Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	1-phosphatidylinositol-3-kinase activity	PIK3CA PIK3CB ATM	2.74e-05	11	112	3	GO:0016303
GeneOntologyMolecularFunction	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity	B4GALNT4 B4GALNT3	3.12e-05	2	112	2	GO:0033842
GeneOntologyMolecularFunction	DNA-dependent protein kinase activity	PRKDC ATM	9.32e-05	3	112	2	GO:0004677
GeneOntologyMolecularFunction	histone H2AXS139 kinase activity	PRKDC ATM	9.32e-05	3	112	2	GO:0035979
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DNAH1 DNAH5	1.32e-04	18	112	3	GO:0008569
GeneOntologyMolecularFunction	histone H2AX kinase activity	PRKDC ATM	3.08e-04	5	112	2	GO:0141003
GeneOntologyMolecularFunction	phosphatidylinositol kinase activity	PIK3CA PIK3CB ATM	4.07e-04	26	112	3	GO:0052742
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNHD1 DNAH1 DNAH5	5.08e-04	28	112	3	GO:0051959
GeneOntologyMolecularFunction	protein kinase activity	SMG1 FLT1 ACVR2A NEK4 PIK3CA PIK3CB PRKDC ATM MERTK PLK4 ALPK2	5.56e-04	600	112	11	GO:0004672
GeneOntologyMolecularFunction	1-phosphatidylinositol-4-phosphate 3-kinase activity	PIK3CA PIK3CB	6.43e-04	7	112	2	GO:0035005
GeneOntologyMolecularFunction	1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity	PIK3CA PIK3CB	6.43e-04	7	112	2	GO:0046934
GeneOntologyMolecularFunction	microtubule motor activity	DNHD1 DNAH1 DNAH5 KIF1C	6.47e-04	70	112	4	GO:0003777
GeneOntologyMolecularFunction	nucleocytoplasmic carrier activity	XPO1 IPO9 IPO11	7.57e-04	32	112	3	GO:0140142
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	SMG1 ACVR2A NEK4 PIK3CA PIK3CB PRKDC ATM PLK4 ALPK2	9.22e-04	446	112	9	GO:0004674
GeneOntologyMolecularFunction	protein serine kinase activity	SMG1 NEK4 PIK3CA PIK3CB PRKDC ATM PLK4 ALPK2	1.02e-03	363	112	8	GO:0106310
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNHD1 DNAH1 DNAH5	1.16e-03	37	112	3	GO:0045505
GeneOntologyMolecularFunction	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	CPS1 QRSL1	1.36e-03	10	112	2	GO:0016884
GeneOntologyMolecularFunction	lipopeptide binding	CD1D TLR2	1.36e-03	10	112	2	GO:0071723
GeneOntologyMolecularFunction	lipid kinase activity	PIK3CA PIK3CB ATM	1.57e-03	41	112	3	GO:0001727
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	SMG1 FLT1 ACVR2A NEK4 PIK3CA PIK3CB PRKDC ATM MERTK PLK4 ALPK2	2.13e-03	709	112	11	GO:0016773
Domain	PI3/4_kinase_CS	SMG1 PIK3CA PIK3CB PRKDC ATM	1.69e-08	15	108	5	IPR018936
Domain	-	SMG1 PIK3CA PIK3CB PRKDC ATM	2.45e-08	16	108	5	1.10.1070.11
Domain	PI3Kc	SMG1 PIK3CA PIK3CB PRKDC ATM	2.45e-08	16	108	5	SM00146
Domain	PI3_PI4_kinase	SMG1 PIK3CA PIK3CB PRKDC ATM	4.75e-08	18	108	5	PF00454
Domain	PI3_4_KINASE_1	SMG1 PIK3CA PIK3CB PRKDC ATM	4.75e-08	18	108	5	PS00915
Domain	PI3_4_KINASE_2	SMG1 PIK3CA PIK3CB PRKDC ATM	4.75e-08	18	108	5	PS00916
Domain	PI3/4_kinase_cat_dom	SMG1 PIK3CA PIK3CB PRKDC ATM	4.75e-08	18	108	5	IPR000403
Domain	PI3_4_KINASE_3	SMG1 PIK3CA PIK3CB PRKDC ATM	4.75e-08	18	108	5	PS50290
Domain	FATC	SMG1 PRKDC ATM	1.86e-06	5	108	3	PF02260
Domain	-	CPNE8 RAB11FIP2 MYOF C2CD3 PIK3CA PIK3CB PLCG1 CPNE7	2.32e-06	148	108	8	2.60.40.150
Domain	FAT	SMG1 PRKDC ATM	3.71e-06	6	108	3	PS51189
Domain	FATC	SMG1 PRKDC ATM	3.71e-06	6	108	3	PS51190
Domain	FATC_dom	SMG1 PRKDC ATM	3.71e-06	6	108	3	IPR003152
Domain	PIK_FAT	SMG1 PRKDC ATM	3.71e-06	6	108	3	IPR014009
Domain	FATC	SMG1 PRKDC ATM	3.71e-06	6	108	3	SM01343
Domain	ARM-type_fold	SMG1 APOB XPO1 FMNL2 IPO9 AP2A2 PIK3CA PIK3CB PRKDC ATM IPO11	4.31e-06	339	108	11	IPR016024
Domain	C2_dom	CPNE8 RAB11FIP2 MYOF C2CD3 PIK3CA PIK3CB PLCG1 CPNE7	4.98e-06	164	108	8	IPR000008
Domain	C2	CPNE8 RAB11FIP2 MYOF C2CD3 PIK3CA PLCG1 CPNE7	1.47e-05	137	108	7	SM00239
Domain	C2	CPNE8 RAB11FIP2 MYOF C2CD3 PIK3CA PLCG1 CPNE7	1.86e-05	142	108	7	PS50004
Domain	ATM/Tel1	SMG1 ATM	3.31e-05	2	108	2	IPR015519
Domain	Dynein_HC_stalk	DNHD1 DNAH1 DNAH5	6.53e-05	14	108	3	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH1 DNAH5	6.53e-05	14	108	3	IPR013602
Domain	DHC_N2	DNHD1 DNAH1 DNAH5	6.53e-05	14	108	3	PF08393
Domain	IMPORTIN_B_NT	XPO1 IPO9 IPO11	6.53e-05	14	108	3	PS50166
Domain	MT	DNHD1 DNAH1 DNAH5	6.53e-05	14	108	3	PF12777
Domain	DHC_fam	DNHD1 DNAH1 DNAH5	8.13e-05	15	108	3	IPR026983
Domain	Dynein_heavy	DNHD1 DNAH1 DNAH5	8.13e-05	15	108	3	PF03028
Domain	IBN_N	XPO1 IPO9 IPO11	8.13e-05	15	108	3	PF03810
Domain	Dynein_heavy_dom	DNHD1 DNAH1 DNAH5	8.13e-05	15	108	3	IPR004273
Domain	-	B4GALNT4 B4GALNT3	9.90e-05	3	108	2	3.90.182.10
Domain	PA14	B4GALNT4 B4GALNT3	9.90e-05	3	108	2	SM00758
Domain	PA14	B4GALNT4 B4GALNT3	9.90e-05	3	108	2	PF07691
Domain	PA14_dom	B4GALNT4 B4GALNT3	9.90e-05	3	108	2	IPR011658
Domain	PI3K_p85B	PIK3CA PIK3CB	9.90e-05	3	108	2	PF02192
Domain	PI3K_p85B	PIK3CA PIK3CB	9.90e-05	3	108	2	SM00143
Domain	IBN_N	XPO1 IPO9 IPO11	9.97e-05	16	108	3	SM00913
Domain	C2	CPNE8 RAB11FIP2 MYOF C2CD3 PLCG1 CPNE7	1.13e-04	131	108	6	PF00168
Domain	Importin-beta_N	XPO1 IPO9 IPO11	1.21e-04	17	108	3	IPR001494
Domain	DysFC	MYOF TECPR1	1.97e-04	4	108	2	SM00694
Domain	DysFN	MYOF TECPR1	1.97e-04	4	108	2	SM00693
Domain	PI3K_ABD	PIK3CA PIK3CB	1.97e-04	4	108	2	PS51544
Domain	PI3K_adapt-bd_dom	PIK3CA PIK3CB	1.97e-04	4	108	2	IPR003113
Domain	Peroxin/Ferlin	MYOF TECPR1	1.97e-04	4	108	2	IPR006614
Domain	Kinase-like_dom	SMG1 FLT1 ACVR2A NEK4 PIK3CA PIK3CB PRKDC ATM MERTK PLK4 ALPK2	3.02e-04	542	108	11	IPR011009
Domain	YTH	YTHDF1 YTHDF3	3.28e-04	5	108	2	PF04146
Domain	YTH_domain	YTHDF1 YTHDF3	3.28e-04	5	108	2	IPR007275
Domain	CPSASE_1	ACACA CPS1	3.28e-04	5	108	2	PS00866
Domain	YTH	YTHDF1 YTHDF3	3.28e-04	5	108	2	PS50882
Domain	CPSASE_2	ACACA CPS1	4.89e-04	6	108	2	PS00867
Domain	FAT	PRKDC ATM	4.89e-04	6	108	2	PF02259
Domain	PIK-rel_kinase_FAT	PRKDC ATM	4.89e-04	6	108	2	IPR003151
Domain	PI3K_Ras-bd_dom	PIK3CA PIK3CB	6.83e-04	7	108	2	IPR000341
Domain	CbamoylP_synth_lsu-like_ATP-bd	ACACA CPS1	6.83e-04	7	108	2	IPR005479
Domain	BC-like_N	ACACA CPS1	6.83e-04	7	108	2	IPR005481
Domain	PI3K_rbd	PIK3CA PIK3CB	6.83e-04	7	108	2	SM00144
Domain	CPSase_L_D2	ACACA CPS1	6.83e-04	7	108	2	PF02786
Domain	PI3K_rbd	PIK3CA PIK3CB	6.83e-04	7	108	2	PF00794
Domain	PI3K_RBD	PIK3CA PIK3CB	6.83e-04	7	108	2	PS51546
Domain	Biotin_carb_N	ACACA CPS1	6.83e-04	7	108	2	PF00289
