Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein serine kinase activity	CDK18 MAK PAK4 MAP3K20 PAK6 TESK1 TAOK2 PASK STK11 MAPK14 MAPK12 TAOK1 PRKDC MAPK1 MAPK11 MAP4K4	1.15e-08	363	147	16	GO:0106310
GeneOntologyMolecularFunction	protein kinase activity	CDK18 MAK MYLK PAK4 MAP3K20 PAK6 TESK1 TAOK2 PASK STK11 MAPK14 MAPK12 KDR TAOK1 PRKDC MAPK1 MAPK11 MAP4K4 HCK EPHA3	1.77e-08	600	147	20	GO:0004672
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	CDK18 MAK MYLK PAK4 MAP3K20 PAK6 TESK1 TAOK2 PASK STK11 MAPK14 MAPK12 TAOK1 PRKDC MAPK1 MAPK11 MAP4K4	3.32e-08	446	147	17	GO:0004674
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CDK18 MAK MYLK PAK4 MAP3K20 PAK6 TESK1 TAOK2 PASK STK11 MAPK14 MAPK12 KDR TAOK1 PRKDC MAPK1 MAPK11 MAP4K4 HCK EPHA3	2.66e-07	709	147	20	GO:0016773
GeneOntologyMolecularFunction	kinase activity	CDK18 MAK MYLK PAK4 MAP3K20 PAK6 TESK1 TAOK2 PASK STK11 MAPK14 MAPK12 KDR TAOK1 PRKDC MAPK1 MAPK11 MAP4K4 HCK EPHA3	8.59e-07	764	147	20	GO:0016301
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	CDK18 MAK MYLK POLR2A GNPTAB PAK4 MAP3K20 PAK6 TESK1 TAOK2 PASK STK11 MAPK14 MAPK12 KDR TAOK1 PRKDC MAPK1 MAPK11 MAP4K4 HCK EPHA3	1.45e-06	938	147	22	GO:0016772
GeneOntologyMolecularFunction	MAP kinase activity	MAPK14 MAPK12 MAPK1 MAPK11	4.79e-06	16	147	4	GO:0004707
GeneOntologyMolecularFunction	glucan 1,4-alpha-glucosidase activity	MGAM MGAM2	5.38e-05	2	147	2	GO:0004339
GeneOntologyMolecularFunction	monoacylglycerol lipase activity	ABHD3 ABHD16B DAGLA	2.04e-04	16	147	3	GO:0047372
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	MGAM MGAM2	5.31e-04	5	147	2	GO:0004558
GeneOntologyMolecularFunction	calcium, potassium:sodium antiporter activity	SLC24A3 SLC24A4	5.31e-04	5	147	2	GO:0008273
GeneOntologyMolecularFunction	lipase activity	CEL ABHD3 ABHD4 ABHD16B DDHD1 DAGLA	5.56e-04	138	147	6	GO:0016298
GeneOntologyMolecularFunction	hydrolase activity, acting on glycosyl bonds	MGAM GLB1L3 MAN1C1 MYORG IL1RAPL1 MGAM2	6.96e-04	144	147	6	GO:0016798
GeneOntologyMolecularFunction	lysophosphatidic acid acyltransferase activity	MBOAT7 ABHD4 GPAT4	7.06e-04	24	147	3	GO:0042171
GeneOntologyMolecularFunction	lysophospholipid acyltransferase activity	MBOAT7 ABHD4 GPAT4	7.06e-04	24	147	3	GO:0071617
GeneOntologyMolecularFunction	acetylesterase activity	CEL ABHD3	7.92e-04	6	147	2	GO:0008126
GeneOntologyMolecularFunction	O-acyltransferase activity	MBOAT7 DGAT2L6 CPT1C GPAT4	9.37e-04	59	147	4	GO:0008374
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	MGAM GLB1L3 MAN1C1 MYORG MGAM2	9.91e-04	103	147	5	GO:0004553
GeneOntologyMolecularFunction	carboxylic ester hydrolase activity	CEL ABHD3 ABHD4 ABHD16B DDHD1 DAGLA	1.09e-03	157	147	6	GO:0052689
GeneOntologyMolecularFunction	short-chain carboxylesterase activity	CEL ABHD3	1.10e-03	7	147	2	GO:0034338
GeneOntologyMolecularFunction	alpha-glucosidase activity	MGAM MGAM2	1.10e-03	7	147	2	GO:0090599
GeneOntologyMolecularFunction	phospholipase activity	CEL ABHD3 ABHD4 ABHD16B DDHD1	1.56e-03	114	147	5	GO:0004620
GeneOntologyMolecularFunction	acylglycerol O-acyltransferase activity	MBOAT7 DGAT2L6 GPAT4	1.66e-03	32	147	3	GO:0016411
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC24A3 SLC5A2 SLC24A4 SLC28A1 SLC41A1 SLC4A5	1.69e-03	171	147	6	GO:0015081
GeneOntologyBiologicalProcess	cellular response to UV-B	MAP3K20 STK11 MAPK14 MAPK11	1.11e-06	12	145	4	GO:0071493
GeneOntologyBiologicalProcess	stress-activated MAPK cascade	MAP3K20 TAOK2 MAPK14 TAOK1 MAPK1 MAPK11	4.39e-06	61	145	6	GO:0051403
GeneOntologyBiologicalProcess	stress-activated protein kinase signaling cascade	MAP3K20 TAOK2 MAPK14 TAOK1 MAPK1 MAPK11	9.06e-06	69	145	6	GO:0031098
GeneOntologyBiologicalProcess	response to UV-B	MAP3K20 STK11 MAPK14 MAPK11	1.28e-05	21	145	4	GO:0010224
GeneOntologyBiologicalProcess	cell morphogenesis	PLOD3 ZFYVE27 NCKAP1 DOCK10 PAK6 TAOK2 IL1RAPL1 STK11 CRYGB MAPK14 CELSR3 TET1 LHFPL5 KDR UNC93B1 PRKDC MAP4K4 HCK ZMYM4 CNTN2 CNTN1 EPHA3	3.13e-05	1194	145	22	GO:0000902
GeneOntologyBiologicalProcess	protein autophosphorylation	MAK MAP3K20 TESK1 TAOK2 PASK STK11 KDR TAOK1 HCK	3.47e-05	228	145	9	GO:0046777
GeneOntologyBiologicalProcess	positive regulation of protein metabolic process	CACUL1 SASH1 PSEN2 GAS6 FBXO11 KEAP1 FASLG TESK1 AXIN2 TAOK2 PASK STK11 AKTIP LRRN3 MAPK12 APH1A SECISBP2 FNIP1 KDR TAOK1 PRKDC MAPK1 CNTN2 CNTN1	7.95e-05	1458	145	24	GO:0051247
GeneOntologyCellularComponent	endosome	ZFYVE27 PSEN2 AVPR1A HAP1 VPS13C ATP13A5 ATP9B ABHD17C GPR161 NEURL3 AP1B1 APH1A NISCH MTM1 STOML1 ASTN1 ASTN2 KDR UNC93B1 MAPK1 DAGLA EPHA3	1.61e-05	1167	144	22	GO:0005768
Domain	Protein_kinase_ATP_BS	CDK18 MAK MYLK PAK4 PAK6 TESK1 TAOK2 PASK STK11 MAPK14 MAPK12 KDR TAOK1 MAPK1 MAPK11 MAP4K4 HCK EPHA3	9.08e-10	379	145	18	IPR017441
Domain	PROTEIN_KINASE_ATP	CDK18 MAK MYLK PAK4 MAP3K20 PAK6 TESK1 TAOK2 PASK STK11 MAPK14 MAPK12 KDR TAOK1 MAPK1 MAPK11 MAP4K4 HCK EPHA3	2.92e-09	459	145	19	PS00107
Domain	Kinase-like_dom	CDK18 MAK MYLK PAK4 MAP3K20 PAK6 TESK1 TAOK2 PASK STK11 MAPK14 MAPK12 KDR TAOK1 PRKDC MAPK1 MAPK11 MAP4K4 HCK EPHA3	7.66e-09	542	145	20	IPR011009
Domain	Prot_kinase_dom	CDK18 MAK MYLK PAK4 MAP3K20 PAK6 TESK1 TAOK2 PASK STK11 MAPK14 MAPK12 KDR TAOK1 MAPK1 MAPK11 MAP4K4 HCK EPHA3	8.20e-09	489	145	19	IPR000719
Domain	PROTEIN_KINASE_DOM	CDK18 MAK MYLK PAK4 MAP3K20 PAK6 TESK1 TAOK2 PASK STK11 MAPK14 MAPK12 KDR TAOK1 MAPK1 MAPK11 MAP4K4 HCK EPHA3	9.35e-09	493	145	19	PS50011
Domain	Ser/Thr_kinase_AS	CDK18 MAK MYLK PAK4 MAP3K20 PAK6 TAOK2 PASK STK11 MAPK14 MAPK12 TAOK1 MAPK1 MAPK11 MAP4K4	1.24e-07	357	145	15	IPR008271
Domain	S_TKc	CDK18 MAK MYLK PAK4 MAP3K20 PAK6 TAOK2 PASK STK11 MAPK14 MAPK12 TAOK1 MAPK1 MAPK11 MAP4K4	1.34e-07	359	145	15	SM00220
Domain	PROTEIN_KINASE_ST	CDK18 MAK MYLK PAK4 MAP3K20 PAK6 TAOK2 PASK STK11 MAPK14 MAPK12 TAOK1 MAPK1 MAPK11 MAP4K4	1.49e-07	362	145	15	PS00108
Domain	Pkinase	CDK18 MAK MYLK PAK4 PAK6 TESK1 TAOK2 PASK STK11 MAPK14 MAPK12 TAOK1 MAPK1 MAPK11 MAP4K4	2.87e-07	381	145	15	PF00069
Domain	MAPK	MAPK14 MAPK12 MAPK1 MAPK11	1.64e-06	12	145	4	PS01351
Domain	MAP_kinase_CS	MAPK14 MAPK12 MAPK1 MAPK11	1.64e-06	12	145	4	IPR003527
Domain	MAPK_p38	MAPK14 MAPK12 MAPK11	1.82e-06	4	145	3	IPR008352
Domain	Glyco_hydro_31	MGAM MYORG MGAM2	1.57e-05	7	145	3	IPR000322
