Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

CCP110 SPAG1 KAT5 CNTRL CEP290 GAS8 CUL9 SPAG5 FSIP2 DST SYNE2 PDE4DIP FER TAOK1 DIAPH3 CROCC GEN1

2.59e-0572015317GO:0000226
GeneOntologyBiologicalProcessregulation of attachment of spindle microtubules to kinetochore

ZWILCH KAT5 SPAG5 SIRT2

2.76e-05241534GO:0051988
GeneOntologyBiologicalProcessmicrotubule-based process

CCP110 SPAG1 KAT5 DNAH10 CNTRL CEP290 GAS8 CUL9 SPAG5 WDR19 FSIP2 DST SYNE2 PDE4DIP FER MACF1 TAOK1 DIAPH3 CROCC GEN1 IQUB

3.70e-05105815321GO:0007017
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

TDRD5 KAT5 SMCHD1 CNTRL VPS54 MDK DCST1 FSIP2 SIRT2 SPATA16 FER CCDC136 KNL1 TDRD12

3.96e-0552715314GO:0022412
GeneOntologyBiologicalProcessattachment of spindle microtubules to kinetochore

ZWILCH KAT5 SPAG5 SIRT2 KNL1

5.92e-05561535GO:0008608
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

KRT9 KRT78 VPS54 DST MACF1 BFSP2

9.59e-05991536GO:0045104
GeneOntologyBiologicalProcessintermediate filament-based process

KRT9 KRT78 VPS54 DST MACF1 BFSP2

1.01e-041001536GO:0045103
DomainLRRC37AB_C

LRRC37A3 LRRC37A2 LRRC37A

2.10e-0641523IPR029423
DomainLRRC37AB_C

LRRC37A3 LRRC37A2 LRRC37A

2.10e-0641523PF14914
DomainLRRC37_N

LRRC37A3 LRRC37A2 LRRC37A

2.10e-0641523IPR032754
DomainLRRC37

LRRC37A3 LRRC37A2 LRRC37A

2.10e-0641523PF15779
DomainLRRC37A/B-like

LRRC37A3 LRRC37A2 LRRC37A

2.10e-0641523IPR015753
DomainTPR-like_helical_dom

VPS11 SPAG1 TTC28 COPS3 TEX11 WDR19 TRANK1 SH3TC1 SPATA16 UTY NAA16

3.33e-0623315211IPR011990
Domain-

VPS11 SPAG1 TTC28 TEX11 WDR19 TRANK1 SH3TC1 SPATA16 UTY NAA16

7.69e-06207152101.25.40.10
DomainTPR_REGION

SPAG1 TTC28 DNAH10 WDR19 TRANK1 SH3TC1 UTY NAA16

6.25e-051651528PS50293
DomainTPR

SPAG1 TTC28 DNAH10 WDR19 TRANK1 SH3TC1 UTY NAA16

6.25e-051651528PS50005
DomainTPR

SPAG1 TTC28 TEX11 TRANK1 SH3TC1 UTY NAA16

8.98e-051291527SM00028
DomainTPR_repeat

SPAG1 TTC28 TEX11 TRANK1 SH3TC1 UTY NAA16

1.09e-041331527IPR019734
DomainSPEC

SESTD1 DST SYNE2 MACF1

1.27e-04321524SM00150
DomainSpectrin/alpha-actinin

SESTD1 DST SYNE2 MACF1

1.27e-04321524IPR018159
DomainTPR-contain_dom

SPAG1 TTC28 WDR19 TRANK1 SH3TC1 UTY NAA16

2.29e-041501527IPR013026
DomainSpectrin

DST SYNE2 MACF1

8.30e-04231523PF00435
DomainACTININ_2

DST SYNE2 MACF1

8.30e-04231523PS00020
DomainACTININ_1

DST SYNE2 MACF1

8.30e-04231523PS00019
DomainActinin_actin-bd_CS

DST SYNE2 MACF1

8.30e-04231523IPR001589
DomainTPR_1

SPAG1 TTC28 SH3TC1 UTY NAA16

8.43e-04901525IPR001440
DomainTPR_1

SPAG1 TTC28 SH3TC1 UTY NAA16

8.43e-04901525PF00515
Domain-

DST MACF1

9.66e-04615223.90.1290.10
DomainSMC_hinge

SMCHD1 SMC1B

9.66e-0461522SM00968
DomainGAR

DST MACF1

9.66e-0461522PS51460
DomainGAS2

DST MACF1

9.66e-0461522PF02187
DomainHaem_d1

WDR19 KMT2A

9.66e-0461522IPR011048
DomainSMC_hinge

SMCHD1 SMC1B

9.66e-0461522PF06470
Domain-

DST MACF1

9.66e-04615223.30.920.20
DomainSMC_hinge

SMCHD1 SMC1B

9.66e-0461522IPR010935
DomainGAS_dom

DST MACF1

9.66e-0461522IPR003108
DomainGAS2

DST MACF1

9.66e-0461522SM00243
Domain-

NLRP7 LRRC37A3 CNTRL LRRC37A2 LRRC74A LRRC19 LRRC37A NXF5 NLRP4

1.28e-0332115293.80.10.10
DomainClathrin

VPS11 WDR19

1.35e-0371522PF00637
DomainPlectin

DST MACF1

1.35e-0371522PF00681
DomainCullin_CS

CUL4B CUL9

1.35e-0371522IPR016157
DomainPlectin_repeat

DST MACF1

1.35e-0371522IPR001101
DomainPLEC

DST MACF1

1.35e-0371522SM00250
DomainL_dom-like

NLRP7 LRRC37A3 CNTRL LRRC37A2 LRRC74A LRRC19 LRRC37A NXF5 NLRP4

1.49e-033281529IPR032675
DomainSpectrin_repeat

DST SYNE2 MACF1

1.65e-03291523IPR002017
DomainLeu-rich_rpt

LRRC37A3 CNTRL LRRC37A2 LRRC74A LRRC19 LRRC37A NXF5 NLRP4

1.72e-032711528IPR001611
DomainClathrin_H-chain/VPS_repeat

VPS11 WDR19

1.78e-0381522IPR000547
DomainCullin_neddylation_domain

CUL4B CUL9

1.78e-0381522IPR019559
DomainCullin_Nedd8

CUL4B CUL9

1.78e-0381522PF10557
DomainCullin_Nedd8

CUL4B CUL9

1.78e-0381522SM00884
DomainZnf_RING_CS

PCGF1 CBLL2 CUL9 RNFT2 TRIM9 ARIH2

2.19e-031631526IPR017907
DomainCullin_homology

CUL4B CUL9

2.28e-0391522IPR016158
DomainHGTP_anticodon

EPRS1 TARS1

2.28e-0391522PF03129
DomainZF_RING_1

VPS11 PCGF1 CBLL2 CUL9 DCST1 RNFT2 TRIM9 ARIH2

2.68e-032911528PS00518
DomainCullin

CUL4B CUL9

2.84e-03101522PF00888
DomainCULLIN_2

CUL4B CUL9

2.84e-03101522PS50069
DomainCullin_N

CUL4B CUL9

2.84e-03101522IPR001373
DomainCULLIN_1

CUL4B CUL9

2.84e-03101522PS01256
DomainZF_RING_2

VPS11 PCGF1 CBLL2 CUL9 DCST1 RNFT2 TRIM9 ARIH2

3.09e-032981528PS50089
Domainaa-tRNA-synt_IIb

EPRS1 TARS1

3.45e-03111522IPR002314
Domain-

EPRS1 TARS1

3.45e-031115223.40.50.800
Domain-

SIRT2 NNT

3.45e-031115223.40.50.1220
DomaintRNA-synt_2b

EPRS1 TARS1

3.45e-03111522PF00587
DomainRING

VPS11 PCGF1 CBLL2 CUL9 DCST1 RNFT2 TRIM9 ARIH2

3.56e-033051528SM00184
DomainDHS-like_NAD/FAD-binding_dom

SIRT2 NNT

4.12e-03121522IPR029035
DomainZnf_RING

VPS11 PCGF1 CBLL2 CUL9 DCST1 RNFT2 TRIM9 ARIH2

5.29e-033261528IPR001841
DomainAnticodon-bd

EPRS1 TARS1

5.62e-03141522IPR004154
DomainIBR

CUL9 ARIH2

5.62e-03141522PF01485
DomainIBR

CUL9 ARIH2

5.62e-03141522SM00647
DomainTUDOR

TDRD5 TDRD12

5.62e-03141522PF00567
DomainIBR_dom

CUL9 ARIH2

6.44e-03151522IPR002867
Domain-

MYD88 NLRP7 CFLAR NLRP4

7.03e-039315241.10.533.10
DomainAcyltransferase

AGPAT4 GPAM

7.33e-03161522PF01553
DomainTPR_2

TTC28 SH3TC1 NAA16

7.83e-03501523PF07719
DomainTPR_2

TTC28 SH3TC1 NAA16

7.83e-03501523IPR013105
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

EPRS1 SEMA4D SESTD1 TTC28 RSL1D1 CEP290 TRIOBP CUL9 MYNN VPS54 STAT1 TXNDC11 WDR19 FRY DST TRIM9 ARIH2 PDE4DIP EIF4G1 MACF1 TAOK1 YY1AP1 GEN1 TARS1

6.54e-0912851612435914814
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MIX23 RPGRIP1 EPRS1 RPL28 SPAG1 NLRP7 RSL1D1 SMCHD1 CNTRL MYNN HEATR1 CFAP210 ACSM3 DST SNX25 LMLN SYNE2 SAP30BP EIF4G1 PLXNA4 KMT2A SNU13 MACF1 DIAPH3

5.77e-0814421612435575683
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CUL4B TTC28 TRIOBP DST TRIM9 SRGAP3 SYNE2 MACF1 PRDM16 UNC80

1.09e-072251611012168954
Pubmed

Human transcription factor protein interaction networks.

