Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RGPD2 RANBP2

1.03e-0520433GO:0061665
GeneOntologyMolecularFunctionSUMO transferase activity

RGPD4 RGPD2 RANBP2

6.32e-0536433GO:0019789
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

RGPD4 RGPD2 RANBP2

1.70e-0450433GO:0003755
GeneOntologyMolecularFunctioncis-trans isomerase activity

RGPD4 RGPD2 RANBP2

2.02e-0453433GO:0016859
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RGPD2 RANBP2

7.03e-079433GO:0033133
GeneOntologyBiologicalProcessmulti-pass transmembrane protein insertion into ER membrane

NOMO2 NOMO3 NOMO1

7.03e-079433GO:0160063
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD4 RGPD2 RANBP2

1.00e-0610433GO:1903301
GeneOntologyBiologicalProcessprotein localization to organelle

RGPD4 TXNIP FSIP2 RGPD2 EPS15 RANBP2 LRRC7 NOMO2 NOMO3 NOMO1 PYHIN1 VPS13A

1.51e-0610914312GO:0033365
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD4 RGPD2 RANBP2

2.38e-0613433GO:0033131
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD4 RGPD2 RANBP2

3.02e-0614433GO:1903299
GeneOntologyBiologicalProcessprotein insertion into membrane

EGFR NOMO2 NOMO3 NOMO1

3.52e-0650434GO:0051205
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD4 RGPD2 RANBP2

9.39e-0620433GO:0006607
GeneOntologyBiologicalProcesslateral mesoderm development

TEAD1 NOMO3 NOMO1

9.39e-0620433GO:0048368
GeneOntologyBiologicalProcesslocalization within membrane

EPS15 STAC2 LRRC7 TNFAIP6 EGFR NOMO2 NOMO3 STAC3 NOMO1

3.21e-05798439GO:0051668
GeneOntologyBiologicalProcessprotein insertion into ER membrane

NOMO2 NOMO3 NOMO1

3.64e-0531433GO:0045048
GeneOntologyBiologicalProcessprotein peptidyl-prolyl isomerization

RGPD4 RGPD2 RANBP2

6.77e-0538433GO:0000413
GeneOntologyBiologicalProcessestablishment of protein localization to organelle

RGPD4 TXNIP RGPD2 EPS15 RANBP2 LRRC7 VPS13A

8.59e-05515437GO:0072594
GeneOntologyBiologicalProcessnegative regulation of nodal signaling pathway

NOMO3 NOMO1

8.86e-057432GO:1900108
GeneOntologyBiologicalProcessprotein localization to membrane

STAC2 LRRC7 TNFAIP6 EGFR NOMO2 NOMO3 STAC3 NOMO1

9.00e-05705438GO:0072657
GeneOntologyBiologicalProcesscirculatory system development

GBX2 GJA5 HHIP CHD7 FBN1 TEAD1 NFATC1 EGFR DSG2 ENPEP GPX1

1.34e-0414424311GO:0072359
GeneOntologyBiologicalProcessregulation of nodal signaling pathway

NOMO3 NOMO1

1.51e-049432GO:1900107
GeneOntologyBiologicalProcesspositive regulation of voltage-gated calcium channel activity

STAC2 STAC3

1.51e-049432GO:1901387
GeneOntologyBiologicalProcesspositive regulation of protein localization to membrane

STAC2 TNFAIP6 EGFR STAC3

1.54e-04130434GO:1905477
GeneOntologyBiologicalProcesspositive regulation of kinase activity

RGPD4 RGPD2 RANBP2 FBN1 TEAD1 EGFR

1.82e-04405436GO:0033674
GeneOntologyBiologicalProcessdetermination of left/right asymmetry in lateral mesoderm

NOMO3 NOMO1

1.89e-0410432GO:0003140
GeneOntologyBiologicalProcesspeptidyl-proline modification

RGPD4 RGPD2 RANBP2

1.94e-0454433GO:0018208
GeneOntologyBiologicalProcesstransition between fast and slow fiber

TEAD1 NFATC1

3.26e-0413432GO:0014883
GeneOntologyBiologicalProcessregulation of protein localization

EPS15 GJA5 STAC2 FBN1 TNFAIP6 RALGAPA2 EGFR STAC3 PYHIN1

3.37e-041087439GO:0032880
GeneOntologyBiologicalProcessresponse to calcium ion

TXNIP ADGRV1 NFATC1 EGFR

3.48e-04161434GO:0051592
GeneOntologyBiologicalProcesspositive regulation of protein localization to plasma membrane

STAC2 EGFR STAC3

4.19e-0470433GO:1903078
GeneOntologyBiologicalProcesstube morphogenesis

GBX2 GJA5 HHIP CHD7 TEAD1 NFATC1 EGFR ENPEP GPX1

4.34e-041125439GO:0035239
GeneOntologyBiologicalProcessregulation of gluconeogenesis

RGPD4 RGPD2 RANBP2

4.37e-0471433GO:0006111
GeneOntologyBiologicalProcessbundle of His cell to Purkinje myocyte communication

GJA5 DSG2

4.38e-0415432GO:0086069
GeneOntologyBiologicalProcessvasodilation

GJA5 EGFR GPX1

4.55e-0472433GO:0042311
GeneOntologyBiologicalProcesstube development

GBX2 GJA5 HHIP CHD7 FBN1 TEAD1 NFATC1 EGFR ENPEP GPX1

4.94e-0414024310GO:0035295
GeneOntologyBiologicalProcesspositive regulation of transferase activity

RGPD4 RGPD2 RANBP2 FBN1 TEAD1 EGFR

5.04e-04490436GO:0051347
GeneOntologyBiologicalProcessestablishment of protein localization to membrane

LRRC7 EGFR NOMO2 NOMO3 NOMO1

5.10e-04319435GO:0090150
GeneOntologyBiologicalProcesspositive regulation of DNA damage response, signal transduction by p53 class mediator

HIC1 PYHIN1

5.66e-0417432GO:0043517
GeneOntologyBiologicalProcesspositive regulation of molecular function

RGPD4 RGPD2 STAC2 RANBP2 FBN1 TEAD1 RALGAPA2 EGFR STAC3 PYHIN1

5.77e-0414304310GO:0044093
GeneOntologyBiologicalProcessGolgi to endosome transport

EPS15 VPS13A

6.36e-0418432GO:0006895
GeneOntologyBiologicalProcesspositive regulation of protein localization to cell periphery

STAC2 EGFR STAC3

6.66e-0482433GO:1904377
GeneOntologyBiologicalProcessprotein import into nucleus

RGPD4 TXNIP RGPD2 RANBP2

7.16e-04195434GO:0006606
GeneOntologyBiologicalProcessregulation of cellular localization

EPS15 GJA5 STAC2 FBN1 TNFAIP6 RALGAPA2 EGFR STAC3 PYHIN1

7.45e-041212439GO:0060341
GeneOntologyBiologicalProcessintracellular protein transport

SCFD2 RGPD4 TXNIP RGPD2 RANBP2 LRRC7 VPS13A

7.77e-04740437GO:0006886
GeneOntologyBiologicalProcesspulmonary valve morphogenesis

GJA5 NFATC1

7.88e-0420432GO:0003184
GeneOntologyBiologicalProcessregulation of skeletal muscle adaptation

TEAD1 NFATC1

7.88e-0420432GO:0014733
GeneOntologyBiologicalProcessimport into nucleus

RGPD4 TXNIP RGPD2 RANBP2

8.02e-04201434GO:0051170
GeneOntologyBiologicalProcesscardiac septum morphogenesis

GJA5 CHD7 NFATC1

8.46e-0489433GO:0060411
GeneOntologyBiologicalProcessnegative regulation of activin receptor signaling pathway

NOMO3 NOMO1

8.69e-0421432GO:0032926
GeneOntologyBiologicalProcessheart development

GJA5 CHD7 FBN1 TEAD1 NFATC1 EGFR DSG2

8.88e-04757437GO:0007507
GeneOntologyBiologicalProcessmuscle system process

GJA5 STAC2 TEAD1 NFATC1 DSG2 STAC3

8.96e-04547436GO:0003012
GeneOntologyBiologicalProcessprotein localization to nucleus

