Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	tyrosine-ester sulfotransferase activity	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.15e-11	4	55	4	GO:0017067
GeneOntologyMolecularFunction	amine sulfotransferase activity	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.15e-11	4	55	4	GO:0047685
GeneOntologyMolecularFunction	flavonol 3-sulfotransferase activity	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.57e-10	5	55	4	GO:0047894
GeneOntologyMolecularFunction	steroid sulfotransferase activity	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.79e-09	7	55	4	GO:0050294
GeneOntologyMolecularFunction	sulfate binding	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.42e-09	9	55	4	GO:0043199
GeneOntologyMolecularFunction	aryl sulfotransferase activity	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.07e-08	10	55	4	GO:0004062
GeneOntologyMolecularFunction	3'-phosphoadenosine 5'-phosphosulfate binding	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.62e-08	13	55	4	GO:0050656
GeneOntologyMolecularFunction	sulfotransferase activity	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.58e-05	55	55	4	GO:0008146
GeneOntologyMolecularFunction	transferase activity, transferring sulphur-containing groups	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.14e-05	74	55	4	GO:0016782
GeneOntologyMolecularFunction	glycosyltransferase activity	MFNG ART1 DPY19L1 GBE1 WDFY3	1.16e-03	288	55	5	GO:0016757
GeneOntologyMolecularFunction	cargo receptor activity	TMED10 CUBN SORL1	1.66e-03	85	55	3	GO:0038024
GeneOntologyMolecularFunction	sulfur compound binding	SULT1A2 SULT1A4 SULT1A1 SULT1A3 FST	1.93e-03	323	55	5	GO:1901681
GeneOntologyMolecularFunction	hexosyltransferase activity	MFNG DPY19L1 GBE1 WDFY3	2.71e-03	211	55	4	GO:0016758
GeneOntologyBiologicalProcess	4-nitrophenol metabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.26e-10	5	55	4	GO:0018960
GeneOntologyBiologicalProcess	purine ribonucleoside bisphosphate metabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.05e-07	17	55	4	GO:0034035
GeneOntologyBiologicalProcess	3'-phosphoadenosine 5'-phosphosulfate metabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.05e-07	17	55	4	GO:0050427
GeneOntologyBiologicalProcess	ethanol catabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.05e-07	17	55	4	GO:0006068
GeneOntologyBiologicalProcess	ethanol metabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.35e-07	18	55	4	GO:0006067
GeneOntologyBiologicalProcess	primary alcohol catabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.86e-07	23	55	4	GO:0034310
GeneOntologyBiologicalProcess	sulfation	SULT1A2 SULT1A4 SULT1A1 SULT1A3	7.59e-07	27	55	4	GO:0051923
GeneOntologyBiologicalProcess	flavonoid metabolic process	SULT1A4 SULT1A1 SULT1A3	5.03e-06	13	55	3	GO:0009812
GeneOntologyBiologicalProcess	alcohol catabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	7.41e-06	47	55	4	GO:0046164
GeneOntologyBiologicalProcess	primary alcohol metabolic process	SULT1A2 SULT1A4 DHRS3 SULT1A1 SULT1A3	9.24e-06	106	55	5	GO:0034308
GeneOntologyBiologicalProcess	estrogen metabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.11e-05	52	55	4	GO:0008210
GeneOntologyBiologicalProcess	organic hydroxy compound catabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	4.30e-05	73	55	4	GO:1901616
GeneOntologyBiologicalProcess	catechol-containing compound metabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	4.53e-05	74	55	4	GO:0009712
GeneOntologyBiologicalProcess	catecholamine metabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	4.53e-05	74	55	4	GO:0006584
GeneOntologyBiologicalProcess	biogenic amine metabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.05e-04	121	55	4	GO:0006576
GeneOntologyBiologicalProcess	dopamine catabolic process	SULT1A4 SULT1A3	3.10e-04	10	55	2	GO:0042420
GeneOntologyBiologicalProcess	catecholamine catabolic process	SULT1A4 SULT1A3	3.78e-04	11	55	2	GO:0042424
GeneOntologyBiologicalProcess	catechol-containing compound catabolic process	SULT1A4 SULT1A3	3.78e-04	11	55	2	GO:0019614
GeneOntologyBiologicalProcess	regulation of BMP signaling pathway	HOXA13 ELAPOR2 FST SORL1	4.12e-04	131	55	4	GO:0030510
GeneOntologyBiologicalProcess	xenobiotic metabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.45e-04	141	55	4	GO:0006805
GeneOntologyBiologicalProcess	purine nucleoside bisphosphate metabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.59e-04	142	55	4	GO:0034032
GeneOntologyBiologicalProcess	phenol-containing compound metabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.59e-04	142	55	4	GO:0018958
GeneOntologyBiologicalProcess	nucleoside bisphosphate metabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.59e-04	142	55	4	GO:0033865
GeneOntologyBiologicalProcess	ribonucleoside bisphosphate metabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.59e-04	142	55	4	GO:0033875
GeneOntologyBiologicalProcess	phenol-containing compound catabolic process	SULT1A4 SULT1A3	6.22e-04	14	55	2	GO:0019336
GeneOntologyBiologicalProcess	amine metabolic process	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.53e-04	148	55	4	GO:0009308
GeneOntologyBiologicalProcess	alcohol metabolic process	SULT1A2 SULT1A4 DHRS3 SULT1A1 SULT1A3 CUBN	7.77e-04	412	55	6	GO:0006066
GeneOntologyBiologicalProcess	small molecule catabolic process	SULT1A2 SULT1A4 DHDH SULT1A1 SULT1A3 CUBN	8.69e-04	421	55	6	GO:0044282
GeneOntologyBiologicalProcess	response to glucocorticoid	SULT1A2 SULT1A4 SULT1A1 SULT1A3	8.74e-04	160	55	4	GO:0051384
GeneOntologyBiologicalProcess	hormone metabolic process	SULT1A2 SULT1A4 DHRS3 SULT1A1 SULT1A3	9.77e-04	286	55	5	GO:0042445
GeneOntologyCellularComponent	Cul3-RING ubiquitin ligase complex	ENC1 KLHL12 KEAP1	1.47e-04	39	55	3	GO:0031463