SIN3B RPL28 PCGF1 KAT5 DNAH10 RSL1D1 SMCHD1 NUP88 IKBKG CUL9 RREB1 LHX6 STAT1 DST TRIM9 SUDS3 SYNE2 EIF4G1 KMT2A ZFHX3 YY1AP1 TAF5L PRDM16

2.03e-0714291612335140242
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

EPRS1 SIN3B RPL28 RSL1D1 SMCHD1 NUP88 HEATR1 NPLOC4 STAT1 SPAG5 SIRT2 DST TRIM9 SAP30BP KMT2A MACF1 SCIN KNL1

3.77e-079341611833916271
Pubmed

Midkine induces tumor cell proliferation and binds to a high affinity signaling receptor associated with JAK tyrosine kinases.

MDK STAT1 JAK2

3.88e-07416139452495
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A3 LRRC37A2 LRRC37A

3.88e-074161322419166
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

CNKSR2 DST TRIM9 SRGAP3 ARIH2 PDE4DIP MACF1 CCDC136

5.61e-07151161817043677
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CCP110 SIN3B ARHGAP23 CEP290 ANKRD62 GPAM FIG4 MACF1 TAOK1 SCIN PRDM16 UNC80

3.56e-064931611215368895
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CCP110 RPL28 KRT9 TTC28 ELP1 CUL9 ZNF546 SIRT2 MACF1 YY1AP1 DIAPH3 SCIN KNL1

3.94e-065881611338580884
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

FNDC3B SPAG1 CYP24A1 CNTRL CEP290 GAS8 ITFG1 JAK2 RABGAP1L LMLN SCIN GEN1 IQUB MCOLN2

4.16e-066861611429987050
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

SIN3B TTC28 NUP88 IKBKG RB1CC1 RREB1 SPAG5 DST ZFHX3 DIAPH3 KNL1

4.40e-064181611134709266
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

EPRS1 RPL28 KRT78 RSL1D1 SMCHD1 CEP290 ELP1 HEATR1 RB1CC1 STAT1 DST SYNE2 EIF4G1 MACF1 SCIN NNT TARS1

5.97e-0610241611724711643
Pubmed

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.

CUL4B RSL1D1 NUP88 ELP1 COPS3 NPLOC4 SAP30BP MAPK3

7.06e-06212161833462405
Pubmed

Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome.

SESTD1 IKBKG PDE4DIP MACF1

7.14e-0627161418685082
Pubmed

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling.

MYD88 STAT1 MAPK3

8.01e-069161312872135
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

EPRS1 RPL28 KRT78 ARHGAP23 ELP1 CNKSR2 COPS3 SIRT2 DST TRIM9 SRGAP3 PDE4DIP EIF4G1 PLXNA4 MIOS KMT2A MACF1 MAPK3 CROCC TARS1

1.11e-0514311612037142655
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A3 LRRC37A2 LRRC37A

1.14e-0510161323064749
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CUL4B RSL1D1 SMCHD1 NUP88 ELP1 CUL9 HEATR1 DST SYNE2 EIF4G1 KMT2A MACF1 NNT

1.21e-056531611322586326
Pubmed

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.

RPGRIP1 CEP290 ELP1 RB1CC1 SYNE2 MACF1 CROCC LARGE1

1.40e-05233161832290105
Pubmed

JAK2, but not Src family kinases, is required for STAT, ERK, and Akt signaling in response to growth hormone in preadipocytes and hepatoma cells.

STAT1 JAK2 MAPK3

1.56e-0511161318499741
Pubmed

MyD88-dependent signaling in non-parenchymal cells promotes liver carcinogenesis.

MYD88 IKBKG

2.13e-052161230770929
Pubmed

Lack of Association between Genetic Polymorphisms of JAK-STAT Signaling Pathway Genes and Acute Anterior Uveitis in Han Chinese.

STAT1 JAK2

2.13e-052161227965977
Pubmed

STAT1 activation in association with JAK2 exon 12 mutations.

STAT1 JAK2

2.13e-052161226635038
Pubmed

Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.

DST MACF1

2.13e-052161211002341
Pubmed

Imbalance between HDAC and HAT activities drives aberrant STAT1/MyD88 expression in macrophages from type 1 diabetic mice.

MYD88 STAT1

2.13e-052161227623388
Pubmed

Furry promotes acetylation of microtubules in the mitotic spindle by inhibition of SIRT2 tubulin deacetylase.

FRY SIRT2

2.13e-052161223886946
Pubmed

The peptide encoded by a novel putative lncRNA HBVPTPAP inducing the apoptosis of hepatocellular carcinoma cells by modulating JAK/STAT signaling pathways.

STAT1 JAK2

2.13e-052161232755630
Pubmed

Characterization of the MLL partner gene AF15q14 involved in t(11;15)(q23;q14).

KMT2A KNL1

2.13e-052161212618768
Pubmed

Neurotensin enhances nitric oxide generation via the JAK2-STAT1 pathway in murine macrophage Raw264.7 cells during costimulation with LPS and IFNgamma.

STAT1 JAK2

2.13e-052161216563502
Pubmed

Haplotypes of the Mutated SIRT2 Promoter Contributing to Transcription Factor Binding and Type 2 Diabetes Susceptibility.

STAT1 SIRT2

2.13e-052161232438712
Pubmed

Activation of JAK2/STAT1-alpha-dependent signaling events during Mycobacterium tuberculosis-induced macrophage apoptosis.

STAT1 JAK2

2.13e-052161212426001
Pubmed

HBx-induced NF-κB signaling in liver cells is potentially mediated by the ternary complex of HBx with p22-FLIP and NEMO.

IKBKG CFLAR

2.13e-052161223483900
Pubmed

CSN3 interacts with IKKgamma and inhibits TNF- but not IL-1-induced NF-kappaB activation.

IKBKG COPS3

2.13e-052161211418127
Pubmed

Endothelial transcriptomic changes induced by oxidized low density lipoprotein disclose an up-regulation of Jak-Stat pathway.

STAT1 JAK2

2.13e-052161226028607
Pubmed

Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways.

MYD88 STAT1

2.13e-052161221125645
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TTC28 CUL9 CNKSR2 SRGAP3 RABGAP1L PDE4DIP MACF1 YY1AP1 CROCC LARGE1

2.18e-054071611012693553
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

RSL1D1 SMCHD1 SHMT1 HAT1 HEATR1 STAT1 DST SRGAP3 SYNE2 SNU13 MACF1

2.25e-054981611136634849
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

NUP88 FSIP2 DST LMLN SYNE2 EIF4G1

2.44e-05123161626912792
Pubmed

Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock.

RB1CC1 STAT1 JAK2

3.41e-0514161331346084
Pubmed

Interaction network of human early embryonic transcription factors.

PCGF1 KAT5 NUP88 RREB1 SUDS3 KMT2A ZFHX3 TAF5L PRDM16

4.08e-05351161938297188
Pubmed

Identification of host proteins required for HIV infection through a functional genomic screen.

SESTD1 RSL1D1 IKBKG FAM76B HEATR1 FAM228B TAOK1 IQUB

4.23e-05272161818187620
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

EPRS1 SESTD1 ZWILCH NET1 RSL1D1 CNTRL SHMT1 FAM76B HEATR1 STAT1 SPAG5 MACF1 TAOK1 CCDC171 GEN1 NLRP4

4.69e-0510841611611544199
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

CUL4B EPRS1 RPL28 NUP88 IKBKG SHMT1 ELP1 HAT1 COPS3 ERI1 RRM1 NPLOC4 STAT1 ARIH2 EIF4G1 SNU13 MACF1 CROCC TARS1

4.71e-0514551611922863883
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

CUL4B KRT9 NUP88 RRM1 NPLOC4 STAT1 GFM2 MIOS NNT TARS1

5.18e-054511611036168627
Pubmed

EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice.

