Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	endopeptidase inhibitor activity	CPAMD8 SPOCK2 APLP2 BIRC6 TIMP2 WFDC2 CST3 SERPING1	2.13e-05	180	128	8	GO:0004866
GeneOntologyMolecularFunction	peptidase inhibitor activity	CPAMD8 SPOCK2 APLP2 BIRC6 TIMP2 WFDC2 CST3 SERPING1	2.80e-05	187	128	8	GO:0030414
GeneOntologyMolecularFunction	endopeptidase regulator activity	CPAMD8 SPOCK2 APLP2 BIRC6 TIMP2 WFDC2 CST3 SERPING1	4.67e-05	201	128	8	GO:0061135
GeneOntologyMolecularFunction	amyloid-beta binding	EPHB2 GRIA4 CST3 LRP1 NGFR LRPAP1	5.02e-05	102	128	6	GO:0001540
GeneOntologyMolecularFunction	glycosaminoglycan binding	COL5A3 APLP1 SPOCK2 APLP2 APOB SUSD5 FGFBP3 LRPAP1 CXCL6	5.86e-05	268	128	9	GO:0005539
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP1B LRP10 LRP1	1.36e-04	16	128	3	GO:0005041
GeneOntologyMolecularFunction	heparin binding	COL5A3 APLP1 APLP2 APOB FGFBP3 LRPAP1 CXCL6	2.42e-04	192	128	7	GO:0008201
GeneOntologyMolecularFunction	peptidase regulator activity	CPAMD8 SPOCK2 APLP2 BIRC6 TIMP2 WFDC2 CST3 SERPING1	2.56e-04	257	128	8	GO:0061134
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LRP1B LRP10 LRP1	3.14e-04	21	128	3	GO:0030228
GeneOntologyMolecularFunction	lipase binding	APOB LRPAP1	8.38e-04	7	128	2	GO:0035473
GeneOntologyMolecularFunction	peptide binding	EPHB2 HLA-A HLA-H GRIA4 CST3 LRP1 NGFR LRPAP1	1.04e-03	318	128	8	GO:0042277
GeneOntologyMolecularFunction	MHC class I protein binding	HLA-A HLA-H CD8A	1.11e-03	32	128	3	GO:0042288
GeneOntologyMolecularFunction	sulfur compound binding	COL5A3 APLP1 APLP2 APOB FGFBP3 LRP1 LRPAP1 CXCL6	1.15e-03	323	128	8	GO:1901681
GeneOntologyMolecularFunction	coreceptor activity	LBP CD8A LRP1 NGFR	1.18e-03	72	128	4	GO:0015026
GeneOntologyMolecularFunction	CD8 receptor binding	HLA-A HLA-H	1.43e-03	9	128	2	GO:0042610
GeneOntologyMolecularFunction	TAP complex binding	HLA-A HLA-H	1.43e-03	9	128	2	GO:0062061
GeneOntologyMolecularFunction	TAP1 binding	HLA-A HLA-H	1.77e-03	10	128	2	GO:0046978
GeneOntologyMolecularFunction	TAP2 binding	HLA-A HLA-H	1.77e-03	10	128	2	GO:0046979
GeneOntologyMolecularFunction	TAP binding	HLA-A HLA-H	1.77e-03	10	128	2	GO:0046977
GeneOntologyMolecularFunction	lipoprotein particle receptor binding	APOB LRP1 LRPAP1	1.99e-03	39	128	3	GO:0070325
GeneOntologyBiologicalProcess	regulation of peptidase activity	DPEP1 PIDD1 SPOCK2 RET BIRC6 TIMP2 WFDC2 CST3 LRP1 NGFR SERPING1 EIF2AK3	9.47e-06	406	129	12	GO:0052547
GeneOntologyBiologicalProcess	regulation of body fluid levels	EPHB2 CAD DGKQ TYRO3 BTC HPS1 ENTPD2 SERPING1 SCT HSD11B2 EIF2AK3 SLC4A9	2.20e-05	442	129	12	GO:0050878
GeneOntologyCellularComponent	cell surface	EPHB2 ISLR2 HLA-A VASN HLA-H TSPEAR TSHR LBP BTN2A1 TYRO3 CD8A TIMP2 ENTPD2 BTN2A3P TNFRSF13C LRP1 NGFR LRPAP1 CDH2 BTNL9 CXCR2	3.36e-06	1111	127	21	GO:0009986
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	DPAGT1 ATG9B HLA-A ESYT1 LPCAT4 HLA-H RHBDD2 CASQ1 APOB ZDHHC1 TYRO3 ESYT2 LMF2 NUP210 ENTPD2 HSD11B2 FITM1 TMEM109 EIF2AK3 TNPO3 SLC27A5 RIC3	1.53e-05	1327	127	22	GO:0042175
GeneOntologyCellularComponent	endoplasmic reticulum membrane	DPAGT1 ATG9B HLA-A ESYT1 LPCAT4 HLA-H RHBDD2 CASQ1 APOB ZDHHC1 TYRO3 ESYT2 LMF2 NUP210 ENTPD2 HSD11B2 FITM1 TMEM109 EIF2AK3 SLC27A5 RIC3	3.33e-05	1293	127	21	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	DPAGT1 ATG9B HLA-A ESYT1 LPCAT4 HLA-H RHBDD2 CASQ1 APOB ZDHHC1 TYRO3 ESYT2 LMF2 NUP210 ENTPD2 HSD11B2 FITM1 TMEM109 EIF2AK3 SLC27A5 RIC3	3.56e-05	1299	127	21	GO:0098827
GeneOntologyCellularComponent	extracellular matrix	VASN COL5A3 APLP1 SPOCK2 TGFBI MEGF6 TIMP2 FGFBP3 ENTPD2 CST3 SERPING1 MMP14 CDH2	1.82e-04	656	127	13	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	VASN COL5A3 APLP1 SPOCK2 TGFBI MEGF6 TIMP2 FGFBP3 ENTPD2 CST3 SERPING1 MMP14 CDH2	1.88e-04	658	127	13	GO:0030312
GeneOntologyCellularComponent	terminal bouton	CAD DRD4 GRIA4 NMU NPY	3.01e-04	96	127	5	GO:0043195
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL5A3 APLP1 SPOCK2 TGFBI MEGF6 TIMP2 FGFBP3 ENTPD2 CST3 SERPING1 CDH2	3.95e-04	530	127	11	GO:0062023
GeneOntologyCellularComponent	cell body	EPHB2 CAD DRD4 GRIA4 APOB RET CNNM1 TIMP2 VPS35 ENTPD2 CST3 LRP1 NGFR NPY RIC3	5.22e-04	929	127	15	GO:0044297
GeneOntologyCellularComponent	neuronal cell body	EPHB2 CAD DRD4 GRIA4 APOB RET CNNM1 TIMP2 VPS35 CST3 LRP1 NGFR NPY RIC3	5.59e-04	835	127	14	GO:0043025
GeneOntologyCellularComponent	endosome	ATG9B HLA-A TMEM175 HLA-H DGKQ APOB RET ZDHHC1 BIRC6 VPS35 GZMB CST3 LRP1 NGFR CD68 LRPAP1 MMP14	7.04e-04	1167	127	17	GO:0005768
GeneOntologyCellularComponent	MHC class Ib protein complex	HLA-A HLA-H	7.54e-04	7	127	2	GO:0032398
GeneOntologyCellularComponent	basement membrane	APLP1 TGFBI TIMP2 ENTPD2 CST3	8.99e-04	122	127	5	GO:0005604
GeneOntologyCellularComponent	endoplasmic reticulum lumen	CASQ1 COL5A3 APLP2 APOB CST3 SERPING1 LRPAP1 CDH2	9.71e-04	332	127	8	GO:0005788
GeneOntologyCellularComponent	external side of plasma membrane	HLA-A HLA-H BTN2A1 CD8A BTN2A3P TNFRSF13C LRP1 NGFR BTNL9 CXCR2	1.28e-03	519	127	10	GO:0009897
GeneOntologyCellularComponent	vacuole	ATG9B HLA-A VASN ACP5 TMEM175 HLA-H APOB IDUA VPS35 HPS1 GZMB LRP1 CD68 CXCR2	1.32e-03	913	127	14	GO:0005773
GeneOntologyCellularComponent	lysosome	HLA-A VASN ACP5 TMEM175 HLA-H APOB IDUA VPS35 HPS1 GZMB LRP1 CD68 CXCR2	1.33e-03	811	127	13	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	HLA-A VASN ACP5 TMEM175 HLA-H APOB IDUA VPS35 HPS1 GZMB LRP1 CD68 CXCR2	1.33e-03	811	127	13	GO:0000323
GeneOntologyCellularComponent	MHC class I protein complex	HLA-A HLA-H	1.60e-03	10	127	2	GO:0042612
GeneOntologyCellularComponent	endocytic vesicle membrane	HLA-A HLA-H GRIA4 APOB BTC LRP1	1.89e-03	212	127	6	GO:0030666
GeneOntologyCellularComponent	endoplasmic reticulum exit site	HLA-A HLA-H APOB	2.11e-03	42	127	3	GO:0070971
GeneOntologyCellularComponent	basal part of cell	CNNM2 TSHR CLDN11 LRP1 CDH2 SLC4A9 SLC27A5 SLC16A10	2.20e-03	378	127	8	GO:0045178
GeneOntologyCellularComponent	side of membrane	DPEP1 HLA-A HLA-H BTN2A1 ESYT2 CD8A BTN2A3P TNFRSF13C LRP1 NGFR LY6E BTNL9 CXCR2	2.59e-03	875	127	13	GO:0098552
GeneOntologyCellularComponent	MHC class I peptide loading complex	HLA-A HLA-H	3.18e-03	14	127	2	GO:0042824
Domain	DUF21	CNNM2 CNNM3 CNNM1	1.16e-06	4	125	3	IPR002550
Domain	DUF21	CNNM2 CNNM3 CNNM1	1.16e-06	4	125	3	PF01595
Domain	DUF5050	LRP1B LRP1	4.44e-05	2	125	2	IPR032485
Domain	DUF5050	LRP1B LRP1	4.44e-05	2	125	2	PF16472
Domain	Amyloid_glyco_E2_domain	APLP1 APLP2	1.33e-04	3	125	2	IPR024329
Domain	A4_EXTRA	APLP1 APLP2	1.33e-04	3	125	2	PS00319
Domain	SMP_LBD	ESYT1 ESYT2	1.33e-04	3	125	2	PF17047
Domain	Amyloid_glyco_heparin-bd	APLP1 APLP2	1.33e-04	3	125	2	IPR015849
Domain	A4_INTRA	APLP1 APLP2	1.33e-04	3	125	2	PS00320
Domain	-	APLP1 APLP2	1.33e-04	3	125	2	3.90.570.10
Domain	SMP_LBD	ESYT1 ESYT2	1.33e-04	3	125	2	IPR031468
Domain	APP_N	APLP1 APLP2	1.33e-04	3	125	2	PF02177
Domain	APP_Cu_bd	APLP1 APLP2	1.33e-04	3	125	2	PF12924
Domain	APP_E2	APLP1 APLP2	1.33e-04	3	125	2	PF12925
Domain	APP_amyloid	APLP1 APLP2	1.33e-04	3	125	2	PF10515
Domain	Amyloid_glyco	APLP1 APLP2	1.33e-04	3	125	2	IPR008155
Domain	Amyloid_glyco_extra	APLP1 APLP2	1.33e-04	3	125	2	IPR008154
Domain	-	APLP1 APLP2	1.33e-04	3	125	2	3.30.1490.140
Domain	APP_amyloid_C	APLP1 APLP2	1.33e-04	3	125	2	IPR019543
Domain	Amyloid_glyco_extracell_CS	APLP1 APLP2	1.33e-04	3	125	2	IPR019744
Domain	Amyloid_glyco_intracell_CS	APLP1 APLP2	1.33e-04	3	125	2	IPR019745
Domain	Amyloid_glyco_Cu-bd	APLP1 APLP2	1.33e-04	3	125	2	IPR011178
Domain	A4_EXTRA	APLP1 APLP2	1.33e-04	3	125	2	SM00006
Domain	CBS_dom	CNNM2 CNNM3 CNNM1	3.07e-04	20	125	3	IPR000644
Domain	CBS	CNNM2 CNNM3 CNNM1	3.07e-04	20	125	3	PF00571
Domain	CBS	CNNM2 CNNM3 CNNM1	3.07e-04	20	125	3	PS51371
Domain	Growth_fac_rcpt_	EPHB2 HTRA3 FBXL19 LRP1B MEGF6 LRP1	6.39e-04	156	125	6	IPR009030
Domain	MHC_I_a_C	HLA-A HLA-H	6.55e-04	6	125	2	IPR010579
Domain	MHC_I_C	HLA-A HLA-H	6.55e-04	6	125	2	PF06623
Domain	EGF	VASN LRP1B MEGF6 BTC LRP1	1.59e-03	126	125	5	PF00008
Domain	IGv	BTN2A1 CD8A BTN2A3P BTNL9	1.61e-03	75	125	4	SM00406
Domain	Kazal_2	CPAMD8 SPOCK2 HTRA3	1.78e-03	36	125	3	PF07648
