Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP hydrolysis activity	IFIH1 PMS2 ABCB10 SMC1A DHX38 MTREX SMC2 ABCD2 RAD50	1.67e-04	441	90	9	GO:0016887
GeneOntologyMolecularFunction	cAMP binding	PRKAR2B CNGA2 CNGA4	1.90e-04	25	90	3	GO:0030552
GeneOntologyMolecularFunction	histone H3K9me2/H3K9me3 demethylase activity	KDM4D KDM4E	2.98e-04	6	90	2	GO:0140684
GeneOntologyMolecularFunction	intracellularly cGMP-activated cation channel activity	CNGA2 CNGA4	4.16e-04	7	90	2	GO:0005223
GeneOntologyMolecularFunction	structural constituent of presynaptic active zone	ERC2 RIMS2	5.53e-04	8	90	2	GO:0098882
GeneOntologyMolecularFunction	tubulin binding	NUSAP1 DST BRCA1 IFT74 FAM161A LRRK2 NUMA1 GOLGA8B	6.98e-04	428	90	8	GO:0015631
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	IFIH1 HBS1L PMS2 ABCB10 SMC1A DHX38 LRRK2 MTREX SMC2 ABCD2 RAD50	7.15e-04	775	90	11	GO:0017111
GeneOntologyMolecularFunction	cyclic nucleotide binding	PRKAR2B CNGA2 CNGA4	7.20e-04	39	90	3	GO:0030551
GeneOntologyMolecularFunction	intracellularly cAMP-activated cation channel activity	CNGA2 CNGA4	8.83e-04	10	90	2	GO:0005222
GeneOntologyMolecularFunction	structural constituent of synapse	ERC2 POTEJ RIMS2	8.95e-04	42	90	3	GO:0098918
GeneOntologyMolecularFunction	pyrophosphatase activity	IFIH1 HBS1L PMS2 ABCB10 SMC1A DHX38 LRRK2 MTREX SMC2 ABCD2 RAD50	1.36e-03	839	90	11	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	IFIH1 HBS1L PMS2 ABCB10 SMC1A DHX38 LRRK2 MTREX SMC2 ABCD2 RAD50	1.37e-03	840	90	11	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IFIH1 HBS1L PMS2 ABCB10 SMC1A DHX38 LRRK2 MTREX SMC2 ABCD2 RAD50	1.37e-03	840	90	11	GO:0016818
GeneOntologyMolecularFunction	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	CNGA2 CNGA4	1.52e-03	13	90	2	GO:0005221
GeneOntologyMolecularFunction	cyclic nucleotide-activated monoatomic ion channel activity	CNGA2 CNGA4	1.52e-03	13	90	2	GO:0043855
GeneOntologyMolecularFunction	histone H3K9 demethylase activity	KDM4D KDM4E	1.76e-03	14	90	2	GO:0032454
GeneOntologyMolecularFunction	ATP-dependent activity	IFIH1 PMS2 ABCB10 SMC1A DHX38 MTREX SMC2 ABCD2 RAD50	1.79e-03	614	90	9	GO:0140657
GeneOntologyMolecularFunction	cGMP binding	CNGA2 CNGA4	2.31e-03	16	90	2	GO:0030553
GeneOntologyMolecularFunction	microtubule binding	NUSAP1 DST FAM161A LRRK2 NUMA1 GOLGA8B	2.70e-03	308	90	6	GO:0008017
GeneOntologyBiologicalProcess	meiotic cell cycle	ANKRD31 PMS2 MNS1 SMC1A NUMA1 ASPM GOLGA8B SMC2 ZNF541 RAD50	2.99e-06	350	90	10	GO:0051321
GeneOntologyBiologicalProcess	organelle fission	NUSAP1 ANKRD31 SMC1A LRRK2 NUMA1 ASPM GOLGA8B PINX1 SMC2 ZNF541 RAD50	3.83e-05	571	90	11	GO:0048285
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	NUSAP1 FSIP2 SRGAP2C DST BRCA1 MNS1 SMC1A SSX2IP NUMA1 ASPM GOLGA8B DEUP1	6.76e-05	720	90	12	GO:0000226
GeneOntologyBiologicalProcess	nuclear division	NUSAP1 ANKRD31 SMC1A NUMA1 ASPM GOLGA8B PINX1 SMC2 ZNF541 RAD50	7.87e-05	512	90	10	GO:0000280
GeneOntologyBiologicalProcess	organelle assembly	FSIP2 BRCA1 MNS1 IFT74 FAM161A CEP162 SMC1A SSX2IP LRRK2 NUMA1 ASPM GOLGA8B NEB PSPC1 DEUP1	1.13e-04	1138	90	15	GO:0070925
GeneOntologyBiologicalProcess	cell cycle process	NUSAP1 ANKRD31 MYBBP1A BRCA1 SMC1A SSX2IP NUMA1 ASPM GOLGA8B PINX1 SMC2 TRRAP ATF2 TXLNG ZNF541 DEUP1 RAD50	1.45e-04	1441	90	17	GO:0022402
GeneOntologyBiologicalProcess	nuclear chromosome segregation	NUSAP1 ANKRD31 SMC1A NUMA1 ASPM GOLGA8B PINX1 SMC2	1.65e-04	356	90	8	GO:0098813
GeneOntologyBiologicalProcess	chromosome segregation	NUSAP1 ANKRD31 BRCA1 SMC1A NUMA1 ASPM GOLGA8B PINX1 SMC2	1.95e-04	465	90	9	GO:0007059
GeneOntologyCellularComponent	mitotic spindle pole	FAM161A SMC1A NUMA1 ASPM	3.80e-05	43	92	4	GO:0097431
GeneOntologyCellularComponent	non-motile cilium membrane	CNGA2 CNGA4	5.73e-05	3	92	2	GO:0098804
GeneOntologyCellularComponent	nuclear chromosome	BRCA1 SMC1A PINX1 SMC2 TRRAP LRIF1 RAD50	1.31e-04	254	92	7	GO:0000228
GeneOntologyCellularComponent	mitotic spindle	NUSAP1 FAM161A SMC1A NUMA1 ASPM GOLGA8B	2.63e-04	201	92	6	GO:0072686
GeneOntologyCellularComponent	BRCA1-C complex	BRCA1 RAD50	2.84e-04	6	92	2	GO:0070533
GeneOntologyCellularComponent	intracellular cyclic nucleotide activated cation channel complex	CNGA2 CNGA4	3.97e-04	7	92	2	GO:0017071
GeneOntologyCellularComponent	microtubule minus-end	NUMA1 ASPM	3.97e-04	7	92	2	GO:0036449
GeneOntologyCellularComponent	cytoskeleton of presynaptic active zone	ERC2 RIMS2	5.27e-04	8	92	2	GO:0048788
GeneOntologyCellularComponent	microtubule end	DST NUMA1 ASPM	6.22e-04	38	92	3	GO:1990752
GeneOntologyCellularComponent	condensed nuclear chromosome	BRCA1 SMC1A SMC2 RAD50	7.01e-04	91	92	4	GO:0000794
GeneOntologyCellularComponent	catalytic step 2 spliceosome	MAGOH GPATCH1 DHX38 MTREX	8.91e-04	97	92	4	GO:0071013
GeneOntologyCellularComponent	nuclear periphery	SMC1A NUMA1 PSPC1 MNDA LRIF1	9.57e-04	171	92	5	GO:0034399
GeneOntologyCellularComponent	H4 histone acetyltransferase complex	POTEJ TRRAP ATF2	1.02e-03	45	92	3	GO:1902562
GeneOntologyCellularComponent	cell cortex region	NUMA1 ERC2 RIMS2	1.02e-03	45	92	3	GO:0099738
GeneOntologyCellularComponent	astral microtubule	FAM161A NUMA1	1.03e-03	11	92	2	GO:0000235
GeneOntologyCellularComponent	site of double-strand break	KDM4D KDM4E ATF2 RAD50	1.04e-03	101	92	4	GO:0035861
GeneOntologyCellularComponent	cytoplasmic region	DST MNS1 CEP162 LRRK2 NUMA1 ERC2 RIMS2	1.06e-03	360	92	7	GO:0099568
GeneOntologyCellularComponent	spindle	NUSAP1 FAM161A CEP162 SMC1A NUMA1 ASPM GOLGA8B PINX1	1.11e-03	471	92	8	GO:0005819
GeneOntologyCellularComponent	aster	FAM161A NUMA1	1.23e-03	12	92	2	GO:0005818
GeneOntologyCellularComponent	Golgi-associated vesicle	LRRK2 ERC2 CNGA2 CNGA4	1.62e-03	114	92	4	GO:0005798
GeneOntologyCellularComponent	presynaptic cytoskeleton	ERC2 RIMS2	1.68e-03	14	92	2	GO:0099569
GeneOntologyCellularComponent	spindle pole	FAM161A SMC1A NUMA1 ASPM GOLGA8B	2.13e-03	205	92	5	GO:0000922
GeneOntologyCellularComponent	condensed chromosome	BRCA1 SMC1A GPATCH11 PINX1 SMC2 RAD50	2.37e-03	307	92	6	GO:0000793
GeneOntologyCellularComponent	microtubule	NUSAP1 DST MNS1 FAM161A CEP162 NUMA1 ASPM GOLGA8B	2.42e-03	533	92	8	GO:0005874
GeneOntologyCellularComponent	chromosomal region	KDM4D SMC1A GPATCH11 PINX1 KDM4E LRIF1 RAD50	2.58e-03	421	92	7	GO:0098687
GeneOntologyCellularComponent	cytoplasmic microtubule	MNS1 FAM161A CEP162 NUMA1	2.84e-03	133	92	4	GO:0005881
GeneOntologyCellularComponent	lateral element	BRCA1 SMC1A	3.12e-03	19	92	2	GO:0000800
GeneOntologyCellularComponent	site of DNA damage	KDM4D KDM4E ATF2 RAD50	3.16e-03	137	92	4	GO:0090734
GeneOntologyCellularComponent	nuclear matrix	SMC1A NUMA1 PSPC1 LRIF1	3.41e-03	140	92	4	GO:0016363
GeneOntologyCellularComponent	presynaptic active zone cytoplasmic component	ERC2 RIMS2	4.56e-03	23	92	2	GO:0098831
Domain	RecF/RecN/SMC_N	SMC1A SMC2 RAD50	5.95e-06	8	90	3	IPR003395
Domain	SMC_N	SMC1A SMC2 RAD50	5.95e-06	8	90	3	PF02463
Domain	cNMP-bd_CS	PRKAR2B CNGA2 CNGA4	5.79e-05	16	90	3	IPR018488
Domain	CLZ_dom	CNGA2 CNGA4	1.37e-04	4	90	2	IPR032406
Domain	CLZ	CNGA2 CNGA4	1.37e-04	4	90	2	PF16526
Domain	G_patch	GPATCH1 GPATCH11 PINX1	1.79e-04	23	90	3	SM00443
Domain	G_patch_dom	GPATCH1 GPATCH11 PINX1	1.79e-04	23	90	3	IPR000467
Domain	G_PATCH	GPATCH1 GPATCH11 PINX1	1.79e-04	23	90	3	PS50174
Domain	G-patch	GPATCH1 GPATCH11 PINX1	1.79e-04	23	90	3	PF01585
Domain	P-loop_NTPase	IFIH1 GIMAP4 HBS1L ABCB10 SMC1A DHX38 LRRK2 ASPM IFI44L MTREX SMC2 ABCD2 RAD50	2.05e-04	848	90	13	IPR027417
Domain	SMC	SMC1A SMC2	2.27e-04	5	90	2	IPR024704
Domain	-	IFIH1 GIMAP4 HBS1L ABCB10 SMC1A DHX38 LRRK2 IFI44L MTREX SMC2 ABCD2 RAD50	2.37e-04	746	90	12	3.40.50.300
Domain	SMC_hinge	SMC1A SMC2	3.40e-04	6	90	2	PF06470
Domain	SMC_hinge	SMC1A SMC2	3.40e-04	6	90	2	SM00968
Domain	SMC_hinge	SMC1A SMC2	3.40e-04	6	90	2	IPR010935
Domain	CNMP_BINDING_1	PRKAR2B CNGA2 CNGA4	4.85e-04	32	90	3	PS00888
Domain	CNMP_BINDING_2	PRKAR2B CNGA2 CNGA4	4.85e-04	32	90	3	PS00889
