Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR2F2 DRD5 MAS1L HTR4 OR1B1 OR5B2 MLNR MAS1 FPR3 OR6C74 ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D OR2F1 PTGER4 TAS2R10 PTPRC CELSR3 ACKR3 MRGPRX1 GPR75 AGTR1 PKD1 MRGPRX3 TACR1 TAS2R40 ADGRA3 HRH3 GABRA6

4.03e-10135312931GO:0004888
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR2F2 DRD5 MAS1L HTR4 OR1B1 OR5B2 MLNR MAS1 FPR3 OR6C74 OR2F1 PTGER4 TAS2R10 CELSR3 ACKR3 MRGPRX1 GPR75 AGTR1 MRGPRX3 TACR1 TAS2R40 ADGRA3 HRH3

1.06e-0888412923GO:0004930
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIN2A GRIN2B GRIN2C GRIN2D

1.14e-0781294GO:0022849
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN2A GRIN2B GRIN2C GRIN2D

1.14e-0781294GO:0004972
GeneOntologyMolecularFunctionneurotransmitter receptor activity

DRD5 HTR4 GRIN2A GRIN2B GRIN2C GRIN2D HRH3 GABRA6

2.76e-071001298GO:0030594
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D HRH3 GABRA6

5.49e-07751297GO:0098960
GeneOntologyMolecularFunctionligand-gated calcium channel activity

GRIN2A GRIN2B GRIN2C GRIN2D PKD2

1.55e-06311295GO:0099604
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

MAS1L MLNR MAS1 FPR3 MRGPRX1 AGTR1 MRGPRX3 TACR1

2.43e-061331298GO:0008528
GeneOntologyMolecularFunctionangiotensin receptor activity

MAS1L MAS1 AGTR1

2.61e-0651293GO:0001595
GeneOntologyMolecularFunctionpeptide receptor activity

MAS1L MLNR MAS1 FPR3 MRGPRX1 AGTR1 MRGPRX3 TACR1

3.57e-061401298GO:0001653
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIN2A GRIN2B GRIN2C GRIN2D

3.71e-06171294GO:0004970
GeneOntologyMolecularFunctionendopeptidase inhibitor activity

SERPINA3 GBP1 GBP2 SERPINA12 HMSD GBP5 ITIH6 SERPINA9

2.25e-051801298GO:0004866
GeneOntologyMolecularFunctiontransporter activity

ATP8B4 ABCA13 MFSD2B ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D ATP13A2 ABCA10 SLC52A3 CLPTM1L SLC12A1 SLCO1C1 TMEM184A PKD1 PKD2 SLC4A4 SLC38A6 KCNH5 SLC23A3 GABRA6

2.54e-05128912922GO:0005215
GeneOntologyMolecularFunctionglutamate receptor activity

GRIN2A GRIN2B GRIN2C GRIN2D

2.60e-05271294GO:0008066
GeneOntologyMolecularFunctionpeptidase inhibitor activity

SERPINA3 GBP1 GBP2 SERPINA12 HMSD GBP5 ITIH6 SERPINA9

2.96e-051871298GO:0030414
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GRIN2A GRIN2B GRIN2C GRIN2D GABRA6

3.33e-05571295GO:1904315
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GRIN2A GRIN2B GRIN2C GRIN2D GABRA6

4.28e-05601295GO:0099529
GeneOntologyMolecularFunctionendopeptidase regulator activity

SERPINA3 GBP1 GBP2 SERPINA12 HMSD GBP5 ITIH6 SERPINA9

4.94e-052011298GO:0061135
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GRIN2A GRIN2B GRIN2C GRIN2D GABRA6

6.30e-05651295GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GRIN2A GRIN2B GRIN2C GRIN2D GABRA6

6.30e-05651295GO:0022824
GeneOntologyMolecularFunctionglutamate binding

GRIN2A GRIN2B GRIN2D

9.10e-05141293GO:0016595
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GRIN2A GRIN2B GRIN2C GRIN2D GABRA6

1.42e-04771295GO:0005230
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

GBP6 ATP8B4 GBP7 ABCA13 LRRK2 GBP1 GBP2 ABCC9 YTHDC2 ATP13A2 ABCA10 GBP4 GBP5 KIF28P AQR

1.46e-0477512915GO:0017111
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D PKD2 KCNH5

1.83e-041821297GO:0005244
GeneOntologyMolecularFunctioncalcium channel activity

GRIN2A GRIN2B GRIN2C GRIN2D PKD1 PKD2

1.92e-041291296GO:0005262
GeneOntologyMolecularFunctionvoltage-gated channel activity

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D PKD2 KCNH5

1.95e-041841297GO:0022832
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCA13 MFSD2B ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D ATP13A2 ABCA10 SLC52A3 SLC12A1 SLCO1C1 PKD1 PKD2 SLC4A4 SLC38A6 KCNH5 SLC23A3 GABRA6

2.06e-04118012919GO:0022857
GeneOntologyMolecularFunctionangiotensin type II receptor activity

MAS1 AGTR1

2.46e-0441292GO:0004945
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D PKD2 GABRA6

2.62e-041931297GO:0015276
GeneOntologyMolecularFunctionpeptidase regulator activity

SERPINA3 GBP1 GBP2 SERPINA12 HMSD GBP5 ITIH6 SERPINA9

2.69e-042571298GO:0061134
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA13 ABCC9 ATP13A2 ABCA10

2.81e-04491294GO:0140359
GeneOntologyMolecularFunctionligand-gated channel activity

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D PKD2 GABRA6

2.96e-041971297GO:0022834
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D PKD2

2.99e-041401296GO:0099094
GeneOntologyMolecularFunctionpyrophosphatase activity

GBP6 ATP8B4 GBP7 ABCA13 LRRK2 GBP1 GBP2 ABCC9 YTHDC2 ATP13A2 ABCA10 GBP4 GBP5 KIF28P AQR

3.43e-0483912915GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

GBP6 ATP8B4 GBP7 ABCA13 LRRK2 GBP1 GBP2 ABCC9 YTHDC2 ATP13A2 ABCA10 GBP4 GBP5 KIF28P AQR

3.47e-0484012915GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

GBP6 ATP8B4 GBP7 ABCA13 LRRK2 GBP1 GBP2 ABCC9 YTHDC2 ATP13A2 ABCA10 GBP4 GBP5 KIF28P AQR

3.47e-0484012915GO:0016818
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

GRIN2A GRIN2B GRIN2C GRIN2D PKD1 PKD2

4.49e-041511296GO:0015085
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIN2A GRIN2B GRIN2D

4.83e-04241293GO:0099507
GeneOntologyMolecularFunctionmolecular function inhibitor activity

SERPINA3 GBP6 LRRK2 GBP1 GBP2 SERPINA12 HMSD GBP5 PKD1 PKD2 ITIH6 SERPINA9

4.90e-0459612912GO:0140678
GeneOntologyMolecularFunctionenzyme inhibitor activity

SERPINA3 GBP6 LRRK2 GBP1 GBP2 SERPINA12 HMSD GBP5 ITIH6 SERPINA9

5.32e-0443512910GO:0004857
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

GRIN2A GRIN2B GRIN2C GRIN2D SLC38A6

6.00e-041051295GO:0015171
GeneOntologyMolecularFunctionserine-type endopeptidase inhibitor activity

SERPINA3 SERPINA12 HMSD ITIH6 SERPINA9

6.00e-041051295GO:0004867
GeneOntologyMolecularFunction3'-5' RNA helicase activity

YTHDC2 AQR

6.11e-0461292GO:0034458
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

GRIN2A GRIN2B GRIN2C GRIN2D SLC52A3 SLCO1C1 SLC4A4 SLC38A6

6.43e-042931298GO:0008514
GeneOntologyMolecularFunctionclathrin binding

CLTCL1 LRRK2 PICALM SNAP91

7.37e-04631294GO:0030276
GeneOntologyMolecularFunctionextracellularly glutamate-gated ion channel activity

GRIN2A GRIN2B

8.51e-0471292GO:0005234
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D SLC12A1 PKD1 PKD2 SLC4A4 KCNH5

8.88e-0446512910GO:0046873
GeneOntologyMolecularFunctionmethyl-CpG binding

LRWD1 ZBTB4 ZBTB21

1.04e-03311293GO:0008327
GeneOntologyMolecularFunctionspectrin binding

GBP1 GBP2 PTPRC

1.36e-03341293GO:0030507
GeneOntologyMolecularFunctiongated channel activity

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D PKD2 KCNH5 GABRA6

1.49e-033341298GO:0022836
GeneOntologyMolecularFunctionlipid transporter activity

ATP8B4 ABCA13 MFSD2B ABCA10 CLPTM1L SLCO1C1

1.74e-031961296GO:0005319
GeneOntologyMolecularFunctionmonoatomic cation channel activity

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D PKD1 PKD2 KCNH5

1.76e-033431298GO:0005261
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

GRIN2A GRIN2B GRIN2C GRIN2D SLCO1C1 SLC38A6

2.28e-032071296GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

GRIN2A GRIN2B GRIN2C GRIN2D SLCO1C1 SLC38A6

2.34e-032081296GO:0005342
GeneOntologyMolecularFunctionGDP phosphatase activity

GBP1 GBP2

2.62e-03121292GO:0004382
GeneOntologyMolecularFunctionclathrin heavy chain binding

PICALM SNAP91

2.62e-03121292GO:0032050
GeneOntologyMolecularFunctionmonoatomic ion channel activity

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D PKD1 PKD2 KCNH5 GABRA6

2.99e-034591299GO:0005216
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

ABCC9 GRIN2A GRIN2D PKD2 KCNH5

3.09e-031521295GO:0022843
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D ATP13A2 SLC12A1 PKD1 PKD2 SLC4A4 KCNH5

3.88e-0366412911GO:0008324
GeneOntologyMolecularFunctionamyloid-beta binding

FPR3 GRIN2A GRIN2B PICALM

4.34e-031021294GO:0001540
GeneOntologyMolecularFunctionpeptide binding

MAS1 FPR3 GRIN2A GRIN2B PICALM MRGPRX1 MRGPRX3

4.65e-033181297GO:0042277
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

STAB2 OLR1

4.68e-03161292GO:0005041
GeneOntologyMolecularFunctionneuropeptide receptor activity

MRGPRX1 MRGPRX3 TACR1

4.88e-03531293GO:0008188
GeneOntologyMolecularFunctiontransmembrane transporter binding

LRRK2 ABCC9 PKD1 PKD2 KCNH5

5.22e-031721295GO:0044325
GeneOntologyMolecularFunction1-phosphatidylinositol binding

PICALM SNAP91

5.29e-03171292GO:0005545
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D ATP13A2 SLC12A1 PKD1 PKD2 SLC4A4 KCNH5 GABRA6

5.31e-0379312912GO:0015075
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA13 ABCC9 ATP13A2 ABCA10

5.49e-031091294GO:0042626
GeneOntologyMolecularFunctionG protein activity

GBP1 GBP2 GBP5

6.58e-03591293GO:0003925
GeneOntologyMolecularFunctionGTPase activity

GBP6 GBP7 LRRK2 GBP1 GBP2 GBP4 GBP5

6.75e-033411297GO:0003924
GeneOntologyMolecularFunctionchannel activity

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D PKD1 PKD2 KCNH5 GABRA6

7.10e-035251299GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D PKD1 PKD2 KCNH5 GABRA6

7.19e-035261299GO:0022803
GeneOntologyMolecularFunctionnucleoside diphosphate phosphatase activity

GBP1 GBP2

7.29e-03201292GO:0017110
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D SLC12A1 PKD1 PKD2 SLC4A4 KCNH5

7.55e-0362712910GO:0022890
GeneOntologyMolecularFunctionATP hydrolysis activity

ATP8B4 ABCA13 ABCC9 YTHDC2 ATP13A2 ABCA10 KIF28P AQR

7.95e-034411298GO:0016887
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

STAB2 OLR1

8.03e-03211292GO:0030228
GeneOntologyMolecularFunctionG protein-coupled serotonin receptor activity

HTR4 HRH3

8.79e-03221292GO:0004993
GeneOntologyBiologicalProcesscytolysis

GBP7 GBP1 GBP2 HMSD GBP4 GBP5

4.55e-11121286GO:0019835
GeneOntologyBiologicalProcesscytolysis in another organism

GBP7 GBP1 GBP2 GBP4 GBP5

1.05e-0991285GO:0051715
GeneOntologyBiologicalProcesspositive regulation of pyroptotic inflammatory response

GBP7 GBP1 GBP2 GBP4 GBP5

1.05e-0991285GO:0140639
GeneOntologyBiologicalProcessadhesion of symbiont to host

GBP6 GBP7 GBP1 GBP2 GBP4

1.22e-07201285GO:0044406
GeneOntologyBiologicalProcessstartle response

GRIN2A GRIN2B GRIN2C GRIN2D NLGN3 SLITRK6

1.91e-07411286GO:0001964
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR2F2 DRD5 MAS1L HTR4 OR1B1 OR5B2 MLNR MAS1 FPR3 OR6C74 LRRK2 MFSD2B OR2F1 PTGER4 ADCY3 TAS2R10 CELSR3 ACKR3 MRGPRX1 GPR75 AGTR1 MRGPRX3 TACR1 TAS2R40 ADGRA3 HRH3

3.69e-07139512826GO:0007186
GeneOntologyBiologicalProcesspositive regulation of AIM2 inflammasome complex assembly

GBP1 GBP2 GBP5

9.30e-0741283GO:0140973
GeneOntologyBiologicalProcessregulation of terminal button organization

PICALM NLGN3 SNAP91

9.30e-0741283GO:2000331
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle endocytosis

ABCA13 LRRK2 PICALM SNAP91

9.69e-07131284GO:1900244
GeneOntologyBiologicalProcessexcitatory chemical synaptic transmission

GRIN2A GRIN2B GRIN2C GRIN2D

2.43e-06161284GO:0098976
GeneOntologyBiologicalProcessmodulation of excitatory postsynaptic potential

LRRK2 GRIN2A GRIN2B GRIN2C GRIN2D NLGN3

3.11e-06651286GO:0098815
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle recycling

ABCA13 LRRK2 PICALM SNAP91

3.16e-06171284GO:1903423
GeneOntologyBiologicalProcessdefense response to protozoan

GBP6 GBP7 GBP1 GBP2 GBP4

4.14e-06391285GO:0042832
GeneOntologyBiologicalProcessregulation of AIM2 inflammasome complex assembly

GBP1 GBP2 GBP5

4.61e-0661283GO:0140971
GeneOntologyBiologicalProcesscellular response to interferon-beta

GBP6 GBP7 GBP1 GBP2 GBP4

5.33e-06411285GO:0035458
GeneOntologyBiologicalProcessresponse to protozoan

GBP6 GBP7 GBP1 GBP2 GBP4

6.02e-06421285GO:0001562
GeneOntologyBiologicalProcesspyroptotic inflammatory response

GBP7 GBP1 GBP2 GBP4 GBP5

6.02e-06421285GO:0070269
GeneOntologyBiologicalProcesscalcium-mediated signaling

LRRK2 GBP1 GRIN2A GRIN2B GRIN2C GRIN2D PTPRC ACKR3 AGTR1 PKD2

6.41e-0626612810GO:0019722
GeneOntologyBiologicalProcesspositive regulation of excitatory postsynaptic potential

GRIN2A GRIN2B GRIN2C GRIN2D NLGN3

6.78e-06431285GO:2000463
GeneOntologyBiologicalProcesspositive regulation of synaptic transmission, glutamatergic

GRIN2A GRIN2B GRIN2C GRIN2D NLGN3

6.78e-06431285GO:0051968
GeneOntologyBiologicalProcessresponse to interferon-beta

GBP6 GBP7 GBP1 GBP2 GBP4

1.18e-05481285GO:0035456
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle clustering

PICALM NLGN3 SNAP91

1.28e-0581283GO:2000809
GeneOntologyBiologicalProcessAIM2 inflammasome complex assembly

GBP1 GBP2 GBP5

1.28e-0581283GO:0140970
GeneOntologyBiologicalProcessassociative learning

RAG1 DRD5 GRIN2A GRIN2B ADCY3 NLGN3 TACR1

1.69e-051301287GO:0008306
GeneOntologyBiologicalProcessterminal button organization