Domain	EGF_2	EPHB2 VASN ADAM12 LRP1B MEGF6 BTC LRP1	2.06e-03	265	125	7	PS01186
Domain	Leu-rich_rpt	ISLR2 LRRC38 VASN PIDD1 TSHR TPBGL FBXL19	2.33e-03	271	125	7	IPR001611
Domain	LDLR_class-A_CS	LRP1B LRP10 LRP1	2.41e-03	40	125	3	IPR023415
Domain	Cys-rich_flank_reg_C	ISLR2 LRRC38 VASN TPBGL	3.14e-03	90	125	4	IPR000483
Domain	LRRCT	ISLR2 LRRC38 VASN TPBGL	3.14e-03	90	125	4	SM00082
Domain	Ldl_recept_a	LRP1B LRP10 LRP1	3.38e-03	45	125	3	PF00057
Domain	LRR_1	ISLR2 LRRC38 VASN PIDD1 TSHR FBXL19	3.58e-03	219	125	6	PF00560
Domain	KAZAL	CPAMD8 SPOCK2 HTRA3	3.60e-03	46	125	3	SM00280
Domain	-	LRP1B LRP10 LRP1	3.60e-03	46	125	3	4.10.400.10
Domain	Ldl_recept_b	LRP1B LRP1	3.84e-03	14	125	2	PF00058
Domain	LDLRB	LRP1B LRP1	3.84e-03	14	125	2	PS51120
Domain	PRY	BTN2A1 BTN2A3P BTNL9	4.06e-03	48	125	3	SM00589
Domain	LDLRA_1	LRP1B LRP10 LRP1	4.06e-03	48	125	3	PS01209
Domain	PRY	BTN2A1 BTN2A3P BTNL9	4.06e-03	48	125	3	IPR006574
Domain	LDrepeatLR_classA_rpt	LRP1B LRP10 LRP1	4.31e-03	49	125	3	IPR002172
Domain	LDLa	LRP1B LRP10 LRP1	4.31e-03	49	125	3	SM00192
Domain	LDLRA_2	LRP1B LRP10 LRP1	4.31e-03	49	125	3	PS50068
Domain	LY	LRP1B LRP1	4.41e-03	15	125	2	SM00135
Domain	LDLR_classB_rpt	LRP1B LRP1	4.41e-03	15	125	2	IPR000033
Domain	KAZAL_2	CPAMD8 SPOCK2 HTRA3	4.56e-03	50	125	3	PS51465
Domain	Kazal_dom	CPAMD8 SPOCK2 HTRA3	4.82e-03	51	125	3	IPR002350
Domain	EMI_domain	TGFBI MEGF6	5.01e-03	16	125	2	IPR011489
Domain	EGF_3	VASN ADAM12 LRP1B MEGF6 BTC LRP1	5.04e-03	235	125	6	PS50026
Domain	EMI	TGFBI MEGF6	5.66e-03	17	125	2	PS51041
Domain	IG_LIKE	ISLR2 HLA-A HLA-H BTN2A1 TYRO3 CD8A BTN2A3P NECTIN4 BTNL9	5.79e-03	491	125	9	PS50835
Domain	-	ISLR2 LRRC38 VASN PIDD1 TSHR TPBGL FBXL19	5.89e-03	321	125	7	3.80.10.10
Domain	LRR_8	ISLR2 LRRC38 VASN PIDD1 TPBGL	5.89e-03	171	125	5	PF13855
Domain	L_dom-like	ISLR2 LRRC38 VASN PIDD1 TSHR TPBGL FBXL19	6.60e-03	328	125	7	IPR032675
Domain	EGF-like_dom	VASN ADAM12 LRP1B MEGF6 BTC LRP1	6.64e-03	249	125	6	IPR000742
Pathway	REACTOME_BUTYROPHILIN_BTN_FAMILY_INTERACTIONS	BTN2A1 BTN2A3P BTNL9	2.57e-05	9	97	3	MM15487
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	EPHB2 HLA-A VASN ESYT1 LPCAT4 APLP2 ADAM12 LRP1B BTN2A1 TGFBI CNNM3 LMF2 LRP10 VPS35 NUP210 CST3 LRP1 LRPAP1 TMEM109 CDH2 EIF2AK3 MFSD5 TANGO6	9.96e-11	1201	129	23	35696571
Pubmed	Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein lipase, alpha-2-macroglobulin and the 40,000 molecular weight receptor-associated protein.	APLP1 APLP2 LRP1 LRPAP1	6.27e-09	7	129	4	7542371
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	CPAMD8 TMEM185B CTC1 HAUS5 ETFBKMT FBXL19 MAP3K6 PCDH20 CNNM3 FANCG CDH22 PELP1 EIF4G1 PRSS50 SERPING1 MFSD5 ABTB2	1.36e-08	832	129	17	36724073
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ZXDC CTC1 ESYT1 DGKQ FBXL19 IDUA BIRC6 ARHGEF40 MEGF6 SLC45A3 CD2BP2 ENTPD2 EIF4G1 TP53I13 MMP14 DOCK6 MFSD5 TNPO3 ABTB2	2.81e-08	1105	129	19	35748872
Pubmed	Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.	CNNM2 APLP2 PCDH20 CNNM3 VPS35 CDH2	1.92e-07	67	129	6	21875946
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	IDUA CNNM3 LRP10 NUP210 ENTPD2 LRP1 MMP14 CDH2	1.93e-07	164	129	8	32409323
Pubmed	Molecular cloning and characterization of a novel gene family of four ancient conserved domain proteins (ACDP).	CNNM2 CNNM3 CNNM1	1.99e-07	4	129	3	12657465
Pubmed	Molecular cloning and characterization of the mouse Acdp gene family.	CNNM2 CNNM3 CNNM1	1.99e-07	4	129	3	14723793
Pubmed	Purification, crystallization and preliminary crystallographic analysis of the CBS pair of the human metal transporter CNNM4.	CNNM2 CNNM3 CNNM1	1.99e-07	4	129	3	21393841
Pubmed	Defining the membrane proteome of NK cells.	CAD HLA-A GHDC ESYT1 DHX38 LPCAT4 APLP2 BIRC6 CNNM3 ESYT2 LMF2 PELP1 LRP10 NUP210 GZMB EIF4G1 EIF2AK3 MFSD5	3.39e-07	1168	129	18	19946888
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	EPHB2 HLA-A GHDC ESYT1 LPCAT4 NELFB RHBDD2 ESYT2 LMF2 PELP1 VPS35 NUP210 EIF4G1 LRP1 LRPAP1 TMEM109 CDH2 TNPO3	5.20e-07	1203	129	18	29180619
Pubmed	The low density lipoprotein receptor-related protein LRP is regulated by membrane type-1 matrix metalloproteinase (MT1-MMP) proteolysis in malignant cells.	LRP1 LRPAP1 MMP14	9.89e-07	6	129	3	14645246
Pubmed	Self-class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levels.	HLA-A HLA-H CD8A	2.75e-06	8	129	3	19752186
Pubmed	Increased hepatic iron in mice lacking classical MHC class I molecules.	HLA-A HLA-H CD8A	2.75e-06	8	129	3	12393413
Pubmed	Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb.	HLA-A HLA-H CD8A	2.75e-06	8	129	3	9806638
Pubmed	Amyloid precursor-like protein 2 increases the endocytosis, instability, and turnover of the H2-K(d) MHC class I molecule.	HLA-A HLA-H APLP2	2.75e-06	8	129	3	18641335
Pubmed	Modulation of cytokine release and gene expression by the immunosuppressive domain of gp41 of HIV-1.	EPHB2 ACP5 SERPING1 MMP14 CXCL6 SLC16A10	3.25e-06	108	129	6	23383108
Pubmed	Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2.	APLP1 APLP2 LRP1	4.12e-06	9	129	3	11247302
Pubmed	CD8+ T cells accumulate in the lungs of Mycobacterium tuberculosis-infected Kb-/-Db-/- mice, but provide minimal protection.	HLA-A HLA-H CD8A	5.87e-06	10	129	3	12574368
Pubmed	An invariant T cell receptor alpha chain defines a novel TAP-independent major histocompatibility complex class Ib-restricted alpha/beta T cell subpopulation in mammals.	HLA-A HLA-H CD8A	8.05e-06	11	129	3	10377186
Pubmed	Molecular, cellular, and antigen requirements for development of age-associated T cell clonal expansions in vivo.	HLA-A HLA-H CD8A	8.05e-06	11	129	3	16365422
Pubmed	Cutting edge: antibody production to pneumococcal polysaccharides requires CD1 molecules and CD8+ T cells.	HLA-A HLA-H CD8A	1.07e-05	12	129	3	15699104
Pubmed	Striking differences of LDL receptor-related protein 1B expression in mouse and human.	LRP1B LRP1	1.37e-05	2	129	2	15963947
Pubmed	VPS35 and EIF4G1 mutations are rare in Parkinson's disease among Indians.	VPS35 EIF4G1	1.37e-05	2	129	2	23726718
Pubmed	ApoB siRNA-induced liver steatosis is resistant to clearance by the loss of fatty acid transport protein 5 (Fatp5).	APOB SLC27A5	1.37e-05	2	129	2	21826528
Pubmed	The tyrosine kinase receptor Tyro3 enhances lifespan and neuropeptide Y (Npy) neuron survival in the mouse anorexia (anx) mutation.	TYRO3 NPY	1.37e-05	2	129	2	28093506
Pubmed	D620N mutation in the VPS35 gene and R1205H mutation in the EIF4G1 gene are uncommon in the Greek population.	VPS35 EIF4G1	1.37e-05	2	129	2	26300542
Pubmed	A potential key mechanism in ascending aortic aneurysm development: Detection of a linear relationship between MMP-14/TIMP-2 ratio and active MMP-2.	TIMP2 MMP14	1.37e-05	2	129	2	30794673
Pubmed	Macrophages produce TGF-beta-induced (beta-ig-h3) following ingestion of apoptotic cells and regulate MMP14 levels and collagen turnover in fibroblasts.	TGFBI MMP14	1.37e-05	2	129	2	18354229
Pubmed	39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.	LRP1 LRPAP1	1.37e-05	2	129	2	1718973
Pubmed	Detection of a latent soluble form of membrane type 1 matrix metalloprotease bound with tissue inhibitor of matrix metalloproteinases-2 in periprosthetic tissues and fluids from loose arthroplasty endoprostheses.	TIMP2 MMP14	1.37e-05	2	129	2	24112707
Pubmed	Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor.	LRP1 LRPAP1	1.37e-05	2	129	2	3266596
Pubmed	A novel mechanism for controlling the activity of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Multiple regulatory sites for 39-kDa receptor-associated protein.	LRP1 LRPAP1	1.37e-05	2	129	2	1374383
Pubmed	The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity.	HLA-A MEX3C	1.37e-05	2	129	2	28808060
Pubmed	Structural aspects and physiological consequences of APP/APLP trans-dimerization.	APLP1 APLP2	1.37e-05	2	129	2	21952790
Pubmed	Low-density lipoprotein receptor-related protein polymorphisms in patients with elevated factor VIII coagulant activity and venous thrombosis.	LRP1 LRPAP1	1.37e-05	2	129	2	16175004
Pubmed	Affinity- and specificity-enhancing mutations are frequent in multispecific interactions between TIMP2 and MMPs.	TIMP2 MMP14	1.37e-05	2	129	2	24710006
