Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	carnitine transmembrane transporter activity	SLC22A16 SLC22A4 SLC22A5	9.69e-07	6	74	3	GO:0015226
GeneOntologyMolecularFunction	fatty acid ligase activity	ACSM4 ACSM3 ACSM5 SLC27A5	2.44e-06	26	74	4	GO:0015645
GeneOntologyMolecularFunction	fatty-acyl-CoA synthase activity	ACSM4 ACSM3 ACSM5	2.70e-06	8	74	3	GO:0004321
GeneOntologyMolecularFunction	CoA-ligase activity	ACSM4 ACSM3 ACSM5 SLC27A5	2.86e-06	27	74	4	GO:0016405
GeneOntologyMolecularFunction	acid-thiol ligase activity	ACSM4 ACSM3 ACSM5 SLC27A5	5.07e-06	31	74	4	GO:0016878
GeneOntologyMolecularFunction	medium-chain fatty acid-CoA ligase activity	ACSM4 ACSM3 ACSM5	7.89e-06	11	74	3	GO:0031956
GeneOntologyMolecularFunction	ligase activity, forming carbon-sulfur bonds	ACSM4 ACSM3 ACSM5 SLC27A5	1.59e-05	41	74	4	GO:0016877
GeneOntologyMolecularFunction	quaternary ammonium group transmembrane transporter activity	SLC22A16 SLC22A4 SLC22A5	2.15e-05	15	74	3	GO:0015651
GeneOntologyMolecularFunction	corticotropin-releasing hormone receptor activity	CRHR1 CRHR2	4.05e-05	3	74	2	GO:0043404
GeneOntologyMolecularFunction	corticotrophin-releasing factor receptor activity	CRHR1 CRHR2	4.05e-05	3	74	2	GO:0015056
GeneOntologyMolecularFunction	C-acyltransferase activity	ACSM4 ACSM3 ACSM5	6.19e-05	21	74	3	GO:0016408
GeneOntologyMolecularFunction	amino-acid betaine transmembrane transporter activity	SLC22A4 SLC22A5	8.09e-05	4	74	2	GO:0015199
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	GIPR NPBWR1 OR11G2 OR11H1 IL1R2 INSRR TAS2R41 OR11H12 GPR88 CR1 ACKR1 OR11H2 FCAMR CRHR1 CRHR2	1.10e-04	1353	74	15	GO:0004888
GeneOntologyMolecularFunction	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	FUT4 FUT5	2.01e-04	6	74	2	GO:0017083
GeneOntologyMolecularFunction	modified amino acid transmembrane transporter activity	SLC22A16 SLC22A4 SLC22A5	2.46e-04	33	74	3	GO:0072349
GeneOntologyMolecularFunction	monocarboxylic acid transmembrane transporter activity	ABCC3 CEACAM8 SLC16A11 SLC27A5	3.49e-04	90	74	4	GO:0008028
GeneOntologyMolecularFunction	alpha-(1->3)-fucosyltransferase activity	FUT4 FUT5	3.74e-04	8	74	2	GO:0046920
GeneOntologyMolecularFunction	G protein-coupled receptor activity	GIPR NPBWR1 OR11G2 OR11H1 TAS2R41 OR11H12 GPR88 ACKR1 OR11H2 CRHR1 CRHR2	3.92e-04	884	74	11	GO:0004930
GeneOntologyMolecularFunction	peptide hormone binding	GIPR CRHR1 CRHR2	1.12e-03	55	74	3	GO:0017046
GeneOntologyMolecularFunction	fucosyltransferase activity	FUT4 FUT5	1.20e-03	14	74	2	GO:0008417
GeneOntologyMolecularFunction	transmembrane transporter activity	ABCC3 CATSPER2 SLC22A16 SLC22A4 SLC22A5 SLC25A14 CEACAM8 SLC16A11 AQP7P3 SLC4A4 ATP2A1 SLC27A5	1.25e-03	1180	74	12	GO:0022857
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	GIPR NPBWR1 CRHR1 CRHR2	1.51e-03	133	74	4	GO:0008528
GeneOntologyMolecularFunction	peptide receptor activity	GIPR NPBWR1 CRHR1 CRHR2	1.82e-03	140	74	4	GO:0001653
GeneOntologyMolecularFunction	active transmembrane transporter activity	ABCC3 SLC22A4 SLC22A5 SLC25A14 SLC16A11 SLC4A4 ATP2A1	1.92e-03	477	74	7	GO:0022804
GeneOntologyMolecularFunction	ATP-dependent activity	ABCC3 ACSM4 ACSM3 ZCWPW2 DNAH2 ACSM5 ATP2A1 SLC27A5	1.93e-03	614	74	8	GO:0140657
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	ABCC3 CEACAM8 AQP7P3	2.24e-03	70	74	3	GO:1901618
GeneOntologyMolecularFunction	symporter activity	SLC22A4 SLC22A5 SLC16A11 SLC4A4	2.34e-03	150	74	4	GO:0015293
GeneOntologyMolecularFunction	lipid transmembrane transporter activity	ABCC3 CEACAM8 SLC27A5	2.52e-03	73	74	3	GO:0170055
GeneOntologyMolecularFunction	transporter activity	ABCC3 CATSPER2 SLC22A16 SLC22A4 SLC22A5 SLC25A14 CEACAM8 SLC16A11 AQP7P3 SLC4A4 ATP2A1 SLC27A5	2.63e-03	1289	74	12	GO:0005215
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC22A16 SLC22A4 SLC22A5	3.63e-03	83	74	3	GO:0015101
GeneOntologyMolecularFunction	ligase activity	ACSM4 ACSM3 ACSM5 SLC27A5	3.99e-03	174	74	4	GO:0016874
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	ABCC3 CEACAM8 SLC16A11 SLC4A4 SLC27A5	4.64e-03	293	74	5	GO:0008514
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC22A4 SLC22A5 SLC25A14 SLC16A11 SLC4A4	4.84e-03	296	74	5	GO:0015291
GeneOntologyMolecularFunction	solute:inorganic anion antiporter activity	SLC25A14 SLC4A4	6.25e-03	32	74	2	GO:0005452
GeneOntologyMolecularFunction	hormone binding	GIPR CRHR1 CRHR2	6.63e-03	103	74	3	GO:0042562
GeneOntologyMolecularFunction	bile acid transmembrane transporter activity	ABCC3 CEACAM8	7.04e-03	34	74	2	GO:0015125
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	ABCC3 SLC22A5	7.04e-03	34	74	2	GO:0042910
