8.77e-0527818111SM00233
DomainPH_DOMAIN

DOK6 RASGRF2 KALRN VEPH1 OBSCN PLCD4 CMIP PLEKHG6 CADPS OSBPL10 MCF2L

9.06e-0527918111PS50003
DomainPPR_long

LRPPRC PTCD1

9.34e-0521812IPR033443
DomainPPR_long

LRPPRC PTCD1

9.34e-0521812PF17177
DomainAP1_complex_gsu

AP1G1 AP1G2

9.34e-0521812IPR017107
DomainPH_domain

DOK6 RASGRF2 KALRN VEPH1 OBSCN PLCD4 CMIP PLEKHG6 CADPS OSBPL10 MCF2L

9.35e-0528018111IPR001849
DomainDUF2075

SLFN13 SLFN11

2.78e-0431812PF09848
DomainPPR_3

LRPPRC PTCD1

2.78e-0431812PF13812
DomainDUF2075

SLFN13 SLFN11

2.78e-0431812IPR018647
Domain-

PRAMEF7 MXRA5 LRFN3 LRRC32 PRAMEF12 PRAMEF8 FBXL5 TLR10 CMIP LRRC75A GP5

3.07e-04321181113.80.10.10
DomainDH_1

RASGRF2 KALRN OBSCN PLEKHG6 MCF2L

3.61e-04631815PS00741
DomainL_dom-like

PRAMEF7 MXRA5 LRFN3 LRRC32 PRAMEF12 PRAMEF8 FBXL5 TLR10 CMIP LRRC75A GP5

3.68e-0432818111IPR032675
DomainPH

DOK6 RASGRF2 KALRN VEPH1 OBSCN PLCD4 CADPS OSBPL10 MCF2L

4.06e-042291819PF00169
DomainRhoGEF

RASGRF2 KALRN OBSCN PLEKHG6 MCF2L

5.15e-04681815SM00325
DomainPPR

LRPPRC PTCD1

5.53e-0441812PF01535
DomainDUF1693

TENT5A TENT5C

5.53e-0441812IPR012937
DomainDUF1693

TENT5A TENT5C

5.53e-0441812SM01153
DomainNTP_transf_7

TENT5A TENT5C

5.53e-0441812PF07984
DomainRhoGEF

RASGRF2 KALRN OBSCN PLEKHG6 MCF2L

5.88e-04701815PF00621
DomainHEAT_REPEAT

CKAP5 MTOR MROH2B HEATR5B GCN1

5.88e-04701815PS50077
DomainDH_2

RASGRF2 KALRN OBSCN PLEKHG6 MCF2L

5.88e-04701815PS50010
Domain-

RASGRF2 KALRN OBSCN PLEKHG6 MCF2L

6.28e-047118151.20.900.10
DomainDH-domain

RASGRF2 KALRN OBSCN PLEKHG6 MCF2L

6.28e-04711815IPR000219
DomainPRAME_family

PRAMEF7 PRAMEF12 PRAMEF8

7.74e-04191813IPR026271
DomainGAE

AP1G1 AP1G2

9.16e-0451812PS50180
DomainDUF1041

CADPS UNC13A

9.16e-0451812SM01145
Domain-

ST7L INTS8 LRPPRC CFAP54 TTC23 SH3TC1 MTOR CFAP46

9.47e-0420718181.25.40.10
DomainIQ

RASGRF2 OBSCN IQCB1 MYO18B MYO15A

1.14e-03811815SM00015
Domain-

AP1G1 AP1G2

1.37e-03618122.60.40.1230
DomainClathrin_g-adaptin_app

AP1G1 AP1G2

1.37e-0361812IPR008153
Domain-

DOK6 RASGRF2 KALRN VEPH1 OBSCN PLCD4 PLEKHG6 CADPS OSBPL10 MCF2L FRMD5

1.55e-03391181112.30.29.30
DomainSEC14

KALRN NF1 MCF2L

1.76e-03251813SM00516
DomainIQ_motif_EF-hand-BS

RASGRF2 OBSCN IQCB1 MYO18B MYO15A

1.83e-03901815IPR000048
DomainMunc13_1

CADPS UNC13A

1.90e-0371812IPR014770
DomainMHD1

CADPS UNC13A

1.90e-0371812PS51258
DomainAlbA_2

SLFN13 SLFN11

1.90e-0371812PF04326
DomainSchlafen

SLFN13 SLFN11

1.90e-0371812IPR029684
DomainSchlafen_AAA_dom

SLFN13 SLFN11

1.90e-0371812IPR007421
DomainDUF1041

CADPS UNC13A

1.90e-0371812PF06292
DomainCAPS_dom

CADPS UNC13A

1.90e-0371812IPR010439
DomainTPR-like_helical_dom

ST7L INTS8 LRPPRC CFAP54 TTC23 SH3TC1 MTOR CFAP46

2.00e-032331818IPR011990
DomainIQ

RASGRF2 OBSCN IQCB1 MYO18B MYO15A

2.11e-03931815PS50096
PathwayREACTOME_M_PHASE

HAUS7 H2AB1 H2AB2 WAPL CKAP5 TUBGCP2 CENPK HAUS4 AKAP9 NDC80 CDK5RAP2 NUP93 ESPL1

2.53e-0538712013MM15364
PathwayREACTOME_MITOTIC_PROMETAPHASE

HAUS7 WAPL CKAP5 TUBGCP2 CENPK HAUS4 AKAP9 NDC80 CDK5RAP2

5.65e-052021209MM15362
PathwayREACTOME_MITOTIC_PROMETAPHASE

HAUS7 WAPL CKAP5 TUBGCP2 CENPK HAUS4 AKAP9 NDC80 CDK5RAP2

6.10e-052041209M4217
PathwayREACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES

HAUS7 CKAP5 TUBGCP2 HAUS4 AKAP9 CDK5RAP2

6.47e-05811206M748
PathwayREACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES

HAUS7 CKAP5 TUBGCP2 HAUS4 AKAP9 CDK5RAP2

1.17e-04901206MM14979
PathwayREACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES

HAUS7 CKAP5 TUBGCP2 HAUS4 AKAP9 CDK5RAP2

1.57e-04951206M6729
PathwayREACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE

HAUS7 CKAP5 HAUS4 AKAP9 IQCB1 CDK5RAP2

1.67e-04961206MM15207
PathwayREACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE

HAUS7 CKAP5 HAUS4 AKAP9 IQCB1 CDK5RAP2

1.76e-04971206M27478
PathwayREACTOME_RHOA_GTPASE_CYCLE

ARHGAP40 RASGRF2 KALRN OBSCN PLEKHG6 ARHGAP28 MCF2L

2.09e-041421207MM15576
PathwayREACTOME_M_PHASE

HAUS7 H2AB1 WAPL CKAP5 TUBGCP2 CENPK HAUS4 AKAP9 NDC80 CDK5RAP2 NUP93 ESPL1

2.26e-0441712012M27662
PathwayREACTOME_RHOA_GTPASE_CYCLE

ARHGAP40 RASGRF2 KALRN OBSCN PLEKHG6 ARHGAP28 MCF2L

2.81e-041491207M41805
PathwayREACTOME_CILIUM_ASSEMBLY

MKKS HAUS7 GBF1 CKAP5 HAUS4 AKAP9 IQCB1 CDK5RAP2

3.19e-042011208M27472
PathwayREACTOME_AURKA_ACTIVATION_BY_TPX2

HAUS7 CKAP5 HAUS4 AKAP9 CDK5RAP2

3.42e-04711205MM15495
PathwayREACTOME_AURKA_ACTIVATION_BY_TPX2

HAUS7 CKAP5 HAUS4 AKAP9 CDK5RAP2

3.65e-04721205M27749
PathwayWP_SEROTONIN_AND_ANXIETY

TRPV1 PLCD4 CRH

3.75e-04171203M39511
PathwayWP_SEROTONIN_AND_ANXIETY

TRPV1 PLCD4 CRH

3.75e-04171203MM15861
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

RAPGEF6 GBF1 KALRN UBR4 HECTD4 OBSCN MED14 IPP GRID1 HAUS4 URB1 KMT2D CELSR2 SH3TC1 MTOR SGSM2 AP1G2 MAPKBP1 SYVN1 MCF2L CAMSAP1 ESPL1 GCN1