Domain	HEAT_REPEAT	SMG1 XPO1 PRKDC IPO11	7.23e-04	70	108	4	PS50077
Domain	Chond_GalNAc	B4GALNT4 B4GALNT3	9.07e-04	8	108	2	IPR008428
Domain	PI3K_C2	PIK3CA PIK3CB	9.07e-04	8	108	2	SM00142
Domain	CHGN	B4GALNT4 B4GALNT3	9.07e-04	8	108	2	PF05679
Domain	PI3K_C2_dom	PIK3CA PIK3CB	9.07e-04	8	108	2	IPR002420
Domain	PI3K_C2	PIK3CA PIK3CB	9.07e-04	8	108	2	PF00792
Domain	PI3K_C2	PIK3CA PIK3CB	9.07e-04	8	108	2	PS51547
Domain	IGv	FLT1 VSIG4 BTN3A2 BTN3A1	9.37e-04	75	108	4	SM00406
Domain	Copine	CPNE8 CPNE7	1.16e-03	9	108	2	PF07002
Domain	PI3Ka	PIK3CA PIK3CB	1.16e-03	9	108	2	PF00613
Domain	PI3Ka	PIK3CA PIK3CB	1.16e-03	9	108	2	SM00145
Domain	Copine	CPNE8 CPNE7	1.16e-03	9	108	2	IPR010734
Domain	-	PIK3CA PIK3CB	1.16e-03	9	108	2	1.25.40.70
Domain	VWFA	CPNE8 ITGA2 VWA3B CPNE7	1.31e-03	82	108	4	PS50234
Domain	VWA	CPNE8 ITGA2 VWA3B CPNE7	1.43e-03	84	108	4	SM00327
Domain	PI_Kinase	PIK3CA PIK3CB	1.45e-03	10	108	2	IPR015433
Domain	PInositide-3_kin_accessory_dom	PIK3CA PIK3CB	1.45e-03	10	108	2	IPR001263
Domain	PIK_HELICAL	PIK3CA PIK3CB	1.45e-03	10	108	2	PS51545
Domain	-	ACACA CPS1	2.48e-03	13	108	2	3.40.50.20
Domain	VWF_A	CPNE8 ITGA2 VWA3B CPNE7	2.61e-03	99	108	4	IPR002035
Domain	Dynein_heavy_chain_D4_dom	DNAH1 DNAH5	2.88e-03	14	108	2	IPR024317
Domain	ATPase_dyneun-rel_AAA	DNAH1 DNAH5	2.88e-03	14	108	2	IPR011704
Domain	ATP_GRASP	ACACA CPS1	2.88e-03	14	108	2	PS50975
Domain	ATP-grasp	ACACA CPS1	2.88e-03	14	108	2	IPR011761
Domain	PreATP-grasp_dom	ACACA CPS1	2.88e-03	14	108	2	IPR016185
Domain	AAA_8	DNAH1 DNAH5	2.88e-03	14	108	2	PF12780
Domain	AAA_5	DNAH1 DNAH5	2.88e-03	14	108	2	PF07728
Domain	-	ACACA CPS1	3.31e-03	15	108	2	3.30.1490.20
Domain	HEAT	XPO1 PRKDC IPO11	4.61e-03	58	108	3	IPR000357
Domain	ATP_grasp_subdomain_1	ACACA CPS1	4.77e-03	18	108	2	IPR013815
Domain	-	ACACA CPS1	4.77e-03	18	108	2	3.30.470.20
Domain	ARM-like	SMG1 XPO1 IPO9 AP2A2 PRKDC IPO11	4.84e-03	270	108	6	IPR011989
Pathway	KEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY	PGR PIK3CA PIK3CB	1.33e-05	8	89	3	M47803
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	HEXA HSPH1 PSMD3 XPO1 CPS1 MYOF IPO9 AP2A2 PA2G4 PLCG1 PRKDC IPO11 TECPR1	1.09e-10	344	113	13	30333137
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	NCOA6 ACACA HSPH1 PSMD3 TFIP11 PRPF6 XPO1 RFX7 DNAH1 RHOQ MYOF IPO9 AP2A2 PIK3CA PA2G4 PRMT5 PRKDC YTHDF3	1.14e-07	1247	113	18	27684187
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	SMG1 CPNE8 HSPH1 PSMD3 PRPF6 XPO1 HIRA MYOF AFAP1 IPO9 AP2A2 PA2G4 PRMT5 PRKDC ATM ATP5PD COG4 ILVBL IPO11	1.95e-07	1440	113	19	30833792
Pubmed	Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase.	PIK3CA PIK3CB PRKDC	3.32e-07	5	113	3	15664519
Pubmed	Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.	HSPH1 PSMD3 PRPF6 XPO1 GTF3C3 IPO9 PRKDC ILVBL	4.76e-07	211	113	8	17314511
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DNHD1 ACACA HSPH1 PSMD3 APOB PRPF6 XPO1 GTF3C3 MFGE8 IPO9 AP2A2 PA2G4 PRMT5 PLCG1 PRKDC ATM TDRD6 DNAH5	7.99e-07	1425	113	18	30948266
Pubmed	Human transcription factor protein interaction networks.	UIMC1 SMG1 NCOA6 VEZF1 SCAF8 HSPH1 IRF1 PSMD3 TFIP11 RFX7 GTF3C3 HIRA YTHDF1 TNRC6A LRP2 ATP5PD ILVBL YTHDF3	8.32e-07	1429	113	18	35140242
Pubmed	Substrate specificities and identification of putative substrates of ATM kinase family members.	PIK3CA PA2G4 PRKDC ATM	1.27e-06	25	113	4	10608806
Pubmed	A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.	SMG1 PRKDC ATM	1.85e-06	8	113	3	20810650
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	CA12 HSPH1 TCIRG1 APOB EXT1 ACVR2A MYOF SETD2 INTS5 SCARA5 PACC1 PRKDC ATM ATP5PD IPO11	1.86e-06	1061	113	15	33845483
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	STXBP4 RAB11FIP2 RSU1 NEK4 AP2A2 TNRC6A PRKDC ILVBL IPO11 KIF1C	2.08e-06	446	113	10	24255178
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	XPO1 IPO9 AP2A2 PIK3CB PRKDC COG4 IPO11	2.40e-06	183	113	7	23956138
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	HSPH1 TFIP11 YTHDF1 AP2A2 PRMT5 TDRD6 YTHDF3	3.91e-06	197	113	7	20811636
Pubmed	Tel2 regulates the stability of PI3K-related protein kinases.	SMG1 PRKDC ATM	3.94e-06	10	113	3	18160036
Pubmed	Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.	SMG1 PRKDC ATM	5.41e-06	11	113	3	20427287
Pubmed	Ligands of CD4 inhibit the association of phospholipase Cgamma1 with phosphoinositide 3 kinase in T cells: regulation of this association by the phosphoinositide 3 kinase activity.	PIK3CA PIK3CB PLCG1	5.41e-06	11	113	3	9808187
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	UIMC1 NCOA6 ACACA SCAF8 TFIP11 XPO1 RFX7 MYOF SETD2 INTS5 PRKDC ATM	8.61e-06	774	113	12	15302935
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	CPNE8 VEZF1 HSPH1 TFIP11 APOB PRPF6 FMNL2 RSU1 GTF3C3 YTHDF1 IPO9 AP2A2 PA2G4 TNRC6A YTHDF3 CPNE7	9.43e-06	1371	113	16	36244648
Pubmed	Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.	HSPH1 TCIRG1 PRPF6 XPO1 CPS1 MYOF PRMT5 PYGB PRKDC	1.03e-05	422	113	9	27342126
Pubmed	Phosphoinositide 3-kinases p110alpha and p110beta regulate cell cycle entry, exhibiting distinct activation kinetics in G1 phase.	PIK3CA PIK3CB	1.05e-05	2	113	2	18285463
Pubmed	Synthetic lethality between mutation in Atm and DNA-PK(cs) during murine embryogenesis.	PRKDC ATM	1.05e-05	2	113	2	11231155
Pubmed	Deletion of YTHDF1 (not YTHDF3) reduced brain and gut damage after traumatic brain injury.	YTHDF1 YTHDF3	1.05e-05	2	113	2	39081030
Pubmed	Distinct roles for isoforms of the catalytic subunit of class-IA PI3K in the regulation of behaviour of murine embryonic stem cells.	PIK3CA PIK3CB	1.05e-05	2	113	2	19509054
Pubmed	Phosphatidylinositol 3-kinase interacts with the glucocorticoid receptor upon TLR2 activation.	PIK3CA TLR2	1.05e-05	2	113	2	19874421
Pubmed	The p110α and p110β isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis.	PIK3CA PIK3CB	1.05e-05	2	113	2	22802530
Pubmed	PIP3 abundance overcomes PI3K signaling selectivity in invadopodia.	PIK3CA PIK3CB	1.05e-05	2	113	2	34990021
Pubmed	Combined Inhibition of Both p110α and p110β Isoforms of Phosphatidylinositol 3-Kinase Is Required for Sustained Therapeutic Effect in PTEN-Deficient, ER+ Breast Cancer.	PIK3CA PIK3CB	1.05e-05	2	113	2	27903677