MousePheno	enlarged gallbladder	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.81e-06	28	45	4	MP:0009342
MousePheno	abnormal gallbladder size	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.15e-06	32	45	4	MP:0020134
MousePheno	abnormal gallbladder morphology	SULT1A2 SULT1A4 SULT1A1 SULT1A3	4.01e-05	60	45	4	MP:0005084
Domain	BTB	GZF1 KLHL28 RHOBTB1 ENC1 KLHL12 KEAP1	2.32e-06	131	55	6	PF00651
Domain	Sulfotransferase_dom	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.70e-06	36	55	4	IPR000863
Domain	Sulfotransfer_1	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.70e-06	36	55	4	PF00685
Domain	BTB	GZF1 KLHL28 RHOBTB1 ENC1 KLHL12 KEAP1	7.37e-06	160	55	6	PS50097
Domain	BTB-kelch_protein	KLHL28 ENC1 KLHL12 KEAP1	7.63e-06	43	55	4	IPR017096
Domain	BTB	GZF1 KLHL28 RHOBTB1 ENC1 KLHL12 KEAP1	1.44e-05	180	55	6	SM00225
Domain	BTB/POZ_dom	GZF1 KLHL28 RHOBTB1 ENC1 KLHL12 KEAP1	1.69e-05	185	55	6	IPR000210
Domain	SKP1/BTB/POZ	GZF1 KLHL28 RHOBTB1 ENC1 KLHL12 KEAP1	1.90e-05	189	55	6	IPR011333
Domain	Kelch	KLHL28 ENC1 KLHL12 KEAP1	2.54e-05	58	55	4	SM00612
Domain	Gal_Oxase/kelch_b-propeller	KLHL28 ENC1 KLHL12 KEAP1	2.72e-05	59	55	4	IPR011043
Domain	BACK	KLHL28 ENC1 KLHL12 KEAP1	2.90e-05	60	55	4	SM00875
Domain	BACK	KLHL28 ENC1 KLHL12 KEAP1	3.10e-05	61	55	4	PF07707
Domain	BACK	KLHL28 ENC1 KLHL12 KEAP1	3.10e-05	61	55	4	IPR011705
Domain	Kelch_1	KLHL28 ENC1 KLHL12 KEAP1	5.34e-05	70	55	4	PF01344
Domain	Kelch_1	KLHL28 ENC1 KLHL12 KEAP1	5.34e-05	70	55	4	IPR006652
Domain	-	KLHL28 KLHL12 KEAP1	6.72e-05	27	55	3	2.130.10.80
Domain	DUSP	USP20 USP33	1.27e-04	6	55	2	SM00695
Domain	DUSP	USP20 USP33	1.27e-04	6	55	2	PF06337
Domain	Gal_Oxidase_b-propeller	KLHL28 KLHL12 KEAP1	1.36e-04	34	55	3	IPR015916
Domain	-	USP20 USP33	1.77e-04	7	55	2	3.30.2230.10
Domain	DUSP	USP20 USP33	1.77e-04	7	55	2	PS51283
Domain	Pept_C19_DUSP	USP20 USP33	1.77e-04	7	55	2	IPR006615
Domain	ZnF_UBP	USP20 USP33	4.60e-04	11	55	2	SM00290
Domain	Kelch-typ_b-propeller	KLHL28 ENC1 KEAP1	5.69e-04	55	55	3	IPR015915
Domain	Znf_UBP	USP20 USP33	7.57e-04	14	55	2	IPR001607
Domain	zf-UBP	USP20 USP33	7.57e-04	14	55	2	PF02148
Domain	ZF_UBP	USP20 USP33	7.57e-04	14	55	2	PS50271
Domain	-	SULT1A2 RHOBTB1 SULT1A1 TDRD9 RTEL1 PEX6 CHD6 PFKFB3	1.44e-03	746	55	8	3.40.50.300
Domain	P-loop_NTPase	SULT1A2 RHOBTB1 SULT1A1 TDRD9 RTEL1 PEX6 CHD6 PFKFB3	3.20e-03	848	55	8	IPR027417
Domain	DNA/RNA_helicase_DEAH_CS	RTEL1 CHD6	4.76e-03	35	55	2	IPR002464
Domain	EGF_3	TENM4 TLL2 CUBN SORL1	5.04e-03	235	55	4	PS50026
Domain	EGF	TENM4 TLL2 CUBN SORL1	5.04e-03	235	55	4	SM00181
Domain	DEAH_ATP_HELICASE	RTEL1 CHD6	5.59e-03	38	55	2	PS00690
Domain	-	TENM4 SORL1	5.88e-03	39	55	2	2.120.10.30
Domain	EGF-like_dom	TENM4 TLL2 CUBN SORL1	6.18e-03	249	55	4	IPR000742
Pathway	KEGG_MEDICUS_ENV_FACTOR_PHIP_TO_DNA_ADDUCTS	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.74e-10	5	43	4	M47807
Pathway	KEGG_SULFUR_METABOLISM	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.26e-08	13	43	4	M18256
Pathway	WP_RETINOL_METABOLISM	SULT1A2 SULT1A4 DHRS3 SULT1A1 SULT1A3	2.07e-07	44	43	5	MM15851
Pathway	WP_ESTROGEN_METABOLISM	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.27e-07	22	43	4	MM15888
Pathway	REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.37e-07	23	43	4	MM14597
Pathway	REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES	SULT1A2 SULT1A4 SULT1A1 SULT1A3	7.63e-07	24	43	4	M16289
Pathway	REACTOME_PARACETAMOL_ADME	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.71e-06	39	43	4	MM15695
Pathway	WP_SULFATION_BIOTRANSFORMATION_REACTION	SULT1A2 SULT1A4 SULT1A1	1.74e-05	17	43	3	M39483
Pathway	REACTOME_PARACETAMOL_ADME	SULT1A4 SULT1A1 SULT1A3	9.14e-05	29	43	3	M45015
Pathway	WP_ARYLAMINE_METABOLISM	SULT1A2 SULT1A1	1.35e-04	6	43	2	M39437
Pathway	REACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.08e-04	107	43	4	MM14595
Pathway	REACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.31e-04	109	43	4	M18788
Pathway	REACTOME_DRUG_ADME	SULT1A2 SULT1A4 SULT1A1 SULT1A3	4.62e-04	119	43	4	MM15692
Pathway	KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_SEQUESTOSOME_1_LIKE_RECEPTOR	MAP1LC3B2 WDFY3	8.08e-04	14	43	2	M47975
Pathway	WP_METAPATHWAY_BIOTRANSFORMATION	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.18e-03	153	43	4	MM15844
Pubmed	Steroid sulfotransferases.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.03e-12	4	56	4	8943792
Pubmed	Mapping of the phenol sulfotransferase gene (STP) to human chromosome 16p12.1-p11.2 and to mouse chromosome 7.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.03e-12	4	56	4	8288252
Pubmed	A single mutation converts the nucleotide specificity of phenol sulfotransferase from PAP to AMP.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.03e-12	4	56	4	12390022
Pubmed	Formation of hepatic DNA adducts by methyleugenol in mouse models: drastic decrease by Sult1a1 knockout and strong increase by transgenic human SULT1A1/2.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.03e-12	4	56	4	24318996
Pubmed	Molecular cloning of cDNA encoding the phenol/aryl form of sulfotransferase (mSTp1) from mouse liver.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.03e-12	4	56	4	8424956
Pubmed	Bioactivation of food genotoxicants 5-hydroxymethylfurfural and furfuryl alcohol by sulfotransferases from human, mouse and rat: a comparative study.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.03e-12	4	56	4	25370010
Pubmed	Decreased phenol sulfotransferase activities associated with hyperserotonemia in autism spectrum disorders.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.03e-12	4	56	4	33414449
Pubmed	Identification of a new subfamily of sulphotransferases: cloning and characterization of canine SULT1D1.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.01e-11	5	56	4	11389699