Pubmed	The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg2+ efflux activity.	CNNM2 CNNM3	1.37e-05	2	129	2	30341174
Pubmed	Accumulation of the amyloid precursor-like protein APLP2 and reduction of APLP1 in retinoic acid-differentiated human neuroblastoma cells upon curcumin-induced neurite retraction.	APLP1 APLP2	1.37e-05	2	129	2	14597230
Pubmed	Timp-2 binding with cellular MT1-MMP stimulates invasion-promoting MEK/ERK signaling in cancer cells.	TIMP2 MMP14	1.37e-05	2	129	2	19551841
Pubmed	Polymorphism in the alpha 3 domain of HLA-A molecules affects binding to CD8.	HLA-A CD8A	1.37e-05	2	129	2	2784196
Pubmed	Differential expression of the alpha(2)-macroglobulin receptor and the receptor associated protein in normal human endometrium and endometrial carcinoma.	LRP1 LRPAP1	1.37e-05	2	129	2	11006321
Pubmed	A nucleotide deletion in exon 4 is responsible for an HLA-A null allele (A*0105N).	HLA-A HLA-H	1.37e-05	2	129	2	10519371
Pubmed	Molecular chaperone RAP interacts with LRP1 in a dynamic bivalent mode and enhances folding of ligand-binding regions of other LDLR family receptors.	LRP1 LRPAP1	1.37e-05	2	129	2	34058195
Pubmed	Frequency of the ASP620ASN mutation in VPS35 and Arg1205His mutation in EIF4G1 in familial Parkinson's disease from South Italy.	VPS35 EIF4G1	1.37e-05	2	129	2	24854799
Pubmed	Dominant thermodynamic role of the third independent receptor binding site in the receptor-associated protein RAP.	LRP1 LRPAP1	1.37e-05	2	129	2	11735425
Pubmed	Whole exome sequencing of rare variants in EIF4G1 and VPS35 in Parkinson disease.	VPS35 EIF4G1	1.37e-05	2	129	2	23408866
Pubmed	Functions of the APP gene family in the nervous system: insights from mouse models.	APLP1 APLP2	1.37e-05	2	129	2	21931985
Pubmed	Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2.	HLA-A CD8A	1.37e-05	2	129	2	9177355
Pubmed	Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor.	TIMP2 MMP14	1.37e-05	2	129	2	9724659
Pubmed	The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation.	APLP1 APLP2	1.37e-05	2	129	2	14970212
Pubmed	The amyloid beta-protein precursor and its mammalian homologues. Evidence for a zinc-modulated heparin-binding superfamily.	APLP1 APLP2	1.37e-05	2	129	2	7929392
Pubmed	TIMP-2 Interaction with MT1-MMP Activates the AKT Pathway and Protects Tumor Cells from Apoptosis.	TIMP2 MMP14	1.37e-05	2	129	2	26331622
Pubmed	ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis and increased tumor growth.	ADAM12 MMP14	1.37e-05	2	129	2	24006261
Pubmed	Tissue inhibitor of metalloproteinase-2 (TIMP-2) binds to the catalytic domain of the cell surface receptor, membrane type 1-matrix metalloproteinase 1 (MT1-MMP).	TIMP2 MMP14	1.37e-05	2	129	2	9422789
Pubmed	High Affinity Binding of the Receptor-associated Protein D1D2 Domains with the Low Density Lipoprotein Receptor-related Protein (LRP1) Involves Bivalent Complex Formation: CRITICAL ROLES OF LYSINES 60 AND 191.	LRP1 LRPAP1	1.37e-05	2	129	2	27402839
Pubmed	Amyloid-precursor Like Proteins APLP1 and APLP2 Are Dispensable for Normal Development of the Neonatal Respiratory Network.	APLP1 APLP2	1.37e-05	2	129	2	28690498
Pubmed	Nuclear translocation of the p75 neurotrophin receptor cytoplasmic domain in response to neurotrophin binding.	APLP2 NGFR	1.37e-05	2	129	2	15703394
Pubmed	Granzyme B in circulating CD8+ T cells as a biomarker of immunotherapy effectiveness and disability in neuromyelitis optica spectrum disorders.	CD8A GZMB	1.37e-05	2	129	2	36439094
Pubmed	MT1-MMP Expression Levels and Catalytic Functions Dictate LDL Receptor-Related Protein-1 Ligand Internalization Capacity in U87 Glioblastoma Cells.	LRP1 MMP14	1.37e-05	2	129	2	36430705
Pubmed	The YXXL motif, but not the two NPXY motifs, serves as the dominant endocytosis signal for low density lipoprotein receptor-related protein.	LRP1 LRPAP1	1.37e-05	2	129	2	10747918
Pubmed	CDEBP, a site-specific DNA-binding protein of the 'APP-like' family, is required during the early development of the mouse.	APLP1 APLP2	1.37e-05	2	129	2	7539437
Pubmed	Plasticity of human CD8αα binding to peptide-HLA-A*2402.	HLA-A CD8A	1.37e-05	2	129	2	21645925
Pubmed	Large-scale in silico mapping of complex quantitative traits in inbred mice.	ADAM12 CDH2	1.37e-05	2	129	2	17653278
Pubmed	Mayer-Rokitansky-Küster-Hauser syndrome discordance in monozygotic twins: matrix metalloproteinase 14, low-density lipoprotein receptor-related protein 10, extracellular matrix, and neoangiogenesis genes identified as candidate genes in a tissue-specific mosaicism.	LRP10 MMP14	1.37e-05	2	129	2	25492683
Pubmed	Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription.	APLP1 APLP2	1.37e-05	2	129	2	12228233
Pubmed	Metalloproteinases ADAM12 and MMP-14 are associated with cavernous sinus invasion in pituitary adenomas.	ADAM12 MMP14	1.37e-05	2	129	2	27144841
Pubmed	Bioorthogonal PEGylation Prolongs the Elimination Half-Life of N-TIMP2 While Retaining MMP Inhibition.	TIMP2 MMP14	1.37e-05	2	129	2	35446024
Pubmed	Allosteric modulation of ligand binding to low density lipoprotein receptor-related protein by the receptor-associated protein requires critical lysine residues within its carboxyl-terminal domain.	LRP1 LRPAP1	1.37e-05	2	129	2	12637503
Pubmed	Amyloid precursor-like protein 2 association with HLA class I molecules.	HLA-A APLP2	1.37e-05	2	129	2	19184004
Pubmed	Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism.	TIMP2 MMP14	1.37e-05	2	129	2	17991754
Pubmed	CXCR2 and RET single nucleotide polymorphisms in pancreatic cancer.	RET CXCR2	1.37e-05	2	129	2	19057948
Pubmed	Involvement of MT1-MMP and TIMP-2 in human periodontal disease.	TIMP2 MMP14	1.37e-05	2	129	2	20233321
Pubmed	VPS35 Asp620Asn and EIF4G1 Arg1205His mutations are rare in Parkinson disease from southwest China.	VPS35 EIF4G1	1.37e-05	2	129	2	23261770
Pubmed	PERK recruits E-Syt1 at ER-mitochondria contacts for mitochondrial lipid transport and respiration.	ESYT1 EIF2AK3	1.37e-05	2	129	2	36821088
Pubmed	Substrate choice of membrane-type 1 matrix metalloproteinase is dictated by tissue inhibitor of metalloproteinase-2 levels.	TIMP2 MMP14	1.37e-05	2	129	2	17425593
Pubmed	LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development.	ISLR2 RET NGFR	1.76e-05	14	129	3	19755105
Pubmed	Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.	LRP1B LRP1 LRPAP1	1.76e-05	14	129	3	15082773
Pubmed	Vitamin A-enhanced cleft palate susceptibility gene maps between C4 and B144 within the H-2 complex.	HLA-A ACP5 HLA-H	1.76e-05	14	129	3	8456115
Pubmed	CD8αα⁺ innate-type lymphocytes in the intestinal epithelium mediate mucosal immunity.	HLA-A HLA-H CD8A	2.20e-05	15	129	3	25220211
Pubmed	MHC class I family proteins retard systemic lupus erythematosus autoimmunity and B cell lymphomagenesis.	HLA-A HLA-H CD8A	2.20e-05	15	129	3	21964024
Pubmed	Control of Viral Infection by Natural Killer Cell Inhibitory Receptors.	HLA-A HLA-H GZMB	2.69e-05	16	129	3	32726632
Pubmed	Insm1 (IA-1) is a crucial component of the transcriptional network that controls differentiation of the sympatho-adrenal lineage.	RET NGFR NPY	3.26e-05	17	129	3	18094025
Pubmed	Neuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndrome.	NGFR NPY SLC16A10	3.26e-05	17	129	3	19641107
Pubmed	Variations among sublines of inbred AKR mice.	HLA-A HLA-H CD8A	3.91e-05	18	129	3	4353891
Pubmed	Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.	APLP1 APLP2	4.09e-05	3	129	2	11050115
Pubmed	Non-canonical Ret signaling augments p75-mediated cell death in developing sympathetic neurons.	RET NGFR	4.09e-05	3	129	2	30018091
Pubmed	Unraveling the potential of CD8, CD68, and VISTA as diagnostic and prognostic markers in patients with pancreatic ductal adenocarcinoma.	CD8A CD68	4.09e-05	3	129	2	38357542
Pubmed	Activated α2-macroglobulin induces Müller glial cell migration by regulating MT1-MMP activity through LRP1.	LRP1 MMP14	4.09e-05	3	129	2	23640058
Pubmed	MT-MMP, the cell surface activator of proMMP-2 (pro-gelatinase A), is expressed with its substrate in mouse tissue during embryogenesis.	TIMP2 MMP14	4.09e-05	3	129	2	8743942
Pubmed	The role of choroid plexus in IVIG-induced beta-amyloid clearance.	LRP1 LRPAP1	4.09e-05	3	129	2	24747018
