Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	cilium organization	CFAP100 KIFAP3 RPGRIP1L CCDC42 SYNE1 CEP250 CNTRL TBC1D2 CEP126 CFAP53 HTT	2.82e-06	476	82	11	GO:0044782
GeneOntologyBiologicalProcess	cilium assembly	CFAP100 RPGRIP1L CCDC42 SYNE1 CEP250 CNTRL TBC1D2 CEP126 CFAP53 HTT	1.04e-05	444	82	10	GO:0060271
GeneOntologyBiologicalProcess	microtubule-based process	CFAP100 KIFAP3 HOOK1 CCDC42 INSC CEP250 CNTRL MACF1 CHEK1 CEP126 CLIP1 CFAP53 OPA1 MADD HTT	1.59e-05	1058	82	15	GO:0007017
GeneOntologyBiologicalProcess	positive regulation of ion transmembrane transporter activity	TCAF1 CRACR2A ACTN4 DMD HTT	4.25e-05	97	82	5	GO:0032414
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection assembly	CFAP100 RPGRIP1L CCDC42 SYNE1 CEP250 CNTRL ZMYND8 TBC1D2 CEP126 CFAP53 HTT	6.74e-05	670	82	11	GO:0120031
GeneOntologyBiologicalProcess	positive regulation of transporter activity	TCAF1 CRACR2A ACTN4 DMD HTT	6.79e-05	107	82	5	GO:0032411
GeneOntologyBiologicalProcess	cell projection assembly	CFAP100 RPGRIP1L CCDC42 SYNE1 CEP250 CNTRL ZMYND8 TBC1D2 CEP126 CFAP53 HTT	8.21e-05	685	82	11	GO:0030031
GeneOntologyBiologicalProcess	organelle localization	KIFAP3 CENPF INSC SYNE1 IKBKG ACTN4 DMD MYZAP OPA1 MADD HTT	1.03e-04	703	82	11	GO:0051640
GeneOntologyBiologicalProcess	vesicle cytoskeletal trafficking	KIFAP3 ACTN4 MADD HTT	1.47e-04	67	82	4	GO:0099518
GeneOntologyBiologicalProcess	synaptonemal complex assembly	SYCP1 SYCE1L SYCE2	2.05e-04	29	82	3	GO:0007130
GeneOntologyBiologicalProcess	non-motile cilium assembly	RPGRIP1L CEP250 CEP126 HTT	2.65e-04	78	82	4	GO:1905515
GeneOntologyBiologicalProcess	synaptonemal complex organization	SYCP1 SYCE1L SYCE2	2.76e-04	32	82	3	GO:0070193
GeneOntologyBiologicalProcess	cytoskeleton-dependent intracellular transport	KIFAP3 HOOK1 ACTN4 OPA1 MADD HTT	2.77e-04	225	82	6	GO:0030705
GeneOntologyBiologicalProcess	establishment of organelle localization	KIFAP3 CENPF INSC SYNE1 IKBKG ACTN4 OPA1 MADD HTT	3.15e-04	546	82	9	GO:0051656
GeneOntologyCellularComponent	microtubule organizing center	CFAP100 KIFAP3 RPGRIP1L CRACR2A HOOK1 CCDC42 CENPF CEP250 CNTRL ANKRD26 CHEK1 HMMR CEP126 CLIP1 CFAP53 HTT	4.67e-07	919	82	16	GO:0005815
GeneOntologyCellularComponent	cytoplasmic region	CFAP100 KIFAP3 RPGRIP1L CENPF INSC CNTRL CFAP53 OPA1 MADD HTT	1.44e-06	360	82	10	GO:0099568
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	CFAP100 KIFAP3 RPGRIP1L CENPF CNTRL CFAP53 OPA1 MADD HTT	4.20e-06	317	82	9	GO:0032838
GeneOntologyCellularComponent	centrosome	KIFAP3 RPGRIP1L HOOK1 CCDC42 CENPF CEP250 CNTRL ANKRD26 CHEK1 HMMR CEP126 CLIP1 CFAP53	8.87e-06	770	82	13	GO:0005813
GeneOntologyCellularComponent	condensed chromosome	KIFAP3 CENPF SYCP1 SGO2 CHEK1 CLIP1 SYCE1L SYCE2	2.74e-05	307	82	8	GO:0000793
GeneOntologyCellularComponent	condensed nuclear chromosome	KIFAP3 SYCP1 CHEK1 SYCE1L SYCE2	2.93e-05	91	82	5	GO:0000794
GeneOntologyCellularComponent	axoneme	CFAP100 KIFAP3 RPGRIP1L CENPF CNTRL CFAP53	1.64e-04	207	82	6	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	CFAP100 KIFAP3 RPGRIP1L CENPF CNTRL CFAP53	1.69e-04	208	82	6	GO:0097014
GeneOntologyCellularComponent	central element	SYCP1 SYCE2	4.19e-04	8	82	2	GO:0000801
GeneOntologyCellularComponent	spindle	KIFAP3 CENPF CEP250 CNTRL IKBKG HMMR CFAP53 TBL1X	5.19e-04	471	82	8	GO:0005819
GeneOntologyCellularComponent	synaptonemal complex	SYCP1 SYCE1L SYCE2	7.82e-04	46	82	3	GO:0000795
GeneOntologyCellularComponent	synaptonemal structure	SYCP1 SYCE1L SYCE2	7.82e-04	46	82	3	GO:0099086
GeneOntologyCellularComponent	ciliary basal body	CFAP100 KIFAP3 RPGRIP1L CENPF CEP250	1.02e-03	195	82	5	GO:0036064
GeneOntologyCellularComponent	spindle pole	CENPF CEP250 CNTRL IKBKG CFAP53	1.28e-03	205	82	5	GO:0000922
GeneOntologyCellularComponent	postsynapse	KIFAP3 SYNE1 ZMYND8 NGEF DOCK10 MACF1 ACTN4 EEA1 DMD MAPK10 HTT	2.04e-03	1018	82	11	GO:0098794
Domain	Actinin_actin-bd_CS	SYNE1 MACF1 ACTN4 DMD	2.73e-06	23	81	4	IPR001589
Domain	Spectrin	SYNE1 MACF1 ACTN4 DMD	2.73e-06	23	81	4	PF00435
Domain	ACTININ_2	SYNE1 MACF1 ACTN4 DMD	2.73e-06	23	81	4	PS00020
Domain	ACTININ_1	SYNE1 MACF1 ACTN4 DMD	2.73e-06	23	81	4	PS00019
Domain	Spectrin_repeat	SYNE1 MACF1 ACTN4 DMD	7.18e-06	29	81	4	IPR002017
Domain	Spectrin/alpha-actinin	SYNE1 MACF1 ACTN4 DMD	1.08e-05	32	81	4	IPR018159
Domain	SPEC	SYNE1 MACF1 ACTN4 DMD	1.08e-05	32	81	4	SM00150
Domain	DUF4200	CFAP100 CCDC42	1.11e-04	4	81	2	PF13863
Domain	DUF4200	CFAP100 CCDC42	1.11e-04	4	81	2	IPR025252
Domain	CH	SYNE1 MACF1 ACTN4 DMD	1.82e-04	65	81	4	SM00033
Domain	CH	SYNE1 MACF1 ACTN4 DMD	2.42e-04	70	81	4	PF00307
Domain	-	SYNE1 MACF1 ACTN4 DMD	2.56e-04	71	81	4	1.10.418.10
Domain	CH	SYNE1 MACF1 ACTN4 DMD	2.85e-04	73	81	4	PS50021
Domain	CH-domain	SYNE1 MACF1 ACTN4 DMD	3.16e-04	75	81	4	IPR001715
Domain	ARM-type_fold	DOCK2 KIFAP3 THADA INSC UTP20 EIF4G3 HTT	6.71e-04	339	81	7	IPR016024
Domain	DOCK_C	DOCK2 DOCK10	9.96e-04	11	81	2	IPR010703
Domain	DHR-1_domain	DOCK2 DOCK10	9.96e-04	11	81	2	IPR027007
Domain	DHR_2	DOCK2 DOCK10	9.96e-04	11	81	2	PS51651
Domain	DHR_1	DOCK2 DOCK10	9.96e-04	11	81	2	PS51650
Domain	DOCK-C2	DOCK2 DOCK10	9.96e-04	11	81	2	PF14429
Domain	DHR-2	DOCK2 DOCK10	9.96e-04	11	81	2	IPR027357
Domain	DHR-2	DOCK2 DOCK10	9.96e-04	11	81	2	PF06920
Domain	DOCK	DOCK2 DOCK10	9.96e-04	11	81	2	IPR026791
Domain	ARM-like	DOCK2 KIFAP3 INSC DOCK10 UTP20 HTT	1.13e-03	270	81	6	IPR011989
Domain	HEAT	UTP20 EIF4G3 HTT	2.04e-03	58	81	3	IPR000357
Domain	HEAT_REPEAT	UTP20 EIF4G3 HTT	3.49e-03	70	81	3	PS50077
Domain	Znf_FYVE_PHD	ZFYVE9 JADE2 ZMYND8 EEA1	3.83e-03	147	81	4	IPR011011
Domain	FYVE	ZFYVE9 EEA1	6.99e-03	29	81	2	PF01363
Domain	FYVE	ZFYVE9 EEA1	6.99e-03	29	81	2	SM00064
Pubmed	A human MAP kinase interactome.	JADE2 SYNE1 CEP250 CNTRL DUSP16 TNRC6A MACF1 ACTN4 DMD MAPK10 MADD MSI2	2.91e-09	486	86	12	20936779
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF280D CENPF TLE4 ZMYND8 TNRC6A IKBKG GEMIN5 CHEK1 TBL1X	9.76e-07	418	86	9	34709266
