Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	UBR2 ZNF133 MBTPS1 FOXK2 OBSCN TRIOBP NFASC XRCC5 TEP1 TRRAP ADCY3 DOCK5 NCOR2 LRFN2 CDK13 PLEKHG3 TBC1D1 SEMA3B PARD3 MLPH	5.72e-08	1489	112	20	28611215
Pubmed	Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer.	KLK15 KLK10 KLK9	1.30e-07	4	112	3	29095848
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	FOXM1 RBBP6 NCOR2 TDRD3 GSE1 DROSHA TSEN34 HELZ PLPBP TAF9 SCIN PRRC2B	4.64e-07	588	112	12	38580884
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FOXK2 ITPRIPL2 VWA8 KIF26A OBSCN TEP1 TRRAP PLEKHH3 C6orf132 NCOR2 TDRD3 CDK13 ZNF335 LRP3 MMP17 PRRC2B	5.28e-07	1105	112	16	35748872
Pubmed	Organization and evolution of the glandular kallikrein locus in Mus musculus.	KLK15 KLK10 KLK9	3.84e-06	10	112	3	12437987
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBR2 MBTPS1 ADCY3 LRFN2 TENM4 GSE1 TBC1D1 RHOBTB2 PRRC2B	7.16e-06	407	112	9	12693553
Pubmed	Human tissue kallikreins: physiologic roles and applications in cancer.	KLK15 KLK10 KLK9	9.08e-06	13	112	3	15192120
Pubmed	Epidermal growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1) suppressed the growth of hepatocellular carcinoma cells by promoting Semaphorin 3B(SEMA3B).	EFEMP1 SEMA3B	1.03e-05	2	112	2	30972979
Pubmed	PAR3-PAR6-atypical PKC polarity complex proteins in neuronal polarization.	PARD6A PARD3	1.03e-05	2	112	2	29696344
Pubmed	The FOXM1/BUB1B signaling pathway is essential for the tumorigenicity and radioresistance of glioblastoma.	FOXM1 BUB1B	1.03e-05	2	112	2	29039578
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	RBM42 MIDEAS NCOR2 GSE1 TAF9 PRRC2B	1.03e-05	152	112	6	38360978
Pubmed	Differences in Kallikrein-related peptidase mRNA sequences and KLK6 enzyme activity between mouse strains.	KLK15 KLK10 KLK9	1.15e-05	14	112	3	25666037
Pubmed	Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region.	KLK15 KLK10 KLK9	1.15e-05	14	112	3	11054574
Pubmed	Taxon-specific evolution of glandular kallikrein genes and identification of a progenitor of prostate-specific antigen.	KLK15 KLK10 KLK9	1.44e-05	15	112	3	15203212
Pubmed	Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3 , 2005.	KLK15 KLK10 KLK9	1.44e-05	15	112	3	16800723
Pubmed	A comprehensive nomenclature for serine proteases with homology to tissue kallikreins.	KLK15 KLK10 KLK9	1.44e-05	15	112	3	16800724
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	FOXK2 NCSTN ECM1 SYDE1 HSF5 PLEKHH3 TBC1D1 ZNF335 MMP17 PRRC2B SEZ6	1.46e-05	689	112	11	36543142
Pubmed	Blood biomarker levels to aid discovery of cancer-related single-nucleotide polymorphisms: kallikreins and prostate cancer.	KLK15 KLK10 KLK9	1.77e-05	16	112	3	20424135
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CCDC8 RRM2 SYDE1 C6orf132 SAMD11 PLEKHG3 TBC1D1 BUB1B OSBPL6 MAP3K9 HELZ PARD3	2.25e-05	861	112	12	36931259
Pubmed	Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.	PARD6A PARD3	3.08e-05	3	112	2	21170030
Pubmed	Shp2 promotes metastasis of prostate cancer by attenuating the PAR3/PAR6/aPKC polarity protein complex and enhancing epithelial-to-mesenchymal transition.	PARD6A PARD3	3.08e-05	3	112	2	26050620
Pubmed	Biochemical and functional characterization of the human tissue kallikrein 9.	KLK10 KLK9	3.08e-05	3	112	2	28559305
Pubmed	Increased BUB1B/BUBR1 expression contributes to aberrant DNA repair activity leading to resistance to DNA-damaging agents.	FOXM1 BUB1B	3.08e-05	3	112	2	34545188
Pubmed	TWEAK promotes migration and invasion in MEFs through a mechanism dependent on ERKs activation and Fibulin 3 down-regulation.	TNFSF12 EFEMP1	3.08e-05	3	112	2	28383766
Pubmed	The PAR-aPKC system: lessons in polarity.	PARD6A PARD3	3.08e-05	3	112	2	16525119
Pubmed	Loss of APKC expression independently predicts tumor recurrence in superficial bladder cancers.	PARD6A PARD3	3.08e-05	3	112	2	21549621
Pubmed	Functional Variants in Notch Pathway Genes NCOR2, NCSTN, and MAML2 Predict Survival of Patients with Cutaneous Melanoma.	NCSTN NCOR2	3.08e-05	3	112	2	25953768
Pubmed	Hook2, a microtubule-binding protein, interacts with Par6α and controls centrosome orientation during polarized cell migration.	PARD6A PARD3	3.08e-05	3	112	2	27624926
Pubmed	Nuclear movement during myotube formation is microtubule and dynein dependent and is regulated by Cdc42, Par6 and Par3.	PARD6A PARD3	3.08e-05	3	112	2	22732842