3.71e-0811051882335748872
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RAPGEF6 GBF1 CKAP5 RICTOR VIRMA E2F8 ZNF106 LRPPRC VPS13D NF1 AKAP9 MTOR DSTYK IQCB1 OSBPL10 NCOA7 NUP93 CAMSAP1 GOLGB1

2.56e-078611881936931259
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KALRN ZNF618 UBR4 HECTD4 CKAP5 NBEA CCDC177 VIRMA LRPPRC NF1 AKAP9 CELSR2 MTOR CDK5RAP2 FRMPD3 CAMSAP1 PPP6R2 UNC13A GOLGB1

1.36e-069631881928671696
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

PRPSAP2 PRAMEF7 AMFR GBF1 TENT5C PRAMEF12 PRAMEF8 VIRMA KCNH4 ZNF106 LRPPRC CMIP NF1 AKAP9 MTOR FBXO7 CDK5RAP2 TIMELESS MCF2L MYO15A RUNDC1

4.18e-0612421882130973865
Pubmed

Defining the membrane proteome of NK cells.

AMFR GBF1 MED16 DOCK8 UBR4 CKAP5 MED14 TUBGCP2 CCDC88B LRPPRC LMF2 NF1 NDC80 AP1G1 MTOR NUP93 SYVN1 HEATR5B GCN1 GOLGB1

5.97e-0611681882019946888
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

PRAMEF7 RAPGEF6 WAPL CYP27B1 OBSCN RICTOR PRAMEF12 PRAMEF8 E2F8 URB1 AP1G1 PTCD1 FBXO7 CDK5RAP2 TMEM131 TIMELESS MTO1 ESPL1 GOLGB1

7.45e-0610841881911544199
Pubmed

A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5).

AMFR CMIP NF1 AKAP9 RUNDC1

8.40e-0651188528185240
Pubmed

Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival.

RICTOR NF1 MTOR

1.27e-059188327340174
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

HAUS7 CKAP5 TUBGCP2 HAUS4 AKAP9 IQCB1 CDK5RAP2

1.55e-05146188721399614
Pubmed

Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.

PRAMEF7 PRAMEF12 PKD1L2 PRAMEF8

2.03e-0530188438786026
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

WAPL GNE UBR4 PHKA1 LRPPRC IQCB1 SHPRH PPP6R2

2.18e-05212188833853758
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

ATG101 GNE TCP11L1 CYP27B1 CKAP5 PLCD4 TNIP1 RICTOR ZC4H2 BIK TLR10 NF1 TTC23 MTOR FBXO28 EMG1 TIMELESS SLFN11 ESPL1 GOLGB1

2.58e-0512931882015342556
Pubmed

AP-1 clathrin adaptor and CG8538/Aftiphilin are involved in Notch signaling during eye development in Drosophila melanogaster.

AP1G1 AP1G2

2.91e-052188222389401
Pubmed

Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2.

RICTOR MTOR

2.91e-052188220501647
Pubmed

SMAD4 and NF1 mutations as potential biomarkers for poor prognosis to cetuximab-based therapy in Chinese metastatic colorectal cancer patients.

NF1 SMAD4

2.91e-052188229703253
Pubmed

Molecular evolution of the CYP2D subfamily in primates: purifying selection on substrate recognition sites without the frequent or long-tract gene conversion.

CYP2D7 CYP2D6

2.91e-052188225808902
Pubmed

Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?

CYP2D7 CYP2D6

2.91e-052188211207030
Pubmed

Mutation of an A-kinase-anchoring protein causes long-QT syndrome.

AKAP9 KCNQ1

2.91e-052188218093912
Pubmed

Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism.

RICTOR MTOR

2.91e-052188220332342
Pubmed

mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue.

RICTOR MTOR

2.91e-052188226772600
Pubmed

Involvement of Rictor/mTORC2 in cardiomyocyte differentiation of mouse embryonic stem cells in vitro.

RICTOR MTOR

2.91e-052188228123351
Pubmed

A carbazole alkaloid deactivates mTOR through the suppression of rictor and that induces apoptosis in lung cancer cells.

RICTOR MTOR

2.91e-052188225893736
Pubmed

TENT5 cytoplasmic noncanonical poly(A) polymerases regulate the innate immune response in animals.

TENT5A TENT5C

2.91e-052188236383655
Pubmed

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism.

CYP2D7 CYP2D6

2.91e-05218823123997
Pubmed

A new link between transcriptional initiation and pre-mRNA splicing: The RNA binding histone variant H2A.B.

H2AB1 H2AB2

2.91e-052188228234895
Pubmed

Targeting mTORC2 inhibits colon cancer cell proliferation in vitro and tumor formation in vivo.

RICTOR MTOR

2.91e-052188220226010
Pubmed

Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors.

RICTOR MTOR

2.91e-052188225740823
Pubmed

A mutation in the cardiac KV7.1 channel possibly disrupts interaction with Yotiao protein.

AKAP9 KCNQ1

2.91e-052188238657442
Pubmed

MTOR signaling is essential for the development of thymic epithelial cells and the induction of central immune tolerance.

RICTOR MTOR

2.91e-052188229099279
Pubmed

mTORC2 regulates auditory hair cell structure and function.

RICTOR MYO15A

2.91e-052188237694145
Pubmed

Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance.

RICTOR MTOR

2.91e-052188226170313
Pubmed

Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia.

RICTOR MTOR

2.91e-052188222473959
Pubmed

Laminin terminates the Netrin/DCC mediated attraction of vagal sensory axons.

LAMA1 LAMB1

2.91e-052188218418846
Pubmed

Gene editing of the multi-copy H2A.B gene and its importance for fertility.

H2AB1 H2AB2

2.91e-052188230704500
Pubmed

Histone variants at the transcription start-site.

H2AB1 H2AB2

2.91e-052188224768041
Pubmed

H2A.Bbd: an X-chromosome-encoded histone involved in mammalian spermiogenesis.

H2AB1 H2AB2

2.91e-052188220008104
Pubmed

TOR complex 2 is needed for cell cycle progression and anchorage-independent growth of MCF7 and PC3 tumor cells.

RICTOR MTOR

2.91e-052188218831768
Pubmed

Monoclonal anti-mouse laminin antibodies: AL-1 reacts with laminin alpha1 chain, AL-2 with laminin beta1 chain, and AL-4 with the coiled-coil domain of laminin beta1 chain.

LAMA1 LAMB1

2.91e-052188216631359
Pubmed

Characterization of Cyp2d22, a novel cytochrome P450 expressed in mouse mammary cells.

CYP2D7 CYP2D6

2.91e-052188211032406
Pubmed

MYO18B promotes hepatocellular carcinoma progression by activating PI3K/AKT/mTOR signaling pathway.

MTOR MYO18B

2.91e-052188230390677
Pubmed

Rapamycin attenuates endothelial apoptosis induced by low shear stress via mTOR and sestrin1 related redox regulation.

SESN1 MTOR

2.91e-052188224587596
Pubmed

Hyperactivation of mTOR critically regulates abnormal osteoclastogenesis in neurofibromatosis Type 1.

NF1 MTOR

2.91e-052188221748792
Pubmed

Phosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channel.