Pubmed	SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress.	SMG1 ATM	1.05e-05	2	113	2	31565865
Pubmed	The phosphatidylinositol 3-kinase (PI3K) isoform dependence of tumor formation is determined by the genetic mode of PI3K pathway activation rather than by tissue type.	PIK3CA PIK3CB	1.05e-05	2	113	2	24991009
Pubmed	Distinct and opposing roles for the phosphatidylinositol 3-OH kinase catalytic subunits p110α and p110β in the regulation of insulin secretion from rodent and human beta cells.	PIK3CA PIK3CB	1.05e-05	2	113	2	23568272
Pubmed	Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation.	PRKDC ATM	1.05e-05	2	113	2	10464290
Pubmed	Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.	PRKDC ATM	1.05e-05	2	113	2	27939942
Pubmed	The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA.	PRKDC ATM	1.05e-05	2	113	2	21487018
Pubmed	TDRD6 mediates early steps of spliceosome maturation in primary spermatocytes.	PRMT5 TDRD6	1.05e-05	2	113	2	28263986
Pubmed	Activation of DNA Damage Response Pathways during Lytic Replication of KSHV.	PRKDC ATM	1.05e-05	2	113	2	26057167
Pubmed	hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress.	SMG1 ATM	1.05e-05	2	113	2	18332866
Pubmed	Ablation of PI3K p110-α prevents high-fat diet-induced liver steatosis.	PIK3CA PIK3CB	1.05e-05	2	113	2	21464441
Pubmed	Phosphoinositide 3-kinases p110α and p110β have differential roles in insulin-like growth factor-1-mediated Akt phosphorylation and platelet priming.	PIK3CA PIK3CB	1.05e-05	2	113	2	24903091
Pubmed	Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor.	PIK3CA PIK3CB	1.05e-05	2	113	2	22150431
Pubmed	Differential Expression of VEGFA Isoforms Regulates Metastasis and Response to Anti-VEGFA Therapy in Sarcoma.	FLT1 PRKDC	1.05e-05	2	113	2	28377452
Pubmed	Inflammatory bone loss associated with MFG-E8 deficiency is rescued by teriparatide.	MFGE8 MERTK	1.05e-05	2	113	2	29475373
Pubmed	PI3K Catalytic Subunits α and β Modulate Cell Death and IL-6 Secretion Induced by Talc Particles in Human Lung Carcinoma Cells.	PIK3CA PIK3CB	1.05e-05	2	113	2	31513749
Pubmed	The Phosphoinosotide 3-Kinase Catalytic Subunit p110α is Required for Normal Lens Growth.	PIK3CA PIK3CB	1.05e-05	2	113	2	27304846
Pubmed	DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases.	PRKDC ATM	1.05e-05	2	113	2	19071136
Pubmed	Roles of DNA-dependent protein kinase and ATM in cell-cycle-dependent radiation sensitivity in human cells.	PRKDC ATM	1.05e-05	2	113	2	12065055
Pubmed	Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI 3-kinase.	PIK3CA PIK3CB	1.05e-05	2	113	2	11919689
Pubmed	Truncated apo B-70.5-containing lipoproteins bind to megalin but not the LDL receptor.	APOB LRP2	1.05e-05	2	113	2	10330424
Pubmed	Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis.	PIK3CA PIK3CB	1.05e-05	2	113	2	23051731
Pubmed	PIK3CA and PIK3CB silencing by RNAi reverse MDR and inhibit tumorigenic properties in human colorectal carcinoma.	PIK3CA PIK3CB	1.05e-05	2	113	2	26747178
Pubmed	Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.	PRKDC ATM	1.05e-05	2	113	2	17189255
Pubmed	AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation.	PRKDC ATM	1.05e-05	2	113	2	22972376
Pubmed	G(2)-M phase-correlative bystander effects are co-mediated by DNA-PKcs and ATM after carbon ion irradiation.	PRKDC ATM	1.05e-05	2	113	2	26774662
Pubmed	Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells.	XPO1 YTHDF1	1.05e-05	2	113	2	33526437
Pubmed	CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease.	VSIG4 TLR2	1.05e-05	2	113	2	34887405
Pubmed	Distinct epithelial-to-mesenchymal transitions induced by PIK3CAH1047R and PIK3CB.	PIK3CA PIK3CB	1.05e-05	2	113	2	33526718
Pubmed	p110α and p110β isoforms of PI3K are involved in protection against H2O2 induced oxidative stress in cancer cells.	PIK3CA PIK3CB	1.05e-05	2	113	2	30499025
Pubmed	Phosphatidylinositol 3-kinase mediates activation of ATM by high NaCl and by ionizing radiation: Role in osmoprotective transcriptional regulation.	PIK3CA ATM	1.05e-05	2	113	2	16728507
Pubmed	Expression of PI3Kp110α and PI3Kp110β in the colorectal conventional adenoma, serrated lesions and adenoma with canceration and their significance.	PIK3CA PIK3CB	1.05e-05	2	113	2	26884879
Pubmed	DNA-PKcs and ATM modulate mitochondrial ADP-ATP exchange as an oxidative stress checkpoint mechanism.	PRKDC ATM	1.05e-05	2	113	2	36727301
Pubmed	Cytoplasmic m6A reader YTHDF3 promotes mRNA translation.	YTHDF1 YTHDF3	1.05e-05	2	113	2	28106076
Pubmed	The phosphorylated 1169-tyrosine containing region of flt-1 kinase (VEGFR-1) is a major binding site for PLCgamma.	FLT1 PLCG1	1.05e-05	2	113	2	9299537
Pubmed	Differential role for CD277 as a co-regulator of the immune signal in T and NK cells.	BTN3A2 BTN3A1	1.05e-05	2	113	2	21918970
Pubmed	The molecular basis for modulation of human Vγ9Vδ2 T cell responses by CD277/butyrophilin-3 (BTN3A)-specific antibodies.	BTN3A2 BTN3A1	1.05e-05	2	113	2	22846996
Pubmed	The class IA phosphatidylinositol 3-kinase p110-beta subunit is a positive regulator of autophagy.	PIK3CA PIK3CB	1.05e-05	2	113	2	21059846
Pubmed	Phagocytosis executes delayed neuronal death after focal brain ischemia.	MFGE8 MERTK	1.05e-05	2	113	2	24101459
Pubmed	Role of p110a subunit of PI3-kinase in skeletal muscle mitochondrial homeostasis and metabolism.	PIK3CA PIK3CB	1.05e-05	2	113	2	31363081
Pubmed	A necessary and sufficient determinant for protein-selective glycosylation in vivo.	B4GALNT4 B4GALNT3	1.05e-05	2	113	2	18048353
Pubmed	The acute effects of leptin require PI3K signaling in the hypothalamic ventral premammillary nucleus.	PIK3CA PIK3CB	1.05e-05	2	113	2	21917798
Pubmed	The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cells.	PIK3CA PIK3CB	1.05e-05	2	113	2	16339315
Pubmed	Deciphering the role of distinct DNA-PK phosphorylations at collapsed replication forks.	PRKDC ATM	1.05e-05	2	113	2	32674014
Pubmed	Mutation analysis of PIK3CA and PIK3CB in esophageal cancer and Barrett's esophagus.	PIK3CA PIK3CB	1.05e-05	2	113	2	16380997
Pubmed	PIK3CA and PIK3CB expression and relationship with multidrug resistance in colorectal carcinoma.	PIK3CA PIK3CB	1.05e-05	2	113	2	25550888