Pubmed	Hemoglobin adducts of furfuryl alcohol in genetically modified mouse models: Role of endogenous sulfotransferases 1a1 and 1d1 and transgenic human sulfotransferases 1A1/1A2.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.01e-11	5	56	4	29908303
Pubmed	Determination of sulfotransferase forms involved in the metabolic activation of the genotoxicant 1-hydroxymethylpyrene using bacterially expressed enzymes and genetically modified mouse models.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.01e-11	5	56	4	24802129
Pubmed	The effect of knockout of sulfotransferases 1a1 and 1d1 and of transgenic human sulfotransferases 1A1/1A2 on the formation of DNA adducts from furfuryl alcohol in mouse models.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.01e-11	5	56	4	25053625
Pubmed	Inactivation of Wt1 causes pre-granulosa cell to steroidogenic cell transformation and defect of ovary development†.	SULT1A2 SULT1A4 SULT1A1 SULT1A3 FST	1.80e-10	21	56	5	32301970
Pubmed	The mouse Plk gene: structural characterization, chromosomal localization and identification of a processed Plk pseudogene.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.10e-10	7	56	4	9370299
Pubmed	Chromosomal localization of three vacuolar-H+ -ATPase 16 kDa subunit (ATP6V0C) genes in the murine genome.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.10e-10	7	56	4	12438748
Pubmed	Alternative splicing, gene localization, and binding of SH2-B to the insulin receptor kinase domain.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	4.20e-10	8	56	4	10594240
Pubmed	The gene encoding the heart/muscle isoform of cytochrome c oxidase subunit VIII maps to mouse chromosome 7.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	7.55e-10	9	56	4	9166597
Pubmed	Chromosomal localization of the mouse genes encoding the ERK1 and ERK2 isoforms of MAP kinases.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	7.55e-10	9	56	4	9060415
Pubmed	Msx3: a novel murine homologue of the Drosophila msh homeobox gene restricted to the dorsal embryonic central nervous system.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	7.55e-10	9	56	4	8887328
Pubmed	Structure of the human gene (COX6A2) for the heart/muscle isoform of cytochrome c oxidase subunit VIa and its chromosomal location in humans, mice, and cattle.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	7.55e-10	9	56	4	9177785
Pubmed	Ethanol sulfation by the human cytosolic sulfotransferases: a systematic analysis.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	7.55e-10	9	56	4	23207770
Pubmed	Molecular characterization and mapping of murine genes encoding three members of the stefin family of cysteine proteinase inhibitors.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	7.55e-10	9	56	4	8468045
Pubmed	Inhibitory effects of kynurenic acid, a tryptophan metabolite, and its derivatives on cytosolic sulfotransferases.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	7.55e-10	9	56	4	19548878
Pubmed	Rat phenol-preferring sulfotransferase genes (Stp and Stp2): localization to mouse chromosomes 7 and 17.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.26e-09	10	56	4	7601475
Pubmed	Localization of the murine cholecystokinin A and B receptor genes.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.97e-09	11	56	4	7613026
Pubmed	Sulfotransferases in the bioactivation of xenobiotics.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.97e-09	11	56	4	11154739
Pubmed	Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.97e-09	11	56	4	9034160
Pubmed	Sulfotransferases: genetics and role in toxicology.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.97e-09	11	56	4	10720750
Pubmed	Tbx6, a mouse T-Box gene implicated in paraxial mesoderm formation at gastrulation.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.97e-09	11	56	4	8954725
Pubmed	Identification of four chromosomal loci determining obesity in a multifactorial mouse model.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.95e-09	12	56	4	7706460
Pubmed	Genomic organization and DNA sequences of two human phenol sulfotransferase genes (STP1 and STP2) on the short arm of chromosome 16.	SULT1A2 SULT1A1 SULT1A3	3.95e-09	3	56	3	8912648
Pubmed	Identification of two human brain aryl sulfotransferase cDNAs.	SULT1A4 SULT1A1 SULT1A3	3.95e-09	3	56	3	8363592
Pubmed	A single amino acid, glu146, governs the substrate specificity of a human dopamine sulfotransferase, SULT1A3.	SULT1A4 SULT1A1 SULT1A3	3.95e-09	3	56	3	9855620
Pubmed	PHR1 encodes an abundant, pleckstrin homology domain-containing integral membrane protein in the photoreceptor outer segments.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	4.26e-09	13	56	4	10585447
Pubmed	Structural and chemical profiling of the human cytosolic sulfotransferases.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	4.26e-09	13	56	4	17425406
Pubmed	cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	8.12e-09	15	56	4	1741163
Pubmed	Interaction of the Brain-Selective Sulfotransferase SULT4A1 with Other Cytosolic Sulfotransferases: Effects on Protein Expression and Function.	SULT1A4 SULT1A1 SULT1A3	1.58e-08	4	56	3	32152050
Pubmed	Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.81e-08	18	56	4	20056724
Pubmed	Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects.	SULT1A2 SULT1A1 SULT1A3	4.71e-07	10	56	3	11535246
Pubmed	Update on the Kelch-like (KLHL) gene family.	KLHL28 ENC1 KLHL12 KEAP1	5.84e-07	41	56	4	23676014
Pubmed	Crystal structures of SULT1A2 and SULT1A1 *3: insights into the substrate inhibition and the role of Tyr149 in SULT1A2.	SULT1A2 SULT1A1	2.55e-06	2	56	2	20417180
Pubmed	Active site mutations and substrate inhibition in human sulfotransferase 1A1 and 1A3.	SULT1A1 SULT1A3	2.55e-06	2	56	2	14871892