AKAP9 KCNQ1

2.91e-052188216002409
Pubmed

Adipocyte-specific mTORC2 deficiency impairs BAT and iWAT thermogenic capacity without affecting glucose uptake and energy expenditure in cold-acclimated mice.

RICTOR MTOR

2.91e-052188234541875
Pubmed

The amino acid metabolite homocysteine activates mTORC1 to inhibit autophagy and form abnormal proteins in human neurons and mice.

CBS MTOR

2.91e-052188228148781
Pubmed

Form and function: the laminin family of heterotrimers.

LAMA1 LAMB1

2.91e-052188210842354
Pubmed

Histone variant selectivity at the transcription start site: H2A.Z or H2A.Lap1.

H2AB1 H2AB2

2.91e-052188224213378
Pubmed

Distinct roles of the mTOR components Rictor and Raptor in MO7e megakaryocytic cells.

RICTOR MTOR

2.91e-052188219341427
Pubmed

Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways.

RICTOR MTOR

2.91e-052188220620941
Pubmed

The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection.

CYP2D7 CYP2D6

2.91e-052188219594327
Pubmed

Coding-noncoding gene expression in intrahepatic cholangiocarcinoma.

CYP2D7 CYP2D6

2.91e-052188226297049
Pubmed

Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11 during the replication stress response.

SLFN13 SLFN11

2.91e-052188237833372
Pubmed

Targeting of gp78 for ubiquitin-mediated proteasomal degradation by Hrd1: cross-talk between E3s in the endoplasmic reticulum.

AMFR SYVN1

2.91e-052188219835843
Pubmed

Mammalian target of rapamycin complex 2 (mTORC2) coordinates pulmonary artery smooth muscle cell metabolism, proliferation, and survival in pulmonary arterial hypertension.

RICTOR MTOR

2.91e-052188224270265
Pubmed

A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine.

CYP2D7 CYP2D6

2.91e-052188215051713
Pubmed

Cytoplasmic polyadenylation by TENT5A is required for proper bone formation.

TENT5A TENT5C

2.91e-052188233882302
Pubmed

mTOR complex 2 in adipose tissue negatively controls whole-body growth.

RICTOR MTOR

2.91e-052188219497867
Pubmed

chTOG is a conserved mitotic error correction factor.

CKAP5 NDC80

2.91e-052188233377866
Pubmed

Activation of mTORC2 by association with the ribosome.

RICTOR MTOR

2.91e-052188221376236
Pubmed

A TOG Protein Confers Tension Sensitivity to Kinetochore-Microtubule Attachments.

CKAP5 NDC80

2.91e-052188227156448
Pubmed

Rictor/mTORC2 pathway in oocytes regulates folliculogenesis, and its inactivation causes premature ovarian failure.

RICTOR MTOR

2.91e-052188225564616
Pubmed

Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.

SLFN13 SLFN11

2.91e-052188229563550
Pubmed

VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

AMFR WAPL GBF1 UBR4 NBEA TUBGCP2 MTOR IQCB1 ESPL1

2.96e-05288188923383273
Pubmed

ULK1 inhibits the kinase activity of mTORC1 and cell proliferation.

ATG101 RICTOR MTOR

4.27e-0513188321795849
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

GBF1 KALRN UBR4 OBSCN CKAP5 PHKA1 LRPPRC AP1G1 MTOR

4.50e-05304188932235678
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

GBF1 RICTOR LRPPRC MTOR NUP93 GCN1

5.05e-05120188627320910
Pubmed

Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.

RASGRF2 KALRN OBSCN MCF2L

5.29e-0538188411756498
Pubmed

Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients.

CCDC146 MTOR WDR87

5.42e-0514188328878358
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

AMFR WAPL UBR4 TUBGCP2 INTS8 LRPPRC URB1 LMF2 AP1G1 MTOR TIMELESS NUP93 HEATR5B ESPL1 GCN1 GPRASP2

5.84e-059421881631073040
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

HAUS7 WAPL TCP11L1 U2SURP CKAP5 LAMB1 TUBGCP2 ZNF106 TRIM69 HAUS4 URB1 NDC80 FBXO28 CDK5RAP2 TIMELESS NUP93 ESPL1 GCN1

6.06e-0511551881820360068
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

PRAMEF7 AMFR OBSCN MED14 PRAMEF12 PRAMEF8 VPS13D IQCB1 NUP93 MYO15A GCN1 GOLGB1

6.34e-055641881221565611
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

DHX36 GBF1 TUBGCP2 PHKA1 NDC80 NCOA7 CDK5RAP2 CAMSAP1

7.18e-05251188829778605
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

U2SURP CKAP5 VPS13D CADPS CDK5RAP2 UNC13A

7.88e-05130188612421765
Pubmed

Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.

AMFR UBR4 CKAP5 TUBGCP2 LRPPRC URB1 NF1 IQCB1 NUP93 GCN1

8.28e-054081881033766124
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

GBF1 ZNF618 TNIP1 RICTOR CTIF VPS13D CMIP PTCD1 DSTYK ARHGAP28 PPP6R2

8.46e-054931881115368895
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

HAUS7 WAPL DOCK8 U2SURP CKAP5 TUBGCP2 INTS8 NF1 NDC80 NUP93 GCN1 GOLGB1

8.52e-055821881220467437
Pubmed

Developmental loss of laminin from the interstitial extracellular matrix correlates with decreased laminin gene expression.

LAMA1 LAMB1

8.69e-05318822100263
Pubmed

Distribution and association of mTOR with its cofactors, raptor and rictor, in cumulus cells and oocytes during meiotic maturation in mice.

RICTOR MTOR

8.69e-053188223440873
Pubmed

mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition.

RICTOR MTOR

8.69e-053188225385646
Pubmed

Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan.

RICTOR MTOR

8.69e-053188225059582
Pubmed

Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.

VPS13D OSBPL10

8.69e-053188220610895
Pubmed

mTOR has a developmental stage-specific role in mitochondrial fitness independent of conventional mTORC1 and mTORC2 and the kinase activity.

RICTOR MTOR

8.69e-053188228813526
Pubmed

A590T mutation in KCNQ1 C-terminal helix D decreases IKs channel trafficking and function but not Yotiao interaction.

AKAP9 KCNQ1

8.69e-053188224713462
Pubmed

Differential distribution of laminin chains in the development and sex differentiation of mouse internal genitalia.

LAMA1 LAMB1

8.69e-05318827669546
Pubmed

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

RICTOR MTOR

8.69e-053188221358638
Pubmed

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.

RICTOR MTOR

8.69e-053188220008564
Pubmed

Epithelial-mesenchymal reprogramming by KLF4-regulated Rictor expression contributes to metastasis of non-small cell lung cancer cells.

RICTOR MTOR

8.69e-053188235982899
Pubmed

Association of 4p14 TLR locus with antibodies to Helicobacter pylori.

FAM114A1 TLR10

8.69e-053188226312625
Pubmed

Malignant hematopoietic cells induce an increased expression of VEGFR-1 and VEGFR-3 on bone marrow endothelial cells via AKT and mTOR signalling pathways.

FLT4 MTOR

8.69e-053188216959214
Pubmed

Differential expression of laminin A and B chains during development of embryonic mouse organs.

LAMA1 LAMB1

8.69e-05318822088723
Pubmed

Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex.

RICTOR MTOR

8.69e-053188223049074
Pubmed

Basal mTORC2 activity and expression of its components display diurnal variation in mouse perivascular adipose tissue.

RICTOR MTOR

8.69e-053188227016480
Pubmed

mTOR complex-2 activates ENaC by phosphorylating SGK1.

RICTOR MTOR

8.69e-053188220338997
Pubmed

Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells.

LAMA1 LAMB1

8.69e-05318821292752
Pubmed

TELO2 induced progression of colorectal cancer by binding with RICTOR through mTORC2.