Pubmed	Molecular basis for protein-specific transfer of N-acetylgalactosamine to N-linked glycans by the glycosyltransferases β1,4-N-acetylgalactosaminyl transferase 3 (β4GalNAc-T3) and β4GalNAc-T4.	B4GALNT4 B4GALNT3	1.05e-05	2	113	2	22722937
Pubmed	Peptide-specific transfer of N-acetylgalactosamine to O-linked glycans by the glycosyltransferases β1,4-N-acetylgalactosaminyl transferase 3 (β4GalNAc-T3) and β4GalNAc-T4.	B4GALNT4 B4GALNT3	1.05e-05	2	113	2	22722940
Pubmed	Ataxia telangiectasia-mutated protein and DNA-dependent protein kinase have complementary V(D)J recombination functions.	PRKDC ATM	1.05e-05	2	113	2	21245310
Pubmed	PI3K p110 alpha and p110 beta have differential effects on Akt activation and protection against oxidative stress-induced apoptosis in myoblasts.	PIK3CA PIK3CB	1.05e-05	2	113	2	19834495
Pubmed	The molecular causes of low ATM protein expression in breast carcinoma; promoter methylation and levels of the catalytic subunit of DNA-dependent protein kinase.	PRKDC ATM	1.05e-05	2	113	2	17593081
Pubmed	The gene dosage of class Ia PI3K dictates the development of PTEN hamartoma tumor syndrome.	PIK3CA PIK3CB	1.05e-05	2	113	2	24131925
Pubmed	CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells.	BTN3A2 BTN3A1	1.05e-05	2	113	2	21113407
Pubmed	Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation.	PRKDC ATM	1.05e-05	2	113	2	20617180
Pubmed	Expression of Phosphoinositide 3-Kinase p110α and p110β Subunits and PIK3CA Mutation in Patients With Advanced Gastric Carcinoma.	PIK3CA PIK3CB	1.05e-05	2	113	2	28549032
Pubmed	Nuclear receptor coactivator-6 attenuates uterine estrogen sensitivity to permit embryo implantation.	NCOA6 PGR	1.05e-05	2	113	2	23079602
Pubmed	The PI3K inhibitor GDC-0941 combines with existing clinical regimens for superior activity in multiple myeloma.	PIK3CA PIK3CB	1.05e-05	2	113	2	23318440
Pubmed	DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells.	PRKDC ATM	1.05e-05	2	113	2	18172300
Pubmed	Signaling properties of VEGF receptor-1 and -2 homo- and heterodimers.	FLT1 PLCG1	1.05e-05	2	113	2	11312102
Pubmed	Profiling of phosphoinositide molecular species in human and mouse platelets identifies new species increasing following stimulation.	PIK3CA PIK3CB	1.05e-05	2	113	2	29902570
Pubmed	B-1a cell diversity: nontemplated addition in B-1a cell Ig is determined by progenitor population and developmental location.	PRKDC DNTT	1.05e-05	2	113	2	24477911
Pubmed	Adipose tissue insulin resistance due to loss of PI3K p110α leads to decreased energy expenditure and obesity.	PIK3CA PIK3CB	1.05e-05	2	113	2	24691033
Pubmed	Phosphoinositide 3-kinase catalytic subunit deletion and regulatory subunit deletion have opposite effects on insulin sensitivity in mice.	PIK3CA PIK3CB	1.05e-05	2	113	2	15713620
Pubmed	Pik3ca is required for mouse uterine gland development and pregnancy.	PGR PIK3CA	1.05e-05	2	113	2	29346447
Pubmed	Chemokine coreceptor signaling in HIV-1 infection and pathogenesis.	PIK3CA PIK3CB PLCG1	1.18e-05	14	113	3	20041213
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	ACACA SCAF8 HSPH1 PSMD3 TFIP11 PRPF6 XPO1 CPS1 RSU1 AP2A2 PA2G4 PRMT5 PRKDC ATP5PD YTHDF3 KIF1C	1.39e-05	1415	113	16	28515276
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	CPNE8 HSPH1 PSMD3 XPO1 YTHDF1 AP2A2 PA2G4 PYGB PRKDC IL36G YTHDF3 CPNE7	2.03e-05	844	113	12	25963833
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NCOA6 ACACA STXBP4 RAB11FIP2 RFX7 NEK4 PTOV1 C2CD3 IPO9 PRMT5 PLK4 KIF1C	2.46e-05	861	113	12	36931259
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	ACACA VEZF1 HSPH1 EXT1 MAU2 XPO1 AZIN1 MFGE8 SETD2 IPO9 PIK3CA PIK3CB KICS2 PLCG1 CPNE7	2.66e-05	1327	113	15	32694731
Pubmed	Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.	SMG1 YTHDF1 TNRC6A PRKDC YTHDF3	2.70e-05	107	113	5	30995489
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	HSPH1 XPO1 CPS1 IPO9 PRMT5 PRKDC	2.74e-05	179	113	6	36261009
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	VEZF1 HSPH1 PSMD3 XPO1 IPO9 AP2A2 PRMT5 PYGB PRKDC QRSL1 COG4 IPO11	2.98e-05	878	113	12	37223481
Pubmed	Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.	AP2A2 PIK3CA PIK3CB	3.12e-05	19	113	3	31959764
Pubmed	Synergistic activation of a family of phosphoinositide 3-kinase via G-protein coupled and tyrosine kinase-related receptors.	PIK3CA PIK3CB	3.13e-05	3	113	2	10358930
Interaction	ITGB3 interactions	HSPH1 XPO1 MYOF IPO9 AP2A2 PRKDC IPO11 TECPR1	4.59e-06	170	111	8	int:ITGB3
Interaction	BTN3A1 interactions	BTN3A2 BTN3A1 PIK3CA PIK3CB	7.12e-06	23	111	4	int:BTN3A1
Interaction	CHRM4 interactions	XPO1 INTS5 IPO9 PRKDC COG4 IPO11	1.34e-05	94	111	6	int:CHRM4
Cytoband	11q22-q23	PGR ATM	8.95e-05	6	113	2	11q22-q23
Cytoband	Ensembl 112 genes in cytogenetic band chr3p21	CACNA1D DNAH1 NEK4 SETD2 ZNF35 PLXNB1	1.38e-04	316	113	6	chr3p21
GeneFamily	Phosphatidylinositol 3-kinase subunits	PIK3CA PIK3CB	4.55e-04	8	74	2	831
GeneFamily	Copines	CPNE8 CPNE7	5.84e-04	9	74	2	829
GeneFamily	Butyrophilins\|V-set domain containing\|C2-set domain containing	BTN3A2 BTN3A1	1.68e-03	15	74	2	458
GeneFamily	Dyneins, axonemal	DNAH1 DNAH5	2.16e-03	17	74	2	536
GeneFamily	Beta 4-glycosyltransferases	B4GALNT4 B4GALNT3	2.16e-03	17	74	2	425
GeneFamily	Armadillo repeat containing\|Importins	IPO9 IPO11	2.42e-03	18	74	2	596
Coexpression	GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_DN	VSIG4 RGL1 SETD2 AP2A2 TLR2 MERTK PLS1 YTHDF3	2.39e-06	198	113	8	M7229
Coexpression	GSE19374_UNINF_VS_LISTERIA_INFECTED_MACROPHAGE_DN	CA12 NCOA6 ACVR2A NEK4 AFAP1 AP2A2 IL36G DNTT	2.39e-06	198	113	8	M7265
Coexpression	GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP	FLT1 ACACA EXT1 FMNL2 HIRA RGL1 MERTK	2.10e-05	193	113	7	M3303
Coexpression	GSE19198_6H_VS_24H_IL21_TREATED_TCELL_DN	VSIG4 RGL1 SETD2 AP2A2 TLR2 MERTK PLS1	2.48e-05	198	113	7	M7228
Coexpression	GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_DN	HEXA VEZF1 VSIG4 PSMD3 CD1D AP2A2 CMAHP	2.56e-05	199	113	7	M5201
Coexpression	GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_UP	CA12 IRF1 ACVR2A RFX7 CD1D INTS5 BRD3OS	2.56e-05	199	113	7	M5615
Coexpression	GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_DN	HEXA VSIG4 RGL1 MYOF CD1D TLR2 MERTK	2.64e-05	200	113	7	M4616