RGPD4 TXNIP RGPD2 RANBP2 PYHIN1

9.02e-04362435GO:0034504
GeneOntologyBiologicalProcessmesenchyme development

GBX2 TEAD1 NFATC1 NOMO3 NOMO1

1.02e-03372435GO:0060485
GeneOntologyBiologicalProcessregulation of systemic arterial blood pressure by circulatory renin-angiotensin

GJA5 ENPEP

1.04e-0323432GO:0001991
GeneOntologyBiologicalProcessstriated muscle contraction

GJA5 STAC2 DSG2 STAC3

1.07e-03217434GO:0006941
GeneOntologyBiologicalProcessnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

FBN1 TNFAIP6 NOMO3 NOMO1

1.08e-03218434GO:0090101
GeneOntologyBiologicalProcesspulmonary valve development

GJA5 NFATC1

1.14e-0324432GO:0003177
GeneOntologyBiologicalProcessnodal signaling pathway

NOMO3 NOMO1

1.34e-0326432GO:0038092
GeneOntologyBiologicalProcessendoplasmic reticulum organization

NOMO2 NOMO3 NOMO1

1.44e-03107433GO:0007029
GeneOntologyBiologicalProcessregulation of protein localization to membrane

STAC2 TNFAIP6 EGFR STAC3

1.48e-03237434GO:1905475
GeneOntologyBiologicalProcessgluconeogenesis

RGPD4 RGPD2 RANBP2

1.60e-03111433GO:0006094
GeneOntologyBiologicalProcessglucose metabolic process

RGPD4 RGPD2 RANBP2 FBN1

1.64e-03244434GO:0006006
GeneOntologyBiologicalProcesshexose biosynthetic process

RGPD4 RGPD2 RANBP2

1.77e-03115433GO:0019319
GeneOntologyBiologicalProcessregulation of cardiac muscle cell action potential

GJA5 DSG2

1.78e-0330432GO:0098901
GeneOntologyBiologicalProcessregulation of activin receptor signaling pathway

NOMO3 NOMO1

2.02e-0332432GO:0032925
GeneOntologyBiologicalProcessskeletal muscle adaptation

TEAD1 NFATC1

2.02e-0332432GO:0043501
GeneOntologyBiologicalProcessmonosaccharide biosynthetic process

RGPD4 RGPD2 RANBP2

2.05e-03121433GO:0046364
GeneOntologyBiologicalProcessblood circulation

GJA5 CHD7 EGFR DSG2 ENPEP GPX1

2.13e-03648436GO:0008015
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RGPD2 RANBP2

4.51e-078433GO:1990723
GeneOntologyCellularComponentmulti-pass translocon complex

NOMO2 NOMO3 NOMO1

6.75e-079433GO:0160064
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RGPD2 RANBP2

9.63e-0710433GO:0044614
GeneOntologyCellularComponentinclusion body

RGPD4 RGPD2 EPS15 RANBP2 GPX1

1.12e-0690435GO:0016234
GeneOntologyCellularComponentannulate lamellae

RGPD4 RGPD2 RANBP2

2.90e-0614433GO:0005642
GeneOntologyCellularComponentER membrane insertion complex

NOMO2 NOMO3 NOMO1

2.90e-0614433GO:0072379
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD4 RGPD2 RANBP2

6.47e-0618433GO:0044615
GeneOntologyCellularComponentnuclear inclusion body

RGPD4 RGPD2 RANBP2

9.02e-0620433GO:0042405
GeneOntologyCellularComponentSUMO ligase complex

RGPD4 RGPD2 RANBP2

1.05e-0521433GO:0106068
GeneOntologyCellularComponentnuclear pore

RGPD4 RGPD2 RANBP2

1.17e-03101433GO:0005643
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

RGPD4 RGPD2 RANBP2 TMEM214 EGFR NOMO2 NOMO3 NOMO1 VPS13A

1.29e-031327439GO:0042175
GeneOntologyCellularComponentcell projection membrane

EPS15 HHIP ADGRV1 EGFR ENPEP

1.84e-03431435GO:0031253
MousePhenoincreased hepatocellular carcinoma incidence

RGPD4 TXNIP RGPD2 RANBP2 HIC1

7.87e-0770355MP:0003331
MousePhenolong snout

CHD7 EGFR

6.09e-062352MP:0000446
MousePhenoincreased hepatobiliary system tumor incidence

RGPD4 TXNIP RGPD2 RANBP2 HIC1

7.74e-06111355MP:0010297
MousePhenoincreased liver tumor incidence

RGPD4 TXNIP RGPD2 RANBP2 HIC1

7.74e-06111355MP:0008019
MousePhenoelevated level of mitotic sister chromatid exchange

RGPD4 RGPD2 RANBP2

7.87e-0616353MP:0003701
MousePhenoabnormal morula morphology

RGPD4 RGPD2 RANBP2

3.59e-0526353MP:0012058
MousePhenocardiac valve regurgitation

FBN1 NFATC1 EGFR

3.59e-0526353MP:0009384
MousePhenoincreased lung carcinoma incidence

RGPD4 RGPD2 RANBP2 HIC1

4.12e-0578354MP:0008714
MousePhenoabnormal heart valve physiology

FBN1 NFATC1 EGFR

5.57e-0530353MP:0011926
MousePhenodecreased tumor latency

RGPD4 RGPD2 RANBP2

5.57e-0530353MP:0010308
MousePhenoabsent cochlear ganglion

GBX2 ADGRV1

6.06e-055352MP:0003146
MousePhenofailure of blastocyst formation

RGPD4 RGPD2 RANBP2

6.16e-0531353MP:0012129
MousePhenoabnormal tumor latency

RGPD4 RGPD2 RANBP2

8.16e-0534353MP:0010307
MousePhenoenlarged epididymis

RGPD4 RGPD2 RANBP2 GPX1

1.05e-0499354MP:0004931
MousePhenoabnormal heart ventricle morphology

TXNIP GBX2 GJA5 CHD7 FBN1 TEAD1 NFATC1 EGFR DSG2

1.08e-04793359MP:0005294
MousePhenoabnormal susceptibility to hearing loss

CHD7 ADGRV1 GPX1

1.14e-0438353MP:0006334
MousePhenoincreased sarcoma incidence

RGPD4 RGPD2 RANBP2 HIC1

1.18e-04102354MP:0002032
MousePhenoincreased carcinoma incidence

RGPD4 TXNIP RGPD2 RANBP2 HIC1

1.22e-04197355MP:0002038
MousePhenoabnormal blastocyst formation

RGPD4 RGPD2 RANBP2

1.24e-0439353MP:0012128
MousePhenoabnormal costal cartilage morphology

FBN1 STAC3

1.27e-047352MP:0006432
MousePhenoincreased respiratory system tumor incidence

RGPD4 RGPD2 RANBP2 HIC1

1.42e-04107354MP:0010298
MousePhenoincreased lung tumor incidence

RGPD4 RGPD2 RANBP2 HIC1

1.42e-04107354MP:0008014
MousePhenoabnormal mitral valve morphology

GJA5 FBN1 NFATC1

1.44e-0441353MP:0000286
MousePhenoabnormal sensory ganglion morphology

GBX2 CHD7 ADGRV1 EGFR GPX1

2.08e-04221355MP:0000960
MousePhenoabsent posterior semicircular canal

GBX2 CHD7

2.17e-049352MP:0003163
MousePhenoabnormal aorta morphology

GBX2 GJA5 CHD7 FBN1 EGFR

2.26e-04225355MP:0000272
MousePhenoincreased malignant tumor incidence

RGPD4 TXNIP RGPD2 RANBP2 HIC1

2.88e-04237355MP:0002018
MousePhenoabnormal common crus morphology

GBX2 CHD7

3.30e-0411352MP:0004922
MousePhenofusion of glossopharyngeal and vagus nerve

GBX2 CHD7

3.30e-0411352MP:0004568
MousePhenoabnormal thoracic aorta morphology

GBX2 GJA5 CHD7 FBN1

3.36e-04134354MP:0010468
MousePhenoincreased organ/body region tumor incidence

RGPD4 TXNIP RGPD2 RANBP2 HIC1 RALGAPA2

3.97e-04395356MP:0010274
MousePhenoincreased incidence of tumors by chemical induction

