Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RALGAPA1 EEF1D RAP1GAP IQGAP2 CYTH3 LRRK2 RACGAP1 ARHGEF26 SMCR8 PLXNB1 OPHN1 IQGAP1

4.47e-075077612GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RALGAPA1 EEF1D RAP1GAP IQGAP2 CYTH3 LRRK2 RACGAP1 ARHGEF26 SMCR8 PLXNB1 OPHN1 IQGAP1

4.47e-075077612GO:0030695
GeneOntologyMolecularFunctionGTPase activator activity

RALGAPA1 RAP1GAP IQGAP2 LRRK2 RACGAP1 SMCR8 PLXNB1 OPHN1 IQGAP1

1.12e-06279769GO:0005096
GeneOntologyMolecularFunctionenzyme activator activity

RALGAPA1 NLRP12 RAP1GAP ERCC5 IQGAP2 LRRK2 RACGAP1 SMCR8 CDK5R2 PLXNB1 OPHN1 IQGAP1

6.48e-066567612GO:0008047
GeneOntologyMolecularFunctionenzyme regulator activity

CCNF RALGAPA1 NLRP12 EEF1D RAP1GAP ERCC5 SERPINB13 IQGAP2 CYTH3 LRRK2 RACGAP1 ARHGEF26 SMCR8 CDK5R2 PLXNB1 OPHN1 IQGAP1

1.86e-0514187617GO:0030234
GeneOntologyMolecularFunctionphosphatidylinositol-3,4,5-trisphosphate binding

IQGAP2 CYTH3 RACGAP1 IQGAP1

3.61e-0549764GO:0005547
GeneOntologyMolecularFunctionmicrotubule binding

DST DCDC1 LRRK2 RACGAP1 DYNC1I1 MX1 CFAP157

1.71e-04308767GO:0008017
GeneOntologyMolecularFunctionsmall GTPase binding

EXOC5 RAP1GAP IQGAP2 IFT20 LRRK2 YBX3 IQGAP1

2.20e-04321767GO:0031267
GeneOntologyMolecularFunctioncytoskeletal protein binding

DST DCDC1 IQGAP2 MYO7A SYNE1 LRRK2 RACGAP1 CDK5R2 DYNC1I1 OPHN1 MX1 IQGAP1 CFAP157

2.38e-0410997613GO:0008092
GeneOntologyMolecularFunctionGTPase binding

EXOC5 RAP1GAP IQGAP2 IFT20 LRRK2 YBX3 IQGAP1

4.39e-04360767GO:0051020
GeneOntologyMolecularFunctionactin binding

DST IQGAP2 MYO7A SYNE1 LRRK2 CDK5R2 OPHN1 IQGAP1

4.67e-04479768GO:0003779
GeneOntologyMolecularFunctionsemaphorin receptor activity

PLXND1 PLXNB1

9.21e-0412762GO:0017154
GeneOntologyMolecularFunctionJUN kinase kinase kinase activity

LRRK2 RIPK2

9.21e-0412762GO:0004706
GeneOntologyMolecularFunctionGTPase inhibitor activity

IQGAP2 IQGAP1

1.09e-0313762GO:0005095
GeneOntologyMolecularFunctiontubulin binding

DST DCDC1 LRRK2 RACGAP1 DYNC1I1 MX1 CFAP157

1.21e-03428767GO:0015631
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

CUL3 STX2 NLRP12 SPAG4 TCERG1L SYNE1 LRRK2 RIPK2 SMARCC1 RACGAP1 DYNC1LI1 IQGAP1

1.37e-0311607612GO:0030674
GeneOntologyMolecularFunctionmolecular adaptor activity

IPPK CUL3 STX2 NLRP12 SPAG4 TCERG1L SYNE1 LRRK2 RIPK2 SMARCC1 RACGAP1 DYNC1LI1 IQGAP1

1.70e-0313567613GO:0060090
GeneOntologyMolecularFunctiondynein heavy chain binding

DYNC1LI1 DYNC1I1

1.87e-0317762GO:0045504
GeneOntologyMolecularFunctionmolecular function activator activity

RALGAPA1 NLRP12 RAP1GAP ERCC5 IQGAP2 LRRK2 RACGAP1 SMCR8 CDK5R2 PLXNB1 OPHN1 IQGAP1

2.30e-0312337612GO:0140677
GeneOntologyBiologicalProcessmitotic cytokinesis

STX2 EXOC5 DCDC1 IQGAP2 CHMP1B RACGAP1 IQGAP1

5.40e-0895757GO:0000281
GeneOntologyBiologicalProcesscytoskeleton-dependent cytokinesis

STX2 EXOC5 DCDC1 IQGAP2 CHMP1B RACGAP1 IQGAP1

3.98e-07127757GO:0061640
GeneOntologyBiologicalProcesscytokinesis

CUL3 STX2 EXOC5 DCDC1 IQGAP2 CHMP1B RACGAP1 IQGAP1

7.63e-07204758GO:0000910
GeneOntologyBiologicalProcesscytokinetic process

STX2 IQGAP2 CHMP1B RACGAP1 IQGAP1

8.42e-0748755GO:0032506
GeneOntologyBiologicalProcessregulation of GTPase activity

RALGAPA1 RAP1GAP IQGAP2 LRRK2 PLXND1 ARHGEF26 SMCR8 PLXNB1 IQGAP1

3.46e-06335759GO:0043087
GeneOntologyBiologicalProcessactomyosin contractile ring assembly

IQGAP2 RACGAP1 IQGAP1

3.82e-069753GO:0000915
GeneOntologyBiologicalProcessassembly of actomyosin apparatus involved in cytokinesis

IQGAP2 RACGAP1 IQGAP1

3.82e-069753GO:0000912
GeneOntologyBiologicalProcessactomyosin contractile ring organization

IQGAP2 RACGAP1 IQGAP1

5.44e-0610753GO:0044837
GeneOntologyBiologicalProcessmitotic cytokinetic process

STX2 IQGAP2 CHMP1B IQGAP1

6.09e-0633754GO:1902410
GeneOntologyBiologicalProcesscell division

CCNF CUL3 STX2 NCAPD3 EXOC5 DCDC1 IQGAP2 CHMP1B RACGAP1 DYNC1LI1 DICER1 IQGAP1

7.50e-066977512GO:0051301
GeneOntologyBiologicalProcessorganelle localization

CUL3 STX2 EXOC5 MYO7A CHMP1B LSG1 UCHL1 SYNE1 LRRK2 RACGAP1 DYNC1I1 MFN1

8.17e-067037512GO:0051640
GeneOntologyBiologicalProcessmitotic cell cycle process

CCNF CUL3 STX2 NCAPD3 EXOC5 DCDC1 IQGAP2 CHMP1B SMARCC1 RACGAP1 DYNC1LI1 LSM14A IQGAP1

1.13e-058547513GO:1903047
GeneOntologyBiologicalProcesscell morphogenesis

CUL3 CPNE6 DST MYO7A UCHL1 SYNE1 LRRK2 PLXND1 ARHGEF26 DICER1 CDK5R2 PLXNB1 MFN1 OPHN1 IQGAP1

2.15e-0511947515GO:0000902
GeneOntologyBiologicalProcessestablishment of organelle localization

CUL3 EXOC5 MYO7A CHMP1B LSG1 UCHL1 SYNE1 LRRK2 RACGAP1 DYNC1I1

2.75e-055467510GO:0051656
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

STX2 EXOC5 ABCC4 RAP1GAP IFT52 IFT20 CEP162 SYNE1 ARHGEF26 OPHN1 CFAP157

2.90e-056707511GO:0120031
GeneOntologyBiologicalProcessneuron projection morphogenesis

CPNE6 DST UCHL1 SYNE1 LRRK2 PLXND1 DICER1 CDK5R2 PLXNB1 MFN1 OPHN1 IQGAP1

3.02e-058027512GO:0048812
GeneOntologyBiologicalProcesscell projection assembly

STX2 EXOC5 ABCC4 RAP1GAP IFT52 IFT20 CEP162 SYNE1 ARHGEF26 OPHN1 CFAP157

3.55e-056857511GO:0030031
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

CPNE6 DST UCHL1 SYNE1 LRRK2 PLXND1 DICER1 CDK5R2 PLXNB1 MFN1 OPHN1 IQGAP1

3.71e-058197512GO:0120039
GeneOntologyBiologicalProcesssister chromatid segregation

CUL3 NCAPD3 CHMP1B SMARCC1 RACGAP1 DYNC1LI1 LSM14A

3.85e-05254757GO:0000819
GeneOntologyBiologicalProcessmitotic actomyosin contractile ring assembly

IQGAP2 IQGAP1

3.90e-053752GO:1903475
GeneOntologyBiologicalProcessmitotic actomyosin contractile ring assembly actin filament organization

IQGAP2 IQGAP1

3.90e-053752GO:1903479
GeneOntologyBiologicalProcessassembly of actomyosin apparatus involved in mitotic cytokinesis

IQGAP2 IQGAP1

3.90e-053752GO:1902407
GeneOntologyBiologicalProcesscell projection morphogenesis