Coexpression	GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_UP	HSPH1 GPR85 XPO1 ACVR2A FMNL2 RGL1 PRMT5	2.64e-05	200	113	7	M8638
Coexpression	GSE17721_0.5H_VS_8H_PAM3CSK4_BMDC_DN	GPR85 AZIN1 MYOF CD1D KICS2 IL36G COG4	2.64e-05	200	113	7	M4111
Coexpression	BROWNE_HCMV_INFECTION_24HR_DN	CA12 EXT1 ITGA2 CPS1 B9D1 ATP5PD	4.01e-05	145	113	6	M14098
Coexpression	AIZARANI_LIVER_C6_KUPFFER_CELLS_2	VSIG4 TCIRG1 FMNL2 RGL1 AP2A2 TLR2 MERTK	6.08e-05	228	113	7	M39110
Coexpression	TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP	VSIG4 EXT1 RHOQ MYOF CD1D TLR2	6.71e-05	159	113	6	M12138
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	VEZF1 SCAF8 EXT1 XPO1 HIRA AZIN1 NEK4 RGL1 MYOF SETD2 C2CD3 AFAP1 YTHDF3	8.31e-05	856	113	13	M4500
Coexpression	MARSON_BOUND_BY_FOXP3_UNSTIMULATED	CA12 VEZF1 TPRN STXBP4 HSPH1 XPO1 BTN3A2 BTN3A1 ZNF35 AP2A2 PRMT5 ATM ATP5PD YTHDF3 CPNE7 DNTT	1.18e-04	1277	113	16	MM1032
Coexpression	PATIL_LIVER_CANCER	ACACA PRPF6 ITGA2 XPO1 ABCC6 GTF3C3 PYGB PACC1 PLCG1 PRKDC PLK4	1.35e-04	660	113	11	M1195
Coexpression	DOUGLAS_BMI1_TARGETS_UP	ACACA TCIRG1 BRD3OS PRMT5 TNRC6A PYGB PACC1 B4GALNT3 IPO11 CPNE7	1.66e-04	563	113	10	M15103
Coexpression	CALVET_IRINOTECAN_SENSITIVE_VS_RESISTANT_UP	FLT1 ATM	1.83e-04	5	113	2	M17456
Coexpression	GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN	RAB11FIP2 IRF1 F8 BTN3A1 ASGR2 CMAHP	2.23e-04	198	113	6	M8977
Coexpression	GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_DN	HEXA UIMC1 ARHGEF10L CD1D AFAP1 ASGR2	2.23e-04	198	113	6	M8750
Coexpression	BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	NCOA6 HSPH1 IRF1 MAU2 ITGA2 ACVR2A BTN3A1 RHOQ RGL1 SETD2 PIK3CA TLR2	2.28e-04	822	113	12	M6782
Coexpression	GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_DN	CACNA1D SMG1 PSMD3 RGL1 C2CD3 DNTT	2.29e-04	199	113	6	M5107
Coexpression	GSE7548_NAIVE_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_UP	NCOA6 PIK3CA LRP2 PYGB PRKDC PLS1	2.29e-04	199	113	6	M6839
Coexpression	GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_6H_DN	VSIG4 XPO1 ACVR2A MYOF PRKDC KIF1C	2.29e-04	199	113	6	M8741
Coexpression	GSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN	HSPH1 PGR RHOQ AP2A2 TNRC6A DNTT	2.29e-04	199	113	6	M6987
Coexpression	GSE40655_FOXO1_KO_VS_WT_NTREG_UP	NCOA6 VEZF1 TCIRG1 HIRA ASGR2 TECPR1	2.35e-04	200	113	6	M9439
Coexpression	GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_3H_DN	UIMC1 ACVR2A PYGB PLCG1 ALPK2 TECPR1	2.35e-04	200	113	6	M6414
Coexpression	GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_DN	HEXA ARHGEF10L PTOV1 RHOQ TLR2 PYGB	2.35e-04	200	113	6	M4628
Coexpression	GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN	UIMC1 VEZF1 PRPF6 MYOF PLCG1 DNTT	2.35e-04	200	113	6	M4667
Coexpression	GSE43863_TH1_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_DN	CPNE8 TCIRG1 CD1D ASGR2 PLCG1 MERTK	2.35e-04	200	113	6	M9757
Coexpression	GSE9960_GRAM_POS_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP	SCAF8 IRF1 PTOV1 RGL1 INTS5 PRKDC	2.35e-04	200	113	6	M7132
Coexpression	GSE3982_DC_VS_TH1_UP	FLT1 ACVR2A MYOF CD1D TLR2 MERTK	2.35e-04	200	113	6	M5481
Coexpression	GSE3982_DC_VS_BASOPHIL_UP	ACVR2A ARHGEF10L MYOF BRD3OS MERTK ILVBL	2.35e-04	200	113	6	M5472
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 APOB CPS1 DNAH1 LRP2 SPAG17 DNAH5	4.57e-07	184	113	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 APOB CPS1 DNAH1 LRP2 SPAG17 DNAH5	4.57e-07	184	113	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 APOB CPS1 DNAH1 LRP2 SPAG17 DNAH5	4.57e-07	184	113	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 ABCA12 DNAH1 SPAG17 DNAH5 PLK4 BTG4	7.24e-07	197	113	7	6e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell	NS-critical-LOC-Myeloid-Macrophage\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CPNE8 VSIG4 FMNL2 ARHGEF10L RGL1 MYOF MERTK	7.24e-07	197	113	7	5fb0696376a5501b7c87e0f2f5e4fff3da2903f2
ToppCell	Transverse-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	DNHD1 SLC26A4 MAU2 FMNL2 ARHGEF10L MYOF ZNF75D	7.74e-07	199	113	7	fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HEXA TCIRG1 MYOF SLC7A2 TLR2 MERTK	7.58e-06	184	113	6	fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCell	Myeloid-B_(Activated_Macrophage)\|World / shred on cell class and cell subclass (v4)	HEXA TCIRG1 MYOF SLC7A2 TLR2 MERTK	8.06e-06	186	113	6	33d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HEXA TCIRG1 MYOF SLC7A2 TLR2 MERTK	8.06e-06	186	113	6	7950e03ea080238c168b9d807e217f459acdfb28
ToppCell	facs-Marrow-KLS-18m-Hematologic-MPP_Fraction_A_+_HSC\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE8 STXBP4 PGR PTOV1 MFGE8 IPO11	9.10e-06	190	113	6	96a9756cad5468a12591021e6d661ed269b5b3d9
ToppCell	Control-Epithelial-Ciliated_cells\|Control / Condition, Lineage and Cell class	CFAP47 SLC7A2 VWA3B SPAG17 DNAH5 PLXNB1	9.38e-06	191	113	6	ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell	Control-Epithelial\|Control / Condition, Lineage and Cell class	CFAP47 SLC7A2 VWA3B SPAG17 DNAH5 PLXNB1	9.38e-06	191	113	6	6228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF10L MYOF SCARA5 CMAHP ALPK2 PLXNB1	9.66e-06	192	113	6	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Myeloid-Macrophages\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VSIG4 RGL1 CD1D AP2A2 TLR2 MERTK	1.02e-05	194	113	6	7c7091de47359760003e910cfbe63db5c99410d6
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|lung / Disease (COVID-19 only), tissue and cell type	VSIG4 FMNL2 ARHGEF10L RGL1 TLR2 MERTK	1.06e-05	195	113	6	148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	CA12 ITGA2 MYOF TLR2 PYGB DNAH5	1.09e-05	196	113	6	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	COVID-19-lung-Macrophage_metabolically_active\|lung / Disease (COVID-19 only), tissue and cell type	VSIG4 FMNL2 ARHGEF10L RGL1 TLR2 MERTK	1.09e-05	196	113	6	a753d76d764c181eecb0e17a794a2e7d0ff70136
ToppCell	VE-mono1-\|VE / Condition, Cell_class and T cell subcluster	VSIG4 ARHGEF10L RGL1 MYOF ASGR2 TLR2	1.15e-05	198	113	6	2959d6e4992c36040ec9637f5a2daed02b35cf30