PICALM NLGN3 SNAP91

1.91e-0591283GO:0072553
GeneOntologyBiologicalProcessionotropic glutamate receptor signaling pathway

GRIN2A GRIN2B GRIN2C GRIN2D

2.22e-05271284GO:0035235
GeneOntologyBiologicalProcessregulation of synaptic transmission, glutamatergic

LRRK2 GRIN2A GRIN2B GRIN2C GRIN2D NLGN3

2.34e-05921286GO:0051966
GeneOntologyBiologicalProcesspositive regulation of inhibitory postsynaptic potential

GRIN2A GRIN2B NLGN3

2.71e-05101283GO:0097151
GeneOntologyBiologicalProcesspositive regulation of inflammatory response

GBP7 LRRK2 GBP1 GBP2 PTGER4 GBP4 GBP5 AGTR1

2.79e-051931288GO:0050729
GeneOntologyBiologicalProcessglutamate receptor signaling pathway

GRIN2A GRIN2B GRIN2C GRIN2D NLGN3

3.26e-05591285GO:0007215
GeneOntologyBiologicalProcessbehavior

RAG1 DRD5 RASGRF1 LRRK2 GRIN2A GRIN2B GRIN2D PTGER4 PICALM ADCY3 NLGN3 MRGPRX1 AGTR1 MRGPRX3 TACR1 SLITRK6 HRH3

3.71e-0589112817GO:0007610
GeneOntologyBiologicalProcessmodulation of inhibitory postsynaptic potential

GRIN2A GRIN2B NLGN3

4.93e-05121283GO:0098828
GeneOntologyBiologicalProcessregulation of synaptic vesicle clustering

PICALM NLGN3 SNAP91

4.93e-05121283GO:2000807
GeneOntologyBiologicalProcessregulation of synaptic vesicle endocytosis

ABCA13 LRRK2 PICALM SNAP91

5.04e-05331284GO:1900242
GeneOntologyBiologicalProcesslearning

RAG1 DRD5 GRIN2A GRIN2B ADCY3 NLGN3 TACR1 HRH3

5.43e-052121288GO:0007612
GeneOntologyBiologicalProcesscellular response to type II interferon

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

7.83e-051141286GO:0071346
GeneOntologyBiologicalProcesspositive regulation of cytosolic calcium ion concentration

FPR3 PTGER4 ACKR3 AGTR1 PKD1 PKD2 TACR1 HRH3

7.99e-052241288GO:0007204
GeneOntologyBiologicalProcessdetection of mechanical stimulus

GRIN2A GRIN2B GRIN2D PKD1 PKD2

1.04e-04751285GO:0050982
GeneOntologyBiologicalProcessligand-gated ion channel signaling pathway

GRIN2A GRIN2B GRIN2C GRIN2D

1.09e-04401284GO:1990806
GeneOntologyBiologicalProcesslearning or memory

RAG1 DRD5 RASGRF1 GRIN2A GRIN2B PICALM ADCY3 NLGN3 TACR1 HRH3

1.13e-0437312810GO:0007611
GeneOntologyBiologicalProcessprotein heterotetramerization

GRIN2B PKD1 PKD2

1.23e-04161283GO:0051290
GeneOntologyBiologicalProcessregulation of postsynaptic membrane potential

LRRK2 GRIN2A GRIN2B GRIN2C GRIN2D NLGN3 GABRA6

1.33e-041801287GO:0060078
GeneOntologyBiologicalProcesskilling of cells of another organism

GBP7 LYZL6 GBP1 GBP2 GBP4 GBP5

1.55e-041291286GO:0031640
GeneOntologyBiologicalProcessdisruption of cell in another organism

GBP7 LYZL6 GBP1 GBP2 GBP4 GBP5

1.55e-041291286GO:0141061
GeneOntologyBiologicalProcessresponse to mechanical stimulus

GRIN2A GRIN2B GRIN2D PTGER4 PKD1 PKD2 TACR1 SLITRK6

1.57e-042471288GO:0009612
GeneOntologyBiologicalProcessregulation of synaptic vesicle recycling

ABCA13 LRRK2 PICALM SNAP91

1.58e-04441284GO:1903421
GeneOntologyBiologicalProcessdetection of stimulus

OR2F2 OR1B1 OR5B2 OR6C74 GRIN2A GRIN2B GRIN2D OR2F1 TAS2R10 LPO PKD1 PKD2 TACR1 TAS2R40

1.60e-0472212814GO:0051606
GeneOntologyBiologicalProcessexcitatory postsynaptic potential

LRRK2 GRIN2A GRIN2B GRIN2C GRIN2D NLGN3

1.62e-041301286GO:0060079
GeneOntologyBiologicalProcessregulation of neuronal synaptic plasticity

RASGRF1 GRIN2A GRIN2B GRIN2C GRIN2D

1.68e-04831285GO:0048168
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

LRRK2 GRIN2A GRIN2B GRIN2C GRIN2D NLGN3

1.76e-041321286GO:0035249
GeneOntologyBiologicalProcessdisruption of anatomical structure in another organism

GBP7 LYZL6 GBP1 GBP2 GBP4 GBP5

1.76e-041321286GO:0141060
GeneOntologyBiologicalProcessdrinking behavior

AGTR1 TACR1 HRH3

1.78e-04181283GO:0042756
GeneOntologyBiologicalProcessregulation of presynapse organization

PICALM NLGN3 SNAP91 SLITRK6

1.89e-04461284GO:0099174
GeneOntologyBiologicalProcessdirectional locomotion

GRIN2A GRIN2C

2.27e-0441282GO:0033058
GeneOntologyBiologicalProcessresponse to type II interferon

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

2.51e-041411286GO:0034341
GeneOntologyBiologicalProcesscognition

RAG1 DRD5 RASGRF1 GRIN2A GRIN2B PICALM ADCY3 NLGN3 TACR1 HRH3

3.12e-0442312810GO:0050890
GeneOntologyBiologicalProcesschemical synaptic transmission, postsynaptic

LRRK2 GRIN2A GRIN2B GRIN2C GRIN2D NLGN3

3.14e-041471286GO:0099565
GeneOntologyBiologicalProcesssynaptic vesicle clustering

PICALM NLGN3 SNAP91

3.30e-04221283GO:0097091
GeneOntologyBiologicalProcesssynaptic vesicle endocytosis

ABCA13 LRRK2 PICALM NLGN3 SNAP91

3.31e-04961285GO:0048488
GeneOntologyBiologicalProcessdefense response to Gram-positive bacterium

GBP6 STAB2 GBP7 GBP1 GBP2 GBP4

3.50e-041501286GO:0050830
GeneOntologyBiologicalProcessresponse to chloroquine

MRGPRX1 MRGPRX3

3.77e-0451282GO:1902349
GeneOntologyBiologicalProcesssensitization

DRD5 GRIN2B

3.77e-0451282GO:0046960
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

GRIN2A GRIN2B GRIN2C GRIN2D PTPRC AGTR1 PKD2

4.17e-042171287GO:0097553
GeneOntologyBiologicalProcessmaintenance of gastrointestinal epithelium

SERPINA3 HTR4 MUC4

4.30e-04241283GO:0030277
GeneOntologyBiologicalProcessangiotensin-activated signaling pathway

MAS1L MAS1 AGTR1

4.30e-04241283GO:0038166
GeneOntologyBiologicalProcesspresynaptic endocytosis

ABCA13 LRRK2 PICALM NLGN3 SNAP91

4.38e-041021285GO:0140238
GeneOntologyBiologicalProcesspositive regulation of inflammasome-mediated signaling pathway

GBP1 GBP2 GBP5

5.47e-04261283GO:0141087
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception of pain

GRIN2A GRIN2B GRIN2D

5.47e-04261283GO:0050966
GeneOntologyBiologicalProcesscellular response to oxygen-containing compound

GBP6 DRD5 MAS1L GBP7 MAS1 LRRK2 GBP1 GBP2 ABCC9 GRIN2A GRIN2D PTGER4 ADCY3 SERPINA12 PHEX GBP4 GBP5 AGTR1 PKD2 HRH3

6.09e-04145012820GO:1901701
GeneOntologyBiologicalProcessinhibitory postsynaptic potential

GRIN2A GRIN2B NLGN3

6.12e-04271283GO:0060080
GeneOntologyBiologicalProcesspositive regulation of synaptic transmission

GRIN2A GRIN2B GRIN2C GRIN2D PTGER4 NLGN3 TACR1

6.37e-042331287GO:0050806
GeneOntologyBiologicalProcesssynaptic vesicle recycling

ABCA13 LRRK2 PICALM NLGN3 SNAP91

6.45e-041111285GO:0036465
GeneOntologyBiologicalProcesscell killing

GBP7 LYZL6 GBP1 GBP2 PTPRC GBP4 GBP5 MUC4

6.71e-043071288GO:0001906
GeneOntologyBiologicalProcessregulation of membrane potential

LRRK2 ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D NLGN3 TACR1 SLC4A4 KCNH5 GABRA6

7.33e-0455912811GO:0042391
GeneOntologyBiologicalProcessinflammatory response

SERPINA3 GBP7 MAS1 FPR3 LRRK2 GBP1 GBP2 PTGER4 OLR1 PTPRC GBP4 GBP5 MRGPRX1 AGTR1 MRGPRX3 TACR1

7.41e-04104312816GO:0006954
GeneOntologyBiologicalProcessresponse to alcohol

GRIN2A GRIN2B LCT PTGER4 ADCY3 PTPRC TACR1 HRH3

7.46e-043121288GO:0097305
GeneOntologyBiologicalProcessregulation of synaptic vesicle transport

LRRK2 PICALM

7.86e-0471282GO:1902803
GeneOntologyBiologicalProcessregulation of nervous system process

LRRK2 GRIN2A GRIN2B GRIN2C GRIN2D NLGN3

7.90e-041751286GO:0031644
GeneOntologyBiologicalProcessdetection of abiotic stimulus

GRIN2A GRIN2B GRIN2D PKD1 PKD2 TACR1

7.90e-041751286GO:0009582
GeneOntologyBiologicalProcessresponse to nitrogen compound

TMEM67 SERPINA3 DRD5 MAS1L MAS1 LRRK2 ABCC9 GRIN2A GRIN2B GRIN2D SERPINA12 PHEX CCNG1 MRGPRX1 AGTR1 PKD2 MRGPRX3 HRH3

8.73e-04127212818GO:1901698
GeneOntologyBiologicalProcesschemosensory behavior

ADCY3 MRGPRX1 MRGPRX3

9.24e-04311283GO:0007635
GeneOntologyBiologicalProcessprotein heterooligomerization

GRIN2B PKD1 PKD2

9.24e-04311283GO:0051291
GeneOntologyBiologicalProcessnegative regulation of protein localization to plasma membrane

LYPLAL1 GBP1 PICALM

9.24e-04311283GO:1903077
GeneOntologyBiologicalProcessdefense response to bacterium

GBP6 STAB2 GBP7 LYZL6 GBP1 GBP2 GBP4 GBP5 LPO

9.69e-044051289GO:0042742
GeneOntologyBiologicalProcesssynaptic vesicle localization

LRRK2 PICALM NLGN3 SNAP91

9.97e-04711284GO:0097479
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR2F2 OR1B1 OR5B2 OR6C74 GRIN2A GRIN2B GRIN2D OR2F1 TAS2R10 LPO TAS2R40

1.02e-0358212811GO:0050906
GeneOntologyBiologicalProcesspresynapse organization

PICALM NLGN3 SNAP91 SLITRK6

1.11e-03731284GO:0099172
GeneOntologyBiologicalProcessnegative regulation of protein localization to cell periphery

LYPLAL1 GBP1 PICALM

1.11e-03331283GO:1904376
GeneOntologyBiologicalProcessbrain renin-angiotensin system

AGTR1 TACR1

1.34e-0391282GO:0002035
GeneOntologyBiologicalProcessregulation of inflammatory response

GBP7 MAS1 LRRK2 GBP1 GBP2 PTGER4 PTPRC GBP4 GBP5 AGTR1

1.41e-0351512810GO:0050727
GeneOntologyBiologicalProcessvisual learning

RAG1 DRD5 GRIN2A NLGN3

1.42e-03781284GO:0008542
GeneOntologyBiologicalProcessepithelial structure maintenance

SERPINA3 HTR4 MUC4

1.44e-03361283GO:0010669
GeneOntologyBiologicalProcesscell surface receptor signaling pathway via JAK-STAT

GBP7 PIGU PTGER4 PTPRC PKD1 PKD2

1.49e-031981286GO:0007259
GeneOntologyCellularComponenthost cell part

GBP6 GBP7 GBP1 GBP2 GBP4

4.94e-1161295GO:0033643
GeneOntologyCellularComponenthost intracellular part

GBP6 GBP7 GBP1 GBP2 GBP4

4.94e-1161295GO:0033646
GeneOntologyCellularComponenthost cell cytoplasm part

GBP6 GBP7 GBP1 GBP2 GBP4

4.94e-1161295GO:0033655
GeneOntologyCellularComponentsymbiont-containing vacuole

GBP6 GBP7 GBP1 GBP2 GBP4

4.94e-1161295GO:0020003
GeneOntologyCellularComponentsymbiont-containing vacuole membrane

GBP6 GBP7 GBP1 GBP2 GBP4

4.94e-1161295GO:0020005
GeneOntologyCellularComponenthost intracellular region

GBP6 GBP7 GBP1 GBP2 GBP4

4.94e-1161295GO:0043656
GeneOntologyCellularComponenthost cell cytoplasm

GBP6 GBP7 GBP1 GBP2 GBP4

4.94e-1161295GO:0030430
GeneOntologyCellularComponenthost cellular component

GBP6 GBP7 GBP1 GBP2 GBP4

2.37e-08151295GO:0018995
GeneOntologyCellularComponentNMDA selective glutamate receptor complex

GRIN2A GRIN2B GRIN2C GRIN2D

1.70e-0791294GO:0017146
GeneOntologyCellularComponentsymbiont cell surface

GBP1 GBP2 GBP5

1.26e-0581293GO:0106139
GeneOntologyCellularComponentother organism part

GBP1 GBP2 GBP5

1.88e-0591293GO:0044217
GeneOntologyCellularComponentpostsynaptic specialization membrane

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D NLGN3 CELSR3 GABRA6

3.59e-052011298GO:0099634
GeneOntologyCellularComponentpolycystin complex

PKD1 PKD2

3.78e-0521292GO:0002133
GeneOntologyCellularComponentcell surface

STAB2 MAS1 LYZL6 GRIN2A GRIN2B LCT PICALM NLGN3 ICOS PTPRC SLC12A1 ACKR3 MRGPRX1 PKD1 TACR1 SLITRK6 SLC4A4 ADGRA3 KCNH5

5.16e-05111112919GO:0009986
GeneOntologyCellularComponentparallel fiber to Purkinje cell synapse

GRIN2A GRIN2B PICALM SNAP91

1.42e-04431294GO:0098688
GeneOntologyCellularComponentcytoplasmic vesicle membrane

TMEM67 ATP8B4 STAB2 CLTCL1 GBP7 ABCA13 LRRK2 GBP1 GBP2 GRIN2A GRIN2B ATP13A2 OLR1 PTPRC TMEM184A GBP5 SNAP91 PKD1 PKD2 ELAPOR1

1.48e-04130712920GO:0030659
GeneOntologyCellularComponentionotropic glutamate receptor complex

GRIN2A GRIN2B GRIN2C GRIN2D

1.70e-04451294GO:0008328
GeneOntologyCellularComponentvesicle membrane

TMEM67 ATP8B4 STAB2 CLTCL1 GBP7 ABCA13 LRRK2 GBP1 GBP2 GRIN2A GRIN2B ATP13A2 OLR1 PTPRC TMEM184A GBP5 SNAP91 PKD1 PKD2 ELAPOR1

1.77e-04132512920GO:0012506
GeneOntologyCellularComponentpostsynaptic membrane

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D PICALM NLGN3 CELSR3 SNAP91 GABRA6