CPNE6 DST UCHL1 SYNE1 LRRK2 PLXND1 DICER1 CDK5R2 PLXNB1 MFN1 OPHN1 IQGAP1

4.03e-058267512GO:0048858
GeneOntologyBiologicalProcessorganelle assembly

EXOC5 ABCC4 IFT52 MYO7A IFT20 CHMP1B CEP162 SYNE1 LRRK2 RACGAP1 LSM14A SMCR8 DICER1 CFAP157

5.32e-0511387514GO:0070925
GeneOntologyBiologicalProcessmitotic cell cycle

CCNF CUL3 STX2 NCAPD3 EXOC5 DCDC1 IQGAP2 CHMP1B SMARCC1 RACGAP1 DYNC1LI1 LSM14A IQGAP1

6.73e-0510147513GO:0000278
GeneOntologyBiologicalProcessregulation of hydrolase activity

RALGAPA1 NLRP12 RAP1GAP SERPINB13 IQGAP2 LRRK2 RIPK2 PLXND1 ARHGEF26 SMCR8 PLXNB1 IQGAP1

7.25e-058787512GO:0051336
GeneOntologyBiologicalProcessactomyosin contractile ring assembly actin filament organization

IQGAP2 IQGAP1

7.79e-054752GO:2000689
GeneOntologyBiologicalProcessmicrotubule-based process

CCNF IFT52 DST IFT20 CHMP1B UCHL1 RACGAP1 DYNC1LI1 LSM14A APOB DICER1 DYNC1I1 CFAP157

1.03e-0410587513GO:0007017
GeneOntologyBiologicalProcessmitotic sister chromatid segregation

CUL3 NCAPD3 CHMP1B RACGAP1 DYNC1LI1 LSM14A

1.23e-04212756GO:0000070
GeneOntologyBiologicalProcessneuron projection development

CPNE6 DST MYO7A IFT20 UCHL1 SYNE1 LRRK2 PLXND1 DICER1 CDK5R2 PLXNB1 MFN1 OPHN1 IQGAP1

1.93e-0412857514GO:0031175
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

CUL3 RALGAPA1 RAP1GAP CYTH3 RACGAP1 PLXNB1 OPHN1

2.08e-04333757GO:0051056
GeneOntologyBiologicalProcesschromosome segregation

CUL3 NCAPD3 CHMP1B SMARCC1 RACGAP1 DYNC1LI1 LSM14A DICER1

2.83e-04465758GO:0007059
GeneOntologyBiologicalProcessregulation of organelle organization

CCNF CUL3 NCAPD3 IQGAP2 IFT20 CHMP1B SYNE1 LRRK2 SMARCC1 DYNC1LI1 PARN SMCR8 PLXNB1 MFN1

3.02e-0413427514GO:0033043
GeneOntologyBiologicalProcessnuclear chromosome segregation

CUL3 NCAPD3 CHMP1B SMARCC1 RACGAP1 DYNC1LI1 LSM14A

3.12e-04356757GO:0098813
GeneOntologyBiologicalProcessRho protein signal transduction

CUL3 LRRK2 RACGAP1 PLXNB1 OPHN1

3.29e-04164755GO:0007266
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

CUL3 NCAPD3 RAP1GAP CYP2J2 IFT20 SYNE1 LRRK2 PARN CPB2 PLXND1 SMCR8 PLXNB1 MFN1 IQGAP1

3.61e-0413667514GO:0051130
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

DST MYO7A UCHL1 SYNE1 LRRK2 PLXND1 CDK5R2 PLXNB1 MFN1 OPHN1

3.65e-047487510GO:0048667
GeneOntologyBiologicalProcessmicrotubule-based movement

IFT52 DST IFT20 UCHL1 DYNC1LI1 APOB DYNC1I1 CFAP157

4.17e-04493758GO:0007018
GeneOntologyBiologicalProcessregulation of nervous system process

SYNE1 LRRK2 CACNG4 DICER1 HOMER3

4.44e-04175755GO:0031644
GeneOntologyBiologicalProcesssnRNA transcription by RNA polymerase III

ICE2 SNAPC1

4.62e-049752GO:0042796
GeneOntologyBiologicalProcessestablishment of epithelial cell polarity

IFT20 CYTH3 OPHN1

4.79e-0442753GO:0090162
GeneOntologyBiologicalProcessprotein-containing complex localization

IFT52 IFT20 LSG1 SYNE1 CACNG4 OPHN1

5.25e-04278756GO:0031503
GeneOntologyBiologicalProcessguanine nucleotide transmembrane transport

ABCC4 LRRC8B

5.76e-0410752GO:1903790
GeneOntologyBiologicalProcesscortical actin cytoskeleton organization

IQGAP2 RACGAP1 IQGAP1

5.87e-0445753GO:0030866
GeneOntologyBiologicalProcesscell cycle process

CCNF CUL3 STX2 NCAPD3 EXOC5 DCDC1 IQGAP2 CHMP1B SMARCC1 RACGAP1 DYNC1LI1 LSM14A DICER1 IQGAP1

6.17e-0414417514GO:0022402
GeneOntologyBiologicalProcesscyclic nucleotide transport

ABCC4 LRRC8B

7.02e-0411752GO:0070729
GeneOntologyBiologicalProcessguanine nucleotide transport

ABCC4 LRRC8B

7.02e-0411752GO:0001408
GeneOntologyBiologicalProcessneuron development

CPNE6 DST MYO7A IFT20 UCHL1 SYNE1 LRRK2 PLXND1 DICER1 CDK5R2 PLXNB1 MFN1 OPHN1 IQGAP1

7.17e-0414637514GO:0048666
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

CUL3 RALGAPA1 RAP1GAP CYTH3 LRRK2 RACGAP1 PLXNB1 OPHN1

7.41e-04538758GO:0007264
GeneOntologyBiologicalProcesstransport along microtubule

IFT52 DST IFT20 UCHL1 DYNC1I1

7.59e-04197755GO:0010970
GeneOntologyBiologicalProcessregulation of autophagosome assembly

IFT20 LRRK2 SMCR8

8.00e-0450753GO:2000785
GeneOntologyBiologicalProcessgamete generation

SPAG4 IFT20 UCHL1 SYNE1 LRRK2 RACGAP1 PARN APOB YBX3 DICER1 CFAP157

8.07e-049827511GO:0007276
GeneOntologyBiologicalProcessnegative regulation of catabolic process

LRRK2 SMARCC1 PARN YBX3 SMCR8 DICER1 OPHN1

8.10e-04418757GO:0009895
GeneOntologyBiologicalProcesssexual reproduction

STX2 NCAPD3 SPAG4 IFT20 UCHL1 SYNE1 LRRK2 RACGAP1 PARN APOB YBX3 DICER1 CFAP157

8.26e-0413127513GO:0019953
GeneOntologyBiologicalProcessintracellular distribution of mitochondria

LRRK2 MFN1

8.41e-0412752GO:0048312
GeneOntologyBiologicalProcessintracellular transport

CUL3 STX2 IFT52 DST MYO7A IFT20 CHMP1B LSG1 UCHL1 SYNE1 LRRK2 DYNC1LI1 CACNG4 DYNC1I1

8.92e-0414967514GO:0046907
GeneOntologyBiologicalProcessnegative regulation of autophagosome assembly

LRRK2 SMCR8

9.92e-0413752GO:1902902
GeneOntologyBiologicalProcessmitotic nuclear division

CUL3 NCAPD3 CHMP1B RACGAP1 DYNC1LI1 LSM14A

1.02e-03316756GO:0140014
GeneOntologyBiologicalProcessorganelle fission

CUL3 NCAPD3 CHMP1B LRRK2 RACGAP1 DYNC1LI1 LSM14A MFN1

1.09e-03571758GO:0048285
GeneOntologyBiologicalProcesscilium assembly

EXOC5 ABCC4 IFT52 IFT20 CEP162 SYNE1 CFAP157

1.15e-03444757GO:0060271
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

RALGAPA1 NLRP12 RAP1GAP LRRK2 RIPK2 PARN ARHGEF26 SMCR8 CDK5R2 PLXNB1 IQGAP1

1.17e-0310287511GO:0043085
GeneOntologyBiologicalProcesscortical cytoskeleton organization

IQGAP2 RACGAP1 IQGAP1

1.17e-0357753GO:0030865
GeneOntologyBiologicalProcessneurotransmitter receptor internalization

SYNE1 CACNG4 OPHN1

1.23e-0358753GO:0099590
GeneOntologyBiologicalProcessnegative regulation of excitatory postsynaptic potential

SYNE1 LRRK2

1.33e-0315752GO:0090394
GeneOntologyBiologicalProcessestablishment of vesicle localization

CUL3 EXOC5 MYO7A LRRK2 DYNC1I1

1.35e-03224755GO:0051650
GeneOntologyBiologicalProcesscytoskeleton-dependent intracellular transport

IFT52 DST IFT20 UCHL1 DYNC1I1

1.37e-03225755GO:0030705
GeneOntologyBiologicalProcessregulation of vacuole organization