Domain	cNMP	PRKAR2B CNGA2 CNGA4	5.81e-04	34	90	3	SM00100
Domain	cNMP_binding	PRKAR2B CNGA2 CNGA4	5.81e-04	34	90	3	PF00027
Domain	cNMP-bd_dom	PRKAR2B CNGA2 CNGA4	6.33e-04	35	90	3	IPR000595
Domain	CNMP_BINDING_3	PRKAR2B CNGA2 CNGA4	6.33e-04	35	90	3	PS50042
Domain	cNMP-bd-like	PRKAR2B CNGA2 CNGA4	8.08e-04	38	90	3	IPR018490
Domain	Leu-rich_rpt_4	LRRIQ3 LRRK2	1.01e-03	10	90	2	IPR025875
Domain	JmjN	KDM4D KDM4E	1.01e-03	10	90	2	SM00545
Domain	JMJN	KDM4D KDM4E	1.01e-03	10	90	2	PS51183
Domain	LRR_4	LRRIQ3 LRRK2	1.01e-03	10	90	2	PF12799
Domain	JmjN	KDM4D KDM4E	1.01e-03	10	90	2	PF02375
Domain	JmjN	KDM4D KDM4E	1.01e-03	10	90	2	IPR003349
Domain	-	PRKAR2B CNGA2 CNGA4	1.60e-03	48	90	3	2.60.120.10
Domain	RmlC-like_jellyroll	PRKAR2B CNGA2 CNGA4	1.91e-03	51	90	3	IPR014710
Domain	FCH	SRGAP2C PSTPIP2	4.98e-03	22	90	2	PF00611
Domain	Znf_C2H2_jaz	PRDM10 ZNF638	4.98e-03	22	90	2	IPR022755
Domain	zf-C2H2_jaz	PRDM10 ZNF638	4.98e-03	22	90	2	PF12171
Pathway	WP_SMC1SMC3_ROLE_IN_DNA_DAMAGE_CORNELIA_DE_LANGE_SYNDROME	BRCA1 SMC1A RAD50	1.57e-05	11	66	3	M42562
Pathway	WP_ATM_SIGNALING	BRCA1 SMC1A ATF2 RAD50	3.53e-05	40	66	4	M39433
Pathway	WP_DNA_IRDOUBLE_STRAND_BREAKS_AND_CELLULAR_RESPONSE_VIA_ATM	BRCA1 SMC1A ATF2 RAD50	1.25e-04	55	66	4	M39598
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	PPP1R2 RLF NUSAP1 PMS2 DST BRCA1 IFT74 CEP162 PSMB1 SSX2IP ZNF638 PINX1 TXLNG LRIF1 RAD50	1.58e-10	645	92	15	25281560
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	MYBBP1A PMS2 SMC1A GPATCH1 DHX38 ESRP1 ZNF638 GREB1 MTREX PSPC1 TRRAP	1.82e-09	341	92	11	32971831
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	HBS1L MYBBP1A DST IFT74 DHX38 NUMA1 PRKAR2B SMC2 PSPC1 GCN1 NOSIP RAD50	8.38e-09	498	92	12	36634849
Pubmed	TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin.	PMS2 BRCA1 SMC1A SMC2 RAD50	1.87e-08	31	92	5	26095369
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	RLF NUSAP1 EPRS1 BRCA1 SMC1A PSMB1 MTREX SMC2 PSPC1 TRRAP ATF2 TXLNG MNDA LRIF1 NOSIP RAD50	3.09e-08	1103	92	16	34189442
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	IVD FAM184B EPRS1 MYBBP1A DST BRCA1 FAM161A NUMA1 ASPM ERC2 ALAS2 POTEJ NEB SMC2 RIMS2 PSPC1 MNDA ZNF541	3.76e-08	1442	92	18	35575683
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	NUSAP1 EPRS1 MYBBP1A DST BRCA1 SMC1A GPATCH1 DHX38 NUMA1 ZNF638 MTREX SMC2 PC TRRAP ATF2 LRIF1 RAD50	4.56e-08	1294	92	17	30804502
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	MYBBP1A SMC1A NUMA1 ZNF638 POTEJ SMC2 PSPC1 GCN1 RAD50	4.58e-08	271	92	9	32433965
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	EPRS1 MYBBP1A GPATCH1 NUMA1 ZNF638 POTEJ GCN1 GOLGA3	6.91e-08	202	92	8	24639526
Pubmed	Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.	PMS2 BRCA1 FAM161A SMC1A SSX2IP NUMA1 RAD50	1.49e-07	149	92	7	25184681
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	MYBBP1A DST NUMA1 ASPM MTREX NEB PC RAD50	2.13e-07	234	92	8	36243803
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	EPRS1 HBS1L MTRF1 MYBBP1A IFT74 NUMA1 SMC2 PC TRRAP GCN1 RAD50	2.33e-07	549	92	11	38280479
Pubmed	NBS1 prevents chromatid-type aberrations through ATM-dependent interactions with SMC1.	BRCA1 SMC1A RAD50	3.56e-07	6	92	3	18763866
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	ARFGEF3 OTUD5 IFT74 DHX38 ASPM ERC2 POTEJ MTREX LRIF1 NOSIP RAD50	4.59e-07	588	92	11	38580884
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RLF EPRS1 HBS1L MYBBP1A DST SMC1A DHX38 PSMB1 NUMA1 ASPM ZNF638 MTREX SMC2 TRRAP GCN1 RAD50	4.89e-07	1353	92	16	29467282
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	RLF NUSAP1 FSIP2 BRCA1 NKX2-1 SMC1A NUMA1 GPATCH11 PINX1 TRRAP LRIF1	6.37e-07	608	92	11	36089195
Pubmed	Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners.	EPRS1 SMC1A LRRK2 MTREX RAD50	6.67e-07	62	92	5	26508657
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	NUSAP1 MYBBP1A SMC1A NUMA1 ASPM PINX1 ERC2 MTREX SMC2 TRRAP GCN1 TXLNG	7.88e-07	759	92	12	35915203
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	EPRS1 HBS1L MYBBP1A SMC1A DHX38 PSMB1 NUMA1 ZNF638 MTREX SMC2 PC PSPC1 GCN1 TXLNG NOSIP RAD50	8.83e-07	1415	92	16	28515276
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ARFGEF3 MYBBP1A DST AFF2 BRCA1 CEP162 GPATCH1 LRRK2 ZNF638 PC GCN1 GOLGA3	1.01e-06	777	92	12	35844135
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	HBS1L SMC1A DHX38 NUMA1 PINX1 MTREX SMC2 PSPC1 GCN1 TXLNG NOSIP	1.28e-06	653	92	11	33742100
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PPP1R2 EPRS1 MYBBP1A MAGOH CEP162 SMC1A DHX38 PSMB1 ASPM PINX1 MTREX SMC2 TRRAP GCN1 RAD50	1.36e-06	1284	92	15	17353931
Pubmed	Directed proteomic analysis of the human nucleolus.	MYBBP1A SMC1A NUMA1 MTREX PSPC1 GCN1 RAD50	1.41e-06	208	92	7	11790298
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	MYBBP1A SMC1A NUMA1 MTREX PSPC1 TRRAP RAD50	2.05e-06	220	92	7	35785414
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	HBS1L PRDM10 ABCB10 IFT74 SMC1A NUMA1 PRKAR2B MTREX SMC2 RAD50	2.39e-06	560	92	10	35241646
Pubmed	The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.	EPRS1 MYBBP1A SMC1A GPATCH1 NUMA1 POTEJ PC GCN1	2.81e-06	330	92	8	32529326
Pubmed	MDC1 is a mediator of the mammalian DNA damage checkpoint.	BRCA1 SMC1A RAD50	2.91e-06	11	92	3	12607005
Pubmed	SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint.	BRCA1 SMC1A RAD50	2.91e-06	11	92	3	11877377
Pubmed	Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes.	BRCA1 SMC1A RAD50	3.87e-06	12	92	3	16391231
Pubmed	BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.	PMS2 BRCA1 RAD50	3.87e-06	12	92	3	10783165
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	MYBBP1A SMC1A NUMA1 GPATCH11 ZNF638 SMC2 TRRAP GCN1 RAD50	4.41e-06	469	92	9	27634302
Pubmed	Repressive histone methylation regulates cardiac myocyte cell cycle exit.	KDM4D KDM4E	6.92e-06	2	92	2	29800554
Pubmed	NUSAP1 influences the DNA damage response by controlling BRCA1 protein levels.	NUSAP1 BRCA1	6.92e-06	2	92	2	24521615
Pubmed	Inherited BRCA1 and RNF43 pathogenic variants in a familial colorectal cancer type X family.	BRCA1 RNF43	6.92e-06	2	92	2	38063999
Pubmed	Kdm4d mutant mice show impaired sperm motility and subfertility.	KDM4D KDM4E	6.92e-06	2	92	2	39034148
Pubmed	Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling.	KDM4D KDM4E	6.92e-06	2	92	2	32094404
Pubmed	Mutation in FBXO32 causes dilated cardiomyopathy through up-regulation of ER-stress mediated apoptosis.	FBXO32 ATF2	6.92e-06	2	92	2	34272480
Pubmed	Histone Demethylase JMJD2D Interacts With β-Catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice.	KDM4D KDM4E	6.92e-06	2	92	2	30472235
Pubmed	Dystonin/Bpag1 is a necessary endoplasmic reticulum/nuclear envelope protein in sensory neurons.	SYNE3 DST	6.92e-06	2	92	2	18638474
Pubmed	The abnormal spindle-like, microcephaly-associated (ASPM) gene encodes a centrosomal protein.	BRCA1 ASPM	6.92e-06	2	92	2	16123590
Pubmed	Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling.	KDM4D KDM4E	6.92e-06	2	92	2	35027670
Pubmed	Embryonic development following somatic cell nuclear transfer impeded by persisting histone methylation.	KDM4D KDM4E	6.92e-06	2	92	2	25417163
Pubmed	CRL4-DCAF8L2 E3 ligase promotes ubiquitination and degradation of BARD1.	MYBBP1A BRCA1 NUMA1	7.96e-06	15	92	3	35487060
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	MYBBP1A MAGOH BRCA1 SMC1A NUMA1 ZNF638 MTREX SMC2 LRIF1 RAD50	9.08e-06	652	92	10	31180492
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	EPRS1 HBS1L MYBBP1A ABCB10 SMC1A DHX38 NUMA1 PRKAR2B MTREX SMC2 PC PSPC1 GCN1 LRIF1	9.37e-06	1318	92	14	30463901
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	MYBBP1A GPATCH1 DHX38 NUMA1 GPATCH11 ZNF638 PSPC1	1.06e-05	283	92	7	30585729
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	NUSAP1 MYBBP1A SMC1A DHX38 NUMA1 TTC14 ZNF638 PINX1 MTREX PC NOSIP RAD50	1.18e-05	989	92	12	36424410