Pubmed	Activation ratio of MMP-2 and expression of MT1-MMP are correlated in thymic epithelial tumours.	TIMP2 MMP14	4.09e-05	3	129	2	17886098
Pubmed	Evolutionary genomics of plant genes encoding N-terminal-TM-C2 domain proteins and the similar FAM62 genes and synaptotagmin genes of metazoans.	ESYT1 ESYT2	4.09e-05	3	129	2	17672888
Pubmed	Mechanism of Cxc Chemokine Ligand 5 (CXCL5)/Cxc Chemokine Receptor 2 (CXCR2) Bio-Axis in Mice with Acute Respiratory Distress Syndrome.	CXCL6 CXCR2	4.09e-05	3	129	2	31311916
Pubmed	[The role of matrix metalloproteinases and their tissue inhibitors in oral lichen planus].	TIMP2 MMP14	4.09e-05	3	129	2	17067460
Pubmed	The CXCL5/CXCR2 axis is sufficient to promote breast cancer colonization during bone metastasis.	CXCL6 CXCR2	4.09e-05	3	129	2	31562303
Pubmed	Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction.	ESYT1 ESYT2	4.09e-05	3	129	2	27348751
Pubmed	Gene silencing analyses against amyloid precursor protein (APP) gene family by RNA interference.	APLP1 APLP2	4.09e-05	3	129	2	16889988
Pubmed	Lengthening of G2/mitosis in cortical precursors from mice lacking beta-amyloid precursor protein.	APLP1 APLP2	4.09e-05	3	129	2	15561424
Pubmed	Granulocyte chemotactic protein-2 mediates adaptive immunity in part through IL-8Rbeta interactions.	CXCL6 CXCR2	4.09e-05	3	129	2	15356099
Interaction	CXCL3 interactions	BIRC6 TIMP2 CXCL6 CXCR2	1.26e-06	14	123	4	int:CXCL3
Interaction	RYK interactions	EPHB2 CNNM2 HLA-A APLP2 PCDH20 CNNM3 CNNM1 VPS35 CDH2	6.22e-06	212	123	9	int:RYK
Interaction	HLA-E interactions	HLA-A HLA-H CNNM1 CD8A EIF2AK3 TCTN2	8.83e-06	79	123	6	int:HLA-E
Interaction	SFTPC interactions	CNNM2 HLA-A HLA-H APLP2 IDUA NMU CNNM3 ENTPD2 EIF2AK3	9.01e-06	222	123	9	int:SFTPC
Interaction	STK32C interactions	CAD HLA-A HAUS5 RHBDD2 CNNM3 NUP210	1.54e-05	87	123	6	int:STK32C
Interaction	ASIC4 interactions	CNNM2 HLA-A CNNM3 CNNM1 ENTPD2 EIF2AK3 TCTN2	1.84e-05	134	123	7	int:ASIC4
Interaction	ASIC1 interactions	DPEP1 CNNM3 ENTPD2 EIF2AK3 TCTN2	2.54e-05	57	123	5	int:ASIC1
Interaction	SPPL3 interactions	CPAMD8 TMEM185B CTC1 HAUS5 ETFBKMT FBXL19 MAP3K6 PCDH20 CNNM3 FANCG CDH22 PELP1 EIF4G1 PRSS50 SERPING1 MFSD5 ABTB2	2.74e-05	886	123	17	int:SPPL3
Interaction	PCDHA4 interactions	APLP1 MAP3K6 NMU CNNM1 EIF2AK3	3.26e-05	60	123	5	int:PCDHA4
Interaction	TOP3B interactions	ZXDC CAD CTC1 ESYT1 DGKQ APOB FBXL19 IDUA BIRC6 ARHGEF40 MEGF6 PELP1 SLC45A3 CD2BP2 ENTPD2 EIF4G1 TP53I13 MMP14 DOCK6 MFSD5 TNPO3 ABTB2	7.50e-05	1470	123	22	int:TOP3B
Interaction	SLC22A9 interactions	APOB BIRC6 CNNM3 LMF2 MFSD5 SLC16A10	9.47e-05	120	123	6	int:SLC22A9
Interaction	TIMP1 interactions	TSHR RET TIMP2 MMP14	1.02e-04	40	123	4	int:TIMP1
Cytoband	4p16.3	TMEM175 DGKQ IDUA LRPAP1	1.04e-04	85	130	4	4p16.3
Cytoband	Ensembl 112 genes in cytogenetic band chr4p16	TMEM175 DGKQ HTRA3 IDUA LRPAP1	4.43e-04	222	130	5	chr4p16
GeneFamily	Low density lipoprotein receptors	LRP1B LRP10 LRP1	3.51e-05	13	92	3	634
GeneFamily	Butyrophilins\|V-set domain containing\|C2-set domain containing	BTN2A1 BTN2A3P BTNL9	5.55e-05	15	92	3	458
GeneFamily	Extended synaptotagmins	ESYT1 ESYT2	7.66e-05	3	92	2	827
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	EPHB2 DPAGT1 HLA-A VASN ESYT1 HLA-H APLP2 ESYT2 LMF2 LRP10 TIMP2 CST3 LRP1 LY6E TMEM109 CXCL6 EIF2AK3 MFSD5	1.14e-08	703	129	18	MM1055
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	EPHB2 DPAGT1 HLA-A VASN ESYT1 APLP2 ESYT2 LMF2 LRP10 TIMP2 CST3 LRP1 LY6E TMEM109 CXCL6 EIF2AK3 MFSD5	4.35e-08	681	129	17	M5314
Coexpression	PEREZ_TP53_TARGETS	ZXDC VASN ACP5 ASH1L PIDD1 IDUA ADAM12 CNNM3 ARHGEF40 MEGF6 LRP10 SUSD5 FGFBP3 ENTPD2 PRRT3 CST3 NECTIN4 LRPAP1 DHRS2 HSD11B2 ABTB2	4.19e-07	1201	129	21	M4391
Coexpression	MILI_PSEUDOPODIA_CHEMOTAXIS_DN	CNNM2 HLA-A VASN ESYT1 HLA-H APLP2 TIMP2 LRP1 LY6E TMEM109 MMP14 EIF2AK3	3.78e-06	470	129	12	MM1053
Coexpression	DESCARTES_FETAL_THYMUS_STROMAL_CELLS	COL5A3 HTRA3 ADAM12 SSPN LRP1 SERPING1 MMP14	5.37e-06	137	129	7	M40313
Coexpression	GSE339_CD4POS_VS_CD4CD8DN_DC_IN_CULTURE_UP	DPEP1 ACP5 APLP1 TSHR IDUA MAP3K6 BIRC6 FANCG	6.92e-06	200	129	8	M5122
Coexpression	HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	COL5A3 APLP1 ADAM12 TGFBI LRP1 MMP14 CXCL6 CDH2	6.92e-06	200	129	8	M5930
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN	ZXDC DPAGT1 GHDC CTC1 TMEM175 DGKQ SPOCK2 IDUA ZDHHC1 BTN2A1 CNNM3 MEGF6 LRP10 HPS1 CST3 TP53I13	9.95e-06	905	129	16	M40865
Coexpression	KAZMIN_PBMC_P_FALCIPARUM_RTSS_AS01_UNKN_AGE_IMM_WITH_ARR_VS_IMM_BY_RRR_PRIMARY_IMMUNIZ_WITH_RECOMB_ADENOVIRUS_35_1DY_UP	EPHB2 SERPING1 LY6E	1.36e-05	10	129	3	M41021
Coexpression	MILI_PSEUDOPODIA_CHEMOTAXIS_DN	CNNM2 HLA-A VASN ESYT1 APLP2 TIMP2 LRP1 LY6E TMEM109 MMP14 EIF2AK3	1.69e-05	457	129	11	M1613
Coexpression	ZHANG_UTERUS_C1_PROLIFERATIVE_STROMAL1_MGP_HIGH_CELL	HTRA3 TIMP2 CST3 LRP1 NGFR SERPING1 HSD11B2 TMEM109 MMP14	2.39e-05	310	129	9	MM16608
Coexpression	TABULA_MURIS_SENIS_BROWN_ADIPOSE_TISSUE_B_CELL_AGEING	HLA-A HLA-H TGFBI LRP10 TIMP2 CST3 SERPING1 CD68 TMEM109	2.45e-05	311	129	9	MM3674
Coexpression	FOROUTAN_INTEGRATED_TGFB_EMT_UP	EPHB2 TGFBI ARHGEF40 TIMP2 DHRS2 CDH2	2.92e-05	120	129	6	M42505
Coexpression	TABULA_MURIS_SENIS_MAMMARY_GLAND_BASAL_CELL_AGEING	HLA-A VASN HLA-H TIMP2 CST3 ECRG4 LRP1 SERPING1 LY6E	3.21e-05	322	129	9	MM3786
Coexpression	FOROUTAN_PRODRANK_TGFB_EMT_UP	EPHB2 ADAM12 TGFBI ARHGEF40 TIMP2 DHRS2 CDH2	3.77e-05	185	129	7	M42503
Coexpression	NABA_MATRISOME	AMH CPAMD8 TSPEAR COL5A3 SPOCK2 HTRA3 ADAM12 TGFBI MEGF6 TIMP2 BTC FGFBP3 CST3 SERPING1 MMP14 CXCL6	4.56e-05	1026	129	16	M5889
Coexpression	FOROUTAN_TGFB_EMT_UP	EPHB2 ADAM12 TGFBI ARHGEF40 TIMP2 DHRS2 CDH2	4.77e-05	192	129	7	M42501
Coexpression	DURANTE_ADULT_OLFACTORY_NEUROEPITHELIUM_FIBROBLASTS_STROMAL_CELLS	TGFBI CLDN11 SSPN TIMP2 SERPING1	5.38e-05	82	129	5	M39274
Coexpression	GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_UP	EPHB2 ESYT1 FRMPD1 SPOCK2 BTN2A1 WFDC2 CST3	5.80e-05	198	129	7	M8377
Coexpression	TABULA_MURIS_SENIS_MAMMARY_GLAND_STROMAL_CELL_AGEING	DPEP1 HLA-A HLA-H HTRA3 TIMP2 ENTPD2 CST3 LRP1 SERPING1	5.99e-05	349	129	9	MM3790
Coexpression	GSE19198_1H_VS_24H_IL21_TREATED_TCELL_UP	HLA-A ESYT1 TGFBI SSPN TIMP2 NGFR CXCR2	6.18e-05	200	129	7	M7234
Coexpression	GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_DN	ESYT1 ACP5 RHBDD2 TGFBI TIMP2 LRP1 SERPING1	6.18e-05	200	129	7	M7453
Coexpression	GSE19825_NAIVE_VS_IL2RALOW_DAY3_EFF_CD8_TCELL_UP	CASQ1 HTRA3 APLP2 TSHR ADAM12 ARHGEF40 NPY	6.18e-05	200	129	7	M4297
Coexpression	GSE9509_10MIN_VS_30MIN_LPS_STIM_IL10_KO_MACROPHAGE_UP	CNNM2 APLP2 ARHGEF40 NUP210 CST3 LRPAP1 TOP1MT	6.18e-05	200	129	7	M6904
Coexpression	DESCARTES_FETAL_KIDNEY_STROMAL_CELLS	ISLR2 COL5A3 HTRA3 ENTPD2 ECRG4 NGFR	8.73e-05	146	129	6	M40222
Coexpression	MIKKELSEN_NPC_ICP_WITH_H3K27ME3	ISLR2 HLA-A HLA-H	1.07e-04	19	129	3	MM862
Coexpression	HAY_BONE_MARROW_STROMAL	DENND2A VASN COL5A3 APOB LBP CLDN11 SSPN WFDC2 ECRG4 NGFR SERPING1 HSD11B2 MMP14	1.09e-04	767	129	13	M39209
Coexpression	ZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_OVERLAP_UP	HLA-A HLA-H CD8A GPR174 SERPING1	1.26e-04	98	129	5	MM460
Coexpression	TRAVAGLINI_LUNG_TREM2_DENDRITIC_CELL	HLA-A ACP5 APLP2 TGFBI TIMP2 CST3 LRP1 SERPING1 CD68 LRPAP1 MMP14	1.27e-04	572	129	11	M41698
Coexpression	NABA_MATRISOME	AMH TSPEAR COL5A3 SPOCK2 HTRA3 ADAM12 TGFBI MEGF6 TIMP2 BTC FGFBP3 CST3 SERPING1 MMP14 CXCL6	1.34e-04	1008	129	15	MM17056
Coexpression	ZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_RENCA_UP	HLA-A HLA-H CD8A GPR174 SERPING1	1.38e-04	100	129	5	MM458
Coexpression	MARTINEZ_TP53_TARGETS_UP	HLA-A HLA-H CASQ1 TSHR LBP TGFBI CLDN11 SLC45A3 BTC GZMB EIF4G1 TMEM109	1.68e-04	694	129	12	MM1039
Coexpression	LEIN_CHOROID_PLEXUS_MARKERS	LBP TGFBI LRP10 WFDC2 ECRG4	1.74e-04	105	129	5	M1719
Coexpression	NABA_ECM_REGULATORS	CPAMD8 HTRA3 ADAM12 TIMP2 CST3 SERPING1 MMP14	1.82e-04	238	129	7	M3468
Coexpression	DESCARTES_FETAL_MUSCLE_SATELLITE_CELLS	AMH GRIA4 CCER2 NPY	1.93e-04	58	129	4	M40256
Coexpression	LEIN_CHOROID_PLEXUS_MARKERS	LBP TGFBI LRP10 WFDC2 ECRG4	2.07e-04	109	129	5	MM1214