IFT20 LRRK2 SMCR8

1.43e-0361753GO:0044088
GeneOntologyCellularComponentmicrotubule

CUL3 SPAG4 DST DCDC1 IQGAP2 CHMP1B CEP162 RACGAP1 DYNC1LI1 CEP170B DYNC1I1 MX1 IQGAP1

5.86e-085337613GO:0005874
GeneOntologyCellularComponentmidbody

STX2 EXOC5 DCDC1 CHMP1B SYNE1 RACGAP1 IQGAP1

1.63e-05222767GO:0030496
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

CUL3 SPAG4 DST DCDC1 IQGAP2 CHMP1B CEP162 RACGAP1 DYNC1LI1 CEP170B DYNC1I1 MX1 IQGAP1

1.95e-058997613GO:0099513
GeneOntologyCellularComponentsupramolecular fiber

CUL3 SPAG4 DST DCDC1 IQGAP2 CHMP1B CEP162 SYNE1 RACGAP1 DYNC1LI1 CEP170B DYNC1I1 MX1 IQGAP1

7.85e-0511797614GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

CUL3 SPAG4 DST DCDC1 IQGAP2 CHMP1B CEP162 SYNE1 RACGAP1 DYNC1LI1 CEP170B DYNC1I1 MX1 IQGAP1

8.43e-0511877614GO:0099081
GeneOntologyCellularComponentspindle

CUL3 DCDC1 CHMP1B CEP162 RACGAP1 DYNC1LI1 LSM14A DYNC1I1

3.09e-04471768GO:0005819
GeneOntologyCellularComponentaxon

CPNE6 RAP1GAP DST UCHL1 LRRK2 PLXND1 DICER1 CDK5R2 DYNC1I1 OPHN1 IQGAP1

3.60e-048917611GO:0030424
GeneOntologyCellularComponentkinetochore

NCAPD3 CHMP1B SMARCC1 DYNC1LI1 DYNC1I1

5.18e-04181765GO:0000776
GeneOntologyCellularComponentcondensed chromosome, centromeric region

NCAPD3 CHMP1B SMARCC1 DYNC1LI1 DYNC1I1

6.92e-04193765GO:0000779
GeneOntologyCellularComponentneuron projection cytoplasm

DST UCHL1 LRRK2 DYNC1I1

6.96e-04110764GO:0120111
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SPAG4 SYNE1

7.02e-0411762GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SPAG4 SYNE1

7.02e-0411762GO:0034993
GeneOntologyCellularComponentnuclear membrane protein complex

SPAG4 SYNE1

7.02e-0411762GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SPAG4 SYNE1

7.02e-0411762GO:0106094
GeneOntologyCellularComponentphotoreceptor connecting cilium

IFT52 MYO7A IFT20

7.10e-0448763GO:0032391
GeneOntologyCellularComponentsemaphorin receptor complex

PLXND1 PLXNB1

9.91e-0413762GO:0002116
GeneOntologyCellularComponentmicrovillus

IQGAP2 MYO7A IFT20 LRRK2

1.06e-03123764GO:0005902
GeneOntologyCellularComponentamphisome

CHMP1B LRRK2

1.33e-0315762GO:0044753
GeneOntologyCellularComponentsomatodendritic compartment

CPNE6 RAP1GAP IFT52 IFT20 UCHL1 SYNE1 LRRK2 APOB CACNG4 DICER1 HOMER3 OPHN1

1.51e-0312287612GO:0036477
GeneOntologyCellularComponentaxon cytoplasm

DST UCHL1 DYNC1I1

1.95e-0368763GO:1904115
GeneOntologyCellularComponentcell leading edge

STX2 DST IQGAP2 CYTH3 PLXND1 ARHGEF26 IQGAP1

2.26e-03500767GO:0031252
GeneOntologyCellularComponentdendrite terminus

IFT52 IFT20

2.38e-0320762GO:0044292
GeneOntologyCellularComponentintraciliary transport particle B

IFT52 IFT20

2.62e-0321762GO:0030992
GeneOntologyCellularComponentglutamatergic synapse

CUL3 EEF1D LRRK2 PARN CACNG4 PLXND1 DICER1 HOMER3 OPHN1

2.79e-03817769GO:0098978
GeneOntologyCellularComponentciliary transition zone

IFT52 MYO7A IFT20

3.21e-0381763GO:0035869
GeneOntologyCellularComponentchromosome, centromeric region

NCAPD3 CHMP1B SMARCC1 DYNC1LI1 DYNC1I1

3.33e-03276765GO:0000775
GeneOntologyCellularComponentcytoplasmic dynein complex

DYNC1LI1 DYNC1I1

3.42e-0324762GO:0005868
GeneOntologyCellularComponentcentriole

CCNF IFT52 IFT20 CEP162

3.58e-03172764GO:0005814
GeneOntologyCellularComponentpostsynapse

CUL3 DST SYNE1 LRRK2 PARN CACNG4 SMCR8 DICER1 HOMER3 OPHN1

3.70e-0310187610GO:0098794
GeneOntologyCellularComponentdendrite

CPNE6 RAP1GAP IFT52 IFT20 SYNE1 LRRK2 DICER1 HOMER3 OPHN1

3.85e-03858769GO:0030425
GeneOntologyCellularComponentdendritic tree

CPNE6 RAP1GAP IFT52 IFT20 SYNE1 LRRK2 DICER1 HOMER3 OPHN1

3.91e-03860769GO:0097447
GeneOntologyCellularComponentintraciliary transport particle