2.12e-0440512910GO:0045211
GeneOntologyCellularComponentneurotransmitter receptor complex

GRIN2A GRIN2B GRIN2C GRIN2D

2.56e-04501294GO:0098878
GeneOntologyCellularComponentciliary membrane

TMEM67 DRD5 ADCY3 PKD1 PKD2

3.55e-04981295GO:0060170
GeneOntologyCellularComponentpostsynaptic density membrane

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D CELSR3

4.34e-041571296GO:0098839
GeneOntologyCellularComponentexcitatory synapse

GRIN2A GRIN2B PICALM NLGN3 SNAP91

5.32e-041071295GO:0060076
GeneOntologyCellularComponentsomatodendritic compartment

DRD5 HTR4 RASGRF1 LRRK2 GRIN2A GRIN2B PTGER4 ATP13A2 PICALM CCNG1 NLGN3 SNAP91 MRGPRX1 AGTR1 MRGPRX3 TACR1 HRH3 GABRA6

5.46e-04122812918GO:0036477
GeneOntologyCellularComponentmonoatomic ion channel complex

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D PKD1 PKD2 KCNH5 GABRA6

5.73e-043781299GO:0034702
GeneOntologyCellularComponentextrinsic component of presynaptic endocytic zone membrane

PICALM SNAP91

7.78e-0471292GO:0098894
GeneOntologyCellularComponentpostsynaptic specialization

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D PICALM NLGN3 CELSR3 SNAP91 GABRA6

1.14e-0350312910GO:0099572
GeneOntologyCellularComponentmigrasome

PKD1 PKD2

1.32e-0391292GO:0140494
GeneOntologyCellularComponentpresynaptic active zone membrane

GRIN2B GRIN2D CELSR3 SNAP91

1.39e-03781294GO:0048787
GeneOntologyCellularComponentneuron to neuron synapse

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D PICALM NLGN3 CELSR3 SNAP91 GABRA6

1.52e-0352312910GO:0098984
GeneOntologyCellularComponentclathrin-coated pit

CLTCL1 PICALM SNAP91 ACKR3

1.52e-03801294GO:0005905
GeneOntologyCellularComponentpresynaptic membrane

GRIN2A GRIN2B GRIN2D PICALM CELSR3 SNAP91 GABRA6

1.68e-032771297GO:0042734
GeneOntologyCellularComponentcell body

DRD5 RASGRF1 LRRK2 GRIN2B PTGER4 ATP13A2 PICALM CCNG1 NLGN3 SNAP91 MRGPRX1 MRGPRX3 TACR1 GABRA6

1.80e-0392912914GO:0044297
GeneOntologyCellularComponentneuronal cell body

DRD5 RASGRF1 LRRK2 GRIN2B PTGER4 ATP13A2 PICALM CCNG1 NLGN3 SNAP91 MRGPRX1 MRGPRX3 GABRA6

1.98e-0383512913GO:0043025
GeneOntologyCellularComponenttransporter complex

ATP8B4 ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D PKD1 PKD2 KCNH5 GABRA6

2.20e-0355012910GO:1990351
GeneOntologyCellularComponentneuronal cell body membrane

MRGPRX1 MRGPRX3 GABRA6

2.37e-03431293GO:0032809
GeneOntologyCellularComponentasymmetric synapse

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D PICALM NLGN3 CELSR3 SNAP91

2.85e-034771299GO:0032279
GeneOntologyCellularComponentcell body membrane

MRGPRX1 MRGPRX3 GABRA6

3.05e-03471293GO:0044298
GeneOntologyCellularComponentpresynaptic endocytic zone membrane

PICALM SNAP91

3.28e-03141292GO:0098835
GeneOntologyCellularComponentsynaptic membrane

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D PICALM NLGN3 CELSR3 SNAP91 GABRA6

3.34e-0358312910GO:0097060
GeneOntologyCellularComponentbasolateral plasma membrane

RASGRF1 SLCO1C1 LPO AGTR1 PKD1 PKD2 SLC4A4

3.76e-033201297GO:0016323
GeneOntologyCellularComponentclathrin coat

CLTCL1 PICALM SNAP91

5.01e-03561293GO:0030118
GeneOntologyCellularComponenttransmembrane transporter complex

ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D PKD1 PKD2 KCNH5 GABRA6

5.19e-035231299GO:1902495
GeneOntologyCellularComponentcell projection membrane

TMEM67 DRD5 GRIN2A ADCY3 PKD1 PKD2 MUC4 GABRA6

5.34e-034311298GO:0031253
GeneOntologyCellularComponentpresynaptic endocytic zone

PICALM SNAP91

5.42e-03181292GO:0098833
GeneOntologyCellularComponentextrinsic component of presynaptic membrane

PICALM SNAP91

5.42e-03181292GO:0098888
GeneOntologyCellularComponentbasal plasma membrane

RASGRF1 SLCO1C1 LPO AGTR1 PKD1 PKD2 SLC4A4

6.47e-033541297GO:0009925
GeneOntologyCellularComponentdendrite

DRD5 HTR4 RASGRF1 LRRK2 GRIN2A GRIN2B CCNG1 NLGN3 AGTR1 TACR1 HRH3 GABRA6

6.86e-0385812912GO:0030425
GeneOntologyCellularComponentpostsynaptic density

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D PICALM CELSR3 SNAP91

6.96e-034511298GO:0014069
GeneOntologyCellularComponentdendritic tree

DRD5 HTR4 RASGRF1 LRRK2 GRIN2A GRIN2B CCNG1 NLGN3 AGTR1 TACR1 HRH3 GABRA6

6.98e-0386012912GO:0097447
GeneOntologyCellularComponentsperm midpiece

LYZL6 PCDH11X TACR1

7.27e-03641293GO:0097225
GeneOntologyCellularComponentclathrin coat of coated pit

PICALM SNAP91

7.35e-03211292GO:0030132
MousePhenoabnormal kidney physiology

SERPINA3 DRD5 MAS1 LRRK2 ADCY3 PHEX PTPRC SLC12A1 LPO AGTR1 PKD1 PKD2 SLC4A4

2.99e-0637210213MP:0002136
MousePhenodecreased circulating renin level

ADCY3 SLC12A1 AGTR1

4.36e-05101023MP:0003353
MousePhenoabnormal circulating renin level

ADCY3 SLC12A1 AGTR1 SLC4A4

5.52e-05291024MP:0003349
DomainGBP_C

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

1.56e-11101246PF02841
DomainG_GB1_RHD3_dom

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

3.41e-11111246IPR030386
DomainGuanylate-bd_N

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

3.41e-11111246IPR015894
DomainGuanylate-bd_C

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

3.41e-11111246IPR003191
DomainGBP

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

3.41e-11111246PF02263
DomainG_GB1_RHD3

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

3.41e-11111246PS51715
DomainGPCR_Rhodpsn_7TM

OR2F2 DRD5 MAS1L HTR4 OR1B1 OR5B2 MLNR MAS1 FPR3 OR6C74 OR2F1 PTGER4 ACKR3 MRGPRX1 GPR75 AGTR1 MRGPRX3 TACR1 HRH3

9.08e-0867012419IPR017452
Domain7tm_1

OR2F2 DRD5 MAS1L HTR4 OR1B1 OR5B2 MLNR MAS1 FPR3 OR6C74 OR2F1 PTGER4 ACKR3 MRGPRX1 GPR75 AGTR1 MRGPRX3 TACR1 HRH3

1.07e-0767712419PF00001
DomainG_PROTEIN_RECEP_F1_1

OR2F2 DRD5 MAS1L HTR4 OR1B1 OR5B2 MLNR MAS1 FPR3 OR6C74 OR2F1 PTGER4 ACKR3 MRGPRX1 GPR75 AGTR1 MRGPRX3 TACR1 HRH3

1.28e-0768512419PS00237
DomainG_PROTEIN_RECEP_F1_2

OR2F2 DRD5 MAS1L HTR4 OR1B1 OR5B2 MLNR MAS1 FPR3 OR6C74 OR2F1 PTGER4 ACKR3 MRGPRX1 GPR75 AGTR1 MRGPRX3 TACR1 HRH3

1.47e-0769112419PS50262
DomainGPCR_Rhodpsn

OR2F2 DRD5 MAS1L HTR4 OR1B1 OR5B2 MLNR MAS1 FPR3 OR6C74 OR2F1 PTGER4 ACKR3 MRGPRX1 GPR75 AGTR1 MRGPRX3 TACR1 HRH3

1.50e-0769212419IPR000276
DomainNMDAR2_C

GRIN2A GRIN2B GRIN2C

2.86e-0731243PF10565
DomainNMDAR2_C

GRIN2A GRIN2B GRIN2C

2.86e-0731243IPR018884
DomainMRGPCRFAMILY

MAS1L MAS1 MRGPRX1 MRGPRX3

5.89e-07111244IPR026234
DomainLig_chan-Glu_bd

GRIN2A GRIN2B GRIN2C GRIN2D

5.27e-06181244PF10613
DomainGlu/Gly-bd

GRIN2A GRIN2B GRIN2C GRIN2D

5.27e-06181244IPR019594
DomainLig_chan-Glu_bd

GRIN2A GRIN2B GRIN2C GRIN2D

5.27e-06181244SM00918
DomainIontro_rcpt

GRIN2A GRIN2B GRIN2C GRIN2D

5.27e-06181244IPR001320
DomainIono_rcpt_met

GRIN2A GRIN2B GRIN2C GRIN2D

5.27e-06181244IPR001508
DomainLig_chan

GRIN2A GRIN2B GRIN2C GRIN2D

5.27e-06181244PF00060
DomainPBPe

GRIN2A GRIN2B GRIN2C GRIN2D

5.27e-06181244SM00079
DomainClathrin_AP_2

PICALM SNAP91

4.37e-0521242IPR014712
Domain-

PICALM SNAP91

4.37e-05212421.20.58.150
DomainSerpin_dom

SERPINA3 SERPINA12 HMSD SERPINA9

9.25e-05361244IPR023796
DomainANF_lig-bd_rcpt

GRIN2A GRIN2B GRIN2C GRIN2D

1.03e-04371244IPR001828
DomainANF_receptor

GRIN2A GRIN2B GRIN2C GRIN2D

1.03e-04371244PF01094
DomainSERPIN

SERPINA3 SERPINA12 HMSD SERPINA9

1.03e-04371244PS00284
DomainSerpin

SERPINA3 SERPINA12 HMSD SERPINA9

1.15e-04381244PF00079
DomainPeripla_BP_I

GRIN2A GRIN2B GRIN2C GRIN2D

1.27e-04391244IPR028082
DomainSerpin_fam

SERPINA3 SERPINA12 HMSD SERPINA9

1.27e-04391244IPR000215
DomainANTH_dom

PICALM SNAP91

2.60e-0441242IPR011417
DomainANTH

PICALM SNAP91

2.60e-0441242PF07651
DomainGPS

CELSR3 PKD1 ADGRA3

1.47e-03341243SM00303
DomainENTH

PICALM SNAP91

1.53e-0391242PS50942
DomainENTH

PICALM SNAP91

1.53e-0391242SM00273
DomainGPS

CELSR3 PKD1 ADGRA3

1.60e-03351243PF01825
DomainGPS

CELSR3 PKD1 ADGRA3

1.74e-03361243PS50221
DomainGPS

CELSR3 PKD1 ADGRA3

1.88e-03371243IPR000203
DomainSERPIN

SERPINA3 SERPINA12 SERPINA9

1.88e-03371243SM00093
DomainLeu-rich_rpt_4

LRWD1 LRRK2

1.90e-03101242IPR025875
DomainENTH

PICALM SNAP91

1.90e-03101242IPR013809
DomainLRR_4

LRWD1 LRRK2

1.90e-03101242PF12799
DomainARM-type_fold

CLTCL1 INTS7 LRRK2 USP24 RALGAPA2 URB1 MROH7 LRBA

1.93e-033391248IPR016024
DomainLRR

LRWD1 LRRK2 STK11IP PKD1 SLITRK6 ADGRA3

2.25e-032011246PS51450
DomainGFP-like

STAB2 HMCN1

2.31e-03111242IPR023413
Domain-

STAB2 HMCN1

2.31e-031112422.40.155.10
DomainPKD_channel

PKD1 PKD2

2.31e-03111242PF08016
DomainPKD1_2_channel

PKD1 PKD2

2.31e-03111242IPR013122
DomainABC_A

ABCA13 ABCA10

2.76e-03121242IPR026082
DomainCarboxylesterase_B_CS

TG NLGN3

3.25e-03131242IPR019819
DomainCARBOXYLESTERASE_B_2

TG NLGN3

3.78e-03141242PS00941
DomainCOesterase

TG NLGN3

3.78e-03141242PF00135
DomainCarbesteraseB

TG NLGN3

3.78e-03141242IPR002018
DomainABC_tran

ABCA13 ABCC9 ABCA10

3.97e-03481243PF00005
DomainABC_TRANSPORTER_2

ABCA13 ABCC9 ABCA10

3.97e-03481243PS50893
Domain-

GBP6 GBP7 ABCA13 LRRK2 GBP1 GBP2 ABCC9 YTHDC2 ABCA10 GBP4 GBP5 AQR

4.04e-03746124123.40.50.300
DomainABC_TRANSPORTER_1

ABCA13 ABCC9 ABCA10

4.21e-03491243PS00211
DomainABC_transporter-like

ABCA13 ABCC9 ABCA10

4.46e-03501243IPR003439
DomainLRR_TYP

LRWD1 LRRK2 PKD1 SLITRK6 ADGRA3

6.57e-031771245SM00369
DomainLeu-rich_rpt_typical-subtyp

LRWD1 LRRK2 PKD1 SLITRK6 ADGRA3

6.57e-031771245IPR003591
Domain7TM_GPCR_Srsx

DRD5 HTR4 MLNR AGTR1

6.62e-031121244SM01381
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

DRD5 HTR4 MLNR MAS1 FPR3 GRIN2A GRIN2B GRIN2C GRIN2D PTGER4 AGTR1 TACR1 HRH3 GABRA6

2.70e-092729314M13380
PathwayKEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B GRIN2C GRIN2D

8.83e-095934M47667
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

OR2F2 DRD5 MAS1L HTR4 MLNR MAS1 FPR3 OR2F1 PTGER4 ACKR3 GPR75 AGTR1 HRH3

1.48e-082609313M39397
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B GRIN2C GRIN2D

2.64e-086934M47668
PathwayWP_NRXN1_DELETION_SYNDROME

GRIN2A GRIN2B GRIN2C GRIN2D NLGN3

8.98e-0818935M48098
PathwayWP_GPCRS_NONODORANT

DRD5 HTR4 MAS1 PTGER4 TAS2R10 CELSR3 ACKR3 AGTR1 TACR1 TAS2R40 HRH3

1.36e-062669311MM15843
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B GRIN2C GRIN2D

2.29e-0615934M47691
PathwayWP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV

GRIN2A GRIN2B GRIN2C GRIN2D NLGN3

2.30e-0633935M39875
PathwayREACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS

GRIN2A GRIN2C GRIN2D

2.75e-065933MM15655
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B GRIN2C GRIN2D

5.06e-0618934M47761
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B GRIN2C GRIN2D

6.38e-0619934M47677
PathwayBIOCARTA_NOS1_PATHWAY

GRIN2A GRIN2B GRIN2C GRIN2D

7.93e-0620934MM1445
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

GRIN2A GRIN2B GRIN2C GRIN2D

9.75e-0621934M27736
PathwayBIOCARTA_NOS1_PATHWAY

GRIN2A GRIN2B GRIN2C GRIN2D

9.75e-0621934M11650
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

GRIN2A GRIN2B GRIN2C GRIN2D

9.75e-0621934M838
PathwayREACTOME_NEGATIVE_REGULATION_OF_NMDA_RECEPTOR_MEDIATED_NEURONAL_TRANSMISSION

GRIN2A GRIN2B GRIN2C GRIN2D

9.75e-0621934M27944
PathwayREACTOME_LONG_TERM_POTENTIATION

GRIN2A GRIN2B GRIN2C GRIN2D

1.43e-0523934M27949
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

DRD5 HTR4 GRIN2A GRIN2C GRIN2D ADCY3 AGTR1 TACR1

2.25e-05178938M2890
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

GRIN2A GRIN2B GRIN2C GRIN2D NLGN3 SLITRK6

2.30e-0587936M27617
PathwayWP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION