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	VSIG4 FMNL2 ARHGEF10L RGL1 MYOF MERTK	1.15e-05	198	113	6	579a22199643440b98e381147779ced630d4ed66
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	VSIG4 RHOQ MYOF CD1D ASGR2 TLR2	1.15e-05	198	113	6	7b61f427ed5ca8ad563e5f112fba950a24c9d956
ToppCell	VE-mono1\|VE / Condition, Cell_class and T cell subcluster	VSIG4 ARHGEF10L RGL1 MYOF ASGR2 TLR2	1.15e-05	198	113	6	c742871b8ec4720b1848991551c7c1f4000ebd85
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_Resident_macrophages\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	HEXA VSIG4 RGL1 CD1D AP2A2 MERTK	1.15e-05	198	113	6	30bf78d4d657cf5140549d3dbf43d4f00482e300
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma-stromal_macrophage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HEXA VSIG4 FMNL2 RGL1 AP2A2 MERTK	1.18e-05	199	113	6	2649afa3ccda78e9d1df26127b66cbfa0c6cd01d
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_monocytic\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	VSIG4 FMNL2 MYOF CD1D MFGE8 ASGR2	1.18e-05	199	113	6	7dde5c02fcae64cd2d68f607500f2a46b97851fd
ToppCell	COPD-Myeloid-Macrophage\|COPD / Disease state, Lineage and Cell class	FMNL2 RHOQ RGL1 AP2A2 TLR2 MERTK	1.18e-05	199	113	6	4b9c53fb4f44190d2f6ad4d52b13be01ebe4955e
ToppCell	Transverse-Macrophage-LYVE1_Macrophage\|Transverse / Region, Cell class and subclass	GPR85 VSIG4 ARHGEF10L RGL1 MYOF TLR2	1.18e-05	199	113	6	facf79c256db5ae57bdb613e86ec90616a6f67ca
ToppCell	Transverse-(6)_Macrophage-(61)_LYVE1_Macrophage\|Transverse / shred on region, Cell_type, and subtype	GPR85 VSIG4 ARHGEF10L RGL1 MYOF TLR2	1.18e-05	199	113	6	dcc2a7f4d1fa30aaaad655dd59c5a2b039d264bf
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	VSIG4 FMNL2 MYOF CD1D MFGE8 ASGR2	1.18e-05	199	113	6	84879280851380e5bfe6bd48b6bbf57aedf6e003
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	VSIG4 FMNL2 RGL1 MYOF TLR2 MERTK	1.18e-05	199	113	6	80ed217d28ba1c07facd0e103c25a02658dd848d
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	VSIG4 RHOQ RGL1 MYOF TLR2 MERTK	1.18e-05	199	113	6	18b6087863fda22e3e2a2167e7daeb347df1d95b
ToppCell	Biopsy_Control_(H.)-Epithelial-Differentiating_Ciliated\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	CFAP47 B9D1 VWA3B SPAG17 DNAH5 PLK4	1.22e-05	200	113	6	a552a99f5e4fa00dfb7775e5a3e1f62f1530d104
ToppCell	mLN-(6)_Macrophage-(61)_LYVE1_Macrophage\|mLN / shred on region, Cell_type, and subtype	VSIG4 RGL1 MYOF ASGR2 TLR2 MERTK	1.22e-05	200	113	6	a20f5ec61d492d8a2adf695ec304b5d57296aa8f
ToppCell	mLN-Macrophage-LYVE1_Macrophage\|mLN / Region, Cell class and subclass	VSIG4 RGL1 MYOF ASGR2 TLR2 MERTK	1.22e-05	200	113	6	89cf739a3c2f5d30e547404f2f2ec6500cd1d65d
ToppCell	COVID-19-Myeloid-MoAM2,_CCL18\|Myeloid / Condition, Lineage and Cell class	HEXA VSIG4 RGL1 AP2A2 MERTK ATP5PD	1.22e-05	200	113	6	a60346c5ea7a3dae1ad3c5dc6c6eca65b64c6888
ToppCell	COVID-19-Myeloid-MoAM2,_CCL18\|COVID-19 / Condition, Lineage and Cell class	HEXA VSIG4 TCIRG1 RGL1 AP2A2 MERTK	1.22e-05	200	113	6	b0a50622d00335843efad86bc56a1e910019984b
ToppCell	10x5'v1-week_14-16-Myeloid_macrophage-stroma-stromal_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	HEXA VSIG4 FMNL2 RGL1 AP2A2 MERTK	1.22e-05	200	113	6	af743dfef7e7cfaef1c494999757123f93a213e3
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CA12 SLC26A4 MYOF VWA3B	2.27e-05	65	113	4	f14b28214f80ed23501ab28ff254c206f70d77b2
ToppCell	10x5'-blood-Myeloid_Mac\|blood / Manually curated celltypes from each tissue	CACNA1D GPR85 VSIG4 MERTK ALPK2	3.80e-05	148	113	5	1ae2d7475e030e2de49940f3287b02953dbf3c65
ToppCell	10x5'-blood-Myeloid_Mac-Intermediate_macrophages\|blood / Manually curated celltypes from each tissue	CACNA1D GPR85 VSIG4 MERTK ALPK2	3.80e-05	148	113	5	b801f38d249a02c4ceceb242cabbbc88418e5fd1
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEK4 KICS2 PLCG1 MERTK CPNE7	5.03e-05	157	113	5	a426c54fd1545093d41426e9620862f71bd06f6b
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pcp2_(Purkinje_Neurons)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ABCA12 TNMD B4GALNT3 ALPK2	5.95e-05	83	113	4	46de51665a1502f3132f2d56c85e8ba365431b3d
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pcp2_(Purkinje_Neurons)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ABCA12 TNMD B4GALNT3 ALPK2	5.95e-05	83	113	4	1ab841bab56a05dc0e7551a1408e5c5570f548e0
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pcp2_(Purkinje_Neurons)--\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ABCA12 TNMD B4GALNT3 ALPK2	5.95e-05	83	113	4	7a38262bca74f0e26ac07d936753dc83fde3cb3d
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	VSIG4 SLC7A2 ZNF630 INTS5 LRP2	6.55e-05	166	113	5	f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Lancl3_(Cortical_Subplate_pyramidal_cells)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ABCA12 ITGA2 TNMD SCARA5	7.48e-05	88	113	4	fcc15c5c30517c63a835b28627c5f779d9bcd17e
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Lancl3_(Cortical_Subplate_pyramidal_cells)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ABCA12 ITGA2 TNMD SCARA5	7.48e-05	88	113	4	7838c65160cf81c02b923fc34f566c0610c8d81b
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWA3B SPAG17 DNAH5 PLK4 PLXNB1	7.54e-05	171	113	5	1854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CFAP47 DNAH1 VWA3B SPAG17 DNAH5	8.18e-05	174	113	5	f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	B4GALNT4 ACACA GDPD2 MYOF PLXNB1	8.18e-05	174	113	5	207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CFAP47 DNAH1 VWA3B SPAG17 DNAH5	8.40e-05	175	113	5	c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HEXA VSIG4 TCIRG1 RHOQ MERTK	8.87e-05	177	113	5	382f0d6bbff01e84b0c7840e74ac865864e6da89
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNMD DNAH1 LRP2 SPAG17 DNAH5	8.87e-05	177	113	5	ae01c19403a09f7ba5e4beafdfcd1b8eebdadcb7
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL2 MYOF TLR2 PYGB ALPK2	8.87e-05	177	113	5	14fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNMD DNAH1 LRP2 SPAG17 DNAH5	8.87e-05	177	113	5	bd3d07bdef6e903995d4bbfb6ff3a5e1d9fb70cc
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	VSIG4 ASGR2 TLR2 CMAHP	9.27e-05	93	113	4	1a112bd4e5e63826efad0338ce99d7a7ad9c72b9