IFT52 IFT20

4.64e-0328762GO:0030990
HumanPhenoTypified by incomplete penetrance

NLRP12 UCHL1 LRRK2 ELP1 SMARCC1 PARN

3.59e-05155226HP:0003829
HumanPhenoInheritance qualifier

NLRP12 CEBPA UCHL1 LRRK2 ELP1 SMARCC1 PARN DICER1

4.08e-05330228HP:0034335
DomainRho_GTPase_activation_prot

IQGAP2 RACGAP1 PLXND1 PLXNB1 OPHN1 IQGAP1

1.32e-0688746IPR008936
DomainP-loop_NTPase

NLRP12 ABCC4 SULT1C2 SULT2A1 MYO7A LSG1 LRRK2 DYNC1LI1 CHD9 DICER1 MFN1 MX1 IQGAP1

2.55e-058487413IPR027417
Domain-

NLRP12 ABCC4 SULT1C2 SULT2A1 MYO7A LSG1 LRRK2 DYNC1LI1 CHD9 DICER1 MFN1 MX1

3.40e-0574674123.40.50.300
DomainRasGAP_C

IQGAP2 IQGAP1

4.63e-053742IPR000593
DomainRasGAP_C

IQGAP2 IQGAP1

4.63e-053742PF03836
DomainRasGAP_dom

IQGAP2 PLXNB1 IQGAP1

4.67e-0518743IPR001936
DomainCH

DST IQGAP2 SYNE1 IQGAP1

1.28e-0465744SM00033
DomainCH

DST IQGAP2 SYNE1 IQGAP1

1.71e-0470744PF00307
Domain-

DST IQGAP2 SYNE1 IQGAP1

1.80e-04717441.10.418.10
DomainCH

DST IQGAP2 SYNE1 IQGAP1

2.01e-0473744PS50021
DomainCH-domain

DST IQGAP2 SYNE1 IQGAP1

2.23e-0475744IPR001715
DomainPlexin_cytopl

PLXND1 PLXNB1

5.48e-049742PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXND1 PLXNB1

5.48e-049742IPR013548
DomainPlexin

PLXND1 PLXNB1

5.48e-049742IPR031148
DomainRap_GAP

RALGAPA1 RAP1GAP

6.83e-0410742PF02145
DomainRap_GAP_dom

RALGAPA1 RAP1GAP

8.32e-0411742IPR000331
DomainRAPGAP

RALGAPA1 RAP1GAP

8.32e-0411742PS50085
DomainWW_DOMAIN_2

TCERG1L IQGAP2 IQGAP1

1.08e-0351743PS50020
DomainWW_DOMAIN_1

TCERG1L IQGAP2 IQGAP1

1.08e-0351743PS01159
DomainWW_dom

TCERG1L IQGAP2 IQGAP1

1.15e-0352743IPR001202
DomainRasGAP

IQGAP2 IQGAP1

1.37e-0314742SM00323
DomainG_DYNAMIN_dom

MFN1 MX1

1.37e-0314742IPR030381
DomainRasGAP_CS

IQGAP2 IQGAP1

1.37e-0314742IPR023152
DomainG_DYNAMIN_2

MFN1 MX1

1.37e-0314742PS51718
DomainRasGAP

IQGAP2 IQGAP1

1.57e-0315742PF00616
DomainDynamin_GTPase

MFN1 MX1

1.57e-0315742IPR001401
DomainDynamin_N

MFN1 MX1

1.57e-0315742PF00350
DomainRAS_GTPASE_ACTIV_1

IQGAP2 IQGAP1

1.57e-0315742PS00509
DomainRAS_GTPASE_ACTIV_2

IQGAP2 IQGAP1

1.57e-0315742PS50018
DomainDynamin_SF

MFN1 MX1

1.57e-0315742IPR022812
Domain-

IQGAP2 IQGAP1

1.79e-03167421.10.506.10
DomainIQ

IQGAP2 MYO7A IQGAP1

2.81e-0371743PF00612
DomainActinin_actin-bd_CS

DST SYNE1

3.71e-0323742IPR001589
DomainSpectrin

DST SYNE1

3.71e-0323742PF00435
DomainACTININ_2

DST SYNE1

3.71e-0323742PS00020
DomainACTININ_1

DST SYNE1

3.71e-0323742PS00019
DomainIQ

IQGAP2 MYO7A IQGAP1

4.08e-0381743SM00015
DomainIPT

PLXND1 PLXNB1

5.10e-0327742SM00429
DomainIQ_motif_EF-hand-BS

IQGAP2 MYO7A IQGAP1

5.48e-0390743IPR000048
DomainSpectrin_repeat

DST SYNE1

5.87e-0329742IPR002017
DomainIQ

IQGAP2 MYO7A IQGAP1

6.00e-0393743PS50096
DomainTIG

PLXND1 PLXNB1

6.69e-0331742PF01833
DomainSema

PLXND1 PLXNB1

6.69e-0331742SM00630
DomainSemap_dom

PLXND1 PLXNB1

6.69e-0331742IPR001627
DomainSema

PLXND1 PLXNB1

6.69e-0331742PF01403
DomainSEMA

PLXND1 PLXNB1

6.69e-0331742PS51004
DomainPSI

PLXND1 PLXNB1

7.11e-0332742PF01437
DomainSpectrin/alpha-actinin

DST SYNE1

7.11e-0332742IPR018159
DomainIPT

PLXND1 PLXNB1

7.11e-0332742IPR002909
DomainPlexin_repeat

PLXND1 PLXNB1

7.11e-0332742IPR002165
DomainSPEC

DST SYNE1

7.11e-0332742SM00150
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

CUL3 RALGAPA1 DST IQGAP2 RACGAP1 DYNC1LI1 PLXND1 ARHGEF26 DYNC1I1 PLXNB1 MFN1 OPHN1 IQGAP1

3.82e-066496213MM15690
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

CUL3 RALGAPA1 DST IQGAP2 RACGAP1 DYNC1LI1 PLXND1 ARHGEF26 DYNC1I1 PLXNB1 MFN1 OPHN1 IQGAP1

1.18e-057206213M41838
PathwayREACTOME_RHO_GTPASE_CYCLE

CUL3 RALGAPA1 DST IQGAP2 RACGAP1 PLXND1 ARHGEF26 PLXNB1 OPHN1 IQGAP1

1.95e-054396210MM15595
PathwayREACTOME_RHO_GTPASE_CYCLE

CUL3 RALGAPA1 DST IQGAP2 RACGAP1 PLXND1 ARHGEF26 PLXNB1 OPHN1 IQGAP1

2.41e-054506210M27078
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CUL3 DST IQGAP2 LSG1 CYTH3 SYNE1 RIPK2 SMARCC1 RACGAP1 PARN ARHGEF26 HOMER3 CEP170B IQGAP1

1.98e-08963761428671696
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CUL3 RALGAPA1 EEF1D CPNE6 RAP1GAP DST IQGAP2 MYO7A UCHL1 SYNE1 ELP1 HOMER3 CEP170B DYNC1I1 OPHN1 IQGAP1

6.53e-081431761637142655
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

EEF1D ERCC5 TCERG1L DST IQGAP2 LSG1 SYNE1 SMARCC1 LSM14A APOB YBX3 CDK5R2 DYNC1I1 FER1L6 IQGAP1 CAPN11

7.25e-081442761635575683
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

CUL3 NCAPD3 RAP1GAP DST LSG1 ELP1 SMARCC1 RACGAP1 PARN DICER1 PLXNB1

1.70e-07650761138777146
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

CUL3 RALGAPA1 IQGAP2 SYNE1 DYNC1LI1 CEP170B DYNC1I1 IQGAP1

1.93e-0728176828706196
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CUL3 RALGAPA1 NCAPD3 DST CEP162 RACGAP1 PLXND1 DICER1 PLXNB1 IQGAP1

2.37e-07529761014621295
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

EEF1D CEBPA IQGAP2 SULT2A1 LSG1 UCHL1 ELP1 SMARCC1 RACGAP1 LSM14A APOB YBX3 DICER1 IQGAP1

1.43e-061371761436244648
Pubmed

Differential expression of IQGAP1/2 in Hepatocellular carcinoma and its relationship with clinical outcomes.

IQGAP2 IQGAP1

4.71e-06276224998570
Pubmed

IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma.

IQGAP2 IQGAP1

4.71e-06276220977743
Pubmed

Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent.

IQGAP2 IQGAP1

4.71e-06276218180285
Pubmed

A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.

DST SYNE1 CEP170B DYNC1I1

9.36e-066076420682791
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCAPD3 MYO7A MC3R ELP1 SMARCC1 ADCK2 SMCR8 HOMER3 FER1L6

1.06e-0563876931182584
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

NCAPD3 EEF1D LSG1 UCHL1 SYNE1 ELP1 SMARCC1 RACGAP1 DYNC1LI1 APOB YBX3 DICER1 IQGAP1

1.20e-051425761330948266
Pubmed

The biology of IQGAP proteins: beyond the cytoskeleton.

IQGAP2 IQGAP1

1.41e-05376225722290
Pubmed

IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold.

IQGAP2 IQGAP1

1.41e-05376222493426
Pubmed

Rip2 Is Required for Nod2-Mediated Lysozyme Sorting in Paneth Cells.

LRRK2 RIPK2

1.41e-05376228330897
Pubmed

Involvement of IQGAP family proteins in the regulation of mammalian cell cytokinesis.

IQGAP2 IQGAP1

1.41e-05376225229330
Pubmed

Dicer1 deletion in myeloid-committed progenitors causes neutrophil dysplasia and blocks macrophage/dendritic cell development in mice.

CEBPA DICER1

1.41e-05376222353998
Pubmed

LRRK2 and RIPK2 variants in the NOD 2-mediated signaling pathway are associated with susceptibility to Mycobacterium leprae in Indian populations.

LRRK2 RIPK2

1.41e-05376224015287
Pubmed

The Structural Basis for Cdc42-Induced Dimerization of IQGAPs.

IQGAP2 IQGAP1

1.41e-05376227524202
Pubmed

Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development.

IQGAP2 IQGAP1

2.82e-05476214516655
Pubmed

LRRK2 enhances Nod1/2-mediated inflammatory cytokine production by promoting Rip2 phosphorylation.

LRRK2 RIPK2

2.82e-05476227830463
Pubmed

Valosin-containing protein (VCP) is a novel IQ motif-containing GTPase activating protein 1 (IQGAP1)-interacting protein.

IQGAP2 IQGAP1

2.82e-05476228970065
Pubmed

Identification of a putative effector for Cdc42Hs with high sequence similarity to the RasGAP-related protein IQGAP1 and a Cdc42Hs binding partner with similarity to IQGAP2.

IQGAP2 IQGAP1

2.82e-0547628702968
Pubmed

The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding.

RACGAP1 PLXNB1

2.82e-05476211937491
Pubmed

SANS (USH1G) Molecularly Links the Human Usher Syndrome Protein Network to the Intraflagellar Transport Module by Direct Binding to IFT-B Proteins.

IFT52 IFT20

2.82e-05476231637240
Pubmed

Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.

DYNC1LI1 DYNC1I1

2.82e-05476219229290
Pubmed

Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice.

ABCC4 SULT2A1

2.82e-05476215004017
Pubmed

The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly.

IFT52 IFT20

2.82e-05476216775004
Pubmed

Mammalian chromatin remodeling complex SWI/SNF is essential for enhanced expression of the albumin gene during liver development.

CEBPA SMARCC1

2.82e-05476216452305
Pubmed

Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination.

CUL3 CHMP1B YBX3

2.82e-052776330442762
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

EXOC5 MYO7A CEP162 SYNE1 CLPTM1

3.47e-0516876530631154
Pubmed

Prenatal differentiation of mouse vomeronasal neurones.

UCHL1 CNDP1

4.69e-0557629753148
Pubmed

LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity.

CKM LRRK2

4.69e-05576217447891
Pubmed

Mutation analysis of LRRK2, SCNA, UCHL1, HtrA2 and GIGYF2 genes in Chinese patients with autosomal dorminant Parkinson's disease.

UCHL1 LRRK2

4.69e-05576222503729
Pubmed

Bile acids activate YAP to promote liver carcinogenesis.

IQGAP2 IQGAP1

4.69e-05576224268772
Pubmed

Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma.

DYNC1LI1 DYNC1I1

4.69e-05576230250299
Pubmed

Distinct PAR/IQGAP expression patterns during murine development: implications for thrombin-associated cytoskeletal reorganization.

IQGAP2 IQGAP1

4.69e-05576215457341
Pubmed

Identification and characterization of a 315-base pair enhancer, located more than 55 kilobases 5' of the apolipoprotein B gene, that confers expression in the intestine.

CEBPA APOB

4.69e-05576210859308
Pubmed

The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases.

IQGAP2 IQGAP1

4.69e-0557628756646
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

NCAPD3 EEF1D EXOC5 DST IQGAP2 ELP1 RACGAP1 DYNC1LI1 YBX3 DICER1 MX1 IQGAP1

6.47e-051440761230833792
Pubmed

Evaluation of Nod-like receptor (NLR) effector domain interactions.