GRIN2A GRIN2B GRIN2C GRIN2D ADCY3

3.01e-0555935M39763
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

GRIN2A GRIN2B GRIN2C GRIN2D NLGN3

3.28e-0556935M27616
PathwayREACTOME_INTERFERON_GAMMA_SIGNALING

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

4.53e-0598936M965
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_LIGAND_GATED_CA2_CHANNEL

GRIN2A GRIN2C GRIN2D

5.86e-0512933M47953
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

GRIN2A GRIN2C GRIN2D NLGN3 SLITRK6

7.84e-0567935MM15327
PathwayREACTOME_NEURONAL_SYSTEM

RASGRF1 ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D ADCY3 NLGN3 SLITRK6 KCNH5 GABRA6

8.06e-054119311M735
PathwayWP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION

GRIN2A GRIN2B GRIN2C GRIN2D

8.90e-0536934M39831
PathwayREACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS

GRIN2A GRIN2B GRIN2C GRIN2D

1.97e-0444934M27934
PathwayREACTOME_GPCR_LIGAND_BINDING

DRD5 HTR4 MLNR FPR3 PTGER4 TAS2R10 ACKR3 AGTR1 TACR1 TAS2R40 HRH3

2.29e-044639311M507
PathwayWP_NOCGMPPKG_MEDIATED_NEUROPROTECTION

GRIN2A GRIN2B GRIN2C GRIN2D

2.55e-0447934M39531
PathwayREACTOME_RAS_ACTIVATION_UPON_CA2_INFLUX_THROUGH_NMDA_RECEPTOR

RASGRF1 GRIN2B GRIN2D

2.92e-0420933M17670
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

GRIN2A GRIN2C GRIN2D

2.92e-0420933MM15485
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

DRD5 HTR4 MLNR FPR3 PTGER4 ACKR3 AGTR1 TACR1 HRH3

3.24e-04330939M18334
PathwayWP_SYNAPTIC_SIGNALING_ASSOCIATED_WITH_AUTISM_SPECTRUM_DISORDER

GRIN2A GRIN2B GRIN2C GRIN2D

3.24e-0450934M39822
PathwayREACTOME_NEURONAL_SYSTEM

ABCC9 GRIN2A GRIN2C GRIN2D ADCY3 NLGN3 SLITRK6 KCNH5 GABRA6

3.62e-04335939MM14503
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

RASGRF1 GRIN2A GRIN2B GRIN2C GRIN2D

3.88e-0494935M2843
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

GRIN2A GRIN2C GRIN2D

3.91e-0422933MM15104
PathwayKEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS

GRIN2A GRIN2B GRIN2C GRIN2D

4.06e-0453934M3812
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

RASGRF1 GRIN2A GRIN2B GRIN2C GRIN2D ADCY3 GABRA6

4.09e-04205937M752
PathwayREACTOME_GPCR_LIGAND_BINDING

DRD5 HTR4 FPR3 PTGER4 TAS2R10 ACKR3 AGTR1 TACR1 TAS2R40 HRH3

5.30e-044309310MM15160
PathwayREACTOME_CARGO_RECOGNITION_FOR_CLATHRIN_MEDIATED_ENDOCYTOSIS

CLTCL1 PICALM SNAP91 AGTR1 TACR1

6.44e-04105935M27752
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

DRD5 HTR4 GRIN2A GRIN2B GRIN2C GRIN2D SLC52A3 NLGN3 AGTR1

6.98e-04367939M48346
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING

RASGRF1 GRIN2B GRIN2D

8.08e-0428933M837
PathwayWP_SARSCOV2_AND_ACE2_RECEPTOR_MOLECULAR_MECHANISMS

MAS1 AGTR1

8.85e-047932M39867
PathwayKEGG_LONG_TERM_POTENTIATION

GRIN2A GRIN2B GRIN2C GRIN2D

1.17e-0370934M3115
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

HTR4 MAS1 FPR3 PTGER4 ACKR3 AGTR1

1.43e-03186936MM15994
PathwayWP_ALZHEIMERS_DISEASE

GRIN2A GRIN2B GRIN2C GRIN2D

1.44e-0374934MM15962
PathwayKEGG_PRIMARY_IMMUNODEFICIENCY

RAG1 ICOS PTPRC

1.56e-0335933M4085
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

GRIN2A GRIN2C GRIN2D

1.56e-0335933MM15109
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

DRD5 HTR4 FPR3 PTGER4 ACKR3 AGTR1 TACR1 HRH3

1.59e-03333938MM14963
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

RASGRF1 GRIN2A GRIN2B GRIN2C GRIN2D ADCY3 GABRA6

2.04e-03270937M15514
PathwayREACTOME_SIGNALING_BY_GPCR

DRD5 HTR4 MLNR FPR3 PTGER4 ADCY3 TAS2R10 ACKR3 AGTR1 TACR1 TAS2R40 HRH3

2.17e-037029312M746
PathwayWP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING

GRIN2A GRIN2B GRIN2C GRIN2D ADCY3

2.32e-03140935M42572
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

GRIN2A GRIN2C GRIN2D ADCY3 GABRA6

2.62e-03144935MM14501
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

DRD5 HTR4 HRH3

2.65e-0342933M5868
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

DRD5 HTR4 HRH3

2.65e-0342933MM14971
PathwayREACTOME_CLATHRIN_MEDIATED_ENDOCYTOSIS

CLTCL1 PICALM SNAP91 AGTR1 TACR1

2.70e-03145935M27753
PathwayKEGG_ABC_TRANSPORTERS

ABCA13 ABCC9 ABCA10

3.03e-0344933M11911
PathwayREACTOME_SIGNALING_BY_GPCR

DRD5 HTR4 FPR3 PTGER4 ADCY3 TAS2R10 ACKR3 AGTR1 TACR1 TAS2R40 HRH3

3.44e-036469311MM14962
PathwayWP_GPCRS_ODORANT

TAS2R10 MRGPRX1 GPR75 MRGPRX3 ADGRA3

3.80e-03157935MM15872
PathwayWP_RETT_SYNDROME

TAF1B GRIN2A GRIN2B

3.88e-0348933M39759
PathwayREACTOME_CARGO_RECOGNITION_FOR_CLATHRIN_MEDIATED_ENDOCYTOSIS

PICALM SNAP91 AGTR1 TACR1

4.61e-03102934MM15498
Pubmed

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

6.44e-148129616689661
Pubmed

Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

1.05e-1211129618025219
Pubmed

A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection.

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

6.04e-1119129621551061
Pubmed

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.

GBP7 GBP1 GBP2 GBP4 GBP5

8.08e-119129524739961
Pubmed

Functional correlation of NMDA receptor epsilon subunits expression with the properties of single-channel and synaptic currents in the developing cerebellum.

GRIN2A GRIN2B GRIN2C GRIN2D

1.81e-10412948699248
Pubmed

Role of the carboxy-terminal region of the GluR epsilon2 subunit in synaptic localization of the NMDA receptor channel.

GRIN2A GRIN2B GRIN2C GRIN2D

1.81e-10412949768843
Pubmed

Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.

GBP7 GBP1 GBP2 GBP4 GBP5

2.95e-1011129524715728
Pubmed

Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling.

GBP7 GBP1 GBP2 GBP4 GBP5

5.04e-1012129535906252
Pubmed

Synapse-selective impairment of NMDA receptor functions in mice lacking NMDA receptor epsilon 1 or epsilon 2 subunit.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-10512949147327
Pubmed

Heterozygous deletion of NR1 subunit of the NMDA receptor alters ethanol-related behaviors and regional expression of NR2 subunits in the brain.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-105129421945132
Pubmed

Roles of the glutamate receptor epsilon2 and delta2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-105129411488959
Pubmed

Differential distributions of the NMDA receptor channel subunit mRNAs in the mouse retina.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-10512947510577
Pubmed

Distinct spatiotemporal distributions of the N-methyl-D-aspartate receptor channel subunit mRNAs in the mouse cervical cord.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-10512947929904
Pubmed

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-105129426919761
Pubmed

Distinct distributions of five NMDA receptor channel subunit mRNAs in the brainstem.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-10512947518475
Pubmed

Distinct spatiotemporal expressions of five NMDA receptor channel subunit mRNAs in the cerebellum.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-10512947518474
Pubmed

Distinct gene expression of the N-methyl-D-aspartate receptor channel subunit in peripheral neurons of the mouse sensory ganglia and adrenal gland.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-10512948015722
Pubmed

Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-105129415003177
Pubmed

GABAA, GABAC, and NMDA receptor subunit expression in the suprachiasmatic nucleus and other brain regions.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-10512947723623
Pubmed

Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-105129412082569
Pubmed

Murine GBP-5, a new member of the murine guanylate-binding protein family, is coordinately regulated with other GBPs in vivo and in vitro.

GBP6 GBP1 GBP2 GBP5

9.01e-105129412396730
Pubmed

Unique features of different members of the human guanylate-binding protein family.

GBP1 GBP2 GBP4 GBP5

9.01e-105129417266443
Pubmed

Developmental changes in distribution of NMDA receptor channel subunit mRNAs.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-10512941493227
Pubmed

N-methyl-D-aspartic acid receptor structure and function.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-10512948036251
Pubmed

NMDA receptor activation by HIV-Tat protein is clade dependent.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-105129419020013
Pubmed

Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.

GBP1 GBP2 GBP4 GBP5

9.01e-105129421151871
Pubmed

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-105129426875626
Pubmed

Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-10512948756432
Pubmed

Differential interaction of NMDA receptor subtypes with the post-synaptic density-95 family of membrane associated guanylate kinase proteins.

GRIN2A GRIN2B GRIN2C GRIN2D

9.01e-105129418233995
Pubmed

A role for spermine oxidase as a mediator of reactive oxygen species production in HIV-Tat-induced neuronal toxicity.

GRIN2A GRIN2B GRIN2C GRIN2D

2.69e-096129423665428
Pubmed

Altered gene expression of the N-methyl-D-aspartate receptor channel subunits in Purkinje cells of the staggerer mutant mouse.

GRIN2A GRIN2B GRIN2C GRIN2D

2.69e-09612948996814
Pubmed

Cortical consequences of HIV-1 Tat exposure in rats are enhanced by chronic cocaine.

GRIN2A GRIN2B GRIN2C GRIN2D

2.69e-096129425760043
Pubmed

Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo.

GRIN2A GRIN2B GRIN2C GRIN2D

2.69e-09612949458051
Pubmed

NMDA receptor GluRepsilon/NR2 subunits are essential for postsynaptic localization and protein stability of GluRzeta1/NR1 subunit.

GRIN2A GRIN2B GRIN2C GRIN2D

2.69e-096129415317856
Pubmed

Early onset of NMDA receptor GluR epsilon 1 (NR2A) expression and its abundant postsynaptic localization in developing motoneurons of the mouse hypoglossal nucleus.

GRIN2A GRIN2B GRIN2C GRIN2D

6.27e-097129412103442
Pubmed

Human immunodeficiency virus-1 protein Tat induces excitotoxic loss of presynaptic terminals in hippocampal cultures.

GRIN2A GRIN2B GRIN2C GRIN2D

6.27e-097129423267846
Pubmed

Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death.

GRIN2A GRIN2B GRIN2C GRIN2D

6.27e-097129419036954
Pubmed

HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors.

GRIN2A GRIN2B GRIN2C GRIN2D

6.27e-097129422940423
Pubmed

Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia.

GRIN2A GRIN2B GRIN2C GRIN2D

6.27e-097129422833210
Pubmed

HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce neurotoxicity in human embryonic neurons.

GRIN2A GRIN2B GRIN2C GRIN2D

1.25e-08812948563977
Pubmed

Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity.

GRIN2A GRIN2B GRIN2C GRIN2D

1.25e-08812947695237
Pubmed

HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes.

GRIN2A GRIN2B GRIN2C GRIN2D

1.25e-088129417360663
Pubmed

Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120.

GRIN2A GRIN2B GRIN2C GRIN2D

1.25e-08812948724036
Pubmed

Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine.

GRIN2A GRIN2B GRIN2C GRIN2D

1.25e-08812948822372
Pubmed

Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-ß production.

GRIN2A GRIN2B GRIN2C GRIN2D

1.25e-088129421106831
Pubmed

Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures.

GRIN2A GRIN2B GRIN2C GRIN2D

1.25e-088129410448428
Pubmed

Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase.

GRIN2A GRIN2B GRIN2C GRIN2D

1.25e-08812948955056
Pubmed

Evidence of HIV type 1 glycoprotein 120 binding to recombinant N-methyl-D-aspartate receptor subunits expressed in a baculovirus system.

GRIN2A GRIN2B GRIN2C GRIN2D

1.25e-088129410555109
Pubmed

Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons.

GRIN2A GRIN2B GRIN2C GRIN2D

1.25e-08812948804048
Pubmed

The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid.

GRIN2A GRIN2B GRIN2C GRIN2D

1.25e-08812948845955
Pubmed

HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures.

GRIN2A GRIN2B GRIN2C GRIN2D

1.25e-08812948821747
Pubmed

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.

GBP6 GBP7 GBP1 GBP2 GBP4

1.26e-0821129519158679
Pubmed

Activation of cannabinoid type 2 receptors inhibits HIV-1 envelope glycoprotein gp120-induced synapse loss.

GRIN2A GRIN2B GRIN2C GRIN2D

2.24e-089129421670103
Pubmed

Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems.

GRIN2A GRIN2B GRIN2C GRIN2D

2.24e-089129417526495
Pubmed

Human immunodeficiency virus type 1 clade B and C gp120 differentially induce neurotoxin arachidonic acid in human astrocytes: implications for neuroAIDS.

GRIN2A GRIN2B GRIN2C GRIN2D

2.24e-089129421491143
Pubmed

D1/NMDA receptors and concurrent methamphetamine+ HIV-1 Tat neurotoxicity.

GRIN2A GRIN2B GRIN2C GRIN2D

2.24e-089129422552781
Pubmed

PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A.

GRIN2A GRIN2B GRIN2C GRIN2D

2.24e-08912949892651
Pubmed

Maternal stress produces learning deficits associated with impairment of NMDA receptor-mediated synaptic plasticity.

GRIN2A GRIN2B GRIN2C GRIN2D

2.24e-089129416554481
Pubmed

N-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neurons.

GRIN2A GRIN2B GRIN2C GRIN2D

3.73e-0810129419332541
Pubmed

Auditory pathway and auditory brainstem response in mice lacking NMDA receptor epsilon 1 and epsilon 4 subunits.

GRIN2A GRIN2C GRIN2D

4.99e-08312939718984
Pubmed

Regulated appearance of NMDA receptor subunits and channel functions during in vitro neuronal differentiation.

GRIN2A GRIN2B GRIN2D

4.99e-083129311920728
Pubmed

Long-term NR2B expression in the cerebellum alters granule cell development and leads to NR2A down-regulation and motor deficits.

GRIN2A GRIN2B GRIN2C

4.99e-083129315519237
Pubmed

Dual regulation of NR2B and NR2C expression by NMDA receptor activation in mouse cerebellar granule cell cultures.

GRIN2A GRIN2B GRIN2C

4.99e-083129318685090
Pubmed

Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels.

GRIN2A GRIN2C GRIN2D

4.99e-08312939480759
Pubmed

Molecular and genetic determinants of the NMDA receptor for superior learning and memory functions.

GRIN2A GRIN2B GRIN2D

4.99e-083129325360708
Pubmed

Climbing-fibre activation of NMDA receptors in Purkinje cells of adult mice.

GRIN2A GRIN2B GRIN2D

4.99e-083129317901118
Pubmed

HIV-1 Tat-mediated apoptosis in human blood-retinal barrier-associated cells.

GRIN2A GRIN2B GRIN2C GRIN2D

5.84e-0811129424739951
Pubmed

Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase.

GRIN2A GRIN2B GRIN2C GRIN2D

5.84e-081112948581564
Pubmed

CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins.