Pubmed	Association between functional genetic polymorphisms of human sulfotransferases 1A1 and 1A2.	SULT1A2 SULT1A1	2.55e-06	2	56	2	10762004
Pubmed	Human liver thermolabile phenol sulfotransferase: cDNA cloning, expression and characterization.	SULT1A4 SULT1A3	2.55e-06	2	56	2	8117269
Pubmed	Localisation of aryl sulfotransferase expression in human tissues using hybridisation histochemistry and immunohistochemistry.	SULT1A2 SULT1A1	2.55e-06	2	56	2	9566757
Pubmed	Single nucleotide polymorphisms in SULT1A1 and SULT1A2 in a Korean population.	SULT1A2 SULT1A1	2.55e-06	2	56	2	23358261
Pubmed	Functional characterization of two human sulphotransferase cDNAs that encode monoamine- and phenol-sulphating forms of phenol sulphotransferase: substrate kinetics, thermal-stability and inhibitor-sensitivity studies.	SULT1A1 SULT1A3	2.55e-06	2	56	2	8093002
Pubmed	Role of Conformational Dynamics of Sulfotransferases SULT1A1 and SULT1A3 in Substrate Specificity.	SULT1A1 SULT1A3	2.55e-06	2	56	2	38069221
Pubmed	Sulfation pharmacogenetics: SULT1A1 and SULT1A2 allele frequencies in Caucasian, Chinese and African-American subjects.	SULT1A2 SULT1A1	2.55e-06	2	56	2	11207031
Pubmed	Differential roles of human monoamine (M)-form and simple phenol (P)-form phenol sulfotransferases in drug metabolism.	SULT1A1 SULT1A3	2.55e-06	2	56	2	12761191
Pubmed	Genetic polymorphisms of sulfotransferases (SULT1A1 and SULT1A2) in a Turkish population.	SULT1A2 SULT1A1	2.55e-06	2	56	2	20936502
Pubmed	The relationship among the polymorphisms of SULT1A1, 1A2 and different types of cancers in Taiwanese.	SULT1A2 SULT1A1	2.55e-06	2	56	2	12469224
Pubmed	Impact of SULT1A3/SULT1A4 genetic polymorphisms on the sulfation of phenylephrine and salbutamol by human SULT1A3 allozymes.	SULT1A4 SULT1A3	2.55e-06	2	56	2	31145702
Pubmed	Sulfation of "estrogenic" alkylphenols and 17beta-estradiol by human platelet phenol sulfotransferases.	SULT1A2 SULT1A3	2.55e-06	2	56	2	10617600
Pubmed	Deubiquitinase USP33 promotes the glycolysis and growth of osteosarcoma by modifying PFKFB3 ubiquitination and degradation.	PFKFB3 USP33	2.55e-06	2	56	2	37034227
Pubmed	Genetic polymorphisms and linkage disequilibrium of sulfotransferase SULT1A1 and SULT1A2 in a Korean population: comparison of other ethnic groups.	SULT1A2 SULT1A1	2.55e-06	2	56	2	16133548
Pubmed	Crystal structure of human catecholamine sulfotransferase.	SULT1A4 SULT1A3	2.55e-06	2	56	2	10543947
Pubmed	Structural similarity and diversity of sulfotransferases.	SULT1A2 SULT1A1	2.55e-06	2	56	2	8033246
Pubmed	Primary structures and properties of two related forms of aryl sulfotransferases in human liver.	SULT1A2 SULT1A1	2.55e-06	2	56	2	7581483
Pubmed	Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.	USP20 USP33	2.55e-06	2	56	2	33792613
Pubmed	Effects of human SULT1A3/SULT1A4 genetic polymorphisms on the sulfation of acetaminophen and opioid drugs by the cytosolic sulfotransferase SULT1A3.	SULT1A4 SULT1A3	2.55e-06	2	56	2	29705271
Pubmed	Phylogenomic approaches to common problems encountered in the analysis of low copy repeats: the sulfotransferase 1A gene family example.	SULT1A4 SULT1A3	2.55e-06	2	56	2	15752422
Pubmed	Maps from two interspecific backcross DNA panels available as a community genetic mapping resource.	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.72e-06	72	56	4	8075499
Pubmed	Structural basis for dimerization quality control.	KLHL12 KEAP1	7.63e-06	3	56	2	32814905
Pubmed	Human platelet phenolsulfotransferases: cDNA cloning, stable expression in V79 cells and identification of a novel allelic variant of the phenol-sulfating form.	SULT1A1 SULT1A3	7.63e-06	3	56	2	7695643
Pubmed	Sulphation of acetaminophen by the human cytosolic sulfotransferases: a systematic analysis.	SULT1A1 SULT1A3	7.63e-06	3	56	2	26067475
Pubmed	Structure of human estrogen and aryl sulfotransferase gene. Two mRNA species issued from a single gene.	SULT1A4 SULT1A3	7.63e-06	3	56	2	7961757
Pubmed	In silico mechanistic profiling to probe small molecule binding to sulfotransferases.	SULT1A1 SULT1A3	7.63e-06	3	56	2	24039991
Pubmed	Identification of a deubiquitinating enzyme subfamily as substrates of the von Hippel-Lindau tumor suppressor.	USP20 USP33	7.63e-06	3	56	2	12056827
Pubmed	Genotypes of CYP1A1, SULT1A1 and SULT1A2 and risk of squamous cell carcinoma of esophagus: outcome of a case-control study from Kashmir, India.	SULT1A2 SULT1A1	7.63e-06	3	56	2	26455829
Pubmed	Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation.	USP20 USP33	7.63e-06	3	56	2	12865408
Pubmed	Genetic polymorphisms in platelet-related proteins and coronary artery disease: investigation of candidate genes, including N-acetylgalactosaminyltransferase 4 (GALNT4) and sulphotransferase 1A1/2 (SULT1A1/2).	SULT1A2 SULT1A1	7.63e-06	3	56	2	18259693
Pubmed	NRP/B mutations impair Nrf2-dependent NQO1 induction in human primary brain tumors.	ENC1 KEAP1	7.63e-06	3	56	2	18981988
Pubmed	hDKIR, a human homologue of the Drosophila kelch protein, involved in a ring-like structure.	KLHL12 KEAP1	7.63e-06	3	56	2	15383316
Pubmed	Dimerization quality control ensures neuronal development and survival.	ENC1 KLHL12 KEAP1	7.81e-06	24	56	3	30190310
Pubmed	A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.	RHOBTB1 ENC1 MUC19 KLHL12	1.21e-05	87	56	4	37495603
Pubmed	Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling.	USP20 USP33	1.52e-05	4	56	2	21525354
Pubmed	Human phenol sulfotransferase STP2 gene: molecular cloning, structural characterization, and chromosomal localization.	SULT1A2 SULT1A1	1.52e-05	4	56	2	8661000
Pubmed	The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization.	USP20 USP33	1.52e-05	4	56	2	19424180
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	SULT1A2 SULT1A4 KLHL28 SULT1A1 SULT1A3 SRPK1 KLHL12 KEAP1	2.12e-05	730	56	8	34857952