RICTOR MTOR

8.69e-053188233416177
Pubmed

BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.

MTOR BAIAP2L2

8.69e-053188232570120
Pubmed

MicroRNA-let-7a regulates cell autophagy by targeting Rictor in gastric cancer cell lines MGC-803 and SGC-7901.

RICTOR MTOR

8.69e-053188229328491
Pubmed

mTOR phosphorylated at S2448 binds to raptor and rictor.

RICTOR MTOR

8.69e-053188219145465
Pubmed

The C-terminal region of A-kinase anchor protein 350 (AKAP350A) enables formation of microtubule-nucleation centers and interacts with pericentriolar proteins.

AKAP9 CDK5RAP2

8.69e-053188229054927
Pubmed

Morin Acts as a USP7 Inhibitor to Hold Back the Migration of Rheumatoid Arthritis Fibroblast-Like Synoviocytes in a "Prickle1-mTORC2" Dependent Manner.

RICTOR MTOR

8.69e-053188234331380
InteractionZNF252P-AS1 interactions

HPS3 AKAP9 CELSR2 AP5B1 FBXO7

3.60e-06271795int:ZNF252P-AS1
InteractionDUSP16 interactions

HAUS7 RAPGEF6 TNIP1 RICTOR VIRMA HPS3 HAUS4 IQCB1 CDK5RAP2 ESPL1 RUNDC1

9.23e-0623717911int:DUSP16
InteractionDCTN1 interactions

HAUS7 TRPV1 GBF1 CKAP5 MED14 TNIP1 RICTOR CTIF VIRMA FBXL5 HAUS4 NF1 NDC80 DSTYK CAMSAP1 ESPL1

9.78e-0649717916int:DCTN1
InteractionKRT8 interactions

HAUS7 RAPGEF6 UBR4 TNIP1 RICTOR VIRMA HAUS4 AKAP9 NDC80 IQCB1 CDK5RAP2 NUP93 SYVN1 CAMSAP1 PPP6R2

9.82e-0644117915int:KRT8
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOK6 RASGRF2 VEPH1 PLEKHG6 CADPS OSBPL10 MCF2L

3.68e-042061167682
GeneFamilyMTOR complex 1|MTOR complex 2

RICTOR MTOR

4.03e-04511621333
GeneFamilyPRAME family

PRAMEF7 PRAMEF12 PRAMEF8

4.72e-04241163686
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

FLT4 MXRA5 KALRN LRFN3 OBSCN IGSF9

6.02e-041611166593
GeneFamilySchlafen family

SLFN13 SLFN11

8.39e-04711621110
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RASGRF2 KALRN OBSCN MCF2L

8.53e-04661164722
GeneFamilyHAUS augmin like complex

HAUS7 HAUS4

1.11e-0381162581
GeneFamilyLaminin subunits

LAMA1 LAMB1

2.58e-03121162626
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

FRMPD3 MYO15A FRMD5

4.05e-035011631293
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_2|368C / Donor, Lineage, Cell class and subclass (all cells)

RAPGEF6 SH2D3C TENT5C CCDC88B CENPK BIK PCED1B ZNF599 KCNQ1 RUNDC1

4.75e-0918018610551b8de8d933d11bcd3897aeb2fd033355f958e2
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE KALRN LAMA1 OBSCN GRID1 ADGRV1 PKD1L2 MYO15A

1.10e-0618418682cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE KALRN LAMA1 OBSCN GRID1 ADGRV1 PKD1L2 MYO15A

1.10e-061841868ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE KALRN LAMA1 OBSCN GRID1 ADGRV1 PKD1L2 MYO15A

1.10e-0618418682b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC146 NEK10 NBEA CFAP54 SLFN13 PRR29 SHOC1 CFAP46

1.64e-0619418684a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_3|356C / Donor, Lineage, Cell class and subclass (all cells)

GNE TENT5C ZNF599 TRIM69 R3HDM4 MTOR KCNQ1

1.05e-051791867f378307eb20f002450c748b7be2289d6db2fcbcb
ToppCelldroplet-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 RASGRF2 LRRC32 SH2D3C PPP1R16B TIMELESS MCF2L

1.26e-051841867fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCelldroplet-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT4 RASGRF2 LRRC32 SH2D3C PPP1R16B TIMELESS MCF2L

1.26e-051841867ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCelldroplet-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 RASGRF2 LRRC32 SH2D3C PPP1R16B TIMELESS MCF2L

1.26e-0518418671d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCelldroplet-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 RASGRF2 LRRC32 SH2D3C PPP1R16B TIMELESS MCF2L

1.26e-05184186776caad53d55fff5acca27bf190a6de7b27437d9f
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT4 RASGRF2 LRRC32 SH2D3C PPP1R16B TIMELESS MCF2L

1.26e-0518418671fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT4 RASGRF2 LRRC32 SH2D3C PPP1R16B TIMELESS MCF2L

1.26e-0518418672467207aaea307873ab286f89cfc7668a227a694
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CCDC146 NEK10 DNAAF3 CFAP54 SLFN13 PRR29 CFAP46

1.30e-051851867f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CKAP5 CENPK E2F8 NDC80 SLFN13 CDK5RAP2 ESPL1

1.30e-05185186730e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT4 RASGRF2 LRRC32 SH2D3C PPP1R16B TIMELESS MCF2L

1.49e-05189186728b9e96a5206b7fdae9b17daf05c8f5d24b6c5ec
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

CCDC146 NEK10 DNAAF3 CFAP54 SLFN13 PRR29 CFAP46

1.55e-0519018677031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

CCDC146 NEK10 DNAAF3 CFAP54 SLFN13 PRR29 CFAP46

1.55e-051901867426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN LRRC32 SH2D3C PTGIS PCED1B PPP1R16B

1.60e-051911867f663131a4810584c5854bd64ee7991a237b7707f
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLT4 RASGRF2 KALRN LRRC32 PPP1R16B NCOA7 MCF2L

1.60e-0519118672f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 RASGRF2 KALRN LRRC32 SH2D3C PCED1B PPP1R16B

1.65e-051921867c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF2 KALRN KCNH4 KIAA1549L CELSR2 SGSM2 UNC13A

1.71e-051931867be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF2 KALRN KCNH4 KIAA1549L CELSR2 SGSM2 UNC13A

1.71e-0519318670c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF2 KALRN KCNH4 KIAA1549L CELSR2 SGSM2 UNC13A

1.71e-0519318678689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 RASGRF2 KALRN LRRC32 SH2D3C PCED1B PPP1R16B

1.71e-05193186752e918884877b6659cdca0496390e440f73694a9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN LRRC32 SH2D3C PTGIS PCED1B PPP1R16B

1.77e-051941867b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 KALRN LRRC32 SH2D3C PTGIS PCED1B PPP1R16B

1.77e-051941867fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 RASGRF2 KALRN LRRC32 SH2D3C PCED1B PPP1R16B

1.77e-051941867e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

FLT4 RASGRF2 KALRN LRRC32 SH2D3C PPP1R16B MCF2L

1.83e-051951867fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 RASGRF2 KALRN LRRC32 SH2D3C PCED1B PPP1R16B

1.89e-051961867023312af38f816a44b407e0daa32590d953caf99
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 RASGRF2 KALRN LRRC32 SH2D3C PCED1B PPP1R16B

1.89e-051961867ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

FLT4 RASGRF2 KALRN LRRC32 SH2D3C PPP1R16B MCF2L

1.89e-051961867b71b197cb92117dd9efaa13de000841901cc4ca8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 RASGRF2 KALRN LRRC32 SH2D3C PCED1B PPP1R16B

1.95e-051971867cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

FLT4 RASGRF2 KALRN LRRC32 SH2D3C PPP1R16B MCF2L

1.95e-051971867ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 RASGRF2 KALRN LRRC32 SH2D3C PCED1B PPP1R16B