GRIN2A GRIN2B GRIN2C GRIN2D

5.84e-081112949647694
Pubmed

Effects of SDF-1alpha and gp120IIIB on apoptotic pathways in SK-N-SH neuroblastoma cells.

GRIN2A GRIN2B GRIN2C GRIN2D

5.84e-0811129416481105
Pubmed

Developmental rearrangements of cortical glutamate-NMDA receptor binding sites in late human gestation.

GRIN2A GRIN2B GRIN2C GRIN2D

8.74e-081212948665664
Pubmed

Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle.

GRIN2A GRIN2B GRIN2C GRIN2D

8.74e-0812129412815021
Pubmed

Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102.

GRIN2A GRIN2B GRIN2C GRIN2D

8.74e-0812129411937501
Pubmed

Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways.

GRIN2A GRIN2B GRIN2C GRIN2D

1.76e-0714129415749123
Pubmed

Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.

RASGRF1 GRIN2A GRIN2B GRIN2D

1.76e-0714129410373510
Pubmed

Molecular diversity of the NMDA receptor channel.

GRIN2A GRIN2B GRIN2C

1.99e-07412931377365
Pubmed

Heteromeric NMDA receptors: molecular and functional distinction of subtypes.

GRIN2A GRIN2B GRIN2C

1.99e-07412931350383
Pubmed

Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.

GRIN2A GRIN2C GRIN2D

1.99e-074129336309015
Pubmed

Differential expression and co-assembly of NMDA zeta 1 and epsilon subunits in the mouse cerebellum during postnatal development.

GRIN2A GRIN2B GRIN2C

1.99e-07412938595214
Pubmed

Phenotypic characterization of orofacial movement topography in mutants with disruption of amino acid mechanisms: glutamate N2A/B/D [GluRε1/2/4] subtypes and the GABA synthesizing enzyme GAD65.

GRIN2A GRIN2B GRIN2D

1.99e-074129323892010
Pubmed

Immunohistochemical localization of N-methyl-D-aspartate receptor subunits in the adult murine hippocampal formation: evidence for a unique role of the NR2D subunit.

GRIN2A GRIN2B GRIN2D

1.99e-074129312191494
Pubmed

Chronic ethanol treatment produces a selective upregulation of the NMDA receptor subunit gene expression in mammalian cultured cortical neurons.

GRIN2A GRIN2B GRIN2C

1.99e-07412938965641
Pubmed

Guanylate-binding protein-5 is involved in inflammasome activation by bacterial DNA but only the cooperation of multiple GBPs accounts for control of Brucella abortus infection.

GBP1 GBP2 GBP5

1.99e-074129338404575
Pubmed

NMDA receptor upregulation: molecular studies in cultured mouse cortical neurons after chronic antagonist exposure.

GRIN2A GRIN2B GRIN2C

1.99e-07412938601798
Pubmed

The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.

RASGRF1 GRIN2A GRIN2B GRIN2D

2.39e-0715129414622581
Pubmed

Neurotoxicity of human immunodeficiency virus-1: viral proteins and axonal transport.

GRIN2A GRIN2B GRIN2C GRIN2D

2.39e-0715129421948112
Pubmed

Neuronal interleukin-16 (NIL-16): a dual function PDZ domain protein.

GRIN2A GRIN2B GRIN2C GRIN2D

2.39e-0715129410479680
Pubmed

Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.

DRD5 HTR4 GRIN2A GRIN2B GRIN2C GRIN2D HRH3

3.07e-07118129719156168
Pubmed

Chemokine co-receptor CCR5/CXCR4-dependent modulation of Kv2.1 channel confers acute neuroprotection to HIV-1 glycoprotein gp120 exposure.

GRIN2A GRIN2B GRIN2C GRIN2D

4.14e-0717129424086760
Pubmed

Modified N-methyl-D-aspartate receptor subunit expression emerges in reeler Purkinje cells after accomplishment of the adult wild-type expression.

GRIN2A GRIN2B GRIN2C

4.96e-07512939004271
Pubmed

Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic.

CLTCL1 PICALM SNAP91

4.96e-075129310436022
Pubmed

Fyn kinase-mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain.

GRIN2A GRIN2B GRIN2D

4.96e-075129316190898
Pubmed

Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection.

GBP7 GBP1 GBP2

4.96e-075129331964735
Pubmed

Gene structure and chromosomal localization of the mouse NMDA receptor channel subunits.

GRIN2A GRIN2B GRIN2C GRIN2D

5.31e-071812949011744
Pubmed

Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.

GRIN2A GRIN2B GRIN2C GRIN2D TACR1 GABRA6

5.99e-0781129622723691
Pubmed

Tulp3 Is a Ciliary Trafficking Gene that Regulates Polycystic Kidney Disease.

ADCY3 PKD1 PKD2

9.89e-076129330799240
Pubmed

The human immunodeficiency virus coat protein gp120 promotes forward trafficking and surface clustering of NMDA receptors in membrane microdomains.

GRIN2A GRIN2B GRIN2C GRIN2D

1.03e-0621129422114277
Pubmed

HIV-1 Tat causes apoptotic death and calcium homeostasis alterations in rat neurons.

GRIN2A GRIN2B GRIN2D

1.73e-067129311606043
Pubmed

Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site.

GRIN2A GRIN2B GRIN2D

1.73e-067129312775422
Pubmed

Long-term potentiation in the CA1 hippocampus induced by NR2A subunit-containing NMDA glutamate receptors is mediated by Ras-GRF2/Erk map kinase signaling.

RASGRF1 GRIN2A GRIN2B

1.73e-067129320661302
Cytoband1p22.2

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

1.57e-102812961p22.2
CytobandEnsembl 112 genes in cytogenetic band chr1p22

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

2.66e-061371296chr1p22
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2A GRIN2B GRIN2C GRIN2D

1.90e-0878941201
GeneFamilyG protein-coupled receptors, Class A orphans

MAS1L MAS1 MRGPRX1 GPR75 MRGPRX3

4.11e-0578895262
GeneFamilySerpin peptidase inhibitors

SERPINA3 SERPINA12 SERPINA9

7.94e-0437893739
GeneFamilyATP binding cassette subfamily A

ABCA13 ABCA10

2.10e-0314892805
GeneFamilyParkinson disease associated genes

LRRK2 ATP13A2

2.75e-0316892672
CoexpressionHOWARD_B_CELL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

GBP1 GBP2 GBP4 GBP5

5.23e-07141284M41166
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_8_PRECICTIVE_ICB_RESPONSE

SERPINA3 GBP6 ATP8B4 GBP1 GBP2 MS4A4A ICOS PTPRC GBP5

6.38e-072001289MM17082
CoexpressionSEKI_INFLAMMATORY_RESPONSE_LPS_UP

SERPINA3 GBP6 GBP7 GBP1 GBP2 GBP4

4.40e-06871286MM1253
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_14_PRECICTIVE_ICB_RESPONSE

GBP7 GBP1 GBP2 CSMD3 PTGER4 SLC12A1 GBP4 SLC4A4

6.07e-061981288MM17083
CoexpressionMIKKELSEN_MCV6_LCP_WITH_H3K27ME3

TMPRSS13 LYZL6 TG TAS2R40

1.01e-05281284M1957
CoexpressionMATSUMIYA_PBMC_MODIFIED_VACCINIA_ANKARA_VACCINE_AGE_4_6MO_BCG_PRIMED_28DY_UP

GBP1 GBP4 GBP5

1.33e-05101283M41004
CoexpressionMIKKELSEN_MCV6_LCP_WITH_H3K27ME3

TMPRSS13 LYZL6 TG TAS2R40

1.35e-05301284MM835
CoexpressionSOBOLEV_PBMC_PANDEMRIX_AGE_18_64YO_7DY_DN

GBP1 GBP2 GBP4 GBP5

1.99e-05331284M41194
CoexpressionICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP

SERPINA3 GBP7 GBP1 GBP2 MS4A4A PTPRC GBP4

2.61e-051761287MM1048
CoexpressionGSE43863_NAIVE_VS_MEMORY_TH1_CD4_TCELL_D150_LCMV_UP

MAS1 GBP1 GBP2 GBP5 KIF28P TAS2R40 SERPINA9

4.11e-051891287M9722
CoexpressionWATANABE_ULCERATIVE_COLITIS_WITH_CANCER_DN

GBP1 GBP4 GBP5

4.96e-05151283M15662
CoexpressionHOWARD_T_CELL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

GBP1 GBP2 GBP4 GBP5

5.26e-05421284M41024
CoexpressionGSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_DN

GBP6 GBP7 LYPLAL1 GBP2 TG GBP4 PKD2

5.70e-051991287M7341
CoexpressionGSE22589_HEALTHY_VS_HIV_INFECTED_DC_DN

GBP6 GBP7 LRRK2 GBP2 CFAP54 GBP4 TRAPPC14

5.88e-052001287M7807
CoexpressionICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP

SERPINA3 GBP7 GBP1 GBP2 MS4A4A GBP4

6.12e-051381286MM1047
CoexpressionTABULA_MURIS_SENIS_LIMB_MUSCLE_ENDOTHELIAL_CELL_AGEING

GBP6 GBP7 GBP1 GBP2 GBP4 GBP5

8.05e-051451286MM3744
CoexpressionNIKOLSKY_MUTATED_AND_AMPLIFIED_IN_BREAST_CANCER

GRIN2C CSMD3 TG CLPTM1L LPO

9.95e-05941285M18108
CoexpressionZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_OVERLAP_UP

GBP6 GBP7 GBP1 GBP2 GBP4

1.21e-04981285MM460
CoexpressionZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_RENCA_UP

GBP6 GBP7 GBP1 GBP2 GBP4

1.33e-041001285MM458
CoexpressionRUAN_RESPONSE_TO_TNF_UP

SERPINA3 GBP1 GBP2

1.42e-04211283MM651
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#1_top-relative-expression-ranked_1000

HTR4 GBP7 ZBTB4 GBP1 ABCC9 SLC52A3 GBP4 AGTR1

3.35e-071211168gudmap_developingLowerUrinaryTract_P1_ureter_1000_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#3_top-relative-expression-ranked_500

HTR4 GBP7 ZBTB4 GBP1 ABCC9 GBP4 SLITRK6

1.56e-061031167gudmap_developingLowerUrinaryTract_adult_bladder_500_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_top-relative-expression-ranked_1000

SERPINA3 TBX4 HTR4 TMPRSS13 GBP7 RASGRF1 ZBTB4 GBP1 ABCC9 CSMD3 SLC52A3 SLC12A1 TMEM184A PLXDC2 PCDH11X SLITRK6

5.58e-0678311616gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_1000
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_500

GBP6 GBP7 GBP1 GBP2 PTPRC GBP4 HMCN1 PLXDC2 ACKR3 AGTR1 SLC4A4

1.49e-0540811611gudmap_kidney_adult_RenalCapsule_500
CoexpressionAtlasDevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#3_top-relative-expression-ranked_1000

TBX4 HTR4 GBP7 ZBTB4 GBP1 ABCC9 GBP4 SLITRK6

1.90e-052081168gudmap_developingLowerUrinaryTract_adult_bladder_1000_k3
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4

REV3L PLXDC2 ASXL3 SLITRK6 ITIH6 MUC4

2.42e-051051166Facebase_RNAseq_e10.5_Medial Nasal Eminence_500_K4
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_200

GBP6 GBP7 GBP1 ABCC9 PTGER4 GBP4 AGTR1

3.73e-051671167gudmap_kidney_adult_Mesangium_Meis_200
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_top-relative-expression-ranked_500

SERPINA3 TMPRSS13 RASGRF1 GBP1 ABCC9 CSMD3 SLC52A3 SLC12A1 TMEM184A SLITRK6

5.29e-0538711610gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_500
CoexpressionAtlaskidney_adult_CortVasc_Tie2_k-means-cluster#2_top-relative-expression-ranked_500

GBP6 GBP7 GBP4 GBP5 AGTR1

6.05e-05761165gudmap_kidney_adult_CortVasc_Tie2_k2_500
CoexpressionAtlaskidney_adult_CortVasc_Tie2_k-means-cluster#4_top-relative-expression-ranked_100

GBP6 GBP7 GBP1

8.45e-05161163gudmap_kidney_adult_CortVasc_Tie2_k4_100
CoexpressionAtlaskidney_adult_Mesangium_Meis_k-means-cluster#1_top-relative-expression-ranked_200

GBP6 GBP7 GBP1 GBP4

1.06e-04451164gudmap_kidney_adult_Mesangium_Meis_k1_200
CoexpressionAtlaskidney_adult_GlomCapSys_Tie2_k-means-cluster#3_top-relative-expression-ranked_500

GBP6 GBP7 GBP1 GBP4 GBP5

1.15e-04871165gudmap_kidney_adult_GlomCapSys_Tie2_k3_500
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#2_top-relative-expression-ranked_200

ABCA13 REV3L TMEM33 SLC12A1 SLC4A4

1.22e-04881165gudmap_developingKidney_e15.5_200_k2
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_500

GBP6 GBP7 GBP1 ABCC9 PTGER4 PICALM GBP4 GBP5 PLXDC2 AGTR1

1.24e-0442911610gudmap_kidney_adult_Mesangium_Meis_500
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#4_top-relative-expression-ranked_500

HTR4 GBP7 GBP1 ABCC9

1.26e-04471164gudmap_developingLowerUrinaryTract_P1_ureter_500_k4
CoexpressionAtlaskidney_adult_RenCorpuscGlomer_k-means-cluster#4_top-relative-expression-ranked_1000

GBP6 GBP7 PTGER4 PICALM GBP4 AGTR1

1.64e-041481166gudmap_kidney_adult_RenCorpuscGlomer_k4_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_adult_bladder_emap-29457_top-relative-expression-ranked_500

SERPINA3 HTR4 TMPRSS13 GBP7 ZBTB4 GBP1 ABCC9 GBP4 SLITRK6

2.33e-043781169gudmap_developingLowerUrinaryTract_adult_bladder_500
CoexpressionAtlaskidney_adult_CortVasc_Tie2_top-relative-expression-ranked_200

GBP6 GBP7 GBP1 SLC12A1 GBP5 SLC4A4

2.67e-041621166gudmap_kidney_adult_CortVasc_Tie2_200
CoexpressionAtlaskidney_adult_Mesangium_Meis_k-means-cluster#4_top-relative-expression-ranked_100

GBP6 GBP7

2.93e-0451162gudmap_kidney_adult_Mesangium_Meis_k4_100
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_1000

GBP6 GBP7 GBP1 GBP2 CCNG1 PTPRC GBP4 HMCN1 GBP5 PLXDC2 ACKR3 AGTR1 SLC4A4

3.31e-0477811613gudmap_kidney_adult_RenalCapsule_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500

REV3L STK11IP TMEM184A PLXDC2 ASXL3 ELAPOR1 MROH7 SLITRK6 ITIH6 MUC4

3.48e-0448811610Facebase_RNAseq_e10.5_Medial Nasal Eminence_500
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_interstitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GBP7 FPR3 GBP1 GBP2 OLR1 MS4A4A PTPRC GBP4 GBP5

7.01e-0919912994b6d49b96bfcd6604b082bab620ae03276520885
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 ABCA13 GRIN2B CSMD3 HMCN1 ASXL3 PCDH11X SLC4A4

6.72e-0818412982cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 ABCA13 GRIN2B CSMD3 HMCN1 ASXL3 PCDH11X SLC4A4

6.72e-081841298ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 ABCA13 GRIN2B CSMD3 HMCN1 ASXL3 PCDH11X SLC4A4

6.72e-0818412982b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellBAL-Mild-cDC_1|Mild / Compartment, Disease Groups and Clusters

FPR3 GBP1 GBP2 OLR1 MS4A4A GBP4 GBP5 PLXDC2

1.23e-071991298c55181bdec8952b54198f0d4c9c5c84265b16572
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GBP7 ABCA13 GBP1 GBP2 RALGAPA2 GBP4 MRGPRX3 MUC4

1.28e-0720012980f6620a5baace704518d42fa2f3f90751240f7dd
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GBP6 NUP210L GBP2 ICOS PTPRC GBP4 DYNLT5