Domain	Glyco_hydro_31	MGAM MYORG MGAM2	1.57e-05	7	145	3	PF01055
Domain	GLYCOSYL_HYDROL_F31_1	MGAM MYORG MGAM2	1.57e-05	7	145	3	PS00129
Domain	Astrotactin	ASTN1 ASTN2	5.99e-05	2	145	2	IPR026995
Domain	FN3	MYLK IL20RB LRRN3 ASTN1 ASTN2 CNTN2 CNTN1 EPHA3	9.99e-05	185	145	8	SM00060
Domain	FN3	MYLK IL20RB LRRN3 ASTN1 ASTN2 CNTN2 CNTN1 EPHA3	1.65e-04	199	145	8	PS50853
Domain	FN3_dom	MYLK IL20RB LRRN3 ASTN1 ASTN2 CNTN2 CNTN1 EPHA3	2.31e-04	209	145	8	IPR003961
Domain	Gal_mutarotase_N	MGAM MGAM2	3.56e-04	4	145	2	IPR031727
Domain	NtCtMGAM_N	MGAM MGAM2	3.56e-04	4	145	2	PF16863
Domain	GLYCOSYL_HYDROL_F31_2	MGAM MYORG	5.89e-04	5	145	2	PS00707
Domain	DUF3504	QRICH1 ZMYM4	5.89e-04	5	145	2	IPR021893
Domain	K/Na/Ca-exchanger	SLC24A3 SLC24A4	5.89e-04	5	145	2	IPR004481
Domain	DUF3504	QRICH1 ZMYM4	5.89e-04	5	145	2	PF12012
Domain	Glycoside_hydrolase_SF	MGAM GLB1L3 MYORG MGAM2	7.60e-04	53	145	4	IPR017853
Domain	Glyco_hydro_31_AS	MGAM MGAM2	8.80e-04	6	145	2	IPR030458
Domain	WASP_C	PAK4 PAK6	1.23e-03	7	145	2	IPR011026
Pathway	KEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPF_TO_TLR2_4_MAPK_SIGNALING_PATHWAY	MAPK14 MAPK12 MAPK1 MAPK11	6.67e-08	6	117	4	M47766
Pathway	WP_CANNABINOID_RECEPTOR_SIGNALING	MAPK14 MAPK12 MAPK1 MAPK11 DAGLA	3.66e-06	29	117	5	M39676
Pathway	WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_APOPTOSIS	FASLG MAPK14 MAPK12 MAPK11	2.94e-05	22	117	4	M39902
Pathway	WP_PHOTODYNAMIC_THERAPYINDUCED_NFE2L2_NRF2_SURVIVAL_SIGNALING	KEAP1 MAPK14 MAPK12 MAPK11	3.53e-05	23	117	4	M39709
Pathway	WP_MAPK_SIGNALING	MAP3K20 FASLG TAOK2 CACNA2D4 MAPK14 MAPK12 TAOK1 MAPK1 MAPK11 MAP4K4	3.79e-05	246	117	10	M39597
Pathway	WP_ATM_SIGNALING_IN_DEVELOPMENT_AND_DISEASE	STK11 MAPK14 MAPK12 PRKDC MAPK11	4.20e-05	47	117	5	M39518
Pathway	WP_MAPK_SIGNALING_PATHWAY	MAP3K20 FASLG TAOK2 MAPK14 MAPK12 TAOK1 MAPK1 MAP4K4	5.53e-05	160	117	8	MM15990
Pathway	PID_P38_MKK3_6PATHWAY	TAOK2 MAPK14 TAOK1 MAPK11	5.85e-05	26	117	4	M20
Pathway	KEGG_MEDICUS_REFERENCE_TLR2_4_MAPK_SIGNALING_PATHWAY	MAPK14 MAPK12 MAPK1 MAPK11	5.85e-05	26	117	4	M47565
Pathway	REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS	MBOAT7 STARD10 ABHD3 DGAT2L6 ABHD4 DDHD1 GPAT4	6.22e-05	120	117	7	MM14585
Pathway	REACTOME_ACTIVATION_OF_PPARGC1A_PGC_1ALPHA_BY_PHOSPHORYLATION	MAPK14 MAPK12 MAPK11	6.41e-05	10	117	3	M27146
Pathway	REACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS	MAPK14 MAPK1 MAPK11	6.41e-05	10	117	3	MM15135
Pathway	REACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS	MAPK14 MAPK1 MAPK11	6.41e-05	10	117	3	M13962
Pathway	WP_FGFR3_SIGNALING_IN_CHONDROCYTE_PROLIFERATION_AND_TERMINAL_DIFFERENTIATION	MAPK14 MAPK12 MAPK1 MAPK11	6.82e-05	27	117	4	M39838
Pathway	KEGG_MAPK_SIGNALING_PATHWAY	MAP3K20 FASLG TAOK2 CACNA2D4 MAPK14 MAPK12 TAOK1 MAPK1 MAPK11 MAP4K4	7.55e-05	267	117	10	M10792
Pathway	WP_NANOPARTICLEMEDIATED_ACTIVATION_OF_RECEPTOR_SIGNALING	MAPK14 MAPK12 MAPK1 MAPK11	7.91e-05	28	117	4	M39572
Pathway	REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS	MBOAT7 STARD10 ABHD3 DGAT2L6 ABHD4 DDHD1 GPAT4	9.36e-05	128	117	7	M706
Pathway	REACTOME_P38MAPK_EVENTS	MAPK14 MAPK12 MAPK11	1.50e-04	13	117	3	M1441
Pathway	REACTOME_SIGNALLING_TO_ERKS	MAPK14 MAPK12 MAPK1 MAPK11	1.72e-04	34	117	4	M13881
Pathway	SIG_CD40PATHWAYMAP	MAPK14 MAPK12 MAPK1 MAPK11	1.72e-04	34	117	4	M12705
Pathway	WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_MAPK_SIGNALING	MAPK14 MAPK12 MAPK1 MAPK11	2.16e-04	36	117	4	M39908
Pathway	REACTOME_PHOSPHOLIPID_METABOLISM	MBOAT7 STARD10 ABHD3 DGAT2L6 ABHD4 DDHD1 MTM1 GPAT4	2.26e-04	196	117	8	MM14591
Pathway	REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE	MAPK14 MAPK1 MAPK11 MAP4K4	2.41e-04	37	117	4	MM14899
Pathway	KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY	PAK4 PAK6 MAPK14 MAPK12 MAPK1 MAPK11	2.76e-04	108	117	6	M9904
Pathway	REACTOME_PHOSPHOLIPID_METABOLISM	MBOAT7 STARD10 ABHD3 DGAT2L6 ABHD4 DDHD1 MTM1 GPAT4	3.72e-04	211	117	8	M649
Pathway	KEGG_VEGF_SIGNALING_PATHWAY	MAPK14 MAPK12 KDR MAPK1 MAPK11	4.18e-04	76	117	5	M1749
Pathway	BIOCARTA_MAPK_PATHWAY	MAPK14 MAPK12 MAPK1 MAPK11 MAP4K4	4.18e-04	76	117	5	MM1433
Pathway	WP_REGULATORY_CIRCUITS_OF_STAT3_SIGNALING	IL20RB MAPK14 MAPK12 MAPK1 MAPK11	4.71e-04	78	117	5	M39824
Pathway	KEGG_LYSINE_DEGRADATION	PLOD3 SETD1B PIPOX SETDB1	4.74e-04	44	117	4	M13720
Pathway	REACTOME_ERK_MAPK_TARGETS	MAPK14 MAPK1 MAPK11	4.90e-04	19	117	3	MM14780
Pathway	BIOCARTA_MAPK_PATHWAY	MAPK14 MAPK12 MAPK1 MAPK11 MAP4K4	5.60e-04	81	117	5	M13863
Pathway	BIOCARTA_ARENRF2_PATHWAY	KEAP1 MAPK14 MAPK1	5.73e-04	20	117	3	M14339
Pathway	REACTOME_SIGNALLING_TO_RAS	MAPK14 MAPK12 MAPK11	5.73e-04	20	117	3	M12256
Pathway	REACTOME_ERK_MAPK_TARGETS	MAPK14 MAPK1 MAPK11	7.65e-04	22	117	3	M13408
Pathway	BIOCARTA_ARENRF2_PATHWAY	KEAP1 MAPK14 MAPK1	7.65e-04	22	117	3	MM1449
Pathway	REACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS	PSEN2 APH1A CNTN1	7.65e-04	22	117	3	M27210
Pathway	WP_PHOTODYNAMIC_THERAPYINDUCED_AP1_SURVIVAL_SIGNALING	FASLG MAPK14 MAPK12 MAPK11	8.34e-04	51	117	4	M39438
Pathway	WP_LDL_INFLUENCE_ON_CD14_AND_TLR4	MAPK14 MAPK12 MAPK11	8.74e-04	23	117	3	M45556
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_NADPH_OXIDASES	MAPK14 MAPK1 MAPK11	9.93e-04	24	117	3	M27553
Pathway	REACTOME_MYOGENESIS	MAPK14 MAPK12 MAPK11	9.93e-04	24	117	3	MM15174
Pathway	WP_PHYSIOLOGICAL_AND_PATHOLOGICAL_HYPERTROPHY_OF_THE_HEART	MAPK14 MAPK1 MAPK11	9.93e-04	24	117	3	M39576
Pathway	WP_ANGIOGENESIS	MAPK14 KDR MAPK1	9.93e-04	24	117	3	M39556
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_NADPH_OXIDASES	MAPK14 MAPK1 MAPK11	1.12e-03	25	117	3	MM15269
Pathway	PID_LYMPH_ANGIOGENESIS_PATHWAY	MAPK14 MAPK1 MAPK11	1.12e-03	25	117	3	M274
Pathway	REACTOME_SIGNALLING_TO_ERKS	MAPK14 MAPK1 MAPK11	1.26e-03	26	117	3	MM14716
Pathway	WP_PARKINSONS_DISEASE	MAPK14 UBE2J2 MAPK12 MAPK11	1.27e-03	57	117	4	MM15899
Pubmed	Regulation of a mitogen-activated protein kinase kinase kinase, MLTK by PKN.	MAP3K20 MAPK14 MAPK12 MAPK11	2.12e-08	8	147	4	12761180
Pubmed	Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.	CDK18 PAK4 MAP3K20 MAPK14 MAPK1 MAP4K4 EPHA3	4.29e-08	78	147	7	17192257
Pubmed	TGF-β1 induces endothelial cell apoptosis by shifting VEGF activation of p38(MAPK) from the prosurvival p38β to proapoptotic p38α.	MAPK14 MAPK12 MAPK11	7.40e-08	3	147	3	22522454