1.95e-051971867412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC146 NEK10 DNAAF3 CFAP54 SLFN13 PRR29 CFAP46

2.02e-051981867ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 RASGRF2 KALRN LRRC32 SH2D3C PCED1B PPP1R16B

2.02e-0519818670a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOK6 HAUS7 GARNL3 KALRN CBS KCNH4 WDR87

2.08e-051991867b768496381362f9a2706e0892b5a7a0db82e09ce
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEK10 CYP27B1 LAMA1 GRID1 CELSR2 MYO15A

2.84e-0514118664aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEK10 CYP27B1 LAMA1 GRID1 CELSR2 MYO15A

2.84e-051411866e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEK10 CYP27B1 LAMA1 GRID1 CELSR2 MYO15A

2.96e-051421866759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC146 NEK10 CFAP54 PRR29 ODAD3 CFAP46

4.66e-0515418664e3bc24043144143842627cacf6f90dda2228910
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC146 NEK10 CFAP54 PRR29 ODAD3 CFAP46

4.66e-0515418667556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellCOVID-19-Myeloid-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

DOCK8 OR9G4 TLR10 SH3TC1 OR13A1 CCL17

5.00e-051561866a07a9096799e4ba663841c70035b4b32c1fda4f9
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KMT2D NDC80 EMG1 TIMELESS ESPL1 GPRASP2

6.61e-0516418664307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KMT2D NDC80 EMG1 TIMELESS ESPL1 GPRASP2

6.61e-0516418661d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CCDC146 TENT5A PTCD1 MTOR CAMSAP1 PDCD1LG2

6.61e-051641866d2218d50e0e2d19f919dcb460b3840687c082810
ToppCelldroplet-Heart-nan-24m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT4 TENT5C E2F8 CELSR2 ARHGAP28 RUNDC1

7.30e-051671866bad33497ceeab968a7eb8a48b921c6f936390743
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TCP11L1 CCDC88B HAUS4 NDC80 CCL17 SYVN1

7.55e-0516818664c402a1613fcf0a6e4d9b9d5551812940e91ff32
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

OBSCN VIRMA PRR29 ABCD4 HEATR5B SMAD4

7.55e-0516818668697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

RAD51D GBF1 NDC80 SGSM2 MCF2L MYO15A

7.55e-051681866ca94b29c1030484143a77f2df06dad74d2c6136e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC146 NEK10 NBEA CFAP54 PRR29 CFAP46

7.80e-05169186614aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEK10 CTIF SGSM2 PRR29 ODAD3 GP5

8.32e-0517118661854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCelldroplet-Kidney-KIDNEY-1m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM114A1 DOCK8 TENT5A ZBTB12 IGSF9 ESPL1

8.32e-051711866d9ad6a3bce3556abd24af1630bf4a99594437c3a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ARHGAP40 LAMA1 LAMB1 CFAP54 OSBPL10

8.59e-0517218660c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE ARHGAP40 LAMA1 LAMB1 CFAP54 OSBPL10

8.59e-051721866eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CKAP5 CENPK E2F8 NDC80 OSBPL10 CDK5RAP2

8.59e-0517218662b6cd84c946b1e800caba452ae70145ea285fec1
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel|Adult / Lineage, Cell type, age group and donor

KALRN SH2D3C CADPS OR13A1 PPP1R16B MCF2L

8.59e-051721866ad4ffdb3fc0c560a9cbaa2bc048476cbc43e8fd6
ToppCelldroplet-Lung-nan-21m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCP11L1 CENPK E2F8 DNAAF3 NDC80 CCL17

8.87e-0517318662eb6e9fc3a3654f6f86fbd112e80a18814afd103
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CENPK E2F8 NDC80 SLFN13 TIMELESS ESPL1

8.87e-051731866a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPK HAUS4 LMF2 NF1 NDC80 ESPL1

9.16e-05174186672df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPK HAUS4 LMF2 NF1 NDC80 ESPL1

9.16e-051741866c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCP11L1 CENPK E2F8 DNAAF3 NDC80 CCL17

9.45e-05175186673f25bd54309aed1480ddc44bdab518b17e71f92
ToppCelldroplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHKA1 NCOA7 IGSF9 PLA2G4F CCL17 PDCD1LG2

9.75e-05176186624b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGAP40 CCDC146 TENT5A NBEA ADGRV1 FRMD5

9.75e-0517618663bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN KCNH4 FRMPD3 MYO18B FRMD5 CFAP46

1.01e-041771866692cd03bf0958ebeec34d41bfe87713a768e9a8e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PHKA1 NCOA7 IGSF9 PLA2G4F CCL17 PDCD1LG2

1.01e-041771866f360f7099570d248531897b96e0de282e58f59e9
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN KCNH4 FRMPD3 MYO18B FRMD5 CFAP46

1.01e-041771866c08583ea68bbeb6b5de852a46b0c0f04792dae55
ToppCellFetal_29-31_weeks-Immune-dendritic_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK8 CCDC88B TLR10 SH3TC1 PPP1R16B CCL17

1.01e-041771866c5e829bc4594761666d65cace5a9c5d19c16f187
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NBEA ADGRV1 URB1 SGSM2 MCF2L GOLGB1

1.07e-0417918666e965e424eebef50f0202cff75f458be395cfca1
ToppCellCOVID-19-kidney-Stressed_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLT4 KALRN LRRC32 PPP1R16B NCOA7 MCF2L

1.07e-041791866754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CKAP5 CENPK E2F8 NDC80 CDK5RAP2 ESPL1

1.07e-04179186654191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCellCOVID-19-kidney-PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLT4 RASGRF2 KALRN LRRC32 PPP1R16B MCF2L

1.10e-041801866493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CENPK E2F8 NDC80 SLFN13 ESPL1 FRMD5

1.10e-041801866f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellControl-Myeloid-DC1|Control / Condition, Lineage and Cell class

GARNL3 ZBTB12 SLC30A4 BIK TLR10 SLFN13

1.14e-0418118665a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CKAP5 CENPK E2F8 NDC80 IGSF9 ESPL1

1.17e-041821866336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A|E18.5-samps / Age Group, Lineage, Cell class and subclass

SH2D3C E2F8 NDC80 PPP1R16B MCF2L ESPL1

1.17e-041821866ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT4 RASGRF2 SH2D3C FAM217A SH3TC1 PPP1R16B

1.17e-041821866d22ab50b135482915687c70e6dad29bfe2bb2c68
ToppCellmetastatic_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ|metastatic_Lymph_Node / Location, Cell class and cell subclass

PRPSAP2 BIK TLR10 SH3TC1 SYVN1 SERPINA9

1.21e-04183186630db83f600e2c4ad3af68a8a946673f4352a2807
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 RASGRF2 LRRC32 SH2D3C PCED1B PPP1R16B

1.24e-041841866688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

WAPL GBF1 TENT5A CKAP5 ABCD4 OSBPL10

1.24e-041841866ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCellCOPD-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

TRHDE AMFR DOCK8 LAMB1 TIMELESS HEATR5B

1.24e-0418418667fd0b227c3750ffb80e41e92c60fcce46656be14
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC146 CFAP54 PRR29 ODAD3 SERPINA9 CFAP46

1.24e-041841866797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC146 CFAP54 PRR29 ODAD3 SERPINA9 CFAP46

1.24e-04184186677d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCellCiliated_cells-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

CCDC146 NEK10 DNAAF3 CFAP54 PRR29 CFAP46

1.28e-0418518664fc7113d3dadc716ec5a8e62b58543cc00ce5b16
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

NEK10 CFAP54 SLFN13 PRR29 ODAD3 CFAP46

1.28e-04185186630f4980dee6cd5959655f8d74049f3bfb5312611
ToppCelldroplet-Bladder-BLADDER-1m-Hematologic-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH2D3C SH3TC1 PPP1R16B CDK5RAP2 IGSF9 TIMELESS