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	EPRS1 MYBBP1A MAGOH SMC1A DHX38 NUMA1 ZNF638 MTREX SMC2 PSPC1 TRRAP	1.50e-05	847	92	11	35850772
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	NUSAP1 MYBBP1A SMC1A DHX38 PSMB1 NUMA1 MTREX SMC2 PSPC1 TRRAP NOSIP RAD50	1.51e-05	1014	92	12	32416067
Pubmed	Nucleolar proteome dynamics.	MYBBP1A SMC1A MTREX SMC2 PSPC1 GCN1 NOSIP RAD50	1.60e-05	419	92	8	15635413
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	EPRS1 MYBBP1A DST SMC1A NUMA1 ZNF638 MTREX SMC2 PSPC1 TRRAP GCN1 RAD50	1.66e-05	1024	92	12	24711643
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	MYBBP1A DHX38 NUMA1 MTREX SMC2 PC TRRAP GCN1 NOSIP RAD50	1.76e-05	704	92	10	29955894
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	PPP1R2 ARFGEF3 HBS1L DST SSX2IP GOLGA3	2.03e-05	209	92	6	36779422
Pubmed	Deficient nonhomologous end-joining activity in cell-free extracts from Brca1-null fibroblasts.	BRCA1 RAD50	2.07e-05	3	92	2	12124328
Pubmed	RAD50 germline mutations are associated with poor survival in BRCA1/2-negative breast cancer patients.	BRCA1 RAD50	2.07e-05	3	92	2	29726012
Pubmed	Association of BLM and BRCA1 during Telomere Maintenance in ALT Cells.	BRCA1 RAD50	2.07e-05	3	92	2	25084169
Pubmed	The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice.	KDM4D KDM4E	2.07e-05	3	92	2	21555854
Pubmed	ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control.	SMC1A RAD50	2.07e-05	3	92	2	21757780
Pubmed	Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer.	BRCA1 RAD50	2.07e-05	3	92	2	26824983
Pubmed	Histone demethylase JMJD2D protects against enteric bacterial infection via up-regulating colonic IL-17F to induce β-defensin expression.	KDM4D KDM4E	2.07e-05	3	92	2	38905308
Pubmed	The testis-enriched histone demethylase, KDM4D, regulates methylation of histone H3 lysine 9 during spermatogenesis in the mouse but is dispensable for fertility.	KDM4D KDM4E	2.07e-05	3	92	2	21293030
Pubmed	Importance of the CNGA4 channel gene for odor discrimination and adaptation in behaving mice.	CNGA2 CNGA4	2.07e-05	3	92	2	12649326
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PPP1R2 NUSAP1 MYBBP1A PMS2 CEP162 DHX38 SSX2IP ZNF638 PINX1 PSTPIP2 PC GCN1	2.10e-05	1049	92	12	27880917
Pubmed	HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.	EPRS1 HBS1L MYBBP1A SMC1A PSMB1 MTREX SMC2 GCN1 RAD50	2.11e-05	571	92	9	37167062
Pubmed	A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex.	MYBBP1A MTREX GOLGA3	2.30e-05	21	92	3	24923560
Pubmed	Human transcription factor protein interaction networks.	RLF NUSAP1 MYBBP1A MAGOH DST BRCA1 SMC1A PSMB1 NUMA1 ZNF638 TRRAP LRIF1 NOSIP RAD50	2.30e-05	1429	92	14	35140242
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	NUSAP1 EPRS1 MYBBP1A DST SMC1A DHX38 NUMA1 ZNF638 MTREX SMC2 PSPC1 NOSIP RAD50	2.66e-05	1257	92	13	36526897
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	NUSAP1 FAM184B EPRS1 HBS1L MYBBP1A PMS2 CEP162 DHX38 ESRP1 TTC14 ZNF638 ATF2	2.90e-05	1084	92	12	11544199
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	EPRS1 SMC1A NUMA1 ZNF638 SMC2 GCN1 RAD50	2.97e-05	332	92	7	32786267
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	EPRS1 MYBBP1A SMC1A NUMA1 PINX1 PC PSPC1 GCN1 RAD50	3.15e-05	601	92	9	33658012
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	PPP1R2 CEP162 SMC1A PSMB1 NUMA1 PC	3.15e-05	226	92	6	31452512
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	EPRS1 SMC1A NUMA1 ZNF638 MTREX SMC2 RAD50	3.45e-05	340	92	7	24332808
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	PPP1R2 PMS2 DST GPATCH11 ASPM SMC2 PSPC1 RAD50	3.73e-05	472	92	8	38943005
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PPP1R2 EPRS1 MYBBP1A OTUD5 SMC1A NUMA1 ZNF638 TRRAP ATF2 RAD50	3.92e-05	774	92	10	15302935
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	EPRS1 SMC1A SMC2 PC GCN1 RAD50	4.11e-05	237	92	6	29564676
Pubmed	Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics.	SMC1A SMC2	4.14e-05	4	92	2	9789013
Pubmed	CDK targets Sae2 to control DNA-end resection and homologous recombination.	BRCA1 RAD50	4.14e-05	4	92	2	18716619
Pubmed	TRIM14 inhibits OPTN-mediated autophagic degradation of KDM4D to epigenetically regulate inflammation.	KDM4D KDM4E	4.14e-05	4	92	2	35145029
Pubmed	Expression, cellular distribution and protein binding of the glioma amplified sequence (GAS41), a highly conserved putative transcription factor.	CEP162 NUMA1	4.14e-05	4	92	2	11521196
Pubmed	Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene.	BRCA1 RAD50	4.14e-05	4	92	2	19383352
Pubmed	Histone demethylase KDM4D cooperates with NFIB and MLL1 complex to regulate adipogenic differentiation of C3H10T1/2 mesenchymal stem cells.	KDM4D KDM4E	4.14e-05	4	92	2	32080306
Pubmed	Isolation and characterization of rat skeletal muscle and cytoplasmic actin genes.	KDM4D KDM4E	4.14e-05	4	92	2	6953429
Pubmed	Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response.	BRCA1 RAD50	4.14e-05	4	92	2	10426999
Pubmed	Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway.	BRCA1 SMC1A	4.14e-05	4	92	2	15175241
Pubmed	And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance.	BRCA1 RAD50	4.14e-05	4	92	2	27940552
Pubmed	Loss of CNGB1 protein leads to olfactory dysfunction and subciliary cyclic nucleotide-gated channel trapping.	CNGA2 CNGA4	4.14e-05	4	92	2	16980309
Pubmed	The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells.	PMS2 BRCA1	4.14e-05	4	92	2	17581638
Pubmed	BRCA1 localization to the telomere and its loss from the telomere in response to DNA damage.	BRCA1 RAD50	4.14e-05	4	92	2	19797051
Pubmed	Triapine disrupts CtIP-mediated homologous recombination repair and sensitizes ovarian cancer cells to PARP and topoisomerase inhibitors.	BRCA1 RAD50	4.14e-05	4	92	2	24413181
Pubmed	Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking.	ERC2 RIMS2	4.14e-05	4	92	2	27537483
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	EPRS1 MYBBP1A BRCA1 SMC1A GPATCH1 NUMA1 ZNF638 PINX1 PC PSPC1 NOSIP	4.44e-05	954	92	11	36373674
Pubmed	Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes.	RLF PRDM10 ZNF518B LRIF1	4.58e-05	74	92	4	29795351
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	BRCA1 GPATCH1 DHX38 NUMA1 PC GCN1 LRIF1	4.70e-05	357	92	7	37059091
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	EPRS1 DST NUMA1 ZNF638 PC TXLNG GOLGA3	4.95e-05	360	92	7	33111431
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	MYBBP1A MAGOH PSMB1 ERC2 POTEJ MTREX GOLGA3 DEUP1	5.28e-05	496	92	8	31343991
Pubmed	LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.	MYBBP1A SMC1A SMC2 GCN1	5.92e-05	79	92	4	26446488
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYBBP1A DST DHX38 NUMA1 ZNF638 MTREX TRRAP GCN1 RAD50	5.97e-05	653	92	9	22586326
Pubmed	Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.	MAGOH GPATCH1 DHX38 MTREX	6.22e-05	80	92	4	11991638
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	NUSAP1 EPRS1 MYBBP1A NUMA1 GPATCH11 GOLGA8B PINX1 POTEJ MTREX PC PSPC1 GCN1 NOSIP	6.48e-05	1371	92	13	36244648
Pubmed	Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.	MYBBP1A SMC1A NUMA1 PSPC1 RAD50	6.69e-05	159	92	5	22751105
Interaction	CEP63 interactions	SYNE3 DST MNS1 IFT74 FAM161A SSX2IP SPATA24 TXLNG DEUP1	1.18e-07	179	91	9	int:CEP63
Interaction	NDC80 interactions	IFT74 CEP162 SMC1A SSX2IP SPATA24 ASPM PSPC1 TXLNG GOLGA3 RAD50	1.45e-06	312	91	10	int:NDC80
Interaction	H2BC4 interactions	FSIP2 EPRS1 MAGOH IFT74 NUMA1 ZNF638 ERC2 MTREX NEB	2.60e-06	259	91	9	int:H2BC4
Interaction	LGR4 interactions	EPRS1 MYBBP1A ABCB10 GPATCH1 NUMA1 ZNF638 POTEJ GCN1 GOLGA3	2.86e-06	262	91	9	int:LGR4
Interaction	OFD1 interactions	SYNE3 IFT74 CEP162 GPATCH1 SSX2IP PRKAR2B TRRAP TXLNG DEUP1 RAD50	3.76e-06	347	91	10	int:OFD1
Interaction	SNCA interactions	HBS1L MYBBP1A DST IFT74 PSMB1 LRRK2 NUMA1 PRKAR2B MTREX SMC2 PSPC1 GCN1 NOSIP RAD50	3.82e-06	716	91	14	int:SNCA