MYD88 STAT1 JAK2 MAPK3

5.20e-0544161435493520
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

SESTD1 NET1 SMCHD1 IKBKG RB1CC1 DST PDE4DIP TAOK1 LARGE1

5.28e-05363161914691545
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

EPRS1 FNDC3B TTC28 ARHGAP23 ELP1 LANCL1 GPAM NPLOC4 SPAG5 DST KMT2A YY1AP1

5.45e-056501611238777146
Pubmed

JAK2/STAT1-mediated HMGB1 translocation increases inflammation and cell death in a ventilator-induced lung injury model.

STAT1 JAK2

6.37e-053161231467427
Pubmed

Progesterone activates Janus Kinase 1/2 and activators of transcription 1 (JAK1-2/STAT1) pathway in human spermatozoa.

STAT1 JAK2

6.37e-053161222748021
Pubmed

Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing.

SYNE2 MAPK3

6.37e-053161225744025
Pubmed

Foot-and-mouth disease virus structural protein VP3 degrades Janus kinase 1 to inhibit IFN-γ signal transduction pathways.

STAT1 JAK2

6.37e-053161226901336
Pubmed

Expression of the mouse Macf2 gene during inner ear development.

DST MACF1

6.37e-053161212399109
Pubmed

Effects of MAPK signaling on 1,25-dihydroxyvitamin D-mediated CYP24 gene expression in the enterocyte-like cell line, Caco-2.

CYP24A1 MAPK3

6.37e-053161219097033
Pubmed

Chromosomal localization of genes encoding CAN/Nup214-interacting proteins--human CRM1 localizes to 2p16, whereas Nup88 localizes to 17p13 and is physically linked to SF2p32.

NUP88 STAT1

6.37e-05316129205132
Pubmed

Candidate genes for COPD in two large data sets.

STAT1 SIRT2

6.37e-053161220562129
Pubmed

Loss of Stat1 decreases megakaryopoiesis and favors erythropoiesis in a JAK2-V617F-driven mouse model of MPNs.

STAT1 JAK2

6.37e-053161224820309
Pubmed

A t(11;15) fuses MLL to two different genes, AF15q14 and a novel gene MPFYVE on chromosome 15.

KMT2A KNL1

6.37e-053161212618766
Pubmed

LRRC19 expressed in the kidney induces TRAF2/6-mediated signals to prevent infection by uropathogenic bacteria.

MYD88 LRRC19

6.37e-053161225026888
Pubmed

Dampening of IFN-gamma-inducible gene expression in human choriocarcinoma cells is due to phosphatase-mediated inhibition of the JAK/STAT-1 pathway.

STAT1 JAK2

6.37e-053161217237409
Pubmed

Sirtuin 2-mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses.

STAT1 SIRT2

6.37e-053161230487288
Pubmed

SYMPTOM SEVERITY IN SCHIZOPHRENIA PATIENTS WITH NPAS3, DYSBINDIN-1 AND/OR TRIOBP PROTEIN PATHOLOGY IN THEIR BLOOD SERUM: A PANSS-BASED FOLLOW UP STUDY.

NPAS3 TRIOBP

6.37e-053161237480305
Pubmed

ERK1/2 regulates SIRT2 deacetylase activity.

SIRT2 MAPK3

6.37e-053161223806683
Pubmed

Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection.

MYD88 ITGAX

6.37e-053161226627460
Pubmed

Association of CATSPER1, SPATA16 and TEX11 genes polymorphism with idiopathic azoospermia and oligospermia risk in Iranian population.

TEX11 SPATA16

6.37e-053161235248021
Pubmed

The JAK/STAT pathway is involved in the upregulation of PD-L1 expression in pancreatic cancer cell lines.

STAT1 JAK2

6.37e-053161228112370
Pubmed

Depletion of Suds3 reveals an essential role in early lineage specification.

SUDS3 MAPK3

6.37e-053161223123966
Pubmed

Autophagy is dispensable for Kmt2a/Mll-Mllt3/Af9 AML maintenance and anti-leukemic effect of chloroquine.

RB1CC1 KMT2A

6.37e-053161228282266
Pubmed

The angiotensin II-dependent nuclear translocation of Stat1 is mediated by the Jak2 protein motif 231YRFRR.

STAT1 JAK2

6.37e-053161211152457
Pubmed

JAK2 and PD-L1 Amplification Enhance the Dynamic Expression of PD-L1 in Triple-negative Breast Cancer.

STAT1 JAK2

6.37e-053161229933930
Pubmed

Plexin-A4-semaphorin 3A signaling is required for Toll-like receptor- and sepsis-induced cytokine storm.

MYD88 PLXNA4

6.37e-053161221098092
Pubmed

CD11c-mediated deletion of Flip promotes autoreactivity and inflammatory arthritis.

ITGAX CFLAR

6.37e-053161225963626
Pubmed

Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota.

MYD88 STAT1

6.37e-053161227879260
Pubmed

Direct stimulation of tlr5+/+ CD11c+ cells is necessary for the adjuvant activity of flagellin.

MYD88 ITGAX

6.37e-053161219494277
Pubmed

Advanced-glycation-end-product-induced formation of immunoproteasomes: involvement of RAGE and Jak2/STAT1.

STAT1 JAK2

6.37e-053161222892029
Pubmed

Angiotensin II Regulates Dendritic Cells through Activation of NF-κB /p65, ERK1/2 and STAT1 Pathways.

STAT1 MAPK3

6.37e-053161228723692
Pubmed

Inhibition of Jak/STAT signaling ameliorates mice experimental nephrotic syndrome.

STAT1 JAK2

6.37e-053161217823504
Pubmed

Autophagy facilitates IFN-gamma-induced Jak2-STAT1 activation and cellular inflammation.

STAT1 JAK2

6.37e-053161220592027
Pubmed

Primary cilia biogenesis and associated retinal ciliopathies.

CCP110 CEP290

6.37e-053161232747192
Pubmed

RNA immunoprecipitation identifies novel targets of DAZL in human foetal ovary.

TEX11 SMC1B

6.37e-053161228364521
Pubmed

Tip60 is regulated by circadian transcription factor clock and is involved in cisplatin resistance.

KAT5 HAT1

6.37e-053161218458078
Pubmed

Probucol inhibits JAK2-STAT pathway activation and protects human glomerular mesangial cells from tert-butyl hydroperoxide induced premature senescence.

STAT1 JAK2

6.37e-053161223984931
Pubmed

Genetic variation in the JAK/STAT/SOCS signaling pathway influences breast cancer-specific mortality through interaction with cigarette smoking and use of aspirin/NSAIDs: the Breast Cancer Health Disparities Study.

STAT1 JAK2

6.37e-053161225104439
Pubmed

Rare variants in MYD88, IRAK4 and IKBKG and susceptibility to invasive pneumococcal disease: a population-based case-control study.

MYD88 IKBKG

6.37e-053161225886387
Pubmed

Cigarette smoke extract promotes human vascular smooth muscle cell proliferation and survival through ERK1/2- and NF-κB-dependent pathways.

IKBKG MAPK3

6.37e-053161221057728
Pubmed

Distinct effects of V617F and exon12-mutated JAK2 expressions on erythropoiesis in a human induced pluripotent stem cell (iPSC)-based model.

STAT1 JAK2

6.37e-053161233664283
Pubmed

Constitutive JAK2/STAT1 activation regulates endogenous BACE1 expression in neurons.

STAT1 JAK2

6.37e-053161219508864
Pubmed

Clinical and molecular findings in a cohort of 152 Brazilian severe early onset inherited retinal dystrophy patients.

RPGRIP1 CEP290

6.37e-053161232865313
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CUL4B KAT5 TTC28 ARHGAP23 NET1 CUL9 RREB1 SH3TC1 SUDS3 SAP30BP MACF1 ZFHX3 TAF5L PRDM16 UNC80 KNL1

6.60e-0511161611631753913
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

ANKRD35 EPRS1 KAT5 ELP1 MDK ATP13A2 ITFG1 SYNE2 PDE4DIP SAP30BP EIF4G1 TAOK1 YY1AP1 TAF5L MAPK3 CCDC136

7.18e-0511241611621900206
Pubmed

A conserved acetylation switch enables pharmacological control of tubby-like protein stability.

HAT1 LANCL1 COPS3 WDR19 ARIH2 PDE4DIP MAPK3

8.57e-05223161733187986
Pubmed

The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly.

CCP110 CEP290 CROCC

8.93e-0519161324421332
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

ANKRD62 DST MACF1

1.05e-0420161321689717
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

EPRS1 RPL28 KRT9 CNTRL COPS3 SPAG5 DST EIF4G1 KMT2A MACF1 ZFHX3 NNT TARS1

1.05e-048071611330575818
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

RPL28 SHMT1 LANCL1 COPS3 RREB1 SYNE2 YY1AP1 TAF5L PRDM16

1.06e-04398161935016035
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

EPRS1 SIN3B RPL28 PCGF1 KAT5 RSL1D1 SMCHD1 CEP290 NUP88 HEATR1 RREB1 DST SUDS3 SAP30BP KMT2A SNU13 TAF5L

1.12e-0412941611730804502
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

EPRS1 RPL28 DNAH10 RSL1D1 SMCHD1 NUP88 ELP1 HAT1 LANCL1 COPS3 HEATR1 STAT1 EIF4G1 SNU13 TAF5L NNT TARS1 MCOLN2

1.14e-0414251611830948266
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

CCP110 RSL1D1 DST SNX25 MACF1 PRDM16 UTY

1.16e-04234161736243803
Pubmed

PDGF-BB induces PRMT1 expression through ERK1/2 dependent STAT1 activation and regulates remodeling in primary human lung fibroblasts.