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SYNE1 CEP250 NGEF SYCP1 MACF1 EEA1 DMD	1.95e-06	234	86	7	36243803
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	KIFAP3 HOOK1 CENPF SYNE1 MACF1 DMD	2.14e-06	151	86	6	17043677
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	HOOK1 KIAA0825 CENPF SYNE1 CNTRL STARD10 GPS1 SANBR SYCP1 ANKRD26 MACF1 ACTN4 EEA1 DMD EIF4G3	2.34e-06	1442	86	15	35575683
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CUL2 KIFAP3 RNF214 THADA RPGRIP1L HOOK1 GPS1 ACTN4 PSMD9 CHEK1 HMMR EEA1 CLIP1 OPA1	4.28e-06	1321	86	14	27173435
Pubmed	Yeast two-hybrid screening identified WDR77 as a novel interacting partner of TSC22D2.	ANKRD36 MSH3 ITGA2 CLIP1	4.80e-06	45	86	4	27337956
Pubmed	The structure of the human betaII-tryptase tetramer: fo(u)r better or worse.	TPSAB1 TPSB2	6.04e-06	2	86	2	10500112
Pubmed	Characterization of a tryptase mRNA expressed in the human basophil cell line KU812.	TPSAB1 TPSB2	6.04e-06	2	86	2	8434231
Pubmed	Dose-dependent reduction of somatic expansions but not Htt aggregates by di-valent siRNA-mediated silencing of MSH3 in HdhQ111 mice.	MSH3 HTT	6.04e-06	2	86	2	38267530
Pubmed	Cloning and characterization of a second complementary DNA for human tryptase.	TPSAB1 TPSB2	6.04e-06	2	86	2	2203827
Pubmed	Characterization of two highly polymorphic human tryptase loci and comparison with a newly discovered monkey tryptase ortholog.	TPSAB1 TPSB2	6.04e-06	2	86	2	10898108
Pubmed	A possible role of tryptase in angiogenesis in the brain of mdx mouse, a model of Duchenne muscular dystrophy.	TPSAB1 DMD	6.04e-06	2	86	2	14706770
Pubmed	Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.	TPSAB1 TPSB2	6.04e-06	2	86	2	9521329
Pubmed	Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family.	TPSAB1 TPSB2	6.04e-06	2	86	2	2187193
Pubmed	Structural requirements and mechanism for heparin-dependent activation and tetramerization of human betaI- and betaII-tryptase.	TPSAB1 TPSB2	6.04e-06	2	86	2	15567416
Pubmed	Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft.	TPSAB1 TPSB2	6.04e-06	2	86	2	10391906
Pubmed	The human mast cell tryptase tetramer: a fascinating riddle solved by structure.	TPSAB1 TPSB2	6.04e-06	2	86	2	10708850
Pubmed	Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels.	TPSAB1 TPSB2	6.04e-06	2	86	2	17449330
Pubmed	Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia.	TPSAB1 TPSB2	6.04e-06	2	86	2	31337736
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	HOOK1 CENPF SYNE1 MACF1 DMD	1.25e-05	120	86	5	31413325
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	SYNE1 ANKRD26 MACF1	1.61e-05	20	86	3	21689717
Pubmed	NF-κB pathway controls mitochondrial dynamics.	IKBKG OPA1	1.81e-05	3	86	2	26024391
Pubmed	Essential Role of CFAP53 in Sperm Flagellum Biogenesis.	CCDC42 CFAP53	1.81e-05	3	86	2	34124066
Pubmed	THADA, SDHAF4, and MACF1 Gene Polymorphisms and Placental Expression in Women with Gestational Diabetes.	THADA MACF1	1.81e-05	3	86	2	36672824
Pubmed	Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity.	IKBKG HTT	1.81e-05	3	86	2	15371500
Pubmed	Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3.	TPSAB1 TPSB2	1.81e-05	3	86	2	9920877
Pubmed	Rare variants in MYD88, IRAK4 and IKBKG and susceptibility to invasive pneumococcal disease: a population-based case-control study.	IRAK4 IKBKG	1.81e-05	3	86	2	25886387
Pubmed	Systemic delivery of NEMO binding domain/IKKγ inhibitory peptide to young mdx mice improves dystrophic skeletal muscle histopathology.	IKBKG DMD	1.81e-05	3	86	2	21624467
Pubmed	Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations.	TPSAB1 TPSB2	1.81e-05	3	86	2	19748655
Pubmed	Real-time reverse linkage using polar body analysis for preimplantation genetic diagnosis in female carriers of de novo mutations.	IKBKG DMD	1.81e-05	3	86	2	19687056
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	RPGRIP1L CEP250 CNTRL ANKRD26 CLIP1	3.22e-05	146	86	5	21399614
Pubmed	Two novel proteins recruited by synaptonemal complex protein 1 (SYCP1) are at the centre of meiosis.	SYCP1 SYCE2	3.61e-05	4	86	2	15944401
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	MACF1 DMD	3.61e-05	4	86	2	8954775
Pubmed	MCU-independent Ca2+ uptake mediates mitochondrial Ca2+ overload and necrotic cell death in a mouse model of Duchenne muscular dystrophy.	DMD MCUB	3.61e-05	4	86	2	38514795
Pubmed	PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages.	IKBKG NLRP2	6.01e-05	5	86	2	15456791
Pubmed	Role of CLASP2 in microtubule stabilization and the regulation of persistent motility.	MACF1 CLIP1	6.01e-05	5	86	2	17113391
Pubmed	Persistent NF-κB activation in muscle stem cells induces proliferation-independent telomere shortening.	IKBKG DMD	6.01e-05	5	86	2	33979621
Pubmed	CCDC38 is required for sperm flagellum biogenesis and male fertility in mice.	CCDC42 CFAP53	6.01e-05	5	86	2	35587122
Pubmed	Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families.	TPSAB1 TPSB2	6.01e-05	5	86	2	10843716
Pubmed	GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation.	CENPF TNRC6A	6.01e-05	5	86	2	15494374
Pubmed	Dynamic localization of SMC5/6 complex proteins during mammalian meiosis and mitosis suggests functions in distinct chromosome processes.	SYCP1 SGO2	6.01e-05	5	86	2	23843628
Pubmed	Elucidation of synaptonemal complex organization by super-resolution imaging with isotropic resolution.	SYCP1 SYCE2	6.01e-05	5	86	2	25646409
Pubmed	SARA regulates neuronal migration during neocortical development through L1 trafficking.	ZFYVE9 EEA1	6.01e-05	5	86	2	27471254
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	CEP250 CNTRL UTP20 MCUB CLIP1 HTT	7.80e-05	285	86	6	32838362
Pubmed	Endosomal localization of FIP3/Arfophilin-1 and its involvement in dendritic formation of mouse hippocampal neurons.	IKBKG EEA1	9.01e-05	6	86	2	24576489