Pubmed	SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair.	RTEL1 KEAP1 SORL1	2.28e-05	34	56	3	31495888
Pubmed	Sulfation of afimoxifene, endoxifen, raloxifene, and fulvestrant by the human cytosolic sulfotransferases (SULTs): A systematic analysis.	SULT1A2 SULT1A1	2.54e-05	5	56	2	26169578
Pubmed	Ectodermal-neural cortex 1 down-regulates Nrf2 at the translational level.	ENC1 KEAP1	3.80e-05	6	56	2	19424503
Pubmed	Human SULT1A3 pharmacogenetics: gene duplication and functional genomic studies.	SULT1A4 SULT1A3	3.80e-05	6	56	2	15358107
Pubmed	USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110.	USP20 USP33	3.80e-05	6	56	2	23486064
Pubmed	MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors.	USP20 USP33	5.32e-05	7	56	2	23166351
Pubmed	Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: role of D1 receptor-N-methyl-D-aspartate receptor coupling.	SULT1A4 SULT1A3	5.32e-05	7	56	2	24136195
Pubmed	Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway.	ENC1 KEAP1	7.09e-05	8	56	2	15983046
Pubmed	A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.	RHOBTB1 USP33	7.09e-05	8	56	2	22157079
Pubmed	FBXL17/spastin axis as a novel therapeutic target of hereditary spastic paraplegia.	KLHL12 USP20	1.39e-04	11	56	2	35869491
Pubmed	USP25 regulates KEAP1-NRF2 anti-oxidation axis and its inactivation protects acetaminophen-induced liver injury in male mice.	KLHL12 KEAP1	1.66e-04	12	56	2	37339955
Pubmed	Common variants at five new loci associated with early-onset inflammatory bowel disease.	SULT1A2 SULT1A1	1.66e-04	12	56	2	19915574
Pubmed	NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress-Induced DPP3-KEAP1 Interaction.	CHD6 KEAP1	1.96e-04	13	56	2	28416489
Pubmed	Understanding the development of oral epithelial organs through single cell transcriptomic analysis.	ENC1 FST CNTN2	2.27e-04	73	56	3	35831953
Pubmed	Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology.	MAP1LC3B2 WDFY3	2.29e-04	14	56	2	25198012
Pubmed	Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes.	SULT1A2 SULT1A1	2.64e-04	15	56	2	18632753
Pubmed	Developmental and sexual dimorphic atlas of the prenatal mouse external genitalia at the single-cell level.	HOXA13 FST	2.64e-04	15	56	2	34155146
Pubmed	Distal Limb Patterning Requires Modulation of cis-Regulatory Activities by HOX13.	HOXA13 TENM4	3.01e-04	16	56	2	27974206
Pubmed	A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer.	SULT1A2 SULT1A1	3.01e-04	16	56	2	12419832
Pubmed	Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia.	HOXA13 TENM4	3.41e-04	17	56	2	15944189
Pubmed	Olfactory receptors and signalling elements in the Grueneberg ganglion.	OR5T2 OR8H1	3.41e-04	17	56	2	16805845
Interaction	SULT1C2 interactions	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.48e-07	19	52	4	int:SULT1C2
Interaction	SULT1A3 interactions	SULT1A2 SULT1A4 SULT1A1 SULT1A3	4.03e-07	24	52	4	int:SULT1A3
Interaction	SULT1A4 interactions	SULT1A4 SULT1A1 SULT1A3	5.78e-06	14	52	3	int:SULT1A4
Interaction	SULT1A2 interactions	SULT1A2 SULT1A1 SULT1A3	1.52e-05	19	52	3	int:SULT1A2
Interaction	SULT1A1 interactions	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.68e-05	67	52	4	int:SULT1A1
Interaction	SULT4A1 interactions	SULT1A2 SULT1A1 SULT1A3	3.16e-05	24	52	3	int:SULT4A1
Interaction	KLHL28 interactions	KLHL28 KLHL12 KEAP1	4.54e-05	27	52	3	int:KLHL28
Interaction	FBXL17 interactions	KLHL28 ENC1 KLHL12 KEAP1	6.84e-05	85	52	4	int:FBXL17
Interaction	KLHL12 interactions	KLHL28 NDC80 KLHL12 KEAP1	1.50e-04	104	52	4	int:KLHL12
Interaction	SULT1B1 interactions	SULT1A4 SULT1A3	1.81e-04	8	52	2	int:SULT1B1
Interaction	SULT1C4 interactions	SULT1A4 SULT1A3 RTEL1 PEX6	1.86e-04	110	52	4	int:SULT1C4
Cytoband	11q12.1	OR6Q1 OR5B17 OR5T2 OR8H1	4.64e-05	161	56	4	11q12.1
Cytoband	Ensembl 112 genes in cytogenetic band chr16p11	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.77e-04	278	56	4	chr16p11
Cytoband	16p12.1	SULT1A2 SULT1A1	4.31e-04	25	56	2	16p12.1
Cytoband	Ensembl 112 genes in cytogenetic band chr11q12	OR6Q1 OR5B17 OR5T2 OR8H1	8.46e-04	345	56	4	chr11q12
GeneFamily	Sulfotransferases, cytosolic	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.00e-08	14	44	4	762
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	GZF1 KLHL28 RHOBTB1 ENC1 KLHL12 KEAP1	8.30e-07	134	44	6	861
GeneFamily	Kelch like\|BTB domain containing	KLHL28 ENC1 KLHL12 KEAP1	3.19e-06	42	44	4	617
Coexpression	VERNOCHET_ADIPOGENESIS	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.54e-07	24	53	4	MM1317
Coexpression	LANDIS_BREAST_CANCER_PROGRESSION_DN	SULT1A2 MFNG SULT1A4 SULT1A1 SULT1A3	4.32e-07	75	53	5	MM1084
Coexpression	LANDIS_ERBB2_BREAST_TUMORS_324_DN	SULT1A2 MFNG SULT1A4 SULT1A1 SULT1A3 GBE1	7.63e-07	157	53	6	MM1099
Coexpression	BREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_DN	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.10e-05	68	53	4	MM770
Coexpression	INGRAM_SHH_TARGETS_UP	SULT1A2 SULT1A4 SULT1A1 SULT1A3 OLFML2B	1.60e-05	156	53	5	MM550
Coexpression	YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_7	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.55e-05	84	53	4	MM873
Coexpression	SOBOLEV_PBMC_PANDEMRIX_AGE_18_64YO_MEDIUM_HIGH_ADVERSE_EVENTS_SCORE_1DY_DN	SULT1A2 SULT1A4	4.00e-05	5	53	2	M41007
Coexpression	LIU_OVARIAN_CANCER_TUMORS_AND_XENOGRAFTS_XDGS_UP	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.83e-05	108	53	4	MM1334
Coexpression	GROSS_HYPOXIA_VIA_HIF1A_DN	GZF1 GBE1 PFKFB3 FST	7.34e-05	110	53	4	M1309
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_UP	SULT1A4 KLHL28 SULT1A1 SULT1A3 WDFY3	8.05e-05	219	53	5	M41199
Coexpression	LE_EGR2_TARGETS_DN	SULT1A2 SULT1A4 SULT1A1 SULT1A3	9.33e-05	117	53	4	MM1139
Coexpression	GROSS_HYPOXIA_VIA_HIF1A_DN	GZF1 GBE1 PFKFB3 FST	1.44e-04	131	53	4	MM1127