4.76e-071621297adf545cf9357556e2ce7affed01c2f6a24b0581d
ToppCellNS-moderate-d_07-13-Myeloid-Monocyte-derived_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GBP7 FPR3 GBP1 MS4A4A PTPRC GBP4 GBP5

1.04e-061821297e03e995e5fd14fc6a7559b83c0ca4e7ccc8e3d0f
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

ATP8B4 MAS1L ABCC9 REV3L MED13L HMCN1 PLXDC2

1.12e-06184129767164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAG1 GRIN2B GRIN2C CSMD3 NLGN3 ASB5 HRH3

1.20e-061861297bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCellNS-moderate-d_0-4-Myeloid-Non-resident_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FPR3 GBP1 GBP2 OLR1 MS4A4A PTPRC GBP5

1.25e-061871297fcc32dbc9c5ae6176f154715a3e73aa32d78ad64
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TBX4 GBP1 CSMD3 PHEX HMCN1 PLXDC2 AGTR1

1.34e-061891297203c80030df08ae112f9ae4043709f455d87ce89
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TMPRSS13 ABCA13 URB1 ASXL3 ELAPOR1 SLC4A4 MUC4

1.59e-061941297e0228f593c3493175962a4817500d4337ddc4e88
ToppCellCOVID_non-vent-Myeloid-Monocytic-CD16+_Monocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

FPR3 GBP1 GBP2 PTGER4 MS4A4A GBP4 GBP5

1.59e-0619412971b4a17d58793e8889484fe592dce8ee1e8fe77a9
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FPR3 PTGER4 PICALM OLR1 MS4A4A PTPRC PLXDC2

1.59e-0619412975022c85ad3b137dae4b9ff11f9c23bb3bf4c0f5a
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

ATP8B4 FPR3 OLR1 MS4A4A PTPRC GBP5 PLXDC2

1.65e-061951297148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ATP8B4 FPR3 OLR1 MS4A4A PTPRC GBP5 PLXDC2

1.71e-0619612977026c1fc33425e5476063d17c79e4b79356a9e01
ToppCellBL|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LRRK2 GBP1 GBP2 PICALM PTPRC GBP4 GBP5

1.77e-0619712971acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCellBAL-Severe-cDC_1|Severe / Compartment, Disease Groups and Clusters

FPR3 GBP1 GBP2 PTGER4 PTPRC GBP4 GBP5

1.89e-0619912979f5750212b887f92761ade33fc6e108cd5275297
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ATP8B4 MED13L PICALM OLR1 BROX PTPRC PLXDC2

1.95e-062001297a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ATP8B4 MED13L PICALM OLR1 BROX PTPRC PLXDC2

1.95e-062001297dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRIN2C SLC12A1 SLCO1C1 RANBP3L CYP2G1P GPR75 MROH7

1.95e-0620012977a8160e6477708f22e48c609bf8f43f3715dcb03
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ATP8B4 MED13L PICALM OLR1 BROX PTPRC PLXDC2

1.95e-0620012973bba5219453322198e8fdb0921d5f8c403598751
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ATP8B4 MED13L PICALM OLR1 BROX PTPRC PLXDC2

1.95e-06200129721bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ATP8B4 MED13L PICALM OLR1 BROX PTPRC PLXDC2

1.95e-062001297a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

ATP8B4 MED13L PICALM OLR1 BROX PTPRC PLXDC2

1.95e-06200129733036d21c1c82109284473a515c4f890b33fdd5c
ToppCellBronchus_Control_(B.)-Immune-TX-DCs|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ATP8B4 FPR3 PTGER4 OLR1 MS4A4A PTPRC PLXDC2

1.95e-062001297e0beacb88bbdc353a3e883171613027feafcf1ef
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TBX4 LCT TG SLC52A3 HMCN1

2.63e-067512953167beedef7304697e9577270cdeacfc9743cee1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TBX4 LCT TG SLC52A3 HMCN1

2.63e-0675129570c346f92a9ac7e33fc1b9dee1dca0bf9ae0a38c
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TBX4 LCT TG SLC52A3 HMCN1

2.63e-0675129526d6e54ed0a6c3ff57f6269c460177bc7b8bf979
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR4 ABCA13 LYZL6 GRIN2B CSMD3 SNAP91

4.15e-06145129696712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellMS-CD4-antiviral_CD4|MS / Condition, Cell_class and T cell subcluster

HTR4 GBP1 GBP2 TG GBP4 GBP5

5.44e-061521296b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLTCL1 HTR4 SPEG ADCY3 PKD1 SLC4A4

6.55e-061571296f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA13 GBP1 GRIN2B CSMD3 SERPINA12 SNAP91

7.84e-061621296bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

GBP1 ABCC9 CSMD3 ATP13A2 GBP4 GBP5

8.41e-061641296362c16ed7fb37bf16601fd5e059d3f3e2ed692b4
ToppCellClub_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

SERPINA3 PHEX TMEM184A ELAPOR1 TACR1 MUC4

9.32e-061671296dbdaaeb3bd9139cb008d9fe24ec031fc5628f136
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FPR3 LYZL6 OLR1 PTPRC GBP5 ASB5

9.98e-061691296c3d410a5e98000ba872141b62e17ef4ed3d1a8eb
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP6 TMPRSS13 RASGRF1 ICOS GPR75 ELAPOR1

1.07e-0517112966f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP6 TMPRSS13 RASGRF1 ICOS GPR75 ELAPOR1

1.07e-051711296ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP6 GBP7 GBP2 GBP4 GBP5 EVA1A

1.30e-051771296ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP6 GBP7 GBP2 GBP4 GBP5 EVA1A

1.30e-051771296f471f7747d6e8db7546899019af9508f48a14f89
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP6 GBP7 GBP2 GBP4 GBP5 EVA1A

1.30e-051771296cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP6 GBP7 NUP210L GBP2 GBP4 GBP5

1.34e-05178129601dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellControl-Myeloid-Dendritic_cells|Control / group, cell type (main and fine annotations)

ATP8B4 FPR3 PICALM MS4A4A PTPRC PLXDC2

1.43e-05180129625ad95c3c30e3b82abe93bd77ba003f5c2241f7c
ToppCellControl-APC-like-Dendritic_cells|Control / group, cell type (main and fine annotations)

ATP8B4 FPR3 PICALM MS4A4A PTPRC PLXDC2

1.57e-0518312968f9c8e2436f18ea7c265b08e4e149e19cb513a16
ToppCellControl-APC-like|Control / group, cell type (main and fine annotations)

ATP8B4 FPR3 PICALM MS4A4A PTPRC PLXDC2

1.57e-051831296c313ac72cc9fa1583456d452393f61f0a4ca33a8
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC3_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATP8B4 TG ICOS PTPRC GBP5 ELAPOR1

1.62e-0518412963e9d75af578297950e469f23fb2d28393a2feef8
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TBX4 ABCC9 ADCY3 AGTR1 DYNLT5 SLC4A4

1.62e-051841296327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Thalamus / BrainAtlas - Mouse McCarroll V32

TBX4 SLC52A3 SLCO1C1 GBP4 GBP5

1.65e-0510912954e4a884b8979f4ff8b232c1581ea78884dda29ed
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

USP24 OLR1 ABCA10 HMCN1 RANBP3L LRBA

1.83e-051881296bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

USP24 OLR1 ABCA10 HMCN1 RANBP3L LRBA

1.83e-051881296eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP24 ABCA10 SLC12A1 HMCN1 RANBP3L LRBA

1.88e-051891296f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellPCW_13-14-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC3_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ATP8B4 GBP2 ICOS PTPRC GBP5 ELAPOR1

1.88e-05189129678dcda09109a5cfb04ba069f16ec80987b3ad432
ToppCellCOVID-19-Heart-Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

ATP8B4 FPR3 MS4A4A PTPRC PLXDC2 SLC38A6

1.88e-0518912962586f4088721c5debec86c2b211b739fd33713eb
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

RASGRF1 GRIN2A GRIN2B CELSR3 ELAPOR1 HRH3

1.94e-051901296416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellhuman_hepatoblastoma-Inflammatory_Monocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

ATP8B4 FPR3 LRRK2 MS4A4A PTPRC PLXDC2

2.00e-0519112963b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCellControl-Myeloid|Control / group, cell type (main and fine annotations)

FPR3 OLR1 TG MS4A4A PTPRC PLXDC2

2.00e-0519112969c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

FPR3 OLR1 MS4A4A PTPRC PLXDC2 SLC38A6

2.06e-051921296bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCellNS-critical-d_07-13-Myeloid-Monocyte-derived_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FPR3 GBP1 GBP2 MS4A4A GBP4 GBP5

2.12e-0519312960dd83b21e164147abfd511a927615c40a28781a2
ToppCellLeuk-UTI|World / Disease, Lineage and Cell Type

GBP7 GBP1 GBP2 MS4A4A GBP4 GBP5

2.12e-05193129626119a0b5d7684022fd16b8b73a0ef5a7d70f3d1
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FPR3 PTGER4 OLR1 MS4A4A PTPRC PLXDC2

2.18e-051941296ce0486ce43748ffe486f08fdddd1f6acbfcc6b0e
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FPR3 GBP1 GBP2 MS4A4A GBP4 GBP5

2.18e-051941296e36d1fd141bdcbd9ed66a33de6cdfde77189a0c1
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

ATP8B4 FPR3 TG MS4A4A PTPRC PLXDC2

2.18e-051941296ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR4 RASGRF1 GRIN2A GRIN2B SNAP91 ELAPOR1

2.24e-051951296ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCellhuman_hepatoblastoma-Inflammatory_Monocytes|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

ATP8B4 FPR3 LRRK2 MS4A4A PTPRC PLXDC2

2.24e-051951296ba7f85e5307d96ac5ad7c952f8d094db9ca1790c
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|COVID-19 / Condition, Lineage and Cell class

ABCA13 ELAPOR1 TACR1 SLITRK6 SLC4A4 MUC4

2.31e-051961296dd32046067d93b9484cfbf1d7826a436a3d9f0e9
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FPR3 PTGER4 OLR1 MS4A4A PTPRC PLXDC2

2.31e-0519612965fe6534af65d43eeacd4b031310242b4f706008b
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ATP8B4 FPR3 OLR1 MS4A4A PTPRC PLXDC2

2.38e-051971296e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ATP8B4 FPR3 GRIN2D STK11IP MS4A4A PLXDC2

2.38e-051971296e2983ae16c72371fbf0e5c123de9f4d900724e5e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FPR3 PTGER4 OLR1 MS4A4A PTPRC PLXDC2

2.38e-051971296f807d8cd377ee58c02be7f71b39cd227f6b4f5df
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTGER4 PICALM OLR1 MS4A4A PTPRC PLXDC2

2.44e-051981296b50074297184bcc044d06e20bb1d3733b9bd8df7
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ATP8B4 ABCA13 TMEM184A ELAPOR1 TACR1 MUC4

2.44e-051981296af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellMacrophages-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

FPR3 GBP1 GBP2 PTPRC GBP5 PLXDC2

2.44e-0519812968517386a2f0d14c7d5fc6283e4e16b94d7c5732a
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GBP7 FPR3 OLR1 MS4A4A PTPRC PLXDC2

2.51e-05199129698c0d57c247d39bc771d81f4387f8dd01222628e
ToppCellproximal-Epithelial-Mucous-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINA3 URB1 ELAPOR1 TACR1 SLC4A4 MUC4

2.51e-051991296baac580484124b7c36717b607adcf2cb446e631d
ToppCellproximal-Epithelial-Mucous|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINA3 URB1 ELAPOR1 TACR1 SLC4A4 MUC4

2.51e-05199129615ba36fa6ad73d0e959e42f18d7acbc14e310dc9
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GBP1 GBP2 MS4A4A PTPRC GBP4 GBP5

2.51e-051991296841338719d042247966867ac608146395eb8c4d9
ToppCellproximal-3-Epithelial-Mucous|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINA3 URB1 ELAPOR1 TACR1 SLC4A4 MUC4

2.51e-0519912963018378860de084662be0cc46fce421db3bb9ec9
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GBP7 FPR3 OLR1 MS4A4A PTPRC PLXDC2

2.51e-051991296b818d46a39c8782188d82dc8931b8eec9d549dd1
ToppCellParenchymal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ATP8B4 FPR3 OLR1 MS4A4A PTPRC PLXDC2

2.51e-0519912967ee2805fd9143eba11bf6832267b62189683608b
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T|COVID-19_Mild / Disease, condition lineage and cell class

USP24 GBP1 GBP2 ICOS GBP4 LRBA

2.51e-051991296f307d4887b28cf60a591439e278fd668409cb104
ToppCellCOVID-19_Severe-Neu_1|World / 5 Neutrophil clusters in COVID-19 patients

LRRK2 GBP2 PICALM PTPRC GBP4 GBP5

2.51e-051991296e4d8bf016fd95a440e30014a75587e097e90cfad
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBX4 ABCA10 PHEX HMCN1 PLXDC2 RANBP3L

2.59e-052001296e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

HTR4 NLGN3 PKD2 PCDH11X SLITRK6 SLC4A4

2.59e-052001296a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellBronchial-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP54 PLXDC2 RANBP3L PKD2 ITIH6 ADGRA3

2.59e-052001296b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCellParenchyma_COVID-19-Epithelial-TX-Club|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ABCA13 ELAPOR1 TACR1 SLITRK6 SLC4A4 MUC4

2.59e-05200129685f946dd3831acf3488c87efba96689cc2667c3a
ToppCellBronchial-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ATP8B4 FPR3 OLR1 MS4A4A PTPRC PLXDC2

2.59e-0520012962f5b71e55c2de0e77fdae6667eb57f333acc6cd1
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 ELAPOR1 TACR1 SLITRK6 SLC4A4 MUC4

2.59e-0520012968a44a4f7ea9358f2194a490e79601c98ff7fdcb0
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA13 ELAPOR1 TACR1 SLITRK6 SLC4A4 MUC4

2.59e-05200129630d428510c68da96c7c8cfd472f449ebb9631132
ToppCellBronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP54 PLXDC2 RANBP3L PKD2 ITIH6 ADGRA3

2.59e-0520012967c673ad0ea503ebd196579684d25d5f9e6a41030
ToppCellEndothelial-Endothelial-F|Endothelial / shred on cell class and cell subclass (v4)

GBP6 GBP7 GBP2 GBP4 GBP5

2.84e-0512212952cb8bb63c69aed4d4504b9d97219b8707666f950
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pou6f2-Inhibitory_Neuron.Gad1Gad2.Pou6f2-Pax6_(Zona_incerta_(ZI))|Thalamus / BrainAtlas - Mouse McCarroll V32

MFSD2B LCT SERPINA12 SERPINA9

3.16e-0562129402f0398e18bd61fbfa03bce71ae77e106181abee
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pou6f2-Inhibitory_Neuron.Gad1Gad2.Pou6f2-Pax6_(Zona_incerta_(ZI))-|Thalamus / BrainAtlas - Mouse McCarroll V32

MFSD2B LCT SERPINA12 SERPINA9

3.16e-056212948fdbced7a2baa1bfb5b1e204128234424a872fe6
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pou6f2|Thalamus / BrainAtlas - Mouse McCarroll V32

MFSD2B LCT SERPINA12 SERPINA9

3.16e-05621294ff68e007b8b2af4c7fb09139aed92e86907a05da
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CFAP54 ASB5 LPO ADGRA3 KCNH5

4.78e-05136129527a41463e6f16deb5b1d4f17fefded9959038c07
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP54 ASB5 LPO ADGRA3 KCNH5

4.78e-05136129588b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCellEndothelial-F|World / shred on cell class and cell subclass (v4)

GBP6 GBP7 GBP2 GBP4 GBP5

5.30e-05139129532d3c5d35e6c4205711c3500d736fd108443e6b4
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK|Hippocampus / BrainAtlas - Mouse McCarroll V32

TBX4 SLC52A3 GBP4 HMCN1 GBP5

5.30e-05139129534398a6f21a1e670497655a7bb7f3cde9e117560
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

TBX4 SLC52A3 GBP4 HMCN1 GBP5

5.30e-051391295450c4152c9fe4ec503271bb3cf93739918c59509
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNF169 FPR3 GXYLT1 OLR1 ZNF404

5.48e-051401295276b3fa924176426efb31112ed4d355407f0b218
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

GBP1 GBP2 GBP4 GBP5

1.46e-0450584GAVISH_3CA_METAPROGRAM_MACROPHAGES_INTERFERON
ComputationalGenes in the cancer module 146.