Pubmed	ANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cells.	ANKRD26 HMMR	9.01e-05	6	86	2	22666460
Pubmed	Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin.	MAPK10 HTT	9.01e-05	6	86	2	19525941
Pubmed	New developments in the genetics and activation of mast cell proteases.	TPSAB1 TPSB2	9.01e-05	6	86	2	12217407
Pubmed	The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO.	IKBKG OPA1	9.01e-05	6	86	2	23453807
Pubmed	Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.	CUL2 ZMYND8 HMMR ESCO1 MADD HTT	9.60e-05	296	86	6	34186245
Pubmed	Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6.	IRAK4 IKBKG	1.26e-04	7	86	2	16306937
Pubmed	Downregulation of integrins by von Hippel-Lindau (VHL) tumor suppressor protein is independent of VHL-directed hypoxia-inducible factor alpha degradation.	CUL2 ITGA2	1.26e-04	7	86	2	18523483
Pubmed	AGO4 regulates entry into meiosis and influences silencing of sex chromosomes in the male mouse germline.	SYCP1 SYCE2	1.26e-04	7	86	2	22863743
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	CUL2 TCAF1 MED9 TBC1D2 IKBKG CHEK1 KDSR MADD	1.28e-04	604	86	8	38803224
Pubmed	Placentation defects are highly prevalent in embryonic lethal mouse mutants.	RPGRIP1L ACTN4 CFAP53 TRUB2	1.28e-04	103	86	4	29539633
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	CENPF SYNE1 GPS1 SYCP1 SGO2 CHEK1 HMMR EEA1 CLIP1 ESCO1 TRUB2	1.30e-04	1155	86	11	20360068
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	MSH3 HMMR OPA1 HTT	1.33e-04	104	86	4	31240132
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	DOCK2 CENPF SYNE1 MACF1 DMD	1.33e-04	197	86	5	20811636
Pubmed	A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 alpha and beta MAPKs.	DUSP16 MAPK10	1.68e-04	8	86	2	11359773
Pubmed	A protein quality control pathway regulated by linear ubiquitination.	IKBKG HTT	1.68e-04	8	86	2	30886048
Pubmed	FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease.	MSH3 HTT	1.68e-04	8	86	2	34469738
Pubmed	3D-structured illumination microscopy provides novel insight into architecture of human centrosomes.	CEP250 CNTRL	1.68e-04	8	86	2	23213374
Pubmed	MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation.	MSH3 CHEK1	1.68e-04	8	86	2	14657349
Pubmed	A novel mouse synaptonemal complex protein is essential for loading of central element proteins, recombination, and fertility.	SYCP1 SYCE2	1.68e-04	8	86	2	21637789
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	CENPF SGO2 UTP20 HMMR CLIP1	1.79e-04	210	86	5	16565220
Pubmed	ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.	SYNE1 CNTRL ANKRD26 CLIP1	1.83e-04	113	86	4	34474245
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	CUL2 TCAF1 ZFYVE9 GPS1 IKBKG MACF1 ACTN4	1.94e-04	481	86	7	28190767
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	ADCY4 THADA ZNF280D CENPF SYNE1 GEMIN5 SGO2 UTP20 ACTN4 MSH3 EEA1 OPA1	1.98e-04	1425	86	12	30948266
Pubmed	Characterization of a novel meiosis-specific protein within the central element of the synaptonemal complex.	SYCP1 SYCE2	2.15e-04	9	86	2	16968740
Pubmed	The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1.	IRAK4 IKBKG	2.15e-04	9	86	2	17997719
Pubmed	Endotoxin tolerance impairs IL-1 receptor-associated kinase (IRAK) 4 and TGF-beta-activated kinase 1 activation, K63-linked polyubiquitination and assembly of IRAK1, TNF receptor-associated factor 6, and IkappaB kinase gamma and increases A20 expression.	IRAK4 IKBKG	2.15e-04	9	86	2	21220427
Pubmed	The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility.	SYCP1 SYCE2	2.15e-04	9	86	2	31437213
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	NGEF MACF1 EIF4G3 MAPK10 MADD HTT	2.27e-04	347	86	6	17114649
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	KIFAP3 LNX2 RPGRIP1L CEP250 ZMYND8 SGO2 ACTN4 MAPK10 CFAP53 ESCO1 TRUB2	2.43e-04	1242	86	11	30973865
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	EIF2D RPGRIP1L HOOK1 CEP250 CNTRL TNRC6A ANKRD26 ACTN4 CLIP1	2.62e-04	853	86	9	28718761
Pubmed	Inositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL function.	CUL2 GPS1	2.68e-04	10	86	2	26976604
Pubmed	ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity.	MACF1 CLIP1	2.68e-04	10	86	2	18854161
Pubmed	The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain.	CUL2 GPS1	2.68e-04	10	86	2	22956996
Pubmed	Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.	KIFAP3 TCAF1 LNX2 ZFYVE9 CRACR2A HOOK1 CCDC42 IRAK4 PSMD9 MSH3 HMMR DMD	2.75e-04	1477	86	12	31515488
Pubmed	DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.	CFAP100 KIAA0825 DUSP16 GPS1 NGEF HMMR	2.93e-04	364	86	6	31391242
Pubmed	TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.	IRAK4 IKBKG	3.93e-04	12	86	2	26831104
Pubmed	Brazilin selectively disrupts proximal IL-1 receptor signaling complex formation by targeting an IKK-upstream signaling components.	IRAK4 IKBKG	3.93e-04	12	86	2	24735611
Pubmed	miR-30 family microRNAs regulate myogenic differentiation and provide negative feedback on the microRNA pathway.	TNRC6A DMD	3.93e-04	12	86	2	25689854
Pubmed	Centrosome linker protein C-Nap1 maintains stem cells in mouse testes.	CEP250 SYCP1	3.93e-04	12	86	2	35599622
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	ANKRD36B RIN2 IRAK4 IKBKG ANKRD36 CHEK1 HMMR ANKRD36C MSI2	4.20e-04	910	86	9	36736316
Pubmed	Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes.	SYCP1 SYCE2	4.63e-04	13	86	2	22854038
Pubmed	A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation.	OPA1 TRUB2	4.63e-04	13	86	2	27667664
Pubmed	JADE2 Is Essential for Hippocampal Synaptic Plasticity and Cognitive Functions in Mice.	JADE2 DOCK10	4.63e-04	13	86	2	36008159
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SYNE1 TLE4 DOCK10 MACF1 OPA1 MADD	5.29e-04	407	86	6	12693553
Pubmed	Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder.	RPGRIP1L TLE4	5.39e-04	14	86	2	21254220