Pubmed	Involvement of the p38 mitogen-activated protein kinase alpha, beta, and gamma isoforms in myogenic differentiation.	MAPK14 MAPK12 MAPK11	7.40e-08	3	147	3	18256287
Pubmed	The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.	MAPK14 MAPK12 MAPK1 MAPK11	2.13e-07	13	147	4	17906618
Pubmed	Essential role for p38alpha MAPK but not p38gamma MAPK in Igf2 expression and myoblast differentiation.	MAPK14 MAPK12 MAPK11	2.95e-07	4	147	3	20610565
Pubmed	Role for mitogen-activated protein kinase p38 alpha in lung epithelial branching morphogenesis.	MAPK14 MAPK12 MAPK11	2.95e-07	4	147	3	18177852
Pubmed	p38gamma mitogen-activated protein kinase is a key regulator in skeletal muscle metabolic adaptation in mice.	MAPK14 MAPK12 MAPK11	2.95e-07	4	147	3	19936205
Pubmed	Murine p38-delta mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines.	MAPK14 MAPK12 MAPK11	2.95e-07	4	147	3	10066767
Pubmed	gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes.	MAPK14 MAPK12 MAPK1 MAPK11	2.97e-07	14	147	4	12239168
Pubmed	PRAK, a novel protein kinase regulated by the p38 MAP kinase.	MAPK14 MAPK12 MAPK1 MAPK11	4.03e-07	15	147	4	9628874
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SASH1 VPS13C PAK4 KEAP1 TAOK2 PASK CELSR3 DDHD1 TET1 ARHGAP20 MAP4K4 DAGLA ZMYM4	4.39e-07	529	147	13	14621295
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	SOX10 SETD1B MYLK TOR2A POLR2A PAK4 KEAP1 MAPK14 MAPK12 AP1B1 MTM1 MAPK1 MAPK11 USP15 HCK	5.36e-07	730	147	15	34857952
Pubmed	Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38.	TAOK2 MAPK14 TAOK1	7.35e-07	5	147	3	13679851
Pubmed	ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome.	MAP3K20 MAPK14 MAPK11	7.35e-07	5	147	3	35857590
Pubmed	Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38delta at Thr50 promotes microtubule assembly.	MAPK14 MAPK12 MAPK11	7.35e-07	5	147	3	15632108
Pubmed	Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation.	MAPK14 MAPK12 MAPK11	7.35e-07	5	147	3	17304211
Pubmed	RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1.	MAPK14 MAPK12 MAPK1 MAPK11	1.41e-06	20	147	4	32662771
Pubmed	Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice.	MAPK14 MAPK12 MAPK11	1.47e-06	6	147	3	27856911
Pubmed	Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta.	MAPK14 MAPK12 MAPK11	1.47e-06	6	147	3	14680475
Pubmed	p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.	MAPK14 MAPK12 MAPK11 MAP4K4	2.11e-06	22	147	4	16751104
Pubmed	p38 MAPK signalling cascades: ancient roles and new functions.	MAPK14 MAPK1 MAPK11	2.56e-06	7	147	3	10878576
Pubmed	F-box Protein βTrCP1 Is a Substrate of Extracellular Signal-regulated Kinase 2.	MAPK14 MAPK1 MAPK11	4.08e-06	8	147	3	34703820
Pubmed	Pax3 lineage-specific deletion of Gpr161 is associated with spinal neural tube and craniofacial malformations during embryonic development.	SOX10 AXIN2 GPR161	4.08e-06	8	147	3	37885410
Pubmed	Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2.	MAPK14 MAPK1 MAPK11	4.08e-06	8	147	3	9155017
Pubmed	Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.	MYLK FASLG F8 TAOK2 STK11 MAPK14 MAPK12 MAPK1 MAPK11 HCK	4.40e-06	371	147	10	25241761
Pubmed	Deletion of Pdcd5 in mice led to the deficiency of placenta development and embryonic lethality.	STK11 MAPK14 KDR MAPK1	4.98e-06	27	147	4	28542142
Pubmed	Regulation of stress-responsive mitogen-activated protein (MAP) kinase pathways by TAO2.	TAOK2 MAPK14 MAPK1	6.10e-06	9	147	3	11279118
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	PLOD3 MYLK NCKAP1 PAK4 GAS6 MAP3K20 AXIN2 STK11 MAPK14 AP1B1 NUP133 MAPK1 MAPK11 MAP4K4 HCK	7.87e-06	910	147	15	36736316
Pubmed	MAPK-upstream protein kinase (MUK) regulates the radial migration of immature neurons in telencephalon of mouse embryo.	MAPK14 MAPK12 MAPK1	8.69e-06	10	147	3	12223406
Pubmed	Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases.	MAPK12 MAPK1 MAPK11	8.69e-06	10	147	3	9199504
Pubmed	The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.	STK11 MAPK14 MAPK1	8.69e-06	10	147	3	14985505
Pubmed	Critical roles for Akt kinase in controlling HIV envelope-mediated depletion of CD4 T cells.	FASLG MAPK14 MAPK1	1.19e-05	11	147	3	23742646
Pubmed	Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways.	MAPK14 MAPK12 MAPK11	1.58e-05	12	147	3	12171600
Pubmed	MAP4K4 is involved in the neuronal development of retinal photoreceptors.	MAPK14 MAPK1 MAP4K4	1.58e-05	12	147	3	37290629
Pubmed	Fasting-induced activation of mitogen-activated protein kinases (ERK/p38) in the mouse hypothalamus.	MAPK14 MAPK1	1.77e-05	2	147	2	14763996
Pubmed	Virus-induced inhibition of CD1d1-mediated antigen presentation: reciprocal regulation by p38 and ERK.	MAPK14 MAPK1	1.77e-05	2	147	2	16177070
Pubmed	Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38.	KDR MAPK11	1.77e-05	2	147	2	14724572
Pubmed	RF9 Acts as a KISS1R Agonist In Vivo and In Vitro.	NPFFR1 KISS1R	1.77e-05	2	147	2	26418326
Pubmed	The p38alpha/beta MAPK functions as a molecular switch to activate the quiescent satellite cell.	MAPK14 MAPK11	1.77e-05	2	147	2	15824134
Pubmed	p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms.	MAPK14 MAPK12	1.77e-05	2	147	2	19251701
Pubmed	Inherent low Erk and p38 activity reduce Fas Ligand expression and degranulation in T helper 17 cells leading to activation induced cell death resistance.	MAPK14 MAPK1	1.77e-05	2	147	2	27486885
Pubmed	p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice.	MAPK14 MAPK11	1.77e-05	2	147	2	24531379
Pubmed	p38 Mitogen-activated protein kinase regulates chamber-specific perinatal growth in heart.	MAPK14 MAPK11	1.77e-05	2	147	2	32573492
Pubmed	Effect of p38 MAP kinases on contractility and ischemic injury in intact heart.	MAPK14 MAPK11	1.77e-05	2	147	2	19706373
Pubmed	Loss of SETDB1 decompacts the inactive X chromosome in part through reactivation of an enhancer in the IL1RAPL1 gene.	IL1RAPL1 SETDB1	1.77e-05	2	147	2	30103804
Pubmed	STK11/LKB1 and KEAP1 mutations in non-small cell lung cancer: Prognostic rather than predictive?	KEAP1 STK11	1.77e-05	2	147	2	34500370
Pubmed	Involvement of p38 MAPK in Leydig cell aging and age-related decline in testosterone.	MAPK14 MAPK1	1.77e-05	2	147	2	36950685