STAT1 MAPK3

1.27e-044161226795953
Pubmed

Mycobacterial hypersensitivity pneumonitis requires TLR9-MyD88 in lung CD11b+ CD11c+ cells.

MYD88 ITGAX

1.27e-044161221273385
InteractionSYCE1 interactions

KAT5 CNTRL TXNDC11 SPAG5 RABGAP1L CROCC BFSP2 CCDC136 IQUB

7.56e-071271599int:SYCE1
InteractionPHF21A interactions

CUL4B SIN3B TTC28 NUP88 IKBKG RB1CC1 RREB1 SPAG5 DST RABGAP1L ZFHX3 DIAPH3 KNL1

3.47e-0634315913int:PHF21A
InteractionCCDC8 interactions

EPRS1 RPL28 KRT78 KAT5 SMCHD1 CEP290 ELP1 CUL9 HEATR1 RB1CC1 STAT1 DST EIF4G1 MACF1 SCIN NNT LARGE1

1.76e-0565615917int:CCDC8
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

SPAG1 TTC28 TRANK1 SH3TC1 UTY NAA16

3.80e-05115986769
GeneFamilyEF-hand domain containing|Plakins

DST MACF1

7.97e-048982939
GeneFamilyCullins

CUL4B CUL9

7.97e-0489821032
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

SIN3B SUDS3

1.02e-0399821306
CoexpressionRATTENBACHER_BOUND_BY_CELF1

CUL4B MYD88 FNDC3B STON1 RREB1 NLGN4X SH3TC1 SUDS3 SRGAP3 KMT2A SNU13 PRDM16 NAA16

3.65e-0644416013M2505
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

CUL4B TDRD5 CCP110 SESTD1 ZWILCH NUP88 HAT1 CNKSR2 HEATR1 TEX11 TRANK1 SNX25 RABGAP1L DIAPH3 CCDC181 CCDC171 NLRP4 SMC1B NAA16 TDRD12

2.32e-0682015520gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasalpha beta T cells, T.ISP.Th, 4- 8+ TCR-/lo 24hi, Thymus, avg-3

TDRD5 CCP110 SESTD1 ZWILCH ARPP21 SHMT1 HAT1 RRM1 SPAG5 DIAPH3 GEN1 KNL1

5.83e-0541715512GSM399403_500
CoexpressionAtlasalpha beta T cells, T.DN4.Th, Lin-/lo CD25- CD44- CD28+, Thymus, avg-3

TDRD5 ZWILCH ARPP21 SHMT1 HAT1 RRM1 SPAG5 SNU13 DIAPH3 GEN1 KNL1

1.03e-0437615511GSM791154_500
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000

CUL4B TDRD5 CCP110 SEMA4D SESTD1 ZWILCH NUP88 SHMT1 HAT1 CNKSR2 HEATR1 TEX11 DIAPH3 NLRP4 SMC1B NAA16 TDRD12

1.10e-0482215517gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

EPRS1 ZWILCH RSL1D1 CEP290 NPAS3 HAT1 HEATR1 CFAP210 SPAG5 WDR19 RNFT2 TRIM9 SRGAP3 LMLN SYNE2 CCDC181 CCDC171 GEN1 KNL1

1.12e-0498915519Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

EPRS1 TRAPPC11 CEP290 NPAS3 MYNN CFAP210 RB1CC1 SPAG5 ZNF546 WDR19 TRIM9 LMLN SYNE2 CCDC181 CCDC171 GEN1 KNL1

1.25e-0483115517Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasB cells, preB.FrD.FL, AA4.1+ IgM- CD19+ CD43- CD24+, Fetal Liver, avg-3

ZWILCH ARPP21 STON1 GPAM RRM1 TXNDC11 SPAG5 BFSP2 NNT GEN1 KNL1

1.59e-0439515511GSM538340_500
CoexpressionAtlasalpha beta T cells, preT.DN3-4.Th, Lin-/lo CD25int CD44- CD28+, Thymus, avg-3

TDRD5 ZWILCH ARPP21 SHMT1 HAT1 RRM1 SPAG5 SNU13 DIAPH3 GEN1 KNL1

1.66e-0439715511GSM791143_500
CoexpressionAtlasB cells, proB.FrBC.FL, CD19+ IgM- CD43+ CD24+ AA4.1+ CD45R+, Fetal Liver, avg-3

ZWILCH ARPP21 SHMT1 HAT1 GPAM RRM1 SPAG5 DIAPH3 BFSP2 GEN1 KNL1

1.77e-0440015511GSM538358_500
CoexpressionAtlasdev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#4_top-relative-expression-ranked_1000

FNDC3B SIN3B STON1 AGPAT4 RREB1 TRANK1 DST VNN1 LMLN SYNE2 CCDC171 UTY

1.94e-0447415512gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k4_1000
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCP110 SPAG1 CFAP210 DIAPH3 CCDC181 CCDC171 CCDC180 SMC1B

3.13e-0718016180c146e80d55d18b6988dd21b1da635801bd3140c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCP110 SPAG1 CFAP210 DIAPH3 CCDC181 CCDC171 CCDC180 SMC1B

3.13e-071801618e9af22beae2f3c7fe213b4e19df84abfd2453433
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCP110 SPAG1 CFAP210 DIAPH3 CCDC181 CCDC171 CCDC180 SMC1B

3.13e-07180161811455ba704ac73f69b474845136cfecec6a88349
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

SMCHD1 STAT1 CFLAR TRANK1 DST RABGAP1L SYNE2 TAOK1

3.55e-0718316188f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 RAD51AP2 DST ABCA5 KMT2A MACF1 UTY UNC80

5.74e-0719516187796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellBAL-Mild-cDC_1|Mild / Compartment, Disease Groups and Clusters

MYD88 SEMA4D SMCHD1 ITGAX JAK2 ANKRD22 RABGAP1L SCIN

6.70e-071991618c55181bdec8952b54198f0d4c9c5c84265b16572
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CCP110 ZWILCH CNTRL SPAG5 SYNE2 DIAPH3 GEN1 KNL1

6.70e-07199161898575fcce726589e93fbb4df1aab03e57cb56076
ToppCellmild-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NET1 ITGAX JAK2 CD1E DST SRGAP3 ZFHX3 MCOLN2

6.95e-07200161886f585bf9066b179bbcbc703bf43f15da4a07284
ToppCellfacs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPGRIP1 FNDC3B NET1 ITGAX ABCA5 SRGAP3 SCN3A

3.02e-0617116176a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCellfacs-Marrow-T-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPGRIP1 FNDC3B NET1 ITGAX ABCA5 SRGAP3 SCN3A

3.02e-061711617e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCellASK452-Immune-B_cell|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

LRRC37A3 LRRC37A2 SHMT1 SPAG5 ZNF546 PLXNA4 MCOLN2

3.39e-06174161769723f5666abc3af5f0431901a60246c9915ef81
ToppCellfacs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPGRIP1 NET1 ITGAX ABCA5 SRGAP3 SCN3A LARGE1

3.65e-06176161774f851a398c7562dd713bc0d8d488c0037243112
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TDRD5 NLRP7 TOPAZ1 BFSP2 NLRP4 SMC1B TDRD12

3.65e-061761617d5cee483d2a60f82fdc67ad447b589d022fe8c97
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CCDC125 EFCAB13 ELP1 GPAM ACSM3 ABCA5 PRDM16

3.65e-0617616171e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCellfacs-Marrow-T_cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPGRIP1 NET1 ITGAX ABCA5 SRGAP3 SCN3A LARGE1

3.65e-06176161731b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-progenitor-Germ|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TDRD5 NLRP7 TOPAZ1 BFSP2 NLRP4 SMC1B TDRD12

3.65e-061761617eea554ea75580f8dd5fefb57e7f33441ab86b884
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP23 NPAS3 FRY DST SNX25 PDE4DIP LARGE1

5.07e-0618516179197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP23 NPAS3 FRY DST SNX25 PDE4DIP LARGE1

5.07e-061851617ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VTCN1 SRGAP3 SCN3A ATP6V1C2 SCIN PRDM16 IQUB

5.07e-0618516173d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP23 NPAS3 FRY DST SNX25 PDE4DIP LARGE1

5.07e-061851617b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VTCN1 FRY SRGAP3 SCN3A SCIN PRDM16 IQUB