Pubmed	Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia.	CNTRL HMMR	5.39e-04	14	86	2	16112646
Pubmed	SCRE serves as a unique synaptonemal complex fastener and is essential for progression of meiosis prophase I in mice.	SYCP1 SYCE2	5.39e-04	14	86	2	30949703
Pubmed	Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.	DOCK2 DOCK10	5.39e-04	14	86	2	12432077
Pubmed	Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome.	CUL2 GPS1	5.39e-04	14	86	2	18173839
Pubmed	Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.	CUL2 GPS1	5.39e-04	14	86	2	31444342
Pubmed	Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis.	TLE4 MSI2	5.39e-04	14	86	2	15273690
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	EIF2D CENPF DOCK10 UTP20 ACTN4 OPA1	5.50e-04	410	86	6	26949251
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	SYNE1 MACF1 ESCO1 HTT	5.64e-04	152	86	4	34299191
Pubmed	Defining the membrane proteome of NK cells.	DOCK2 LRRC8C CRACR2A CNTRL DOCK10 GEMIN5 MSH3 HMMR KDSR OPA1	6.16e-04	1168	86	10	19946888
Interaction	SYCE1 interactions	CFAP100 HOOK1 CENPF CNTRL SYCP1 ANKRD26 HMMR EEA1 CLIP1	3.60e-09	127	86	9	int:SYCE1
Interaction	PCNT interactions	ADCY4 RPGRIP1L SYNE1 CNTRL DUSP16 MACF1 EIF4G3 MADD	8.85e-06	241	86	8	int:PCNT
Interaction	WHAMMP3 interactions	RPGRIP1L HOOK1 SYNE1 CEP250 CNTRL IKBKG	1.19e-05	119	86	6	int:WHAMMP3
Interaction	HAUS5 interactions	HOOK1 INSC CEP250 CNTRL DUSP16 HTT	2.55e-05	136	86	6	int:HAUS5
Interaction	N4BP2 interactions	RNF214 RPGRIP1L HOOK1 CEP250 DUSP16	3.94e-05	89	86	5	int:N4BP2
Interaction	KDM1A interactions	CFAP100 RPGRIP1L ZNF280D CENPF TLE4 ZMYND8 TNRC6A IKBKG GEMIN5 PSMD9 CHEK1 ESCO1 HTT TBL1X	4.19e-05	941	86	14	int:KDM1A
Interaction	MPHOSPH9 interactions	RNF214 RPGRIP1L CNTRL TNRC6A IKBKG	5.39e-05	95	86	5	int:MPHOSPH9
Interaction	SASH1 interactions	JADE2 IRAK4 IKBKG HTT	6.13e-05	50	86	4	int:SASH1
Interaction	HAUS3 interactions	RPGRIP1L HOOK1 CNTRL DUSP16 HTT	7.93e-05	103	86	5	int:HAUS3
Interaction	HAUS4 interactions	HOOK1 CNTRL DUSP16 DMD HTT	8.30e-05	104	86	5	int:HAUS4
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	CUL2 KIFAP3 ZFYVE9 CENPF TLE4 RIN2 ZMYND8 MACF1 UTP20 MSH3 HMMR DMD EIF4G3 CLIP1 OPA1 TBL1X	1.66e-08	856	86	16	M4500
Coexpression	HALLMARK_MITOTIC_SPINDLE	DOCK2 KIFAP3 CENPF CEP250 CNTRL ACTN4 CLIP1	4.23e-06	199	86	7	M5893
Coexpression	GEORGES_TARGETS_OF_MIR192_AND_MIR215	LRRC8C RPGRIP1L CENPF DUSP16 IRAK4 SANBR CUZD1 MACF1 SGO2 HMMR EEA1 OPA1 TBL1X	6.59e-06	892	86	13	M18120
Coexpression	HE_LIM_SUN_FETAL_LUNG_C4_CYCLING_T_CELL	ANKRD36B HOOK1 CENPF CNTRL ANKRD26 SGO2 ANKRD36 MSH3 CHEK1 HMMR ANKRD36C SYCE1L TBL1X	1.14e-05	939	86	13	M45768
Coexpression	GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_UP	RBM44 CENPF SGO2 CHEK1 HMMR SYCE2	3.56e-05	187	86	6	M2984
Coexpression	GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_1H_UP	ZFYVE9 NGEF ANKRD26 CEP126 EIF4G3 SYCE1L	4.90e-05	198	86	6	M9934
Coexpression	GSE27786_NKTCELL_VS_NEUTROPHIL_UP	THADA HOOK1 STARD10 ITGA2 KDSR TBL1X	5.18e-05	200	86	6	M4868
Coexpression	GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_IMMATURE_NEURON_CELL_LINE_DN	RNF214 EIF2D PAFAH2 CHEK1 HTT SYCE2	5.18e-05	200	86	6	M7428
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	LNX2 HOOK1 KIAA0825 CENPF TLE4 STARD10 DUSP16 SANBR ANKRD26 UTP20 DMD MAPK10 CCDC171 OPA1 MADD MSI2	1.80e-06	983	86	16	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	CUL2 RBM44 ZFYVE9 HOOK1 CENPF SYCP1 ANKRD26 SGO2 CHEK1 CCDC171 ESCO1 MADD HTT SYCE2	5.04e-06	820	86	14	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	HOOK1 KIAA0825 CENPF DUSP16 SANBR DMD CCDC171 OPA1 MADD	7.27e-06	328	86	9	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	KIFAP3 TCAF1 RPGRIP1L ZNF280D CENPF CXorf38 CEP250 ANKRD26 MACF1 MSH3 EEA1 CLIP1 OPA1	1.47e-05	780	86	13	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	RNF214 ZNF280D HOOK1 CENPF TLE4 CNTRL SANBR ANKRD26 MACF1 SGO2 HMMR CEP126 DMD CLIP1 MADD	2.10e-05	1060	86	15	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	ZNF280D HOOK1 CENPF IPCEF1 TLE4 CNTRL SANBR ANKRD26 MACF1 SGO2 UTP20 HMMR CEP126 DMD CLIP1 SYCE2	3.92e-05	1257	86	16	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500	RNF214 ZNF280D HOOK1 CCDC42 CENPF IPCEF1 TLE4 CNTRL SANBR ANKRD26 MACF1 SGO2 HMMR CEP126 DMD CLIP1 MADD	4.45e-05	1414	86	17	facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000	RBM44 THADA HOOK1 CENPF GEMIN5 UTP20 HMMR SYCE2	6.17e-05	333	86	8	gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_1000
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000	KIFAP3 RBM44 HOOK1 SYCP1 GEMIN5 CHEK1 EEA1 MAPK10 MCUB CFAP53 ESCO1 MSI2	6.19e-05	770	86	12	gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	KIFAP3 RBM44 TCAF1 HOOK1 TNRC6A SYCP1 GEMIN5 CHEK1 EEA1 MAPK10 ESCO1 MSI2	6.83e-05	778	86	12	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000	CUL2 RBM44 THADA HOOK1 CENPF SYCP1 GEMIN5 SGO2 UTP20 HMMR CCDC171 SYCE2	1.00e-04	810	86	12	gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_500	RBM44 HOOK1 ESCO1 MADD SYCE2	1.18e-04	118	86	5	gudmap_developingGonad_e14.5_ ovary_500_k3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4	ZNF280D CENPF ANKRD26 MACF1 CLIP1 OPA1	1.30e-04	192	86	6	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	ZFYVE9 ZNF280D HOOK1 TNRC6A SANBR MACF1 HMMR CLIP1 TBL1X SYCE2	1.45e-04	595	86	10	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_500	CUL2 RBM44 HOOK1 CENPF SYCP1 SGO2 UTP20 HMMR	1.74e-04	387	86	8	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	ZNF280D CENPF CXorf38 ANKRD26 MACF1 CLIP1 OPA1	1.80e-04	291	86	7	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_500	CUL2 RBM44 HOOK1 CENPF SYCP1 SGO2 UTP20 CCDC171	2.04e-04	396	86	8	gudmap_dev gonad_e13.5_M_GermCell_Oct_500