Coexpression	IWANAGA_CARCINOGENESIS_BY_KRAS_DN	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.62e-04	135	53	4	MM753
Coexpression	GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN	HMGXB4 ENC1 WDFY3 KEAP1 SOCS6 ST13P5 PLEKHG5 TBL2	1.82e-04	794	53	8	MM982
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-Venous_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MFNG SULT1A4 ART1 SULT1A3 KANK3	2.79e-06	179	55	5	040a7e916baaf81f44339dc721ab2afcd2c22388
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Immature_CPNs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	TENM4 DPY19L1 ENC1 CNTN2 SORL1	4.57e-06	198	55	5	32d58379a89be19b6b1a494bf033416546771c19
ToppCell	severe-Myeloid-Neutrophils_4\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TDRD9 SRPK1 WDFY3 PFKFB3 SORL1	4.68e-06	199	55	5	50242666def13e5d4149c563ae000d6768f086f7
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DHRS3 OLFML2B ENC1 FST	6.90e-05	178	55	4	0fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TENM4 DPY19L1 TLL2 SRPK1	6.90e-05	178	55	4	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	droplet-Fat-Gat-18m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHOBTB1 SULT1A1 KANK3 PLEKHG5	7.05e-05	179	55	4	08cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DHRS3 SULT1A1 ENC1 PLCE1	8.52e-05	188	55	4	842982de2197770f999a70083ed9fca40ac22d79
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DHRS3 SULT1A1 ENC1 PLCE1	8.52e-05	188	55	4	a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
ToppCell	RA-11._Adipocyte\|World / Chamber and Cluster_Paper	TENM4 DHRS3 GBE1 PFKFB3	8.52e-05	188	55	4	4dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Radial_glial-RG\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	DHRS3 KANK3 GBE1 PFKFB3	9.25e-05	192	55	4	ee822325bb32ac7ad1eeccc23d966367e90a9edd
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-22\|World / Primary Cells by Cluster	TENM4 DPY19L1 ENC1 SORL1	9.43e-05	193	55	4	3b927d4b8ecb21a408424ef91a23746c21741f49
ToppCell	(4)_Endothelial_cells-(42)_EC-sinusoidal\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	MFNG SULT1A1 KANK3 ENC1	9.62e-05	194	55	4	4428b472c2042f88eae028b1770767512a515b75
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-intermediate_cap\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MFNG SULT1A4 SULT1A3 KANK3	9.82e-05	195	55	4	c0ea25ed1a849e6efff885e98013a4f1d5134758
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn\|World / Primary Cells by Cluster	TENM4 DPY19L1 ENC1 SORL1	1.00e-04	196	55	4	9401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCell	wk_08-11-Endothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MFNG SULT1A4 SULT1A3 KANK3	1.00e-04	196	55	4	0e545874083fd8e954a49fc397d57a86b081008b
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SRPK1 WDFY3 PFKFB3 SORL1	1.02e-04	197	55	4	340ce4fef244176fb52e38ffbcbdfda5ac3467dd
ToppCell	Enterocyte\|World / shred on cell type and cluster	SULT1A2 DHDH SULT1A1 CUBN	1.02e-04	197	55	4	1dd980fd066aef21694395a4b69df938501d9631
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM4 OLFML2B ENC1 FST	1.02e-04	197	55	4	9d7a1c7dc70ba5e35645f19f9e056e4fa2494aa0
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MFNG SULT1A4 SULT1A3 KANK3	1.02e-04	197	55	4	2ed92f942475db6836e48da3c6b8235eb8691c38
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM4 OLFML2B ENC1 FST	1.02e-04	197	55	4	090a251194da3e2806989d9a522588f83f52da7f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	MFNG TENM4 DPY19L1 ENC1	1.04e-04	198	55	4	6d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCell	C_01\|World / shred on cell type and cluster	SULT1A2 DHDH SULT1A1 CUBN	1.04e-04	198	55	4	71d38084d09a96331877384ce6346f0de4bdcef9
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	MFNG TENM4 DPY19L1 ENC1	1.04e-04	198	55	4	7943e4f67c3d6efb5c8b00aa0ff3cfe7be10c48d
ToppCell	wk_15-18-Hematologic-Myeloid-APOE+_Mac1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SULT1A2 SULT1A1 OLFML2B PLCE1	1.04e-04	198	55	4	88182ad964db88cf85b3e3a64929d07d59a923c2
ToppCell	Control-Control-Lymphocyte-T/NK-CD4+_T_activated\|Control / Disease, condition lineage and cell class	CHD6 PLEKHG5 CNTN2 SORL1	1.04e-04	198	55	4	ee71543559836fd59adc0da877b2ca538cba60cb
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SULT1A2 DHDH SULT1A1 CUBN	1.06e-04	199	55	4	0181c13379f869be47804cdb11bbdabcd30b9b23
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-OPC_related-Oligodendrocyte/OPC\|10w / Sample Type, Dataset, Time_group, and Cell type.	MFNG DHRS3 ENC1 FST	1.08e-04	200	55	4	345f1eac498cc87fd7bf08e7312608b2d6fe1dd7
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-OPC_related\|10w / Sample Type, Dataset, Time_group, and Cell type.	MFNG DHRS3 ENC1 FST	1.08e-04	200	55	4	8f5d98f962ddd8c4658c89ff8a2894de1228562a
ToppCell	severe-Myeloid-Neutrophils_4\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TDRD9 WDFY3 PFKFB3 SORL1	1.08e-04	200	55	4	b665f36dcf3c9d3981ee96f2973512f751612542
Drug	dopamine-4-O-sulfate	SULT1A2 SULT1A4 SULT1A1 SULT1A3	9.84e-10	7	54	4	CID000123932
Drug	2-naphthylsulfate	SULT1A2 SULT1A4 SULT1A1 SULT1A3	9.84e-10	7	54	4	CID000074428
Drug	2-iodo-4-azidophenol	SULT1A2 SULT1A4 SULT1A1 SULT1A3	9.84e-10	7	54	4	CID003035977
Drug	luciferyl sulfate	SULT1A2 SULT1A4 SULT1A1 SULT1A3	9.84e-10	7	54	4	CID011953812
Drug	2-iodophenol	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.96e-09	8	54	4	CID000010784
Drug	dopamine 3-O-sulfate	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.96e-09	8	54	4	CID000122136
Drug	6-anilino-2-thiouracil	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.96e-09	8	54	4	CID003037707
Drug	EM-139	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.99e-08	13	54	4	CID000131427