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	ABCC3 CEACAM8 SLC16A11 SLC27A5	7.33e-03	207	74	4	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	ABCC3 CEACAM8 SLC16A11 SLC27A5	7.46e-03	208	74	4	GO:0005342
GeneOntologyBiologicalProcess	carnitine transmembrane transport	SLC22A16 SLC22A4 SLC22A5	1.54e-06	7	74	3	GO:1902603
GeneOntologyBiologicalProcess	carnitine transport	SLC22A16 SLC22A4 SLC22A5	3.67e-06	9	74	3	GO:0015879
GeneOntologyBiologicalProcess	organic cation transport	COMT SLC22A16 SLC22A4 SLC22A5 CRHR1 CRHR2	1.36e-05	145	74	6	GO:0015695
GeneOntologyBiologicalProcess	amino-acid betaine transport	SLC22A16 SLC22A4 SLC22A5	1.57e-05	14	74	3	GO:0015838
GeneOntologyBiologicalProcess	quaternary ammonium group transport	SLC22A16 SLC22A4 SLC22A5	4.12e-05	19	74	3	GO:0015697
GeneOntologyBiologicalProcess	positive regulation of cAMP-mediated signaling	GIPR CRHR1 CRHR2	7.46e-05	23	74	3	GO:0043950
GeneOntologyBiologicalProcess	cellular response to corticotropin-releasing hormone stimulus	CRHR1 CRHR2	1.89e-04	6	74	2	GO:0071376
GeneOntologyBiologicalProcess	response to corticotropin-releasing hormone	CRHR1 CRHR2	1.89e-04	6	74	2	GO:0043435
GeneOntologyBiologicalProcess	negative regulation of feeding behavior	CEACAM8 CRHR1 CRHR2	2.24e-04	33	74	3	GO:2000252
GeneOntologyBiologicalProcess	organic hydroxy compound transport	ABCC3 COMT CEACAM8 AQP7P3 CRHR1 CRHR2 SLC27A5	2.97e-04	358	74	7	GO:0015850
GeneOntologyBiologicalProcess	monocarboxylic acid biosynthetic process	ACSM4 ACSM3 HTD2 CEACAM8 ACSM5 SLC27A5	3.43e-04	260	74	6	GO:0072330
GeneOntologyBiologicalProcess	regulation of cAMP-mediated signaling	GIPR CRHR1 CRHR2	3.98e-04	40	74	3	GO:0043949
GeneOntologyBiologicalProcess	L-fucose catabolic process	FUT4 FUT5	4.50e-04	9	74	2	GO:0042355
GeneOntologyBiologicalProcess	fucose catabolic process	FUT4 FUT5	4.50e-04	9	74	2	GO:0019317
GeneOntologyBiologicalProcess	modified amino acid transport	SLC22A16 SLC22A4 SLC22A5	5.28e-04	44	74	3	GO:0072337
GeneOntologyBiologicalProcess	L-fucose metabolic process	FUT4 FUT5	5.61e-04	10	74	2	GO:0042354
GeneOntologyBiologicalProcess	negative regulation of epinephrine secretion	CRHR1 CRHR2	5.61e-04	10	74	2	GO:0032811
GeneOntologyBiologicalProcess	negative regulation of behavior	CEACAM8 CRHR1 CRHR2	5.64e-04	45	74	3	GO:0048521
GeneOntologyBiologicalProcess	fatty acid biosynthetic process	ACSM4 ACSM3 HTD2 CEACAM8 ACSM5	6.21e-04	191	74	5	GO:0006633
GeneOntologyBiologicalProcess	acyl-CoA metabolic process	ACSM4 ACSM3 HTD2 ACSM5	6.39e-04	109	74	4	GO:0006637
GeneOntologyBiologicalProcess	thioester metabolic process	ACSM4 ACSM3 HTD2 ACSM5	6.39e-04	109	74	4	GO:0035383
GeneOntologyBiologicalProcess	bile acid and bile salt transport	ABCC3 CEACAM8 SLC27A5	6.42e-04	47	74	3	GO:0015721
GeneOntologyCellularComponent	basal plasma membrane	ABCC3 SLC22A4 SLC22A5 CEACAM8 AQP7P3 SLC4A4 CR1 SLC27A5	3.56e-05	354	74	8	GO:0009925
GeneOntologyCellularComponent	basal part of cell	ABCC3 SLC22A4 SLC22A5 CEACAM8 AQP7P3 SLC4A4 CR1 SLC27A5	5.65e-05	378	74	8	GO:0045178
Domain	AMP-bd_C	ACSM4 ACSM3 ACSM5 SLC27A5	4.65e-07	17	72	4	IPR025110
Domain	AMP-binding_C	ACSM4 ACSM3 ACSM5 SLC27A5	4.65e-07	17	72	4	PF13193
Domain	AMP-binding_CS	ACSM4 ACSM3 ACSM5 SLC27A5	2.85e-06	26	72	4	IPR020845
Domain	AMP_BINDING	ACSM4 ACSM3 ACSM5 SLC27A5	3.88e-06	28	72	4	PS00455
Domain	AMP-binding	ACSM4 ACSM3 ACSM5 SLC27A5	5.16e-06	30	72	4	PF00501
Domain	AMP-dep_Synth/Lig	ACSM4 ACSM3 ACSM5 SLC27A5	5.16e-06	30	72	4	IPR000873
Domain	GPCR_2_CRF_rcpt	CRHR1 CRHR2	4.39e-05	3	72	2	IPR003051
Domain	HormR	GIPR CRHR1 CRHR2	1.19e-04	25	72	3	SM00008
Domain	MFS_dom	SLC22A16 SLC22A4 SLC22A5 SLC16A11 MFSD13A	1.68e-04	134	72	5	IPR020846
Domain	HRM	GIPR CRHR1 CRHR2	1.68e-04	28	72	3	PF02793
Domain	GPCR_2_secretin-like_CS	GIPR CRHR1 CRHR2	3.02e-04	34	72	3	IPR017983
Domain	MFS_sugar_transport-like	SLC22A16 SLC22A4 SLC22A5	3.58e-04	36	72	3	IPR005828
Domain	Sugar_tr	SLC22A16 SLC22A4 SLC22A5	3.58e-04	36	72	3	PF00083
Domain	Glyco_transf_10	FUT4 FUT5	4.04e-04	8	72	2	PF00852
Domain	Glyco_tran_10_N	FUT4 FUT5	4.04e-04	8	72	2	PF17039
Domain	Glyco_trans_10	FUT4 FUT5	4.04e-04	8	72	2	IPR001503
Domain	Glyco_tran_10_N	FUT4 FUT5	4.04e-04	8	72	2	IPR031481
Domain	G_PROTEIN_RECEP_F2_1	GIPR CRHR1 CRHR2	4.90e-04	40	72	3	PS00649
Domain	GPCR_2_extracellular_dom	GIPR CRHR1 CRHR2	4.90e-04	40	72	3	IPR001879
Domain	G_PROTEIN_RECEP_F2_3	GIPR CRHR1 CRHR2	4.90e-04	40	72	3	PS50227
Domain	Orgcat_transp/SVOP	SLC22A4 SLC22A5	5.18e-04	9	72	2	IPR004749
Domain	MFS	SLC22A16 SLC22A4 SLC22A5 SLC16A11	8.04e-04	108	72	4	PS50850
Domain	G_PROTEIN_RECEP_F2_2	GIPR CRHR1 CRHR2	9.45e-04	50	72	3	PS00650