HTR4 FPR3 OR2F1 GPR75 AGTR1

2.14e-04102585MODULE_146
Drug5-(alpha-methyl-4-bromobenzylamino)phosphonomethyl-1,4-dihydroquinoxaline-2,3-dione

GRIN2A GRIN2B GRIN2C GRIN2D

4.90e-0951294ctd:C498554
Drug2-Aminoadipic Acid

GRIN2A GRIN2B GRIN2C GRIN2D

4.90e-0951294ctd:D015074
Drug(2S*,3R*)-1-(biphenyl-4-carbonyl)piperazine-2,3-dicarboxylic acid

GRIN2A GRIN2B GRIN2C GRIN2D

4.90e-0951294ctd:C491996
DrugSDZ EAA 494

GRIN2A GRIN2B GRIN2C GRIN2D

4.90e-0951294ctd:C065286
Drugnorbiotin

TBX4 DRD5 GRIN2A GRIN2B GRIN2C GRIN2D TACR1 HRH3

7.53e-09721298CID000446903
DrugSKF 38393

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D ADCY3 CELSR3 LRBA HRH3

1.30e-081101299CID000001242
DrugMeperidine

GRIN2A GRIN2B GRIN2C GRIN2D

1.46e-0861294DB00454
Drug1,5-(diethylamino)piperidine

GRIN2A GRIN2B GRIN2C GRIN2D

1.46e-0861294CID000004025
DrugNaphthols

GRIN2A GRIN2B GRIN2C GRIN2D

1.46e-0861294ctd:D009284
DrugSCH 23390

DRD5 HTR4 GRIN2A GRIN2B GRIN2C GRIN2D ADCY3 LRBA HRH3

2.08e-081161299CID000005018
DrugDPCPX

DRD5 CLTCL1 GRIN2A GRIN2B GRIN2C GRIN2D ADCY3 LRBA SLC4A4

2.24e-081171299CID000001329
Drug3,4,7,8-tetrahydroquinoline

GRIN2A GRIN2B GRIN2C GRIN2D HRH3

2.24e-08161295CID000094356
DrugNSC-673323

SERPINA3 GRIN2A GRIN2B GRIN2C GRIN2D TG

2.36e-08321296CID000384101
Drug7-Cl-Thio-Kyna

GRIN2A GRIN2B GRIN2C GRIN2D TACR1

3.16e-08171295CID003035668
DrugTenocyclidine

GRIN2A GRIN2B GRIN2C GRIN2D

3.40e-0871294DB01520
Drugtetrazol-5-yl)glycine

GRIN2A GRIN2B GRIN2C GRIN2D

3.40e-0871294CID000126383
Drug3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid

GRIN2A GRIN2B GRIN2C GRIN2D

3.40e-0871294ctd:C050592
Drughomoquinolinate

GRIN2A GRIN2B GRIN2C GRIN2D

3.40e-0871294CID003080554
DrugS)-piperazine-2-carboxylic acid

GRIN2A GRIN2B GRIN2C GRIN2D

3.40e-0871294CID001502069
DrugMNQX

GRIN2A GRIN2B GRIN2C GRIN2D TACR1

4.36e-08181295CID000130818
DrugNBQX

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D SNAP91 TACR1 GABRA6

4.48e-08901298CID003272523
Drugarcaine

GRIN2A GRIN2B GRIN2C GRIN2D TACR1

5.89e-08191295CID000002227
DrugL-687,414

GRIN2A GRIN2B GRIN2C GRIN2D

6.76e-0881294CID000125556
Drug6-chloroquinoxaline-2,3-diol

GRIN2A GRIN2B GRIN2C GRIN2D

6.76e-0881294CID000081143
DrugES-242-1

GRIN2A GRIN2B GRIN2C GRIN2D

6.76e-0881294CID000131976
DrugSDZ 220-581

GRIN2A GRIN2B GRIN2C GRIN2D

6.76e-0881294CID000128019
Drug3alpha5betaHS

GRIN2A GRIN2B GRIN2C GRIN2D

6.76e-0881294CID000165024
Drugneramexane

GRIN2A GRIN2B GRIN2C GRIN2D

6.76e-0881294CID006433106
Drugpiperazine-2,3-dicarboxylic acid

GRIN2A GRIN2B GRIN2C GRIN2D

6.76e-0881294CID000280973
Drugsulpiride

DRD5 HTR4 ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D ADCY3

7.45e-08961298CID000005355
DrugPhenanthrenes

GRIN2A GRIN2B GRIN2C GRIN2D

1.21e-0791294ctd:D010616
Drugbaclofen

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D ADCY3 PKD1 PKD2 TACR1 GABRA6

1.41e-0719112910CID000002284
Drugloperamide

HTR4 GRIN2A GRIN2B GRIN2C GRIN2D PKD1 PKD2 TACR1

1.50e-071051298CID000003954
Drugpentanol

GRIN2A GRIN2B GRIN2C GRIN2D ADCY3

1.67e-07231295CID000006276
Drugconotoxin GV

GRIN2A GRIN2B GRIN2C

1.78e-0731293ctd:C055407
DrugEAB 515

GRIN2A GRIN2B GRIN2C GRIN2D

3.15e-07111294CID000159489
Drug5-phosphonopentanoic acid

GRIN2A GRIN2B GRIN2C GRIN2D

3.15e-07111294CID002773807
Drugoxiracetam

GRIN2A GRIN2B GRIN2C GRIN2D

3.15e-07111294CID000004626
Drugo-difluorobenzene

GRIN2A GRIN2B GRIN2C GRIN2D

3.15e-07111294CID000009706
DrugPiperazines

HTR4 GRIN2B GRIN2C GRIN2D

3.15e-07111294ctd:D010879
DrugAC1NQH9B

CLTCL1 GRIN2A GRIN2B GRIN2C GRIN2D

3.23e-07261295CID005221504
Drug8-OH-DPAT

DRD5 HTR4 ABCC9 GRIN2A GRIN2B GRIN2C GRIN2D ADCY3

3.47e-071171298CID000001220
Drug2-chloropropionate

GRIN2A GRIN2B GRIN2C GRIN2D ZBTB21

3.95e-07271295CID000011734
DrugCI-1041

GRIN2A GRIN2B GRIN2C GRIN2D

4.70e-07121294CID000156328
Drugtenocyclidine

GRIN2A GRIN2B GRIN2C GRIN2D

4.70e-07121294CID000062751
Drugchlormethiazole

GRIN2A GRIN2B GRIN2C GRIN2D GABRA6

4.78e-07281295CID000010783
Drugpropanol

FTSJ1 GRIN2A GRIN2B GRIN2C GRIN2D ADCY3

5.43e-07531296CID000001031
Drug1,10-diaminodecane

GRIN2A GRIN2B GRIN2C GRIN2D

6.76e-07131294CID000001317
DrugAgmatine

GRIN2A GRIN2B GRIN2C GRIN2D

6.76e-07131294ctd:D000376
DrugAC1L63MU

FPR3 GRIN2A GRIN2B GRIN2C GRIN2D PTGER4 ADCY3 TG SLC12A1 AGTR1 LRBA HRH3

6.89e-0734712912CID000285703
Drugpiperidine

HTR4 FTSJ1 GRIN2A GRIN2B GRIN2C GRIN2D TACR1 HRH3

7.77e-071301298CID000008082
DrugAC1L1CLB

HTR4 GRIN2A GRIN2B GRIN2C GRIN2D TACR1 LRBA

9.35e-07921297CID000001951
Drugremacemide

GRIN2A GRIN2B GRIN2C GRIN2D

9.42e-07141294CID000060510
Drugpentamidine

SERPINA3 GRIN2A GRIN2B GRIN2C GRIN2D

1.13e-06331295CID000004735
DrugBMY 14802

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D

1.13e-06331295CID000108046
Drug1,3-di-o-tolylguanidine

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D TG

1.27e-06611296CID000007333
DrugACEA-1011

GRIN2A GRIN2B GRIN2C GRIN2D

1.28e-06151294CID000127872
Drugthiokynurenic acid

GRIN2A GRIN2B GRIN2C GRIN2D

1.28e-06151294CID003035667
DrugLY 171555

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D ADCY3 LRBA HRH3

1.52e-061421298CID000001257
DrugAP-7

GRIN2A GRIN2B GRIN2C GRIN2D SNAP91 GABRA6

1.53e-06631296CID000003122
Drugbiotinyl-L-lysine

GRIN2A GRIN2B GRIN2C GRIN2D LPO TACR1 GABRA6

1.54e-06991297CID000083814
Drugargiopine

GRIN2A GRIN2B GRIN2C GRIN2D

1.70e-06161294CID000122294
Drugmetaphit

GRIN2A GRIN2B GRIN2C GRIN2D

1.70e-06161294CID000114745
DrugLY233536

GRIN2A GRIN2B GRIN2C GRIN2D

1.70e-06161294CID000126239
DrugC6H12NO5P

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D

1.77e-06361295CID000104962
Drug3-bromo-7-nitroindazole

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D

1.77e-06361295CID000001649
Drugscopolamine

DRD5 HTR4 GRIN2A GRIN2B GRIN2C GRIN2D TG TACR1 HRH3

2.15e-062001299CID000005184
DrugPRE-084

GRIN2A GRIN2B GRIN2C GRIN2D

2.21e-06171294CID000126402
DrugADCI

GRIN2A GRIN2B GRIN2C GRIN2D

2.21e-06171294CID000130099
DrugSKF 82958

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D

2.66e-06391295CID000001225
Drug7-OH-DPAT

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D

2.66e-06391295CID000001219
Drug3-hydroxyglutaric acid

GRIN2A GRIN2B GRIN2C GRIN2D

2.83e-06181294CID000181976
Drugphaclofen

GRIN2A GRIN2B GRIN2C GRIN2D PHEX GABRA6

2.87e-06701296CID000001641
Drugfentanyl

DRD5 HTR4 GRIN2A GRIN2B GRIN2C GRIN2D SLC12A1

3.31e-061111297CID000003345
Drug5'-GMP Na2

GBP7 GBP1 GBP2 GRIN2A GRIN2B GRIN2C GRIN2D PHEX CELSR3 GBP5 AQR

3.37e-0633512911CID000000761
DrugL000369

CLTCL1 GRIN2A GRIN2B GRIN2C GRIN2D

3.44e-06411295CID003931705
DrugAC1NNRU4

GRIN2A GRIN2B GRIN2C GRIN2D SLC12A1

3.44e-06411295CID005126051
DrugC22H28N2O4

GRIN2A GRIN2B GRIN2C GRIN2D

3.57e-06191294CID000065570
Drugmorphine hydrochloride

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D ADCY3 ACKR3 AGTR1 TACR1 LRBA HRH3 KCNH5 GABRA6

3.61e-0648112913CID000004253
DrugMAMP

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D TACR1 HRH3 GABRA6

3.70e-061601298CID000001206
Drug2,4,4'-trichlorobiphenyl

RAG1 STAB2 HTR4 TMPRSS13 INTS7 ABCA13 MAS1 FTSJ1 GRIN2A GRIN2B GRIN2C RALGAPA2 CSMD3 URB1 CELSR3 TMTC3 GBP4 ASXL3 GPR75 PCDH11X MROH7 LRBA HRH3

4.08e-06141112923ctd:C081766
DrugIDRA 21

GRIN2A GRIN2B GRIN2C GRIN2D

4.44e-06201294CID000003688
Drugsaclofen

GRIN2A GRIN2B GRIN2C GRIN2D GABRA6

4.91e-06441295CID000122150
DrugAC1L1JJR

DRD5 GRIN2A GRIN2B GRIN2C GRIN2D

4.91e-06441295CID000005072
Drugcarbetapentane

GRIN2A GRIN2B GRIN2C GRIN2D

5.46e-06211294CID000002562
Drug2,4,5,2',5'-pentachlorobiphenyl

RAG1 STAB2 HTR4 TMPRSS13 INTS7 ABCA13 MAS1 FTSJ1 GRIN2A GRIN2B GRIN2C RALGAPA2 CSMD3 URB1 CELSR3 TMTC3 GBP4 ASXL3 GPR75 PCDH11X MROH7 LRBA HRH3

5.78e-06144112923ctd:C009828
DrugNS 102

GRIN2A GRIN2B GRIN2C GRIN2D

6.65e-06221294CID005282252
DrugCX516

GRIN2A GRIN2B GRIN2C GRIN2D

6.65e-06221294CID000148184
DrugGTP[S]

DRD5 CLTCL1 MLNR FPR3 PTGER4 ADCY3 TG SNAP91 AGTR1 PKD1 PKD2 TACR1 LRBA HRH3

6.82e-0659112914CID000001764
Drugflurothyl

GRIN2A GRIN2B GRIN2C GRIN2D GABRA6

6.85e-06471295CID000009528
Drugacetylcholine

DRD5 HTR4 MLNR GRIN2A GRIN2B GRIN2C GRIN2D ADCY3 AGTR1 TACR1 HRH3

6.86e-0636112911CID000000187
DrugOne-time

DRD5 CLTCL1 GRIN2A GRIN2B GRIN2C

7.61e-06481295CID000040813
Drug2-butenedioate

DRD5 HTR4 GRIN2A GRIN2B GRIN2C GRIN2D SNAP91 UBR5 HRH3

7.72e-062341299CID000000723
DrugD-G-G

GRIN2A GRIN2B GRIN2C GRIN2D

8.01e-06231294CID000444866
DrugYM90K

GRIN2A GRIN2B GRIN2C GRIN2D

8.01e-06231294CID005486547
Drug5,7-dichlorokynurenic acid

GRIN2A GRIN2B GRIN2C GRIN2D TACR1

8.43e-06491295CID000001779
DrugAC1L1FA8

GRIN2A GRIN2B GRIN2C GRIN2D ADCY3

9.33e-06501295CID000003150
Druganiracetam

SPEG GRIN2A GRIN2B GRIN2C GRIN2D TMTC3 AQR

9.43e-061301297CID000002196
DrugNSC7524

GRIN2A GRIN2B GRIN2C GRIN2D ADCY3 PKD1 PKD2 TACR1

9.56e-061821298CID000005657
DrugCGP 39653

GRIN2A GRIN2B GRIN2C GRIN2D

9.57e-06241294CID006437837
Diseaseplacental insufficiency (biomarker_via_orthology)

GRIN2A GRIN2B AGTR1

3.71e-0681213DOID:3891 (biomarker_via_orthology)
Diseasekallistatin measurement

SERPINA3 SERPINA12 SERPINA9

3.71e-0681213EFO_0008196
Diseaseepilepsy (implicated_via_orthology)

GRIN2A GRIN2B GRIN2C GRIN2D SLC12A1 TMTC3 KCNH5

5.14e-061631217DOID:1826 (implicated_via_orthology)
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

PKD1 PKD2 KIF28P

2.37e-05141213DOID:898 (implicated_via_orthology)
DiseaseDepressive disorder

DRD5 HTR4 GRIN2A GRIN2B TG SLCO1C1 TACR1 GABRA6

2.66e-052891218C0011581
Diseasecathepsin L1 measurement

SERPINA3 LRRK2 PLXDC2

3.62e-05161213EFO_0010619
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GRIN2A GRIN2B GRIN2C GRIN2D

4.94e-05491214DOID:0060037 (implicated_via_orthology)
DiseaseAutosomal dominant polycystic kidney disease

PKD1 PKD2

4.99e-0531212cv:C0085413
DiseaseTourette syndrome

FPR3 CSMD3 PICALM PHEX

5.35e-05501214EFO_0004895
Diseaseautosomal dominant polycystic kidney disease (is_implicated_in)

PKD1 PKD2

9.95e-0541212DOID:898 (is_implicated_in)
Diseasegallbladder carcinoma (is_implicated_in)