5.44e-061871617f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VTCN1 FRY SRGAP3 SCN3A SCIN PRDM16 IQUB

5.84e-0618916178ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellCF-Lymphoid-B_cell|CF / Disease state, Lineage and Cell class

CNTRL NUP88 SNX25 SCN3A GEN1 MCOLN2 LARGE1

6.04e-061901617374d8fd63c733178acab07682ed1519693efab45
ToppCellrenal_medulla_nuclei-Adult_normal_reference|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC37A3 RREB1 CFLAR FRY SNX25 PDE4DIP PRDM16

6.04e-061901617f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

FNDC3B SESTD1 NPAS3 ACSM3 NLGN4X TRIM9 ZFHX3

6.04e-06190161712992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellBAL-Mild|BAL / Compartment, Disease Groups and Clusters

STAT1 ANKRD22 TRANK1 RABGAP1L TAOK1 SCIN MCOLN2

6.47e-0619216171a6cbf014d3f7a3fb6f53adab078c4742e7137de
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 RAD51AP2 DST KMT2A MACF1 UTY UNC80

7.16e-0619516173e519cffa6144a62b06124642a14c9ff39b76554
ToppCellBasal_cells|World / lung cells shred on cell class, cell subclass, sample id

ARHGAP23 CYP24A1 MDK LHX6 DST SRGAP3 SYNE2

7.65e-06197161724360b660000bdfb999d58fbf4e29585a97e1785
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 CEP290 CFAP210 LMLN SYNE2 CCDC180 IQUB

7.65e-06197161774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

SMCHD1 SHMT1 STAT1 TRANK1 LRRC37A SYNE2 MACF1

7.91e-061981617ee71543559836fd59adc0da877b2ca538cba60cb
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

SPAG1 CNTRL CEP290 CFAP210 RB1CC1 LMLN SYNE2

8.17e-06199161761b1ed2db71b96157b92b7535d1955a4033098da
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

FNDC3B TTC28 LRRC37A3 VPS54 RABGAP1L FER UTY

8.17e-06199161794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T|COVID-19_Mild / Disease, condition lineage and cell class

SESTD1 CNTRL STAT1 TRANK1 TRIM9 SYNE2 MACF1

8.17e-061991617f307d4887b28cf60a591439e278fd668409cb104
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

SIN3B GBP6 SMCHD1 CFLAR SYNE2 KMT2A MACF1

8.45e-062001617edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

GBP6 SMCHD1 FRY DST SYNE2 MACF1 MAPK3

8.45e-06200161779e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellVE|World / Condition, Cell_class and T cell subcluster

SEMA4D SMCHD1 STAT1 TRANK1 SYNE2 KMT2A MACF1

8.45e-0620016178ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellcontrol-cDC|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ITGAX JAK2 CD1E DST SRGAP3 ZFHX3 MCOLN2

8.45e-0620016174a6d17a4225be38537d3dd8a39512051f597f4e0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZWILCH LHX6 NLGN4X ABCA5 ATP6V1C2 SCIN

1.93e-051521616655d47efe0608d729801f1f01668e84c1bc0675f
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZWILCH AGPAT4 ITGAX FRY DIAPH3 GEN1

2.40e-05158161691d265e95156f16459924d3e4dd11c180e164eee
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Otof-Sorcs1_(eccentric_SPN,_dSPN-like_markers)|Striatum / BrainAtlas - Mouse McCarroll V32

TDRD5 VTCN1 LRRC19 SPATA16

2.50e-05471614eef028d66c49406e71387e59bf7dddf5d5247472
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Otof-Sorcs1_(eccentric_SPN,_dSPN-like_markers)-|Striatum / BrainAtlas - Mouse McCarroll V32

TDRD5 VTCN1 LRRC19 SPATA16

2.50e-054716146420abf8a0094a1de6dea0670d5820b99edff78d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HYAL4 ANKRD22 SH3TC1 ABCA5 ATP6V1C2 SCIN

2.57e-051601616174a4ab27114efcc63be36929b80680be3c35c9b
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AGPAT4 ERI1 ITGAX THAP9 JAK2 VNN1

2.57e-0516016165d8d97c3da5837ba5fe743d2f8438f5cb7cea64b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HYAL4 ANKRD22 SRGAP3 ATP6V1C2 SCIN PRDM16

2.66e-051611616176a4a72bb4892932da3c834d1fea5e211847f92
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HYAL4 ANKRD22 SH3TC1 ABCA5 ATP6V1C2 SCIN

2.96e-05164161683141be8dfed85511ea6afda7c76ff4b6b5ef021
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HYAL4 ANKRD22 SH3TC1 SCN3A ATP6V1C2 SCIN

3.16e-0516616166fe8db8d45177a78605681f22e04fa8d0594f2df
ToppCellICU-SEP-Lymphocyte-T_NK-dnT|ICU-SEP / Disease, Lineage and Cell Type

RPGRIP1 LRRC37A2 GPAM ATP6V1C2 BFSP2 KNL1

3.16e-05166161696d92316cee20b722fe782db9dafcceb8f2c220b
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GPAM RAD51AP2 LMLN CCDC181 CROCC IQUB

3.38e-0516816169a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCP110 TTC28 ARHGAP23 SRGAP3 FER DIAPH3

3.38e-051681616b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

NET1 DCST1 ITGAX VNN1 SRGAP3 PRDM16

3.86e-051721616200b2e63313b110b8ca59ee5b72c02cc8ed907cd
ToppCelldroplet-Lung-nan-21m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZWILCH SHMT1 ITGAX JAK2 SRGAP3 KNL1

3.99e-0517316162eb6e9fc3a3654f6f86fbd112e80a18814afd103
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZWILCH SHMT1 ITGAX SPAG5 SRGAP3 KNL1

3.99e-0517316166c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZWILCH RRM1 ITGAX SPAG5 DIAPH3 KNL1

4.12e-05174161665147b0f8c2ccadd5685430d31081520c157536a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HYAL4 SCN3A ATP6V1C2 SCIN PRDM16 IQUB

4.53e-051771616f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCellCOVID-19_Mild-NK_CD56bright|COVID-19_Mild / Disease condition and Cell class

SPAG1 ITGAX DST SRGAP3 PLXNA4 ZFHX3

4.82e-05179161690e7a4af195aa2332b07a9f06cde63e72ff49255
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPAS3 STAT1 FRY SCN3A PRDM16 IQUB

4.82e-051791616d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPGRIP1 NET1 ITGAX ABCA5 SRGAP3 SCN3A

4.97e-051801616bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCellfacs-Marrow-B-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPGRIP1 NET1 ITGAX ABCA5 SRGAP3 SCN3A

4.97e-051801616839defb40f7cfb2711e9025194de636533f51bcd
ToppCellfacs-Marrow-B-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPGRIP1 NET1 ITGAX ABCA5 SRGAP3 SCN3A

4.97e-05180161682965ed1b72a1873c24dd4553d39681596057316
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KRT78 RRM1 ITGAX SPAG5 DIAPH3 KNL1

5.29e-05182161621dcab170ffeef89faa9fee5008568cb6e15c694
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Deuterosomal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DNAH10 GAS8 CFAP210 CCDC181 CCDC180 IQUB

5.29e-051821616000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EFCAB13 NPAS3 FRY SNX25 PDE4DIP LARGE1

5.62e-0518416167294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NET1 TOPAZ1 RRM1 ITGAX SPAG5 KNL1

5.79e-05185161657c1eb50a4456d20953e48d5dc3b0ea3d0d81b6d
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

EPRS1 SMCHD1 HEATR1 MACF1 UTY MCOLN2

5.79e-051851616a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

SPAG5 RNFT2 DIAPH3 BFSP2 GEN1 KNL1

5.79e-0518516169766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD22 DST ABCA5 ATP6V1C2 PRDM16 PLEKHA8

5.96e-051861616a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP3 SCN3A ATP6V1C2 SCIN PRDM16 IQUB

6.14e-0518716162d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SMCHD1 RB1CC1 SYNE2 KMT2A MACF1 TAOK1

6.33e-051881616ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

DNAH10 NET1 CEP290 CFAP210 CCDC181 CCDC180

6.33e-0518816168f30535a32968a81a304315a49c0d90a77d36948
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD22 DST ABCA5 ATP6V1C2 SCIN PRDM16

6.33e-051881616e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC3B SESTD1 DST VNN1 SYNE2 DIAPH3

6.52e-0518916168c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC3B SESTD1 DST VNN1 SYNE2 DIAPH3

6.52e-0518916165d902a4660a27548764bf04c6de152b565da835c
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCP110 SPAG1 MDK CCDC181 CCDC171 KNL1

6.71e-0519016160adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCP110 SPAG1 MDK CCDC181 CCDC171 KNL1

6.71e-05190161605455775845f4ded5c27e7b83242078d23162aaf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VTCN1 FRY SRGAP3 SCIN PRDM16 IQUB

6.71e-051901616b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FNDC3B KAT5 NET1 RRM1 GEN1 KNL1