1.28e-041851866969248b63d4ce335f223528de756bcddffadbd77
ToppCellCOVID-CD4-CD8_1|COVID / Condition, Cell_class and T cell subcluster

RASGRF2 MED14 PCED1B ZNF599 NDC80 AP5B1

1.28e-041851866c634bb04a081ae3214b68f6e4a147db5b2b916ed
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

CCDC146 NEK10 DNAAF3 CFAP54 PRR29 CFAP46

1.32e-041861866f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

DOK6 RASGRF2 HECTD4 CMIP KCNQ1 PPP6R2

1.32e-041861866de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE DOCK8 LAMB1 CFAP54 OSBPL10 IGSF9

1.32e-0418618665c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellDividing_Macrophages-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CKAP5 CENPK E2F8 NDC80 SLC22A10 ESPL1

1.32e-0418618660067eb78d4c7e32b9563550d9fcaf13445ee6a48
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

DOK6 RASGRF2 HECTD4 CMIP KCNQ1 PPP6R2

1.32e-0418618660b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

WAPL MED14 VPS13D FBXO28 TMEM131 GP5

1.32e-04186186603db813598b67b1e08f759758a1c2023396921fa
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CCDC146 NEK10 DNAAF3 CFAP54 PRR29 CFAP46

1.36e-0418718662b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GNE ZNF599 TRIM69 R3HDM4 MTOR KCNQ1

1.36e-041871866c8278525b3e1d3f3f4defcaf109cce22dd2e157a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT4 RASGRF2 KALRN LRRC32 SH2D3C PCED1B

1.36e-04187186635c382c0aabd46906113e5db30ea24bb8e658899
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CENPK E2F8 NDC80 SLFN13 CDK5RAP2 ESPL1

1.36e-0418718669351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CKAP5 CCDC88B CENPK E2F8 NDC80 ESPL1

1.36e-04187186673931a5ea73799095daff100b5f18853c57c74dc
ToppCell(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CCDC146 NEK10 DNAAF3 CFAP54 PRR29 CFAP46

1.40e-0418818665ba5cbb403518026e9040379fb5d99339ea977d8
ToppCellCOVID-19-kidney-VWF+PLVAP+VCAM1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLT4 KALRN LRRC32 SH2D3C PPP1R16B NCOA7

1.44e-041891866c121817ddad164e9cfe382c43d0cbc9215508d02
DiseaseColorectal Carcinoma

RASGRF2 KALRN LAMA1 OBSCN IPP GRID1 HPS3 KCNH4 NF1 AKAP9 SH3TC1 ABCD4 VRTN SMAD4

9.89e-0570217814C0009402
Diseasecombined oxidative phosphorylation deficiency (implicated_via_orthology)

FASTKD2 MTO1

1.08e-0431782DOID:0060286 (implicated_via_orthology)
Diseaseresponse to acetylsalicylate

DOK6 DNAAF3 KCNQ1

1.14e-04161783GO_1903492
Diseasesolanidine measurement

CYP2D7 CYP2D6

2.15e-0441782EFO_0800966
Diseasecolon cancer (is_marker_for)

ATG101 RICTOR NF1 SMAD4

4.50e-04591784DOID:219 (is_marker_for)
Diseasefractalkine measurement

MED16 CCL17

5.34e-0461782EFO_0020395
Diseaselung small cell carcinoma (is_implicated_in)

RICTOR KMT2D MTOR

6.33e-04281783DOID:5409 (is_implicated_in)
DiseaseMalignant neoplasm of breast

AMFR CYP2D6 RASGRF2 KALRN UBR4 OBSCN MED14 TNIP1 CTIF KMT2D LMF2 NF1 AKAP9 MTOR TIMELESS GOLGB1

8.35e-04107417816C0006142
Diseaseprogrammed cell death 1 ligand 2 measurement

DHX36 PDCD1LG2

9.89e-0481782EFO_0008268
DiseaseBladder Neoplasm

AMFR TRPV1 KMT2D MTOR ESPL1

1.63e-031401785C0005695
DiseaseMalignant neoplasm of urinary bladder

AMFR TRPV1 KMT2D MTOR ESPL1

1.69e-031411785C0005684
DiseaseCongenital long QT syndrome

AKAP9 KCNQ1

1.92e-03111782cv:C1141890
Diseasechildhood gender nonconformity

WAPL GRID1 KIAA1549L

2.23e-03431783EFO_0020103
DiseaseLong QT syndrome

AKAP9 KCNQ1

2.30e-03121782cv:C0023976
Diseasepotassium measurement

NEK10 SH3TC1 NUP93

2.54e-03451783EFO_0009283
DiseaseAcute Confusional Senile Dementia

AMFR CYP2D6 SLC30A4 CRH

3.09e-03991784C0546126
DiseaseAlzheimer's Disease, Focal Onset

AMFR CYP2D6 SLC30A4 CRH

3.09e-03991784C0750900
DiseaseAlzheimer Disease, Early Onset

AMFR CYP2D6 SLC30A4 CRH

3.09e-03991784C0750901
DiseasePresenile dementia

AMFR CYP2D6 SLC30A4 CRH

3.09e-03991784C0011265
DiseaseAlzheimer Disease, Late Onset

AMFR CYP2D6 SLC30A4 CRH

3.09e-03991784C0494463
DiseaseKartagener syndrome (implicated_via_orthology)

DNAAF3 ODAD3

3.14e-03141782DOID:0050144 (implicated_via_orthology)
Diseasechromosome-type aberration frequency

STAG3L4 SLC2A12

3.14e-03141782EFO_0009861
DiseaseFamilial Alzheimer Disease (FAD)

AMFR CYP2D6 SLC30A4 CRH

3.20e-031001784C0276496
DiseaseAlzheimer's Disease

AMFR CYP2D6 SLC30A4 CRH

3.32e-031011784C0002395
Diseaseaspartate aminotransferase measurement

RAPGEF6 KALRN HECTD4 OBSCN MUC19 IPP ST7L NF1 SH3TC1 MTOR DSTYK MYO15A GCN1

3.45e-0390417813EFO_0004736
Diseaseacute graft vs. host disease, donor genotype effect measurement

KALRN TMEM131

3.61e-03151782EFO_0004599, EFO_0007892
Diseasequinate measurement

GRID1 KCNQ1

3.61e-03151782EFO_0021167
Diseasealcohol consumption measurement

WAPL RASGRF2 ZNF618 CLDN25 GRID1 NBEA ADGRV1 LRPPRC NF1 AKAP9 AP1G1 CADPS MTOR CDK5RAP2 MYO15A FRMD5

3.61e-03124217816EFO_0007878
Diseasemean platelet volume

KALRN DOCK8 U2SURP TENT5C ST7L CMIP DSTYK FBXO28 PPP1R16B KCNQ1 MCF2L ESPL1 S1PR4 GP5

3.68e-03102017814EFO_0004584
DiseaseRomano-Ward Syndrome

AKAP9 KCNQ1

4.11e-03161782C0035828
DiseaseX-21410 measurement

FAM200A PTCD1

4.11e-03161782EFO_0800813
DiseaseMetastatic melanoma

FLT4 NEK10 MTOR

4.27e-03541783C0278883
DiseaseCiliopathies

MKKS ADGRV1 DNAAF3 IQCB1

4.50e-031101784C4277690
Diseasecholesterol to total lipids in large HDL percentage

CMIP CELSR2 NUP93

4.50e-03551783EFO_0022234
Diseaseplasma beta-amyloid 1-40 measurement

DNAAF3 KCNQ1

4.64e-03171782EFO_0005659
Diseasebanks of the superior temporal sulcus volume measurement