CLPTM1L UBR5

1.65e-0451212DOID:4948 (is_implicated_in)
Diseaselaryngeal carcinoma (is_marker_for)

UBR5 ACKR3

2.47e-0461212DOID:2600 (is_marker_for)
DiseasePolycystic Kidney Diseases

PKD1 PKD2

2.47e-0461212C0022680
DiseasePolycystic kidney disease, type 2

PKD1 PKD2

3.46e-0471212C2751306
Diseasecognitive disorder (biomarker_via_orthology)

GRIN2A GRIN2B

4.59e-0481212DOID:1561 (biomarker_via_orthology)
Diseasehelping behavior measurement

TMEM33 SLC52A3

4.59e-0481212EFO_0008538
Diseasecystitis (implicated_via_orthology)

PTGER4 TACR1

4.59e-0481212DOID:1679 (implicated_via_orthology)
DiseasePolycystic Kidney, Type 1 Autosomal Dominant Disease

PKD1 PKD2

4.59e-0481212C0887850
Diseaseskin disease, response to cetuximab

ZNF827 TACR1

5.89e-0491212EFO_0000701, EFO_0007682
DiseasePolycystic Kidney, Autosomal Dominant

PKD1 PKD2

5.89e-0491212C0085413
DiseaseMental Depression

HTR4 GRIN2A GRIN2B SLCO1C1 TACR1 GABRA6

6.46e-042541216C0011570
DiseaseMood Disorders

HTR4 GRIN2A ADCY3 TACR1 GABRA6

6.58e-041681215C0525045
DiseaseAlzheimer's disease (is_marker_for)

DRD5 GRIN2A GRIN2B CCNG1 SNAP91 AGTR1

6.87e-042571216DOID:10652 (is_marker_for)
Diseasecolitis (biomarker_via_orthology)

LCT ICOS TACR1

6.87e-04421213DOID:0060180 (biomarker_via_orthology)
DiseaseBipolar Disorder

DRD5 HTR4 RASGRF1 ABCA13 GRIN2A GRIN2B ADCY3 TACR1

8.05e-044771218C0005586
Diseasegastric adenocarcinoma (is_implicated_in)

ABCA13 UBR5

8.95e-04111212DOID:3717 (is_implicated_in)
Diseasehyperhomocysteinemia (implicated_via_orthology)

GRIN2A GRIN2B

8.95e-04111212DOID:9279 (implicated_via_orthology)
Diseasevascular dementia (is_marker_for)

GRIN2A GRIN2B

8.95e-04111212DOID:8725 (is_marker_for)
Diseaseintracranial aneurysm (is_implicated_in)

PKD1 PKD2

1.07e-03121212DOID:10941 (is_implicated_in)
DiseaseEpilepsy

GRIN2A GRIN2B ASXL3 KCNH5

1.07e-031091214C0014544
DiseaseCommon variable immunodeficiency

ICOS LRBA

1.26e-03131212cv:C0009447
Diseaseegg allergy measurement, parental genotype effect measurement

TAF1B GRIN2B

1.26e-03131212EFO_0005939, EFO_0007018
DiseaseConnective Tissue Diseases

PKD1 PKD2

1.26e-03131212C0009782
Diseasecorpus callosum posterior volume measurement

ZBTB4 ATP13A2 CFAP54

1.28e-03521213EFO_0010298
Diseasemyocarditis (implicated_via_orthology)

PTGER4 ICOS

1.47e-03141212DOID:820 (implicated_via_orthology)
Diseasesevere combined immunodeficiency (is_implicated_in)

RAG1 PTPRC

1.47e-03141212DOID:627 (is_implicated_in)
Diseasepolycystic kidney disease (implicated_via_orthology)

PKD1 PKD2

1.47e-03141212DOID:0080322 (implicated_via_orthology)
Diseaseglycerate measurement

HMCN1 SLC23A3

1.69e-03151212EFO_0021029
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

TMEM67 PKD1

1.93e-03161212DOID:0110861 (implicated_via_orthology)
Diseasehypertension (implicated_via_orthology)

RAG1 MAS1 AGTR1 HRH3

1.94e-031281214DOID:10763 (implicated_via_orthology)
Diseaseresponse to vaccine, cytokine measurement

GRIN2B PHEX ZNF827 SLC4A4

2.11e-031311214EFO_0004645, EFO_0004873
Diseasecutaneous melanoma, hair color

MED13L PIGU CLPTM1L

2.13e-03621213EFO_0000389, EFO_0003924
Disease4-ethylphenylsulfate measurement

ATP8B4 TACR1

2.44e-03181212EFO_0021148
Diseaseprotein Z-dependent protease inhibitor measurement

SERPINA12 SERPINA9

2.44e-03181212EFO_0021849
Diseaselifestyle measurement, anxiety disorder measurement

PICALM URB1 CFAP54 LRBA

2.48e-031371214EFO_0007795, EFO_0010724
DiseaseParkinson's disease (is_marker_for)

DRD5 LRRK2 AGTR1

2.66e-03671213DOID:14330 (is_marker_for)
DiseaseOmenn Syndrome

RAG1 PTPRC

2.72e-03191212C2700553
Diseasetemporal lobe epilepsy (is_marker_for)

RASGRF1 GRIN2B

3.02e-03201212DOID:3328 (is_marker_for)
DiseaseSevere Combined Immunodeficiency

RAG1 PTPRC

3.02e-03201212C0085110
DiseaseManic Disorder

DRD5 GRIN2A TACR1

3.14e-03711213C0024713
Diseasegrip strength measurement

RASGRF1 TAF1B ADCY3 SLCO1C1 PKD1 ZBTB21

3.27e-033501216EFO_0006941
Diseasefetal hemoglobin measurement

YTHDC2 PHEX

3.33e-03211212EFO_0004576
DiseaseHbA1c measurement, response to sulfonylurea

GXYLT1 GRIN2A

3.33e-03211212EFO_0004541, EFO_0007922
Diseasenasopharyngeal neoplasm

PIGU ADCY3 CLPTM1L ADGRA3

3.52e-031511214EFO_0004252
DiseaseAttention Deficit Disorder

DRD5 TACR1

3.65e-03221212C0041671
Diseasedilated cardiomyopathy (biomarker_via_orthology)

MAS1 AGTR1

3.65e-03221212DOID:12930 (biomarker_via_orthology)
DiseaseC-peptide measurement

LRRK2 SERPINA12

3.65e-03221212EFO_0005187
DiseaseMinimal Brain Dysfunction

DRD5 TACR1

3.65e-03221212C1321905
DiseaseParkinson disease

LRRK2 ATP13A2

3.65e-03221212cv:C0030567
DiseaseHuntington's disease (is_implicated_in)

GRIN2A GRIN2B

3.99e-03231212DOID:12858 (is_implicated_in)
Diseaseurate measurement, bone density

TAF1B GRIN2C TG CCNG1 GBP4 GBP5 KCNH5 GABRA6

4.06e-036191218EFO_0003923, EFO_0004531
DiseaseManic

DRD5 GRIN2A TACR1

4.09e-03781213C0338831

Protein segments in the cluster

PeptideGeneStartEntry
LSNFLNDSSYALQAV

CFAP54

1136

Q96N23
NADYVISLAFISFSI

CSMD3

1621

Q7Z407
LVSFSSFIYFASLNV

ABCA10

141

Q8WWZ4
SANVDFAFSLYKQLV

SERPINA3

51

P01011
ARQLLAYTVEAANFS

ADGRA3

441

Q8IWK6
ASVSFNLYASVFLLT

AGTR1

106

P30556
VFRNSSLFALANVYA

DYNLT5

161

Q8N7M0
YLLSAFFSQANTAAL

ABCA13

3666

Q86UQ4
LTDTNNIAYLFLSAA

ABCC9

1201

O60706
FSTANAGLLYDFQLI

AQR

1166

O60306
YLASRNTLFNLSNFL

SNAP91

96

O60641
LVTYQLLAFLDFNNT

ATP8B4

526

Q8TF62
RLSTSALNNEFFAYA

ASXL3

301

Q9C0F0
AFIFLSQSLEYAKNS

MROH7

1196

Q68CQ1
QYSFNSQRFAELLST

RAG1

911

P15918
NSSLNPVIYAFNADF

DRD5

351

P21918
LLSNILAAYSFVSEN

EVA1A

16

Q9H8M9
DYFSTQFLLNFAILG

INTS7

886

Q9NVH2
NTVVANASFTYLTAL

LRWD1

621

Q9UFC0
ATTAFQFLQLYYSLL

CCNG1

151

P51959
QATNFIAFAAQYRSS

MUC4

4731

Q99102
RANISYTLLFFLFLA

OR1B1

21

Q8NGR6
LIYLVSSFLALNQAS

LYZL6

6

O75951
PFASLNFLDYISSNN

MED13L

1236

Q71F56
LLFSTINSSANPFIY

MAS1

266

P04201
LFLFSYATAAQNNTV

MTMR12

181

Q9C0I1
TRTFNYNFSALANTV

ELAPOR1

666

Q6UXG2
TICYLNLALADFSFS

FPR3

61

P25089
LLKVLDFYTAFANSF

KCNH5

646

Q8NCM2
FFVALATVENYLLAS

OR5B2

101

Q96R09
AGLTLFAVYASNVLF

PTGER4

136

P35408
QINALTSFLDASFVY

LPO

296

P22079
FCSLLYAFSQLAVSL

GXYLT1

16

Q4G148
LFSEALNAAQIFAIY

LRBA

366

P50851
VLAYNLNYATAISSF

LCT

1686

P09848
SQLFSYAAFSDSNII

LRRK2

2341

Q5S007
IASSATAFYLQLFLL

MFSD2B

56

A6NFX1
FALAVLLSSTFVYNS

GBP1

116

P32455
FALAILLSSTFVYNS

GBP2

116

P32456
FALAVLLSSSFVYNS

GBP4

131

Q96PP9
FALALLLSSTFVYNT

GBP5

116

Q96PP8
FALAVLLCSTFVYNS

GBP6

116

Q6ZN66
FALAVLLSSSFVYNS

GBP7

116

Q8N8V2
SALIEFAAVNYFTNL

GABRA6

316

Q16445
SALNSSANPIIYFFV

MRGPRX3

261

Q96LB0
FFLTNLSLVDVSYAT

OR2F1

61

Q13607
FFLTNLSLVDVSYAT

OR2F2

61

O95006
VFSNQFLLETAAYLD

PCDH11X

411

Q9BZA7
ADLDFIQQAISYSSF

OLR1

186

P78380
LQLFVFNDSTLISYL

RALGAPA2

1426

Q2PPJ7
LSAIFLALATYQSLY

PIGU

181

Q9H490
LSSNGSFILYQFELF

GPR75

346

O95800
IIFNSANRLFQYAST

MEF2B

46

Q02080
SYLISLFLIINSSAN

MAS1L

296

P35410
FLFALLYSSLAQDAS

HMCN1

11

Q96RW7
SYNDCAAQLFFTILL

OR6C74

91

A6NCV1
QLSNNSVSFFLYNLD

ICOS

86

Q9Y6W8
ASLLFLNVLAFAALY

NLGN3

716

Q9NZ94
FSLSSFQYLILAAAV

ATP13A2

1051

Q9NQ11
FYFLLARAISASSDQ

ACKR3

231

P25106
NYFIVSLAFADLLVS

HTR4

56

Q13639
LITAQIFSYLGLNFA

ADCY3

146

O60266
AQQLSNVYFTILSLF

ASB5

11

Q8WWX0
SGILINTFSLAFYSF

MS4A4A

146

Q96JQ5
FLSVTFFNLSIYLNI

HRH3

211

Q9Y5N1
ALSSFLNKASAVYQA

LYPLAL1

146

Q5VWZ2
SDLQANDYFNIISFS

ITIH6

311

Q6UXX5
YFDNILNSFIVSSLQ

HMSD

121

A8MTL9
LSFATVQQSGLLFYN

CELSR3

1541

Q9NYQ7
FAALTASQEFLNYLR

KIF28P

756

B7ZC32
FNIVALQLFYLSASI

MLNR

336

O43193
VLASTASIFLAYNAF

NUP210L

1821

Q5VU65
YLLTVLASNAFENLT

PKD1

1101

P98161
DLACQNFILASFLTY

TMEM67

951

Q5HYA8
LSDVRFFLNQYSASV

FIBP

321

O43427
SLSIFYFLKIANFSN

TAS2R10

101

Q9NYW0
YIFNAIALFLSTSNI

TAS2R40

256

P59535
LSANFSYNALTALDS

STK11IP

166

Q8N1F8
AFIYTLVAFVNALTN

SLC52A3

301

Q9NQ40
FLSFQDASSLYRNIL

SLITRK6

746

Q9H5Y7
IYNASVSLALYALFL

TMEM184A

226

Q6ZMB5
SLSYQFILNLFSFLL

TAF1B

536

Q53T94
VTNYFLVNLAFAEAS

TACR1

66

P25103
DNYNLGSFTFQATLL

PLXDC2

236

Q6UX71
NTAIALSFLIYFISA

SLC38A6

286

Q8IZM9
ISNFFLASYALINFS

SLC12A1

571

Q13621
AFVSKNNSYSLAFLA

RNF169

266

Q8NCN4
SALNSSANPIIYFFV

MRGPRX1

261

Q96LB2
LLQNLLFYFESDSSS

RASGRF1

46

Q13972
LASSFTALLQAAYES

URB1

886

O60287
TQAVVLSAGFSSFYL

SLC23A3

431

Q6PIS1
ASQVYSLNTDFAFRL

SERPINA9

41

Q86WD7
NFYSAETILTNFQNL

SERPINA12

156

Q8IW75
ADSYFSLLQGFINSL

BROX

61

Q5VW32
LFLYFTSTLQNFSLC

CYP2G1P

101

Q6ZSU1
DTNLYFLALTFFVAA

CLPTM1L

281

Q96KA5
LLYSNVSNFARLAST

CLTCL1

1216

P53675
YLASRNTLFNLSNFL

PICALM

96

Q13492
NVLAASSEYFQSLFT

ZBTB21

46

Q9ULJ3
DFANSFSILRYNSTI

TMPRSS13

281

Q9BYE2
LIANVTFGYTSANFS

REV3L

2726

O60673
FQLYPNTSQSATLFL

SPEG

3181

Q15772
FTVTYTLLNNLQDFL

TRAPPC14

386

Q8WVR3
FLIQASAQDTAYLYA

RANBP3L

386

Q86VV4
FLYLCTSTVQFNSLF

SLCO1C1

356

Q9NYB5
LSANITAFSNYSATL

TRIM75

216

A6NK02
FSDVLNFIYSARLAL

ZBTB4

136

Q9P1Z0
TVNAFYSASTNQIRF

PHEX

536

P78562
NFLTEVLAYSNSSAR

STAB2

2326

Q8WWQ8
AANALFTSVFLYQSL

TMEM201

651

Q5SNT2
ATFIDFSVYNANINL

PKD2

421

Q13563
LENYTNLVSLDFNFT

ZNF404

36

Q494X3
YVANSASALFSQDIS

ZNF827

556

Q17R98
LYSQLQVFFSSVLCA

FTSJ1

166

Q9UET6
LSSAALDVNLFIRYF

YTHDC2

346

Q9H6S0
SDYFSFVLSLASLNA

USP24

2136

Q9UPU5
FYDALNIQALSAILF

SLC4A4

461

Q9Y6R1
NAANEFLYSQTFSLS

TBX4

511

P57082
TFSNILSSAFLGYVL

TMEM42

106

Q69YG0
FLAQTNGNYLALFST

WDR25

441

Q64LD2
DFRSALFNLALLYSQ

TMTC3

701

Q6ZXV5
STSYNSKALIAFLAF

PTPRC

571

P08575
EAASGNFSLFIQSLY

TG

811

P01266
AASFYQRALLANALT

TMEM33

51

P57088
VARSFYTAIAQAFLS

UBR5

2291

O95071
FFAVIFLASYTANLA

GRIN2A

636

Q12879
AFFAVIFLASYTANL

GRIN2B

636

Q13224
AVIFLASYTANLAAF

GRIN2C

636

Q14957
AVIFLASYTANLAAF

GRIN2D

666

O15399