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	VSIG4 ASGR2 TLR2 CMAHP	9.27e-05	93	113	4	9c566fc2a8c7630bea28e8e46df55454aa409bc1
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	VSIG4 ASGR2 TLR2 CMAHP	9.27e-05	93	113	4	d102a0a015a2866e3fe549ac8796b9a0d5923d7e
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	VSIG4 ASGR2 TLR2 CMAHP	9.27e-05	93	113	4	0967a93dcc72d2d8f12d56de186ec1af55c36001
ToppCell	Frontal_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	VSIG4 ASGR2 TLR2 CMAHP	9.27e-05	93	113	4	613c827a643a7b6d70ef932cfa1762e90bc5a338
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	VSIG4 FMNL2 RGL1 TLR2 MERTK	9.60e-05	180	113	5	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell	Ciliated_cells-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	CFAP47 DNAH1 VWA3B SPAG17 DNAH5	9.60e-05	180	113	5	bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ACACA ITGA2 MYOF B4GALNT3 PLS1	9.85e-05	181	113	5	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CA12 GDPD2 KICS2 PACC1 PLXNB1	1.01e-04	182	113	5	c00e503f442d44fbae73c5e2dc85be69e294e67a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 STXBP4 CPS1 MYOF TLR2	1.06e-04	184	113	5	8fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	VSIG4 RHOQ MYOF TDRD6 MERTK	1.09e-04	185	113	5	7bff05d8d34616adbaa0ea0b69eb30aa906bb9f8
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 SLC7A2 VWA3B SPAG17 DNAH5	1.09e-04	185	113	5	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic\|GI_large-bowel / Manually curated celltypes from each tissue	VSIG4 ARHGEF10L RGL1 MYOF TLR2	1.18e-04	188	113	5	d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HEXA VSIG4 TCIRG1 TLR2 MERTK	1.18e-04	188	113	5	3f47395db7e6159fc95810545bad4b6e028464c5
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes\|GI_large-bowel / Manually curated celltypes from each tissue	VSIG4 ARHGEF10L RGL1 MYOF TLR2	1.18e-04	188	113	5	0bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 RAB11FIP2 ITGA2 ARHGEF10L B4GALNT3	1.18e-04	188	113	5	4154f4787483c7e076e87a187733a9f666742c3d
ToppCell	COVID-19-lung-Ciliated\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFAP47 VWA3B SPAG17 DNAH5 BTG4	1.21e-04	189	113	5	a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 GDPD2 MYOF TLR2 MERTK	1.21e-04	189	113	5	e059be2965cca70ff5576df055d0af1775b76e00
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 RAB11FIP2 ITGA2 ARHGEF10L B4GALNT3	1.21e-04	189	113	5	90aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 CACNA1D STXBP4 ITGA2 B4GALNT3	1.21e-04	189	113	5	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	COVID-19-Heart-Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	VSIG4 RGL1 AP2A2 TLR2 MERTK	1.21e-04	189	113	5	2586f4088721c5debec86c2b211b739fd33713eb
ToppCell	Control-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	EXT1 MYOF SLC7A2 AFAP1 CMAHP	1.24e-04	190	113	5	4e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ACVR2A MYOF SLC7A2 AFAP1	1.24e-04	190	113	5	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|368C / Donor, Lineage, Cell class and subclass (all cells)	VSIG4 RGL1 AP2A2 TLR2 MERTK	1.24e-04	190	113	5	cbba3d94a4c3e0b0d14f3b7c60dba5d6e097c5e3
ToppCell	LV-08._Macrophage\|World / Chamber and Cluster_Paper	VSIG4 RGL1 AP2A2 TLR2 MERTK	1.27e-04	191	113	5	e7a0bc46ba9ba772636a583f3387748418e18832
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TCIRG1 RHOQ CD1D ASGR2 TLR2	1.27e-04	191	113	5	63d4226a8b59f648bdc9f41e4b2d750dfa342034
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	VSIG4 RGL1 AP2A2 TLR2 MERTK	1.30e-04	192	113	5	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC7A2 MFGE8 PYGB MERTK PLXNB1	1.30e-04	192	113	5	261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCell	LV-08._Macrophage\|LV / Chamber and Cluster_Paper	VSIG4 FMNL2 AP2A2 TLR2 MERTK	1.30e-04	192	113	5	7be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCell	multiciliated\|World / shred by cell class for turbinate	SLC7A2 B9D1 VWA3B SPAG17 DNAH5	1.30e-04	192	113	5	0f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE8 FLT1 F8 MFGE8 TDRD6	1.30e-04	192	113	5	5890076929598e88fe9d59a4e4e858b446746ce9
ToppCell	Control-Myeloid-cMonocyte\|Control / Disease state, Lineage and Cell class	FLT1 EXT1 CD1D ASGR2 TLR2	1.30e-04	192	113	5	ad04c9c4bdebf94615cee1904ca48197e62c923b
ToppCell	Control-Myeloid-Monocyte-derived_macrophages\|Control / group, cell type (main and fine annotations)	FMNL2 RGL1 AP2A2 TLR2 MERTK	1.33e-04	193	113	5	a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 ITGA2 VWA3B SPAG17 DNAH5	1.33e-04	193	113	5	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	15-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	SLC7A2 B9D1 VWA3B SPAG17 DNAH5	1.33e-04	193	113	5	aa3acc7571405169efb656d214f3a8cbf988362e
ToppCell	facs-Liver-Non-hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 FMNL2 F8 RGL1 MERTK	1.33e-04	193	113	5	8084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCell	Leuk-UTI\|World / Disease, Lineage and Cell Type	GPR85 VSIG4 IRF1 FMNL2 MYOF	1.33e-04	193	113	5	26119a0b5d7684022fd16b8b73a0ef5a7d70f3d1
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-FDC\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FMNL2 MFGE8 SCARA5 DNAH5 ALPK2	1.36e-04	194	113	5	f9fbb043411546d8c9e0321a64165d411f44aeb7
ToppCell	COVID-19-Heart-Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	VSIG4 RGL1 AP2A2 TLR2 MERTK	1.36e-04	194	113	5	f09675cd472200363c458952f00d2e41990800ee
ToppCell	facs-Marrow-KLS-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STXBP4 PTOV1 MFGE8 PRMT5 DNTT	1.36e-04	194	113	5	c9ebdcc2ea600975dade68a41fa65d1f8a5a5926
ToppCell	COVID_vent-Myeloid-Monocytic-CD16+_Monocyte\|COVID_vent / Disease condition, Lineage, Cell class and subclass	VSIG4 FMNL2 RGL1 MYOF MERTK	1.36e-04	194	113	5	b133d3d198360269cc449a75d34c29be377d91e0
ToppCell	LA-08._Macrophage\|World / Chamber and Cluster_Paper	VSIG4 RGL1 AP2A2 TLR2 MERTK	1.36e-04	194	113	5	c1805572bcc11b1cd29083329d7b5911489fb758