Pubmed	Differential Involvement of ERK2 and p38 in platelet adhesion to collagen.	MAPK14 MAPK1	1.77e-05	2	147	2	15851480
Pubmed	Advancements in MAPK signaling pathways and MAPK-targeted therapies for ameloblastoma: A review.	MAPK14 MAPK1	1.77e-05	2	147	2	30489659
Pubmed	Counter-regulation of T cell effector function by differentially activated p38.	MAPK14 MAPK11	1.77e-05	2	147	2	24863062
Pubmed	BPTF Maintains Chromatin Accessibility and the Self-Renewal Capacity of Mammary Gland Stem Cells.	BPTF PRKDC	1.77e-05	2	147	2	28579392
Pubmed	Delayed inhibition of ERK and p38 attenuates neuropathic pain without affecting motor function recovery after peripheral nerve injury.	MAPK14 MAPK1	1.77e-05	2	147	2	34648772
Pubmed	p38alpha antagonizes p38gamma activity through c-Jun-dependent ubiquitin-proteasome pathways in regulating Ras transformation and stress response.	MAPK14 MAPK12	1.77e-05	2	147	2	17724032
Pubmed	p38 (Mapk14/11) occupies a regulatory node governing entry into primitive endoderm differentiation during preimplantation mouse embryo development.	MAPK14 MAPK11	1.77e-05	2	147	2	27605380
Pubmed	The activation of p38 alpha, and not p38 beta, mitogen-activated protein kinase is required for ischemic preconditioning.	MAPK14 MAPK11	1.77e-05	2	147	2	20188737
Pubmed	SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases.	MAPK14 MAPK12	1.77e-05	2	147	2	8925912
Pubmed	Fenretinide inhibits the proliferation and migration of human liver cancer HepG2 cells by downregulating the activation of myosin light chain kinase through the p38‑MAPK signaling pathway.	MYLK MAPK1	1.77e-05	2	147	2	29767236
Pubmed	Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells.	TAOK2 TAOK1	1.77e-05	2	147	2	28830982
Pubmed	Critical role of p38 MAPK for regeneration of the sciatic nerve following crush injury in vivo.	MAPK14 MAPK1	1.77e-05	2	147	2	23282009
Pubmed	Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation.	MAPK14 MAPK11	1.77e-05	2	147	2	29357353
Pubmed	Murine astrotactins 1 and 2 have a similar membrane topology and mature via endoproteolytic cleavage catalyzed by a signal peptidase.	ASTN1 ASTN2	1.77e-05	2	147	2	30696770
Pubmed	HIV-1 activates macrophages independent of Toll-like receptors.	MAPK14 MAPK1	1.77e-05	2	147	2	19048100
Pubmed	Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway.	MAPK14 MAPK1	1.77e-05	2	147	2	18957688
Pubmed	Anti-tumor effect of CT-322 as an adnectin inhibitor of vascular endothelial growth factor receptor-2.	KDR MAPK1	1.77e-05	2	147	2	20190562
Pubmed	High expression of PRKDC promotes breast cancer cell growth via p38 MAPK signaling and is associated with poor survival.	MAPK14 PRKDC	1.77e-05	2	147	2	31513357
Pubmed	Ectopic expression of Fas Ligand on cardiomyocytes renders cardiac allografts resistant to CD4(+) T-cell mediated rejection.	FASLG PRKDC	1.77e-05	2	147	2	25497973
Pubmed	Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways.	MAPK14 MAPK1	1.77e-05	2	147	2	25831013
Pubmed	Insertional mutagenesis affecting programmed cell death leads to thymic hyperplasia and altered thymopoiesis.	AKTIP PRKDC	1.77e-05	2	147	2	8598454
Pubmed	In vitro cultured progenitors and precursors of cardiac cell lineages from human normal and post-ischemic hearts.	F8 KDR	1.77e-05	2	147	2	18162457
Pubmed	STK11 and KEAP1 mutations in non-small cell lung cancer patients: Descriptive analysis and prognostic value among Hispanics (STRIKE registry-CLICaP).	KEAP1 STK11	1.77e-05	2	147	2	35753125
Pubmed	Convergence of Igf2 expression and adhesion signalling via RhoA and p38 MAPK enhances myogenic differentiation.	MAPK14 MAPK11	1.77e-05	2	147	2	17105766
Pubmed	Active mutants of the human p38alpha mitogen-activated protein kinase.	MAPK14 MAPK12	1.77e-05	2	147	2	15284239
Pubmed	p38α and p38β mitogen-activated protein kinases determine cholinergic transdifferentiation of sympathetic neurons.	MAPK14 MAPK11	1.77e-05	2	147	2	21865449
Pubmed	HIV-1 Nef-induced FasL induction and bystander killing requires p38 MAPK activation.	FASLG MAPK1	1.77e-05	2	147	2	15928037
Pubmed	Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin.	MAPK14 MAPK1	1.77e-05	2	147	2	16476765
Pubmed	Intrinsically active variants of all human p38 isoforms.	MAPK14 MAPK11	1.77e-05	2	147	2	17241234
Pubmed	Exploring the dynamics of adult Axin2 cell lineage integration into dentate gyrus granule neurons.	POLR2A AXIN2	1.77e-05	2	147	2	38449734
Pubmed	p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting.	MAPK14 MAPK11	1.77e-05	2	147	2	19955483
Pubmed	Integrin-binding protein nischarin interacts with tumor suppressor liver kinase B1 (LKB1) to regulate cell migration of breast epithelial cells.	STK11 NISCH	1.77e-05	2	147	2	23572524
Pubmed	Contactin-1 Is Reduced in Cerebrospinal Fluid of Parkinson's Disease Patients and Is Present within Lewy Bodies.	CNTN2 CNTN1	1.77e-05	2	147	2	32806791
Pubmed	Roles of p38α and p38β mitogen‑activated protein kinase isoforms in human malignant melanoma A375 cells.	MAPK14 MAPK11	1.77e-05	2	147	2	31661126
Pubmed	STK11 and KEAP1 mutations as prognostic biomarkers in an observational real-world lung adenocarcinoma cohort.	KEAP1 STK11	1.77e-05	2	147	2	32312757
Pubmed	Interferon-alpha induces the growth inhibition of human T-cell leukaemia line Jurkat through p38alpha and p38beta.	MAPK14 MAPK11	1.77e-05	2	147	2	20053787
Pubmed	LKB1 reduces ROS-mediated cell damage via activation of p38.	STK11 MAPK14	1.77e-05	2	147	2	25263448
Pubmed	Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells.	MAPK14 NID1 MAPK1	2.60e-05	14	147	3	26724533
Pubmed	Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB.	MAPK14 MAPK1 MAPK11	2.60e-05	14	147	3	9687510
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	CDK18 WSB2 PAK6 TESK1 PASK STK11 SETDB1 MAP4K4 HCK	3.13e-05	372	147	9	22939624
Pubmed	Integrin-linked kinase regulates p38 MAPK-dependent cell cycle arrest in ureteric bud development.	MAPK14 NID1 MAPK1	3.98e-05	16	147	3	20823064
Pubmed	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	CHRNA6 HTR1F AVPR1A GLRB ASTN1 ASTN2 CNTN2 CNTN1	4.41e-05	300	147	8	19086053
Pubmed	The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells.	AXIN2 MAPK14 MAPK1	4.82e-05	17	147	3	26542706