Interaction	KDM1A interactions	RLF DST BRCA1 MNS1 NKX2-1 IFT74 FAM161A CEP162 SSX2IP SPATA24 PC PSPC1 TRRAP GCN1 GOLGA3 RAD50	4.35e-06	941	91	16	int:KDM1A
Interaction	CEP128 interactions	SYNE3 IFT74 CEP162 GPATCH1 SSX2IP SPATA24 TXLNG DEUP1 RAD50	7.91e-06	297	91	9	int:CEP128
Interaction	CEP72 interactions	SYNE3 BRCA1 FAM161A CEP162 SPATA24 PRKAR2B	8.99e-06	107	91	6	int:CEP72
Interaction	FBF1 interactions	SYNE3 IFT74 CEP162 GPATCH1 SSX2IP TXLNG DEUP1	1.25e-05	171	91	7	int:FBF1
Interaction	MEN1 interactions	EPRS1 MYBBP1A PMS2 MAGOH SMC1A GPATCH1 DHX38 ESRP1 NUMA1 ZNF638 GREB1 MTREX SMC2 PSPC1 TRRAP ATF2	1.34e-05	1029	91	16	int:MEN1
Interaction	H2BC21 interactions	RLF EPRS1 KDM4D BRCA1 IFT74 NUMA1 ZNF638 ZNF518B NEB SMC2 ATF2 LRIF1 RAD50	1.43e-05	696	91	13	int:H2BC21
Interaction	SMARCA5 interactions	MYBBP1A BRCA1 NKX2-1 SMC1A DHX38 LRRK2 NUMA1 FBXO32 SMC2 GOLGA3	1.79e-05	415	91	10	int:SMARCA5
Interaction	WWTR1 interactions	HBS1L MTRF1 MYBBP1A NKX2-1 IFT74 NUMA1 SMC2 TRRAP GCN1 RAD50	2.07e-05	422	91	10	int:WWTR1
Interaction	LCA5 interactions	IFT74 FAM161A CEP162 GPATCH1 SSX2IP SPATA24	2.19e-05	125	91	6	int:LCA5
Interaction	CEP43 interactions	ARFGEF3 SYNE3 BRCA1 GPATCH1 SSX2IP FBXO32 RAD50	2.46e-05	190	91	7	int:CEP43
Interaction	CDC5L interactions	MYBBP1A MAGOH DST BRCA1 SMC1A GPATCH1 DHX38 TTC14 ZNF638 PSTPIP2 MTREX SMC2 GCN1 RAD50	2.82e-05	855	91	14	int:CDC5L
Interaction	H3-3A interactions	RLF NUSAP1 EPRS1 BRCA1 NKX2-1 SMC1A LRRK2 NUMA1 GPATCH11 PINX1 TRRAP LRIF1 RAD50	3.08e-05	749	91	13	int:H3-3A
Interaction	HECTD1 interactions	NUSAP1 EPRS1 HBS1L MYBBP1A SMC1A GPATCH1 NUMA1 ASPM PINX1 ERC2 MTREX SMC2 TRRAP GCN1 TXLNG	3.24e-05	984	91	15	int:HECTD1
Interaction	RPA4 interactions	ARFGEF3 HBS1L DST BRCA1 IFT74 GPATCH1 NUMA1 ZNF638 PSPC1 TRRAP	3.70e-05	452	91	10	int:RPA4
Interaction	NDN interactions	EPRS1 MYBBP1A SMC1A GPATCH1 SSX2IP NUMA1 FSD2 POTEJ PC GCN1	3.77e-05	453	91	10	int:NDN
Interaction	SSX2IP interactions	BRCA1 IFT74 FAM161A CEP162 GPATCH1 SSX2IP NUMA1 TXLNG	4.81e-05	288	91	8	int:SSX2IP
Interaction	H3C1 interactions	RLF NUSAP1 EPRS1 MYBBP1A SMC1A DHX38 LRRK2 NUMA1 ZNF638 PINX1 NEB TRRAP LRIF1 RAD50	4.98e-05	901	91	14	int:H3C1
Interaction	H2BC8 interactions	PPP1R2 RLF NUSAP1 PMS2 BRCA1 DHX38 NUMA1 PINX1 TRRAP LRIF1 NOSIP	5.65e-05	576	91	11	int:H2BC8
Interaction	SUMO2 interactions	EPRS1 DST BRCA1 SMC1A LRRK2 NUMA1 ZNF638 SMC2 GCN1 RNF43 RAD50	7.11e-05	591	91	11	int:SUMO2
Interaction	EFTUD2 interactions	EPRS1 HBS1L MYBBP1A MAGOH BRCA1 SMC1A GPATCH1 DHX38 NUMA1 ZNF638 MTREX SMC2 PC PSPC1 GCN1 TXLNG NOSIP RAD50	7.22e-05	1449	91	18	int:EFTUD2
Interaction	CSPP1 interactions	SYNE3 CEP162 SSX2IP ASPM DEUP1	7.43e-05	96	91	5	int:CSPP1
Interaction	RCOR1 interactions	RLF DST NKX2-1 IFT74 NUMA1 SMC2 PC GCN1 GOLGA3 RAD50	7.78e-05	494	91	10	int:RCOR1
Interaction	H3C3 interactions	RLF NUSAP1 FSIP2 BRCA1 NKX2-1 SMC1A NUMA1 PINX1 TRRAP LRIF1	7.91e-05	495	91	10	int:H3C3
Interaction	ODF2 interactions	EPRS1 BRCA1 IFT74 GPATCH1 SSX2IP SPATA24	8.13e-05	158	91	6	int:ODF2
Interaction	NACA interactions	BRCA1 LRRK2 FBXO32 PC TRRAP ATF2 LRIF1	9.20e-05	234	91	7	int:NACA
Interaction	TXLNA interactions	EPRS1 DST BRCA1 IFT74 CEP162 TXLNG DEUP1	9.70e-05	236	91	7	int:TXLNA
Interaction	CASP4 interactions	SMC1A PSMB1 SMC2 GCN1	1.04e-04	54	91	4	int:CASP4
Interaction	H2BC12 interactions	EPRS1 DST IFT74 NUMA1 ZNF638 ERC2 MTREX NEB	1.05e-04	322	91	8	int:H2BC12
Interaction	CEP162 interactions	IFT74 CEP162 GPATCH1 SSX2IP SPATA24 TXLNG	1.14e-04	168	91	6	int:CEP162
Interaction	CEBPA interactions	RLF NUSAP1 EPRS1 BRCA1 SMC1A PSMB1 MTREX SMC2 PSPC1 TRRAP ATF2 TXLNG MNDA LRIF1 NOSIP RAD50	1.31e-04	1245	91	16	int:CEBPA
Interaction	SNRNP40 interactions	PRDM10 MAGOH BRCA1 GPATCH1 DHX38 LRRK2 NUMA1 TTC14 PINX1 MTREX NOSIP	1.38e-04	637	91	11	int:SNRNP40
Interaction	STIP1 interactions	EPRS1 MYBBP1A BRCA1 SMC1A PSMB1 LRRK2 MTREX DYRK4 NEB SMC2 GCN1 ATF2 RNF43 RAD50	1.60e-04	1006	91	14	int:STIP1
Interaction	ZNF280D interactions	RLF BRCA1 LRIF1	1.68e-04	24	91	3	int:ZNF280D
Interaction	MATR3 interactions	EPRS1 MYBBP1A MAGOH BRCA1 SMC1A NUMA1 ZNF638 MTREX SMC2 RNF43 RAD50	1.76e-04	655	91	11	int:MATR3
Interaction	BMI1 interactions	ARFGEF3 MYBBP1A MAGOH DST ESRP1 NUMA1 ZNF638 MTREX PSPC1 GCN1 LRIF1	1.85e-04	659	91	11	int:BMI1
Interaction	TPM1 interactions	BRCA1 PSMB1 LRRK2 FBXO32 NEB ATF2 GOLGA3	1.89e-04	263	91	7	int:TPM1
Interaction	SCARNA22 interactions	MYBBP1A SMC1A NUMA1 PSPC1 RAD50	1.97e-04	118	91	5	int:SCARNA22
Interaction	OBSL1 interactions	MYBBP1A DST SMC1A PSMB1 NUMA1 ZNF638 ERC2 MTREX PSPC1 TRRAP GCN1 GOLGA3 RAD50	2.00e-04	902	91	13	int:OBSL1
Interaction	MDH2 interactions	IVD MTRF1 BRCA1 LRRK2 FBXO32 NEB ABCD2 PC TRRAP ATF2	2.13e-04	559	91	10	int:MDH2
Interaction	CEBPB interactions	EPRS1 HBS1L MAGOH BRCA1 NKX2-1 SMC1A PSMB1 NUMA1 ASPM ZNF638 MTREX SMC2 PSPC1 ATF2 TXLNG NOSIP RAD50	2.24e-04	1443	91	17	int:CEBPB
Interaction	CEP135 interactions	IFT74 CEP162 GPATCH1 SSX2IP SPATA24 TXLNG RNF43	2.33e-04	272	91	7	int:CEP135
Interaction	USP7 interactions	PPP1R2 ANKRD31 MYBBP1A DST BRCA1 LRRK2 NUMA1 ASPM ZNF638 ADGRL1 MTREX NEB PC TRRAP ANKH RAD50	2.41e-04	1313	91	16	int:USP7
Interaction	YWHAZ interactions	IVD FSIP2 DST ANKRD34B BRCA1 CEP162 SMC1A SSX2IP LRRK2 ZNF638 PRKAR2B FBXO32 MTREX NEB SMC2 GOLGA3	2.53e-04	1319	91	16	int:YWHAZ
Interaction	SLX4 interactions	BRCA1 SMC1A GPATCH1 DHX38 NUMA1 ZNF518B PC GCN1 LRIF1 RAD50	2.56e-04	572	91	10	int:SLX4
Interaction	RCL1 interactions	NUSAP1 BRCA1 PINX1 PSPC1 TRRAP	2.67e-04	126	91	5	int:RCL1
Interaction	PML interactions	PPP1R2 HBS1L MYBBP1A PMS2 BRCA1 DHX38 NUMA1 ERC2 PC GCN1 ATF2 NOSIP RAD50	2.78e-04	933	91	13	int:PML
Interaction	CEP131 interactions	SYNE3 CEP162 SSX2IP PRKAR2B FBXO32 DEUP1	2.93e-04	200	91	6	int:CEP131
Interaction	NPM1 interactions	FAM184B EPRS1 MYBBP1A PMS2 PRDM10 BRCA1 NUMA1 ASPM ZNF638 NEB PC TRRAP MNDA GOLGA3 RAD50	2.97e-04	1201	91	15	int:NPM1
Interaction	DOCK4 interactions	MAGOH SYNE3 DST BRCA1	3.00e-04	71	91	4	int:DOCK4
Interaction	ADAR interactions	SMC1A NUMA1 ZNF638 POTEJ SMC2 PSPC1 GCN1	3.15e-04	286	91	7	int:ADAR
Interaction	ILF2 interactions	EPRS1 MYBBP1A MAGOH BRCA1 NKX2-1 PC PSPC1 TRRAP GCN1 RAD50	3.28e-04	590	91	10	int:ILF2
Interaction	HAPSTR1 interactions	RPP38-DT EPRS1 HBS1L MYBBP1A NKX2-1 ERC2 POTEJ SMC2 GCN1 ANKH GOLGA3 RAD50	3.45e-04	829	91	12	int:HAPSTR1
Interaction	DDX42 interactions	NUSAP1 EPRS1 BRCA1 PSPC1 LRIF1 NOSIP	3.62e-04	208	91	6	int:DDX42
Interaction	ADARB1 interactions	MYBBP1A SMC1A NUMA1 ZNF638 POTEJ SMC2 PSPC1 GCN1 RAD50	3.65e-04	489	91	9	int:ADARB1
Interaction	MIB1 interactions	SYNE3 IFT74 CEP162 SSX2IP PRKAR2B MTREX GCN1	3.80e-04	295	91	7	int:MIB1
Interaction	RNF126 interactions	EPRS1 SMC1A MTREX RNF43 RAD50	4.06e-04	138	91	5	int:RNF126
Interaction	CUL7 interactions	EPRS1 MYBBP1A MAGOH SMC1A PSMB1 NUMA1 ZNF638 MTREX PSPC1 GCN1 GOLGA3 RAD50	4.10e-04	845	91	12	int:CUL7
Interaction	HDAC1 interactions	RLF MYBBP1A DST BRCA1 NKX2-1 IFT74 SMC1A ZNF638 PRKAR2B SMC2 PC GCN1 GOLGA3 RAD50	4.30e-04	1108	91	14	int:HDAC1
Interaction	LARP7 interactions	EPRS1 MYBBP1A PRDM10 BRCA1 SMC1A DHX38 PSMB1 LRRK2 PINX1 POTEJ SMC2 PC PSPC1 MNDA	4.50e-04	1113	91	14	int:LARP7
Interaction	C9orf78 interactions	HBS1L PRDM10 ABCB10 IFT74 SMC1A NUMA1 PRKAR2B MTREX SMC2 RAD50	4.84e-04	620	91	10	int:C9orf78
Interaction	PPP1CC interactions	PPP1R2 KDM4D MYBBP1A BRCA1 NUMA1 ZNF638 MTREX DYRK4 PSPC1 TRRAP MNDA	4.86e-04	738	91	11	int:PPP1CC
Interaction	PLK1 interactions	SYNE3 BRCA1 CEP162 SMC1A PSMB1 LRRK2 ASPM TP53I3 TRRAP	4.94e-04	510	91	9	int:PLK1
Interaction	EP300 interactions	HBS1L MYBBP1A MAGOH BRCA1 SMC1A DHX38 NUMA1 PINX1 MTREX SMC2 PSPC1 GCN1 ATF2 TXLNG NOSIP RAD50	4.95e-04	1401	91	16	int:EP300
Interaction	NUP107 interactions	SYNE3 BRCA1 NKX2-1 NUMA1 FBXO32 RNF43	4.99e-04	221	91	6	int:NUP107