Coexpression	TABULA_MURIS_SENIS_HEART_AND_AORTA_FIBROBLAST_OF_CARDIAC_TISSUE_AGEING	DPEP1 HLA-A HLA-H ENTPD2 LRP1 SERPING1 LY6E MMP14	2.22e-04	327	129	8	MM3714
Coexpression	MIKKELSEN_ES_ICP_WITH_H3K4ME3	AMH GHDC ETFBKMT CASQ1 COL5A3 SSPN WFDC2 LRP1 NECTIN4 SERPING1 FITM1 TCTN2	2.60e-04	728	129	12	M2004
Coexpression	RUBENSTEIN_SKELETAL_MUSCLE_FAP_CELLS	HTRA3 SSPN TIMP2 CST3 LRP1 SERPING1	2.65e-04	179	129	6	M41745
Coexpression	FAN_OVARY_CL3_MATURE_CUMULUS_GRANULOSA_CELL_1	AMH CLDN11 VPS35 EIF4G1 CST3 LY6E CDH2	2.71e-04	254	129	7	M41705
Coexpression	CUI_DEVELOPING_HEART_C3_FIBROBLAST_LIKE_CELL	HTRA3 TGFBI TIMP2 LRP1 SERPING1	2.88e-04	117	129	5	M39300
Coexpression	HARALAMBIEVA_PBMC_M_M_R_II_AGE_11_22YO_VACCINATED_VS_UNVACCINATED_7YR_DN	CPAMD8 ESYT1 ACP5 APLP2 TPBGL ADAM12 TGFBI SSPN TIMP2 LRP1 CXCL6 SLC16A10	3.02e-04	740	129	12	M41202
Coexpression	ZHANG_UTERUS_C12_MONOCYTE	HLA-A HLA-H TGFBI CST3 CD68 LY6E	3.45e-04	188	129	6	MM16618
Coexpression	NABA_MATRISOME_ASSOCIATED	AMH CPAMD8 HTRA3 ADAM12 MEGF6 TIMP2 BTC FGFBP3 CST3 SERPING1 MMP14 CXCL6	3.45e-04	751	129	12	M5885
Coexpression	KUROKAWA_LIVER_CANCER_EARLY_RECURRENCE_DN	HLA-A VPS35	3.56e-04	6	129	2	M7182
Coexpression	TABULA_MURIS_SENIS_MAMMARY_GLAND_LUMINAL_EPITHELIAL_CELL_OF_MAMMARY_GLAND_AGEING	HLA-A VASN HLA-H APLP2 TIMP2 WFDC2 CST3 LY6E	3.64e-04	352	129	8	MM3788
Coexpression	GSE26495_PD1HIGH_VS_PD1LOW_CD8_TCELL_UP	HAUS5 LPCAT4 BTN2A1 CNNM3 MEGF6 ABTB2	3.85e-04	192	129	6	M4660
Coexpression	DURAND_STROMA_NS_UP	TMEM185B HLA-A LPCAT4 HLA-H MAP3K6 TMEM109	4.07e-04	194	129	6	MM962
Coexpression	GSE3982_EOSINOPHIL_VS_BASOPHIL_UP	ASH1L CASQ1 CNNM1 SSPN ARHGEF40 MFSD5	4.30e-04	196	129	6	M5413
Coexpression	GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN	TGFBI GZMB CST3 SCT CD68 TMEM109	4.54e-04	198	129	6	M4959
Coexpression	GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_DN	DPAGT1 AMH IDUA TIMP2 CST3 SCT	4.54e-04	198	129	6	M4443
Coexpression	GSE11057_CD4_CENT_MEM_VS_PBMC_UP	ESYT1 ASH1L LPCAT4 RHBDD2 PELP1 TP53I13	4.54e-04	198	129	6	M3116
Coexpression	FAN_EMBRYONIC_CTX_BIG_GROUPS_BRAIN_ENDOTHELIAL	DPEP1 HLA-A HLA-H ESYT2 SERPING1 LY6E TMEM109 DOCK6	4.63e-04	365	129	8	M39018
Coexpression	GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP	ESYT1 APLP2 IDUA SSPN SERPING1 TMEM109	4.66e-04	199	129	6	M7259
Coexpression	GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP	ISLR2 ACP5 TGFBI CNNM3 FGFBP3 MMP14	4.66e-04	199	129	6	M7448
Coexpression	GSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_DN	FRMPD1 DGKQ NMU CDH22 BTC NPY	4.78e-04	200	129	6	M8398
Coexpression	GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_UP	ACP5 HAUS5 BIRC6 LRP10 CST3 CD68	4.78e-04	200	129	6	M8569
Coexpression	GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_DN	EPHB2 ACP5 FRMPD1 MMP14 ABTB2 SLC16A10	4.78e-04	200	129	6	M9861
Coexpression	GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_DN	DPAGT1 DPEP1 HTRA3 APLP2 LRPAP1 BTNL9	4.78e-04	200	129	6	M6201
Coexpression	GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_DN	DPAGT1 HAUS5 IDUA FANCG VPS35 EIF2AK3	4.78e-04	200	129	6	M6313
Coexpression	HALLMARK_COMPLEMENT	SPOCK2 TIMP2 GZMB LRP1 SERPING1 MMP14	4.78e-04	200	129	6	M5921
Coexpression	GSE19825_NAIVE_VS_DAY3_EFF_CD8_TCELL_UP	RHBDD2 HTRA3 APLP2 LBP ARHGEF40 NPY	4.78e-04	200	129	6	M4305
Coexpression	TRAVAGLINI_LUNG_MACROPHAGE_CELL	ACP5 APLP2 TGFBI CST3 LRP1 SERPING1	4.91e-04	201	129	6	M41692
Coexpression	JU_AGING_TERC_TARGETS_UP	TIMP2 CXCL6	4.97e-04	7	129	2	M1875
CoexpressionAtlas	Mesoderm Day 5_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	EPHB2 DENND2A VASN RHBDD2 APLP2 RNF215 TYRO3 CLDN11 LMF2 MEGF6 LRP10 WFDC2 WTIP CST3 SCT TP53I13 LY6E TMEM109 MMP14 CDH2 TCTN2	6.04e-06	1153	129	21	PCBC_ratio_MESO-5_vs_SC_cfr-2X-p05
ToppCell	metastatic_Lymph_Node-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	HLA-A ACP5 APLP2 TGFBI TIMP2 LRP1 SERPING1 CD68 LRPAP1 LY6E MMP14 SLC16A10	7.78e-13	200	130	12	4758b96725699641b55a665533adf2d238032b09
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EPHB2 DPEP1 COL5A3 HTRA3 CLDN11 TIMP2 ENTPD2 CST3 ECRG4 LRP1 SERPING1	7.54e-12	184	130	11	01257e5c12e38b849fd3d9496c43ded666249ba5
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPEP1 COL5A3 GRIA4 HTRA3 CLDN11 TIMP2 ENTPD2 ECRG4 NGFR SERPING1 MMP14	1.13e-11	191	130	11	4b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPEP1 COL5A3 GRIA4 HTRA3 CLDN11 TIMP2 ENTPD2 ECRG4 NGFR SERPING1 MMP14	1.13e-11	191	130	11	75d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EPHB2 DPEP1 COL5A3 HTRA3 CLDN11 TIMP2 ENTPD2 CST3 ECRG4 SERPING1	1.98e-10	186	130	10	c0a036096c2cb23305605b8aaf18869d6e0fb512
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 LBP TGFBI TIMP2 ENTPD2 CST3 LRP1 SERPING1 MMP14	1.98e-10	186	130	10	ff6ccfdf2509f96caa10281c29a95b432f6c6dcc
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 VASN HTRA3 LBP TGFBI TIMP2 ENTPD2 LRP1 SERPING1 MMP14	1.98e-10	186	130	10	a7ab70b049742dfe7ee30557031bfac6412edf52
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 HTRA3 SSPN ARHGEF40 TIMP2 ENTPD2 LRP1 SERPING1 MMP14 CDH2	2.44e-10	190	130	10	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 VASN HTRA3 LBP TGFBI TIMP2 ENTPD2 LRP1 SERPING1 MMP14	2.44e-10	190	130	10	ad0f5605db6b694445ec9bd5dc8d2d834358c0f9
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A3 HTRA3 TPBGL CLDN11 ARHGEF40 TIMP2 ENTPD2 NGFR SERPING1 MMP14	2.57e-10	191	130	10	db4943dd19207663fb9e27f8940fa4b06a933625
ToppCell	facs-Aorta-Heart-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 TGFBI TIMP2 ENTPD2 LRP1 SERPING1 LRPAP1 MMP14	2.71e-10	192	130	10	2c6406bc97c3224099b94a43f2890f057b528fa6
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 LBP RET TIMP2 ENTPD2 LRP1 SERPING1 MMP14	2.71e-10	192	130	10	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	facs-Aorta-Heart-18m-Mesenchymal-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 TGFBI TIMP2 ENTPD2 LRP1 SERPING1 LRPAP1 MMP14	2.71e-10	192	130	10	47aed7c8e6f5ce1084821212a04f568319e65fd6
ToppCell	facs-Aorta-Heart-18m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 TGFBI TIMP2 ENTPD2 LRP1 SERPING1 LRPAP1 MMP14	2.71e-10	192	130	10	6d4fe7ea278efa4b9d43f8a3c282bc0e0e9abaea
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 LBP RET TIMP2 ENTPD2 LRP1 SERPING1 MMP14	2.71e-10	192	130	10	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 VASN COL5A3 HTRA3 LBP TGFBI TIMP2 ENTPD2 LRP1 MMP14	2.85e-10	193	130	10	160691b671710be10220803d788c2c961c236af1
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EPHB2 DPEP1 HTRA3 TGFBI TIMP2 ENTPD2 CST3 LRP1 SERPING1	3.44e-09	182	130	9	e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCell	facs-BAT-Fat-18m-Mesenchymal\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 DENND2A VASN COL5A3 HTRA3 TIMP2 ENTPD2 SERPING1 MMP14	4.78e-09	189	130	9	bba28f57a0708515fdd5acd9592dbbe4a4f57116
ToppCell	facs-BAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 DENND2A VASN COL5A3 HTRA3 TIMP2 ENTPD2 SERPING1 MMP14	4.78e-09	189	130	9	cf293b23a4c0e8a0c9f09115b1d53d9b11de72e2
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 ISLR2 VASN COL5A3 HTRA3 TIMP2 ENTPD2 LRP1 SERPING1	4.78e-09	189	130	9	0a8b827bba1efd885ad6c06929251c741dc3a541
ToppCell	facs-Heart-RA-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GRIA4 HTRA3 TIMP2 WFDC2 ENTPD2 CST3 ECRG4 SERPING1	4.78e-09	189	130	9	7c6d586f352d0d44c24079e76272cb3a545441b5
ToppCell	facs-BAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 DENND2A VASN COL5A3 HTRA3 TIMP2 ENTPD2 SERPING1 MMP14	4.78e-09	189	130	9	87323e86a5b5d159920a07e6bd7ef5e3438cd085
ToppCell	facs-Heart-RA-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GRIA4 HTRA3 TIMP2 WFDC2 ENTPD2 CST3 ECRG4 SERPING1	4.78e-09	189	130	9	5438baaa3056fec46d59f75f03f27a93601936c1
ToppCell	facs-SCAT-Fat-24m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 LBP TGFBI TIMP2 ENTPD2 LRP1 SERPING1 MMP14	5.01e-09	190	130	9	dc7e92f1b18d0f5efec11d09d56ba954d4f8b3bd
ToppCell	facs-SCAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 LBP TGFBI TIMP2 ENTPD2 LRP1 SERPING1 MMP14	5.01e-09	190	130	9	0bb06df3d5a50416854370f234718c6cec3d773b