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	NCKAP1 MBOAT7 LMBR1 QRICH1 TAOK2 STXBP3 AP1B1 APH1A NISCH SEC62 NUP133 LSS PRKDC MAPK1	4.95e-05	942	147	14	31073040
Pubmed	The Macrophage Activation Induced by Bacillus thuringiensis Cry1Ac Protoxin Involves ERK1/2 and p38 Pathways and the Interaction with Cell-Surface-HSP70.	MAPK14 MAPK1	5.31e-05	3	147	2	28608568
Pubmed	The p38alpha/beta mitogen-activated protein kinases mediate recruitment of CREB-binding protein to preserve fast myosin heavy chain IId/x gene activity in myotubes.	MAPK14 MAPK11	5.31e-05	3	147	2	17210568
Pubmed	Diminished Efficacy of Programmed Death-(Ligand)1 Inhibition in STK11- and KEAP1-Mutant Lung Adenocarcinoma Is Affected by KRAS Mutation Status.	KEAP1 STK11	5.31e-05	3	147	2	34740862
Pubmed	TAO (thousand-and-one amino acid) protein kinases mediate signaling from carbachol to p38 mitogen-activated protein kinase and ternary complex factors.	TAOK2 MAPK1	5.31e-05	3	147	2	12665513
Pubmed	Hydrogen-exchange mass spectrometry reveals activation-induced changes in the conformational mobility of p38alpha MAP kinase.	MAPK14 MAPK1	5.31e-05	3	147	2	18501927
Pubmed	Metal-dependent protein phosphatase 1A functions as an extracellular signal-regulated kinase phosphatase.	MAPK14 MAPK1	5.31e-05	3	147	2	23560844
Pubmed	Significant role for Fas in the pathogenesis of autoimmune diabetes.	FASLG PRKDC	5.31e-05	3	147	2	10679090
Pubmed	Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-kappaB transcription factors.	MAPK14 MAPK1	5.31e-05	3	147	2	17187070
Interaction	MAP2K6 interactions	MAP3K20 PAK6 TAOK2 STK11 MAPK14 MAPK12 MAPK1	1.04e-06	74	145	7	int:MAP2K6
GeneFamily	Mitogen-activated protein kinases	MAPK14 MAPK12 MAPK1 MAPK11	5.36e-07	13	97	4	651
GeneFamily	Fibronectin type III domain containing	MYLK IL20RB LRRN3 ASTN1 ASTN2 CNTN2 CNTN1 EPHA3	2.34e-06	160	97	8	555
GeneFamily	Abhydrolase domain containing	ABHD3 ABHD17C ABHD4 ABHD16B	5.29e-06	22	97	4	4
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	MYLK IL1RAPL1 LRRN3 KDR CNTN2 CNTN1	2.30e-04	161	97	6	593
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K20 TAOK2 TAOK1	2.79e-04	24	97	3	654
GeneFamily	Solute carriers	SLC24A3 SLC5A2 SLC24A4 SLC28A1 SLC41A1 SLC22A20P SLC4A5 SLC7A10	1.29e-03	395	97	8	752
Coexpression	GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN	TOR2A IL20RB PAK6 ABHD4 CACNA2D4 AP1B1 NISCH STOML1 ZMYM4	1.82e-06	200	145	9	M6372
Coexpression	GSE5503_LIVER_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP	MAK STARD10 XKR8 PAK6 TMEM200A SLC5A2 SETDB1 CACNA2D4 TET1	1.82e-06	200	145	9	M6996
Coexpression	GSE17721_LPS_VS_PAM3CSK4_1H_BMDC_DN	ABHD3 FASLG ABHD17C UBE2J2 KDR TAOK1 SLC41A1 EPHA3	1.57e-05	199	145	8	M3912
Coexpression	YOSHIMURA_MAPK8_TARGETS_UP	SOX10 CHRNA6 NAT8B MAK DRD3 DEAF1 HTR1F GAS6 AQP6 SLC5A2 FAT2 MAPK14 NEURL3 MAPK12 APH1A SLC28A1 HAL HCK CNTN2 CNTN1	2.70e-05	1281	145	20	M1884
Coexpression	LIU_OVARIAN_CANCER_TUMORS_AND_XENOGRAFTS_KINASES_DN	KDR MAPK11 HCK EPHA3	2.86e-05	32	145	4	MM17
Coexpression	LIU_OVARIAN_CANCER_TUMORS_AND_XENOGRAFTS_KINASES_DN	KDR MAPK11 HCK EPHA3	3.66e-05	34	145	4	M45005
Coexpression	GRYDER_PAX3FOXO1_ENHANCERS_IN_TADS	TBX15 C2orf69 CACUL1 DEAF1 SASH1 NCKAP1 MAN1C1 DOCK10 PIPOX SLC24A3 WSB2 ATP9B AP1B1 STOML1 ASTN2 USP15 MAP4K4	4.49e-05	1009	145	17	M157
CoexpressionAtlas	FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#4	HAP1 ADGRG1 ADGRL1 SLC24A3 WSB2 TMEM200A SLC5A2 ABHD4 AKTIP MAPK12 CPT1C DDHD1 ASTN1 ASTN2 LSS EPHA3	1.39e-05	683	142	16	Facebase_RNAseq_e9.5_Olfactory Placode_2500_K4
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5	HAP1 ADGRG1 ADGRL1 SLC24A3 WSB2 TMEM200A ALG2 SLC5A2 ABHD4 AKTIP CPT1C DDHD1 ASTN1 ASTN2 LSS EPHA3	3.86e-05	743	142	16	Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K5
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	VPS13C GNPTAB DOCK10 TMEM200A DDHD1 MTM1 PRKDC	2.66e-06	185	146	7	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	VPS13C GNPTAB DOCK10 TMEM200A DDHD1 MTM1 PRKDC	2.75e-06	186	146	7	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	C2orf69 LMBR1 SPIN4 BPTF TAOK1 PRKDC ZMYM4	3.51e-06	193	146	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	(4)_Endothelial_cells-(42)_EC-sinusoidal\|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis	CDK18 MYLK PSEN2 F8 AP1B1 NID1 KDR	3.64e-06	194	146	7	4199900d16623eca02d674d5ada7f0989e47955e
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MYLK DOCK10 SLC24A3 IL1RAPL1 ARHGAP20 CNTN1 EPHA3	3.64e-06	194	146	7	a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCell	facs-Brain_Non-Myeloid-Hippocampus\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 C2orf69 SASH1 DOCK10 ABHD4 GLRB MAP4K4	4.44e-06	200	146	7	fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SOX10 GNPTAB NEURL3 PTCH2 ASTN1 ASTN2 MGAM2	4.44e-06	200	146	7	7c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCell	droplet-Heart-nan-24m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX15 CDK18 DOCK10 LMBR1 ARHGAP20 DAGLA	1.43e-05	159	146	6	7ad3a91d29639b32f6264c91f401c14a35469ac0
Drug	Calcium	DRD3 MYLK PSEN2 AVPR1A ADGRL1 FASLG F8 ALG2 PASK CACNA2D4 MAPK14 KISS1R KDR TAOK1 MAPK1 USP15	1.09e-07	493	145	16	ctd:D002118
Drug	Ac2-26	MAPK14 MAPK12 MAPK11	1.01e-06	4	145	3	CID000568638
Drug	NSC-68458	MAPK14 MAPK12 MAPK11	1.01e-06	4	145	3	CID000249771
Drug	SB202474	MAPK14 MAPK12 MAPK1 MAPK11	1.50e-06	14	145	4	CID000005162
Drug	serotonin	SOX10 MGAM CHRNA6 DRD3 DEAF1 HTR1F AVPR1A POLR2A TAAR6 GPR161 MAPK14 MAPK12 LHFPL5 MAPK1 MAPK11	2.67e-06	554	145	15	CID000005202
Drug	Esculetin [305-01-1]; Up 200; 22.4uM; HL60; HT_HG-U133A	HTR1F MYLK ADGRL1 FASLG TESK1 NPFFR1 LRRN3 CELSR3 KDR	4.98e-06	197	145	9	3120_UP
Drug	tolyltriazole	MAPK14 MAPK12 MAPK11	4.99e-06	6	145	3	CID000025902
Drug	piribedil	DRD3 MAPK14 MAPK12 MAPK1 MAPK11	6.88e-06	42	145	5	CID000004850
Drug	compound 9b	DRD3 MAPK14 MAPK12 MAPK11	7.06e-06	20	145	4	CID000207510
Drug	n-sulfo-2-aminotricarballylate	MAPK14 MAPK12 MAPK1 MAPK11	7.06e-06	20	145	4	CID000135808
Drug	Cp-38	MAPK14 MAPK12 MAPK11	8.69e-06	7	145	3	CID006918286
Drug	satratoxin H	MAPK14 MAPK12 MAPK11	8.69e-06	7	145	3	CID000434380
Drug	2,2',4,6-tetrachlorobiphenyl	MAPK14 MAPK12 MAPK11	8.69e-06	7	145	3	CID000044163
Drug	CID6325568	MAPK14 MAPK12 MAPK11	8.69e-06	7	145	3	CID006325568