Pubmed	ECM1 interacts with fibulin-3 and the beta 3 chain of laminin 332 through its serum albumin subdomain-like 2 domain.	ECM1 EFEMP1	3.08e-05	3	112	2	19275936
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DHX57 SYDE1 DOCK5 EFEMP1 GSE1 CDK13 DROSHA BUB1B HELZ PRRC2B	4.97e-05	650	112	10	38777146
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	RBBP6 KPRP XRCC5 MIDEAS NCOR2 MISP GSE1 CDK13 HELZ PRRC2B	5.30e-05	655	112	10	35819319
Pubmed	Human eye development is characterized by coordinated expression of fibrillin isoforms.	FBN2 EFEMP1	6.14e-05	4	112	2	25406291
Pubmed	G-protein-activated phospholipase C-beta, new partners for cell polarity proteins Par3 and Par6.	PARD6A PARD3	6.14e-05	4	112	2	15782111
Pubmed	Cloning and expression of mouse Cadherin-7, a type-II cadherin isolated from the developing eye.	INPP5D MLPH	6.14e-05	4	112	2	10433813
Pubmed	Par-complex proteins promote proliferative progenitor divisions in the developing mouse cerebral cortex.	PARD6A PARD3	6.14e-05	4	112	2	18032449
Pubmed	BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.	NCOR2 GSE1 PRRC2B	6.26e-05	24	112	3	33722704
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	VWA8 RBBP6 TEP1 TRRAP NCOR2 ZNF526 FBN2 GSE1 DROSHA HELZ TAF9 PARD3 PRRC2B	6.43e-05	1116	112	13	31753913
Pubmed	Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition.	PARD6A PARD3 CNTN2	8.99e-05	27	112	3	27178982
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	FOXK2 RBBP6 RBM42 TRIOBP DHX57 TRRAP MFF C6orf132 TDRD3 CDK13 PLEKHG3 DROSHA HELZ TAF9 PARD3	9.35e-05	1497	112	15	31527615
Pubmed	Loss of aPKCλ in differentiated neurons disrupts the polarity complex but does not induce obvious neuronal loss or disorientation in mouse brains.	PARD6A PARD3	1.02e-04	5	112	2	24391875
Pubmed	A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers.	FOXM1 BUB1B	1.02e-04	5	112	2	20531406
Pubmed	An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms.	PARD6A PARD3	1.02e-04	5	112	2	19142224
Pubmed	Neuropilin2 regulates the guidance of post-crossing spinal commissural axons in a subtype-specific manner.	SEMA3B CNTN2	1.02e-04	5	112	2	23902858
Pubmed	The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1.	PARD6A PARD3	1.02e-04	5	112	2	10954424
Pubmed	The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth.	PARD6A PARD3	1.02e-04	5	112	2	17101696
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	FOXK2 RRM2 MIDEAS NCOR2 GSE1 HELZ NIT1 PRRC2B	1.21e-04	457	112	8	32344865
Pubmed	Control of developmentally primed erythroid genes by combinatorial co-repressor actions.	TRRAP NCOR2 GSE1	1.24e-04	30	112	3	26593974
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	USP17L12 KIF21A OBSCN NFASC XRCC5 DOCK5 TDRD3 GSE1 DROSHA MAP3K9	1.38e-04	736	112	10	29676528
Pubmed	A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity.	PARD6A PARD3	1.53e-04	6	112	2	10934475
Pubmed	ARAP, a Novel Adaptor Protein, Is Required for TCR Signaling and Integrin-Mediated Adhesion.	LCP2 FYB2	1.53e-04	6	112	2	27335501
Pubmed	The new human kallikrein gene family: implications in carcinogenesis.	KLK15 KLK10	1.53e-04	6	112	2	10675891
Pubmed	The signaling adaptor GAB1 regulates cell polarity by acting as a PAR protein scaffold.	PARD6A PARD3	1.53e-04	6	112	2	22883624
Pubmed	PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions.	PARD6A PARD3	2.14e-04	7	112	2	12459187
Pubmed	Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activity.	PARD6A PARD3	2.14e-04	7	112	2	15254234
Pubmed	Association of TAG-1 with Caspr2 is essential for the molecular organization of juxtaparanodal regions of myelinated fibers.	NFASC CNTN2	2.14e-04	7	112	2	12975355
Pubmed	Association of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cells.	PARD6A PARD3	2.84e-04	8	112	2	12203721
Pubmed	Genetic, morphometric, and behavioral factors linked to the midsagittal area of the corpus callosum.	VWA8 TDRD3	2.84e-04	8	112	2	22666227
Pubmed	Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C.	PARD6A PARD3	2.84e-04	8	112	2	11260256
Pubmed	Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation.	INPP5D LCP2	2.84e-04	8	112	2	22267732
Pubmed	Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal.	XRCC5 KCTD17 NCOR2	3.41e-04	42	112	3	27465491