Domain	7tm_2	GIPR CRHR1 CRHR2	9.45e-04	50	72	3	PF00002
Domain	GPCR_2_secretin-like	GIPR CRHR1 CRHR2	1.61e-03	60	72	3	IPR000832
Domain	GPCR_2-like	GIPR CRHR1 CRHR2	1.61e-03	60	72	3	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	GIPR CRHR1 CRHR2	1.68e-03	61	72	3	PS50261
Domain	PWWP	PWWP2B ZCWPW2	3.52e-03	23	72	2	PF00855
Domain	PWWP_dom	PWWP2B ZCWPW2	3.52e-03	23	72	2	IPR000313
Domain	PWWP	PWWP2B ZCWPW2	3.83e-03	24	72	2	PS50812
Domain	SUGAR_TRANSPORT_1	SLC22A4 SLC22A5	3.83e-03	24	72	2	PS00216
Domain	Sugar_transporter_CS	SLC22A4 SLC22A5	6.75e-03	32	72	2	IPR005829
Pathway	REACTOME_ORGANIC_CATION_TRANSPORT	SLC22A16 SLC22A4 SLC22A5	2.94e-06	8	54	3	MM15191
Pathway	REACTOME_ORGANIC_CATION_TRANSPORT	SLC22A16 SLC22A4 SLC22A5	6.26e-06	10	54	3	M27450
Pathway	REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT	SLC22A16 SLC22A4 SLC22A5	1.14e-05	12	54	3	MM15192
Pathway	REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT	SLC22A16 SLC22A4 SLC22A5	2.34e-05	15	54	3	M888
Pathway	WP_GPCRS_CLASS_B_SECRETINLIKE	GIPR CRHR1 CRHR2	1.02e-04	24	54	3	M39643
Pathway	WP_GPCRS_CLASS_B_SECRETINLIKE	GIPR CRHR1 CRHR2	1.02e-04	24	54	3	MM15992
Pathway	KEGG_MEDICUS_REFERENCE_LEWIS_X_ANTIGEN_BIOSYNTHESIS	FUT4 FUT5	1.43e-04	5	54	2	M47966
Pathway	REACTOME_CONJUGATION_OF_SALICYLATE_WITH_GLYCINE	ACSM4 ACSM5	2.14e-04	6	54	2	MM14693
Pathway	KEGG_MEDICUS_REFERENCE_SIALYL_LEWIS_X_ANTIGEN_BIOSYNTHESIS	FUT4 FUT5	2.14e-04	6	54	2	M47967
Pathway	KEGG_BUTANOATE_METABOLISM	ACSM4 ACSM3 ACSM5	2.92e-04	34	54	3	M3397
Pathway	REACTOME_AMINO_ACID_CONJUGATION	ACSM4 ACSM5	2.99e-04	7	54	2	MM14598
Pathway	REACTOME_AMINO_ACID_CONJUGATION	ACSM4 ACSM5	5.10e-04	9	54	2	M26968
Pathway	WP_GPCRS_NONODORANT	GIPR NPBWR1 TAS2R41 ACKR1 CRHR1 CRHR2	5.16e-04	266	54	6	MM15843
Pathway	REACTOME_ASPIRIN_ADME	ABCC3 ACSM4 ACSM5	6.30e-04	44	54	3	M45014
Pathway	REACTOME_ASPIRIN_ADME	ABCC3 ACSM4 ACSM5	6.73e-04	45	54	3	MM15694
Pathway	BIOCARTA_AMAN_PATHWAY	FUT4 FUT5	1.46e-03	15	54	2	M22009
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	GIPR CRHR1 CRHR2	1.56e-03	60	54	3	MM14964
Pubmed	STRC-Related Autosomal Recessive Hearing Loss	CATSPER2 STRC	4.84e-06	2	77	2	38109326
Pubmed	Haplotype in the IBD5 region is associated with refractory Crohn's disease in Slovenian patients and modulates expression of the SLC22A5 gene.	SLC22A4 SLC22A5	4.84e-06	2	77	2	21695374
Pubmed	Molecular and functional characterization of organic cation/carnitine transporter family in mice.	SLC22A4 SLC22A5	4.84e-06	2	77	2	11010964
Pubmed	Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth indices in early onset inflammatory bowel disease.	SLC22A4 SLC22A5	4.84e-06	2	77	2	16469794
Pubmed	Expression and subcellular localization of CRH and its receptors in human endometrial cancer.	CRHR1 CRHR2	4.84e-06	2	77	2	19433256
Pubmed	Molecular mechanisms of corticotropin-releasing factor receptor-induced calcium signaling.	CRHR1 CRHR2	4.84e-06	2	77	2	19098121
Pubmed	Gene expression of carnitine organic cation transporters 1 and 2 (OCTN) is downregulated in patients with ulcerative colitis.	SLC22A4 SLC22A5	4.84e-06	2	77	2	21910182
Pubmed	Association of SLC22A4/5 polymorphisms with steroid responsiveness of inflammatory bowel disease in Japan.	SLC22A4 SLC22A5	4.84e-06	2	77	2	18274826
Pubmed	Corticotropin-releasing factor receptors induce calcium mobilization through cross-talk with Gq-coupled receptors.	CRHR1 CRHR2	4.84e-06	2	77	2	20594969
Pubmed	Novel corticotropin-releasing hormone receptor genes (CRHR1 and CRHR2) linkage to and association with polycystic ovary syndrome.	CRHR1 CRHR2	4.84e-06	2	77	2	37543650
Pubmed	Association of CRHR1 and CRHR2 with major depressive disorder and panic disorder in a Japanese population.	CRHR1 CRHR2	4.84e-06	2	77	2	22467522
Pubmed	Expression patterns of the organic cation/carnitine transporter family in adult murine brain.	SLC22A4 SLC22A5	4.84e-06	2	77	2	17576045
Pubmed	Substrate discrimination by ergothioneine transporter SLC22A4 and carnitine transporter SLC22A5: gain-of-function by interchange of selected amino acids.	SLC22A4 SLC22A5	4.84e-06	2	77	2	19814996
Pubmed	Functional genetic variation in the basal promoter of the organic cation/carnitine transporters OCTN1 (SLC22A4) and OCTN2 (SLC22A5).	SLC22A4 SLC22A5	4.84e-06	2	77	2	19141711
Pubmed	Contribution of the IBD5 locus to Crohn's disease in the Swedish population.	SLC22A4 SLC22A5	4.84e-06	2	77	2	17340776
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	4.84e-06	2	77	2	11687802
Pubmed	Prevalence of SLC22A4 1672T and SLC22A5 -207C combination defined TC haplotype in Hungarian ulcerative colitis patients.	SLC22A4 SLC22A5	4.84e-06	2	77	2	17387389