RGPD4 RGPD2 RANBP2 RALGAPA2

4.07e-04141354MP:0004499
MousePhenoabnormal organ/body region tumor incidence

RGPD4 TXNIP RGPD2 RANBP2 HIC1 RALGAPA2

4.30e-04401356MP:0013152
MousePhenoabnormal pulmonary alveolar duct morphology

HHIP FBN1

4.67e-0413352MP:0002271
MousePhenoabsent lateral semicircular canal

GBX2 CHD7

4.67e-0413352MP:0003161
MousePhenoaneuploidy

RGPD4 RGPD2 RANBP2

4.68e-0461353MP:0004024
MousePhenoabnormal lung morphology

RGPD4 RGPD2 HHIP RANBP2 HIC1 FBN1 EGFR STAC3

4.96e-04767358MP:0001175
MousePhenosmall otic vesicle

GBX2 CHD7

6.27e-0415352MP:0004310
MousePhenoabnormal mitral valve cusp morphology

FBN1 NFATC1

6.27e-0415352MP:0010614
MousePhenodecreased susceptibility to diet-induced obesity

RGPD4 RGPD2 RANBP2 FBN1

6.56e-04160354MP:0005659
MousePhenoabnormal atrioventricular valve morphology

GJA5 FBN1 NFATC1

6.73e-0469353MP:0002745
MousePhenoabnormal heart valve morphology

GJA5 FBN1 NFATC1 EGFR

7.04e-04163354MP:0000285
MousePhenoabnormal superior semicircular canal morphology

GBX2 CHD7

7.15e-0416352MP:0003069
MousePhenodisorganized pancreatic islets

HHIP EGFR

7.15e-0416352MP:0009254
MousePhenointerrupted aortic arch, type b

GBX2 CHD7

7.15e-0416352MP:0011659
MousePhenoabnormal respiratory system morphology

RGPD4 RGPD2 HHIP RANBP2 HIC1 CHD7 FBN1 EGFR STAC3

7.42e-041027359MP:0002132
MousePhenoabnormal epididymis size

RGPD4 RGPD2 RANBP2 GPX1

7.54e-04166354MP:0004926
MousePhenosmall middle ear ossicles

GBX2 CHD7

8.09e-0417352MP:0030123
MousePhenoabnormal fourth pharyngeal arch artery morphology

GBX2 CHD7

8.09e-0417352MP:0006354
MousePhenoabnormal heart atrium and ventricle connection

GJA5 FBN1 NFATC1

8.58e-0475353MP:0010435
MousePhenoincreased incidence of induced tumors

RGPD4 RGPD2 RANBP2 RALGAPA2

8.79e-04173354MP:0002021
MousePhenoabnormal atrioventricular cushion morphology

GJA5 CHD7 NFATC1

8.92e-0476353MP:0000297
MousePhenoabnormal systemic artery morphology

GBX2 GJA5 CHD7 FBN1 EGFR

8.94e-04304355MP:0011655
MousePhenosemilunar valve regurgitation

NFATC1 EGFR

9.09e-0418352MP:0006049
MousePhenodecreased atrioventricular cushion size

CHD7 NFATC1

9.09e-0418352MP:0000301
MousePhenoabnormal cranial ganglia morphology

GBX2 CHD7 ADGRV1 GPX1

9.18e-04175354MP:0001081
MousePhenoabnormal ear morphology

GBX2 HIC1 CHD7 ADGRV1 EGFR GPX1

9.91e-04470356MP:0002102
MousePhenoabnormal fetal atrioventricular canal morphology

GJA5 CHD7 NFATC1

1.07e-0381353MP:0006107
MousePhenoabnormal posterior semicircular canal morphology

GBX2 CHD7

1.12e-0320352MP:0002858
MousePhenodecreased susceptibility to weight gain

RGPD4 RGPD2 RANBP2 FBN1

1.15e-03186354MP:0010182
MousePhenodecreased cornea thickness

TEAD1 EGFR

1.24e-0321352MP:0005543
MousePhenoabnormal lateral semicircular canal morphology

GBX2 CHD7

1.24e-0321352MP:0000037
MousePhenoabnormal otic capsule morphology

GBX2 CHD7

1.24e-0321352MP:0000039
MousePhenoabnormal chromosome number

RGPD4 RGPD2 RANBP2

1.28e-0386353MP:0004023
MousePhenoabnormal innervation

GBX2 CHD7 EGFR STAC3

1.32e-03193354MP:0002184
MousePhenoabnormal glossopharyngeal nerve morphology

GBX2 CHD7

1.36e-0322352MP:0001073
MousePhenoabnormal cochlear ganglion morphology

GBX2 ADGRV1 GPX1

1.36e-0388353MP:0002855
MousePhenocardiac hypertrophy

FBN1 NFATC1 EGFR DSG2

1.40e-03196354MP:0001625
MousePhenoincreased energy expenditure

RGPD4 RGPD2 RANBP2 FBN1

1.40e-03196354MP:0004889
MousePhenoabnormal fourth pharyngeal arch morphology

GBX2 CHD7

1.49e-0323352MP:0006340
MousePhenoabnormal P wave

GJA5 DSG2

1.62e-0324352MP:0004070
MousePhenoabnormal cochlear sensory epithelium morphology

GBX2 CHD7 ADGRV1 GPX1

1.71e-03207354MP:0003308
MousePhenoabnormal cerebellum development

GBX2 CHD7 EGFR

1.75e-0396353MP:0000854
MousePhenoabnormal maternal decidual layer morphology

FBN1 EGFR

1.76e-0325352MP:0004256
MousePhenoembryonic lethality between implantation and somite formation, incomplete penetrance

EGFR DSG2

1.76e-0325352MP:0011106
MousePhenoabnormal organ of Corti morphology

GBX2 CHD7 ADGRV1 GPX1

1.77e-03209354MP:0000042
MousePhenoincreased tumor incidence

RGPD4 TXNIP RGPD2 RANBP2 HIC1 RALGAPA2

1.84e-03530356MP:0002020
MousePhenoprimary atelectasis

HHIP STAC3

2.06e-0327352MP:0010819
MousePhenoabnormal heart left ventricle morphology

TXNIP FBN1 NFATC1 EGFR DSG2

2.11e-03369355MP:0003921
MousePhenoabnormal crista ampullaris morphology

GBX2 CHD7

2.21e-0328352MP:0004249
MousePhenoabnormal cochlear outer hair cell physiology

CHD7 ADGRV1

2.21e-0328352MP:0004434
MousePhenoabnormal vagus nerve morphology

GBX2 CHD7

2.37e-0329352MP:0001074
MousePhenodecreased heart ventricle muscle contractility

TXNIP EGFR DSG2

2.39e-03107353MP:0005598
MousePhenofailure of blastocyst to hatch from the zona pellucida