NLRP12 RIPK2

7.03e-05676219337385
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

LSG1 DYNC1LI1 LSM14A LRRC8B HOMER3 OPHN1 IQGAP1

8.23e-0547576731040226
Pubmed

Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.

DST IFT20 LSM14A YBX3 CEP170B IQGAP1

8.58e-0532976634316702
Pubmed

The role of sensory organs and the forebrain for the development of the craniofacial shape as revealed by Foxg1-cre-mediated microRNA loss.

MYO7A DICER1

9.83e-05776221225654
Pubmed

IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia.

IFT52 IFT20

9.83e-05776212821668
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

STX2 NCAPD3 LSG1 UCHL1 DYNC1LI1 LSM14A APOB PLXND1 DICER1 CEP170B

1.03e-041061761033845483
Pubmed

HIV-1 uncoating is facilitated by dynein and kinesin 1.

DYNC1LI1 DYNC1I1

1.31e-04876225231297
Pubmed

Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily.

LRRK2 MFN1

1.31e-04876224282027
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

EEF1D DST MYO7A LRRK2 APOB YBX3 MFN1

1.32e-0451376725798074
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

CUL3 EXOC5 IFT52 IQGAP2 MYO7A IFT20 CLPTM1 DYNC1LI1 SNAPC1 DICER1 IQGAP1

1.35e-041321761127173435
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

CUL3 NCAPD3 EEF1D CEBPA SMARCC1 DYNC1LI1 CHD9 LSM14A HOMER3 IQGAP1

1.41e-041103761034189442
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

EEF1D DST SYNE1 SMARCC1 FER1L6

1.65e-0423476536243803
Pubmed

Linking cytoplasmic dynein and transport of Rab8 vesicles to the midbody during cytokinesis by the doublecortin domain-containing 5 protein.

DCDC1 DYNC1I1

1.68e-04976222159412
Pubmed

A highly conserved molecular switch binds MSY-3 to regulate myogenin repression in postnatal muscle.

CKM YBX3

1.68e-04976218676817
Pubmed

Inhibitory effects of kynurenic acid, a tryptophan metabolite, and its derivatives on cytosolic sulfotransferases.

SULT1C2 SULT2A1

1.68e-04976219548878
Pubmed

The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease.

LRRK2 IQGAP1

1.68e-04976221983832
Pubmed

Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases.

LSM14A YBX3

1.68e-04976219858291
Pubmed

Genomewide association study of leprosy.

LRRK2 RIPK2

1.68e-04976220018961
Pubmed

Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data.

EEF1D SYNE1 IQGAP1

2.05e-045276326499835
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

CUL3 IFT20 SYNE1 SMARCC1 RACGAP1 DYNC1LI1 LSM14A HOMER3 CEP170B IQGAP1

2.05e-041155761020360068
Pubmed

Inositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL function.

IPPK CUL3

2.10e-041076226976604
Pubmed

Signal transduction protein array analysis links LRRK2 to Ste20 kinases and PKC zeta that modulate neuronal plasticity.

LRRK2 RIPK2

2.10e-041076220949042
Pubmed

MicroRNA-183 family expression in hair cell development and requirement of microRNAs for hair cell maintenance and survival.

MYO7A DICER1

2.10e-041076221360794
Pubmed

Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects.

SULT1C2 SULT2A1

2.10e-041076211535246
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

EXOC5 IQGAP2 ELP1 SMARCC1 RACGAP1 DYNC1LI1 IQGAP1

2.26e-0456076735241646
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

CUL3 IQGAP2 CYTH3 SYNE1 HOMER3

2.29e-0425176527507650
Pubmed

Large-scale concatenation cDNA sequencing.

CUL3 STX2 NCAPD3 IFT20 ADCK2 DICER1 MFN1

2.47e-045687679110174
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

CUL3 NCAPD3 EXOC5 IQGAP2 RACGAP1 LSM14A YBX3 IQGAP1

2.53e-0475976835915203
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

CPB2 APOB PLXND1 PLXNB1 CNDP1

2.55e-0425776516335952
Pubmed

Do polymorphisms in the familial Parkinsonism genes contribute to risk for sporadic Parkinson's disease?

UCHL1 LRRK2

2.56e-041176219224617
Pubmed

Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure.

RACGAP1 IQGAP1

2.56e-041176225074804
Pubmed

The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability.

CUL3 SYNE1

2.56e-041176227621083
Pubmed

Genomic polymorphisms provide prognostic information in intermediate-risk acute myeloblastic leukemia.

ERCC5 SULT1C2

2.56e-041176216507781
Pubmed

Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes.

SULT1C2 SULT2A1

2.56e-04117629034160
Pubmed

Sulfotransferases: genetics and role in toxicology.

SULT1C2 SULT2A1

2.56e-041176210720750
Pubmed

A "double adaptor" method for improved shotgun library construction.

CUL3 STX2 NCAPD3 IFT20 ADCK2 DICER1 MFN1

2.63e-045747678619474
Pubmed

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.

CUL3 EXOC5 ELP1 SMARCC1 DYNC1I1 IQGAP1

2.86e-0441176636652389
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

DST IQGAP2 LSG1 CEP162 LRRK2 APOB PLXND1 SMCR8

2.96e-0477776835844135
Pubmed

Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity.

NLRP12 LRRC8B

3.07e-041276232277911
Pubmed

Interplay of BAF and MLL4 promotes cell type-specific enhancer activation.

CKM CEBPA

3.07e-041276233712604
Pubmed

Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.

PLXND1 PLXNB1

3.07e-041276221270798
Pubmed

IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade.

IQGAP2 IQGAP1

3.07e-041276218604197
Pubmed

MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.

DST ELP1 SMCR8 DICER1

3.35e-0415076422678362
Pubmed

The role of oxidative stress in Parkinson's disease.

UCHL1 LRRK2

3.62e-041376224252804
Pubmed

Intestinal maturation in mice lacking CCAAT/enhancer-binding protein alpha (C/EPBalpha).

CEBPA APOB

3.62e-04137629494081
Pubmed

Genetic dissection of the glutamatergic neuron system in cerebral cortex.

TCERG1L PLXND1

3.62e-041376234616069
Pubmed

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

PLXND1 PLXNB1

3.62e-041376210520995
Pubmed

Cytoplasmic dynein nomenclature.

DYNC1LI1 DYNC1I1

3.62e-041376216260502
Pubmed

The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.

IFT52 IFT20

3.62e-041376225443296
Pubmed

WD repeat-containing protein 5 (WDR5) localizes to the midbody and regulates abscission.

CHMP1B RACGAP1

3.62e-041376225666610
Pubmed

Structural and chemical profiling of the human cytosolic sulfotransferases.

SULT1C2 SULT2A1

3.62e-041376217425406
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

CUL3 NCAPD3 EEF1D SMARCC1 DYNC1LI1 CHD9 YBX3 IQGAP1

3.87e-0480976832129710
Pubmed

Identification of the hypoxia-inducible factor 2α nuclear interactome in melanoma cells reveals master proteins involved in melanoma development.

NCAPD3 ELP1 SMARCC1

4.16e-046676323275444
Pubmed

Allogeneic B cell immunomodulatory therapy in amyotrophic lateral sclerosis.

NLRP12 MX1

4.22e-041476238967302
Pubmed

Noradrenergic circuit control of non-REM sleep substates.

NLRP12 MX1

4.22e-041476234648731
Pubmed

Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse.

DYNC1LI1 DYNC1I1

4.22e-041476221471385
Pubmed

Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning.

NLRP12 MX1

4.22e-041476235665767
Pubmed

TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella.

IFT52 IFT20

4.22e-041476224596149
Pubmed

Early loss of cerebellar Purkinje cells in human and a transgenic mouse model of Alzheimer's disease.