6.71e-0519016163f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

OSTM1 SMCHD1 HEATR1 MACF1 UTY MCOLN2

6.91e-0519116169454f642c3621370fa23640b631301346b300950
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPAS3 FRY TRIM9 SCIN PRDM16 MCOLN2

6.91e-051911616273c4a757292a9301de0eaeacdec91c9866be229
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPAS3 FRY TRIM9 SCIN PRDM16 MCOLN2

6.91e-051911616f9a46956778a8773d6656340ecf5d218376d79c2
ToppCellrenal_papilla_nuclei-Adult_normal_reference|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC37A3 FRY SRGAP3 PDE4DIP PLXNA4 UTY

7.11e-0519216166c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERI1 RRM1 SPAG5 DIAPH3 GEN1 KNL1

7.11e-051921616e8d47504b744040a762ec9b670a66cc060b2ae86
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC3B TTC28 RABGAP1L SYNE2 MACF1 LARGE1

7.11e-051921616e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FNDC3B KAT5 NET1 RRM1 GEN1 KNL1

7.11e-051921616c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCellSevere_COVID-19-Myeloid-proliferating_Myeloid_cells|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

RRM1 SPAG5 DST DIAPH3 GEN1 KNL1

7.31e-0519316160d85025690c9cd545cba30abc38acbdd6a39b153
ToppCellCOVID-19-kidney-CD-PC|kidney / Disease (COVID-19 only), tissue and cell type

VTCN1 FRY SRGAP3 SCIN PRDM16 IQUB

7.31e-051931616738689d009e4b118d7ce3171a207294b95cbe78b
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

FNDC3B SESTD1 NPAS3 ACSM3 NLGN4X ZFHX3

7.31e-051931616dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellControl-NK_CD56bright|Control / Disease condition and Cell class

SPAG1 ITGAX DST SRGAP3 PLXNA4 ZFHX3

7.31e-0519316168b1e7a226a6057e1097c1525984127b54e823876
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

SESTD1 ITGAX SNX25 FER GEN1 LARGE1

7.31e-0519316167ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RRM1 SPAG5 DST DIAPH3 GEN1 KNL1

7.53e-051941616cb39850e9577015b6b9834e98c36b412bae7d462
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RRM1 SPAG5 DST DIAPH3 GEN1 KNL1

7.53e-051941616408597c9aa302a44b112c1d612c21fbb0227a82a
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RRM1 SPAG5 DST DIAPH3 GEN1 KNL1

7.53e-051941616193cc20fefbd795a4ad59e401a95af47d30603e7
ToppCellBAL-Severe-Myeloid-Myeloid|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RRM1 SPAG5 DST DIAPH3 GEN1 KNL1

7.53e-0519416162360b5f995b360419de41612368cab9fb61781a1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANKRD35 NLRP7 SIRT2 SYNE2 MACF1 MCOLN2

7.53e-05194161624837a27b0041fe8c348225fa8b09b127d743603
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RRM1 SPAG5 DST DIAPH3 GEN1 KNL1

7.53e-051941616903ae11708b0cb24538c6982abd57fe6fa95b8d3
ToppCellBAL-Severe-Myeloid-Myeloid|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RRM1 SPAG5 DST DIAPH3 GEN1 KNL1

7.53e-05194161658406502a8cbcc3037f79a1b6a683df408297ae5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD22 ABCA5 ATP6V1C2 SCIN NNT UNC80

7.74e-051951616f7d9adadd37209ce1a38e5d621607b9c9270fed8
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

SMCHD1 TRANK1 DST SYNE2 PDE4DIP KMT2A

7.74e-05195161622191d361af136942508f1553ff41a626ed982ad
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B1|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

STON1 DNAH10 CD1E BFSP2 PRDM16

7.84e-0512116154765e6ec00b0cf10d08cbd738c68a51d21bfb625
ToppCellBAL-Mild|BAL / Location, Disease Group, Cell group, Cell class (2021.03.09)

RPL28 MDK TRANK1 RABGAP1L TAOK1 MCOLN2

7.96e-0519616166566e6671257f7df4d3f375e84f0b292ab4bcde1
ToppCellMild-CD8+_T_activated|World / Disease group and Cell class

MYD88 SMCHD1 STAT1 TRANK1 TAOK1 MCOLN2

7.96e-05196161679632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

EPRS1 FNDC3B CFLAR DST KMT2A

4.22e-0549865GAVISH_3CA_MALIGNANT_METAPROGRAM_41_UNASSIGNED
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

SMCHD1 DST SYNE2 KMT2A MACF1

4.65e-0550865GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Drugalpha-estradiol; Up 200; 0.01uM; MCF7; HG-U133A

CNTRL GAS8 STAT1 CFLAR SIRT2 RNFT2 ZNF277 SRGAP3 MAPK3 NNT

1.22e-0619815710762_UP
Diseasecolon adenocarcinoma (is_implicated_in)

MYD88 STAT1 JAK2 MAPK3

9.75e-06261544DOID:234 (is_implicated_in)
DiseaseMalignant neoplasm of breast

FNDC3B NET1 CYP24A1 EFCAB13 LRRC37A2 SHMT1 ELP1 RB1CC1 STAT1 ZNF546 LRRC37A ZNF277 SRGAP3 SYNE2 MACF1 GEN1 PLEKHA8

4.88e-05107415417C0006142
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

SEMA4D KAT5 DNAH10 AGPAT4 GPAM SYNE2 MACF1

9.06e-052001547EFO_0004611, EFO_0020945
Diseasecup-to-disc ratio measurement

SESTD1 TTC28 EFCAB13 TRIOBP FAM76B RREB1 NPLOC4 KMT2A CCDC171 PRDM16

9.26e-0543015410EFO_0006939
Diseasehip bone mineral density, hip bone size

ABRA AGPAT4 NUP88 TRIOBP

2.12e-04561544EFO_0004844, EFO_0007702
Diseasewaist-hip ratio

FNDC3B VPS11 ARPP21 TTC28 DNAH10 SMCHD1 SHMT1 CUL9 RREB1 ATP13A2 SRGAP3 SYNE2 TAOK1 CCDC171 PRDM16 IQUB KNL1

2.39e-04122615417EFO_0004343
Diseaseobsolete_red blood cell distribution width

FNDC3B KAT5 TTC28 ARHGAP23 LRRC37A2 SHMT1 FAM76B ERI1 RRM1 ITGAX NPLOC4 TXNDC11 ITFG1 FIG4 RABGAP1L SYNE2 TAOK1 KNL1

2.44e-04134715418EFO_0005192
Diseaseliver cancer (is_implicated_in)

IKBKG JAK2

2.68e-0451542DOID:3571 (is_implicated_in)
Diseaseintraocular pressure measurement

ABRA FNDC3B NPAS3 TRIOBP ATP13A2 NPLOC4 FER KMT2A ZFHX3 PRDM16

3.59e-0450915410EFO_0004695
Diseasehip bone size

ABRA AGPAT4 NUP88 TRIOBP

3.77e-04651544EFO_0004844
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

SEMA4D KAT5 DNAH10 AGPAT4 GPAM SYNE2 MACF1

4.93e-042641547EFO_0008317, EFO_0020944
Diseasecaudate nucleus volume

NPAS3 ZFHX3 PRDM16

5.10e-04301543EFO_0004830
Disease3-hydroxypropylmercapturic acid measurement

TOPAZ1 NPAS3 GPAM CNKSR2 TXNDC11 SNX25 PLXNA4 KMT2A

5.47e-043521548EFO_0007014
DiseaseSenior-Loken syndrome (is_implicated_in)

CEP290 WDR19

5.59e-0471542DOID:0050576 (is_implicated_in)
DiseaseRenal dysplasia and retinal aplasia

CEP290 WDR19

5.59e-0471542cv:C0403553
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

FNDC3B SEMA4D DNAH10 SMCHD1 NUP88 MACF1 ZFHX3 CCDC171

6.80e-043641548EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseasereaction time measurement

TTC28 DNAH10 ARHGAP23 TOPAZ1 LRRC37A2 FAM76B FAM228B SRGAP3 RABGAP1L ZFHX3 CCDC171

7.06e-0465815411EFO_0008393
Diseasemyelofibrosis (is_implicated_in)

JAK2 KMT2A

7.42e-0481542DOID:4971 (is_implicated_in)
Diseasebody fat percentage

FNDC3B SEMA4D DNAH10 SMCHD1 NUP88 SRGAP3 MACF1 ZFHX3 CCDC171

1.10e-034881549EFO_0007800
Diseasevisceral adipose tissue measurement, body mass index

DNAH10 CNKSR2 RREB1 LARGE1

1.13e-03871544EFO_0004340, EFO_0004765
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

KAT5 AGPAT4 GPAM SYNE2 MACF1

1.17e-031501545EFO_0004611, EFO_0020947
Diseaseciliopathy (implicated_via_orthology)