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	ZNF280D HOOK1 CENPF IPCEF1 TLE4 CNTRL SANBR ANKRD26 MACF1 SGO2 UTP20 HMMR CEP126 DMD CLIP1 SYCE2	2.24e-04	1459	86	16	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#3_top-relative-expression-ranked_1000	RBM44 HOOK1 SYCP1 GEMIN5	2.32e-04	74	86	4	gudmap_developingGonad_e14.5_ testes_1000_k3
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_500	CUL2 RBM44 HOOK1 CENPF SYCP1 SGO2 CHEK1 SYCE2	2.41e-04	406	86	8	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_500
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	RBM44 TCAF1 HOOK1 SYCP1 ANKRD26 GEMIN5 CHEK1 ESCO1 MADD MSI2 SYCE2	2.92e-04	776	86	11	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	HOOK1 KIAA0825 CENPF TLE4 DUSP16 SANBR ANKRD26 DMD OPA1 MADD	3.09e-04	654	86	10	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#4_top-relative-expression-ranked_200	RBM44 HOOK1 CENPF	3.51e-04	34	86	3	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k4_200
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000	CUL2 RBM44 HOOK1 CENPF TLE4 SYCP1 SGO2 UTP20 CHEK1 HMMR SYCE2	3.58e-04	795	86	11	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_200	RBM44 HOOK1 CENPF	3.82e-04	35	86	3	gudmap_dev gonad_e13.5_M_GermCell_Oct_k2_200
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_500	RBM44 HOOK1 CENPF CHEK1 SYCE2	3.84e-04	152	86	5	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_500
CoexpressionAtlas	geo_heart_top-relative-expression-ranked_500_k-means-cluster#5	TPSAB1 TPSB2	4.47e-04	8	86	2	geo_heart_500_K5
CoexpressionAtlas	B cells, preB.FrC.BM, CD19+ IgM- CD45R+ CD43+ HSA+, Bone marrow, avg-3	CENPF SGO2 CHEK1 HMMR	4.51e-04	88	86	4	GSM399452_100
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000	CUL2 RBM44 THADA HOOK1 CENPF SYCP1 SGO2 UTP20 CHEK1 HMMR SYCE2	4.74e-04	822	86	11	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	RPGRIP1L HOOK1 CENPF CEP250 SANBR ANKRD26 MSH3 EEA1 DMD CCDC171 CLIP1	5.19e-04	831	86	11	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	TCAF1 LNX2 ZNF280D HOOK1 CENPF SANBR ANKRD26 UTP20 DMD MAPK10 CCDC171 CLIP1	6.20e-04	989	86	12	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	RBM44 HOOK1 CENPF ANKRD26 CHEK1 ESCO1 SYCE2	6.58e-04	361	86	7	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_1000	CENPF SGO2 HMMR SYCE2	6.78e-04	98	86	4	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#1_top-relative-expression-ranked_1000	KIFAP3 ZNF280D HMMR MSI2	7.04e-04	99	86	4	gudmap_developingGonad_e14.5_ epididymis_1000_k1
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#4_top-relative-expression-ranked_500	CUL2 RBM44 HOOK1 CENPF	7.59e-04	101	86	4	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k4_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500	HOOK1 CENPF SANBR UTP20 DMD MAPK10 CCDC171 MSI2	8.68e-04	493	86	8	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_500	RBM44 HOOK1 SYCP1 CHEK1 ESCO1 MADD SYCE2	9.17e-04	382	86	7	gudmap_developingGonad_e14.5_ ovary_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	THADA ZNF280D MACF1 CLIP1 SYCE2	9.36e-04	185	86	5	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000_K3
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#4_top-relative-expression-ranked_1000	RBM44 HOOK1 GEMIN5 ESCO1	9.42e-04	107	86	4	gudmap_developingGonad_e16.5_ovary_1000_k4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5	ZFYVE9 ZNF280D CENPF SANBR MACF1 DMD CLIP1 TBL1X SYCE2	1.00e-03	629	86	9	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP100 RPGRIP1L KIAA0825 SYNE1 SANBR ANKRD26 CEP126 DMD MAPK10	1.69e-10	197	86	9	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	moderate-Epithelial-FOXN4+\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RPGRIP1L CENPF SANBR SGO2 ANKRD36 CEP126 ANKRD36C CCDC171	4.11e-09	194	86	8	5dffa578149104dda33774361e9e77b227b5f1ce
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	ANKRD36B CNTRL ANKRD26 ANKRD36 CEP126 EEA1 CLIP1 CFAP53	5.02e-09	199	86	8	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP100 KIAA0825 SYNE1 CEP126 DMD MAPK10 CFAP53	9.67e-08	193	86	7	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	ANKRD36B LAMB4 SYNE1 MACF1 ANKRD36 ANKRD36C	5.90e-07	156	86	6	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPGRIP1L KIAA0825 CENPF SANBR ANKRD26 CCDC171	6.12e-07	157	86	6	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	CCDC42 CENPF SGO2 CHEK1 HMMR SYCE2	6.60e-07	159	86	6	0fbfdb18b7ed4bde077add13f2b3636e144b254f
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	ANKRD36B LRRC8C DOCK10 MACF1 ANKRD36C MSI2	7.36e-07	162	86	6	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRRC8C ZFYVE9 TBC1D2 ITGA2 CFAP53 CLEC12B	1.08e-06	173	86	6	66488d01e03264fb193285470901c9c4182fbae8
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTRL DOCK10 MACF1 EIF4G3 MCUB CLIP1	1.45e-06	182	86	6	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 CENPF CNTRL DOCK10 SGO2 HMMR	1.70e-06	187	86	6	73931a5ea73799095daff100b5f18853c57c74dc
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD36B SYNE1 IPCEF1 DOCK10 MACF1 ANKRD36	1.86e-06	190	86	6	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C JADE2 SYNE1 RIN2 MACF1 CLIP1	1.98e-06	192	86	6	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP100 RPGRIP1L SYNE1 SANBR CEP126 MAPK10	2.10e-06	194	86	6	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	moderate-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CENPF CNTRL SANBR SGO2 ANKRD36 CCDC171	2.10e-06	194	86	6	dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	ANKRD36B IPCEF1 MACF1 ANKRD36 ANKRD36C	1.11e-05	151	86	5	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CENPF CCDC110 SGO2 CHEK1 HMMR	1.52e-05	161	86	5	0dd1401b4c990d49fccb702a9f9867590a58e203