Pubmed	Active suppression of interneuron programs within developing motor neurons revealed by analysis of homeodomain factor HB9.	FOXM1 CNTN2	3.65e-04	9	112	2	10482235
Pubmed	Phosphatidylinositol-3-kinase-atypical protein kinase C signaling is required for Wnt attraction and anterior-posterior axon guidance.	PARD6A CNTN2	3.65e-04	9	112	2	18367611
Pubmed	Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity.	PARD6A PARD3	3.65e-04	9	112	2	18562307
Pubmed	MBTPS1/SKI-1/S1P proprotein convertase is required for ECM signaling and axial elongation during somitogenesis and vertebral development†.	MBTPS1 FBN2	3.65e-04	9	112	2	25652402
Pubmed	GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.	PARD6A PARD3	3.65e-04	9	112	2	23446420
Pubmed	Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures.	PARD6A PARD3	3.65e-04	9	112	2	11257119
Pubmed	TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9.	TRRAP TAF9	3.65e-04	9	112	2	15899866
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	VWA8 ADCY3 PLEKHG3 PRRC2B	3.79e-04	105	112	4	9628581
Pubmed	Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.	MIDEAS NCOR2 GSE1	4.18e-04	45	112	3	21258344
Pubmed	Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates.	TRRAP TAF9	4.55e-04	10	112	2	9880483
Pubmed	Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells.	TRRAP NCOR2	4.55e-04	10	112	2	12738788
Pubmed	The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42.	PARD6A PARD3	4.55e-04	10	112	2	10934474
Pubmed	TGF-beta signaling specifies axons during brain development.	PARD6A CNTN2	4.55e-04	10	112	2	20603020
Pubmed	Cell polarity and spindle orientation in the distal epithelium of embryonic lung.	PARD6A PARD3	4.55e-04	10	112	2	21246661
Pubmed	Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation.	TRRAP TAF9	4.55e-04	10	112	2	17694077
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	RBM42 TRRAP NCOR2 PRRC2B	5.53e-04	116	112	4	30804394
Pubmed	The 400 kDa subunit of the PCAF histone acetylase complex belongs to the ATM superfamily.	TRRAP TAF9	5.55e-04	11	112	2	9885574
Pubmed	c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation.	TRRAP TAF9	5.55e-04	11	112	2	12660246
Pubmed	Cilia proteins control cerebellar morphogenesis by promoting expansion of the granule progenitor pool.	ADCY3 CNTN2	5.55e-04	11	112	2	17804638
Pubmed	Multivalent binding of p53 to the STAGA complex mediates coactivator recruitment after UV damage.	TRRAP TAF9	5.55e-04	11	112	2	18250150
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	ITPRIPL2 CYP24A1 OBSCN NCSTN NCOR2 ANOS1 FBN2 SAMD11 PLEKHG3 TSEN34 CNTN2 PRRC2B	5.57e-04	1215	112	12	15146197
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	UBR2 CCDC8 TRIOBP NCOR2 TDRD3 GSE1 PTPRN SSH3 HELZ SCIN PRRC2B	5.85e-04	1049	112	11	27880917
Pubmed	A role for Nr-CAM in the patterning of binocular visual pathways.	NFASC CNTN2	6.64e-04	12	112	2	16701205
Pubmed	Human transcription factor protein interaction networks.	CCDC8 FOXK2 RBBP6 XRCC5 MIDEAS TRRAP NCOR2 FBN2 GSE1 SAMD11 HELZ TAF9 PRRC2B	7.02e-04	1429	112	13	35140242
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	XRCC5 MIDEAS TRRAP NCOR2 GSE1	7.50e-04	220	112	5	35785414
Pubmed	Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration.	TRRAP TAF9	7.83e-04	13	112	2	15932940
Pubmed	CNS myelin paranodes require Nkx6-2 homeoprotein transcriptional activity for normal structure.	NFASC CNTN2	7.83e-04	13	112	2	15601927
Pubmed	A distinct PAR complex associates physically with VE-cadherin in vertebrate endothelial cells.	PARD6A PARD3	7.83e-04	13	112	2	17057644
Pubmed	Stability of the cancer target DDIAS is regulated by the CHIP/HSP70 pathway in lung cancer cells.	ECM1 EFEMP1	7.83e-04	13	112	2	28079882
Pubmed	GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer.	DHX57 XRCC5 MIDEAS KCTD17 SEMA3B	7.97e-04	223	112	5	33731348
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	RBM42 TEP1 ECM1 EFEMP1 PTPRN NIT1 TAF9 PRRC2B	8.07e-04	608	112	8	16713569
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TRIOBP NFASC TENM4 TBC1D1 RHOBTB2	8.29e-04	225	112	5	12168954
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	FOXK2 RBBP6 MIDEAS TRRAP MISP GSE1	8.51e-04	341	112	6	32971831
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	FOXK2 KPRP RRM2 MIDEAS MISP BUB1B PLPBP	8.64e-04	472	112	7	38943005