Drug	NSC640330	MGAM MAPK14 MAPK12 CPT1C MAPK11	1.34e-05	48	145	5	CID000005204
Drug	Z-D-CH2DCB	MAPK14 MAPK12 MAPK11	1.38e-05	8	145	3	CID009911778
Drug	ML3403	MAPK14 MAPK12 MAPK11	1.38e-05	8	145	3	CID006419739
Drug	VX-745	MAPK14 MAPK12 MAPK11 HCK	1.80e-05	25	145	4	CID003038525
Drug	methyl salicylate	MGAM MAPK14 MAPK12 LSS MAPK11	1.81e-05	51	145	5	CID000004133
Drug	SC68376	MAPK14 MAPK12 MAPK11	2.07e-05	9	145	3	CID000005174
Drug	AMPK inhibitor	GAS6 STK11 MAPK14 MAPK12 FNIP1 MAPK11	2.26e-05	89	145	6	CID011524144
Drug	AC1NOLIT	MAPK14 MAPK12 MAPK11	2.94e-05	10	145	3	CID005090286
Drug	SB220025	MAPK14 MAPK12 MAPK1 MAPK11	3.31e-05	29	145	4	CID000005164
Drug	AG-013608 [351320-38-2]; Down 200; 10uM; PC3; HT_HG-U133A	CDK18 CHRNA6 PDE6C GNPTAB GLRB PRKDC MAPK1 MAPK11	3.41e-05	193	145	8	5909_DN
Drug	Fluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A	PDE6C CEL MAN1C1 PIPOX ADGRL1 FASLG SLC5A2 TAOK2	3.41e-05	193	145	8	3370_UP
Drug	Rifampicin [13292-46-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A	TCN1 SLC24A3 TAOK2 STK11 MTM1 STOML1 LSS DAGLA	3.54e-05	194	145	8	4126_DN
Drug	estradiol; Down 200; 0.01uM; PC3; HT_HG-U133A	PDE6C CEL GNPTAB PIPOX PASK GLRB MAPK1 MAPK11	3.67e-05	195	145	8	5910_DN
Drug	Tacrine hydrochloride hydrate [1684-40-8]; Down 200; 15.8uM; PC3; HT_HG-U133A	PDE6C FBXO11 NPFFR1 PASK MAPK12 CELSR3 SECISBP2 DAGLA	3.67e-05	195	145	8	6698_DN
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	SASH1 PSEN2 GAS6 ADGRL1 SLC24A3 ABHD4 PASK CELSR3	3.67e-05	195	145	8	1045_UP
Drug	Syk inhibitor	MYLK MAPK14 MAPK12 MAPK11 HCK	3.71e-05	59	145	5	CID006419747
Drug	panobinostat	SOX10 MAK MYLK POLR2A PIPOX IL20RB ADGRG1 SLC24A3 AXIN2 IL1RAPL1 LRRN3 KISS1R SUSD2 ASTN1 ASTN2 KDR MAPK1 SLC7A10 HCK CNTN2 CNTN1 EPHA3	3.74e-05	1333	145	22	ctd:C496932
Drug	L001226	MAPK14 MAPK12 MAPK1 MAPK11	3.80e-05	30	145	4	CID004373102
Drug	rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A	HTR1F SETD1B HAP1 MAN1C1 TESK1 PASK DAGLA EPHA3	3.81e-05	196	145	8	5230_UP
Drug	Kawain [500-64-1]; Up 200; 17.4uM; PC3; HT_HG-U133A	SETD1B ADGRL1 ATP9B TAOK2 GPR161 MAPK14 STOML1 ASTN2	3.81e-05	196	145	8	7369_UP
Drug	Benserazide hydrochloride [14919-77-8]; Up 200; 13.6uM; PC3; HT_HG-U133A	MAK HTR1F HAP1 FBXO11 TESK1 TAOK2 LSS MAPK11	3.95e-05	197	145	8	6722_UP
Drug	Enalapril maleate [76095-16-4]; Up 200; 8.2uM; PC3; HT_HG-U133A	NCKAP1 MAN1C1 TAOK2 MAPK14 MAPK12 GLRB NID1 DAGLA	3.95e-05	197	145	8	7265_UP
Drug	nemorosone	MAPK14 MAPK12 MAPK11	4.02e-05	11	145	3	CID000637105
Drug	calcium citrate	MGAM F8	4.03e-05	2	145	2	CID000013136
Drug	4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE	MAPK14 MAPK1	4.03e-05	2	145	2	DB08521
Drug	SB220025	MAPK14 MAPK1	4.03e-05	2	145	2	DB04338
Drug	Adenosine 5'-monophosphate monohydrate [18422-05-4]; Up 200; 11uM; MCF7; HT_HG-U133A	SOX10 SETD1B CEL POLR2A ADGRL1 MTM1 PTCH2 NID1	4.09e-05	198	145	8	3237_UP
Drug	Ketoprofen [22071-15-4]; Down 200; 15.8uM; MCF7; HT_HG-U133A	CDK18 DEAF1 MBOAT7 HAP1 ADGRL1 TAOK2 MTM1 EPHA3	4.09e-05	198	145	8	2316_DN
Drug	PHA-00767505E [723337-45-9]; Up 200; 10uM; MCF7; HT_HG-U133A	SASH1 MBOAT7 GNPTAB DOCK10 NPFFR1 MAPK14 APH1A MTM1	4.09e-05	198	145	8	6550_UP
Drug	Althiazide [5588-16-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A	MYLK SASH1 HAP1 MAN1C1 ADGRL1 SLC24A3 FASLG MAPK14	4.09e-05	198	145	8	6089_DN
Drug	Capsaicin [404-86-4]; Down 200; 13uM; MCF7; HT_HG-U133A	ADGRL1 SLC24A3 NPFFR1 TAOK2 MAPK12 MTM1 MAPK11 EPHA3	4.09e-05	198	145	8	5673_DN
Drug	Remoxipride Hydrochloride [73220-03-8]; Down 200; 9.8uM; PC3; HT_HG-U133A	MYLK NCKAP1 ABHD3 DOCK10 MAPK14 MTM1 SECISBP2 NID1	4.24e-05	199	145	8	6342_DN
Drug	sesamolin	MAPK14 MAPK12 MAPK11	5.34e-05	12	145	3	CID000101746
Drug	MDL-28842	MAPK14 MAPK1 MAPK11	5.34e-05	12	145	3	CID006441200
Drug	ocaperidone	SOX10 DRD3 HTR1F	5.34e-05	12	145	3	CID000071351
Drug	1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one	PAK4 STK11 PRKDC MAPK1	6.31e-05	34	145	4	ctd:C569670
Drug	harmaline	SOX10 FBXO11 GLRB SLC7A10	6.31e-05	34	145	4	CID000022381
Drug	BIRB796	MAPK14 MAPK12 KDR MAPK11 EPHA3	6.39e-05	66	145	5	CID000156422
Drug	lixivaptan	MGAM AVPR1A LSS	6.91e-05	13	145	3	CID000172997
Drug	MnO2	DRD3 AKR1A1 FASLG TAOK2 MAPK14 MAPK12 MAPK11	7.03e-05	158	145	7	CID000014801
Drug	pyridinyl imidazole	MAPK14 MAPK12 MAPK1 MAPK11	7.93e-05	36	145	4	CID000005171
Drug	AICAR monophosphate	AMZ2 STK11 MAPK14 MAPK12 CPT1C MAPK1 MAPK11	8.55e-05	163	145	7	CID000000200
Drug	SB-242235	MAPK14 MAPK12 MAPK11	8.75e-05	14	145	3	CID009863367
Drug	CPI-1189	MAPK14 MAPK12 MAPK11	8.75e-05	14	145	3	CID000151118
Drug	NSC618487	MYLK PSEN2 MBOAT7 PAK4 PAK6 SLC5A2 TAOK2 CACNA2D4 MAPK14 MAPK12 KDR PRKDC MAPK1 MAPK11 DAGLA HCK EPHA3	9.56e-05	933	145	17	CID000005279
Drug	methyl ethyl ketone	MYLK AVPR1A KEAP1 FASLG TAOK2 AKTIP MAPK14 MAPK12 NISCH KDR MAPK1 MAPK11 HCK	1.01e-04	587	145	13	CID000006569
Drug	AC1L1JGQ	AKTIP MAPK14 MAPK12 MAPK1 MAPK11	1.04e-04	73	145	5	CID000005034
Drug	MMP-2 Inhibitor I	MAPK14 MAPK12 MAPK11	1.09e-04	15	145	3	CID000004220
Drug	NGB 2904	DRD3 MAPK1	1.20e-04	3	145	2	ctd:C116818
Drug	Go6983	MAPK14 MAPK12 MAPK1 MAPK11	1.21e-04	40	145	4	CID000003499
Drug	procymidone	MAPK14 MAPK12 MAPK1 MAPK11	1.21e-04	40	145	4	CID000036242
Drug	1,2-naphthoquinone	POLR2A AKR1A1 KEAP1 MAPK1	1.21e-04	40	145	4	ctd:C040756
Drug	DB04790	FASLG MAPK14 MAPK12 MAPK11	1.21e-04	40	145	4	CID005326924
Drug	AC1L1BDQ	AVPR1A MAPK14 MAPK12 SEC62 MAPK11 DAGLA EPHA3	1.24e-04	173	145	7	CID000001394
Drug	3 SA	NCKAP1 MAPK14 MAPK12 MAPK11	1.33e-04	41	145	4	CID000449164
Drug	SF6847	MAPK14 MAPK12 MAPK1 MAPK11	1.33e-04	41	145	4	CID000005614
Drug	SD-282	MAPK14 MAPK12 MAPK11	1.33e-04	16	145	3	CID014973220
Drug	SB 239063	MAPK14 MAPK12 MAPK11	1.33e-04	16	145	3	CID000005166
Drug	AMP 579	MAPK14 MAPK12 MAPK11	1.33e-04	16	145	3	CID006918429
Drug	Clorocruoro Hem	CHRNA6 MYLK MAPK14 MAPK12 MAPK1 MAPK11	1.39e-04	123	145	6	CID003518809
Drug	monomethylarsonous acid	SOX10 MYLK STARD10 GAS6 MAP3K20 ADGRL1 KEAP1 PAK6 TMEM200A MAPK14 DDHD1 SECISBP2 NID1 MAPK1	1.45e-04	694	145	14	ctd:C406082
Drug	1c88	AVPR1A GPR161 MAPK14 MAPK12 MAPK1 MAPK11	1.58e-04	126	145	6	CID000444766
Drug	FSBA	MYLK KEAP1 MAPK14 MAPK12	1.61e-04	43	145	4	CID000133128
Drug	Ambotz208527-57-5	MAPK14 MAPK12 MAPK11	1.61e-04	17	145	3	CID010258704