RGPD4 RGPD2 RANBP2

2.39e-03107353MP:0003694
MousePhenoincreased classified tumor incidence

RGPD4 TXNIP RGPD2 RANBP2 HIC1

2.43e-03381355MP:0010273
MousePhenoabnormal eye electrophysiology

RGPD4 RGPD2 RANBP2 ADGRV1

2.43e-03228354MP:0005551
MousePhenoatelectasis

HHIP EGFR STAC3

2.45e-03108353MP:0001177
DomainDUF2012

NOMO2 NOMO3 NOMO1

4.54e-084433PF09430
DomainDUF2012

NOMO2 NOMO3 NOMO1

4.54e-084433IPR019008
DomainCarb-bd-like_fold

NOMO2 NOMO3 NOMO1

6.31e-078433IPR013784
DomainRan_BP1

RGPD4 RGPD2 RANBP2

2.46e-0612433PF00638
DomainRANBD1

RGPD4 RGPD2 RANBP2

2.46e-0612433PS50196
DomainCarboxyPept_regulatory_dom

NOMO2 NOMO3 NOMO1

3.20e-0613433IPR014766
Domain-

NOMO2 NOMO3 NOMO1

3.20e-06134332.60.40.1120
DomainRanBD

RGPD4 RGPD2 RANBP2

3.20e-0613433SM00160
DomainRan_bind_dom

RGPD4 RGPD2 RANBP2

3.20e-0613433IPR000156
DomainCarboxyPept-like_regulatory

NOMO2 NOMO3 NOMO1

7.56e-0617433IPR008969
DomainGCC2_Rab_bind

RGPD4 RGPD2

1.08e-047432IPR032023
DomainRab_bind

RGPD4 RGPD2

1.08e-047432PF16704
Domain-

RGPD4 RGPD2

2.30e-04104321.10.220.60
DomainGrip

RGPD4 RGPD2

2.81e-0411432SM00755
DomainGRIP

RGPD4 RGPD2

2.81e-0411432PF01465
DomainGRIP_dom

RGPD4 RGPD2

3.37e-0412432IPR000237
DomainGRIP

RGPD4 RGPD2

3.37e-0412432PS50913
DomainTPR-contain_dom

RGPD4 RGPD2 RANBP2 VPS13A

3.87e-04150434IPR013026
DomainTPR_REGION

RGPD4 RGPD2 RANBP2 VPS13A

5.54e-04165434PS50293
DomainTPR

RGPD4 RGPD2 RANBP2 VPS13A

5.54e-04165434PS50005
DomainTPR

RGPD4 RGPD2 RANBP2

3.25e-03129433SM00028
DomainTPR_repeat

RGPD4 RGPD2 RANBP2

3.54e-03133433IPR019734
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 RGPD2 RANBP2

9.31e-0618333MM1549
PathwayREACTOME_EGR2_AND_SOX10_MEDIATED_INITIATION_OF_SCHWANN_CELL_MYELINATION

ADGRV1 TEAD1 PRX

4.10e-0529333M29808
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RGPD4 RGPD2 RANBP2

1.09e-0440333MM14945
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RGPD4 RGPD2 RANBP2

1.17e-0441333MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RGPD4 RGPD2 RANBP2

1.26e-0442333MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RGPD4 RGPD2 RANBP2

1.35e-0443333MM14609
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RGPD4 RGPD2 RANBP2

1.77e-0447333MM14939
PathwayREACTOME_GENE_SILENCING_BY_RNA

RGPD4 RGPD2 RANBP2

2.00e-0449333MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RGPD4 RGPD2 RANBP2

2.13e-0450333MM14610
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

RGPD4 RGPD2 RANBP2

2.25e-0451333MM15151
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

RGPD4 RGPD2 RANBP2

2.82e-0455333MM14917
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RGPD4 RGPD2 RANBP2

3.30e-0458333MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

RGPD4 RGPD2 RANBP2

3.30e-0458333MM14736
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

RGPD4 RGPD2 RANBP2

4.62e-0465333MM15147
PathwayREACTOME_SUMOYLATION

RGPD4 RGPD2 RANBP2 HIC1

6.22e-04169334MM14919
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CALCINEURIN_SIGNALING_PATHWAY

NFATC1 EGFR

6.25e-0416332M47449
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

RGPD4 RGPD2 RANBP2

6.50e-0473333MM14948
PathwayREACTOME_GLUCOSE_METABOLISM

RGPD4 RGPD2 RANBP2

9.13e-0482333MM15394
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

RGPD4 RGPD2 RANBP2

9.79e-0484333MM14929
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

RGPD4 RGPD2 RANBP2

1.05e-0386333MM15413
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

RGPD4 RGPD2 RANBP2

1.27e-0392333MM14951
Pubmed

Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.

NOMO2 NOMO3 NOMO1

1.76e-09343336011023
Pubmed

Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.

NOMO2 NOMO3 NOMO1

1.76e-09343325576386
Pubmed

1‑Palmitoyl‑2‑linoleoyl‑3‑acetyl‑rac‑glycerol ameliorates EGF‑induced MMP‑9 expression by promoting receptor desensitization in MDA‑MB‑231 cells.

TXNIP EPS15 EGFR

7.04e-09443332377695
Pubmed

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.

NOMO2 NOMO3 NOMO1

7.04e-09443331833031
Pubmed

A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.

NOMO2 NOMO3 NOMO1

7.04e-0944339267806
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RGPD2 RANBP2

6.14e-0874339037092
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RGPD2 RANBP2

6.14e-08743311353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD4 RGPD2 RANBP2

6.14e-08743330944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD4 RGPD2 RANBP2

6.14e-08743338838144
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD4 RGPD2 RANBP2

6.14e-0874337559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD4 RGPD2 RANBP2

6.14e-08743317372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD4 RGPD2 RANBP2

6.14e-08743338657106
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RGPD2 RANBP2

6.14e-08743321205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RGPD2 RANBP2

6.14e-08743318949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RGPD2 RANBP2

6.14e-08743325187515
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RGPD2 RANBP2

6.14e-0874338603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RGPD2 RANBP2

6.14e-08743326632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RGPD2 RANBP2

6.14e-08743324403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RGPD2 RANBP2

6.14e-08743323818861
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD4 RGPD2 RANBP2

6.14e-08743323536549
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD4 RGPD2 RANBP2

6.14e-08743312191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD4 RGPD2 RANBP2

6.14e-08743322821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD4 RGPD2 RANBP2

6.14e-08743320682751
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD4 RGPD2 RANBP2

9.82e-08843321670213
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD4 RGPD2 RANBP2

9.82e-08843327412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD4 RGPD2 RANBP2

9.82e-08843321310149
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD4 RGPD2 RANBP2

9.82e-08843322262462
Pubmed

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

NOMO2 NOMO3 NOMO1

9.82e-08843315257293
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD4 RGPD2 RANBP2

9.82e-08843328745977
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RGPD2 RANBP2

1.47e-07943318394993
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD4 RGPD2 RANBP2

1.47e-07943328100513
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD4 RGPD2 RANBP2

1.47e-07943317887960
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD4 RGPD2 RANBP2

1.47e-07943311553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD4 RGPD2 RANBP2

1.47e-07943310601307
Pubmed

Substrate-driven assembly of a translocon for multipass membrane proteins.

NOMO2 NOMO3 NOMO1

1.47e-07943336261522
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD4 RGPD2 RANBP2

1.47e-0794339733766
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD4 RGPD2 RANBP2

1.47e-07943328877029
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD4 RGPD2 RANBP2

2.10e-071043327160050
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD4 RGPD2 RANBP2

2.10e-071043316332688
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD4 RGPD2 RANBP2

2.10e-07104338857542
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD4 RGPD2 RANBP2

2.10e-071043321859863
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RGPD4 RGPD2 RANBP2

2.88e-071143317069463
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RGPD4 RGPD2 RANBP2

2.88e-071143335771867
Pubmed

An ER translocon for multi-pass membrane protein biogenesis.

NOMO2 NOMO3 NOMO1

2.88e-071143332820719
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD4 RGPD2 RANBP2

2.88e-071143334110283
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RGPD4 RGPD2 RANBP2

4.99e-071343331427429
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

RANBP2 TRMT61B NFATC1 DSG2 NOMO2 NOMO3 NOMO1 VPS13A

6.88e-0760643836538041
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RGPD4 RGPD2 RANBP2

7.93e-071543314697343
Pubmed

C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism.

TXNIP NFATC1

1.49e-06243233323975
Pubmed

c-Src/Cav1-dependent activation of the EGFR by Dsg2.

EGFR DSG2

1.49e-06243226918609
Pubmed

Recycling of the epidermal growth factor receptor is mediated by a novel form of the clathrin adaptor protein Eps15.