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CENPF CCDC110 SGO2 CHEK1 HMMR	1.52e-05	161	86	5	b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CENPF CCDC110 SGO2 CHEK1 HMMR	1.52e-05	161	86	5	efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CENPF CCDC110 SGO2 CHEK1 HMMR	1.52e-05	161	86	5	28d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 TPSAB1 DOCK10 TPSB2 CLEC12B	1.66e-05	164	86	5	2c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF SYNE1 ANKRD36 HMMR MCUB	1.81e-05	167	86	5	1bd27ffe381d26731b6d4cc5f29b27f1bac4473b
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK2 RBM44 IPCEF1 CHEK1 MAPK10	1.81e-05	167	86	5	53e32d6687a07f486141df9f4ab998af4c03a507
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RBM44 CENPF SGO2 CHEK1 HMMR	1.81e-05	167	86	5	d21635df8b74189e3309eaf435af381fbe412574
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF SYNE1 ANKRD36 HMMR MCUB	1.87e-05	168	86	5	faaba5ac01c2ebe380f56559374a121979a85a13
ToppCell	Control-T_cells-Tregs\|Control / group, cell type (main and fine annotations)	DOCK2 IPCEF1 DUSP16 DOCK10 MSI2	1.92e-05	169	86	5	e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCell	Dividing_Macrophages-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	CENPF SGO2 CHEK1 HMMR SYCE2	1.92e-05	169	86	5	bc859a103cad567caf50c3c3882d2d2017807c73
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RBM44 CENPF DOCK10 SGO2 HMMR	2.03e-05	171	86	5	845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SYNE1 DUSP16 MACF1 ANKRD36 ANKRD36C	2.03e-05	171	86	5	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	wk_20-22-Hematologic-Myeloid-Eosinophil\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	TPSAB1 IPCEF1 HMMR TPSB2 SYCE2	2.03e-05	171	86	5	fa6e856e62b82ec4972e0098e73f237cc611891f
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF SGO2 CHEK1 HMMR SYCE2	2.09e-05	172	86	5	35c20de4db47dbf31c857d23c7a25cd7f95c085c
ToppCell	10x5'-bone_marrow-Lymphocytic_NK-Cycling_NK\|bone_marrow / Manually curated celltypes from each tissue	CENPF SGO2 CHEK1 HMMR SYCE2	2.15e-05	173	86	5	8a9dd85f718564c07cf3120ad648daeb60c94fc5
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 LNX2 CRACR2A MYZAP NLRP2	2.27e-05	175	86	5	43be63976da5ad0764d24d90919a77ce46068f52
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFAP100 CENPF SGO2 CHEK1 SYCE2	2.27e-05	175	86	5	73f25bd54309aed1480ddc44bdab518b17e71f92
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4\|Striatum / BrainAtlas - Mouse McCarroll V32	CENPF SGO2 CHEK1 HMMR SYCE2	2.33e-05	176	86	5	d70fdc7bc48719776ed1e7c01118385e3a21623f
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_1\|Striatum / BrainAtlas - Mouse McCarroll V32	CENPF SGO2 CHEK1 HMMR SYCE2	2.33e-05	176	86	5	a84361308e5e96f3a30246cd29e109c321ee65bf
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CENPF SGO2 CHEK1 HMMR SYCE2	2.33e-05	176	86	5	b17317ac41d3215db55a38cbd3366c0947f7a2a3
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD36B IPCEF1 MACF1 ANKRD36C MSI2	2.53e-05	179	86	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	10x5'-blood-Lymphocytic_NK-Cycling_NK\|blood / Manually curated celltypes from each tissue	CENPF SGO2 CHEK1 HMMR SYCE2	2.53e-05	179	86	5	c93711273055a999335ba8d0f6500e4549f46cec
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CENPF SGO2 CHEK1 HMMR SYCE2	2.67e-05	181	86	5	73b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCell	LV-17._Lymphocyte\|LV / Chamber and Cluster_Paper	DOCK2 TPSAB1 DOCK10 MCUB TPSB2	2.67e-05	181	86	5	81fafa69c8c240250a667a5f3b321e8be1b9a288
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CENPF SGO2 CHEK1 HMMR SYCE2	2.81e-05	183	86	5	6c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTRL DOCK10 MACF1 EIF4G3 CLIP1	2.89e-05	184	86	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	COVID-19_Moderate-HSPC\|World / disease group, cell group and cell class	TPSAB1 CCDC42 CCDC171 TPSB2 MSI2	2.89e-05	184	86	5	ccc93babe1fcdeb66b78e1d8414357877a7c45bd
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD36B CRACR2A STARD10 ANKRD36 ANKRD36C	2.89e-05	184	86	5	01c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CENPF CCDC110 SGO2 ANKRD36 HMMR	2.96e-05	185	86	5	ff598af88c7f9d7224cc4ed96b1c3463ef76b550
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNTRL DOCK10 MACF1 EIF4G3 CLIP1	2.96e-05	185	86	5	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP100 KIAA0825 CEP126 MAPK10 CFAP53	3.28e-05	189	86	5	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	THADA MACF1 ANKRD36C ESCO1 MSI2	3.36e-05	190	86	5	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CENPF SGO2 ANKRD36 ANKRD36C CCDC171	3.36e-05	190	86	5	0adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD36B CRACR2A STARD10 ANKRD36 ANKRD36C	3.36e-05	190	86	5	23f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCell	NS-moderate-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPGRIP1L CENPF SANBR SGO2 CCDC171	3.36e-05	190	86	5	250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell	normal_Pleural_Fluid-T/NK_cells-Undetermined\|normal_Pleural_Fluid / Location, Cell class and cell subclass	CENPF SGO2 CHEK1 HMMR SYCE2	3.36e-05	190	86	5	165c61443ff0c8efbdad3b052bb00f46d81c5203
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CENPF SGO2 ANKRD36 ANKRD36C CCDC171	3.36e-05	190	86	5	05455775845f4ded5c27e7b83242078d23162aaf
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD36B CRACR2A STARD10 ANKRD36 ANKRD36C	3.36e-05	190	86	5	3c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T\|bone_marrow / Manually curated celltypes from each tissue	LAMB4 CENPF SGO2 CHEK1 HMMR	3.45e-05	191	86	5	210a0f1a71df2508cbfc73d6868a2122338b9a1c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 CENPF SGO2 CHEK1 HMMR	3.45e-05	191	86	5	ff2cc4c10aa584b3daeaaf23cd8ee09bdbdf684d
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK2 CENPF SGO2 CHEK1 HMMR	3.45e-05	191	86	5	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CENPF SGO2 CHEK1 HMMR SYCE2	3.45e-05	191	86	5	b85a0978dc1e8af4f49423f56dcfd52efce09ed1