RPGRIP1 CEP290 WDR19

1.20e-03401543DOID:0060340 (implicated_via_orthology)
Diseasepeak expiratory flow

FNDC3B STON1 RREB1 ATP13A2 FRY DST FIG4 CCDC171 NNT

1.27e-034981549EFO_0009718
DiseaseRenal dysplasia and retinal aplasia (disorder)

CEP290 WDR19

1.73e-03121542C0403553
Diseaseesophageal cancer (is_marker_for)

MYD88 CYP24A1

1.73e-03121542DOID:5041 (is_marker_for)
Diseaserotator cuff tear

SAP30BP CROCC

1.73e-03121542EFO_1001250
Diseasealpha fetoprotein measurement

SEMA4D SAP30BP GEN1 SMC1B

1.90e-031001544EFO_0010583
Diseasesexual dimorphism measurement

FNDC3B KRT9 KAT5 DNAH10 EFCAB13 GPAM DCST1 ATP13A2 TRANK1 FER MACF1 ZFHX3 MAPK3 CROCC

2.02e-03110615414EFO_0021796
DiseaseWeight Gain

SESTD1 RPL28 ZWILCH LARGE1

2.04e-031021544C0043094
Diseasefatty acid measurement

SEMA4D KAT5 AGPAT4 GPAM PLXNA4 KMT2A MACF1 CCDC171

2.13e-034361548EFO_0005110
Diseasecortical thickness

SEMA4D STON1 TRIOBP CUL9 RREB1 ATP13A2 STAT1 SRGAP3 SPATA16 KMT2A MACF1 DIAPH3 MAPK3 CCDC171

2.14e-03111315414EFO_0004840
Diseaselung adenocarcinoma (is_implicated_in)

CYP24A1 JAK2 ZFHX3

2.15e-03491543DOID:3910 (is_implicated_in)
Diseasebrain measurement, neuroimaging measurement

SEMA4D EFCAB13 TRIOBP RREB1 ATP13A2 MACF1 ZFHX3 MAPK3 PRDM16

2.48e-035501549EFO_0004346, EFO_0004464
DiseaseMeckel-Gruber syndrome

RPGRIP1 CEP290

2.72e-03151542C0265215
Diseasecancer (implicated_via_orthology)

SIN3B KAT5 DST SNU13 MACF1 MAPK3

2.91e-032681546DOID:162 (implicated_via_orthology)
Diseaseleukemia

CFLAR JAK2 KMT2A

3.00e-03551543C0023418
DiseaseLeber congenital amaurosis

RPGRIP1 CEP290

3.10e-03161542cv:C0339527
Diseasepancreatic ductal carcinoma (is_implicated_in)

HEATR1 MAPK3

3.10e-03161542DOID:3587 (is_implicated_in)
Diseasesystemic lupus erythematosus

TRAPPC11 STON1 CNKSR2 MYNN ERI1 ITGAX STAT1 JAK2 SRGAP3 RABGAP1L CCDC136

3.25e-0379915411MONDO_0007915
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

DNAH10 EFCAB13

3.50e-03171542EFO_0004611, EFO_0007800
Diseasesphingomyelin 14:0 measurement

SYNE2 ZFHX3

3.50e-03171542EFO_0010390
Diseaselevel of Sphingomyelin (d32:1) in blood serum

NUP88 SYNE2

3.50e-03171542OBA_2045173
Diseaseulcerative colitis (is_implicated_in)

CYP24A1 JAK2

3.50e-03171542DOID:8577 (is_implicated_in)
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

KAT5 GPAM SYNE2 MACF1

3.78e-031211544EFO_0008595, EFO_0020943
Diseasesmoking behavior, BMI-adjusted waist circumference

FNDC3B DNAH10 ATP13A2 FER

3.89e-031221544EFO_0004318, EFO_0007789
Diseasevelopharyngeal dysfunction

TTC28 NPAS3 RAD51AP2 C15orf32

3.89e-031221544EFO_0009336
DiseaseMeckel syndrome type 1

RPGRIP1 CEP290

3.92e-03181542C3714506
Diseaseglucose measurement

LRRC37A3 EFCAB13 ELP1 RREB1 LRRC37A TAOK1 PRDM16

3.92e-033801547EFO_0004468
Diseasemultiple sclerosis

KRT9 TTC28 CYP24A1 FAM76B MYNN RREB1 JAK2 ZFHX3 MAPK3

4.11e-035941549MONDO_0005301
Diseasep-tau:beta-amyloid 1-42 ratio measurement

KRT78 TTC28

4.37e-03191542EFO_0007709
Diseaseinsulin sensitivity measurement, body mass index

CYP24A1 NPAS3

4.37e-03191542EFO_0004340, EFO_0004471
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