Drug	dracorhodin	MAPK14 MAPK12 MAPK11	1.61e-04	17	145	3	CID000069509
Drug	kazinol B	MAPK14 MAPK12 MAPK11	1.61e-04	17	145	3	CID000480869
Drug	salinomycin	GAS6 LMBR1 ALG2 SMG8 MAPK14 NID1 MAPK1	1.88e-04	185	145	7	ctd:C010327
Drug	olomoucine	CDK18 MYLK MAPK14 MAPK12 MAPK1 MAPK11	2.04e-04	132	145	6	CID000004592
Drug	oleoyl-lysophosphatidic acid	MYLK MBOAT7 MAPK14 MAPK12 DDHD1 SEC62 MAPK1 MAPK11 GPAT4 HCK	2.10e-04	391	145	10	CID000003987
Drug	myo-inositol	CHRNA6 MYLK AVPR1A POLR2A AKR1A1 ABHD4 CACNA2D4 MAPK14 KISS1R MAPK12 NISCH MAPK1 MAPK11 DAGLA HCK	2.14e-04	811	145	15	CID000000892
Drug	Ethisterone [434-03-7]; Down 200; 12.8uM; PC3; HT_HG-U133A	CHRNA6 DEAF1 ATP9B SLC5A2 TAOK2 MAPK14 ASTN2	2.21e-04	190	145	7	4340_DN
Drug	SB202190	MAP3K20 FASLG MAPK14 MAPK12 MAPK1 MAPK11	2.21e-04	134	145	6	CID005353940
Drug	C11102	AQP6 MAPK14 MAPK12 MAPK1 MAPK11	2.25e-04	86	145	5	CID000443069
Drug	NK 631	MGAM TAAR6 TAOK2	2.27e-04	19	145	3	CID000004741
Drug	celiprolol	MAPK14 MAPK12 MAPK1 MAPK11	2.28e-04	47	145	4	CID000002663
Drug	Harmol hydrochloride monohydrate [40580-83-4]; Down 200; 15.8uM; MCF7; HT_HG-U133A	PSEN2 POLR2A GAS6 ADGRG1 ADGRL1 FBXO11 MAPK11	2.28e-04	191	145	7	6022_DN
Drug	Nifuroxazide [965-52-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A	GAS6 MAP3K20 ADGRL1 TAOK2 STK11 LSS MAPK11	2.28e-04	191	145	7	2850_DN
Drug	CP-320650-01 [172079-28-6]; Up 200; 10uM; MCF7; HT_HG-U133A	CEL ABHD3 ATP9B SLC5A2 STXBP3 CELSR3 CNTN1	2.28e-04	191	145	7	3905_UP
Drug	Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; HL60; HT_HG-U133A	MAK TCN1 MAN1C1 PAK4 ATP9B TESK1 STK11	2.28e-04	191	145	7	2937_DN
Drug	bovine serum albumin-corticosterone conjugate	MAPK14 MAPK1	2.40e-04	4	145	2	ctd:C439264
Drug	corticosterone-21-hemisuccinate	MAPK14 MAPK1	2.40e-04	4	145	2	ctd:C067957
Drug	3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol	DRD3 MAPK1	2.40e-04	4	145	2	ctd:C062458
Drug	DENSPM	MAPK14 MAPK12 MAPK1 MAPK11	2.47e-04	48	145	4	CID000004282
Drug	PHA-00851261E [724719-49-7]; Up 200; 10uM; MCF7; HT_HG-U133A	ADGRG1 SLC24A3 NPFFR1 GPR161 LRRN3 STOML1 LSS	2.51e-04	194	145	7	3854_UP
Drug	Amphotericin B [1397-89-3]; Down 200; 4.4uM; MCF7; HT_HG-U133A	CDK18 SASH1 ADGRL1 SLC24A3 NPFFR1 TAOK2 STK11	2.51e-04	194	145	7	3303_DN
Drug	Methylergometrine maleate [113-42-8]; Up 200; 8.8uM; MCF7; HT_HG-U133A	SETD1B PIPOX ADGRL1 NPFFR1 TAOK2 LSS DAGLA	2.51e-04	194	145	7	5303_UP
Disease	Parkinson's disease (implicated_via_orthology)	DRD3 TOR2A VPS13C PAK4 ATP13A5 PAK6 AXIN2 MAPK14 PTCH2 MAPK11	4.63e-09	157	141	10	DOID:14330 (implicated_via_orthology)
Disease	mastiha supplement exposure measurement, blood glutathione peroxidase measurement	LMBR1 SLC24A4 LSS	1.06e-06	5	141	3	EFO_0600067, EFO_0600071
Disease	Autism Spectrum Disorders	AVPR1A IL1RAPL1 LRRN3 DDHD1 TET1	5.60e-05	85	141	5	C1510586
Disease	mitogen-activated protein kinase 12 measurement	MAPK12 MAPK11	1.35e-04	4	141	2	EFO_0020576
Disease	Schizophrenia	SOX10 DRD3 HTR1F PSEN2 AVPR1A AKR1A1 SETDB1 MAPK14 TET1 ASTN2 KDR MAPK1 SLC7A10	3.30e-04	883	141	13	C0036341
Disease	colipase measurement	MAPK14 LHFPL5	3.36e-04	6	141	2	EFO_0801485
Disease	MEDULLOBLASTOMA	GPR161 PTCH2	3.36e-04	6	141	2	155255
Disease	Medulloblastoma	GPR161 PTCH2	3.36e-04	6	141	2	cv:C0025149
Disease	Cardiomyopathies, Primary	FASLG MAPK14 MAPK1 MAPK11	3.39e-04	69	141	4	C0033141
Disease	Myocardial Diseases, Secondary	FASLG MAPK14 MAPK1 MAPK11	3.39e-04	69	141	4	C0036529
Disease	amyotrophic lateral sclerosis (is_marker_for)	KEAP1 BPTF KDR	3.56e-04	29	141	3	DOID:332 (is_marker_for)
Disease	endometrial adenocarcinoma (is_implicated_in)	AXIN2 MAPK1	4.69e-04	7	141	2	DOID:2870 (is_implicated_in)
Disease	Cholestasis, Extrahepatic	KEAP1 MAPK14 MAPK1	4.79e-04	32	141	3	C0005398
Disease	Adenocarcinoma of lung (disorder)	KEAP1 STK11 MAPK14 KDR PRKDC EPHA3	4.83e-04	206	141	6	C0152013
Disease	Glioma	GPR161 PTCH2	7.98e-04	9	141	2	cv:C0017638
Disease	Hepatic Insufficiency	KEAP1 MAPK14	7.98e-04	9	141	2	C1306571
Disease	level of Phosphatidylcholine (16:0_22:4) in blood serum	MAP4K4 DAGLA	7.98e-04	9	141	2	OBA_2045078
Disease	medulloblastoma (is_implicated_in)	GPR161 PTCH2	9.95e-04	10	141	2	DOID:0050902 (is_implicated_in)
Disease	osteoarthritis, knee, body mass index	TBX15 TAOK2 ABHD16B	9.97e-04	41	141	3	EFO_0004340, EFO_0004616
Disease	colonic neoplasm	MAP3K20 DDHD1 ASTN2	9.97e-04	41	141	3	EFO_0004288
Disease	high grade glioma (is_marker_for)	SETDB1 KDR CNTN2	1.07e-03	42	141	3	DOID:3070 (is_marker_for)
Disease	Gastrointestinal Diseases	MYLK KEAP1	1.45e-03	12	141	2	C0017178
Disease	Functional Gastrointestinal Disorders	MYLK KEAP1	1.45e-03	12	141	2	C0559031
Disease	Cholera Infantum	MYLK KEAP1	1.45e-03	12	141	2	C1565321
Disease	level of Phosphatidylinositol (18:0_20:3) in blood serum	MBOAT7 DAGLA	1.45e-03	12	141	2	OBA_2045157
Disease	Cardiomyopathy, Dilated	PSEN2 FASLG AXIN2	1.58e-03	48	141	3	C0007193
Disease	ascorbic acid 2-sulfate measurement	DEAF1 TAOK2	1.71e-03	13	141	2	EFO_0800169
Disease	Skin Abnormalities	AP1B1 LSS	1.71e-03	13	141	2	C0037268
Disease	gallbladder cancer (is_implicated_in)	KEAP1 AXIN2	1.71e-03	13	141	2	DOID:3121 (is_implicated_in)
Disease	Cardiomyopathy, Familial Idiopathic	PSEN2 FASLG AXIN2	1.78e-03	50	141	3	C1449563
Disease	1-stearoyl-2-dihomo-linolenoyl-GPI (18:0/20:3n3 or 6) measurement	MBOAT7 DAGLA	1.99e-03	14	141	2	EFO_0022085
Disease	pancreatic cancer (is_implicated_in)	FASLG STK11 KDR EPHA3	2.08e-03	112	141	4	DOID:1793 (is_implicated_in)
Disease	Metastatic melanoma	PASK STK11 PRKDC	2.22e-03	54	141	3	C0278883
Disease	Hepatitis	KEAP1 FASLG	2.29e-03	15	141	2	C0019158
Disease	Congenital total cataract	CRYGB LSS	2.60e-03	16	141	2	C0266539
Disease	central nervous system disease (implicated_via_orthology)	TAOK2 TAOK1	2.60e-03	16	141	2	DOID:331 (implicated_via_orthology)
Disease	fasting blood glucose measurement	PDE6C STARD10 ATP9B PAK6 SLC24A4 DAGLA	2.63e-03	287	141	6	EFO_0004465
Disease	post-traumatic stress disorder	BPTF NUP133 SLC4A5 ZMYM4 DPY19L2P1	2.92e-03	202	141	5	EFO_0001358
Disease	body weight	MGAM C2orf69 CACUL1 HTR1F VPS13C ATP13A5 SNUPN PAK6 AXIN2 ABHD17C BPTF SLC24A4 FNIP1 ASTN2	2.93e-03	1261	141	14	EFO_0004338
Disease	sphingomyelin 14:0 measurement	PAK6 NID1	2.94e-03	17	141	2	EFO_0010390