GRID1 AP1G1

4.64e-03171782EFO_0010286
Diseasefibrinogen measurement, factor VII measurement

RAPGEF6 HECTD4 MCF2L

5.22e-03581783EFO_0004619, EFO_0004623
Diseasecholesteryl esters to total lipids in large HDL percentage

CMIP CELSR2 NUP93

5.48e-03591783EFO_0022248
Diseasefree cholesterol to total lipids in medium HDL percentage

CMIP CELSR2 NUP93

5.74e-03601783EFO_0022282
DiseaseBrugada syndrome

NCOA7 MYO18B

5.78e-03191782MONDO_0015263
Diseasebasal cell carcinoma

CYP27B1 ADGRV1 CCDC88B DSTYK MYO15A

5.90e-031891785EFO_0004193

Protein segments in the cluster

PeptideGeneStartEntry
LLDQLHNSLRIDLSM

UNC13A

936

Q9UPW8
QRFLTDVLHEVMLLD

TRHDE

486

Q9UKU6
LLRAVHNEGMQVLSL

AKAP9

2946

Q99996
LHILSSLRLIMQVAL

CFAP54

221

Q96N23
LNLLTRAHSILTEQM

CFAP54

2506

Q96N23
LQSEHDRAQMLLAEL

CCDC88B

1161

A6NC98
MLTRSLLLEVIELHA

CTIF

561

O43310
AMSAILDVNEQLHLL

HTR3E

71

A5X5Y0
LLLDMVVHNDRLLST

H2AB1

86

P0C5Y9
LLLDMVVHNDRLLST

H2AB2

86

P0C5Z0
ESFLISLLEVHLMNI

ADGRV1

2536

Q8WXG9
MLLLDERHDAHLLIT

AP1G2

91

O75843
AGLRLLSEHLTMLQV

CMIP

701

Q8IY22
GMESFLSHILVERLV

CFAP46

2481

Q8IYW2
LSHILVERLVAMNLQ

CFAP46

2486

Q8IYW2
ELQVARILMVASHGL

CLDN25

76

C9JDP6
MLALVTLLLGASLQH

CCL17

6

Q92583
HIQSARALMVVAVLL

CLDN19

76

Q8N6F1
AMRLTALLARALVHL

ADCK5

551

Q3MIX3
RSTITLQLREGHVML

CELSR2

1661

Q9HCU4
LSALLVMAVTHRDIA

DNHD1

1571

Q96M86
EVTSMARILHSLLDL

DNHD1

2216

Q96M86
THRIGQLRETLLDMS

ABCD4

341

O14678
RLAQLSEVAMHSLGL

BIK

76

Q13323
ASLLASELVQLHMQL

CAMSAP1

871

Q5T5Y3
TIAKHLEAMLITRLQ

FAM200A

121

Q8TCP9
SQDLLMEHIQEIRTL

CDK5RAP2

1391

Q96SN8
IRHNLSEVLLATMNI

NUP93

741

Q8N1F7
AMLDNSFERLLLHAV

R3HDM4

211

Q96D70
GLTEEMIQLLRSHRI

RAD51D

11

O75771
SFTELARIVLLRHGM

RAB40B

166

Q12829
MRNHTEITEFILLGL

OR6C1

1

Q96RD1
SHINFRLALIERMLE

PGBD4

481

Q96DM1
LMLSLELQLHQIAAL

PDCD1LG2

6

Q9BQ51
RQILIELHGMTSERQ

INTS8

526

Q75QN2
IIAADMLQLTEVVHL

IPP

111

Q9Y573
QHRRGLLVSLNELMI

SLC2A12

161

Q8TD20
LLLDERQDVHLLMTN

AP1G1

91

O43747
AELELQMALAQILTH

CYP27B1

461

O15528
LFEMVQRLTLDHRLN

CADPS

681

Q9ULU8
AALILVIAMDNALHA

OR52D1

46

Q9H346
EMEQLLLHSQERLVS

C22orf46

191

C9J442
NMHRIIAIDRIGVTL

MKKS

306

Q9NPJ1
LALITDMLHQLLSLH

KCNQ1

606

P51787
MESLLQHLDRFSELL

FANCF

1

Q9NPI8
SMREHVLNLAALTLQ

MYO15A

1896

Q9UKN7
RTLLLTHRVDTIGQM

MTO1

61

Q9Y2Z2
GLIIQVMATELAHSL

PHKA1

921

P46020
LLQHLRQDLGMESTS

LRRC75A

76

Q8NAA5
RTLLEAEMLAFHINA

KIAA1109

451

Q2LD37
LGEILVQMSDTQRHL

BAIAP2L2

71

Q6UXY1
RVELAVMLNLTERHI

PDX1

176

P52945
ISELNIVENLLMILH

NEK10

246

Q6ZWH5
EHNVLNSRRGILTLM

MUC19

571

Q7Z5P9
MILLRASEVRQLLHN

PCED1B

1

Q96HM7
SAVHLLSRLEDLQEM

KALRN

196

O60229
INRHLTELLALMSQL

VEPH1

196

Q14D04
QLSRELRHIMGLLQA

KCNH4

896

Q9UQ05
LQHSAADIARAEMLL

LAMB1

1561

P07942
SELHLMDRDLLQIIF

LRPPRC

296

P42704
ALAAAMRTLVKEHLI

TUBGCP2

291

Q9BSJ2
ASVRETVLRGLMELH

GCN1

1096

Q92616
RMALTLHHVVLLQAD

KIAA1549L

1156

Q6ZVL6
RRDLANMTGLLHLSL

LRFN3

76

Q9BTN0
LGTAQLTLLHAMLAL

AP5B1

316

Q2VPB7
LDLTFHLLREVLEMA

CRH

161

P06850
SLMNRAELLLHVTIA

HECTD4

1051

Q9Y4D8
LSSRLHVELMELLAA

PLA2G4F

241

Q68DD2
SMIHSLILNLSLADL

GPR151

71

Q8TDV0
VRATILLGELLHMAN

RICTOR

421

Q6R327
SSIAVLLIMERLHRD

DSTYK

726

Q6XUX3
LRLLRVMEHVQTTLL

PKD1L2

1036

Q7Z442
LSLQLEVLHSQTLML

MED14

301

O60244
LRSDDQDLTRMIHIL

MED16

51

Q9Y2X0
GNMTLVILIRTDSHL

OR9G4

56

Q8NGQ1
HILHLDLRSENMIIT

OBSCN

7786

Q5VST9
MLLDLSHNALETLEL

LRRC32

366

Q14392
VILHSVLRLNSAEAM

OR56B4

226

Q8NH76
MASHVDLLTELQLLE

PPP1R16B

1

Q96T49
LNAMIEAVESFLRHI

PLEKHG6

336

Q3KR16
NLISMAALENLLRHT

PRAMEF12

386

O95522
AEHSLELMLLSRQIN

FRMD5

436

Q7Z6J6
QVEEAMLAVLHTVLL

ATG101

16

Q9BSB4
SINLDRILLDIHIFM

CKAP5

1726

Q14008
LALDHRMEVLIASLE

ESPL1

1781

Q14674
MELAHSLLLNEEALA

HEATR5B

1

Q9P2D3
DLLVLHLSDLIRMAF

HEATR5B

1286

Q9P2D3
VNVLESLHMVSRLAK

E2F8

161

A0AVK6
GLLMTHLNSLDVQLA

DOCK8

66

Q8NF50
AVARHMLIFSLALEE

DNAAF3

86

Q8N9W5
TSAALMNIRILHIEG

GNE

121

Q9Y223
ATLAIAEQHERLMLE

DOK6

226

Q6PKX4
NDALIVLIHLLMLES

FBXO7

196

Q9Y3I1
AFLTQLDELLTEHRM

CYP2D6

246

P10635
MLTLQDRLSLRFIEH

FRMPD3

206

Q5JV73
AVLLSIRHLMELNAL

DHX36

666

Q9H2U1
EELFLLLQSLVMATH

F8A1;