NLRP12 MX1

4.22e-041476233688799
InteractionIFT57 interactions

EXOC5 IFT52 IFT20 SYNE1 TMCO3 HOMER3

1.38e-0693766int:IFT57
InteractionECPAS interactions

CCNF CUL3 CEBPA DST CYP2J2 SYNE1 CACNG4 CEP170B DYNC1I1

4.89e-06337769int:ECPAS
InteractionMETTL13 interactions

CCNF CUL3 SMARCC1 CACNG4 TMCO3

1.14e-0578765int:METTL13
InteractionDYNC1I1 interactions

CUL3 RAP1GAP DCDC1 DYNC1LI1 DYNC1I1 IQGAP1

1.42e-05139766int:DYNC1I1
InteractionAGAP2 interactions

RALGAPA1 IQGAP2 SYNE1 DYNC1LI1 CEP170B DYNC1I1 IQGAP1

1.44e-05210767int:AGAP2
InteractionMYH9 interactions

CCNF CUL3 EEF1D CEBPA DST CEP162 UCHL1 LRRK2 SMARCC1 CHD9 APOB IQGAP1

2.37e-057547612int:MYH9
InteractionABTB2 interactions

CUL3 CKM IFT52 IQGAP2 IFT20

3.99e-05101765int:ABTB2
InteractionZNF141 interactions

CUL3 CEBPA

4.20e-053762int:ZNF141
InteractionKCTD13 interactions

CUL3 RALGAPA1 EEF1D CPNE6 RAP1GAP DST IQGAP2 MYO7A UCHL1 SYNE1 ELP1 HOMER3 CEP170B DYNC1I1 OPHN1 IQGAP1

5.20e-0513947616int:KCTD13
InteractionMYCBP2 interactions

CCNF CUL3 CEBPA DST UCHL1 SMARCC1 LSM14A IQGAP1

5.69e-05355768int:MYCBP2
CytobandEnsembl 112 genes in cytogenetic band chr19q13

CKM NLRP12 CEBPA SULT2A1 CLPTM1 ZNF813 ZNF808 ZNF525 LSM14A

1.56e-041192769chr19q13
GeneFamilyPlexins

PLXND1 PLXNB1

2.56e-049492683
GeneFamilyDyneins, cytoplasmic

DYNC1LI1 DYNC1I1

5.51e-0413492538
GeneFamilySulfotransferases, cytosolic

SULT1C2 SULT2A1

6.41e-0414492762
GeneFamilyParkinson disease associated genes

UCHL1 LRRK2

8.43e-0416492672
GeneFamilyIntraflagellar transport proteins|Tetratricopeptide repeat domain containing

IFT52 IFT20

1.91e-0324492615
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP CEBPA SULT1C2 LRRK2 CPB2 PLXND1

3.79e-07164766b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP CEBPA SULT1C2 LRRK2 CPB2 PLXND1

3.79e-071647663aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCellfacs-Brain_Myeloid-Striatum_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NLRP12 SYNE1 LRRK2 PLXND1 IQGAP1

7.34e-061577659d4308312301cb922f156a7b6aededc9e1c62807
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNF STX2 NCAPD3 SYNE1 RACGAP1

1.46e-05181765566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNF STX2 NCAPD3 SYNE1 RACGAP1

1.46e-05181765db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

RALGAPA1 EXOC5 SMARCC1 LRRC8B SMCR8

1.99e-05193765abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP CEBPA SULT1C2 LRRK2 CPB2

2.14e-0519676582b117be41f2e7d677a42d2a5198726eeccb16d0
ToppCellLPS_IL1RA_TNF|World / Treatment groups by lineage, cell group, cell type

SYNE1 LRRK2 DYNC1LI1 CHD9 MX1

2.20e-051977650a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCellcontrol-HLA-DR+_CD83+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CEBPA DST YBX3 MX1 CAPN11

2.30e-05199765f1b370d2869ad29c9d8ff41fdcc486fffa781ee2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF813 ADCK2 DYNC1I1 CNDP1

8.91e-051377640c82f815c014d01213d23b466043d6e57186dceb
ToppCellASK454-Epithelial-Secretory|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CHMP1B ICE2 DYNC1LI1 CFAP157

1.08e-041447648e693b50bd6c69ce68f44ca6e51f6d0c7f80d82c
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma|TCGA-Uterus / Sample_Type by Project: Shred V9

CUL3 ABCC4 DST ZNF808

1.30e-041517642810bfa01bd3016aeba29735eb4a9284792e8aac
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCNF ERCC5 PLXND1 CAPN11

1.43e-04155764969fc4c98a96bf2f436e8e63d4deb2183ef3b864
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Serpinb1a_(Serpinb1a)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CKM NLRP12 APOB

1.48e-046076348adafeec1810bce5f118fa63d4a8ee7ab9ca0f7
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Serpinb1a_(Serpinb1a)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CKM NLRP12 APOB

1.48e-0460763a83afb89dbfc2e1cdfce57320d89c980bd8fb820
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 LRRK2 PLXND1 IQGAP1

1.62e-041607641f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNF NCAPD3 CEP162 RACGAP1

1.74e-041637643efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCK2 CDK5R2 HOMER3 CEP170B

1.74e-04163764953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DST IQGAP2 ARHGEF26 DYNC1I1

1.95e-04168764315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DST IQGAP2 ARHGEF26 DYNC1I1

1.95e-04168764e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCNF NCAPD3 SULT2A1 RACGAP1

2.00e-04169764e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TCERG1L IQGAP2 SYNE1 IQGAP1

2.00e-04169764f06118754fa62c580b4bcbecff6f9e5fdc2106a0
ToppCellP28-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CKM CEBPA LRRK2 APOB

2.04e-04170764d0ed3a8a7ad96c05641ec409b0a69c4fb094893c
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNF STX2 NCAPD3 RACGAP1

2.09e-04171764913bae728b5e653771a27c79a309eb023699f1d0
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNF STX2 NCAPD3 RACGAP1

2.09e-04171764f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell343B-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

LSG1 RIPK2 ZNF813 MFN1

2.14e-04172764eb199c279fe8a2551121db37e9556893197d33ff
ToppCelldroplet-Marrow-nan-3m-Hematologic-proerythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 LRRK2 ELP1 IQGAP1

2.14e-04172764cfcfa7eeff1805bedf10a3c07826459914c3e872
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DST IQGAP2 ARHGEF26 DYNC1I1

2.14e-041727646c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell343B-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

LSG1 RIPK2 ZNF813 MFN1

2.14e-04172764709c6b77a7a52b873eefb6caca28a41291d384af
ToppCell3'_v3-bone_marrow-Lymphocytic_B-GC_B_(I)|bone_marrow / Manually curated celltypes from each tissue

CCNF CPNE6 SULT1C2 LRRC8B

2.18e-0417376467f0f0bf88eab69987b71d96b864ed2b14975adb
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

MYO7A PLXND1 HOMER3 PLXNB1

2.38e-04177764470f54fe2b21c7350ea471e02039461a3808f700
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DST IQGAP2 ARHGEF26 DYNC1I1

2.49e-041797647394e77e665bf16d3733df91bb12907be460ab44
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCAPD3 ZNF808 ZNF525 ADCK2

2.49e-0417976406d412fc096d88de168969466ce422f0ab5553b2
ToppCell10x5'-bone_marrow-Myeloid_Mac-Macrophage|bone_marrow / Manually curated celltypes from each tissue

ABCC4 CEBPA DST HOMER3

2.59e-04181764d2aa5b53162fb5c4cbbedbd2cb4b2b614e8c4afa
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DST IQGAP2 ARHGEF26 DYNC1I1

2.59e-041817645bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DST IQGAP2 ARHGEF26 DYNC1I1

2.59e-041817648e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

TCERG1L UCHL1 CDK5R2 DYNC1I1

2.65e-0418276457bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNF NCAPD3 SYNE1 RACGAP1

2.65e-041827649025178ede571e3808d4657ad4892152f336c9b4
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNF NCAPD3 SYNE1 RACGAP1

2.65e-04182764c075756cd4bb484ede1be2bcdb9eac60eab0573a
ToppCellBAL-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SULT1C2 MYO7A UCHL1 HOMER3

2.70e-041837648e9d45c96b44558158e3d59613f64a73d5390c19
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SULT1C2 MYO7A UCHL1 HOMER3

2.70e-041837640408d991ddb639594b45d5cb2432dd29289167b1
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SULT1C2 MYO7A UCHL1 HOMER3

2.70e-0418376479f05b8a967124d831b0baef137e30659f5917a7
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP SULT1C2 LRRK2 CPB2

2.76e-041847640ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SULT1C2 MYO7A UCHL1 HOMER3

2.76e-0418476492202e1cd0bba1ce4b061ebcb8a2af5bb590542a
ToppCellBAL-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SULT1C2 MYO7A UCHL1 HOMER3

2.76e-041847647331535d469453a5264dcb0270a97f63d3b55201
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP SULT1C2 LRRK2 CPB2

2.76e-041847642a8338e94937686a148b5433515700ca0f674058
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SULT1C2 MYO7A UCHL1 HOMER3

2.76e-04184764337e38a6b2b6770cc992d88b006829f194841b10
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DST IQGAP2 ARHGEF26 DYNC1I1

2.82e-041857649197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DST IQGAP2 ARHGEF26 DYNC1I1

2.82e-04185764ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DST IQGAP2 ARHGEF26 DYNC1I1

2.82e-04185764b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma|TCGA-Prostate / Sample_Type by Project: Shred V9

ABCC4 RAP1GAP RIPK2 ARHGEF26

2.82e-041857649d53e0a92e4f99370be2e4be1dd737630796b1ca
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|lymph-node_spleen / Manually curated celltypes from each tissue

CCNF CEBPA DST RACGAP1

2.88e-0418676417eec1efad1f5e9ced1eb6bc9eb5dd7ded789c61
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SULT2A1 CPB2 APOB YBX3

2.94e-04187764edb0ab0154542b1c0b3a2c216c4a60f0f06290b3
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB13 RACGAP1 DYNC1I1 MX1

2.94e-04187764a6a112689d1c9049f57935ad9d2f4955538427de
ToppCell343B-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

EXOC5 MYO7A CEP162 LRRC8B

3.06e-04189764c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

RAP1GAP CEBPA LRRK2 CPB2

3.06e-041897642d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EEF1D ABCC4 LRRK2 YBX3

3.06e-04189764bd91bdfe35294e60d980259b70fe9e60dca2743f
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNF IQGAP2 RACGAP1 CACNG4