Disease	lysophosphatidylcholine measurement	MGAM ABHD3 DAGLA	3.29e-03	62	141	3	EFO_0010224
Disease	Congenital Fiber Type Disproportion	MAP3K20 MTM1	3.30e-03	18	141	2	C0546264
Disease	hepatocellular carcinoma (is_marker_for)	PLOD3 FBXO11 FASLG AXIN2 TET1 KDR	3.33e-03	301	141	6	DOID:684 (is_marker_for)
Disease	transitional cell carcinoma (is_marker_for)	FASLG KISS1R KDR	3.44e-03	63	141	3	DOID:2671 (is_marker_for)
Disease	Cardiomyopathies	FASLG MAPK14 MAPK1 MAPK11	3.56e-03	130	141	4	C0878544
Disease	Global developmental delay	POLR2A AP1B1 TAOK1 LSS	3.87e-03	133	141	4	C0557874
Disease	myocardial infarction (implicated_via_orthology)	AVPR1A KDR MAPK1	3.92e-03	66	141	3	DOID:5844 (implicated_via_orthology)
Disease	schizophrenia (implicated_via_orthology)	AVPR1A LRRN3 ASTN1	4.27e-03	68	141	3	DOID:5419 (implicated_via_orthology)
Disease	Deep Vein Thrombosis	F8 KDR	4.49e-03	21	141	2	C0149871
Disease	Venous Thrombosis	F8 KDR	4.49e-03	21	141	2	C0042487
Disease	Stomach Carcinoma	AXIN2 STK11	4.49e-03	21	141	2	C0699791
Disease	hepatitis B (is_marker_for)	FASLG MAP4K4	4.49e-03	21	141	2	DOID:2043 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
YRGMELIPTITSWRV	ATP13A5	1101	Q4VNC0
VTPYQVRDPMRSWIG	C2orf69	331	Q8N8R5
VMPFSIVYIVRESWI	HTR1F	76	P30939
LGYFSWVMPVSVALS	SLC7A10	311	Q9NS82
VLLGSTEYSTPIDMW	CDK18	311	Q07002
VMPWIPYRTDTLTEY	ADGRL1	176	O94910
VQPSYRSALMWFGVI	AKTIP	96	Q9H8T0
ELVVSYPFDMTRTPW	CPXM1	501	Q96SM3
WRLLTPGDYMVTASA	CPXM1	661	Q96SM3
IGFLEGIWPRQSTYM	ABHD3	376	Q8WU67
VPITMIYGSDTWIDT	ABHD4	281	Q8TB40
IWEDETVLPMYEGRI	AXIN2	821	Q9Y2T1
EPEARAAMIWIVGEY	AP1B1	441	Q10567
VGITMIDLYPRDSWN	AMZ2	171	Q86W34
RDLPVMIWIYGGAFL	CEL	116	P19835
STLYFIDGMTWPEVL	BPTF	316	Q12830
IDGMTWPEVLRVYCE	BPTF	321	Q12830
RIITRFAPMLVPYIW	ECD	41	O95905
RFTYTLGEGMWLPLS	ASTN1	541	O14525
EEVRPAGMVWYSILK	ASTN2	1301	O75129
LGRWLVYPGSVSLMT	ABHD16B	106	Q9H3Z7
YTLRPEWVQMAPTLF	CACUL1	291	Q86Y37
MVWLVTIIGYTLGIP	SLC24A4	471	Q8NFF2
GYVLPSHVTEEMLWE	QRICH1	596	Q2TAL8
AWPEKGMRRVYTTVL	NPFFR1	206	Q9GZQ6
GLPTTWGTRYIMVSF	PLOD3	721	O60568
EYVATRWYRAPEIML	MAPK1	186	P28482
MVATREGSIRYWPSL	NUP133	176	Q8WUM0
EVIIAAWYRTFIGIM	DPY19L2P1	191	Q6NXN4
LQWGEMPTSVAYIRS	MAP4K4	1156	O95819
GPELEMWSLGVTLYT	PASK	1181	Q96RG2
LVGTPYWMAPEVISR	PAK6	561	Q9NQU5
GYVATRWYRAPEIML	MAPK11	181	Q15759
EPIGYATDMWSIGVI	MYLK	1636	Q15746
PEEVIWEALSVMGVY	MAGEA9	216	P43362
LPMPIDVVYTWVNGT	GNPTAB	71	Q3T906
TELIGRPAMIPYWAL	MGAM2	1186	Q2M2H8
GYVATRWYRAPEIML	MAPK14	181	Q16539
WVILRPGRYICSEMD	GLB1L3	156	Q8NCI6
SAWERNLVYPAVMVL	LMBR1	286	Q8WVP7
PIYAVTVSMGLWAFI	APH1A	216	Q96BI3
TYWAPLGFVLAVTMT	ATP9B	181	O43861
TELIGRPVMVPYWSL	MGAM	2126	O43451
LVYPDGWDSSEVRRM	LHFPL5	146	Q8TAF8
PVIKRTWSSEEMVYP	FAT2	4161	Q9NYQ8
VMTPNYVVRRGWSIF	IL1RAPL1	476	Q9NZN1
PVEVLTRWMYTVRKG	PDE6C	541	P51160
MVYWTDITEPSIGRA	NID1	991	P14543
MLSPTFVLWEVGYPL	FAM205A	1	Q6ZU69
TINMLVRWYVDGPAS	LSS	341	P48449
SFWTTMPLVGLGDYV	OPN5	161	Q6U736
MSVDRWYVTVFPLRA	KISS1R	136	Q969F8
MSPEEWTYLVVLLIS	MBOAT7	1	Q96N66
MGVYAPTLLIVVLSW	GLRB	271	P48167
SVYWHVIGMGTTPEV	F8	271	P00451
WMVTIIGYTLGIPDV	SLC24A3	496	Q9HC58
LLMWSPVIAPGETVY	IL20RB	51	Q6UXL0
YVPNMVVWEHTFTPR	NCKAP1	691	Q9Y2A7
AYIQPWRFRVEMIKG	CCDC105	66	Q8IYK2
WEEFVYLRSRNPLMV	CPT1C	236	Q8TCG5
RWDPMEYDGIETLRV	CHRNA6	96	Q15825
WSFGILLMEIVTYGR	HCK	441	P08631
MPRYTVHVRGEWLAV	HAL	1	P42357
EALETSVGYAWLPLM	DOCK10	781	Q96BY6
IVCSVWYLPPMTREA	GPAT4	381	Q86UL3
LYVFFGVGSVMRWPT	AQP6	36	Q13520
ELSEPRSWLYLEEMV	DEAF1	446	O75398
TDEWIYIESPITMIG	FBXO11	296	Q86XK2
VVTAPMEAYWTALAL	CACNA2D4	731	Q7Z3S7
NLYTMPRIGEPVWLT	FNIP1	406	Q8TF40
LERIFWIPIVREYVM	DGAT2L6	141	Q6ZPD8
DYMRTPLDVGTESTW	GAS6	491	Q14393
PPVWESVTYGMVLQR	HAP1	186	P54257
LIPWMEYEFRVVATN	CNTN1	671	Q12860
AMYERCPRAVEPLWV	ABHD17C	286	Q6PCB6
RTPEGVIYPSMCWIR	ADGRG1	551	Q9Y653
QVLGLTPWMDYEFRV	CNTN2	671	Q02246
IRVESGCWMIYERPN	CRYGB	36	P07316
GIVLWEVMSYGERPY	EPHA3	811	P29320
LIFDLGDPVRWEYML	DRC7	361	Q8IY82
LIRAVTWMDNPIEVY	ERVK-21	111	P61565
VYSSPIDVWAVGSIM	MAK	176	P20794
SYGVVLWEMLTREVP	MAP3K20	191	Q9NYL2
LRPEVVESYMYLWRQ	MAN1C1	521	Q9NR34
IIWLSMRGGILYTEP	DAGLA	76	Q9Y4D2
EWYPSLATMQESLRV	GADD45GIP1	91	Q8TAE8
VTWGPYMVVIASEAL	GPR161	281	Q8N6U8
RYDVETETWTFVAPM	KEAP1	536	Q14145
VITYDIMTGWNPVRL	DDHD1	541	Q8NEL9
PTSWVYLTAAVMERL	SDR42E2	306	A6NKP2
MAVSVPWYLGLAFRT	CELSR3	1781	Q9NYQ7
WVYNRSVFPSTIVME	SLC22A20P	111	A6NK97
YMREVTTIDPRWLVE	DHX8	1161	Q14562
LVMPWVVYLEVTGGV	DRD3	81	P35462
VGTPYWMAPELISRL	PAK4	476	O96013
GTNYLMPWDIVIRTR	SMG8	791	Q8ND04
PMLGITGSERDYQLW	ARHGAP20	231	Q9P2F6
TITIELWGYEETGMP	SUSD2	191	Q9UGT4
ITLRSWLPMGADYII	STARD10	131	Q9Y365
MEVLRPFLGSSWVVY	TOR2A	171	Q8N2E6
GVTVVAFMISWLPYS	TAAR6	261	Q96RI8
ISIIGIAMAVLGYWP	TMEM200A	71	Q86VY9
EIRPWFTPRSIYMEA	LRRN3	36	Q9H3W5
IPPELFYMGLTVWVS	PTCH2	851	Q9Y6C5
METYAFWRPPVRTLT	TBX15	316	Q96SF7
CTRELSWTPMGYVVR	SECISBP2	291	Q96T21
SFVGTPYWMAPEVIL	TAOK1	181	Q7L7X3
SFVGTPYWMAPEVIL	TAOK2	181	Q9UL54
LYSGWEPVIIAMAIS	SLC41A1	316	Q8IVJ1
PRSEFEEMTILYDIW	SETD1B	1671	Q9UPS6
RWRSMTVVPYLEDLH	STK11	331	Q15831
TPLVGWLRPYMVSDV	SNUPN	271	O95149
WLRPYMVSDVLGVAV	SNUPN	276	O95149
SDMIRNWSYLGVPIV	STXBP3	436	O00186
EWIYRGSTRLEPMFS	SETDB1	386	Q15047
VWDGIPLPMADRLYT	TET1	1521	Q8NFU7
WRYIVPMLTVDGKRV	AKR1A1	296	P14550
RAPIDWIEEYTTGMA	ALG2	156	Q9H553
MEVLRPFLGSSWVVY	TOR2A	171	Q5JU69
AIVPLWASMGNYITR	UNC93B1	171	Q9H1C4
VLYPVASMRHLELWV	MTM1	521	Q13496
TLFPLWPAEMRVGVY	SEC62	211	Q99442
WLFAPVYLTAGVITM	SLC5A2	111	P31639
WFALKIVPTYERMIV	STOML1	76	Q9UBI4
VLARAPVMDTWFYIT	SPIN4	141	Q56A73
RYARPEWMIVTVLPV	POLR2A	241	P24928
ILEWHYVVRGPEMTP	UBE2J2	41	Q8N2K1
LMWSSVVFYQTPGLE	NISCH	1161	Q9Y2I1
SGYDWTLVPMPVRVN	SOX10	81	P56693
TMEERSWGPYITCIQ	TCN1	376	P20061
VSWYTLMEGQEPIAR	USP15	101	Q9Y4E8
EPIFPALIYSSAMVW	PSEN2	286	P49810
SVSDWLISIGLPMYA	SASH1	1181	O94885
FMGLPWYVAATVISI	SLC4A5	886	Q9BY07
GSRMVLSVFSPYWLI	VPS13C	2761	Q709C8
AVVGSPYWMAPEVLR	TESK1	216	Q15569
YILRPVAFLMGVAWE	SLC28A1	466	O00337
RSMPLEWEDTYGIVL	FASLG	156	P48023
YVTWMTGGIFVAPVV	AVPR1A	216	P37288
VGAPLWAVMDVYGTT	NEURL3	151	Q96EH8
YSVVPMTSRLGLIEW	PRKDC	3791	P78527
AWYSVGALMISVPAL	ZFYVE27	91	Q5T4F4
TLRINVCYWREMVPG	PIPOX	221	Q9P0Z9
WMAPETIFDRVYTIQ	KDR	1071	P35968
TNVIMWDPYTGERLR	WSB2	261	Q9NYS7
IYSVRVGSPWIDQMT	PRSS50	161	Q9UI38
WEPTILPNGYMFSRI	ZMYM4	1346	Q5VZL5
WVEVMRAATFTYSPL	TEX38	51	Q6PEX7
IGYLQFRLVELVWMP	PLPP7	246	Q8NBV4
FMPDPSSEWLYRVTV	XKR8	251	Q9H6D3
EMTGYVVTRWYRAPE	MAPK12	181	P53778
PWTRYVDIALRTDMS	NAT8B	81	Q9UHF3
RELYIRWLEVAAFMP	MYORG	571	Q6NSJ0