Pubmed	Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.	DHX57 TRRAP	9.12e-04	14	112	2	28263302
Pubmed	Epicardial spindle orientation controls cell entry into the myocardium.	PARD6A PARD3	9.12e-04	14	112	2	20643355
Pubmed	P53 independent pathogenic mechanisms contribute to BubR1 microcephaly.	FOXM1 BUB1B	9.12e-04	14	112	2	37900274
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FOXM1 RBBP6 TRRAP NCOR2 GSE1 CDK13 ZNF335 HELZ PARD3	9.15e-04	774	112	9	15302935
Pubmed	Interaction network of human early embryonic transcription factors.	FOXK2 KPRP MIDEAS NCOR2 GSE1 PRRC2B	9.88e-04	351	112	6	38297188
Interaction	CLEC11A interactions	MBTPS1 VWA8 PLEKHH3 MISP DROSHA SEMA3B PRRC2B	7.40e-07	96	106	7	int:CLEC11A
GeneFamily	Kallikreins	KLK15 KLK10 KLK9	2.51e-05	16	66	3	616
GeneFamily	Fibronectin type III domain containing	OBSCN NFASC ANOS1 LRFN2 CNTN2	2.95e-04	160	66	5	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	OBSCN NFASC LRFN2 ALPK3 CNTN2	3.03e-04	161	66	5	593
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SH2D3A C6orf132 DOCK5 EFEMP1 SH3RF2 SEMA3B MAP3K9 PARD3	2.45e-08	188	111	8	43a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KIF21A SH2D3A MISP ANOS1 EFEMP1 SH3RF2 PLEKHG3	6.63e-07	198	111	7	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	distal-Epithelial-Alveolar_Epithelial_Type_1-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK10 C6orf132 MISP ANOS1 EFEMP1 RHOBTB2 SEMA3B	6.86e-07	199	111	7	c1daa481f88d5281b6b5ea8ec8bb70cc0907d613
ToppCell	distal-2-Epithelial-Alveolar_Epithelial_Type_1\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK10 C6orf132 MISP ANOS1 EFEMP1 RHOBTB2 SEMA3B	7.09e-07	200	111	7	313ec1e53bd738a9cb48dc5b946261156f99f44b
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	PLEKHH3 MISP EFEMP1 SH3RF2 SEMA3B SHOC1	4.65e-06	172	111	6	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITPRIPL2 PLEKHA6 LCP2 TBC1D1 MAP3K9 MMP17	5.13e-06	175	111	6	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	FOXM1 KIF26A RRM2 SH3RF2 BUB1B SCIN	5.13e-06	175	111	6	fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|368C / Donor, Lineage, Cell class and subclass (all cells)	FOXM1 KIF26A RRM2 SH3RF2 BUB1B SCIN	5.13e-06	175	111	6	36c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SH2D3A MISP ANOS1 EFEMP1 SH3RF2 SEMA3B	6.22e-06	181	111	6	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	wk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL27A1 KCTD17 FBN2 TENM4 SCIN MLPH	6.42e-06	182	111	6	03a5a02acd48f0eb210485348bfe0cd21f486215
ToppCell	droplet-Spleen-nan-24m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXM1 DXO RRM2 PLEKHH3 GPR62 BUB1B	6.84e-06	184	111	6	b998803180322a5ea2b567928dea531c26816c3c
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|343B / Donor, Lineage, Cell class and subclass (all cells)	KLK10 NCOR2 MISP ANOS1 SEMA3B SHOC1	6.84e-06	184	111	6	cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	KLK10 NCOR2 MISP ANOS1 SEMA3B SHOC1	6.84e-06	184	111	6	bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITPRIPL2 KIF21A TBC1D1 SHOC1 SCIN FYB2	7.50e-06	187	111	6	7b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	VWA8 KIF21A OBSCN FBN2 SH3RF2 FYB2	7.50e-06	187	111	6	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	Adult\|World / Lineage, Cell type, age group and donor	LCP2 NCOR2 SH3RF2 RHOBTB2 MLPH FYB2	7.97e-06	189	111	6	5cd285bfad973125d46d704fec18b21266a63379
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	CCDC8 INPP5D COL27A1 ADCY3 SYDE1 KCTD17	9.52e-06	195	111	6	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	distal-Epithelial-Alveolar_Epithelial_Type_1-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK10 MISP EFEMP1 SH3RF2 RHOBTB2 SEMA3B	9.80e-06	196	111	6	b74dbdfc8d9b85d7cae5c6a49b56347b15ce16e1
ToppCell	distal-1-Epithelial-Alveolar_Epithelial_Type_1\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK10 MISP EFEMP1 SH3RF2 RHOBTB2 SEMA3B	1.01e-05	197	111	6	d44b7dc7c6416ed9466889374c3ae39f43ac8bb6
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	TOGARAM2 ECM1 C6orf132 SCIN DNAH9 FYB2	1.04e-05	198	111	6	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	KIF21A SH2D3A MISP ANOS1 FBN2 EFEMP1	1.04e-05	198	111	6	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	TOGARAM2 ECM1 C6orf132 SCIN DNAH9 FYB2	1.04e-05	198	111	6	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	Control_saline-Epithelial_alveolar-AT_1\|Control_saline / Treatment groups by lineage, cell group, cell type	KIF21A SH2D3A MISP ANOS1 FBN2 EFEMP1	1.04e-05	198	111	6	9b161285df7a4e51618f3517cfc5b8221ba55786