Pubmed	Dysregulation of bladder corticotropin-releasing hormone receptor in the pathogenesis of human interstitial cystitis/bladder pain syndrome.	CRHR1 CRHR2	4.84e-06	2	77	2	31844086
Pubmed	Corticotropin-releasing hormone receptor (CRHR)1 and CRHR2 are both trafficking and signaling receptors for urocortin.	CRHR1 CRHR2	4.84e-06	2	77	2	17170072
Pubmed	Tooth loss and adiposity: possible role of carnitine transporter (OCTN1/2) polymorphisms in women but not in men.	SLC22A4 SLC22A5	4.84e-06	2	77	2	32964310
Pubmed	Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons.	SLC22A4 SLC22A5	4.84e-06	2	77	2	21606177
Pubmed	Genetic variation in the corticotrophin-releasing factor receptors: identification of single-nucleotide polymorphisms and association studies with obesity in UK Caucasians.	CRHR1 CRHR2	4.84e-06	2	77	2	14724656
Pubmed	Direct or indirect association in a complex disease: the role of SLC22A4 and SLC22A5 functional variants in Crohn disease.	SLC22A4 SLC22A5	4.84e-06	2	77	2	16835882
Pubmed	Transport of ipratropium, an anti-chronic obstructive pulmonary disease drug, is mediated by organic cation/carnitine transporters in human bronchial epithelial cells: implications for carrier-mediated pulmonary absorption.	SLC22A4 SLC22A5	4.84e-06	2	77	2	20020740
Pubmed	Expression of corticotropin-releasing hormone receptor type 1 and type 2 in human pregnant myometrium.	CRHR1 CRHR2	4.84e-06	2	77	2	17959885
Pubmed	Differential regulation of prostaglandin production mediated by corticotropin-releasing hormone receptor type 1 and type 2 in cultured human placental trophoblasts.	CRHR1 CRHR2	4.84e-06	2	77	2	18325997
Pubmed	Association study between the corticotropin-releasing hormone receptor 2 gene and suicidality in bipolar disorder.	CRHR1 CRHR2	4.84e-06	2	77	2	17532191
Pubmed	The highly selective CRF(2) receptor antagonist K41498 binds to presynaptic CRF(2) receptors in rat brain.	CRHR1 CRHR2	4.84e-06	2	77	2	12110614
Pubmed	HPA axis genes may modulate the effect of childhood adversities on decision-making in suicide attempters.	CRHR1 CRHR2	4.84e-06	2	77	2	23177644
Pubmed	[Possible role of selected IGR and SLC22A4/SLC22A5 loci in development of inflammatory bowel diseases].	SLC22A4 SLC22A5	4.84e-06	2	77	2	19581171
Pubmed	Different effects of chronic social defeat on social behavior and the brain CRF system in adult male C57 mice with different susceptibilities.	CRHR1 CRHR2	4.84e-06	2	77	2	32057826
Pubmed	Polymorphisms in the organic cation transporter genes SLC22A4 and SLC22A5 and Crohn's disease in a New Zealand Caucasian cohort.	SLC22A4 SLC22A5	4.84e-06	2	77	2	16519742
Pubmed	Distinct distribution of corticotropin releasing factor receptors in human breast cancer.	CRHR1 CRHR2	4.84e-06	2	77	2	20630588
Pubmed	Frequency of the STRC-CATSPER2 deletion in STRC-associated hearing loss patients.	CATSPER2 STRC	4.84e-06	2	77	2	35022556
Pubmed	Functional activity of L-carnitine transporters in human airway epithelial cells.	SLC22A4 SLC22A5	4.84e-06	2	77	2	26607009
Pubmed	OCTNs: will the real IBD5 gene please stand up?	SLC22A4 SLC22A5	4.84e-06	2	77	2	16773684
Pubmed	Effect of CRHR1 and CRHR2 gene polymorphisms and childhood trauma in suicide attempt.	CRHR1 CRHR2	4.84e-06	2	77	2	30874897
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	4.84e-06	2	77	2	34910522
Pubmed	Expression and functional characterization of membrane-integrated mammalian corticotropin releasing factor receptors 1 and 2 in Escherichia coli.	CRHR1 CRHR2	4.84e-06	2	77	2	24465390
Pubmed	Association of the organic cation transporter OCTN genes with Crohn's disease in the Spanish population.	SLC22A4 SLC22A5	4.84e-06	2	77	2	16333318
Pubmed	Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients.	SLC22A4 SLC22A5	4.84e-06	2	77	2	21793125
Pubmed	Organic cation/carnitine transporter family expression patterns in adult murine heart.	SLC22A4 SLC22A5	4.84e-06	2	77	2	19233567
Pubmed	Expression and localization of carnitine/organic cation transporter OCTN1 and OCTN2 in ocular epithelium.	SLC22A4 SLC22A5	4.84e-06	2	77	2	18641280
Pubmed	SLC22A4 and SLC22A5 gene polymorphisms and Crohn's disease in the Chinese Han population.	SLC22A4 SLC22A5	4.84e-06	2	77	2	19659785
Pubmed	Characterization of organic cation/carnitine transporter family in human sperm.	SLC22A4 SLC22A5	4.84e-06	2	77	2	12788076
Pubmed	Association between OCTN1/2 gene polymorphisms (1672C-T, 207G-C) and susceptibility of Crohn's disease: a meta-analysis.	SLC22A4 SLC22A5	4.84e-06	2	77	2	21706137
Pubmed	Evidence for association of OCTN genes and IBD5 with ulcerative colitis.	SLC22A4 SLC22A5	4.84e-06	2	77	2	16361305