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ANKRD36B DOCK10 MACF1 ANKRD36 ANKRD36C	3.54e-05	192	86	5	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	facs-Thymus-Flowthrough-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF SGO2 CHEK1 HMMR SYCE2	3.54e-05	192	86	5	e8d47504b744040a762ec9b670a66cc060b2ae86
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	IPCEF1 TNRC6A MACF1 MAPK10 MSI2	3.54e-05	192	86	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	(1)_T_cells_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CENPF SGO2 CHEK1 HMMR SYCE2	3.71e-05	194	86	5	8f313071933451780309d2174ed27d8cdc734343
ToppCell	Dividing_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	CENPF SGO2 CHEK1 HMMR SYCE2	3.81e-05	195	86	5	79ee423df85aa1631b7bdea74eacaf826dfc4a2c
ToppCell	Dividing_cells-Dividing_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	CENPF SGO2 CHEK1 HMMR SYCE2	3.81e-05	195	86	5	19829760dfcc0edafd2a2bd80f424a45d039af1f
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	JADE2 DUSP16 MACF1 ANKRD36 ANKRD36C	3.81e-05	195	86	5	4bdedd924564a260841a9153604026b57487c83d
ToppCell	COVID-19-kidney-Proliferating_T_cell\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK2 CENPF DOCK10 SGO2 HMMR	3.81e-05	195	86	5	7e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCell	(1)_T_cells-(1)_T_cells_Dividing\|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	CENPF SGO2 CHEK1 HMMR SYCE2	3.81e-05	195	86	5	cf00a0b4f341f0487d5b37810abe2952fdd3f6f2
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_1\|343B / Donor, Lineage, Cell class and subclass (all cells)	CENPF SGO2 CHEK1 HMMR SYCE2	3.81e-05	195	86	5	47a01b8a92eebeb34ac7f70bf1ab4613a326e24f
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CENPF SGO2 CHEK1 HMMR SYCE2	3.90e-05	196	86	5	6d80e23f6a1725a3f5ea7263233c55c2ea56f977
ToppCell	BAL-Control-Myeloid-Myeloid\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CENPF SGO2 CHEK1 HMMR SYCE2	3.90e-05	196	86	5	bf1d3fae8c01bb3d17c2dafad92b94937c663acd
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CENPF SGO2 CHEK1 HMMR SYCE2	3.90e-05	196	86	5	3dd7ed1dfac8d90c8a44f0ae00128bb46d9ef496
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CENPF SGO2 CHEK1 HMMR SYCE2	3.90e-05	196	86	5	4f649e3bfd21f21682678828673843a7d51c4ff2
ToppCell	BAL-Control-Myeloid-Myeloid\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CENPF SGO2 CHEK1 HMMR SYCE2	3.90e-05	196	86	5	799c290fb3dfacb666dd0dc3c43ec8a86b697ec7
ToppCell	IPF-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	LRRC8C DUSP16 DOCK10 ITGA2 MCUB	3.90e-05	196	86	5	6e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CENPF SGO2 CHEK1 HMMR SYCE2	3.90e-05	196	86	5	0c003a767c3b58605099dab64b9df0d8e5d8bc4b
ToppCell	COVID_non-vent-Lymphocytic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	JADE2 SYNE1 MACF1 ANKRD36 ANKRD36C	4.00e-05	197	86	5	c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell	Mild_COVID-19-T/NK-proliferating_T/NK\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	CENPF SGO2 CHEK1 HMMR SYCE2	4.00e-05	197	86	5	5fd52fba2cb6fa67377f873da2ff6ce9c83b0591
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 MACF1 ANKRD36 ANKRD36C MSI2	4.00e-05	197	86	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Control-Myeloid-proliferating_Myeloid_cells\|Control / Disease group,lineage and cell class （2021.01.30）	CENPF SGO2 CHEK1 HMMR SYCE2	4.00e-05	197	86	5	ddbe3fe078766bb55f0d7ca1aeb8f9e4aa696d8e
ToppCell	Healthy_Control-Lymphoid-T-Proliferating_T\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CENPF SGO2 CHEK1 HMMR SYCE2	4.00e-05	197	86	5	3ce3dcbbe0edeb5a6fb5596dd6c2b4d6c1d5159d
ToppCell	proximal-Hematologic-Proliferating_Macrophage\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPF SGO2 CHEK1 HMMR SYCE2	4.00e-05	197	86	5	0b1fa881abbfcc54b322fc27124db3f8947af016
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	CENPF SGO2 CHEK1 HMMR SYCE2	4.00e-05	197	86	5	434a5686a103bb766e0d80038413f0e12ea3981a
ToppCell	Mild-Lymphoid-T-Proliferating_T\|Mild / Condition, Lineage, Cell class and cell subclass	CENPF SGO2 CHEK1 HMMR SYCE2	4.00e-05	197	86	5	794517c70089da109f4c6489fe406c0ba6882b76
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	CENPF SGO2 CHEK1 HMMR SYCE2	4.00e-05	197	86	5	6bddfa199ca812d9e518eaa02c3d4fb67e9f5b16
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CENPF SGO2 CHEK1 HMMR SYCE2	4.00e-05	197	86	5	c0a71a9452febda433bc544e4ac0a79c43dcf13e
ToppCell	distal-Hematologic-Proliferating_NK/T-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPF SGO2 CHEK1 HMMR SYCE2	4.00e-05	197	86	5	04b10879e48c101d1de449db0bc6b6484090b965
ToppCell	proximal-3-Hematologic-Proliferating_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPF SGO2 CHEK1 HMMR SYCE2	4.00e-05	197	86	5	0dd9058aa19d1268ebba9a65555870224b5a5978
ToppCell	proximal-Hematologic-Proliferating_Macrophage-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPF SGO2 CHEK1 HMMR SYCE2	4.00e-05	197	86	5	9243617b307acf3df40d93c41cd8d4788699a7ea
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 TLE4 MACF1 PSMD9 ANKRD36	4.09e-05	198	86	5	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFAP100 SYNE1 CNTRL CEP126 CFAP53	4.09e-05	198	86	5	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	distal-2-Hematologic-Proliferating_NK/T\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPF SGO2 CHEK1 HMMR SYCE2	4.09e-05	198	86	5	a5fd710df5669c95fc5b5ef6e5cfafe6687c7b72
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	CENPF SGO2 CHEK1 HMMR SYCE2	4.09e-05	198	86	5	6a10bb81817ab606f1f5a2bd8cfe77ef2fb3f2fb
ToppCell	Caecum-(1)_T_cell-(18)_cycling_gd_T\|Caecum / shred on region, Cell_type, and subtype	CENPF CHEK1 HMMR ITGA2 SYCE2	4.09e-05	198	86	5	64278d8831c81874937e76b561c53928dfc437c5
ToppCell	medial-2-Hematologic-Proliferating_Macrophage\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPF SGO2 CHEK1 HMMR SYCE2	4.09e-05	198	86	5	64a2bcf5a9ba66a4fe08fbde33f1886c136cde8f