EPS15 EGFR

1.49e-06243221832070
Pubmed

EGFR and ADAMs cooperate to regulate shedding and endocytic trafficking of the desmosomal cadherin desmoglein 2.

EGFR DSG2

1.49e-06243218987342
Pubmed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

RGPD4 RGPD2 RANBP2

2.67e-062243327717094
Pubmed

NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar-Ductal Transdifferentiation in the Pancreas.

NFATC1 EGFR

4.48e-06343225623042
Pubmed

A chimeric pre-ubiquitinated EGF receptor is constitutively endocytosed in a clathrin-dependent, but kinase-independent manner.

EPS15 EGFR

4.48e-06343221226813
Pubmed

Hypermethylated in cancer 1 (HIC1) suppresses bladder cancer progression by targeting yes-associated protein (YAP) pathway.

HIC1 TEAD1

4.48e-06343230417565
Pubmed

Silibinin induces metabolic crisis in triple-negative breast cancer cells by modulating EGFR-MYC-TXNIP axis: potential therapeutic implications.

TXNIP EGFR

4.48e-06343232356386
Pubmed

USP9X Controls EGFR Fate by Deubiquitinating the Endocytic Adaptor Eps15.

EPS15 EGFR

4.48e-06343226748853
Pubmed

c-Cbl directs EGF receptors into an endocytic pathway that involves the ubiquitin-interacting motif of Eps15.

EPS15 EGFR

4.48e-06343215383614
Pubmed

Fibrillin-1 directly regulates osteoclast formation and function by a dual mechanism.

FBN1 NFATC1

4.48e-06343224039232
Pubmed

TXNIP interaction with the Her-1/2 pathway contributes to overall survival in breast cancer.

TXNIP EGFR

4.48e-06343225605021
Pubmed

Lipopolysaccharide-primed heterotolerant dendritic cells suppress experimental autoimmune uveoretinitis by multiple mechanisms.

IRF3 NFATC1

4.48e-06343227859049
Pubmed

Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment.

EPS15 EGFR

4.48e-06343215465819
Pubmed

Clathrin-independent endocytosis of ubiquitinated cargos.

EPS15 EGFR

4.48e-06343215701692
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

SCFD2 RANBP2 TMEM214 EGFR DSG2 ANO8 VPS13A

5.78e-0656843737774976
Pubmed

Hepatic lipase maturation: a partial proteome of interacting factors.

NOMO2 NOMO3 NOMO1

7.72e-063143319136429
Pubmed

Tyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosis.

EPS15 EGFR

8.94e-06443210953014
Pubmed

Post-transcriptional up-regulation of ADAM17 upon epidermal growth factor receptor activation and in breast tumors.

EGFR DSG2

8.94e-06443217227756
Pubmed

Stac proteins associate with the critical domain for excitation-contraction coupling in the II-III loop of CaV1.1.

STAC2 STAC3

8.94e-06443229467163
Pubmed

Association and colocalization of Eps15 with adaptor protein-2 and clathrin.

EPS15 EGFR

8.94e-0644329049247
Pubmed

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.

NOMO2 NOMO3 NOMO1

9.36e-063343330783098
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RGPD4 TXNIP RGPD2 EPS15 RANBP2 CHD7

1.22e-0541843634709266
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

RGPD4 RGPD2 RANBP2

1.44e-053843312791264
Pubmed

Distinct recruitment of Eps15 via Its coiled-coil domain is required for efficient down-regulation of the met receptor tyrosine kinase.

EPS15 EGFR

1.49e-05543219109251
Pubmed

Loss of connexin45 causes a cushion defect in early cardiogenesis.

GJA5 NFATC1

1.49e-05543210903175
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

FSIP2 RANBP2 TMEM214 FBN1

1.65e-0512343426912792
Pubmed

Skeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractility.

STAC2 STAC3

2.23e-05643223818578
Pubmed

HIV: Slipping under the radar.

IRF3 RANBP2

2.23e-05643224196714
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD4 RGPD2

3.12e-05743215710750
Pubmed

Endothelial deletion of PTBP1 disrupts ventricular chamber development.

GJA5 NFATC1

3.12e-05743237002228
Pubmed

Deregulated FGF and homeotic gene expression underlies cerebellar vermis hypoplasia in CHARGE syndrome.

GBX2 CHD7

3.12e-05743224368733
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

RGPD4 RGPD2 RANBP2 CHD7

3.24e-0514643423892456
Pubmed

Single-cell analysis of early progenitor cells that build coronary arteries.

GJA5 NFATC1

4.16e-05843229973725
Pubmed

A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling.

EPS15 EGFR

4.16e-05843216862145
Pubmed

Transcription Factor CTIP2 Maintains Hair Follicle Stem Cell Pool and Contributes to Altered Expression of LHX2 and NFATC1.

NFATC1 EGFR

4.16e-05843226176759
Pubmed

NFATC1 promotes epicardium-derived cell invasion into myocardium.

GJA5 NFATC1

4.16e-05843221447555
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

IRF3 GBX2 HIC1 CUX2 TEAD1 NFATC1

5.31e-0554443628473536
Pubmed

SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking.

EPS15 EGFR

5.35e-05943223222715
Pubmed

Dysregulation of connexins and inactivation of NFATc1 in the cardiovascular system of Nkx2-5 null mutants.

GJA5 NFATC1

5.35e-05943215850572
Pubmed

HIV-1 evades innate immune recognition through specific cofactor recruitment.

IRF3 RANBP2

5.35e-05943224196705
Pubmed

MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment.

EGFR MAP3K2

5.35e-05943219289468
Pubmed

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.

EPS15 HIC1 CUX2 CHD7 EGFR

5.42e-0533143520634891
Pubmed

USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification.

TXNIP EPS15 EGFR

6.33e-056243331340145
Pubmed

Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking, and activity of the nonselective cation channel TRPC6.

NOMO2 NOMO3 NOMO1

6.64e-056343331266804
Pubmed

Regulation of ubiquitin-binding proteins by monoubiquitination.

EPS15 EGFR

6.68e-051043216429130
Pubmed

Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation.

EPS15 EGFR

8.15e-051143215962011
Pubmed

CHD7 interacts with BMP R-SMADs to epigenetically regulate cardiogenesis in mice.

CHD7 NFATC1

8.15e-051143224293546
Pubmed

The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression.

GBX2 CHD7

8.15e-051143228165338
Pubmed

Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls.

GJA5 NFATC1

8.15e-051143227056912
Pubmed

Pax9 is required for cardiovascular development and interacts with Tbx1 in the pharyngeal endoderm to control 4th pharyngeal arch artery morphogenesis.

GBX2 CHD7

8.15e-051143231444215
InteractionRGPD4 interactions

RGPD4 RGPD2 RANBP2

1.35e-0522433int:RGPD4
InteractionRGPD8 interactions

RGPD4 RGPD2 RANBP2 EGFR

1.85e-0574434int:RGPD8
InteractionRGPD2 interactions

RGPD4 RGPD2 RANBP2

2.55e-0527433int:RGPD2
InteractionNCLN interactions

TMEM214 EGFR NOMO2 NOMO3 NOMO1

4.25e-05183435int:NCLN
InteractionCLEC16A interactions

RANBP2 TRMT61B NFATC1 DSG2 NOMO2 NOMO3 NOMO1 VPS13A

4.75e-05629438int:CLEC16A
Cytoband2q12.3

RGPD4 RANBP2

1.21e-04174422q12.3
Cytoband1q21.1

TXNIP GJA5

1.64e-03624421q21.1
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 RGPD2 RANBP2

5.86e-04115263769
GeneFamilyPDZ domain containing

LRRC7 PRX

2.00e-021522621220
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_7DY_NEGATIVE