Pubmed	Evidence for the association of the SLC22A4 and SLC22A5 genes with type 1 diabetes: a case control study.	SLC22A4 SLC22A5	4.84e-06	2	77	2	16796743
Pubmed	Association between corticotropin-releasing hormone receptor 1 and 2 (CRHR1 and CRHR2) gene polymorphisms and personality traits.	CRHR1 CRHR2	4.84e-06	2	77	2	23982282
Pubmed	Ethanol concentration-dependent effects and the role of stress on ethanol drinking in corticotropin-releasing factor type 1 and double type 1 and 2 receptor knockout mice.	CRHR1 CRHR2	4.84e-06	2	77	2	21487655
Pubmed	Corticotropin-Releasing Hormone Family and Their Receptors in the Cardiovascular System.	CRHR1 CRHR2	4.84e-06	2	77	2	30584229
Pubmed	Expression and functional analysis of intestinal organic cation/L-carnitine transporter (OCTN) in Crohn's disease.	SLC22A4 SLC22A5	4.84e-06	2	77	2	22325173
Pubmed	Corticotropin-releasing hormone receptor expression on normal and tumorous human adrenocortical cells.	CRHR1 CRHR2	4.84e-06	2	77	2	16721033
Pubmed	Estrogen alters the splicing of type 1 corticotropin-releasing hormone receptor in breast cancer cells.	CRHR1 CRHR2	4.84e-06	2	77	2	23821771
Pubmed	Polymorphisms in OCTN1 and OCTN2 transporters genes are associated with prolonged time to progression in unresectable gastrointestinal stromal tumours treated with imatinib therapy.	SLC22A4 SLC22A5	4.84e-06	2	77	2	23127916
Pubmed	LPS-induced inflammation delays the transportation of ASP+ due to down-regulation of OCTN1/2 in alveolar epithelial cells.	SLC22A4 SLC22A5	4.84e-06	2	77	2	31591905
Pubmed	Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.	ABCC3 SLC22A4 SLC22A5	5.72e-06	16	77	3	35307651
Pubmed	Corticotropin-releasing hormone family of peptides regulates intestinal angiogenesis.	CRHR1 CRHR2	1.45e-05	3	77	2	20206175
Pubmed	Corticotropin-releasing hormone receptor type 1 and type 2 mediate differential effects on 15-hydroxy prostaglandin dehydrogenase expression in cultured human chorion trophoblasts.	CRHR1 CRHR2	1.45e-05	3	77	2	17463062
Pubmed	Monoclonal antibodies that recognize lacto-N-fucopentaose III (CD15) react with the adhesion-promoting glycoprotein family (LFA-1/HMac-1/gp 150,95) and CR1 on human neutrophils.	FUT4 CR1	1.45e-05	3	77	2	3305706
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	1.45e-05	3	77	2	30801007
Pubmed	Corticotropin releasing hormone receptor alterations elicited by acute and chronic unpredictable stressor challenges in stressor-susceptible and resilient strains of mice.	CRHR1 CRHR2	1.45e-05	3	77	2	17517441
Pubmed	Corticotropin-releasing hormone receptor-1 in cerebral microvessels changes during development and influences urocortin transport across the blood-brain barrier.	CRHR1 CRHR2	1.45e-05	3	77	2	20032050
Pubmed	Screening genes associated with elevated neutrophil‑to‑lymphocyte ratio in chronic heart failure.	IL1R2 SLC22A4	1.45e-05	3	77	2	29901123
Pubmed	The CRF1 and the CRF2 receptor mediate recognition memory deficits and vulnerability induced by opiate withdrawal.	CRHR1 CRHR2	1.45e-05	3	77	2	26907806
Pubmed	CRF1 and CRF2 receptors are required for potentiated startle to contextual but not discrete cues.	CRHR1 CRHR2	1.45e-05	3	77	2	19020499
Pubmed	Corticotropin-releasing factor receptors CRF1 and CRF2 exert both additive and opposing influences on defensive startle behavior.	CRHR1 CRHR2	1.45e-05	3	77	2	15269266
Pubmed	Reduced cerebral injury in CRH-R1 deficient mice after focal ischemia: a potential link to microglia and atrocytes that express CRH-R1.	CRHR1 CRHR2	1.45e-05	3	77	2	14526225
Pubmed	A risk haplotype in the Solute Carrier Family 22A4/22A5 gene cluster influences phenotypic expression of Crohn's disease.	SLC22A4 SLC22A5	1.45e-05	3	77	2	15685536
Pubmed	Physical maps of human alpha (1,3)fucosyltransferase genes FUT3-FUT6 on chromosomes 19p13.3 and 11q21.	FUT4 FUT5	1.45e-05	3	77	2	7782074
Pubmed	Functional variants of OCTN cation transporter genes are associated with Crohn disease.	SLC22A4 SLC22A5	1.45e-05	3	77	2	15107849
Pubmed	Regulation of the hypothalamic-pituitary-adrenocortical system in mice deficient for CRH receptors 1 and 2.	CRHR1 CRHR2	1.45e-05	3	77	2	11606463
Pubmed	Consolidation of remote fear memories involves Corticotropin-Releasing Hormone (CRH) receptor type 1-mediated enhancement of AMPA receptor GluR1 signaling in the dentate gyrus.	CRHR1 CRHR2	1.45e-05	3	77	2	22030710
Pubmed	Contribution of OCTN variants within the IBD5 locus to pediatric onset Crohn's disease.	SLC22A4 SLC22A5	1.45e-05	3	77	2	16771961
Pubmed	DNA methylation of HPA-axis genes and the onset of major depressive disorder in adolescent girls: a prospective analysis.	CRHR1 CRHR2	1.45e-05	3	77	2	31582756