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CENPF SGO2 CHEK1 HMMR SYCE2	4.09e-05	198	86	5	428182c71f009906c581e02257e545ea5fb99650
ToppCell	critical-Epithelial-FOXN4+\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	HOOK1 CENPF SGO2 ANKRD36 CCDC171	4.09e-05	198	86	5	6b160b3d6a2c1b1641c2c7dcec1a7ef38411fec9
ToppCell	medial-Hematologic-Proliferating_Macrophage-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPF SGO2 CHEK1 HMMR SYCE2	4.09e-05	198	86	5	fcc14ac3eb5088b9d6cd6af5a34dee5b81c0ece8
ToppCell	distal-1-Hematologic-Proliferating_Macrophage\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPF SGO2 CHEK1 HMMR SYCE2	4.09e-05	198	86	5	df3f5559ecd1f3cd1fd60e39dbad8741309e83a3
ToppCell	distal-Hematologic-Proliferating_Macrophage-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CENPF SGO2 CHEK1 HMMR SYCE2	4.09e-05	198	86	5	8afeb1f9bc9d8551482c8fefe4c5f88d9cd13ee2
Drug	Resveratrol [501-36-0]; Down 200; 17.6uM; MCF7; HT_HG-U133A	CENPF CNTRL PAFAH2 CUZD1 MSH3 CHEK1 HMMR CLIP1	6.69e-07	192	86	8	2865_DN
Drug	2g6p	TPSAB1 ADCY4 IKBKG TPSB2	1.27e-05	38	86	4	CID002740174
Drug	topsentin	SYNE1 ITGA2	1.41e-05	2	86	2	CID000072457
Drug	ethylene oxide	TPSAB1 SYNE1 ITGA2 TPSB2	1.41e-05	39	86	4	CID000006354
Disease	migraine disorder	THADA CENPF INSC ZMYND8 MACF1 ACTN4 ANKRD36C DMD MAPK10	9.21e-07	357	85	9	MONDO_0005277
Disease	cerebellar ataxia (is_implicated_in)	RPGRIP1L SYNE1	8.15e-05	5	85	2	DOID:0050753 (is_implicated_in)
Disease	tryptase beta-2 measurement	TPSAB1 TPSB2	2.91e-04	9	85	2	EFO_0008306
Disease	pneumococcal bacteremia	DOCK2 LAMB4	4.44e-04	11	85	2	EFO_1001925
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	HOOK1 SYNE1	5.31e-04	12	85	2	DOID:11726 (implicated_via_orthology)
Disease	mean platelet volume	LRRC8C LNX2 STARD10 ZMYND8 TNRC6A DOCK10 ACTN4 ITGA2 HTT MSI2	6.98e-04	1020	85	10	EFO_0004584
Disease	basophil measurement	TPSAB1 THADA TPSB2	7.01e-04	60	85	3	EFO_0803539
Disease	nucleotide measurement	DOCK2 ITGA2 MAPK10	1.24e-03	73	85	3	EFO_0010513
Disease	bipolar disorder	DOCK2 JADE2 INSC SYNE1 TLE4 ZMYND8 NGEF	1.40e-03	577	85	7	MONDO_0004985
Disease	platelet component distribution width	LNX2 JADE2 SYNE1 RIN2 ZMYND8 DOCK10 MACF1 ITGA2	1.51e-03	755	85	8	EFO_0007984
Disease	urticaria	TPSAB1 TPSB2	1.51e-03	20	85	2	EFO_0005531
Disease	age at menarche	IQANK1 JADE2 INSC TNRC6A EIF4G3 MADD SYCE2	1.65e-03	594	85	7	EFO_0004703
Disease	age at menopause	TLE4 DOCK10 GEMIN5 OPA1 MSI2	1.83e-03	302	85	5	EFO_0004704
Disease	response to peginterferon alfa-2a	ANKRD26 MSI2	2.36e-03	25	85	2	EFO_0010103
Disease	thrombocytopenia (is_implicated_in)	ANKRD26 ITGA2	2.75e-03	27	85	2	DOID:1588 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
VEKKKQIQHVCQEME	ZNF280D	836	Q6N043
QLRHCMSKQAEVLIK	CNTRL	2251	Q7Z7A1
DCILEKNEQHTVMKL	EIF2D	441	P41214
LVIQYTVKHEQKMDC	CALR3	91	Q96L12
NIKKEICINKMLNHE	CHEK1	51	O14757
ICINKMLNHENVVKF	CHEK1	56	O14757
CSELQEELVMAKKHQ	CCDC171	396	Q6TFL3
QEIAEKNMEKLNHIE	CCDC171	686	Q6TFL3
ICKVLAVNQENEHLM	ACTN4	281	O43707
DQIAKEHECMRIKIL	ADCY4	306	Q8NFM4
LQQEACKLHQEKEME	CRACR2A	336	Q9BSW2
NVILLIDQHEMKCKD	ANKRD36	1351	A6QL64
NCKNVILLIDQHEMK	ANKRD36B	786	Q8N2N9
KMLVNELNHSKEKEC	ANKRD36B	1216	Q8N2N9
LVEHCQKLEEQMNKL	DMD	1036	P11532
VRCAEKMQDHKQKLE	ANKRD26	1281	Q9UPS8
ANKERELKCQHMQEL	CCDC42	111	Q96M95
CQKIMQRAIKAELHL	RBM44	596	Q6ZP01
KVCEIHFHEINNKMV	MSI2	166	Q96DH6
NCKNVILLIDQHEMK	ANKRD36C	1211	Q5JPF3
YIEMKQQHKDAVLCV	MSH3	236	P20585
MHNQVFIELNHIKKC	MADD	1571	Q8WXG6
HSLCLQMQVEELNEK	MCUB	321	Q9NWR8
EQKINTMVLDLCHKP	KIAA0825	1121	Q8IV33
ELVLMKCVNHKNIIS	MAPK10	111	P53779
MIEQLQEKVHELEKQ	RPGRIP1L	111	Q68CZ1
KDVMQRCDLEAHLKN	LNX2	121	Q8N448
ICKLQEQIFHLQMKL	JADE2	496	Q9NQC1
KHVINMCLNVIKVSV	GPS1	196	Q13098
EHLKRCQQQMAEDKA	IKBKG	126	Q9Y6K9
HCRNLQKMSLQVIKE	NLRP2	646	Q9NX02
MLKAVIDQCNHDNIL	ITGA2	291	P17301
MKQLCLCVEQHVKEN	MACF1	771	Q9UPN3
NIIKCMDKDSPEVHQ	MED9	71	Q9NWA0
LHQKLCSFQEEMVKE	HMMR	356	O75330
CVHNETKNELEKMLK	OPA1	786	O60313
TKNELEKMLKCNEEH	OPA1	791	O60313
KMCLDKVQEVLSTHQ	CFAP53	481	Q96M91
EKTCKELKHQLQVQM	EEA1	891	Q15075
EMFILVLQQCHKENE	HTT	1586	P42858
LKCKEHDLAMINQLL	IPCEF1	366	Q8WWN9
CKNLLNVEKIHAIMS	DOCK10	886	Q96BY6
KELLEQKDDMQHQVL	DOCK2	866	Q92608
DQKHQKEIENMCLKT	CENPF	711	P49454
HQKQLLSKINCEKEM	CEP126	186	Q9P2H0
HILEAININCSKLMK	DUSP16	41	Q9BY84
ELEENHHKMECQQKL	CEP250	1561	Q9BV73
HHKMECQQKLIKELE	CEP250	1566	Q9BV73
ECHNIIRQEKKNDMA	CUL2	281	Q13617
EEKLQMQKILQEEHL	CFAP100	546	Q494V2
LQVENEHVLKSMKAC	INSC	201	Q1MX18
ELVKIQKHMQLCEDY	LAMB4	1521	A4D0S4
EDMQKLDSLCLHQKL	CXorf38	291	Q8TB03
TKLHDRNITCQQEKM	ESCO1	441	Q5FWF5
DQEIKVMAKCQHENL	IRAK4	231	Q9NWZ3
CEKKQEHIQNIMTLE	HOOK1	131	Q9UJC3
QKQLQIIVKCEMGHN	CUZD1	356	Q86UP6
QIAKVVIKICEHEMN	ZMYND8	236	Q9ULU4
TEAIMHDCVVKLLKN	EIF4G3	906	O43432
IEMHSINDKQVVLCI	KDSR	76	Q06136
LEKKMETSHNQCQEL	CLIP1	1011	P30622
LMHDKNNEIRKVCDN	KIFAP3	641	Q92845
VNLMKKICAQHEQSR	PAFAH2	291	Q99487
CLQNDHKAVMKQVEE	PSMD9	81	O00233
LHQDQMVQKITLDCI	UTP20	946	O75691
KQVKVPIMENHICDA	TPSAB1	176	Q15661
KQVKVPIMENHICDA	TPSB2	176	P20231
KKEMQVAALTICHQD	THADA	6	Q6YHU6
VQAVEMDRTLHKIKC	STARD10	56	Q9Y365
QEHEKMCQQLERQLK	SYNE1	4781	Q8NF91
IMCHLESVQELINEK	TCAF1	731	Q9Y4C2
LDAHKELEMVVKACN	NGEF	441	Q8N5V2
KLECQDIINKHYMEV	SGO2	951	Q562F6
QEALRILQMHCQEKE	SYCE1L	101	A8MT33
LKCQVTELHDVLMKD	IQANK1	406	A8MXQ7
MAKISHLETELKQVC	SYCE2	136	Q6PIF2
NMVIHVCDEAKNLKE	SANBR	146	Q6NSI8
ICHSIKQMKEELQKS	CCDC110	241	Q8TBZ0
EQMAIKLCQELIIHT	CLEC12B	121	Q2HXU8
MKQEVCIHDLQAHNK	TBL1X	441	O60907
EEEMKNHQEILKAIQ	RNF214	266	Q8ND24
FECNVEMLKQAVKDH	UHRF1BP1L	396	A0JNW5
QIDVVLEKAMHKCIL	RIN2	586	Q8WYP3
MHKQAEIVKRLNAIC	TLE4	81	Q04727
QKEIDKRCQHKIAEM	SYCP1	696	Q15431
LAEMIRQHQKSQLCK	GEMIN5	1381	Q8TEQ6
QCMHETQKELRKLVH	TRUB2	226	O95900
KEEVVKAQKSLHMCV	TNRC6A	1826	Q8NDV7
KNVLVVAVMHNCDKR	ZFYVE9	146	O95405
LLMDKNHAKQQVICK	TBC1D2	406	Q9BYX2
KKMTNLTELELVHCD	LRRC8C	586	Q8TDW0
HCQQKKVKQMVEEIE	MYZAP	361	P0CAP1