3.12e-04190764b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

DST CACNG4 HOMER3 DYNC1I1

3.12e-04190764842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD9 APOB YBX3 IQGAP1

3.18e-0419176460c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellControl-Myeloid-transitional_Macro|Control / Disease group,lineage and cell class (2021.01.30)

SULT1C2 MYO7A UCHL1 HOMER3

3.18e-041917643ed0b1ff628a165e3c92c2e493206015f57dccfe
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD9 APOB YBX3 IQGAP1

3.18e-0419176409db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD9 APOB YBX3 IQGAP1

3.18e-04191764973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellThalamus-Neuronal|Thalamus / BrainAtlas - Mouse McCarroll V32

SPAG4 UCHL1 CDK5R2 DYNC1I1

3.31e-04193764712a4acd1167e43543950bc819ff11984e6f718d
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 LRRK2 CPB2 CFAP157

3.31e-04193764bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellControl-Classical_Monocyte|Control / Disease condition and Cell class

NLRP12 LRRK2 PLXND1 HOMER3

3.37e-041947649e33e1b54b4114f9e6981819834bb796ed7192b5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 DCDC1 SYNE1 LRRK2

3.37e-04194764e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IQGAP2 PLXND1 HOMER3 IQGAP1

3.37e-0419476448c37251518f96524807b5bd1bbc2820637666ad
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IQGAP2 PLXND1 HOMER3 IQGAP1

3.37e-041947647b6a34d1f8922b71dcc931421666c1822cec8345
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IQGAP2 PLXND1 HOMER3 IQGAP1

3.37e-04194764435406ebe626c702f7d5a99a3d68ee85aa09be95
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CEBPA SULT1C2 SULT2A1 APOB

3.37e-04194764fcbf9c4f3801ab1a34fcd62c752fabc97fc7bde1
ToppCellnormal_Lung-Epithelial_cells-AT2|Epithelial_cells / Location, Cell class and cell subclass

EEF1D CEBPA LRRK2 CPB2

3.44e-0419576481e13fe337f1d0a83d0deb86a0df797d306cd24d
ToppCellAT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

SULT1C2 SYNE1 LRRK2 CPB2

3.44e-04195764b0cea3f4e59635913d243612f2e8cf4c7b34e726
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC4 SERPINB13 CYP2J2 FER1L6

3.44e-04195764e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP SYNE1 LRRK2 CPB2

3.44e-0419576437aa6e4123d37de4de42ca68d3020f2a7686ce02
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNF NCAPD3 SMARCC1 RACGAP1

3.44e-04195764043e2f19d95e94cd5219e2c415f322ed340aa80f
ToppCell3'-Parenchyma_lung-Epithelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP SYNE1 LRRK2 CPB2

3.44e-04195764eec187c087e432417bc346c5d3ead72f58bf3215
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP SYNE1 LRRK2 CPB2

3.51e-041967647e5addaa844e66f8160e05858c341866a80aed23
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TCERG1L SULT2A1 CACNG4 ARHGEF26

3.51e-04196764b74dbdfc8d9b85d7cae5c6a49b56347b15ce16e1
ToppCellmLN-T_cell-gd_T|T_cell / Region, Cell class and subclass

TCERG1L ZNF525 ARHGEF26 PLXNB1

3.51e-041967648f476408cd5a4ea9d25c763c66565343d7989b38
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCC4 CEBPA MYO7A MX1

3.51e-04196764e54c08f88779f9fd453a4f5b85aed1f460d8a1e1
ToppCelldistal-Epithelial-Goblet|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB13 CYP2J2 FER1L6 CNDP1

3.58e-04197764da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|Epithelial / Condition, Lineage and Cell class

SERPINB13 CYP2J2 FER1L6 OPHN1

3.58e-0419776478ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCellCOVID-granulo1-|COVID / Condition, Cell_class and T cell subcluster

NLRP12 LRRK2 YBX3 HOMER3

3.58e-04197764190392117dc6269a21983bd3e554066fd48acd5e
ToppCellmLN-(1)_T_cell-(17)_gd_T|mLN / shred on region, Cell_type, and subtype

TCERG1L ZNF525 ARHGEF26 PLXNB1

3.58e-041977645c781ded147db2f3804ee1f21ef0898c4f354890
ToppCellCOVID-granulo1|COVID / Condition, Cell_class and T cell subcluster

NLRP12 LRRK2 YBX3 HOMER3

3.58e-041977644cd774d9d5a6bf7729dc6b7bcd3ddfe3f3051ada
ToppCelldistal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB13 CYP2J2 FER1L6 CNDP1

3.58e-04197764a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCellmLN-(2)_B_cell-(20)_B_cell_IgA_Plasma|mLN / shred on region, Cell_type, and subtype

SPAG4 HOMER3 NXPH3 CEP170B

3.58e-04197764a39b384ee9824a08c3b544a9c3c7f0f95f08d6a7
ToppCellmLN-T_cell-gd_T|mLN / Region, Cell class and subclass

TCERG1L ZNF525 ARHGEF26 PLXNB1

3.58e-041977648ef03bdbd34a874671aebfdbb7111106aa37b2a9
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAP1GAP SYNE1 LRRK2 CPB2

3.58e-04197764bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCelltumor_Lung-Epithelial_cells-tS1|Epithelial_cells / Location, Cell class and cell subclass

CEBPA SYNE1 LRRK2 CPB2

3.58e-041977647190143468939cf26c069d125a5e88e4bf026299
ToppCellmLN-B_cell-B_cell_IgA_Plasma|mLN / Region, Cell class and subclass

SPAG4 HOMER3 NXPH3 CEP170B

3.58e-0419776420822fce311326765b71337ce501ba44ea14f58f
ToppCelldistal-Epithelial-Goblet-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB13 CYP2J2 FER1L6 CNDP1

3.58e-041977643fbf456ae4f73da4f6254a6f0d24f0ec27d7a3cc
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CEBPA SULT1C2 SULT2A1 APOB

3.64e-04198764686d973483d027a3ffa2ad4430ba6e50f3d1378e
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CEBPA SULT1C2 SULT2A1 APOB

3.64e-041987647696f042648bd53c0a019dfeea68808aa5898615
ToppCellBiopsy_Other_PF-Epithelial-MUC5AC+_High|Biopsy_Other_PF / Sample group, Lineage and Cell type

SERPINB13 CYP2J2 APOB FER1L6

3.64e-0419876430e6177e216f66caddcd009fafef0e07369f4d8e
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CEBPA SULT1C2 SULT2A1 APOB

3.64e-04198764ecdef1a0a0b8399e193b922c8ca8c25e63de4a4f
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CEBPA SULT1C2 SULT2A1 APOB

3.64e-04198764a76366611f3561fc8aca7d62d1f0a0ea2bef7792
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CEBPA SULT1C2 SULT2A1 APOB

3.64e-04198764e67488695ce5e32ed8d149ed0b841540cbfdd3e2
ToppCellCOVID-19_Mild-Classical_Monocyte|COVID-19_Mild / Disease condition and Cell class

NLRP12 LRRK2 PLXND1 HOMER3

3.64e-0419876430ada3de865b6fb2b14196a1cbfd4740c6a57ce3
Drughippuryl-L-lysine

CKM CPB2 CNDP1

2.35e-0517763CID000098208
DrugCuCl2

CCNF CUL3 ASB18 DST

3.19e-0554764CID000024014
Drug5-Br

SYNE1 CPB2 MX1

3.91e-0520763CID000008057
DrugMepenzolate bromide [76-90-4]; Down 200; 9.6uM; PC3; HT_HG-U133A

RALGAPA1 STX2 SMARCC1 DICER1 HOMER3 IQGAP1

4.08e-051897664304_DN
DrugMethylergometrine maleate [113-42-8]; Down 200; 8.8uM; PC3; HT_HG-U133A

RALGAPA1 EXOC5 ADCK2 DICER1 HOMER3 MFN1

4.58e-051937666704_DN
DrugTrimipramine maleate salt [521-78-8]; Down 200; 9.8uM; MCF7; HT_HG-U133A

TMPRSS15 UCHL1 SMARCC1 TMCO3 DICER1 HOMER3

4.72e-051947664163_DN
DrugRolipram [61413-54-5]; Down 200; 14.6uM; MCF7; HT_HG-U133A

CUL3 CEBPA CACNG4 HOMER3 PLXNB1 MFN1

4.72e-051947665330_DN
DrugZardaverine [101975-10-4]; Up 200; 15uM; MCF7; HT_HG-U133A

RALGAPA1 STX2 UCHL1 TMCO3 DICER1 HOMER3

4.72e-051947667347_UP
DrugFenofibrate [49562-28-9]; Down 200; 11uM; MCF7; HT_HG-U133A

STX2 ZNF813 PLXND1 TMCO3 HOMER3 PLXNB1

4.86e-051957667432_DN
DrugPerhexiline maleate [6724-53-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A

CUL3 STX2 CYP2J2 PLXND1 HOMER3 PLXNB1

4.86e-051957667441_DN
DrugFenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A