Interaction	RNF2 interactions	ARFGEF3 EPRS1 MYBBP1A MAGOH SMC1A ESRP1 NUMA1 SPATA24 ZNF638 TRRAP GCN1 RAD50	5.11e-04	866	91	12	int:RNF2
Interaction	ARL4D interactions	EPRS1 MYBBP1A GPATCH1 ZNF638 PC	5.25e-04	146	91	5	int:ARL4D
Interaction	SIRT6 interactions	HBS1L MYBBP1A SMC1A GPATCH1 DHX38 NUMA1 MTREX SMC2 TRRAP RAD50	5.34e-04	628	91	10	int:SIRT6
Interaction	ARRDC4 interactions	ARFGEF3 IFIH1 SMC2 GCN1	5.44e-04	83	91	4	int:ARRDC4
Interaction	SLC2A7 interactions	DHX38 TRRAP	5.55e-04	8	91	2	int:SLC2A7
Interaction	DBF4B interactions	BRCA1 LRRK2 TRRAP	5.71e-04	36	91	3	int:DBF4B
Interaction	RFC4 interactions	EPRS1 BRCA1 NKX2-1 PSPC1 TRRAP RAD50	5.74e-04	227	91	6	int:RFC4
Interaction	NEUROG3 interactions	MYBBP1A DST ASPM ZNF638 GCN1	5.76e-04	149	91	5	int:NEUROG3
Interaction	HNRNPA2B1 interactions	EPRS1 MAGOH BRCA1 SMC1A PSMB1 NUMA1 FBXO32 MTREX SMC2 PSPC1 RNF43	5.81e-04	754	91	11	int:HNRNPA2B1
Interaction	YWHAB interactions	DST CEP162 PSMB1 SSX2IP LRRK2 ZNF638 FBXO32 MTREX NEB TRRAP ATF2 RNF43 RAD50	6.13e-04	1014	91	13	int:YWHAB
Interaction	TRIM29 interactions	PMS2 BRCA1 SMC1A MTREX SMC2 RAD50	6.29e-04	231	91	6	int:TRIM29
Interaction	RFC1 interactions	BRCA1 NKX2-1 SMC1A SMC2 PSPC1 RAD50	6.29e-04	231	91	6	int:RFC1
Interaction	LRRFIP1 interactions	EPRS1 BRCA1 IFT74 NUMA1 SMC2	6.50e-04	153	91	5	int:LRRFIP1
Interaction	CBX3 interactions	RLF PRDM10 BRCA1 DHX38 LRRK2 NUMA1 PINX1 ZNF518B LRIF1 NOSIP	6.65e-04	646	91	10	int:CBX3
Interaction	MKI67 interactions	DST BRCA1 SMC1A NUMA1 ASPM FSD2 SMC2 TRRAP MNDA RNF43	6.81e-04	648	91	10	int:MKI67
Interaction	BICD2 interactions	PPP1R2 HBS1L SYNE3 FAM161A GPATCH1 LRRK2 FBXO32 TXLNG	6.87e-04	426	91	8	int:BICD2
Interaction	FMR1 interactions	EPRS1 MAGOH SSX2IP NUMA1 FSD2 PSPC1 TRRAP NOSIP RAD50	7.05e-04	536	91	9	int:FMR1
Interaction	AKAP4 interactions	FSIP2 PRKAR2B	7.11e-04	9	91	2	int:AKAP4
Interaction	CDC34 interactions	EPRS1 SMC1A FBXO32 SMC2 PC GCN1 RAD50	7.14e-04	328	91	7	int:CDC34
Interaction	KIAA0753 interactions	SYNE3 MNS1 FAM161A CEP162 SSX2IP	7.30e-04	157	91	5	int:KIAA0753
Interaction	PALB2 interactions	MTRF1 SYNE3 BRCA1 GREB1	7.39e-04	90	91	4	int:PALB2
Cytoband	11q21	KDM4D KDM4E DEUP1	9.72e-05	44	92	3	11q21
Cytoband	Ensembl 112 genes in cytogenetic band chr11q21	KDM4D KDM4E DEUP1	2.83e-04	63	92	3	chr11q21
GeneFamily	G-patch domain containing\|Minor histocompatibility antigens	GPATCH1 GPATCH11 PINX1	4.62e-05	22	58	3	579
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	BRCA1 RAD50	1.01e-04	5	58	2	1336
GeneFamily	Structural maintenance of chromosomes proteins\|Cohesin complex	SMC1A SMC2	2.10e-04	7	58	2	761
GeneFamily	Cyclic nucleotide gated channels	CNGA2 CNGA4	4.48e-04	10	58	2	250
GeneFamily	X-linked mental retardation\|RNA helicases	IFIH1 MTREX	5.46e-04	11	58	2	1168
GeneFamily	Rho GTPase activating proteins\|F-BAR domain containing	SRGAP2C PSTPIP2	2.45e-03	23	58	2	1288
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM4D KDM4E	2.67e-03	24	58	2	485
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	MSANTD1 ZNF541	1.25e-02	53	58	2	532
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	RLF NUSAP1 IFIH1 EPRS1 BRCA1 MNS1 IFT74 ASPM ZNF638 MTREX SMC2 RAD50	2.84e-06	656	91	12	M18979
Coexpression	GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_UP	NUSAP1 BRCA1 MNS1 ASPM SMC2 PSPC1 DEUP1	6.38e-06	200	91	7	M5041
Coexpression	WILCOX_RESPONSE_TO_PROGESTERONE_UP	NUSAP1 HBS1L IFT74 CEP162 ASPM SMC2	1.59e-05	153	91	6	M18058
Coexpression	BROWNE_HCMV_INFECTION_48HR_UP	MAGOH BRCA1 DHX38 GREB1 PC MNDA	3.97e-05	180	91	6	M19929
Coexpression	GSE21927_SPLEEN_VS_4T1_TUMOR_MONOCYTE_BALBC_DN	MYBBP1A ABCB10 NKX2-1 SSX2IP PINX1 PC	6.55e-05	197	91	6	M7560
Coexpression	GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_DN	HBS1L BRCA1 NKX2-1 CEP162 ABCD2 SLCO1B1	6.74e-05	198	91	6	M3401
Coexpression	GSE40685_TREG_VS_FOXP3_KO_TREG_PRECURSOR_DN	IFIH1 GIMAP4 WWC3 LRRK2 IFI44L PSTPIP2	6.93e-05	199	91	6	M9308
Coexpression	GSE14308_INDUCED_VS_NATURAL_TREG_DN	RLF TTC14 FSD2 FBXO32 LRIF1 GOLGA3	7.12e-05	200	91	6	M3399
Coexpression	GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_DN	EPRS1 MAGOH PSMB1 ADGRL1 SMC2 ANKH	7.12e-05	200	91	6	M5128
Coexpression	GSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_DN	RLF GIMAP4 ABCB10 SSX2IP FBXO32 MTREX	7.12e-05	200	91	6	M9049
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	ARFGEF3 FSIP2 MGAT5 AFF2 LRRK2 TTC14 GOLGA8B PRKAR2B ADGRL1 ERC2 NEB RIMS2 GOLGA3	1.13e-04	1106	91	13	M39071
Coexpression	EPPERT_PROGENITOR	HBS1L SMC1A SSX2IP PRKAR2B MTREX	1.22e-04	138	91	5	M19232
Coexpression	BIDUS_METASTASIS_UP	NUSAP1 HBS1L MNS1 IFT74 SMC1A ATF2	1.23e-04	221	91	6	M15866
CoexpressionAtlas	facebase_RNAseq_e10.5_MandArch_2500_K1	NUSAP1 MAGOH AFF2 BRCA1 MNS1 IFT74 SMC1A PSMB1 SPATA24 ASPM PINX1 ALAS2 ZNF518B GREB1 MTREX SMC2 PSPC1 LRIF1 RAD50	6.05e-07	1241	88	19	facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlas	facebase_RNAseq_e10.5_MandArch_2500	NUSAP1 IFIH1 MAGOH AFF2 BRCA1 MNS1 IFT74 SMC1A PSMB1 SPATA24 ASPM PINX1 ALAS2 ZNF518B GREB1 MTREX SMC2 PSPC1 LRIF1 RAD50	1.79e-06	1468	88	20	facebase_RNAseq_e10.5_MandArch_2500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	RLF EPRS1 BRCA1 MNS1 DHX38 TTC14 ASPM ZNF638 PINX1 ZNF518B SMC2 TXLNG	1.97e-06	532	88	12	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	NUSAP1 EPRS1 BRCA1 MNS1 IFT74 CEP162 SMC1A NUMA1 GPATCH11 ASPM ERC2 ATF2 GOLGA3 RAD50	7.73e-06	831	88	14	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	RLF NUSAP1 DST MNS1 SMC1A DHX38 ASPM ZNF638 PINX1 SMC2	2.43e-05	469	88	10	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	NUSAP1 SYNE3 BRCA1 MNS1 IFT74 CEP162 SMC1A SSX2IP ASPM GREB1 SMC2 PSPC1 LRIF1 DEUP1 RAD50	2.79e-05	1060	88	15	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	NUSAP1 BRCA1 MNS1 IFT74 CEP162 SMC1A ASPM RAD50	4.50e-05	311	88	8	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500_K1	NUSAP1 EPRS1 MYBBP1A MAGOH BRCA1 MNS1 IFT74 ASPM PINX1 GREB1 MTREX SMC2 PSPC1 LRIF1 RAD50	8.10e-05	1164	88	15	facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500_K1
CoexpressionAtlas	MESO-15 amniotic fluid MSC_vs_MESO-15 blastocyst-Confounder_removed-fold2.0_adjp0.05	FAM184B EPRS1 MYBBP1A BRCA1 IFT74 FAM161A SMC1A SSX2IP TTC14 SPATA24 ASPM GOLGA8B PRKAR2B ADGRL1 GREB1 SMC2 PSPC1	1.05e-04	1479	88	17	PCBC_ratio_MESO-15 amniotic fluid MSC_vs_MESO-15 blastocyst_cfr-2X-p05
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500	NUSAP1 SYNE3 AFF2 BRCA1 MNS1 IFT74 CEP162 SMC1A SSX2IP ASPM GREB1 SMC2 PSPC1 LRIF1 DEUP1 RAD50	2.07e-04	1414	88	16	facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	NUSAP1 EPRS1 BRCA1 MNS1 NKX2-1 IFT74 CEP162 SMC1A ASPM ERC2 RIMS2 LRIF1 RAD50	2.10e-04	989	88	13	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	NUSAP1 BRCA1 MNS1 SMC1A ASPM ERC2 RIMS2	2.40e-04	298	88	7	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K4
CoexpressionAtlas	B cells, proB.CLP.BM, CD19- IgM- CD43+ CD24- AA4.1+ CD45R- CD117+ IL7R+, Bone marrow, avg-1	MGAT5 BRCA1 LRRK2 ASPM PRKAR2B PSTPIP2 SMC2 ABCD2	2.78e-04	405	88	8	GSM538343_500
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	NUSAP1 AFF2 BRCA1 MNS1 IFT74 SMC1A TTC14 ASPM PINX1 ZNF518B MTREX SMC2 PSPC1 LRIF1 DEUP1 RAD50	2.95e-04	1459	88	16	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	PP_RBC_top-relative-expression-ranked_2500_k-means-cluster#1	OTUD5 SSX2IP ASPM PRKAR2B PSTPIP2 LRIF1 PARP15	3.17e-04	312	88	7	PP_RBC_2500_K1
CoexpressionAtlas	kidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_1000	MYBBP1A PMS2 BRCA1 MNS1 ASPM ZNF518B GREB1	3.43e-04	316	88	7	gudmap_kidney_P3_CapMes_Crym_k4_1000