Pubmed	The role of hypothalamus-pituitary-adrenal genes and childhood trauma in borderline personality disorder.	CRHR1 CRHR2	1.45e-05	3	77	2	26182893
Pubmed	Polymorphisms in the IBD5 locus are associated with Crohn disease in pediatric Ashkenazi Jewish patients.	SLC22A4 SLC22A5	1.45e-05	3	77	2	19412005
Pubmed	Replication of TPMT and ABCC3 genetic variants highly associated with cisplatin-induced hearing loss in children.	ABCC3 COMT	1.45e-05	3	77	2	23588304
Pubmed	Corticotropin-releasing hormone receptor-1 and 2 activity produces divergent resistance against stress-induced pulmonary Streptococcus pneumoniae infection.	CRHR1 CRHR2	1.45e-05	3	77	2	21774994
Pubmed	Evidence for common genetic control in pathways of inflammation for Crohn's disease and psoriatic arthritis.	SLC22A4 SLC22A5	1.45e-05	3	77	2	16255050
Pubmed	Lipopolysaccharide-induced tau phosphorylation and kinase activity--modulation, but not mediation, by corticotropin-releasing factor receptors.	CRHR1 CRHR2	1.45e-05	3	77	2	21722209
Pubmed	The effects of repeated restraint stress on energy balance and behavior of mice with selective deletion of CRF receptors.	CRHR1 CRHR2	1.45e-05	3	77	2	20392192
Pubmed	Suppression of the MEK/ERK signaling pathway reverses depression-like behaviors of CRF2-deficient mice.	CRHR1 CRHR2	1.45e-05	3	77	2	18843268
Pubmed	Expression of the organic cation/carnitine transporter family (Octn1,-2 and-3) in mdx muscle and heart: Implications for early carnitine therapy in Duchenne muscular dystrophy to improve cellular carnitine homeostasis.	SLC22A4 SLC22A5	1.45e-05	3	77	2	32070725
Pubmed	Mice deficient for both corticotropin-releasing factor receptor 1 (CRFR1) and CRFR2 have an impaired stress response and display sexually dichotomous anxiety-like behavior.	CRHR1 CRHR2	1.45e-05	3	77	2	11756502
Pubmed	Specificity and regulation of extracellularly regulated kinase1/2 phosphorylation through corticotropin-releasing factor (CRF) receptors 1 and 2beta by the CRF/urocortin family of peptides.	CRHR1 CRHR2	1.45e-05	3	77	2	14670995
Pubmed	Variants of OCTN1-2 cation transporter genes are associated with both Crohn's disease and ulcerative colitis.	SLC22A4 SLC22A5	1.45e-05	3	77	2	16441470
Pubmed	Inhibition of corticotropin-releasing hormone receptor 1 and activation of receptor 2 protect against colonic injury and promote epithelium repair.	CRHR1 CRHR2	1.45e-05	3	77	2	28492284
Pubmed	IGR2096a_1 T and IGR2198a_1 C alleles on IBD5 locus of chromosome 5q31 region confer risk for Crohn's disease in Hungarian patients.	SLC22A4 SLC22A5	1.45e-05	3	77	2	19214536
Pubmed	The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease.	SLC22A4 SLC22A5	1.45e-05	3	77	2	16344054
Pubmed	Distribution of corticotropin-releasing factor (CRF) receptor binding in the mouse brain using a new, high-affinity radioligand, [125 I]-PD-Sauvagine.	CRHR1 CRHR2	1.45e-05	3	77	2	28842924
Pubmed	OCTN and CARD15 gene polymorphism in Chinese patients with inflammatory bowel disease.	SLC22A4 SLC22A5	1.45e-05	3	77	2	18756601
Pubmed	Identification of a novel murine receptor for corticotropin-releasing hormone expressed in the heart.	CRHR1 CRHR2	1.45e-05	3	77	2	7565810
Pubmed	Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities.	FUT4 FUT5	1.45e-05	3	77	2	1740457
Pubmed	Role of SLC22A4, SLC22A5, and RUNX1 genes in rheumatoid arthritis.	SLC22A4 SLC22A5	1.45e-05	3	77	2	16652416
Pubmed	Stress-induced differences in primary and secondary resistance against bacterial sepsis corresponds with diverse corticotropin releasing hormone receptor expression by pulmonary CD11c+ MHC II+ and CD11c- MHC II+ APCs.	CRHR1 CRHR2	1.45e-05	3	77	2	18166336
Pubmed	Corticotropin-releasing factor, urocortin 1, and their receptors in the mouse spinal cord.	CRHR1 CRHR2	1.45e-05	3	77	2	17444496
Pubmed	Animal models of CRH excess and CRH receptor deficiency display altered adaptations to stress.	CRHR1 CRHR2	1.45e-05	3	77	2	11337086
Pubmed	Plasma Corticotropin-Releasing Factor Receptors and B7-2⁺ Extracellular Vesicles in Blood Correlate with Irritable Bowel Syndrome Disease Severity.	CRHR1 CRHR2	1.45e-05	3	77	2	30704133
Pubmed	Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease.	SLC22A4 SLC22A5	1.45e-05	3	77	2	15955786
Cytoband	15q15.3	CATSPER2 STRC STRCP1	1.02e-05	25	77	3	15q15.3
Cytoband	14q11.2	OR11G2 TM9SF1 OR11H12 OR11H2	2.47e-04	180	77	4	14q11.2
Cytoband	Xq22	COL4A6 NXF5	6.28e-04	22	77	2	Xq22
Cytoband	Ensembl 112 genes in cytogenetic band chr15q15	CATSPER2 STRC STRCP1	1.98e-03	147	77	3	chr15q15