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 DENND2A VASN COL5A3 HTRA3 TIMP2 LRP1 SERPING1 MMP14	5.01e-09	190	130	9	bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 DENND2A VASN COL5A3 HTRA3 TIMP2 LRP1 SERPING1 MMP14	5.01e-09	190	130	9	e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A3 HTRA3 TPBGL CLDN11 ARHGEF40 TIMP2 ENTPD2 SERPING1 MMP14	5.01e-09	190	130	9	947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCell	facs-SCAT-Fat-24m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 LBP TGFBI TIMP2 ENTPD2 LRP1 SERPING1 MMP14	5.01e-09	190	130	9	008290bb5c79446681dd6bf354336c57ad0d6f13
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 DENND2A VASN COL5A3 HTRA3 TIMP2 LRP1 SERPING1 MMP14	5.01e-09	190	130	9	ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 VASN HTRA3 LBP TIMP2 ENTPD2 CST3 LRP1 SERPING1	5.01e-09	190	130	9	d13fd234caa3fc69d8a59bc0060cdacdf716ee55
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 LBP TGFBI TIMP2 ENTPD2 LRP1 SERPING1 MMP14	5.24e-09	191	130	9	83d1915835df6f2eb23f87986d695e71398edb9d
ToppCell	facs-Aorta-Heart-18m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 TGFBI TIMP2 ENTPD2 LRP1 SERPING1 MMP14	5.24e-09	191	130	9	6242f83acaf1714e9c1771a832cb67674b19e96d
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPEP1 VASN HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1 MMP14	5.49e-09	192	130	9	fc940f91ff8e051631dbf25e6e8d73cf8337eccb
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 VASN COL5A3 LBP RET TGFBI ENTPD2 LRP1 MMP14	5.49e-09	192	130	9	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPEP1 COL5A3 HTRA3 SSPN TIMP2 ENTPD2 NGFR SERPING1 MMP14	5.49e-09	192	130	9	19b94f254d51b9bda3d9b7c6f85e27ecb58409c8
ToppCell	facs-Trachea-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPEP1 VASN HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1 MMP14	5.49e-09	192	130	9	e8af6ad1ae99cae13a82d0d8d7f38af9b777f0ba
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHB2 DPEP1 HTRA3 SSPN TIMP2 ENTPD2 NGFR SERPING1 MMP14	5.49e-09	192	130	9	ad48c941a3ddfd9a5146bafc2209da577bb50531
ToppCell	facs-BAT-Fat-24m-Mesenchymal-mesenchymal_progenitor\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1 MMP14	5.49e-09	192	130	9	0b3161ce3add9f7457f4cfa5749dbb6501e3ad36
ToppCell	facs-BAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1 MMP14	5.49e-09	192	130	9	61c7ec6171c519b2f3e9ce623669162c0c6ba9f5
ToppCell	facs-BAT-Fat-24m-Mesenchymal\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1 MMP14	5.49e-09	192	130	9	24d682e3247a73d349e7776b9e564b6b57f4cb13
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPEP1 VASN HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1 MMP14	5.49e-09	192	130	9	7a2e79490e4f7058bb76b46c45b5df9f729e3146
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 VASN COL5A3 HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1	5.74e-09	193	130	9	428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 ARHGEF40 TIMP2 ENTPD2 LRP1 SERPING1 MMP14	6.01e-09	194	130	9	ce32e60bcea1b8baf496ce9050832bc8c77d8434
ToppCell	facs-Heart-RA-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 DENND2A HTRA3 ARHGEF40 TIMP2 ENTPD2 LRP1 SERPING1 MMP14	6.01e-09	194	130	9	bc945450b350f597c3ff910d3a14a533d90086a8
ToppCell	droplet-Fat-SCAT-30m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 ISLR2 VASN HTRA3 LBP PCDH20 TIMP2 ENTPD2 SERPING1	6.01e-09	194	130	9	c2990d6eda3954dc01913bf3910df79f06e0010a
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 ARHGEF40 TIMP2 ENTPD2 LRP1 SERPING1 MMP14	6.01e-09	194	130	9	a1dc157148885cc8d3685ac81a1f4e3562aeecc9
ToppCell	droplet-Fat-SCAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 ISLR2 VASN HTRA3 LBP PCDH20 TIMP2 ENTPD2 SERPING1	6.01e-09	194	130	9	0e315c63407fa00643722a7d6138b1502f79b10d
ToppCell	droplet-Fat-SCAT-30m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 ISLR2 VASN HTRA3 LBP PCDH20 TIMP2 ENTPD2 SERPING1	6.01e-09	194	130	9	588c45dafa00547b2506e298a2434b1b5e15560d
ToppCell	Monocytes-M2-like_CD16+_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	EPHB2 TGFBI ARHGEF40 TIMP2 CST3 LRP1 SERPING1 CD68 MMP14	6.28e-09	195	130	9	10fa47bdcf6c9784ea930b75a5861e139421feed
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 DENND2A HTRA3 ARHGEF40 TIMP2 ENTPD2 LRP1 SERPING1 MMP14	6.28e-09	195	130	9	690d6e15d7c863fc8f2d33b1f7bf86f019f415c9
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 DENND2A HTRA3 ARHGEF40 TIMP2 ENTPD2 LRP1 SERPING1 MMP14	6.28e-09	195	130	9	5c05e2bcea3d5d7ebe6325f7187ccf83301053d8
ToppCell	facs-SCAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 VASN COL5A3 HTRA3 TIMP2 ENTPD2 LRP1 SERPING1 MMP14	6.57e-09	196	130	9	65f2f51e17f1869f3468813127b96d3048d8ad41
ToppCell	facs-SCAT-Fat-18m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 VASN COL5A3 HTRA3 TIMP2 ENTPD2 LRP1 SERPING1 MMP14	6.57e-09	196	130	9	2cd83176f2e8a9e6fa3c08cb33928a61e5fc43b6
ToppCell	facs-SCAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 VASN COL5A3 HTRA3 TIMP2 ENTPD2 LRP1 SERPING1 MMP14	6.57e-09	196	130	9	e4ed897900a6472738bc6be2fb4817192727225d
ToppCell	COVID-19_Moderate-Classical_Monocyte\|World / disease group, cell group and cell class	EPHB2 APLP2 TGFBI ARHGEF40 TIMP2 CST3 LRP1 SERPING1 CD68	6.87e-09	197	130	9	16cf3939e700aef1e16159f0652ba2dfad287e7a
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HLA-A ACP5 RHBDD2 TGFBI CST3 SERPING1 CD68 LRPAP1 LY6E	6.87e-09	197	130	9	d0c6b2d22470ff1134b676ed9296fa7a55d915e7
ToppCell	LAM-Myeloid-Macrophage\|Myeloid / Condition, Lineage and Cell class	ACP5 RHBDD2 APLP2 TIMP2 LRP1 SERPING1 CD68 LRPAP1 LY6E	6.87e-09	197	130	9	355fe286609df2ded973952f1856bbc5f437cfd0
ToppCell	Mesenchymal_cells-Arteriolar_fibro.\|Mesenchymal_cells / Lineage and Cell class	ACP5 HTRA3 TGFBI TIMP2 ENTPD2 CST3 LRP1 SERPING1 LY6E	6.87e-09	197	130	9	cb321836980e7b4efbb9284c6af7ccd34079d2be
ToppCell	BAL-Control-Myeloid-TRAM\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ACP5 APLP2 TIMP2 CST3 LRP1 SERPING1 CD68 LRPAP1 LY6E	7.50e-09	199	130	9	0bf2ce7ebae9a77add8d72ec9ec0c6a022dfd092
ToppCell	BAL-Control-Myeloid-TRAM\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ACP5 APLP2 TIMP2 CST3 LRP1 SERPING1 CD68 LRPAP1 LY6E	7.50e-09	199	130	9	a6a8d9e62d1c5948d1c5cd7643db6e482b31d165
ToppCell	Control-Myeloid-TRAM1\|Myeloid / Condition, Lineage and Cell class	ACP5 RHBDD2 APLP2 CST3 LRP1 SERPING1 CD68 LRPAP1 LY6E	7.50e-09	199	130	9	664f5cab3fe5ab599d1944deed04857ae14a06d5
ToppCell	mild_COVID-19_(asymptomatic)-Classical_Monocyte\|World / disease group, cell group and cell class (v2)	EPHB2 APLP2 TGFBI TIMP2 CST3 LRP1 SERPING1 CD68 LY6E	7.50e-09	199	130	9	727122b6f4ca265d2826c9271b10a4215a9d45a3
ToppCell	BAL-Severe-cDC_0\|Severe / Compartment, Disease Groups and Clusters	ACP5 RHBDD2 APLP2 TGFBI TIMP2 LRP1 CD68 LRPAP1 MMP14	7.50e-09	199	130	9	d39be8b173156bf87baddd3caed4b35597c53ea1
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte\|Control_saline / Treatment groups by lineage, cell group, cell type	DENND2A ISLR2 CNNM2 COL5A3 TYRO3 SUSD5 ECRG4 LRP1 CDH2	7.83e-09	200	130	9	cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte-3\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ISLR2 ATG9B LPCAT4 TYRO3 CNNM1 CLDN11 MEGF6 SCT	4.63e-08	174	130	8	76310c0af1d7df6a4de3816838b2ac2892f68746
ToppCell	facs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 LBP ENTPD2 LRP1 SERPING1 MMP14	5.06e-08	176	130	8	cccf9201f6e2da7524b911a5961d3b227edab222
ToppCell	facs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 LBP ENTPD2 LRP1 SERPING1 MMP14	5.06e-08	176	130	8	c0a084f7a8645262d61971f094689e02bf15b113
ToppCell	facs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 LBP TIMP2 ENTPD2 SERPING1 MMP14	5.06e-08	176	130	8	fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCell	facs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 LBP TIMP2 ENTPD2 SERPING1 MMP14	5.06e-08	176	130	8	f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HLA-A ACP5 RHBDD2 TGFBI LRP1 SERPING1 CD68 LRPAP1	5.52e-08	178	130	8	0b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EPHB2 DPEP1 HTRA3 TGFBI TIMP2 ENTPD2 LRP1 SERPING1	6.02e-08	180	130	8	9adebde5f4ca6dcb90e9113622862e14298465ac