CoexpressionAtlas	gamma delta T cells, Tgd.vg2-24ahi.Th, TCRd+ Vg2- CD24+, Thymus, avg-2	NUSAP1 GIMAP4 MGAT5 BRCA1 MNS1 ASPM ADGRL1 SMC2	3.66e-04	422	88	8	GSM476658_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	BRCA1 MNS1 IFT74 CEP162 SMC1A NUMA1 GPATCH11 SMC2 ATF2 ZNF583 GOLGA3	3.73e-04	780	88	11	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlas	facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500	NUSAP1 EPRS1 MYBBP1A MAGOH BRCA1 MNS1 IFT74 ASPM PINX1 GREB1 MTREX SMC2 PSPC1 LRIF1 RAD50	3.98e-04	1347	88	15	facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#5	NUSAP1 BRCA1 MNS1 ASPM ERC2 RIMS2	4.10e-04	232	88	6	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K5
CoexpressionAtlas	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4	NUSAP1 AFF2 BRCA1 MNS1 OTUD5 IFT74 CEP162 SMC1A ASPM ZNF518B SMC2 PSPC1 ZNF583 DEUP1 RAD50	4.75e-04	1370	88	15	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlas	facebase_RNAseq_e8.5_FloorPlate_2500_K3	NUSAP1 MYBBP1A MAGOH BRCA1 MNS1 IFT74 GPATCH1 PINX1 ZNF518B GREB1 MTREX SMC2 PSPC1 LRIF1 RAD50	4.79e-04	1371	88	15	facebase_RNAseq_e8.5_FloorPlate_2500_K3
ToppCell	Transverse-(2)_B_cell-(24)_B_cell_cycling\|Transverse / shred on region, Cell_type, and subtype	MTRF1 AFF2 BRCA1 ABCB10 MNS1 LRRK2 ASPM SMC2	8.96e-09	200	92	8	e3f9736227151f23f0e331eec0a7a15ce464b517
ToppCell	Transverse-B_cell-B_cell_cycling\|Transverse / Region, Cell class and subclass	MTRF1 AFF2 BRCA1 ABCB10 MNS1 LRRK2 ASPM SMC2	8.96e-09	200	92	8	0e270f8019d9f22068ca426d661937262a5cd331
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mast-Mast-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NUSAP1 ABCB10 SSX2IP ASPM PRKAR2B ALAS2 SMC2	9.97e-08	181	92	7	c35ca98c474e31917e0a53c092397e0d8d18b37c
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NUSAP1 BRCA1 MNS1 ASPM PRKAR2B SMC2	1.55e-06	172	92	6	6fcc16f1067672967ecbcdfdc727649ae9891dd9
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IFIH1 MTRF1 SRGAP2C DST OTUD5 RNF43	1.72e-06	175	92	6	334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 IFT74 SPATA24 ASPM SMC2 PSPC1	2.16e-06	182	92	6	39f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 LRRIQ3 MNS1 ASPM PRKAR2B SMC2	2.30e-06	184	92	6	16aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IFIH1 SRGAP2C LRRK2 IFI44L PSTPIP2 MNDA	2.37e-06	185	92	6	f30fb9d75cdb757b206312992aaf7485bc900f96
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 ABCB10 MNS1 SSX2IP PRKAR2B ALAS2	2.52e-06	187	92	6	dceca7ae3dae96078cccc17a0d8a61b06fa6dffb
ToppCell	droplet-Marrow-nan-3m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRCA1 ABCB10 SSX2IP ASPM PRKAR2B ANKH	2.68e-06	189	92	6	8a38baee58a27c2fa3f4bd131ab9f15723ed9295
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 ABCB10 MNS1 ASPM ALAS2 SMC2	2.76e-06	190	92	6	4288189e3a499c395896c950598810b02f401685
ToppCell	droplet-Marrow-BM-30m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 ABCB10 MNS1 ASPM ALAS2 SMC2	2.85e-06	191	92	6	08be56a4055a73c920d345fd3b2052a5ccb675d8
ToppCell	droplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l12-14\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NUSAP1 ARFGEF3 BRCA1 SMC1A ASPM SMC2	2.94e-06	192	92	6	52d0aa51e3b6ab3608a5f40bdde9f8134b3afd94
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GIMAP4 GOLGA8B IFI44L FBXO32 ABCD2 NOSIP	3.03e-06	193	92	6	2901d7a9672a8cf70c9f1c752685b45e4d79ac70
ToppCell	Severe_COVID-19-Myeloid-proliferating_Myeloid_cells\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	NUSAP1 DST BRCA1 MNS1 ASPM SMC2	3.03e-06	193	92	6	0d85025690c9cd545cba30abc38acbdd6a39b153
ToppCell	COVID-19_Severe-Lymphoid_T/NK-CD4+_T_activated\|COVID-19_Severe / Disease group, lineage and cell class	GIMAP4 GOLGA8B IFI44L FBXO32 ABCD2 NOSIP	3.03e-06	193	92	6	beb862d38b88572836b0a797c8efef7a2492e0b9
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GIMAP4 GOLGA8B IFI44L FBXO32 ABCD2 NOSIP	3.03e-06	193	92	6	f4310faa13fc8ce99a217e2d1c9cc733683797a1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GIMAP4 GOLGA8B IFI44L FBXO32 ABCD2 NOSIP	3.03e-06	193	92	6	f8af695457d2a0a911a5ac491742465864ebda37
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GIMAP4 GOLGA8B IFI44L FBXO32 ABCD2 NOSIP	3.03e-06	193	92	6	089aece40130034a89a5213be778f10b0787eeba
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NUSAP1 DST BRCA1 MNS1 ASPM SMC2	3.12e-06	194	92	6	cb39850e9577015b6b9834e98c36b412bae7d462
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NUSAP1 DST BRCA1 MNS1 ASPM SMC2	3.12e-06	194	92	6	408597c9aa302a44b112c1d612c21fbb0227a82a
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NUSAP1 DST BRCA1 MNS1 ASPM SMC2	3.12e-06	194	92	6	193cc20fefbd795a4ad59e401a95af47d30603e7
ToppCell	BAL-Severe-Myeloid-Myeloid\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NUSAP1 DST BRCA1 MNS1 ASPM SMC2	3.12e-06	194	92	6	2360b5f995b360419de41612368cab9fb61781a1
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	NUSAP1 DST BRCA1 MNS1 ASPM SMC2	3.12e-06	194	92	6	903ae11708b0cb24538c6982abd57fe6fa95b8d3
ToppCell	BAL-Severe-Myeloid-Myeloid\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	NUSAP1 DST BRCA1 MNS1 ASPM SMC2	3.12e-06	194	92	6	58406502a8cbcc3037f79a1b6a683df408297ae5
ToppCell	erythropoietic-Polychromatic_Erythroblast\|World / Lineage and Cell class	NUSAP1 ABCB10 ASPM PRKAR2B ALAS2 SMC2	3.40e-06	197	92	6	604fcbf47f073c2af344e1b16b615a78ef838dc9
ToppCell	(11)_FOXN4+\|World / shred by cell type by condition	NUSAP1 BRCA1 MNS1 CEP162 ASPM DEUP1	3.51e-06	198	92	6	516b1acdf997dd8debc3dca066519366e507b414
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_1\|356C / Donor, Lineage, Cell class and subclass (all cells)	NUSAP1 BRCA1 ASPM SMC2 MNDA ANKH	3.51e-06	198	92	6	f801157468e59b5d049f703feadc9bb0f11e85cc
ToppCell	Transverse-B_cell-B_cell_cycling\|B_cell / Region, Cell class and subclass	AFF2 BRCA1 ABCB10 LRRK2 ASPM SMC2	3.61e-06	199	92	6	170ae68963d31f3b821b6f0e8f0c039bea0bc981
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	NUSAP1 BRCA1 PINX1 GREB1 SMC2 TRRAP	3.71e-06	200	92	6	691b3edf7d8449556e8bf611662eb85772959f0f
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells-Stem_cells\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	NUSAP1 BRCA1 PINX1 GREB1 SMC2 TRRAP	3.71e-06	200	92	6	36a110aa91a791fdf1142e7869e8aa0d342402d0
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2\|World / Primary Cells by Cluster	NUSAP1 BRCA1 MNS1 SMC1A ASPM SMC2	3.71e-06	200	92	6	4923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NUSAP1 BRCA1 MNS1 SMC1A ASPM SMC2	3.71e-06	200	92	6	43571c9284d4e41402a2d1eefc1efe2ce8476d4a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells-Neuroepithelial_cell\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	NUSAP1 BRCA1 PINX1 GREB1 SMC2 TRRAP	3.71e-06	200	92	6	4e077aa7faddcebdfc54667f8b3990704441005b
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2-5\|World / Primary Cells by Cluster	NUSAP1 BRCA1 MNS1 SMC1A ASPM SMC2	3.71e-06	200	92	6	dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCell	mild-CD8+_T_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANKRD31 GOLGA8B IFI44L FBXO32 ABCD2 NOSIP	3.71e-06	200	92	6	c825320599a61a4c629d736f5c0fd6f1f405540a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	NUSAP1 BRCA1 PINX1 GREB1 SMC2 TRRAP	3.71e-06	200	92	6	d17ba4239e1fd702a3d757687110f0f2c6f91ef7
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Severe / Disease, condition lineage and cell class	GIMAP4 GOLGA8B IFI44L FBXO32 ABCD2 NOSIP	3.71e-06	200	92	6	deeed668b129e66156b5f6abe1a07a9bf842a14d
ToppCell	Healthy-CD4+_T_activated\|Healthy / disease group, cell group and cell class	IFIH1 IFT74 IFI44L ABCD2 PC	1.27e-05	145	92	5	45e8089fdf7d6f69b383816d8945e39fba24c873
ToppCell	IIH-CD4-antiviral_CD4\|IIH / Condition, Cell_class and T cell subcluster	IFIH1 GIMAP4 AFF2 IFI44L NOSIP	1.41e-05	148	92	5	ec626a44cea83f2a0e5c27fc8182f96446d297ac
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARFGEF3 PINX1 ERC2 POTEJ RIMS2	1.99e-05	159	92	5	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	facs-Lung-nan-3m-Epithelial-type_I_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARFGEF3 NKX2-1 ESRP1 ERC2 RNF43	2.44e-05	166	92	5	11b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCell	LV-11._Adipocyte\|World / Chamber and Cluster_Paper	LRRIQ3 SYNE3 PRKAR2B ABCD2 PC	2.44e-05	166	92	5	7e5852891714465c6228c9f955fd511ec79d0e02