316

P23610
TLHEMLEILINRLFD

CENPK

211

Q9BS16
DILAAVETRLSLLNM

FBXO28

141

Q9NVF7
NDDILNMVIVIHSLL

C1orf112

151

Q9NSG2
RLTDTLGRLSHILEM

CBS

491

P35520
QLHFMDQLLDTIRSL

HAUS7

126

Q99871
ESLAILRRHVMSELL

MCF2L

626

O15068
GTLRVHELQSLSEML

MAPKBP1

501

O60336
LQSVLHLMENGALVL

FAM118B

146

Q9BPY3
LMAESHQEILILLRQ

IQCB1

236

Q15051
RLSRELQLSMLEIVH

IQCB1

361

Q15051
SLQVSQDLLDLMHTL

GBF1

1491

Q92538
EILDLVHSALGRMTV

GRID1

266

Q9ULK0
MVLLEQLFLDHNALR

GP5

121

P40197
ISMILSEAIRRIHNG

PRPSAP2

341

O60256
LRAVREVLHTGLAML

DALRD3

521

Q5D0E6
IAALMLARHQEELLL

CCDC177

341

Q9NQR7
AISIAQMEKRLLHGL

FBXL5

306

Q9UKA1
FHETLEQRLLVTELM

HAUS4

111

Q9H6D7
LITRLLELERLQHMT

FAM217A

286

Q8IXS0
NLISMAALENLLRHT

PRAMEF8

386

Q5VWM4
VLENLLVLAAITSHM

S1PR4

61

O95977
HMEALLQSLVIVLLG

SLFN13

546

Q68D06
QMHVLETLDLLVLRA

GARNL3

531

Q5VVW2
HIGTSALMDLLLRLV

PPP6R2

156

O75170
ARMLTELLFELHVAA

FAM114A1

366

Q8IWE2
AVNTAIHTGLMLRLD

OR13A1

171

Q8NGR1
RKMLIQILTELEHSG

MTOR

731

P42345
ETGLHLMRRALAVLQ

RUNDC1

336

Q96C34
SLRNIHTLLDAAMLQ

SYVN1

506

Q86TM6
LLETARGVTNMALAH

TCP11L1

66

Q9NUJ3
LLLMLRATHLQEGSR

RGSL1

131

A5PLK6
EILSNLREHQLRLMS

RAPGEF6

36

Q8TEU7
HVNLLLIEARMQAEL

SESN1

466

Q9Y6P5
LLVDLVTSMDHQERL

PLCD4

121

Q9BRC7
ETIHLMALRELNIAF

TLR10

461

Q9BXR5
LLSEAHLLVRAALMD

HPS3

521

Q969F9
HLLVRAALMDASQLE

HPS3

526

Q969F9
LMTLVLTTALLDDQH

LMF2

276

Q9BU23
ALLENMHIEQLARRL

NCOA7

781

Q8NI08
LTLLHRELQALTEAM

PTGIS

126

Q16647
LSAMELAEQITLLDH

RASGRF2

1001

O14827
ALLTLNHMGRRISQI

SLC22A10

396

Q63ZE4
LQLQHSLRLLEMAEA

ODAD3

181

A5D8V7
VSVLDALLHTLMVLQ

OR7G3

151

Q8NG95
VLAAMNHRSLILLDE

FASTKD2

351

Q9NYY8
VDSLEQLTGIRMLRH

GPRASP2

691

Q96D09
RDQLMTVLANVTHLL

LAMA1

656

P25391
SLLEIMQIRDFTQLH

LAMA1

1701

P25391
FTLLGERLMLHTNTV

NBEA

791

Q8NFP9
RALQLLDEVLHTMPI

SMAD4

531

Q13485
SLIQILDSELFELMH

SGSM2

886

O43147
ATALIIRQIADHSLM

SHOC1

1006

Q5VXU9
LQRLHATHNLMELLI

SHPRH

1066

Q149N8
HMEALLQSLVIVLLG

SLFN11

546

Q7Z7L1
HMALALSITLGDRLN

SH3TC1

1176

Q8TE82
QHGVILDIMEQLLSS

MROH2B

1256

Q7Z745
MLLRLNALLHALNEV

URB1

1411

O60287
GVMEDQRSIILHLIS

OSBPL10

391

Q9BXB5
IQGLDLLTAMVLVNH

SERPINA9

191

Q86WD7
LMGHERRQTLNLISL

TENT5C

321

Q5VWP2
NLLALIHRMIEFVVR

U2SURP

426

O15042
SSHGRVLSLLVAMLL

AMFR

181

Q9UKV5
TQALHQRLLLEMEAI

CCDC146

381

Q8IYE0
AFLTQLDELLTEHRM

CYP2D7

246

A0A087X1C5
NLMLHLQRLETTLSV

TNIP1

156

Q15025
LLHSLEQGMKVLATR

TRIM69

276

Q86WT6
NLISMAALENLLRHT

PRAMEF7

386

Q5VXH5
LHVLEIVSLMFRDQN

TIMELESS

216

Q9UNS1
EVMLETCRLLVSLGH

ZNF599

36

Q96NL3
QVSLMHSARIVADLL

ZBTB12

71

Q9Y330
RTLQARSMHEVIELL

ZNF618

651

Q5T7W0
LLLHHRSMESANILL

ARHGAP40

571

Q5TG30
LHIAIERRNMALVTL

TRPV1

206

Q8NER1
GALVSLLMLLHSAAR

SLC26A11

456

Q86WA9
LLLANTAAHIIRLML

ARHGAP28

556

Q9P2N2
LMTSLVRVALQLSLH

STAG3L4

101

Q8TBR4
LHLVMTLVVAAARAE

TMEM131

46

Q92545
RALMSELKILIHIGN

FLT4

891

P35916
LENITTGHLAMETLL

WAPL

786

Q7Z5K2
IAQEAMEALLVLHQL

NF1

541

P21359
MEALLVLHQLDSIDL

NF1

546

P21359
LTMLNIHENLLESLL

ST7L

326

Q8TDW4
MELLETLHLGLASSR

IGSF9

1096

Q9P2J2
VSLLHSLLQDITMIN

nan

216

Q6ZUG5
LDLDLRTELNLHQMA

MYO18B

766

Q8IUG5
LMVQLLHKLSVRAAD

EMG1

136

Q92979
HMLTDLSAIILTLLA

SLC30A4

146

O14863
AQMHQLLLSRLVAGA

PRR29

56

P0C7W0
QLRLDLLERFHTMSI

SH2D3C

631

Q8N5H7
SIELFHTMGRALLSL

TTC23

136

Q5W5X9
SAMLHVEALERQLFL

PTCD1

376

O75127
SLELRARTVVEMLLH

VRTN

101

Q9H8Y1
TRGMLQSTDLILKHL

VN1R3

36

Q9BXE9
SALNEVHLVVMRLLS

UBR4

3046

Q5T4S7
GHERRQTLNLITMLA

TENT5A

371

Q96IP4
RLINLLEEVFHLMET

VIRMA

626

Q69YN4
SLMAEIGIHSRTSLL

WDR87

976

Q6ZQQ6
EMSALRTHRIQILQG

ZNF106

1101

Q9H2Y7
LRLIHADINVMENTI

ZC4H2

66

Q9NQZ6
TLSIQIALHSLLMED

VPS13D

1661

Q5THJ4
MLSRLSGLANVVLHE

GOLGB1

1

Q14789
ALMNVEVALHRGLLT

KMT2D

5076

O14686
SNLHGLDRMVVLLSV

MXRA5

1931

Q9NR99
NLQRLLEMVATHVGS

NDC80

581

O14777