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPEP1 COL5A3 HTRA3 TIMP2 ENTPD2 LRP1 SERPING1 MMP14	6.28e-08	181	130	8	3462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCell	metastatic_Brain-Fibroblasts-Myofibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	ISLR2 DRD4 HTRA3 CLDN11 SSPN ECRG4 SCT MMP14	6.28e-08	181	130	8	bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPEP1 COL5A3 HTRA3 TIMP2 ENTPD2 LRP1 SERPING1 MMP14	6.28e-08	181	130	8	6730e249cac55ae892cc567d9211615882f3dab4
ToppCell	droplet-Limb_Muscle-nan-21m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VASN HTRA3 LBP TIMP2 ENTPD2 CST3 LRP1 SERPING1	6.55e-08	182	130	8	a51cbdb8d6528a82044be838c70c492fc6370891
ToppCell	facs-Heart-LA-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1 MMP14	7.75e-08	186	130	8	ed0a91f47e77fe21d4c7678d0f2a7c5f97d63dda
ToppCell	facs-Trachea-nan-24m-Mesenchymal\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1 MMP14	8.08e-08	187	130	8	71385068e3fd0bfa7822ae176113a49460c8636b
ToppCell	facs-Heart-LA-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1 MMP14	8.08e-08	187	130	8	1669df899b1759c338ffce196fe009840123cfcd
ToppCell	facs-Trachea-nan-24m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1 MMP14	8.08e-08	187	130	8	b930d5f7d410ac1f340babec5c937388f64cafc0
ToppCell	facs-Trachea-nan-24m-Mesenchymal-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1 MMP14	8.08e-08	187	130	8	e891e571f6bb9433a0046215de6cabd89ed1effc
ToppCell	facs-Bladder-nan-24m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 LBP TIMP2 CST3 LRP1 SERPING1 MMP14	8.08e-08	187	130	8	2c145e9d11424939dd99012a8cedf5d998b966e9
ToppCell	facs-Heart-LA-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1 MMP14	8.08e-08	187	130	8	f3ef3f5a761f8306edc39bf16e76e44aae6fa7f6
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 VASN HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1	8.42e-08	188	130	8	2cfa41c64eccb28b5e22f0f91bbc921b75713245
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 VASN HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1	8.77e-08	189	130	8	56f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HTRA3 TGFBI TIMP2 CST3 LRP1 NGFR SERPING1 LY6E	9.13e-08	190	130	8	7f6dafd5418764d67f6d5ec2153233b791910e81
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HLA-A VASN APLP1 SPOCK2 APLP2 TYRO3 TIMP2 CST3	9.13e-08	190	130	8	92710caaff05123cf8e909319d7ac441d9b31a66
ToppCell	droplet-Mammary_Gland-nan-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 COL5A3 HTRA3 TIMP2 ENTPD2 CST3 LRP1 SERPING1	9.51e-08	191	130	8	8022059e434fd411dc539819f969bd4f94861281
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 TIMP2 ENTPD2 LRP1 NGFR SERPING1 MMP14	9.51e-08	191	130	8	6cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 TIMP2 ENTPD2 LRP1 NGFR SERPING1 MMP14	9.51e-08	191	130	8	850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 TIMP2 ENTPD2 LRP1 NGFR SERPING1 MMP14	9.51e-08	191	130	8	8b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VASN LBP SSPN TIMP2 LRP1 NGFR SERPING1 MMP14	9.51e-08	191	130	8	4e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VASN COL5A3 HTRA3 TIMP2 ENTPD2 ECRG4 LRP1 SERPING1	9.51e-08	191	130	8	1b26056df078674f37a6c06f6256b30cfcec21a7
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPEP1 COL5A3 HTRA3 TIMP2 ENTPD2 LRP1 SERPING1 MMP14	9.90e-08	192	130	8	321850b0f881420c2d57d3e825e365c82fa511ab
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 TGFBI TIMP2 ENTPD2 CST3 LRP1 SERPING1 MMP14	9.90e-08	192	130	8	11088878043a6ff95ba1970361256a82e434b80a
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPEP1 COL5A3 HTRA3 TIMP2 ENTPD2 LRP1 SERPING1 MMP14	9.90e-08	192	130	8	cf2765d8bc074f7f9ee864eae632a3b705175842
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1 MMP14	9.90e-08	192	130	8	136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 HTRA3 LBP TIMP2 ENTPD2 LRP1 SERPING1 MMP14	9.90e-08	192	130	8	5e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPEP1 COL5A3 HTRA3 TIMP2 ENTPD2 LRP1 SERPING1 MMP14	9.90e-08	192	130	8	29bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPEP1 COL5A3 HTRA3 TIMP2 ENTPD2 LRP1 SERPING1 MMP14	9.90e-08	192	130	8	cdc652dbfabe41b324fd85c1ed933d29fb73a49f
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HLA-A APLP2 WFDC2 CST3 LY6E	4.15e-05	50	84	5	GAVISH_3CA_METAPROGRAM_EPITHELIAL_EPI4
Computational	Enzyme inhibitors (esp serine proteases).	APLP2 TIMP2 WFDC2 CST3 SERPING1	1.09e-04	61	84	5	MODULE_164
Drug	iodide	DRD4 HLA-A APOB TSHR RET BIRC6 TGFBI CD8A LRP1 NGFR SCT CD68 LRPAP1 SLC4A9 NPY CXCR2	6.23e-08	534	129	16	CID000024841
Drug	Chloropyramine hydrochloride [6170-42-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A	ASAP3 PIDD1 DGKQ SPOCK2 IDUA NMU MEGF6 WFDC2 HPS1 MMP14	1.98e-07	198	129	10	4414_DN
Drug	Calycanthine [595-05-1]; Up 200; 11.6uM; PC3; HT_HG-U133A	DENND2A AMH CNNM2 ASAP3 SPOCK2 IDUA ADAM12 TGFBI LRP1 SLC16A10	2.17e-07	200	129	10	5744_UP
Drug	GW8510; Up 200; 10uM; PC3; HT_HG-U133A	EPHB2 DENND2A CTC1 APLP1 TGFBI HPS1 LRP1 MMP14 TCTN2	1.18e-06	186	129	9	7067_UP
Drug	Metolazone [17560-51-9]; Up 200; 11uM; PC3; HG-U133A	EPHB2 DENND2A LPCAT4 APLP1 LMF2 HPS1 CST3 LY6E CDH2	2.06e-06	199	129	9	1932_UP
Drug	Diethylcarbamazine citrate [1642-54-2]; Down 200; 10.2uM; PC3; HT_HG-U133A	EPHB2 ZXDC DENND2A CNNM2 PIDD1 ADAM12 HPS1 DHRS2	1.70e-05	197	129	8	5066_DN
Drug	Dienestrol [84-17-3]; Down 200; 15uM; PC3; HT_HG-U133A	EPHB2 DENND2A PIDD1 ADAM12 LMF2 NUP210 MMP14 DOCK6	1.76e-05	198	129	8	5727_DN
Drug	AC1NRD2Z	HLA-A BIRC6 TYRO3 GZMB	1.81e-05	28	129	4	CID005289327
Disease	Colorectal Carcinoma	DPAGT1 DPEP1 CPAMD8 CAD ASAP3 TSPEAR APOB RET FANCG CDH22 EIF4G1 LRP1 DHRS2 RIC3	1.94e-06	702	126	14	C0009402
Disease	systemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus	DRD4 DGKQ SCT TNPO3	2.09e-05	38	126	4	EFO_0000685, EFO_0000717, EFO_0000783, MONDO_0007915
Disease	alpha-L-iduronidase measurement	TMEM175 DGKQ IDUA	4.95e-05	17	126	3	EFO_0020139
Disease	Marfan syndrome (is_marker_for)	TIMP2 MMP14	1.08e-04	4	126	2	DOID:14323 (is_marker_for)
Disease	Septicemia	LBP TGFBI CXCR2	1.44e-04	24	126	3	C0036690
Disease	Sepsis	LBP TGFBI CXCR2	1.44e-04	24	126	3	C0243026
Disease	Severe Sepsis	LBP TGFBI CXCR2	1.44e-04	24	126	3	C1719672
Disease	Pyemia	LBP TGFBI CXCR2	1.44e-04	24	126	3	C0034189
Disease	Moyamoya disease (is_implicated_in)	HLA-A TIMP2	1.79e-04	5	126	2	DOID:13099 (is_implicated_in)
Disease	level of Sphingomyelin (d42:2) in blood serum	PELP1 BTC CXCL6	2.56e-04	29	126	3	OBA_2045183
Disease	level of Sphingomyelin (d38:1) in blood serum	PELP1 BTC CXCL6	2.84e-04	30	126	3	OBA_2045180
Disease	free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	DGKQ APOB BIRC6 CDH22 WFDC2 DOCK6 TANGO6	3.35e-04	303	126	7	EFO_0004612, EFO_0020945
Disease	level of Sphingomyelin (d40:1) in blood serum	PELP1 BTC CXCL6	3.44e-04	32	126	3	OBA_2045182
Disease	Alzheimer's disease 1 (implicated_via_orthology)	APLP1 APLP2	3.75e-04	7	126	2	DOID:0080348 (implicated_via_orthology)
Disease	brain infarction (biomarker_via_orthology)	CD8A GZMB MMP14	3.78e-04	33	126	3	DOID:3454 (biomarker_via_orthology)
Disease	Cardiovascular Diseases	APOB CST3 NPY	4.90e-04	36	126	3	C0007222
Disease	systemic scleroderma	ESYT1 TMEM175 DGKQ TNPO3	4.91e-04	85	126	4	EFO_0000717
Disease	influenza A (H1N1)	APLP1 ADAM12 LRP1B ESYT2	5.37e-04	87	126	4	EFO_1001488
Disease	lipid measurement, high density lipoprotein cholesterol measurement	ASAP3 DGKQ APOB CDH22 WFDC2 DOCK6 TANGO6	5.57e-04	330	126	7	EFO_0004529, EFO_0004612
Disease	deoxycholate measurement	CPAMD8 MEX3C NMU	6.21e-04	39	126	3	EFO_0010475
Disease	basophil count	HLA-A HLA-H RHBDD2 LBP SLC45A3 BTN2A3P TNFRSF13C CXCR2	1.13e-03	483	126	8	EFO_0005090
Disease	total lipids in lipoprotein particles measurement	DHX38 APOB DOCK6	1.14e-03	48	126	3	EFO_0022309
Disease	congestive heart failure (biomarker_via_orthology)	TIMP2 NGFR MMP14 NPY	1.17e-03	107	126	4	DOID:6000 (biomarker_via_orthology)
Disease	Early Pregnancy Loss	TGFBI CD8A TIMP2 CD68	1.25e-03	109	126	4	C3830362