GeneFamily	Olfactory receptors, family 11	OR11G2 OR11H1 OR11H12 OR11H2	8.07e-07	23	58	4	159
GeneFamily	Acyl-CoA synthetase family	ACSM4 ACSM3 ACSM5 SLC27A5	1.35e-06	26	58	4	40
GeneFamily	Corticotropin releasing hormone receptors	CRHR1 CRHR2	1.01e-05	2	58	2	266
GeneFamily	Solute carriers	SLC22A16 SLC22A4 SLC22A5 SLC25A14 SLC16A11 SLC4A4 SLC27A5	2.59e-04	395	58	7	752
GeneFamily	Fucosyltransferases\|Blood group antigens	FUT4 FUT5	7.71e-04	13	58	2	434
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	IL1R2 CEACAM8 FUT4 CR1 ACKR1 FCAMR	1.60e-03	394	58	6	471
GeneFamily	PWWP domain containing	PWWP2B ZCWPW2	2.24e-03	22	58	2	1147
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	CR1 ACKR1	6.27e-03	37	58	2	454
Coexpression	GSE6269_E_COLI_VS_STREP_PNEUMO_INF_PBMC_DN	IL1R2 TM9SF1 CEACAM8 SDF4 FUT4 CR1	9.56e-06	168	76	6	M5662
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Cacng4_(Non-anterior_nuclei)\|Thalamus / BrainAtlas - Mouse McCarroll V32	XYLT2 GPR88 DCST1 ATP2A1	9.26e-06	76	77	4	4afc8d0e79870c635a89dd8e7ca91ebfe482b4ab
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A4 PRSS56 KIRREL2 SLC4A4 TMEM89	1.06e-05	167	77	5	2184c2760b6142e62124a2454a552723e20d4f61
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM130 SLC16A11 ACKR1 FCAMR CRHR2	1.32e-05	175	77	5	19eda8b5d39dc93d79737ebdbeeba5ec0cb23c51
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Pvalb_(Non-anterior_nuclei)\|Thalamus / BrainAtlas - Mouse McCarroll V32	XYLT2 GPR88 DCST1 ATP2A1	1.58e-05	87	77	4	fd0df79b02f96463a6bad90dcd019c59c8e3eb0e
ToppCell	Frontal_cortex-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Gja1)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PRSS56 ACSM5 KIRREL2 TMEM89	2.43e-05	97	77	4	031bc124739541b0b2591e1b6ef41f12adfd5c18
ToppCell	Frontal_cortex-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Gja1)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PRSS56 ACSM5 KIRREL2 TMEM89	2.43e-05	97	77	4	0cd19f619f10a35d3107518aa83c0eda0572930a
ToppCell	Frontal_cortex-Macroglia-ASTROCYTE-Gja1-Gfap-_astrocytes_(Gja1)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PRSS56 ACSM5 KIRREL2 TMEM89	2.43e-05	97	77	4	33330ac2de9e49d78b478f175068999235c9af25
Drug	phenylalanyl corticotropin-releasing factor (12-41)	CRHR1 CRHR2	1.04e-05	2	74	2	ctd:C113202
Drug	1-(3-pyridyl)-1-butanone	ABCC3 SLC4A4 CRHR1 CRHR2	1.05e-05	42	74	4	CID000459502
Drug	O-methylisoprenaline	COMT SLC22A4 SLC22A5	1.46e-05	15	74	3	CID000068951
Drug	Tetraethylammonium	SLC22A16 SLC22A4 SLC22A5	1.79e-05	16	74	3	ctd:D019789
Disease	dihomo-linolenoylcarnitine (C20:3n3 or 6) measurement	SLC22A16 SLC22A4 SLC22A5	3.75e-06	13	71	3	EFO_0800547
Disease	cerotoylcarnitine (C26) measurement	SLC22A16 SLC22A4 SLC22A5	3.75e-06	13	71	3	EFO_0800542
Disease	Deafness-infertility syndrome	CATSPER2 STRC	5.71e-06	2	71	2	cv:C1970187
Disease	Deafness, Sensorineural, And Male Infertility	CATSPER2 STRC	5.71e-06	2	71	2	C1970187
Disease	DEAFNESS-INFERTILITY SYNDROME	CATSPER2 STRC	5.71e-06	2	71	2	611102
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	5.71e-06	2	71	2	DOID:0110471 (implicated_via_orthology)
Disease	margaroylcarnitine (C17) measurement	SLC22A16 SLC22A5	5.71e-06	2	71	2	EFO_0800345
Disease	docosapentaenoylcarnitine (C22:5n3) measurement	SLC22A16 SLC22A5	5.71e-06	2	71	2	EFO_0800550
Disease	oleoylcarnitine measurement	SLC22A16 SLC22A4 SLC22A5	1.26e-05	19	71	3	EFO_0021043
Disease	Spermatogenic Failure 7	CATSPER2 STRC	1.71e-05	3	71	2	C2751811
Disease	palmitoleoylcarnitine (C16:1) measurement	SLC22A16 SLC22A4	1.71e-05	3	71	2	EFO_0800493
Disease	Spermatogenic failure 7	CATSPER2 STRC	1.71e-05	3	71	2	cv:C2751811
Disease	functional colonic disease (biomarker_via_orthology)	CRHR1 CRHR2	1.71e-05	3	71	2	DOID:3877 (biomarker_via_orthology)
Disease	SPERMATOGENIC FAILURE 7	CATSPER2 STRC	1.71e-05	3	71	2	612997
Disease	linolenoylcarnitine (C18:3) measurement	SLC22A16 SLC22A5	1.71e-05	3	71	2	EFO_0800538
Disease	stearoylcarnitine measurement	SLC22A16 SLC22A4 SLC22A5	2.61e-05	24	71	3	EFO_0021045
Disease	Anhedonia	COMT CRHR1 CRHR2	2.61e-05	24	71	3	C0178417
Disease	myristoylcarnitine (C14) measurement	SLC22A16 SLC22A4	3.41e-05	4	71	2	EFO_0800216
Disease	linoleoylcarnitine (C18:2) measurement	SLC22A16 SLC22A5	5.68e-05	5	71	2	EFO_0800338
Disease	Coxsackievirus Infections	SLC22A4 SLC22A5	8.51e-05	6	71	2	C0010246
Disease	Myocarditis	SLC22A4 SLC22A5	8.51e-05	6	71	2	C0027059
Disease	Carditis	SLC22A4 SLC22A5	8.51e-05	6	71	2	C0869523
Disease	Dysphoric mood	COMT CRHR2	1.19e-04	7	71	2	C0233477
Disease	acetylcarnitine measurement	SLC22A4 SLC22A5	1.58e-04	8	71	2	EFO_0021038