Drug	naphthalenemethanol	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.78e-08	14	54	4	CID000020908
Drug	deoxoestrone	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.78e-08	14	54	4	CID000005888
Drug	arylsulfate	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.78e-08	15	54	4	CID000074426
Drug	cyclobenzaprine	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.78e-08	15	54	4	CID000002895
Drug	A-44	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.03e-08	16	54	4	CID000120353
Drug	benzilic acid	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.57e-08	17	54	4	CID000006463
Drug	AC1Q6OHG	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.07e-07	19	54	4	CID000115063
Drug	pedunculagin	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.07e-07	19	54	4	CID000442688
Drug	PLP-Glu	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.33e-07	20	54	4	CID000444293
Drug	N-hydroxy-2-aminofluorene	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.64e-07	21	54	4	CID000005895
Drug	MeA alpha C	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.00e-07	22	54	4	CID000062244
Drug	AABSSN	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.00e-07	22	54	4	CID005464134
Drug	taselin	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.42e-07	23	54	4	CID000023846
Drug	AalphaC	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.90e-07	24	54	4	CID000062805
Drug	AzMC	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.44e-07	25	54	4	CID000064986
Drug	minoxidil sulphate	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.44e-07	25	54	4	CID000004202
Drug	2-pentanone	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.44e-07	25	54	4	CID000007895
Drug	alpha-methyldopamine	SULT1A2 SULT1A4 SULT1A1 SULT1A3	4.06e-07	26	54	4	CID000017005
Drug	glycolithocholic acid	SULT1A2 SULT1A4 SULT1A1 SULT1A3	4.06e-07	26	54	4	CID000115245
Drug	1m2q	SULT1A2 SULT1A4 SULT1A1 SULT1A3	4.06e-07	26	54	4	CID005326637
Drug	E)-4-hydroxytamoxifen	SULT1A2 SULT1A4 SULT1A1 SULT1A3 NDC80 GBE1 SOCS6	4.10e-07	197	54	7	CID000063062
Drug	phenylglyoxal	SULT1A2 SULT1A4 DHDH SULT1A1 SULT1A3 GBE1	4.17e-07	121	54	6	CID000014090
Drug	4-nonylphenol	SULT1A2 SULT1A4 SULT1A1 SULT1A3 FST	4.26e-07	64	54	5	CID000001752
Drug	Phosphoadenosine Phosphosulfate	SULT1A2 SULT1A1 SULT1A3	4.38e-07	7	54	3	ctd:D010724
Drug	Glu-P-2	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.42e-07	29	54	4	CID000049970
Drug	N-hydroxy-4-aminobiphenyl	SULT1A2 SULT1A1 SULT1A3	7.00e-07	8	54	3	ctd:C014593
Drug	3,3'-T2	SULT1A2 SULT1A4 SULT1A1 SULT1A3	7.40e-07	30	54	4	CID000065559
Drug	A2'p5'A2'p5'A	SULT1A2 SULT1A4 SULT1A1 SULT1A3	8.48e-07	31	54	4	CID000122642
Drug	acetaminophen sulfate	SULT1A2 SULT1A4 SULT1A1 SULT1A3	8.48e-07	31	54	4	CID000083939
Drug	barium hydroxide	SULT1A2 SULT1A4 SULT1A1 SULT1A3	8.48e-07	31	54	4	CID000028387
Drug	DCNP	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.10e-06	33	54	4	CID000012066
Drug	mefenamic acid	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.76e-06	37	54	4	CID000004044
Drug	phenylhydroxylamine	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.96e-06	38	54	4	CID000007518
Drug	catechol	SULT1A2 SULT1A4 DHDH SULT1A1 SULT1A3 NDC80 KEAP1	2.42e-06	257	54	7	CID000000289
Drug	d-equilenin	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.68e-06	41	54	4	CID000010597
Drug	L-alpha-methyldopa	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.96e-06	42	54	4	CID000004138
Drug	Woodward's reagent K	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.26e-06	43	54	4	CID000077804
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	DHRS3 HMGXB4 WDFY3 KEAP1 SOCS6 FST	3.37e-06	173	54	6	5950_DN
Drug	NSC674039	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.57e-06	44	54	4	CID000001249
Drug	1IIg	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.92e-06	45	54	4	CID000001682
Drug	NDPS	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.92e-06	45	54	4	CID000090363
Drug	1 C2	SULT1A2 SULT1A4 DHDH SULT1A1 SULT1A3	3.94e-06	100	54	5	CID005327152
Drug	4-octylphenol	SULT1A2 SULT1A4 SULT1A1 SULT1A3	4.67e-06	47	54	4	CID000015730
Drug	salicylamide	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.09e-06	48	54	4	CID000005147
Drug	sulfamethazine	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.09e-06	48	54	4	CID000005327
Drug	N-hydroxy-2-acetylaminofluorene	SULT1A2 SULT1A4 SULT1A1 SULT1A3	5.09e-06	48	54	4	CID000005896
Drug	5-hydroxymethylfurfural	SULT1A2 SULT1A1	5.52e-06	2	54	2	ctd:C008046
Drug	Hydroxytryptophol	SULT1A1 SULT1A3	5.52e-06	2	54	2	ctd:D006917
Drug	6-hydroxymelatonin	SULT1A1 SULT1A3	5.52e-06	2	54	2	ctd:C012365
Drug	9-hydroxybenzo(a)pyrene	SULT1A2 SULT1A4 SULT1A1 SULT1A3	7.59e-06	53	54	4	CID000028598
Drug	androstenediol	SULT1A2 SULT1A4 SULT1A1 SULT1A3	8.18e-06	54	54	4	CID000010634
Drug	minoxidil	SULT1A2 SULT1A4 SULT1A1 SULT1A3	8.18e-06	54	54	4	CID000004201
Drug	MeIQx	SULT1A2 SULT1A4 SULT1A1 SULT1A3	8.81e-06	55	54	4	CID000062275
Drug	NSC36919	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.09e-05	58	54	4	CID000235496
Drug	4-hydroxyestrone	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.17e-05	59	54	4	CID000018418
Drug	acetaminophen glucuronide	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.17e-05	59	54	4	CID000083944
Drug	sodium phosphate monohydrate	SULT1A2 SULT1A1 NDC80	1.40e-05	20	54	3	CID000061456
Drug	3-OHBaP	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.52e-05	63	54	4	CID000025890
Drug	5-hydroxy-3-methylindole	SULT1A2 SULT1A1	1.65e-05	3	54	2	CID000192734
Drug	5-hydroxyindole	SULT1A1 SULT1A3	1.65e-05	3	54	2	ctd:C026785
Drug	Minoxidil	SULT1A1 SULT1A3	1.65e-05	3	54	2	ctd:D008914
Drug	8-azaadenine	SULT1A1 SULT1A3	1.65e-05	3	54	2	ctd:C006654
Drug	3,3'-diiodothyronine	SULT1A1 SULT1A3	1.65e-05	3	54	2	ctd:C030629