KAT5 GPAM SYNE2 MACF1

4.49e-031271544EFO_0008595, EFO_0020947
Diseaseoptic disc size measurement

SESTD1 TRIOBP NPLOC4 MACF1 PRDM16

4.52e-032051545EFO_0004832
Diseasetea consumption measurement

ARPP21 CUL9 RABGAP1L ZFHX3

4.74e-031291544EFO_0010091

Protein segments in the cluster

PeptideGeneStartEntry
QLSLILSYECQISQK

TDRD5

931

Q8NAT2
NYLIKCRTKKSSVQE

ABCA5

21

Q8WWZ7
SKFLNIQCQLSRLKY

ERI1

236

Q8IV48
NEKRTLLQCETGKIY

FAM228B

166

P0C875
KQKTIELTRACQKQY

CNTRL

336

Q7Z7A1
KQCLSSLYKKNIQRL

COPS3

296

Q9UNS2
IVCQEYRKTSNKELR

ACER1

156

Q8TDN7
SKRLQYNEKSCSELQ

CCDC171

386

Q6TFL3
CHSLKYKQNNASRLI

FAM220BP

251

B1ANY3
ISEYKANKRCKSLQN

ANKRD62

256

A6NC57
QNAAKLLAKCRYTLQ

ARIH2

411

O95376
VNLKNQKERTCLHYA

ANKRD22

66

Q5VYY1
QELKALLEKYNTACR

ANKRD35

851

Q8N283
EKLSQRIQYLNCSLD

CCDC180

1181

Q9P1Z9
CAENISKKILEYQSQ

CCDC180

1416

Q9P1Z9
NKYENVDLLCKLENT

DIAPH3

671

Q9NSV4
LLARKCQLQKDVASY

BFSP2

391

Q13515
IVQQCKRTYLSQKSL

CBLL2

116

Q8N7E2
SLYLQCLSQKLRQER

CFLAR

421

O15519
EDSNICNETYKKRQL

ARPP21

316

Q9UBL0
SQNTCKRKDLISSNY

RAD51AP2

336

Q09MP3
QSNICLYIDKRSKNL

ITGAX

651

P20702
SQCKATARNLKLKYL

JAK2

241

O60674
YCSNQLAAKALLDQK

NET1

266

Q7Z628
NLEDCSNSYQKLLFK

RB1CC1

156

Q8TDY2
QYLDLSCNKIQSIER

LRRC37A3

916

O60309
KFRSNKQYRICLKTL

LARGE1

716

O95461
QYLDLSCNKIQSIER

LRRC37A2

916

A6NM11
QYLDLSCNKIQSIER

LRRC37A

916

A6NMS7
YVKQSLNCLTKRSIT

LANCL1

91

O43813
KSLEDTKNRYCGQLQ

KRT9

396

P35527
TLKKARYNAQCQETI

MDK

106

P21741
RSLYSKCNVLGNNLK

DST

4026

Q03001
LDKVLKNYDTICQIN

DST

5911

Q03001
LLSRQCATNQYLRKE

LMLN

141

Q96KR4
GRKNKSYSQNLCLLA

KAT5

306

Q92993
SNNKVVCTLRELNKY

FSIP2

126

Q5CZC0
LCQLSLSKLNTYALQ

FSIP2

1991

Q5CZC0
KQINDRIKERLQSCY

PLXNA4

361

Q9HCM2
QQSNLCKYFKDSRNI

NXF5

286

Q9H1B4
FTLRRLKYCQKNLLS

OR51A7

161

Q8NH64
SNLFKRILKCYEQKQ

NAA16

11

Q6N069
KCYRNALKLDKDNLQ

NAA16

101

Q6N069
KSQNYSQRRSIKDCL

FAM214A

756

Q32MH5
TKCQPSAITLNRQKY

NPLOC4

206

Q8TAT6
QTCLLTLRDYNNREK

MYNN

141

Q9NPC7
KQNLARLLCEYQELT

KRT78

386

Q8N1N4
QLEQTNYRLKLCVSD

MYD88

181

Q99836
CQALSTNYQIKKLDL

LRRC74A

211

Q0VAA2
KLLDLVQQSCNYKQL

SNU13

21

P55769
LQREYSKLKASCQES

IKBKG

336

Q9Y6K9
CTLSYKRVLQKTKEQ

FAM76B

131

Q5HYJ3
NLLLIQNKKLEDNYC

KNL1

116

Q8NG31
RTSLRQQNSCYIKNK

LHX6

101

Q9UPM6
SSVQYCQAKLNELSK

GBP6

401

Q6ZN66
CLNLIKDKNLYNEAL

ELP1

961

O95163
KLLKSQQLSNDHICY

MAPK3

131

P27361
LLTNNKKLTYLNVSC

NLRP4

746

Q96MN2
KKLTYLNVSCNQLDT

NLRP4

751

Q96MN2
RLYCDLLVQQVDKTK

PLEKHA8

121

Q96JA3
LLQTKNYSEVCKNCR

OSTM1

211

Q86WC4
FLRNLQDSIKRKYSC

MACF1

801

Q9UPN3
YKQICSQLSTRLEKQ

RABGAP1L

111

B7ZAP0
STYCLSPRQKELQKQ

CCDC181

331

Q5TID7
QNICKVLNRYLDIKE

CD1E

166

P15812
ICLSLYKTRKQSQTL

ATP13A2

271

Q9NQ11
LQYKKRCSELEQQLL

CROCC

181

Q5TZA2
KLAEYKCNTNTAIEL

HAT1

21

O14929
IQKYDRLNCENAVLK

CCDC125

201

Q86Z20
SVKACIDNRLEKYSQ

CYP24A1

281

Q07973
KYLLDQSQKESQCLK

CEP290

1691

O15078
ELKTKLRCSYVVNQA

DCST1

241

Q5T197
IKSDKEYASTLQNLC

FER

36

P16591
YTKSKLCNVLDRLNV

FIG4

421

Q92562
LTCTVKNLKRSTQYK

FNDC3B

531

Q53EP0
TDQCLIKYNLRLNLK

HYAL4

56

Q2M3T9
LEKNCSLQTELNKSY

CCP110

531

O43303
RKENSLCKLPNQYSV

EFCAB13

116

Q8IY85
LQKYLCDEQKELQAL

EIF4G1

1511

Q04637
QKRESFLKYKCLLQQ

IQUB

636

Q8NA54
QLSCESERYTANIKK

GEN1

631

Q17RS7
ATKQLLECNKCRNSY

KMT2A

1491

Q03164
KRYLCVTSLLDQLNS

CUL9

261

Q8IWT3
NRQTALYTLKLLCKN

HEATR1

1666

Q9H583
KKVAIYLCRNNTIQT

FRY

1476

Q5TBA9
INTYSKLLDEKTQCN

DNAH10

3026

Q8IVF4
ECLRNKNYKELIQQT

NLGN4X

316

Q8N0W4
KISANLYKQLRQICE

CUL4B

251

Q13620
EIKAKNLTNYDLCSI

MCOLN2

366

Q8IZK6
KREVQCNFTEKNYTL

LRRC19

26

Q9H756
DKNKSVLQNKYVRCS

PCGF1

181

Q9BSM1
LSAYQRKCIQSILKE

NUP88

706

Q99567
ELETLCQKRALQAYK

SHMT1

91

P34896
KTCDALQAKVRESYQ

NNT

1071

Q13423
RKALKLLCTSQNYGV

RNFT2

356

Q96EX2
CTLNKKIRNAQLAQY

TARS1

656

P26639
IRYLQSDNNTALCKV

TAF5L

176

O75529
QDAIKCYLNAARSKR

UTY

366

O14607
RLLSDKKQQYQTSCV

ATP6V1C2

266

Q8NEY4
NEAVECLLSLKAQYK

EPRS1

851

P07814
NNICCYKIRASLKRL

GFM2

21

Q969S9
SLQACNKRKKAQVYL

RPGRIP1

761

Q96KN7
DIEKLNQALCLRYKN

SPAG5

1026

Q96R06
NQALCLRYKNEKELQ

SPAG5

1031

Q96R06
QYRSAVCKLDSVNKD

SMCHD1

1911

A6NHR9
LQDEYDFKCKTLQNR

STAT1

166

P42224
ELKSQGNYLLECTKN

SYNE2

2201

Q8WXH0
QALITLKKNKESQYC

SYNE2

2506

Q8WXH0
SCNKYERLKANQVAT

SCIN

181

Q9Y6U3
KRYINQLTVAKKQCE

SNX25

241

Q9H3E2
YDEKNSCVKLLQFLN

TDRD12

366

Q587J7
LKHTLCRQAKNQAYA

PRDM16

1221

Q9HAZ2
SQEQLVRKAASLCYL

GPAM

611

Q9HCL2
LCSRLLKIYRQAQKQ

SIN3B

791

O75182
KDKGLLLRCYTQNID

SIRT2

156

Q8IXJ6
FQDTCKIQTRQYKAL

TAOK1

726

Q7L7X3
NLASIYRKQKNREKC

SH3TC1

606

Q8TE82
LQVALKDASSCYRQK

SPATA16

176

Q9BXB7
CNLKHLRLKTYETNL

NLRP7

931

Q8WX94
CESTYQNLQALRKEK

NPAS3

41

Q8IXF0
LNAAQLKKISDCTQY

WDR19

1321

Q8NEZ3
FRCYLLKQRLKNISS

SCN3A

1911

Q9NY46
GKSKQTECLNYIRVL

SEMA4D

101

Q92854
RNCSSFLIKRNKQTY

RPL28

11

P46779
NELQYLKKEVQCLRD

TRIOBP

2291

Q9H2D6
ELKSLQQQLSDVCYR

SESTD1

351

Q86VW0
RFTEKLNCKAQQKYS

ABRA

226

Q8N0Z2
QVLQTREKITTNCYK

ARNTL

391

O00327
LCTLQKKYDTSQDEQ

CCDC136

371

Q96JN2
QKDILYRLQSSKANC

ACSM3

156

Q53FZ2
AKQAKQAELDYCRLT

CFAP210

446

Q0VFZ6
QDTYNKAKCLALAQI

CLHC1

411

Q8NHS4
CLQQYIKNFEREKIS

CNKSR2

26

Q8WXI2
QVYQKLKTHLRCQSS

C15orf32

76

Q32M92
SCKADKNYSVNLENL

ZWILCH

171

Q9H900
SDKQILNIYDLCNKF

VPS11

306

Q9H270
CYLQKLKRQTSQVET

UNC80

2376

Q8N2C7
YAQERKQLAKTLCNH

TRAPPC11

356

Q7Z392
QERLSCLAKNNSIYV

VNN1

121

O95497
CKFLSDTQLNRYIEK

MIOS

621

Q9NXC5
KIDASQTCKQLYESL

MIX23

46

Q4VC31
IDQKSLNKCSLNYIC

STON1

216

Q9Y6Q2
ENKLKCTKARNDYLL

SRGAP3

231

O43295
VSKQRELYLQQKILC

THAP9

791

Q9H5L6
LLRAKRNSYTNCLQK

RREB1

1231

Q92766
DKITSRIQKLCYGLN

RRM1

16

P23921
HCKSRKNNYGLLLNE

RSL1D1

46

O76021
SIDQIYKKLCRNNSA

SMC1B

1076

Q8NDV3
CANQALISKKLNDYR

ARHGAP23

816

Q9P227
TLVFYCRKNKKRNSN

SPANXN4

51

Q5MJ08
KINNKECAIYTNRAL

SPAG1

651

Q07617
NLLSEKNVCKIYLSQ

ZNF546

141

Q86UE3
CYLNLQQLDKAKEAV

TEX11

466

Q8IYF3
RCSNHLQDKIQKLYE

SAP30BP

126

Q9UHR5
DRYQQSKAAALKCQL

TRIM9

156

Q9C026
CRTNKTLNIYLLDSN

TXNDC11

601

Q6PKC3
AEDNKYLLTCKTARQ

YY1AP1

306

Q9H869
KKYININELCLLQRA

TOPAZ1

1131

Q8N9V7
SKAEECQKYLLSLAQ

TTC28

691

Q96AY4
TLQKKLDNLQCLYCE

ZNF277

216

Q9NRM2
INKQLFRKINCRLSY

AGPAT4

41

Q9NRZ5
EDKNCQKSTIYLVRS

ITFG1

281

Q8TB96
KLADSIKAICNAYNR

TRANK1

906

O15050
YLESKDNQKLSCVIS

SUDS3

276

Q9H7L9
NVICQLLSDYKEKQI

POTEM

351

A6NI47
LALTRNNCVKVYNKL

VPS54

276

Q9P1Q0
RLKNVQLTDAGTYKC

VTCN1

116

Q7Z7D3
VLCNYSTKAKLNLIQ

ZFHX3

1091

Q15911
IRTSNLNYQCKKCSL

ZFHX3

2321

Q15911
LNYQCKKCSLVFQRI

ZFHX3

2326

Q15911
QLANYERDKQILLCT

GAS8

296

O95995
LRSQLSQCKQRYQDL

PDE4DIP

1216

Q5VU43
SQCKQRYQDLQEKLL

PDE4DIP

1221

Q5VU43