RGPD4 RGPD2 RANBP2 NOMO2 NOMO3 MAP3K2 NOMO1

1.30e-05474447M40991
CoexpressionRAF_UP.V1_UP

GJA5 TEAD1 KHDRBS3 EGFR ENPEP

1.77e-05193445M2728
CoexpressionHUANG_GATA2_TARGETS_DN

GBX2 NOMO2 NOMO3 NOMO1

2.22e-0598444MM942
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP

RGPD4 RGPD2 RANBP2

2.32e-0533443MM477
CoexpressionGAO_ESOPHAGUS_25W_C4_FGFR1HIGH_EPITHELIAL_CELLS

FSIP2 HIC1 FBN1 TNFAIP6 NOMO1

2.53e-05208445M39139
CoexpressionTABULA_MURIS_SENIS_TRACHEA_GRANULOCYTE_AGEING

RGPD4 RGPD2 RANBP2

5.20e-0543443MM3857
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

TXNIP STAC2 HHIP HIC1 ADGRV1 NFATC1 EGFR DSG2 MGAT5B

6.12e-051074449M1941
CoexpressionGSE9946_IMMATURE_VS_MATURE_STIMULATORY_DC_DN

LRRC7 TNFAIP6 KHDRBS3 EGFR

8.24e-05137444M417
CoexpressionBLANCO_MELO_BRONCHIAL_EPITHELIAL_CELLS_INFLUENZA_A_INFECTION_UP

RALGAPA2 EGFR NOMO2 NOMO3

8.24e-05137444M34024
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000

CNTN4 GJA5 LRRC7 FBN1 EGFR ENPEP

1.18e-05261426gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_200

HHIP FBN1 EGFR ENPEP

2.07e-0582424gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_100

HHIP FBN1 ENPEP

5.34e-0537423gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_100
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_1000

CNTN4 GJA5 LRRC7 CUX2 CHD7 FBN1 EGFR ENPEP

8.17e-05734428gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_1000
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_500

GJA5 LRRC7 CUX2 FBN1 EGFR ENPEP

8.42e-05371426gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_500
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_500

GJA5 LRRC7 EGFR ENPEP

1.15e-04127424gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k2_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500

HHIP FBN1 EGFR ENPEP

1.25e-04130424gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200

HHIP FBN1 EGFR ENPEP

1.96e-04146424gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200

HHIP FBN1 EGFR ENPEP

2.01e-04147424gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_200
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_200

HHIP FBN1 ENPEP

2.17e-0459423gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_200
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_k-means-cluster#1_top-relative-expression-ranked_500

CNTN4 HHIP TNFAIP6

2.39e-0461423gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_500_k1
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500

HHIP FBN1 EGFR ENPEP

2.52e-04156424gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_200

CUX2 CHD7 TNFAIP6

2.89e-0465423gudmap_kidney_P3_CapMes_Crym_k4_200
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500

HHIP FBN1 EGFR ENPEP

3.13e-04165424gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_200

CUX2 CHD7 TNFAIP6 ENPEP

3.20e-04166424gudmap_kidney_P3_CapMes_Crym_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_100

HHIP FBN1 ENPEP

4.06e-0473423gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_100
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

MOK RANBP2 CHD7 KHDRBS3 VPS13A

4.54e-04328425Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_100

HHIP FBN1 ENPEP

4.58e-0476423gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_100
CoexpressionAtlaskidney_e10.5_UretericTip_HoxB7_k-means-cluster#1_top-relative-expression-ranked_200

CUX2 CHD7

5.10e-0417422gudmap_kidney_e10.5_UretericTip_HoxB7_k1_200
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

HHIP FBN1 EGFR ENPEP

5.44e-04191424gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k4_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000

CNTN4 CUX2 CHD7 ADGRV1 KHDRBS3 EGFR DSG2 ENPEP

5.56e-04973428Facebase_RNAseq_e9.5_Olfactory Placode_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000

CNTN4 CUX2 FBN1 EGFR MGAT5B ENPEP STAC3 PYHIN1

5.56e-04973428Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000
ToppCellIPF-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

TXNIP GJA5 EGFR NOMO2 NOMO3 NOMO1

3.44e-08192446e911e286da26202853f9650ba3cdefe5a5c9b585
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

GJA5 EGFR NOMO2 NOMO3 NOMO1

1.24e-06191445ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SCFD2 FBN1 DENND5A NFATC1 EGFR

1.48e-06198445a860246bcea847249a78fd2e86ed8e04371060db
ToppCellstromal_cell|World / Lineage and Cell class

FBN1 TNFAIP6 TEAD1 EGFR ENPEP

1.52e-06199445507a82d0529b5b1fa5aebcfe43db53f0b6e3f8f0
ToppCellstromal_cell-stromal_cell|World / Lineage and Cell class

FBN1 TNFAIP6 TEAD1 EGFR ENPEP

1.52e-0619944574262363a34da3a1eb55ab375fd61ddd7bb39b23
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FSIP2 CNTN4 STAC2 MAP3K2

5.82e-061194448eefcf1ace62ad1c90fa5b62ec159c83ec527bf3
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HHIP CHD7 TNFAIP6 ADGRV1

1.45e-05150444b30f52b94ce772632a1f2f5e0837db876cf92651
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HHIP CHD7 TNFAIP6 ADGRV1

1.45e-0515044405b9a9cbc5a95cdaf45d5f173e132acd4da9aa8a
ToppCellfacs-Heart-LV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 FBN1 TNFAIP6 EGFR

2.32e-05169444849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SCFD2 FBN1 NFATC1 EGFR

2.66e-05175444910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SCFD2 FBN1 NFATC1 EGFR

2.66e-05175444f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHIP FBN1 TNFAIP6 TEAD1

2.84e-0517844427497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHIP FBN1 TNFAIP6 TEAD1

2.84e-05178444d348a9550db940d204706529759dc51e30506b5f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTN4 ADGRV1 TEAD1 EGFR

2.90e-05179444cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CNTN4 HHIP FBN1 TNFAIP6

3.03e-051814449b2d207dc9fc2228a1555ed360286bb7c2d988ff
ToppCellCOPD-Endothelial-VE_Arterial|World / Disease state, Lineage and Cell class

GJA5 TEAD1 RALGAPA2 EGFR

3.44e-05187444be42ee71d3412bb1f52593d8814de85c354a0efa
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CNTN4 FBN1 TEAD1 KHDRBS3

3.44e-05187444ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

GJA5 RALGAPA2 MGAT5B PRX

3.44e-05187444fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

RANBP2 FBN1 TNFAIP6 EGFR

3.59e-0518944446e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 DENND5A NFATC1 EGFR

3.67e-051904441121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 DENND5A NFATC1 EGFR

3.67e-05190444048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTN4 ADGRV1 TEAD1 EGFR

3.74e-05191444e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellControl-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

GJA5 NOMO2 NOMO3 NOMO1

3.82e-051924447e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

CNTN4 ADGRV1 TEAD1 EGFR

3.82e-05192444efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 TNFAIP6 EGFR ENPEP

3.90e-05193444316ebdf15f75d88c348f909b643fcd315364ca84
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 TNFAIP6 EGFR ENPEP

3.90e-051934441afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCellCOPD-Endothelial-VE_Arterial|COPD / Disease state, Lineage and Cell class

GJA5 TEAD1 RALGAPA2 EGFR

3.90e-051934441c701b6ab5f0f0239634adac94fa1c92bf3c36f4
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HHIP FBN1 TNFAIP6 EGFR

3.90e-05193444d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCellLA-14._Fibroblast_III|LA / Chamber and Cluster_Paper

DENND5A TNFAIP6 KHDRBS3 EGFR

3.90e-051934447426c291bac59e539c427bcaae18abc7d397d44e
ToppCelldroplet-Fat-Scat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 TNFAIP6 EGFR ENPEP

3.90e-051934448dc6db335678f3a5cfd36026ad811fed8d9cb4bc
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CNTN4 FBN1 KHDRBS3 EGFR

3.98e-051944445594f7437448cb4b37d2d100f44d30c4a367df26
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Mesenchymal|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

HIC1 FBN1 TNFAIP6 NFATC1

3.98e-05194444638b9fdce64ed00243b5303800ec66207d5fd640
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Mesenchymal-choroid_plexus/mesenchymal-like_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