Drug	epicatechin-3-gallate	SULT1A2 SULT1A4 SULT1A1 SULT1A3	1.72e-05	65	54	4	CID000065056
Drug	Pyrethroids	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.44e-05	71	54	4	CID000005053
Drug	adenylylsulfate	SULT1A2 SULT1A4 SULT1A1 SULT1A3	2.58e-05	72	54	4	CID000000228
Drug	7-hydroxycoumarin	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.03e-05	75	54	4	CID005281426
Drug	1,2,4-benzenetriol	DHDH DHRS3 KEAP1 SORL1	3.19e-05	76	54	4	CID000010787
Drug	Chebi:32701	SULT1A2 SULT1A1	3.30e-05	4	54	2	CID005460855
Drug	benzyloxyresorufin	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.54e-05	78	54	4	CID000114982
Drug	4-hydroxyestradiol	SULT1A2 SULT1A4 SULT1A1 SULT1A3	3.72e-05	79	54	4	CID000001743
Drug	reverse T3	SULT1A2 SULT1A4 SULT1A1 SULT1A3	4.31e-05	82	54	4	CID000022069
Drug	estrone-d4	SULT1A2 SULT1A4 SULT1A1 SULT1A3 NDC80	4.87e-05	168	54	5	CID000000698
Drug	harmol	SULT1A1 SULT1A3	5.50e-05	5	54	2	ctd:C001326
Drug	pinocembrin	SULT1A1 SULT1A3	5.50e-05	5	54	2	ctd:C016063
Drug	TKPP	SULT1A2 SULT1A1	5.50e-05	5	54	2	CID000023740
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	DHRS3 HMGXB4 KEAP1 SOCS6 FST	5.75e-05	174	54	5	5065_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	TENM4 HMGXB4 KEAP1 SOCS6 FST	5.91e-05	175	54	5	6736_DN
Drug	SAHA; Down 200; 10uM; PC3; HT_HG-U133A	NDC80 HMGXB4 KEAP1 SOCS6 FST	5.91e-05	175	54	5	1220_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	DHRS3 HMGXB4 WDFY3 KEAP1 ZNF639	6.07e-05	176	54	5	5976_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	NDC80 HMGXB4 WDFY3 KEAP1 FST	6.40e-05	178	54	5	5086_DN
Drug	4-aminobiphenyl	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.76e-05	92	54	4	CID000007102
Drug	p-nitroanisole	SULT1A2 SULT1A4 SULT1A1 SULT1A3	6.76e-05	92	54	4	CID000007485
Drug	2-naphthol	SULT1A2 SULT1A4 SULT1A1 SULT1A3	7.06e-05	93	54	4	CID000008663
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	NDC80 HMGXB4 KEAP1 SOCS6 FST	7.30e-05	183	54	5	7136_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	NDC80 HMGXB4 KEAP1 SOCS6 FST	7.88e-05	186	54	5	6874_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	TENM4 HMGXB4 KEAP1 SOCS6 FST	8.08e-05	187	54	5	6671_DN
Drug	2-Sulfotrehalose	SULT1A2 SULT1A1	8.23e-05	6	54	2	CID000124677
Drug	N-hydroxy-2-acetylaminophenanthrene	SULT1A2 SULT1A1	8.23e-05	6	54	2	CID000017102
Drug	1-naphthol	SULT1A2 SULT1A4 SULT1A1 SULT1A3	8.65e-05	98	54	4	CID000007005
Drug	adenosine 3'-5'-diphosphate	SULT1A2 SULT1A4 SULT1A1 SULT1A3	8.65e-05	98	54	4	CID000000073
Drug	Scopoletin [92-61-5]; Up 200; 20.8uM; MCF7; HT_HG-U133A	RTEL1 KANK3 FST TBL2 ZNF639	9.61e-05	194	54	5	6510_UP
Disease	gastric adenocarcinoma (is_implicated_in)	RTEL1 PLCE1	1.66e-04	11	52	2	DOID:3717 (is_implicated_in)
Disease	X-12707 measurement	SULT1A2 SULT1A1	1.99e-04	12	52	2	EFO_0800720
Disease	ascorbic acid 3-sulfate measurement	SULT1A2 SULT1A1	2.73e-04	14	52	2	EFO_0800173
Disease	Autosome Abnormalities	SULT1A2 SULT1A1	3.60e-04	16	52	2	C0004403
Disease	Chromosome Aberrations	SULT1A2 SULT1A1	3.60e-04	16	52	2	C0008625
Disease	Ischemic stroke, coronary artery disease	PHOX2A FST NT5C1B	5.80e-04	92	52	3	EFO_0001645, HP_0002140
Disease	cerebral amyloid deposition measurement	MUC19 WDFY3 NT5C1B	6.37e-04	95	52	3	EFO_0007707
Disease	fasting blood glucose change measurement	TENM4 PLCE1	1.46e-03	32	52	2	EFO_0010120
Disease	solar lentigines measurement	DHRS3 NT5C1B	1.46e-03	32	52	2	EFO_0007850
Disease	vitamin B12 measurement	ELAPOR2 CUBN	1.46e-03	32	52	2	EFO_0004620
Disease	word list delayed recall measurement, memory performance	TENM4 CHD6	1.55e-03	33	52	2	EFO_0004874, EFO_0006805
Disease	diet measurement	TENM4 DPY19L1 GBE1 CHD6 PFKFB3 TBL2 SORL1	2.33e-03	1049	52	7	EFO_0008111

Protein segments in the cluster

Peptide	Gene	Start	Entry
ATMFDGAKDMAYCDT	NT5C1B	446	Q96P26
FMCETCGKSFASKEY	GZF1	491	Q9H116
AFACKLDYDEDASAM	ST13P5	206	Q8NFI4
GCFKDISSITMFADY	C9orf64	226	Q5T6V5
LCGSYNNKAEDDFMS	MUC19	951	Q7Z5P9
EEACACDMEGKYLGF	MUC19	1496	Q7Z5P9
GADLYSLCSDAMTAA	PEX6	911	Q13608
SSPDYKDCNSAEAMD	PFKFB3	171	Q16875
TLLYTCAAEFDFMEK	DPY19L1	386	Q2PZI1
YASECAMKEAACSSG	FST	291	P19883
LGATECFLLAAMAYD	OR6Q1	111	Q8NGQ2
MAYDDSVKKEDCFDG	HMGXB4	1	Q9UGU5
KECTFSCASGEYLEM	ELAPOR2	101	A8MWY0
FMAKFSAEDLACGEI	CUBN	921	O60494
SADGLNMFDGTDSCY	GBE1	296	Q04446
DYFCAMFTSELSEKG	KLHL12	56	Q53G59
KSGLFACLDSVEMYF	KLHL28	291	Q9NXS3
YKDFLCTMDGSGALA	CCDC81	166	Q6ZN84
YGALMDEEDEGSKFC	CHD6	961	Q8TD26
SDEGKYTCFAENFMG	CNTN2	481	Q02246
DCNFDNGAGMSYEAK	DHDH	276	Q9UQ10
DADGATALMCASEYG	KANK3	726	Q6NY19
GAGDAVMYASTECKA	KEAP1	26	Q14145
IMGGDTEFSACSAYK	ENC1	496	O14682
IDYCTSKASAFAFME	DHRS3	186	O75911
CKMAAEFDTFLASGL	MFNG	121	O00587
ESCAGKMEEFFLFGA	OTOF	601	Q9HC10
EDKAISYSACAAQMF	OR5B17	86	Q8NGF7
LGAAECFLLSSMAYD	OR8H1	106	Q8NGG4
DYKGSDDFAALAACL	RTEL1	921	Q9NZ71
SCTREDYECDFGFKM	SORL1	676	Q92673
DYECDFGFKMSEDLS	SORL1	681	Q92673
MSATISCKEFADYFA	TDRD9	286	Q8NDG6
DKYFCFEGSCEKVDM	PLCE1	261	Q9P212
ATSSSKFYDLFLMEC	RHOBTB1	286	O94844
STACMAFELATGDYL	SRPK1	536	Q96SB4
GDYDKVKAMSEGSDC	OLFML2B	61	Q68BL8
FGTTECFLLAAMAYD	OR5T2	146	Q8NGG2
AAAAAFADKYMDTAG	HOXA13	201	P31271
FDADYAEKMAGCSLS	SULT1A4	276	P0DMN0
FDADYAEKMAGCSLS	SULT1A3	276	P0DMM9
GKDSKMDVYCFLFTD	PLEKHG5	596	O94827
DDCGKGFSSMLEYCK	ZNF639	406	Q9UID6
NMSSLELGDSALYFC	TRBV13	106	A0A0A6YYD4
EMFAGLSCFLKDSSD	WDFY3	281	Q8IZQ1
SEKDEDGFLYMVCAS	MAP1LC3B2	101	A6NCE7
DYDMFEVCFESKGTG	TMED10	101	P49755
FDADYAEKMAGCSLS	SULT1A1	276	P50225
FDADYAKKMAGCSLS	SULT1A2	276	P50226
SCVAAMEASAYGDFG	PHOX2A	11	O14813
FFAAYEATCGGDMNK	TLL2	456	Q9Y6L7
FAMELSSGDEFYIAC	TENM4	2346	Q6N022
FFAADELKGDNMYSC	USP20	546	Q9Y2K6
SDGSYARMKADECSG	ZNF12	156	P17014
SLFGSCYGKDMASCD	SOCS6	41	O14544
CYGKDMASCDINGED	SOCS6	46	O14544
MDFSSNGKYLATCAD	TBL2	96	Q9Y4P3
FFARDELKGDNMYSC	USP33	576	Q8TEY7
MALASFDDQYAGCAA	ART1	41	P52961
FDDQYAGCAAAMTAA	ART1	46	P52961
KCYESFMSGADSFDE	NDC80	231	O14777