ToppCell	facs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARFGEF3 NKX2-1 ESRP1 ERC2 RNF43	2.44e-05	166	92	5	fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCell	10x5'-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|Lung / Manually curated celltypes from each tissue	NUSAP1 MNS1 ASPM GREB1 SMC2	2.51e-05	167	92	5	82739226347d74897be000f429b73543a031af96
ToppCell	10x5'-Lung-Hematopoietic_progenitors\|Lung / Manually curated celltypes from each tissue	NUSAP1 MNS1 ASPM GREB1 SMC2	2.51e-05	167	92	5	dec18caf0475002d4ad3c7bc7fc3050cbc8e6bae
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NUSAP1 PRDM10 SYNE3 ASPM SMC2	2.59e-05	168	92	5	52fd65024af8683db11d931f7563cbe8eb815d1c
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-lymphocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 MNS1 PRKAR2B ALAS2 SMC2	2.82e-05	171	92	5	ff117bf1a0755aa7d7c3db29749a7b9b90cc0b2f
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-CD45\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 MNS1 PRKAR2B ALAS2 SMC2	2.90e-05	172	92	5	95219814e37259e34be053572cc95d4639360c27
ToppCell	droplet-Lung-nan-21m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSANTD1 MTRF1 LRRIQ3 ASPM ANKH	2.98e-05	173	92	5	2eb6e9fc3a3654f6f86fbd112e80a18814afd103
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	IFIH1 MTRF1 SRGAP2C DST OTUD5	3.14e-05	175	92	5	da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NUSAP1 PRDM10 SYNE3 PSTPIP2 MNDA	3.23e-05	176	92	5	90f8bb11f339f67f08692a0c33dd420f5cda2861
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NUSAP1 NKX2-1 ESRP1 ASPM SMC2	3.32e-05	177	92	5	a68c3688f12aee22f3cb4049c4bccacbacb0fae6
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|343B / Donor, Lineage, Cell class and subclass (all cells)	NUSAP1 FAM184B MTRF1 PINX1 ADGRL1	3.41e-05	178	92	5	5289ac61637224ae70ffbc2d164d73116f10af40
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NUSAP1 BRCA1 MNS1 SMC2 MNDA	3.50e-05	179	92	5	e1bfd553c043ebc070ccf8545d489ba16d9b2ef4
ToppCell	LPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARFGEF3 NKX2-1 LRRK2 ESRP1 RNF43	3.69e-05	181	92	5	0513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NUSAP1 MNS1 ESRP1 ASPM SMC2	3.79e-05	182	92	5	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	LPS_only-Epithelial_alveolar-AT_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARFGEF3 NKX2-1 LRRK2 ESRP1 RNF43	3.89e-05	183	92	5	e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCell	wk_15-18-Hematologic-Meg-ery-Cycling_definitive_erythroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NUSAP1 ABCB10 SSX2IP ASPM ALAS2	3.99e-05	184	92	5	238eba615b4e04967d44ac7858a6673bdd7f67e9
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NUSAP1 BRCA1 SMC1A ASPM SMC2	3.99e-05	184	92	5	8260e688ec42a1374727bc85dceb7edd19a8b662
ToppCell	droplet-Lung-nan-21m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARFGEF3 NKX2-1 ESRP1 PC CNGA2	4.10e-05	185	92	5	6938ac3cab536cf8a474eba441ce6dcdfcc43b53
ToppCell	droplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NUSAP1 BRCA1 ASPM PRKAR2B SMC2	4.10e-05	185	92	5	57c1eb50a4456d20953e48d5dc3b0ea3d0d81b6d
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NUSAP1 MNS1 SPATA24 ASPM SMC2	4.10e-05	185	92	5	0e0f043ad6d2a62cd47ce39911ad81feab4a4d7e
ToppCell	droplet-Lung-nan-21m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARFGEF3 NKX2-1 ESRP1 PC CNGA2	4.10e-05	185	92	5	0e7351cd6d6e6e8c29573042e168da50ee496cfc
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NUSAP1 MNS1 SPATA24 ASPM SMC2	4.10e-05	185	92	5	89b85ce8026dc80c1bd9f76dfe16401c173b7946
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	NUSAP1 AFF2 BRCA1 ASPM SMC2	4.10e-05	185	92	5	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NUSAP1 LRRIQ3 MNS1 PRKAR2B SMC2	4.10e-05	185	92	5	b4af9ae4c358b48357cb135b740266e1652d886a
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	NUSAP1 DST BRCA1 ASPM SMC2	4.10e-05	185	92	5	9d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCell	facs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 BRCA1 MNS1 ASPM SMC2	4.21e-05	186	92	5	9feef5936985e936b3d88f9d1bb012abb6468570
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|bone_marrow / Manually curated celltypes from each tissue	NUSAP1 BRCA1 ASPM SMC2 MNDA	4.21e-05	186	92	5	e82d5e7a976b9cfa2b4640c7a7cd1cfea19c4806
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 MNS1 SSX2IP PRKAR2B ALAS2	4.21e-05	186	92	5	ac6e32cf07f0f013101ca7aedae0c562857f182b
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 MNS1 SSX2IP PRKAR2B ALAS2	4.21e-05	186	92	5	7cdcf507a9a1349ed2cf62b79116367c3fc732dd
ToppCell	facs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 BRCA1 MNS1 ASPM SMC2	4.21e-05	186	92	5	89f5b06bc56674af304912d481ac697c7c870904
ToppCell	droplet-Marrow-nan-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 ABCB10 MNS1 ALAS2 SMC2	4.31e-05	187	92	5	99724aa3dbdcb073ea3bfe80cc825ecae5495db8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NUSAP1 BRCA1 MNS1 ASPM SMC2	4.31e-05	187	92	5	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	droplet-Spleen-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRCA1 MNS1 SSX2IP ASPM PRKAR2B	4.42e-05	188	92	5	1a3f95b4fd7611c634666761ddf21f1e58e56af8
ToppCell	droplet-Marrow-BM-30m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB10 MNS1 SSX2IP PRKAR2B ALAS2	4.42e-05	188	92	5	f1a9d8ea174a4bef0fae8188e3bd96b7ac1a39bb
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	NUSAP1 BRCA1 ASPM ALAS2 SMC2	4.42e-05	188	92	5	f5102e8d95506c25c675094b86162a6a50087b64
ToppCell	facs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 BRCA1 MNS1 ASPM SMC2	4.54e-05	189	92	5	bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB10 MNS1 SMC1A ALAS2 SMC2	4.54e-05	189	92	5	16dfc37d8d390ed7f927bc844c47c9c5a89a0928
ToppCell	facs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 BRCA1 MNS1 ASPM SMC2	4.54e-05	189	92	5	96f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB10 MNS1 SMC1A ALAS2 SMC2	4.54e-05	189	92	5	3ade3fa9369e85304b20d7233b581f18ad5ecc89
ToppCell	droplet-Marrow-nan-24m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB10 MNS1 SSX2IP PRKAR2B ALAS2	4.54e-05	189	92	5	98ace332c3c046694c6ade47de8c8bf57ec51271
ToppCell	Int-URO-Lymphocyte-T_NK-T_NK_proliferative\|Int-URO / Disease, Lineage and Cell Type	NUSAP1 BRCA1 MNS1 ASPM SMC2	4.65e-05	190	92	5	005967c540418b85311308072a07c684f4296aef
ToppCell	droplet-Spleen-nan-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 ABCB10 MNS1 PRKAR2B ALAS2	4.65e-05	190	92	5	a273fc119baebc11020009c923beafeebb6428c9
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NUSAP1 BRCA1 ASPM SMC2 ZNF541	4.65e-05	190	92	5	c3c65d1f24e0ebdbb9adb617bed299a668f423f5
ToppCell	Dividing_Macrophages-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	NUSAP1 BRCA1 MNS1 ASPM SMC2	4.77e-05	191	92	5	3e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUSAP1 BRCA1 MNS1 ASPM SMC2	4.77e-05	191	92	5	c8b99bd3a30c81ee4deba9cbf0196920ab3ab550
ToppCell	droplet-Marrow-BM-1m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB10 MNS1 SSX2IP PRKAR2B ANKH	4.77e-05	191	92	5	d78d4fbb0b8317dbf14e32182466a432abef3e93
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST PRKAR2B ERC2 PC ANKH	4.77e-05	191	92	5	f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NUSAP1 BRCA1 MNS1 ASPM SMC2	4.77e-05	191	92	5	50854384fdaa0efa2e3227659d544ed09ac102f2
ToppCell	wk_20-22-Hematologic-Myeloid-Cycling_DC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NUSAP1 BRCA1 ASPM SMC2 MNDA	4.77e-05	191	92	5	1da569ebcfab4e1a95315430ae77a17a1f119263