ToppCell	medial-2-Epithelial-Alveolar_Epithelial_Type_1\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK10 C6orf132 MISP ANOS1 RHOBTB2 SEMA3B	1.07e-05	199	111	6	456460c761e26ed4b1d88d9bee4d2a7c9bd9d416
ToppCell	medial-Epithelial-Alveolar_Epithelial_Type_1-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK10 C6orf132 MISP ANOS1 RHOBTB2 SEMA3B	1.07e-05	199	111	6	5263338242f95c04690d0795749ccc20b0d19f7a
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KIF21A SH2D3A MISP ANOS1 EFEMP1 SH3RF2	1.07e-05	199	111	6	a270630626df614f8605abddb7dee7c4d74f6149
ToppCell	medial-Epithelial-Alveolar_Epithelial_Type_1\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK10 C6orf132 MISP ANOS1 RHOBTB2 SEMA3B	1.07e-05	199	111	6	c11365653c69a5dfb37946231f8af05149a61a71
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FOXM1 KLK10 RRM2 PLEKHH3 MISP DMRTA2	1.07e-05	199	111	6	fe22833e69928a1478df265e1c356c463611dedd
ToppCell	normal_Pleural_Fluid-Epithelial_cells\|normal_Pleural_Fluid / Location, Cell class and cell subclass	C6orf132 MISP EFEMP1 SEMA3B PARD3 MLPH	1.07e-05	199	111	6	564ba7acd03be2d6e4d0850cb2c7237a788dc275
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	KIF21A SH2D3A MISP ANOS1 EFEMP1 SH3RF2	1.10e-05	200	111	6	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CYP24A1 OBSCN ANOS1 TENM4 SH3RF2 DMRTA2	1.10e-05	200	111	6	8827653738a931e4a4545e0c7d75be12bed40740
ToppCell	distal-Epithelial-Alveolar_Epithelial_Type_1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK10 MISP ANOS1 EFEMP1 RHOBTB2 SEMA3B	1.10e-05	200	111	6	cbe3e107ac16c17687d73ebb04c39d51aba1fa98
ToppCell	distal-Epithelial-Basal-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK10 CYP24A1 SH2D3A MISP SEMA3B DMRTA2	1.10e-05	200	111	6	6f00d08e93f89b3575ebbd5c2f451e655d449ef3
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Cplx3_(Deep_layer_pyramidal_cells--Cortical_Subplate)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	INHBE SOX30 CYP24A1 FYB2	4.35e-05	78	111	4	869fcbc0c308164101c0e4e0494c6a75c2f6f94e
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Cplx3_(Deep_layer_pyramidal_cells--Cortical_Subplate)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	INHBE SOX30 CYP24A1 FYB2	4.35e-05	78	111	4	46e31ebb3afc08bf414a5793cd9b4320bf4375c5
ToppCell	PBMC-Severe-cDC_4\|Severe / Compartment, Disease Groups and Clusters	ECM1 FBN2 LRP3 MMP17 INKA1	5.05e-05	160	111	5	4dac64e58d9366c399f3d830848ccb720d400be7
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCDC8 COL27A1 RRM2 TENM4 SPON2	5.36e-05	162	111	5	3f264263878af630921911c2b344ac56eb1e7099
ToppCell	10x5'-bone_marrow-Lymphocytic_B_plasma-Plasmablasts\|bone_marrow / Manually curated celltypes from each tissue	FOXM1 INHBE UTS2R NLRP7 RRM2	5.68e-05	164	111	5	67260e9f569f0acaeb0e65f69cde230f91cd3d26
ToppCell	Dividing_Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	FOXM1 RRM2 HSF5 PARD6A BUB1B	6.02e-05	166	111	5	c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLK10 NLRP7 NFASC RRM2 ANOS1	6.02e-05	166	111	5	7495961adcefe5c1fb288913b1a5236328a04703
ToppCell	Basal_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	CYP24A1 SH2D3A C6orf132 PLEKHG3 CNTN2	6.02e-05	166	111	5	aea2ae12e4746149ebc6da063ef694381c098f80
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF21A TBC1D1 SHOC1 SCIN FYB2	6.55e-05	169	111	5	2a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCell	droplet-Thymus-nan-18m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MISP EFEMP1 SEMA3B HS3ST2 MLPH	6.55e-05	169	111	5	4ac21e8199de4b6917eacadc56fffc6d886ee643
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITPRIPL2 OBSCN LCP2 DOCK5 PTPRN	6.92e-05	171	111	5	355a27ea88410a84210f7e4298c7c4f90cf2f8a9