Disease	irritable bowel syndrome (biomarker_via_orthology)	CRHR1 CRHR2	1.58e-04	8	71	2	DOID:9778 (biomarker_via_orthology)
Disease	X-17676 measurement	ACSM3 ACSM5	1.58e-04	8	71	2	EFO_0800785
Disease	butyrylcarnitine measurement	SLC22A4 SLC22A5	1.58e-04	8	71	2	EFO_0020010
Disease	nervonoylcarnitine (C24:1) measurement	SLC22A4 SLC22A5	2.03e-04	9	71	2	EFO_0800549
Disease	lignoceroylcarnitine (C24) measurement	SLC22A4 SLC22A5	3.10e-04	11	71	2	EFO_0800541
Disease	tryptophan betaine measurement	SLC22A4 SLC22A5	3.71e-04	12	71	2	EFO_0021017
Disease	hexanoylcarnitine measurement	SLC22A4 SLC22A5	3.71e-04	12	71	2	EFO_0021040
Disease	arachidonoylcarnitine (C20:4) measurement	SLC22A16 SLC22A4	3.71e-04	12	71	2	EFO_0800544
Disease	X-12707 measurement	ARSL COMT	3.71e-04	12	71	2	EFO_0800720
Disease	homostachydrine measurement	SLC22A4 SLC22A5	4.38e-04	13	71	2	EFO_0021164
Disease	ximenoylcarnitine (C26:1) measurement	SLC22A16 SLC22A5	4.38e-04	13	71	2	EFO_0800543
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	GIPR TDRD15 SLC22A4 SLC22A5	4.78e-04	150	71	4	EFO_0004611, EFO_0020947
Disease	cholangiocarcinoma (is_marker_for)	IL1R2 PRSS56 SLC4A4	5.01e-04	64	71	3	DOID:4947 (is_marker_for)
Disease	–	CR1 ACKR1	6.70e-04	16	71	2	611162
Disease	Malaria, susceptibility to	CR1 ACKR1	6.70e-04	16	71	2	cv:C1970028
Disease	carnitine measurement	SLC22A16 SLC22A4 SLC22A5	8.27e-04	76	71	3	EFO_0010469
Disease	Anorexia	CRHR1 CRHR2	8.52e-04	18	71	2	C0003123
Disease	Malaria	CR1 ACKR1	1.05e-03	20	71	2	C0024530
Disease	palmitoylcarnitine measurement	SLC22A16 SLC22A5	1.16e-03	21	71	2	EFO_0021044
Disease	obesity (is_implicated_in)	GIPR COMT CRHR1	1.39e-03	91	71	3	DOID:9970 (is_implicated_in)
Disease	malaria (is_implicated_in)	CR1 ACKR1	1.52e-03	24	71	2	DOID:12365 (is_implicated_in)
Disease	ergothioneine measurement	SLC22A16 SLC22A4	1.79e-03	26	71	2	EFO_0021163
Disease	asthma, cardiovascular disease	SLC22A4 SLC22A5	2.38e-03	30	71	2	EFO_0000319, MONDO_0004979

Protein segments in the cluster

Peptide	Gene	Start	Entry
EQVLWGLPCSWVQVP	CARD10	976	Q9BWT7
TIPQCPLGWRSLWIG	COL4A6	1586	Q14031
RWGPLIGLAPCCLWL	SDF4	11	Q9BRK5
RLGNIWRPWLQPCCG	ARSL	561	P51690
CSQRPPLSLWAGWVL	CATSPER2	91	Q96P56
APSCRWRIPWQGLLL	CEACAM8	6	P31997
PLFRWQLCPGWPVLA	ACKR1	86	Q16570
VLPRLPEWWLVSVAC	ACSM5	121	Q6NUN0
LLGWGAPALFVIPWV	GIPR	261	P48546
LPRIPEWWLVNVACI	ACSM4	121	P0C7M7
LLSSPCWRLPGVYWQ	ANXA2R	56	Q3ZCQ2
PPWVNIWLLGSICLS	ATP2A1	926	O14983
KPRQAWVWAAVRGPC	ADAMTS13	681	Q76LX8
LLAWVPCIYLWVALP	ABCC3	36	O15438
ILCWVCGFLWFLIPI	OR11H2	161	Q8NH07
VCGWLADQGWVPLPR	SLC16A11	296	Q8NCK7
LPVPWGVQAASWLLC	GPR88	311	Q9GZN0
LPFILRPTSCWQLDW	M1AP	326	Q8TC57
LITYACWGQLPPLPW	FUT4	166	P22083
ENLWWVPVVAPLLGA	AQP7P3	251	A6NL99
AWVRPPCPVWASRLQ	LINC02693	41	A8MQB3
ACVWQLAYPPVWPNL	LBHD1	56	Q9BQE6
WDIWQPSGPQKVLIC	DYNC2I1	681	Q8WVS4
WWGGLRRTVCLNLPV	HTD2	11	P86397
FLPRAGPESQRWWCL	NXF5	351	Q9H1B4
GWCIPFPIIVAWAIG	CRHR2	231	Q13324
VEIGVFPLICGWWLD	MARCHF6	381	O60337
WAVWYQQPRGVALPC	KREMEN2	416	Q8NCW0
ALICLLWQVPRPPTW	PLD4	46	Q96BZ4
WGLCLIGWNEFILQP	COMT	31	P21964
YWCRLGPPRWICQTI	FCAMR	96	Q8WWV6
LPVAWGQCNAPEWLP	CR1	36	P17927
WFLWRQPGEFPVTAL	DCST1	36	Q5T197
CPQIQKLWSIGRWVP	C19orf67	276	A6NJJ6
ICIGWGVPFPIIVAW	CRHR1	261	P34998
GWRPLQSIPQLKWCL	DNAJC13	1016	O75165
GRPWALLWVLLCVQG	HAS1	426	Q92839
LWPWGACLPVIFLSL	INSRR	6	P14616
FSCAWRGNPLPRVTW	KIRREL2	331	Q6UWL6
IWIGKIWELQVPCSP	DNAH2	3336	Q9P225
FPWWPARVLDISLGQ	PWWP2B	501	Q6NUJ5
LALTVPGVLCVPLWW	SLC22A4	261	Q9H015
PGVLCVALWWFIPES	SLC22A5	266	O76082
FWVPWAPAGLQFLLC	MFSD13A	116	Q14CX5
PCRVWWRAPVVPATC	MFSD14C	131	Q5VZR4
WPWLVRLQLGGQPLC	PRSS56	116	P0CW18
RQCVLVFPQPEAFWW	NPBWR1	186	P48145
CWVLGFIWFLIPIVN	OR11G2	186	Q8NGC1
ILCWVCGFLWFLIPI	OR11H1	161	Q8NG94
ILCWVCGFLWFLIPI	OR11H12	161	B2RN74
PAKPQWLWRRCLAGL	FUT5	6	Q11128
WPWQIAVYLCISVHP	TAS2R41	266	P59536
IVLQRWWCQMEPCLP	TAFA3	91	Q7Z5A8
WRLGCLIWEVFNGPL	SCYL1	206	Q96KG9
RNIPRQAVPCKWIWF	TDRD15	1631	B5MCY1
FILCCWVLPETPFWL	SLC22A16	281	Q86VW1
FPPWLETWLQCRKQL	STEAP2	291	Q8NFT2
VALRCPQVPYWLWAS	IL1R2	46	P27930
VLVPFWPWLAGQCRI	STRC	546	Q7RTU9
PLLRQWVAICLGRIW	RPTOR	571	Q8N122
ILPRVPEWWLANVAC	ACSM3	126	Q53FZ2
PNWLRLGPWNIIFFI	SLC25A14	301	O95258
LWRCCQRVVGWVPVL	ZDHHC20	6	Q5W0Z9
ICPAPWGLRLWEKLT	MTRFR	16	Q9H3J6
LPVLRQPRAWGVLWC	PKMYT1	356	Q99640
LLWGLGQPVWPVAVA	SLC27A5	16	Q9Y2P5
PLWYQVGLDLQPWGC	TMEM89	26	A2RUT3
RILWLACLLPWAPAG	TMEM130	11	Q8N3G9
NPWWVCLAAAIPALL	SLC4A4	776	Q9Y6R1
VLVPFWPWLAGQCRI	STRCP1	546	A6NGW2
IFWLGLIACPVLWVI	TVP23B	126	Q9NYZ1
LQNWPSWPGILCPDR	ZCWPW2	106	Q504Y3
LIPVPWLQWLFGALA	YIPF2	221	Q9BWQ6
GLQSPPVWCDWQTLR	ZFYVE26	1526	Q68DK2
KYCIGVPPIQWLAWI	TRRAP	3221	Q9Y4A5
PWTVRLLQFWEPLGE	XYLT2	726	Q9H1B5
NPRSWSCQWLPILIL	TM9SF1	6	O15321
CPNPLFVRWLTEWRD	MUS81	16	Q96NY9