HIC1 FBN1 TNFAIP6 NFATC1

3.98e-05194444e9868c22934b6c0ac35e3e8270ec0b671bc6582a
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HHIP ADGRV1 TEAD1 EGFR

3.98e-0519444453f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellCOPD-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

GJA5 RALGAPA2 EGFR PRX

3.98e-0519444468705a6eca947c5b42b943d5224a7aef2a744007
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

FBN1 TNFAIP6 KHDRBS3 EGFR

3.98e-05194444d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GJA5 HIC1 TEAD1 ENPEP

3.98e-0519444478dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCellLA-14._Fibroblast_III|World / Chamber and Cluster_Paper

FBN1 TNFAIP6 KHDRBS3 EGFR

3.98e-05194444803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCellCOPD-Endothelial-VE_Capillary_B|COPD / Disease state, Lineage and Cell class

GJA5 RALGAPA2 EGFR PRX

3.98e-0519444418b7f901c12ca4f21f9a1eafd092aefe4d668b6d
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-8|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

FBN1 TNFAIP6 ENPEP STAC3

3.98e-0519444455b97095a7a17a312c616703d291738a0f806339
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HHIP FBN1 TNFAIP6 NFATC1

4.06e-051954440feb6ebe7b4b781dec7cfaef844140cfbf84b4b9
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HHIP FBN1 TNFAIP6 NFATC1

4.06e-051954442a6f67875cef140b0e6b8401436719675c6b3665
ToppCellfacs-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HHIP FBN1 EGFR ENPEP

4.06e-05195444c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCellControl-Epithelial|Control / Disease state, Lineage and Cell class

HHIP ADGRV1 TEAD1 EGFR

4.06e-051954441798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCellIPF-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

TXNIP GJA5 EGFR PRX

4.14e-051964448f0f72ead06abe02b575e443552eacc2151077ef
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FBN1 TEAD1 EGFR ENPEP

4.22e-051974443bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FBN1 TEAD1 EGFR ENPEP

4.22e-0519744417344464fdcc5ba0c03959696b97c195f11e644c
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FBN1 TEAD1 EGFR ENPEP

4.22e-051974445b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCellFibroblasts-HLA-DRA_high_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FBN1 TNFAIP6 TEAD1 EGFR

4.30e-05198444e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCellFibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FBN1 TNFAIP6 TEAD1 EGFR

4.39e-0519944440de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuroepithelial|2m / Sample Type, Dataset, Time_group, and Cell type.

HHIP HIC1 FBN1 TNFAIP6

4.48e-052004443da9441c0f1e242f0d195de47ecd4c24dfdca232
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuroepithelial-Proteoglycan-expressing_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

HHIP HIC1 FBN1 TNFAIP6

4.48e-05200444eed2bafddcd041ef5fcc4d1d31edb8be4d83ce01
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

HHIP TNFAIP6 ADGRV1

2.38e-041224432880f25d10a7765e55a2aa20c7a6ef74cea19c4d
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

HHIP TNFAIP6 ADGRV1

2.38e-04122443ecd0e54dd829201290212ea2ff7c8e7eec19c0e9
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

HHIP TNFAIP6 ADGRV1

2.38e-04122443cffd7730bda90828efc0def452cabb44cf93ab48
ToppCellPosterior_cortex-Macroglia-OLIGODENDROCYTE|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

HHIP TNFAIP6 ADGRV1

2.49e-041244439f169fa17be1842a6bd83778ff30465a740edd5f
ToppCellThalamus-Macroglia-OLIGODENDROCYTE|Thalamus / BrainAtlas - Mouse McCarroll V32

DENND5A TNFAIP6 ADGRV1

2.80e-04129443b3cb0c10659d1216b8f7de3aa1f9aac101cb65dd
ToppCellTCGA-Bone_and_Soft_Tissue|World / Sample_Type by Project: Shred V9

HIC1 FBN1 IHO1

3.13e-041344439940a710a5d6670244cce5e19f88b4195a59875b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Serpinf1-Serpinf1_Aqp5_Vip|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTN4 EGFR MGAT5B

3.27e-041364438f5682422ba0b477c1e0700212948457f106cb10
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Serpinb1a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HHIP TNFAIP6 ADGRV1

3.34e-04137443ca8fdbe66a854e6283b22179ec9359ea9e86cd8e
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE|Hippocampus / BrainAtlas - Mouse McCarroll V32

HHIP TNFAIP6 ADGRV1

3.34e-041374435e97480f014f1d9267e8126f1d0e58acd22f36aa
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Serpinb1a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HHIP TNFAIP6 ADGRV1

3.48e-04139443789edd3c98e7c5c1cc402c780fded9a9dfd1dfb8
ToppCell10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-MPP_myeloid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

STAC2 ENPEP PRX

3.56e-04140443eb1d22f5f5dbf60b6485464baec4be9b3060f65c
ToppCelltumor_Lung-T/NK_cells-Naive_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

TXNIP PRX PYHIN1

3.63e-04141443f62d78b3f998f3ea493647c4c5b86cfec2243f0b
ToppCellMild/Remission-B_naive-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

RGPD4 TXNIP GPX1

3.78e-04143443bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RGPD2 PRX IHO1

3.86e-04144443f6061dd965a2b2fe6ad864f8aecc06d2e74881ce
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-7|TCGA-Endometrium / Sample_Type by Project: Shred V9

CNTN4 GJA5 ENPEP

3.94e-04145443ffbdadea0185e5d3b85f2868d5ec82b50cf2e2a1
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HHIP TNFAIP6 ADGRV1

4.18e-0414844344128692824ca419fface0af41099c17135933ce
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HHIP TNFAIP6 ADGRV1

4.18e-04148443d60f93311cfa718d026a0dbf61771bbbcbb79146
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Serpinf1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTN4 EGFR MGAT5B

4.27e-041494435293c50b3fb41b1edaf9a97354899bd13770078c
ToppCell368C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CNTN4 HHIP ANO8

4.27e-04149443f53151d9e5e724a61be0ee6a8c740d1990f28d5f
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

CNTN4 STAC2 LRRC7

4.27e-041494436e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCell368C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CNTN4 HHIP ANO8

4.27e-041494439286bc56ff2e245630537a0bda5f1a1e17be863a
ToppCellmetastatic_Brain-Fibroblasts-Smooth_muscle_cells|Fibroblasts / Location, Cell class and cell subclass

GBX2 STAC2 PRX

4.70e-04154443423f58fc7dcef068458cbf7b4ee989e37227041e
ToppCellfacs-Marrow-KLS-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 ADGRV1 PRX

4.70e-0415444337765512dfae557b9f6eb30a29463b93682a4404
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 ADGRV1 PRX

4.79e-04155443c58a5fb8d853f12204e961d633e83452eb12a659
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIC1 ADGRV1 PRX

4.79e-041554439cb8c42c2e451b2d4dcd7154a4b1bfd21bbb7ea8
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FSIP2 CNTN4 LRRC7

4.79e-0415544377fdae85d36efb776db977eb424b32487ef222e4
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MOK TNFAIP6 PRX

4.88e-041564430b3630fd4479291599e1674e87eba6f93877ac3a
ToppCell368C-Fibroblasts-Fibroblast-F|368C / Donor, Lineage, Cell class and subclass (all cells)

CNTN4 HHIP FBN1

4.97e-0415744374038192f016f95f80e0189035ee8ccc22ceb1b8
ToppCell368C-Fibroblasts-Fibroblast-F-|368C / Donor, Lineage, Cell class and subclass (all cells)

CNTN4 HHIP FBN1

4.97e-04157443982e6ea78c7dabdb7c07c4a5fb2425d5e45b5b94
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

CNTN4 KHDRBS3 VPS13A

5.16e-0415944318e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTN4 ADGRV1 EGFR

5.16e-041594438680b054622f573a82b1625fb93c2d5db81d1034
ToppCelldroplet-Fat-SCAT-30m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 GJA5 PRX