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FOXM1 RRM2 ANOS1 BUB1B OSBPL6	6.92e-05	171	111	5	4ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	FOXK2 TRRAP ADCY3 SEMA3B INKA1	7.12e-05	172	111	5	da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCell	facs-Heart-LV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY3 PLEKHH3 LRFN2 PLEKHG3 TBC1D1	7.31e-05	173	111	5	d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF21A TBC1D1 SHOC1 SCIN FYB2	7.31e-05	173	111	5	0bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell	facs-Heart-LV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY3 PLEKHH3 LRFN2 PLEKHG3 TBC1D1	7.31e-05	173	111	5	3c852ffe22f4a5b632463086b08c669310684e80
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLK10 RPS6KA4 OBSCN RRM2 SH3RF2	7.52e-05	174	111	5	207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF21A TBC1D1 SHOC1 SCIN FYB2	8.15e-05	177	111	5	8e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCell	droplet-Limb_Muscle-nan-21m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL27A1 C6orf132 SEMA3B KLK9 INKA1	8.15e-05	177	111	5	291231b1520c135e92739e201495fe1935efa927
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	ANOS1 SH3RF2 RHOBTB2 SEMA3B PARD3	8.59e-05	179	111	5	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	KLK10 MISP ANOS1 RHOBTB2 SEMA3B	8.59e-05	179	111	5	d5763912a4ce7188535675e338799b856edb9dda
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-basal_late\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KLK10 CYP24A1 SH2D3A ANOS1 EFEMP1	8.82e-05	180	111	5	255097d8eb244a32eb2ecd0e7e48e1a20bafb5cd
ToppCell	367C-Myeloid-Mast_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	TDRD3 OSBPL6 SCIN MLPH INKA1	9.05e-05	181	111	5	063fc83870f55f63c013f0276c1ec8f3abcbcf27
ToppCell	367C-Myeloid-Mast_cell-\|367C / Donor, Lineage, Cell class and subclass (all cells)	TDRD3 OSBPL6 SCIN MLPH INKA1	9.05e-05	181	111	5	e1161c9828ee94518eb5bef0b6228d71299c2f59
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating-Lymphatic_EC_proliferating_L.2.5.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FOXM1 C16orf78 RRM2 KCTD17 BUB1B	9.29e-05	182	111	5	f703963b5d1e8c1f95d78807521048553b0792d8
ToppCell	PBMC-Control-cDC_12\|Control / Compartment, Disease Groups and Clusters	FOXM1 RRM2 ADCY3 BUB1B SEMA3B	9.29e-05	182	111	5	4774066d0f9986abc3d13a2a3bc99ce4f1327ae0
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FOXM1 C16orf78 RRM2 KCTD17 BUB1B	9.29e-05	182	111	5	ebd177ad5eac51bf2db0657596618bdf1e5d46e1
ToppCell	IPF-Epithelial-ATI\|World / Disease state, Lineage and Cell class	MISP EFEMP1 SH3RF2 RHOBTB2 SEMA3B	9.53e-05	183	111	5	31fef35ecf30162662f24d335d8f0cceacc07039
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A ANOS1 EFEMP1 SH3RF2 SEMA3B	9.53e-05	183	111	5	ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCell	Control-T/NK_proliferative\|Control / Disease group and Cell class	FOXM1 RRM2 ECM1 BUB1B MMP17	9.53e-05	183	111	5	09c2b4e630f1c338f02c1242e3598e870d6b0a28
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 SHROOM4 PLEKHG3 SEMA3B CNTN2	9.53e-05	183	111	5	93213124e55d1b673dd345188caf8b5bd31d99fe
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 SHROOM4 PLEKHG3 SEMA3B CNTN2	9.78e-05	184	111	5	f6d6b3ddada66dae28d3306415bf4efe0934208a
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN FBN2 TENM4 DNAH9 CNTN2	9.78e-05	184	111	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN FBN2 TENM4 DNAH9 CNTN2	9.78e-05	184	111	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A ANOS1 EFEMP1 SH3RF2 SEMA3B	9.78e-05	184	111	5	cdf6f1c6cce97a7effa0c55959652e2c0b6992b3
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN FBN2 TENM4 DNAH9 CNTN2	9.78e-05	184	111	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Fat-Scat-21m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ECM1 FBN2 EFEMP1 SPON2 SEMA3B	1.00e-04	185	111	5	01bbe1e09f9ccae837a03ea2cdd168fa10800942
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLK10 ECM1 C6orf132 MISP KLK9	1.00e-04	185	111	5	f3fbc3096f85397a959cee17c3c4fcf2d511f3d5
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFSF12 KIF26A SYDE1 KCTD17 NCOR2	1.00e-04	185	111	5	60206c7322b4ddb2010040aac70561df842c9843
ToppCell	LPS_only-Epithelial_alveolar-AT_1-AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF21A MISP EFEMP1 SH3RF2 SEMA3B	1.00e-04	185	111	5	0c247a3f394c42e2a6f67fee3d9cf33096fecd13
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 SHROOM4 PLEKHG3 SEMA3B CNTN2	1.00e-04	185	111	5	1d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCell	Control-T_cells-NK_cells\|Control / group, cell type (main and fine annotations)	NLRP7 INPP5D LRFN2 PLEKHG3 SPON2	1.00e-04	185	111	5	755c0998c729f462399f1d5e88adf4bfae31be30