SPAG4 CEP162 CACNG4 TMCO3 HOMER3 MFN1

4.86e-051957663721_DN
DrugCyclopenthiazide [742-20-1]; Down 200; 10.6uM; MCF7; HT_HG-U133A

EXOC5 CHMP1B RIPK2 LSM14A TMCO3 IQGAP1

5.00e-051967664813_DN
Drug3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; PC3; HT_HG-U133A

CUL3 RALGAPA1 MYO7A MC3R APOB HOMER3

5.00e-051967664664_UP
DrugMethionine sulfoximine (L) [15985-39-4]; Down 200; 22.2uM; MCF7; HT_HG-U133A

SPAG4 UCHL1 ELP1 ADCK2 CPB2 MX1

5.00e-051967664151_DN
DrugPNU-0251126 [267429-19-6]; Up 200; 1uM; PC3; HT_HG-U133A

TMPRSS15 SERPINB13 SULT1C2 CYTH3 ADCK2 CPB2

5.00e-051967663692_UP
Drugnordihydroguaiaretic acid; Up 200; 1uM; ssMCF7; HG-U133A

EXOC5 CYP2J2 CACNG4 ARHGEF26 DYNC1I1 IQGAP1

5.14e-05197766415_UP
DrugClindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; PC3; HT_HG-U133A

CUL3 TMPRSS15 LSM14A CACNG4 PLXND1 HOMER3

5.29e-051987662057_UP
Drug(R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; HL60; HT_HG-U133A

STX2 CKM TMPRSS15 RIPK2 MC3R CACNG4

5.29e-051987662496_UP
DrugTrichlormethiazide [133-67-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A

ABCC4 SPAG4 RIPK2 ARHGEF26 HOMER3 PLXNB1

5.59e-052007664783_DN
Diseaseprotein-tyrosine kinase 2-beta measurement

NLRP12 APOB

3.61e-054732EFO_0801969
Diseaseannexin A2 measurement

NLRP12 ICE2

1.26e-047732EFO_0008027
Diseasefibrinogen measurement, tissue plasminogen activator measurement

STX2 CHD9 PLXND1

1.91e-0445733EFO_0004623, EFO_0004791
DiseaseLiver carcinoma

CCNF CEBPA IQGAP2 UCHL1 RACGAP1 IQGAP1 CNDP1

2.60e-04507737C2239176
Diseaseargininosuccinate measurement

ABCC4 MC3R

3.27e-0411732EFO_0010461
DiseaseMAP kinase-activated protein kinase 3 measurement

NLRP12 CPB2

4.63e-0413732EFO_0008226
Diseasecopine-1 measurement

NLRP12 SPAG4

8.02e-0417732EFO_0008102
DiseaseDiGeorge syndrome (implicated_via_orthology)

PLXND1 DICER1

1.00e-0319732DOID:11198 (implicated_via_orthology)
DiseaseParkinson disease

UCHL1 LRRK2

1.35e-0322732cv:C0030567
Diseasepulmonary embolism

ABCC4 ZNF808

1.75e-0325732EFO_0003827
DiseaseAlzheimer disease, high density lipoprotein cholesterol measurement

CLPTM1 APOB

1.89e-0326732EFO_0004612, MONDO_0004975
Diseaseobesity (implicated_via_orthology)

MC3R PLXND1 PLXNB1 CAPN11

2.01e-03215734DOID:9970 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
EHFQVNFRNVKAVKF

ADCK2

371

Q7Z695
FFLVDFEQSHLEVQL

CYP2J2

56

P51589
KFFIELEARHQNNIF

ARHGEF26

496

Q96DR7
ELLHNQQAFVIEFFD

CEP170B

396

Q9Y4F5
EFQNIQDVHLKKEFF

CAPN11

476

Q9UMQ6
FHVIDDFVQFQLEKN

DICER1

1766

Q9UPY3
HFFTQVFQDLKNEGE

CDK5R2

316

Q13319
KDAFEAQLAQVRHEF

CFAP157

116

Q5JU67
FEEHVQSVDIAAFNK

EEF1D

266

P29692
FEEKQPLQFHVFDAE

CPNE6

81

O95741
KFVHLLDQSDQDFQE

IQGAP1

871

P46940
EEIFQHLQNIVDFGK

IPPK

46

Q9H8X2
QEADLQVDKERHNFF

OPHN1

161

O60890
NLHKVYQAIEEADFF

PARN

11

O95453
HARLQEFQNFEQIFE

MFN1

311

Q8IWA4
DKFEHQFETLDVQTQ

CHMP1B

116

Q7LBR1
DQFEKVDLENHFLQN

DCDC1

646

M0R2J8
KQIENIVDKTFFHQE

LSG1

586

Q9H089
VLFQIDEHKVFANEV

DST

6631

Q03001
FFQDANVVFEINKDE

ASB18

81

Q6ZVZ8
GKNIQLHFQEFDLEN

TMPRSS15

561

P98073
KQQILHSEEFLIFFD

DYNC1I1

221

O14576
LHENFQTLKAEDNFE

DYNC1LI1

336

Q9Y6G9
EQHLTQFAEKFQEVK

HOMER3

96

Q9NSC5
VKYFFDLLDEQAQQH

PLXNB1

1951

O43157
FVHALEQQKDFAVRD

PLXND1

1426

Q9Y4D7
NFFNILVLNEVHEFV

LRRK2

281

Q5S007
ANAQFNKEEIDREFH

LSM14A

301

Q8ND56
NQQDIVFFEKNGLLH

ELP1

261

O95163
DVKNDFAFILHLADQ

LRRC8B

361

Q6P9F7
DVNKFDQVTVFLHFL

ABCC4

201

O15439
VQQANTIFHLFDKQF

EXOC5

486

O00471
LHKFNEFIQNELQEA

APOB

4356

P04114
TDFEQLNQFDSIKFH

CHD9

66

Q3L8U1
FFQVVEFKKLNQEHD

IFT52

411

Q9Y366
HVNEEVTEFLKFLQN

ICE2

141

Q659A1
KQVHFFVNASDVDNV

CPB2

66

Q96IY4
LFEDEEKQQQAHDLF

CCNF

196

P41002
QEASFLQVHDFFQQD

CACNG4

296

Q9UBN1
LQVHDFFQQDLKEGF

CACNG4

301

Q9UBN1
EFLADLFQHSRQQEK

CEBPA

76

P49715
KEIENGHIFTVNDQF

CUL3

651

Q13618
FNIKVLQAFVELHEF

CYTH3

126

O43739
HVNLFFDKNDENVIL

CEP162

401

Q5TB80
FQSIEFQVEQAHAKA

CEP162

1071

Q5TB80
LTFEDQFIQHMDNIF

MC3R

106

P41968
KVEAEQNEFIDQFIF

IFT20

116

Q8IY31
EFHQEQQIFIEAKAS

NXPH3

156

O95157
HEAQNFVEKIRFLVD

FER1L6

696

Q2WGJ9
DEEKLFQVHTFEIFQ

TMCO3

86

Q6UWJ1
FQVHTFEIFQKELNE

TMCO3

91

Q6UWJ1
FFLHELGEQLKQQVD

SYNE1

7301

Q8NF91
EKEQQQLIDDHFLFD

CKM

181

P06732
FLHEQEENVVKIQAF

IQGAP2

686

Q13576
ENVVSFNAKEHENFL

ERCC5

601

P28715
FNAKEHENFLETIQE

ERCC5

606

P28715
IVTFDEHVISNNFKF

RAP1GAP

181

P47736
NHFTVAQAEDFDKLF

SULT2A1

256

Q06520
NEVQFIQLAKDFEDF

RACGAP1

26

Q9H0H5
VVQLLQFQEDAFGKH

SMARCC1

81

Q92922
FDVEKSEIQTFHLQN

SPAG4

376

Q9NPE6
DFFHQVEEIRNSIDK

STX2

31

P32856
LLKQQHITNFLFEDF

SMCR8

361

Q8TEV9
EVLKFQQDLVNAQHF

SNAPC1

106

Q16533
DFFDNIKNIVLEHQQ

SNAPC1

211

Q16533
VHSVFEFLAFKNDIQ

CLPTM1

366

O96005
KFLLEHFTDEQRFNI

NCAPD3

1101

P42695
EKVFQYIDLHQDEFV

CNDP1

36

Q96KN2
SFQEIEKDIHNFEFQ

ZNF525

86

Q8N782
KRKDQEHFFNQFILI

TCERG1L

556

Q5VWI1
FINRNDTKEDVFVHQ

YBX3

106

P16989
ENAESIDLKQFFDQH

RALGAPA1

36

Q6GYQ0
IENTEAVHQQFQKFL

SERPINB13

76

Q9UIV8
NILLDNEFHVKIADF

RIPK2

151

O43353
KNHFTVAQNERFDEI

SULT1C2

266

O00338
FCFQEIEKEIHNIEF

ZNF808

101

Q8N4W9
RFQEIDKDIHNLEFQ

ZNF813

86

Q6ZN06
DKVNFHFILFNNVDG

UCHL1

156

P09936
QEEEFIQQALSHFQV

NLRP12

621

P59046
DVSIKNFEEFFNLHR

MX1

486

P20591
LQQFFVRHVFKLEQE

MYO7A

461

Q13402