5.25e-0416044367ee7a314d7d4d3ea206e0158083f36f6dd7e80b
ToppCelldroplet-Fat-SCAT-30m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 GJA5 PRX

5.25e-04160443759749f708c3a2b36692d42499f19aff937e592f
ToppCelldroplet-Fat-SCAT-30m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 GJA5 PRX

5.25e-04160443fc76337ad766c859db390ef8b6fb9caeaace3a56
ToppCellIPF-Epithelial-Ionocyte|World / Disease state, Lineage and Cell class

STAC2 EGFR DSG2

5.35e-04161443f1cd5c938cdc08ad8995371b72493850a6cf277a
ToppCellsevere-HSPC|severe / disease stage, cell group and cell class

FBN1 KHDRBS3 DSG2

5.74e-04165443acd837d88ad3786c263f74651a6c0e02fa2fa2c5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CUX2 PYHIN1 VPS13A

5.95e-0416744383969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCellCOVID-19-kidney-Lymphatic_EC|kidney / Disease (COVID-19 only), tissue and cell type

FBN1 RALGAPA2 NFATC1

5.95e-0416744397d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

HIC1 FBN1 TNFAIP6

6.05e-04168443aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellControl|World / group, cell type (main and fine annotations)

CNTN4 ADGRV1 EGFR

6.05e-04168443a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC7 FBN1 TNFAIP6

6.05e-041684434b2d29a7843bf45922038c093ca7ec0600756adc
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HHIP CUX2 ENPEP

6.16e-0416944316c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCellsevere_influenza-gd_T|World / disease group, cell group and cell class (v2)

TXNIP HHIP PYHIN1

6.16e-041694436d514dd2d1e5253bce49279f43aa2fa2b7c2653e
ToppCellsevere-HSPC|World / disease stage, cell group and cell class

FBN1 KHDRBS3 DSG2

6.16e-04169443b0421b73bfdc92f7a2762b4b670b9eae124aa702
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

FSIP2 PYHIN1 VPS13A

6.16e-04169443bea8aba1f3cc3d0e8d448c1c45f5354d26ebf850
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADGRV1 ENPEP STAC3

6.26e-04170443ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

ADGRV1 TEAD1 EGFR

6.26e-04170443e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC7 FBN1 TNFAIP6

6.37e-041714435d31fc9b60329d4ae3c77e4ca679359d9314397d
Diseasebrain disease (is_implicated_in)

IRF3 RANBP2

1.36e-0412432DOID:936 (is_implicated_in)
Diseasemaximum cigarettes per day measurement

NFATC1 EGFR

3.13e-0418432EFO_0009264
Diseasehypertension (biomarker_via_orthology)

GJA5 FBN1 EGFR GPX1

3.33e-04227434DOID:10763 (biomarker_via_orthology)
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

EGFR GPX1

3.49e-0419432DOID:2876 (is_marker_for)
Diseaseglomerulonephritis (biomarker_via_orthology)

GJA5 FBN1

3.88e-0420432DOID:2921 (biomarker_via_orthology)
DiseaseHead Neoplasms

EGFR GPX1

5.61e-0424432C0018675
DiseaseUpper Aerodigestive Tract Neoplasms

EGFR GPX1

5.61e-0424432C0887900
DiseaseCancer of Head

EGFR GPX1

5.61e-0424432C0751177
DiseaseNeck Neoplasms

EGFR GPX1

6.09e-0425432C0027533
DiseaseCancer of Neck

EGFR GPX1

6.09e-0425432C0746787
DiseaseEndogenous Hyperinsulinism

FBN1 GPX1

6.59e-0426432C1257963
DiseaseExogenous Hyperinsulinism

FBN1 GPX1

6.59e-0426432C1257964
DiseaseCompensatory Hyperinsulinemia

FBN1 GPX1

6.59e-0426432C1257965
Diseasehypertension, COVID-19

CUX2 ENPEP

7.11e-0427432EFO_0000537, MONDO_0100096
DiseaseHyperinsulinism

FBN1 GPX1

7.65e-0428432C0020459
Diseasethoracic aortic aneurysm

CNTN4 FBN1

8.79e-0430432EFO_0004282
DiseaseHyperglycemia, Postprandial

FBN1 GPX1

8.79e-0430432C1855520
DiseaseHyperglycemia

FBN1 GPX1

8.79e-0430432C0020456
Diseasehypertension

HIC1 LRRC7 CUX2 ENPEP

1.03e-03307434EFO_0000537
DiseaseHead and Neck Neoplasms

EGFR GPX1

1.06e-0333432C0018671

Protein segments in the cluster

PeptideGeneStartEntry
PGGGFEPNFMLFEKC

GPX1

101

P07203
FPKRFQIVLFDPKGG

ADGRV1

5591

Q8WXG9
KVGVFNNKGEGPFSP

CNTN4

776

Q8IWV2
AFKGEAGGLLVFPPA

CUX2

496

O14529
PSKGFGKDDFPGGVD

CHD7

611

Q9P2D1
PKAFHAGKLFPFGGT

ANO8

1046

Q9HCE9
FGKKDPNFKGFSGAG

RANBP2

1961

P49792
QPGGKFAFFKVLPGD

NOMO3

166

P69849
GKGITEPPFGIFVFN

DSG2

91

Q14126
QPGGKFAFFKVLPGD

NOMO2

166

Q5JPE7
SGQGNPFKPSDKGIF

LRRC7

1466

Q96NW7
GPDGKGKLDFPEGVF

HIC1

636

Q14526
QLFGGDIKDGGLFPP

IHO1

91

Q8IYA8
VFRPDKGNQFPGGKV

FSIP2

5846

Q5CZC0
KAKLFIGFGFPYEGP

MGAT5B

526

Q3V5L5
DNPIFEKFGKGGTYP

MAP3K2

251

Q9Y2U5
KFPLGPAAAVFGRGE

NFATC1

11

O95644
QPGGKFAFFKVLPGD

NOMO1

166

Q15155
NFDFPFKKGSGIPLL

MOK

236

Q9UQ07
FFAKYPQAGAGEKPR

ENPEP

911

Q07075
KKPEVPFFGPLFDGA

RALGAPA2

1786

Q2PPJ7
PFFGPLFDGAIVSGK

RALGAPA2

1791

Q2PPJ7
FFPKEAKPNGIFKGS

EGFR

1176

P00533
KFAPQPLPGGGNFDK

GBX2

126

P52951
GPGFATKEITNGKPF

FBN1

1011

P35555
LENGPGGKFFNPFSN

GJA5

271

P36382
FPGDAGLGKLIEFFK

PYHIN1

56

Q6K0P9
GQGKYEPGFFPKLQS

DENND5A

661

Q6IQ26
QFPKFNFVGKLLGPR

KHDRBS3

66

O75525
FGKIDPFGGDPFKGS

EPS15

636

P42566
VPKDKEGGVFDLGPF

IRF3

311

Q14653
FGKKDPNFKGFSGAG

RGPD4

986

Q7Z3J3
FQFGKKDPNFKGFSG

RGPD2

976

P0DJD1
PDAIGGGAKQPKAVF

SCFD2

61

Q8WU76
LEFKPFSNGPLVGGF

HHIP

481

Q96QV1
PVGGICGQKQKPSFF

LINC00615

31

Q96LM1
GGVFTDPKQIFKSPG

TNFAIP6

136

P98066
KPIKGAQKGGAAGFF

VPS13A

2981

Q96RL7
AVPFGKIVGKFPGQI

TRMT61B

186

Q9BVS5
KGKIGDRVGFFPANF

STAC2

331

Q6ZMT1
FKGPRFALPKFGVRG

PRX

1016

Q9BXM0
GFGMIGPKDFFPLLD

TMEM214

311

Q6NUQ4
GGLKELFGKGPQNAF

TEAD1

271

P28347
FGFELPQGPLGTSFK

TXNIP

101

Q9H3M7
RGKIGEKVGFFPPNF

STAC3

286

Q96MF2