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 SHROOM4 PLEKHG3 SEMA3B CNTN2	1.00e-04	185	111	5	b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 SHROOM4 PLEKHG3 SEMA3B CNTN2	1.03e-04	186	111	5	90eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 SHROOM4 PLEKHG3 SEMA3B CNTN2	1.03e-04	186	111	5	bd8a9753df219084e19e7f94447856e86608325c
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 SHROOM4 PLEKHG3 SEMA3B CNTN2	1.05e-04	187	111	5	f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCell	AT1_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	MISP ANOS1 EFEMP1 SH3RF2 SEMA3B	1.05e-04	187	111	5	f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCell	367C-Myeloid-Mast_cell\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TDRD3 OSBPL6 SCIN MLPH INKA1	1.05e-04	187	111	5	7d416693cb719df4197a11acc6b4e19171352515
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 SHROOM4 PLEKHG3 SEMA3B CNTN2	1.05e-04	187	111	5	b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCell	367C-Myeloid-Mast_cell-\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TDRD3 OSBPL6 SCIN MLPH INKA1	1.05e-04	187	111	5	b1341d272d9fc07c6f7590d6d398d7a5cf42240b
ToppCell	TCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	KLK10 KPRP C6orf132 SH3RF2 KLK9	1.05e-04	187	111	5	2ca7928baf0c5e61f7294ed05e6e6f0e0adf9d3f
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 SHROOM4 PLEKHG3 SEMA3B CNTN2	1.08e-04	188	111	5	14072d0b82df55711d5356b2209f4f0bdd90dc27
ToppCell	droplet-Fat-Scat-21m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ECM1 FBN2 EFEMP1 SPON2 SEMA3B	1.08e-04	188	111	5	e54e09d34e263d5709c337914809e61e74e20591
ToppCell	droplet-Fat-Scat-21m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ECM1 FBN2 EFEMP1 SPON2 SEMA3B	1.08e-04	188	111	5	7fc9810ab14354cb512e2b1285562009c10203f5
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	OBSCN NFASC ADCY3 SYDE1 OSBPL6	1.08e-04	188	111	5	ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCell	ASK454-Epithelial-Type_1\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	FOXM1 ITPRIPL2 ANOS1 EFEMP1 SEMA3B	1.08e-04	188	111	5	13f8ce8f24ac7d7ed87f4ae3b8f4096de29383c2
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 SHROOM4 PLEKHG3 SEMA3B CNTN2	1.08e-04	188	111	5	b04fd6a724c117eb9a979c29b91f90113feb7a5c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KLK10 EFEMP1 SEMA3B MLPH FYB2	1.08e-04	188	111	5	9655a4c47b644a870017d349b99063e17dbae572
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 SHROOM4 PLEKHG3 SEMA3B CNTN2	1.08e-04	188	111	5	d9692b6048d9b85524a07a1807bdd4757731c151
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	KIF21A RRM2 SPON2 PARD3 DNAH9	1.08e-04	188	111	5	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	wk_08-11-Epithelial-PNS-MFNG+_DBH+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	UTS2R KIF21A NFASC MMP17 SEZ6	1.08e-04	188	111	5	d3d7d21d4fa39ac4106a164652673de1bef8662d
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 SHROOM4 PLEKHG3 SEMA3B CNTN2	1.11e-04	189	111	5	70eea8c94fa56bb15bee8065de47acea156794e9
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	VWA8 KIF21A OBSCN SH3RF2 FYB2	1.11e-04	189	111	5	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK5 SHROOM4 PLEKHG3 SEMA3B CNTN2	1.11e-04	189	111	5	b60c8a29d3169c4830fe63b01db90c57660fc239
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	OBSCN LCP2 ANOS1 FBN2 PARD3	1.14e-04	190	111	5	3b8d1e66ae68c1eee64095e75195d76d97e24026
ToppCell	TCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	KLK10 KPRP C6orf132 SH3RF2 KLK9	1.14e-04	190	111	5	3188c7bd225cbcf46a21e2fb784336cdd9665995
ToppCell	TCGA-Skin-Primary_Tumor\|TCGA-Skin / Sample_Type by Project: Shred V9	KLK10 KPRP C6orf132 SH3RF2 KLK9	1.14e-04	190	111	5	e2b26a03c6ab24d9b0f4150c47597be37767d86e
Disease	kallikrein-8 measurement	KLK10 KLK9	1.90e-04	6	106	2	EFO_0020516
Disease	contactin-2 measurement	NFASC CNTN2	1.90e-04	6	106	2	EFO_0008100
Disease	renin measurement	PLEKHA6 CNTN2	3.53e-04	8	106	2	EFO_0010616
Disease	rectum cancer (is_implicated_in)	CYP24A1 XRCC5	4.53e-04	9	106	2	DOID:1993 (is_implicated_in)
Disease	uterine prolapse	FBN2 EFEMP1	1.48e-03	16	106	2	EFO_1001864