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic-lymphocyte-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NUSAP1 BRCA1 MNS1 ASPM SMC2	4.77e-05	191	92	5	56b45259dfc38bd5ea43b0e3adf47e7e2c043a5d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARFGEF3 MGAT5 TTC14 NEB RNF43	4.89e-05	192	92	5	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	NS-critical-d_07-13-Myeloid-Monocyte-derived_Macrophage\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IFIH1 GIMAP4 IFI44L PSTPIP2 MNDA	5.01e-05	193	92	5	0dd83b21e164147abfd511a927615c40a28781a2
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARFGEF3 NKX2-1 LRRK2 ESRP1 GOLGA8B	5.01e-05	193	92	5	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	(3)_Chondrocytes-(33)_Chondro-prol/rest\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	NUSAP1 MNS1 SPATA24 ASPM SMC2	5.14e-05	194	92	5	4a207630d72059345b10010f5cfd3b1462458324
ToppCell	3'_v3-Lung-Myeloid_Mac-Cycling_Myeloid-Mac\|Lung / Manually curated celltypes from each tissue	NUSAP1 BRCA1 MNS1 ASPM SMC2	5.14e-05	194	92	5	a8ae49157ca3f9e8b3f1750a995aee012dc859b6
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|367C / Donor, Lineage, Cell class and subclass (all cells)	NUSAP1 BRCA1 ASPM SMC2 MNDA	5.14e-05	194	92	5	a12b64945e10f00aa983678a02586c59badc1570
ToppCell	critical-Myeloid-Monocyte-derived_Macrophage\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	IFIH1 GIMAP4 IFI44L PSTPIP2 MNDA	5.14e-05	194	92	5	e36d1fd141bdcbd9ed66a33de6cdfde77189a0c1
Computational	Neighborhood of SMC2L1	NUSAP1 ASPM SMC2	4.68e-04	33	50	3	GNF2_SMC2L1
Computational	Neighborhood of TTK	NUSAP1 ASPM SMC2	7.69e-04	39	50	3	GNF2_TTK
Computational	Neighborhood of RRM2	NUSAP1 SMC1A ASPM	8.29e-04	40	50	3	GNF2_RRM2
Computational	Neighborhood of CENPE	NUSAP1 ASPM SMC2	8.91e-04	41	50	3	GNF2_CENPE
Computational	Neighborhood of PPP2R5B	AFF2 BRCA1 ABCB10 CEP162 ATF2	1.20e-03	173	50	5	MORF_PPP2R5B
Computational	Neighborhood of HMMR	NUSAP1 ASPM SMC2	1.33e-03	47	50	3	GNF2_HMMR
Computational	Genes upregulated in subsets of cells of a given type within various tumors	NUSAP1 ASPM SMC2	1.50e-03	49	50	3	GAVISH_3CA_METAPROGRAM_CD4_T_CELLS_CELL_CYCLE
Computational	Genes upregulated in subsets of cells of a given type within various tumors	NUSAP1 ASPM SMC2	1.50e-03	49	50	3	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CELL_CYCLE
Computational	Genes upregulated in subsets of cells of a given type within various tumors	EPRS1 DST NEB	1.50e-03	49	50	3	GAVISH_3CA_MALIGNANT_METAPROGRAM_41_UNASSIGNED
Computational	Genes upregulated in subsets of cells of a given type within various tumors	NUSAP1 ASPM SMC2	1.50e-03	49	50	3	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CELL_CYCLE
Computational	Genes upregulated in subsets of cells of a given type within various tumors	NUSAP1 ASPM SMC2	1.59e-03	50	50	3	GAVISH_3CA_METAPROGRAM_EPITHELIAL_CELL_CYCLE
Computational	Genes upregulated in subsets of cells of a given type within various tumors	NUSAP1 ASPM SMC2	1.59e-03	50	50	3	GAVISH_3CA_METAPROGRAM_ENDOTHELIAL_CELL_CYCLE
Computational	Neighborhood of CKS2	NUSAP1 ASPM SMC2	1.59e-03	50	50	3	GNF2_CKS2
Computational	Genes upregulated in subsets of cells of a given type within various tumors	DST SMC1A ZNF638	1.59e-03	50	50	3	GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Computational	Neighborhood of NOS2A	AFF2 BRCA1 ABCB10 CEP162 NEB ATF2	2.07e-03	288	50	6	MORF_NOS2A
Computational	Neighborhood of CDC20	NUSAP1 ASPM SMC2	2.21e-03	56	50	3	GNF2_CDC20
Computational	Neighborhood of CCNB2	NUSAP1 ASPM SMC2	2.32e-03	57	50	3	GNF2_CCNB2
Disease	Neoplasm of uncertain or unknown behavior of ovary	PMS2 BRCA1 RNF43	8.85e-05	29	88	3	C0496920
Disease	Ovarian Carcinoma	PMS2 BRCA1 RNF43	9.82e-05	30	88	3	C0029925
Disease	Breast Cancer, Familial	PMS2 BRCA1 RAD50	9.82e-05	30	88	3	C0346153
Disease	Benign tumor of pancreas	BRCA1 RNF43	6.71e-04	13	88	2	C0347284
Disease	Hereditary Breast and Ovarian Cancer Syndrome	BRCA1 RAD50	7.82e-04	14	88	2	C0677776
Disease	Pancreatic carcinoma	BRCA1 RNF43	1.45e-03	19	88	2	C0235974
Disease	aspartate aminotransferase measurement	ANKRD31 HBS1L MGAT5 BRCA1 WWC3 ZNF638 PINX1 ERC2 GCN1	1.50e-03	904	88	9	EFO_0004736
Disease	Ovarian Serous Adenocarcinoma	LRRK2 TRRAP	2.14e-03	23	88	2	C1335177
Disease	stomach carcinoma (is_marker_for)	BRCA1 RNF43	2.33e-03	24	88	2	DOID:5517 (is_marker_for)
Disease	breast cancer (implicated_via_orthology)	BRCA1 RAD50	2.52e-03	25	88	2	DOID:1612 (implicated_via_orthology)
Disease	open-angle glaucoma	MGAT5 DST FBXO32 ANKH	2.60e-03	191	88	4	EFO_0004190

Protein segments in the cluster

Peptide	Gene	Start	Entry
GHKVEMKQLQKSYKA	ABCD2	311	Q9UBJ2
HDMKRKEREYNKLKE	SSX2IP	196	Q9Y2D8
RESAGKNYNKMHKRE	ADGRL1	596	O94910
KNYNKMHKRERTCKD	ADGRL1	601	O94910
NADYYMQEAKKLKHK	AFF2	1071	P51816
DKMEKQQYKSEVHKA	C14orf28	111	Q4W4Y0
KYASKVDHVMQLARK	ABCB10	376	Q9NRK6
MKFKLHVNSARQYKD	ATF2	1	P15336
DMKYKAVRTENTHLK	DEUP1	416	Q05D60
AHVRKHQQRQKYKKM	ASPM	1591	Q8IZT6
ATAEAQHIIYKMKEK	ETNPPL	381	Q8TBG4
QKCHKKNMKDRYVEV	ESRP1	506	Q6NXG1
NHRYKMKRQAKDKAA	NKX2-1	211	P43699
KTMDAKKNYEQKCRD	PSTPIP2	136	Q9H939
QEAHKYMEANKNIGK	TP53I3	311	Q53FA7
DIKEKVKNIHGYMKD	RAD50	946	Q92878
NINKRTMHKYEQESK	HBS1L	286	Q9Y450
TMHKYEQESKKAGKA	HBS1L	291	Q9Y450
HQKKEIARQMKAYEK	NOSIP	76	Q9Y314
VDHQSVSKAKMVKYL	ANKRD34B	56	A5PLL1
KHYNFKENLTNKKEM	ANKRD31	926	Q8N7Z5
KQTKRNAKVYEKMAS	MSANTD1	66	Q6ZTZ1
SYQVKKRQMDIKNDH	PARP15	536	Q460N3
HFQYQAIMKEKRLKE	LEXM	106	Q3ZCV2
KKMDHIKKRKTENAY	LRIF1	636	Q5T3J3
KKEHMTKQRVEQYVL	GREB1	726	Q4ZG55
QHLNKDKDMLKYKVT	MGAT5	666	Q09328
EKLQKNMKELKVHYE	DST	3891	Q03001
LYSKMLAKVKQVHKE	IFI44L	331	Q53G44
KNDVMIRKEAYVHKS	MAGOH	41	P61326
YMKQQYEEDLRKIKH	FAM184B	401	Q9ULE4
KQDLLEKKMAYHLQK	FSIP2	291	Q5CZC0
EKQKRYDEFLVHMKQ	GPATCH1	511	Q9BRR8
KSKISKNRVHYMKFT	PINX1	116	Q96BK5
FTQYHKKKKAMTVGE	KDM4D	86	Q6B0I6
GVFTQYHKKKKAMRV	KDM4E	81	B2RXH2
NKESKHKMSYSGRVK	LRRK2	2401	Q5S007
SIKKANMKRENKAYS	GCN1	786	Q92616
QIEVYKSHSKFMKTK	ERC2	421	O15083
KQYSSKTKMVQHIRK	PRDM10	841	Q9NQV6
MESIDQYIERKKKHF	NUSAP1	196	Q9BXS6
VVSMKLKAEKKGNHY	IVD	176	P26440
TSAQKEMKTKHKAYE	GOLGA3	986	Q08378
DKIMEKKQDHTYRVF	ALAS2	151	P22557
KKRQFEMKRKLHYNE	PPP1R2	136	P41236
QEKYDLHQVKKAMLR	MYBBP1A	116	Q9BQG0
KLHQQFEMYKEQVKK	RIMS2	91	Q9UQ26
KKKKYNQMPVRHSRN	BRCA1	651	P38398
RKKDKDNTYNVVHMK	DYRK4	156	Q9NR20
QKYKELKKREEHMDT	IFT74	356	Q96LB3
AEEKLESYRKKIHMK	GPATCH11	146	Q8N954
ESYRKKIHMKNQAEE	GPATCH11	151	Q8N954
MTEYKKRKQQHNLSA	ARFGEF3	2026	Q5TH69
MKTKRNIAKHYKNNP	IFIH1	886	Q9BYX4
VYRKQKKKMENESAT	ANKH	451	Q9HCJ1
KMKKERDQAKDQIAY	CEP162	821	Q5TB80
IVKNNAKKRKMYESF	PRKAR2B	256	P31323
IQKMAYHKDNKELSV	FCRL2	46	Q96LA5
NTEKKKLNTDLYHMK	GOLGA8B	131	A8MQT2
AKLEKMYQDKLHLKE	FAM161A	111	Q3B820
NYDVAAKKRKKDMLN	FBXO32	56	Q969P5
IEARLKMYKHSNNKA	PSMB1	96	P20618
QEYLDSMKKNKVHRD	OTUD5	551	Q96G74
KLQMEKAKTHYDAKK	NUMA1	1611	Q14980
MLQKKSVHKKNTIYE	MNDA	326	P41218
KKLKAAYMNKERAAQ	MNS1	126	Q8NEH6
FKQYVNKNSKHEELM	EPRS1	641	P07814
RMKAEYDAVKAKAQK	SYNE3	196	Q6ZMZ3
KKQMEKKLAEQEAHY	GIMAP4	276	Q9NUV9
SAKDEIHKNMYKLEK	FSD2	211	A1L4K1
DTMKHQSQLRKKKYL	POTEJ	626	P0CG39
KLMEFVYKNQKAHVR	RNF43	171	Q68DV7
MKEKHQAKYTENKLK	SRGAP2C	231	P0DJJ0
KHKALQKYMENLSKE	MTRF1	71	O75570
AMKKKYQEKDINASE	SLCO1B1	646	Q9Y6L6
QAKIDAVKHYMQFRK	CNGA2	386	Q16280
VKKYMKLQHVNRKLE	CNGA4	286	Q8IV77
ENQDKREKEYGVKHM	RPP38-DT	11	Q8N326
KKVIQKVEAFEHRMY	MTREX	791	P42285
ENAKHYLDMKNRREK	RLF	701	Q13129
EKLMQKTQQYHKERE	PSPC1	246	Q8WXF1
ESYMAQVLDQKHKKA	SPATA24	176	Q86W54
NAQKHYKKRKGDMDE	SMC1A	321	Q14683
HKYMQKSLELREKQA	TTC14	426	Q96N46
KVDYRTEQKFADHMK	DHX38	496	Q92620
KNKQAEVKKMDSGYR	SMC2	431	O95347
NIKKEYAKMVQVLHA	PMS2	176	P54278
KEATESRHKYEQMKQ	TXLNG	331	Q9NUQ3
KFKEVKKAYVEANQM	PC	886	P11498
SNRKMLKESQKLHYV	TRRAP	901	Q9Y4A5
RHKQNTEKFMAKQRK	ZNF638	1951	Q14966
HEPQKKSYRKKSVEM	ZNF583	186	Q96ND8
KSVEMKHRKVYVEKK	ZNF583	196	Q96ND8
YRHEQAAEKMLKKAS	WWC3	1036	Q9ULE0
KKDFYLIHKMIQTKT	ZNF541	1181	Q9H0D2
MKLKKVHKNNYQVVD	ZNF518B	1011	Q9C0D4
KKQEYHKEKVRVVAM	LRRIQ3	431	A6PVS8
MHVAKIQSDREYKKD	NEB	2821	P20929