Disease	Spontaneous abortion	TGFBI CD8A TIMP2 CD68	1.25e-03	109	126	4	C0000786
Disease	Miscarriage	TGFBI CD8A TIMP2 CD68	1.25e-03	109	126	4	C4552766
Disease	Abortion, Tubal	TGFBI CD8A TIMP2 CD68	1.25e-03	109	126	4	C0000822
Disease	intracranial aneurysm (biomarker_via_orthology)	TIMP2 CST3	1.37e-03	13	126	2	DOID:10941 (biomarker_via_orthology)
Disease	gallbladder cancer (is_implicated_in)	APOB LRP1B	1.37e-03	13	126	2	DOID:3121 (is_implicated_in)
Disease	thoracic aortic aneurysm (is_marker_for)	TIMP2 MMP14	1.59e-03	14	126	2	DOID:14004 (is_marker_for)
Disease	intracranial aneurysm (is_marker_for)	CST3 MMP14	1.59e-03	14	126	2	DOID:10941 (is_marker_for)
Disease	lysophosphatidylcholine 15:0 measurement	LRP1B CXCL6	1.59e-03	14	126	2	EFO_0020941
Disease	Arthritis, Psoriatic	FBXL19 CD68	1.59e-03	14	126	2	C0003872
Disease	Myopia	GRIA4 LRPAP1	1.83e-03	15	126	2	C0027092
Disease	Alzheimer's disease (implicated_via_orthology)	APLP1 APLP2 LRP1	1.88e-03	57	126	3	DOID:10652 (implicated_via_orthology)
Disease	Alzheimer's disease (biomarker_via_orthology)	LRP1 NGFR NPY	1.98e-03	58	126	3	DOID:10652 (biomarker_via_orthology)
Disease	Seasonal Affective Disorder	DRD4 NPY	2.09e-03	16	126	2	C0085159
Disease	level of Sterol ester (27:1/18:1) in blood serum	BTC CXCL6	2.09e-03	16	126	2	OBA_2045195
Disease	phospholipids:total lipids ratio, high density lipoprotein cholesterol measurement	HLA-A DHX38 DGKQ APOB WFDC2 DOCK6	2.10e-03	307	126	6	EFO_0004612, EFO_0020946
Disease	telomere length	GHDC CTC1 TSPEAR FBXL19 SSPN TNPO3	2.31e-03	313	126	6	EFO_0004505
Disease	depressive disorder (is_implicated_in)	NGFR NPY	2.36e-03	17	126	2	DOID:1596 (is_implicated_in)
Disease	response to radiation, Urinary retention	LRP1B LRPAP1	2.36e-03	17	126	2	GO_0009314, HP_0000016
Disease	free cholesterol measurement, high density lipoprotein cholesterol measurement	ASAP3 DGKQ APOB CDH22 WFDC2 DOCK6	2.38e-03	315	126	6	EFO_0004612, EFO_0008591
Disease	total cholesterol measurement, high density lipoprotein cholesterol measurement	DGKQ APOB CDH22 WFDC2 DOCK6 TANGO6	2.38e-03	315	126	6	EFO_0004574, EFO_0004612
Disease	phospholipid measurement, high density lipoprotein cholesterol measurement	HLA-A ASAP3 DGKQ APOB CDH22 DOCK6	2.62e-03	321	126	6	EFO_0004612, EFO_0004639
Disease	periodontitis	LBP LRP1B TIMP2 CDH2 NPY	2.75e-03	223	126	5	EFO_0000649
Disease	limited scleroderma	DGKQ TNPO3	2.95e-03	19	126	2	EFO_1001017
Disease	dense area measurement, mammographic density measurement	SSPN BTC	2.95e-03	19	126	2	EFO_0005941, EFO_0006503
Disease	Grand Mal Status Epilepticus	RET CDH2 EIF2AK3	2.98e-03	67	126	3	C0311335
Disease	Status Epilepticus, Subclinical	RET CDH2 EIF2AK3	2.98e-03	67	126	3	C0751522
Disease	Simple Partial Status Epilepticus	RET CDH2 EIF2AK3	2.98e-03	67	126	3	C0751524
Disease	Non-Convulsive Status Epilepticus	RET CDH2 EIF2AK3	2.98e-03	67	126	3	C0751523
Disease	Petit mal status	RET CDH2 EIF2AK3	2.98e-03	67	126	3	C0270823
Disease	Complex Partial Status Epilepticus	RET CDH2 EIF2AK3	2.98e-03	67	126	3	C0393734
Disease	Status Epilepticus	RET CDH2 EIF2AK3	3.11e-03	68	126	3	C0038220
Disease	type 1 diabetes mellitus (is_marker_for)	APOB TIMP2 HSD11B2	3.66e-03	72	126	3	DOID:9744 (is_marker_for)
Disease	obesity (biomarker_via_orthology)	DRD4 CST3 HSD11B2 NPY	3.70e-03	147	126	4	DOID:9970 (biomarker_via_orthology)
Disease	low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	ASAP3 APOB DOCK6 TANGO6	4.26e-03	153	126	4	EFO_0004611, EFO_0020946

Protein segments in the cluster

Peptide	Gene	Start	Entry
ELLPLLLDRATDLIL	PTRH1	186	Q86Y79
RPASLLLLLSLCALV	BTN2A3P	11	Q96KV6
RLLALALALALGPAA	TGFBI	6	Q15582
ALTLGALTLPLARLL	ESYT1	551	Q9BSJ8
GLLAQLARSFALLLP	ESYT2	111	A0FGR8
LPSLQKLRSLLAEGL	SLC4A9	126	Q96Q91
ATLPLLLVLAALALG	BTNL9	261	Q6UXG8
LLGSRDPDLKDRALL	ASH1L	196	Q9NR48
LTLDLLGPSELLLAL	ASAP3	481	Q8TDY4
PDLQTLGLSVLLDLR	ARHGEF40	581	Q8TER5
ARPAVLALTGLALLL	ECRG4	6	Q9H1Z8
LLDSGLPSLLVRSLA	BIRC6	3626	Q9NR09
LPREQLLLLGTLTDL	CTC1	106	Q2NKJ3
LLLLLLGLAARTVAA	EIF2AK3	16	Q9NZJ5
LLLAFLLLPRADAGE	GZMB	6	P10144
LLLLLLRAQPAIGSL	APLP1	26	P51693
GRLLTALVLPDLLHA	DGKQ	566	P52824
ARALLLALAGALLAP	ADAM12	11	O43184
TALLLPLALLLHAAR	CD8A	6	P01732
VRSFLRGLPALLLLL	LRPAP1	6	P30533
SDLRLGRPLLAALAL	HSD11B2	26	P80365
GRPLLAALALLAALD	HSD11B2	31	P80365
ALELTKGLLPLLRSS	HSD11B2	196	P80365
GSLCALLALLLLLTP	CXCL6	16	P80162
LGSAPLPALRLLDLR	FBXL19	526	Q6PCT2
RFLALANGSLLVPLL	ISLR2	331	Q6UXK2
LLLPLLTLGTALASL	MMP14	11	P50281
LLLAALARLLGPSEV	TP53I13	11	Q8NBR0
PRTLLLLLSGALALT	HLA-H	6	P01893
ATGRLLLLLLVGLTA	APLP2	11	Q06481
LLLLLVGLTAPALAL	APLP2	16	Q06481
SDRSILLPLIIGLIL	CD68	316	P34810
RGLLLLTLSVLLAAG	NUP210	6	Q8TEM1
LIGSLAEDLRLLPRS	PCDH20	81	Q8N6Y1
LRASLSPSLLLLLSG	FGFBP3	6	Q8TAT2
GLLALQSELLRITLP	LBP	46	P18428
LLLLLLGGALAHPDR	LRP10	6	Q7Z4F1
LALLTLSGLLPIARV	LRP1B	6	Q9NZR2
LLGALLAPIRVLLAF	LPCAT4	41	Q643R3
VAAASPLLLLLLLLA	NMU	16	P48645
LLLLLPLLSALVAAA	LRP1	6	Q07954
RSLLPPLLLAAAGLA	ENTPD2	6	Q9Y5L3
ALLTPLVGRLARLLE	MAP3K6	211	O95382
LGAALLLLPLLAAVE	EPHB2	6	P29323
LGPIHERNLTLLLLL	DPAGT1	371	Q9H3H5
VLQLRPSLRGALLSL	GRIA4	131	P48058
GLSLLLALPVLLFRR	CXCR2	171	P25025
LLDALRSPGLRALEA	GHDC	186	Q8N2G8
PDLLLLLRLLALGQG	NELFB	336	Q8WX92
RPLVLALLLVSAALS	KCT2	31	Q8NC54
LERLLDGEEPLLLLL	AMH	336	P03971
ALAALPALRSLRLDG	LRRC38	171	Q5VT99
LLPELLSALHRLVGL	FANCG	131	O15287
LASGLVLALSLLLPK	RIC3	11	Q7Z5B4
LAIADLLQVLSLPLR	GPR174	61	Q9BXC1
LLPAAASLRQDLLLL	HAUS5	511	O94927
PRLRLLLLESVSGLL	PELP1	31	Q8IZL8
LAAADLLLALLVLPL	DRD4	76	P21917
ALLEGLLELLLPRET	CD2BP2	156	O95400
LLALPALLLLLLAGA	APOB	11	P04114
LLLAALAALALAREP	HTRA3	6	P83110
LTLPQLGRLLDLLYL	DOCK6	1276	Q96HP0
FLIGLLSSSLPLLRE	DENND2A	816	Q9ULE3
PASELLLLRLLLLGA	CCER2	6	I3L3R5
LLLRLLLLGAATAAP	CCER2	11	I3L3R5
APLRLVFLLNVLLLG	FITM1	216	A5D6W6
LLETKALGLLAPLRE	FRMPD1	896	Q5SYB0
AVPGLRLALLLLLVL	CASQ1	11	P31415
PLLLLLLSARDGVRA	CPAMD8	11	Q8IZJ3
IAASVLGLPAILLLL	CLDN11	86	O75508
RSSPLLVLLLVLAAG	ATG9B	276	Q674R7
RPASLLLLLLSLCAL	BTN2A1	11	Q7KYR7
TLLTLLLLLLAGDRA	SERPING1	6	P05155
PRAALLALLASLLAA	IDUA	6	P35475
LRPLGKAASLLLEIL	EIF4G1	1366	Q04637
PRTLLLLLSGALALT	HLA-A	6	P04439
AGLLLSLLPALLRFG	LY6E	116	Q16553
RAGVALSPALLLLLL	CDH22	11	Q9UJ99
LLLQALRSSGLLLFP	ETFBKMT	16	Q8IXQ9
ASSLRPADLLALILL	HPS1	226	Q92902
SSLPLLLALALGLVI	BTC	11	P35070
ALLGLTRTLALELAP	DHRS2	191	Q13268
LLLASLAPLVLCLSL	DPEP1	396	P16444
LLLLLLLLGGSAARP	SCT	6	P09683
PLLLTALAALTLLGL	PRRT3	546	Q5FWE3
GALRTLLPLLAALLQ	CDH2	6	P19022
RAPLLLLAILAVALA	CST3	6	P01034
RAGLCLLLAALQLLP	COL5A3	11	P25940
AAIPLLALAGALALR	MFSD5	206	Q6N075
LLASVPADLARLPLL	PIDD1	251	Q9HB75
GRAVVLALVLLLLPA	MEGF6	11	O75095
AAALLLLGLPRLSVR	SUSD5	21	O60279
LLLFSVLLPLRLDGI	TMEM185B	21	Q9H7F4
ALVALGALLLSPLRH	LMF2	86	Q9BU23
LLLRERLAALGLDDP	MEX3C	46	Q5U5Q3
RALFLGASALLLLIL	RNF215	146	Q9Y6U7
AALGASLAAARLLPL	SELENOO	6	Q9BVL4
RFPLLLALLQLALGI	SSPN	51	Q14714
ALSLGILLSLFLIPR	SLC45A3	91	Q96JT2
ELVSLLLSRGADPLL	ABTB2	621	Q8N961
GLRLSLLSLDPVELR	CNNM1	241	Q9NRU3
LQAAAGRLLPLLLLS	CNNM2	41	Q9H8M5
LAPRALGLSRLAVLL	CNNM3	251	Q8NE01
LGLSRLAVLLTLPVA	CNNM3	256	Q8NE01
LGPLAAALLLSLLLF	WFDC2	6	Q14508
GILLRSAELALLLHP	UHRF1BP1L	861	A0JNW5
LLVRLDRGVLALSAP	ZXDC	136	Q2QGD7
PCAFLLLRLLVGLAL	TMEM175	456	Q9BSA9
LAAAALALTLLPARL	SLC27A5	66	Q9Y2P5
DGPRLLLLLLLGVSL	NGFR	11	P08138
LAELPLRLFLQGALA	VPS35	576	Q96QK1
LLSLLVSGPRLFLLQ	RHBDD2	26	Q6NTF9
RLGLSGLTLALSLLV	NPY	6	P01303
ALGLLLLATLLRPAD	TIMP2	11	P16035
LLRLRAALTLLGEVP	TOP1MT	6	Q969P6
GLDRILEALKLLLSP	TANGO6	16	Q9C0B7
ALLILQALLLPSLAD	ACP5	6	P13686
PSLLGLDLLASLKRR	DHX38	46	Q92620
LPLLLTAVSEGRLSL	CAD	1711	P27708
LLIAPALAAVLLAAL	VASN	576	Q6EMK4
SGAAGLRLLLLLLLP	RET	6	P07949
DPSTRALLLLALLIL	TMEM109	181	Q9BVC6
LLKGTALVLARLPLD	TNPO3	561	Q9Y5L0
LAALDAALAPLAELR	TPBGL	161	P0DKB5
AALAPLAELRLLGLA	TPBGL	166	P0DKB5
AALLLAGLALRELEP	WTIP	11	A6NIX2
AEESDLLLLGLRLSP	TSPEAR	111	Q8WU66
LLLLGLRLSPAQLHF	TSPEAR	116	Q8WU66
ALRLLEALLQTGPHL	XKR5	111	Q6UX68
TSAPSRAGALLLLLL	PRSS50	16	Q9UI38
RAGALLLLLLLLRSA	PRSS50	21	Q9UI38
ALALPAPSRTLLLAL	PRSS50	361	Q9UI38
APALLGLALVLALVL	TNFRSF13C	81	Q96RJ3
PAALLLRLFLLQGIL	TCTN2	6	Q96GX1
GALLLAPLLLLQLAT	THSD8	6	A0A1W2PP97
PRLGLLLAALASLLL	TYRO3	21	Q06418
LPLLLLAAAALAEGD	SPOCK2	11	Q92563
PAILALAALLILLGL	ZDHHC1	241	Q8WTX9
LLQLVLLLDLPRDLG	TSHR	6	P16473
LLPLLLRVLIDSVGL	SLC16A10	216	Q8TF71
LLLLLLLASFTGRCP	NECTIN4	16	Q96NY8