Disease	Microcephaly	TRRAP BUB1B TSEN34	1.83e-03	67	106	3	C0025958
Disease	lung cancer (is_implicated_in)	SOX30 CYP24A1 HS3ST2	2.43e-03	74	106	3	DOID:1324 (is_implicated_in)
Disease	Lung Neoplasms	FOXM1 SOX30 CYP24A1 TEP1 EFEMP1	2.73e-03	265	106	5	C0024121
Disease	Malignant neoplasm of lung	FOXM1 SOX30 CYP24A1 TEP1 EFEMP1	2.77e-03	266	106	5	C0242379
Disease	QT interval	DXO DOCK5 CDK13 SPON2 OSBPL6 ALPK3 PRRC2B	3.19e-03	534	106	7	EFO_0004682

Protein segments in the cluster

Peptide	Gene	Start	Entry
ADPPRVLAQRRPLAV	BUB1B	546	O60566
VQDSRFPPLNLQRPV	GSE1	191	Q14687
SLTPQPTRPFNRKRF	ALPK3	671	Q96L96
PESTQRPNPFRRQSI	C16orf78	141	Q8WTQ4
PRQRTPLDILTRVFP	DMRTA2	311	Q96SC8
RKRRRFLSPQQPPLL	CDK13	26	Q14004
RAAVAPQRAPILRPA	RBM42	146	Q9BTD8
PLPPSSLQRFLRARN	NCSTN	421	Q92542
TFRNRRSLLLPPPPF	PABIR3	56	Q6P4D5
TQLPFQRRRPTRPLE	ANOS1	416	P23352
LRPLRFRAPDEPQQA	MISP	506	Q8IVT2
PQRRRPSLLSEFQPG	NCOR2	61	Q9Y618
PPQPRRARRLLFAFT	HS3ST2	11	Q9Y278
RPAPSAQPLRRQCLS	INKA1	116	Q96EL1
LAQELPAPSRARVPR	PTPRN	281	Q16849
FVVARRAALRPPRPA	GPR62	196	Q9BZJ7
VLPNFRSNRPQVRPL	MBTPS1	961	Q14703
PRNKISRFQAPISAP	MFF	181	Q9GZY8
VFQRRGAPPLQLPRV	FOXK2	126	Q01167
PPPQAALTRALRRLQ	INHBE	66	P58166
ARLNPQVRPAVLPTR	KLK15	116	Q9H2R5
RAPRGQIPLLTAARP	LRP3	616	O75074
QRRRLIPAPLPDTTA	KIF26A	1706	Q9ULI4
ARKIPAPFRPQIRSE	RPS6KA4	311	O75676
GRRNLQPRPSAFKPL	POM121L12	206	Q8N7R1
NPLAPEFIPRALRLQ	HELZ	1101	P42694
LAVRASPRPLARPQS	KCTD17	281	Q8N5Z5
LPPTDARFRPDQRFL	OSBPL6	846	Q9BZF3
ETPNARAQRLARPPL	DXO	166	O77932
SPERFLPLNIRNSPF	RBBP6	861	Q7Z6E9
RAPQPVFREPLQSLQ	OBSCN	3886	Q5VST9
RTRPPLLISLPQDFR	PARD6A	126	Q9NPB6
VPSAPRRFRVRQPNL	NFASC	931	O94856
ARPRVRPLLTFLPLN	C6orf132	71	Q5T0Z8
PFLPQASRLQAKRDP	GNPTG	41	Q9UJJ9
QRNSTELAPPLPVRR	DOCK5	1831	Q9H7D0
LAAFLQQLRSPRQPP	CYP24A1	11	Q07973
RPSQLAPATLRAPQR	GFY	361	I3L273
PVNFLPVPSRTRINN	DHX57	436	Q6P158
DNPSFPNPRRRLRLQ	ADCY3	556	O60266
APDFRLNPVRRLIPA	CNTN2	416	Q02246
ARVSRPAEKPIQRNP	COL27A1	416	Q8IZC6
PQVQIPFPRRSRRLS	MIDEAS	336	Q6PJG2
LKRRRLPLPVQNAPS	FOXM1	11	Q08050
RLPRQARLSPAVQPL	KLK9	116	Q9UKQ9
RLQLFPRSCSPPRRF	KPRP	261	Q5T749
RRFRSVPRNLPATDP	ECM1	316	Q16610
IFRIPSLVPRLSPQN	DNAH9	956	Q9NYC9
AQPQPCRRGFIPNIR	FBN2	256	P35556
FLRRQEKQPSAPPAR	CCDC8	156	Q9H0W5
EKQPSAPPARRRVNL	CCDC8	161	Q9H0W5
FPNRLPLLSNIRPDF	CA5BP1	156	Q8WTZ4
RIPQLSVLCAQPRPR	NIT1	21	Q86X76
FLPRPRPSANRQRLD	MAP3K9	991	P80192
PRRKSNLPIFLPRVA	MLPH	506	Q9BV36
DVPPSPSQVARLNRL	PARD3	1331	Q8TEW0
LARCPPPRSQRTQGF	ITPRIPL2	516	Q3MIP1
NFVIRRNPADPQRIP	EFEMP1	136	Q12805
LLPARQAPTRPRARS	SYDE1	561	Q6ZW31
PPPRDFLLDIARQRN	TAF9	86	Q16594
GLEVPCRPPNRFQRL	HSF5	141	Q4G112
APSFRPQNLRLLHPQ	DROSHA	31	Q9NRR4
LQRDFSPRVPLPRLD	PLEKHH3	546	Q7Z736
LVRLRQSPRAFIPPA	SPON2	241	Q9BUD6
RQPRNEKPPRFQRDS	TDRD3	326	Q9H7E2
LPSIPISRQEPRFAR	TOGARAM2	436	Q6ZUX3
PVLTQARRRRQAPAP	MMP17	116	Q9ULZ9
PAPPTRLFQVRRNLA	SCIN	506	Q9Y6U3
RNSISRFNSLPRPDP	PLEKHG3	751	A1L390
KPSRPPIVNLQAFQR	FYB2	281	Q5VWT5
LRNVQRPLLQAPFLP	RHOBTB2	221	Q9BYZ6
RLFDQQLSPGLRPRP	INPP5D	236	Q92835
CFTRVQPTPLRQPRL	SELENOO	81	Q9BVL4
RCRSPLNPFLLTVPR	SHOC1	316	Q5VXU9
LSLEPVLPARNPNRF	SHROOM4	311	Q9ULL8
ARPQLLAPETALRPN	SAMD11	371	Q96NU1
RFIPFLNPRTPRKLT	NLRP7	156	Q8WX94
QLFPLESIRQPRLFP	OPRPN	86	Q99935
LNNPLPRERTPFALQ	TICAM2	176	Q86XR7
QPAFQALPAPEIRRS	SPATA3	66	Q8NHX4
QAVARRPRDLPAIQP	PLPBP	26	O94903
APRQPRLRVLFDPES	PROB1	896	E7EW31
TVLADLPPPRRLAQR	TRIOBP	1271	Q9H2D6
LQFRPDLRLLQPPTA	SOX30	101	O94993
LRPIARPNPGFLRQL	SSH3	446	Q8TE77
RRSFPPRTNPDKIAQ	PLEKHA6	296	Q9Y2H5
RAFPSPLQRQSASPR	ZNF343	191	Q6P1L6
PSPARPRLLQDTVQR	TEP1	1141	Q99973
PLLRENPRRFVIFPI	RRM2	71	P31350
QLATARPRPVKARPL	TSEN34	186	Q9BSV6
PPSRPRNELNVFNRL	KIF21A	1276	Q7Z4S6
ALRPRPGRPTALFQL	SH2D3A	66	Q9BRG2
PSPPRLRLSFQELQA	SEMA3B	26	Q13214
PAPLSPQQAFRRRAN	TBC1D1	581	Q86TI0
QLAPREKLPLSNRRP	USP17L21	61	D6R901
PQLRLEPRVPFRQFQ	PRRC2B	306	Q5JSZ5
RPLPRSTFARPAFNL	TENM4	316	Q6N022
PLPRLANQDSRPVFT	SEZ6	106	Q53EL9
PRFNARKLQEATRPP	PRR33	291	A8MZF0
RTLGAFSRPPQRQPV	ZNF133	161	P52736
QLAPREKLPLSNRRP	USP17L12	61	C9JPN9
PVPSLQPRARFQRCS	UTS2R	341	Q9UKP6
LRPVAFARAPRLPIT	ZNF526	551	Q8TF50
PRRLQASPFRLVPNV	SH3RF2	106	Q8TEC5
PAPFLNRLVRPRRSA	TNFSF12	81	O43508
NPLDPPLRSRFQARD	VWA8	251	A3KMH1
IPLLLPPRNIFNNRL	UBR2	1221	Q8IWV8
PPSRRRPFFSLQQIE	ZNF335	716	Q9H4Z2
LDANRPVPFRLTPNI	TRRAP	3721	Q9Y4A5
LFPTTKIPNPRFQRL	XRCC5	476	P13010
NARVVRVAPLRPGFA	nan	86	Q8N402
PRVRALQLPYRCAQP	KLK10	151	O43240
SNRPPIRAEGRNFPL	LCP2	386	Q13094
SNRLQKLPPDPIFAR	LRFN2	206	Q9ULH4