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 SLC7A2 VWA3B SPAG17 DNAH5	1.36e-04	194	113	5	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CA12 CACNA1D ITGA2 ARHGEF10L PLXNB1	1.36e-04	194	113	5	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VSIG4 RGL1 AP2A2 TLR2 MERTK	1.36e-04	194	113	5	c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCell	COVID-19-Epithelial-Ciliated_cells\|COVID-19 / Condition, Lineage and Cell class	CFAP47 SLC7A2 VWA3B SPAG17 DNAH5	1.36e-04	194	113	5	43be5fbd51dd58839cb03ca3ddd05a458e1ddb74
Drug	prochlorperazine dimaleate salt; Up 200; 10uM; HL60; HT_HG-U133A	VSIG4 TFIP11 ACVR2A BTN3A2 RGL1 AP2A2 PYGB PLK4	5.21e-06	195	111	8	1156_UP
Drug	Folic acid [59-30-3]; Down 200; 9uM; MCF7; HT_HG-U133A	IRF1 TFIP11 ITGA2 ARHGEF10L MYOF ZNF35 ZNF75D ATM	5.62e-06	197	111	8	7201_DN
Drug	Acenocoumarol [152-72-7]; Down 200; 11.4uM; PC3; HT_HG-U133A	CA12 IRF1 ACVR2A HIRA MYOF MFGE8 B9D1 ZNF75D	6.05e-06	199	111	8	2077_DN
Drug	ZSTK474	PIK3CA PIK3CB PRKDC	9.27e-06	9	111	3	ctd:C510150
Drug	N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide	PIK3CA PIK3CB PRKDC	1.32e-05	10	111	3	ctd:C558744
Drug	NB-598	HEXA GPR85 APOB	2.40e-05	12	111	3	CID006443223
Drug	NVP & EFV	FLT1 ACVR2A F8 PIK3CA PIK3CB QRSL1	2.86e-05	121	111	6	CID000492400
Drug	rosiglitazone; Up 200; 10uM; HL60; HT_HG-U133A	ACVR2A HIRA AP2A2 LRP2 B9D1 PYGB PLK4	4.41e-05	192	111	7	1174_UP
Drug	Dipyrone [5907-38-0]; Up 200; 12uM; PC3; HT_HG-U133A	CA12 APOB MFGE8 PLCG1 IL36G PLK4 BTG4	4.71e-05	194	111	7	4310_UP
Drug	Tridihexethyl chloride; Up 200; 11.4uM; HL60; HT_HG-U133A	EXT1 ACVR2A BTN3A1 RGL1 B9D1 PLCG1 CPNE7	5.02e-05	196	111	7	2964_UP
Drug	17-AAG; Up 200; 1uM; PC3; HT_HG-U133A	HSPH1 BTN3A1 ARHGEF10L AFAP1 PACC1 MERTK IL36G	5.02e-05	196	111	7	5919_UP
Drug	Denatonium benzoate [3734-33-6]; Down 200; 9uM; PC3; HT_HG-U133A	MFGE8 AFAP1 PIK3CB PLK4 PLXNB1 CPNE7 KIF1C	5.02e-05	196	111	7	5061_DN
Drug	Ethoxyquin [91-53-2]; Down 200; 18.4uM; HL60; HT_HG-U133A	RAB11FIP2 ITGA2 CPS1 CD1D ZNF75D PLK4 COG4	5.19e-05	197	111	7	2559_DN
Drug	Arecoline hydrobromide [300-08-3]; Up 200; 17uM; PC3; HT_HG-U133A	BTN3A2 HIRA MYOF MFGE8 AFAP1 PACC1 KIF1C	5.19e-05	197	111	7	6322_UP
Drug	(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; PC3; HT_HG-U133A	MFGE8 AFAP1 B9D1 PLCG1 PLK4 PLXNB1 CPNE7	5.19e-05	197	111	7	6663_DN
Drug	Mevalonic-D, L acid lactone [674-26-0]; Down 200; 30.8uM; PC3; HT_HG-U133A	HIRA MYOF MFGE8 AP2A2 LRP2 ZNF75D PLCG1	5.36e-05	198	111	7	5738_DN
Drug	Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A	CACNA1D EXT1 HIRA MFGE8 SETD2 ZNF35 PLK4	5.36e-05	198	111	7	4729_DN
Drug	orthovanadate	TCIRG1 ABCC6 DNAH1 SETD2 PIK3CA PIK3CB SCARA5 PYGB PLCG1 IL36G	5.40e-05	435	111	10	CID000061672
Drug	Methantheline bromide [53-46-3]; Up 200; 9.6uM; MCF7; HT_HG-U133A	CPS1 PGR MYOF SLC7A2 AP2A2 ATM PLK4	5.53e-05	199	111	7	3560_UP
Drug	Beta-Escin [11072-93-8]; Down 200; 3.2uM; MCF7; HT_HG-U133A	CACNA1D ABCA12 CPS1 IPO9 AP2A2 PLK4 CPNE7	5.71e-05	200	111	7	4364_DN
Drug	Azaguanine-8 [134-58-7]; Up 200; 26.2uM; MCF7; HT_HG-U133A	CA12 SLC26A4 TFIP11 EXT1 IPO9 PLCG1 CPNE7	5.71e-05	200	111	7	7444_UP
Drug	oxadiazon	ACACA TCIRG1 ILVBL	6.03e-05	16	111	3	CID000029732
Drug	AC1LWLPQ	HSPH1 TNMD SLC7A2	6.03e-05	16	111	3	CID001778727
Drug	2 Md	NCOA6 ITGA2	7.04e-05	3	111	2	CID005289549
Drug	2-hydroxyestradiol 2,3-dibenzoate	TNMD PGR	7.04e-05	3	111	2	CID000067095
Drug	LY294002	FLT1 GPR85 TCIRG1 ITGA2 SETD2 PIK3CA PIK3CB TLR2 PLCG1 PRKDC ATM IL36G DNTT	7.28e-05	748	111	13	CID000003973
Drug	CTK2H7103	NCOA6 PSMD3 PRPF6 ITGA2 ABCC6 HIRA MFGE8	7.53e-05	209	111	7	CID005462309
Drug	AMPK inhibitor	NCOA6 ACACA GPR85 TCIRG1 ABCC6	7.54e-05	89	111	5	CID011524144
Drug	tauroursocholate	CA12 APOB ABCC6 PIK3CA PIK3CB MERTK	8.17e-05	146	111	6	CID000005246
Disease	colorectal cancer (is_implicated_in)	XPO1 YTHDF1 SETD2 PIK3CA TLR2 ATM	5.41e-06	121	107	6	DOID:9256 (is_implicated_in)
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	DNHD1 FLT1 SETD2 PIK3CA ATM MERTK	1.71e-05	148	107	6	C0279702
Disease	Benign neoplasm of stomach	IRF1 PIK3CA ATM	3.04e-05	17	107	3	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	IRF1 PIK3CA ATM	3.04e-05	17	107	3	C0496905
Disease	Carcinoma in situ of stomach	IRF1 PIK3CA ATM	3.04e-05	17	107	3	C0154060
Disease	Adenoid Cystic Carcinoma	SETD2 PIK3CA PYGB PRKDC ATM	3.27e-05	100	107	5	C0010606
Disease	Stomach Carcinoma	IRF1 PIK3CA ATM	5.88e-05	21	107	3	C0699791
Disease	urate measurement	CA12 NCOA6 RAB11FIP2 EXT1 ACVR2A CPS1 BTN3A2 DNAH1 LRP2 PYGB CMAHP TECPR1	9.96e-05	895	107	12	EFO_0004531
Disease	ergothioneine measurement	IRF1 CPS1 DNAH5	1.13e-04	26	107	3	EFO_0021163
Disease	L-arginine measurement, amino acid measurement	CPS1 SLC7A2	1.29e-04	5	107	2	EFO_0005134, EFO_0006524
Disease	Malignant neoplasm of breast	NCOA6 FLT1 STXBP4 BTN3A2 PGR RGL1 MFGE8 SETD2 PIK3CA PIK3CB PACC1 ATM PLXNB1	1.40e-04	1074	107	13	C0006142
Disease	type 2 diabetes mellitus (is_marker_for)	CACNA1D APOB ITGA2 F8 PIK3CB	1.41e-04	136	107	5	DOID:9352 (is_marker_for)
Disease	Breast Carcinoma	FLT1 STXBP4 BTN3A2 PGR MFGE8 SETD2 PIK3CA PIK3CB ATM	1.53e-04	538	107	9	C0678222
Disease	lung non-small cell carcinoma (is_implicated_in)	CA12 IRF1 XPO1 PLCG1 ATM	1.56e-04	139	107	5	DOID:3908 (is_implicated_in)
Disease	stomach cancer (is_marker_for)	XPO1 CD1D SETD2 PIK3CA ATM	1.72e-04	142	107	5	DOID:10534 (is_marker_for)
Disease	amino acid measurement	ABCA12 ITGA2 ACVR2A CPS1 NEK4 RGL1 SLC7A2 LRP2 PRKDC CMAHP	1.82e-04	678	107	10	EFO_0005134
Disease	Eye Diseases, Hereditary	LRP2 PLK4	1.94e-04	6	107	2	C0015398
Disease	bipolar disorder	CPNE8 STXBP4 PSMD3 MAU2 BTN3A2 BTN3A1 CMAHP ATP5PD CPNE7	2.58e-04	577	107	9	MONDO_0004985
Disease	alkaline phosphatase measurement	B4GALNT4 SLC26A4 APOB CPS1 AZIN1 MFGE8 ASGR2 PYGB B4GALNT3 CMAHP COG4 ALPK2	3.17e-04	1015	107	12	EFO_0004533
Disease	Disease Exacerbation	FLT1 ABCC6 PTOV1 PIK3CA PA2G4	3.45e-04	165	107	5	C0235874
Disease	Leydig cell tumor (is_marker_for)	FLT1 PRMT5	3.60e-04	8	107	2	DOID:2696 (is_marker_for)
Disease	basophil count	IRF1 PSMD3 EXT1 MAU2 ACVR2A SETD2 PACC1 PRKDC	3.85e-04	483	107	8	EFO_0005090
Disease	Adenocarcinoma of large intestine	NEK4 PIK3CA PRKDC ATM	4.20e-04	96	107	4	C1319315
Disease	asthma, sex interaction measurement	RAB11FIP2 IRF1	4.61e-04	9	107	2	EFO_0008343, MONDO_0004979
Disease	hepatocellular carcinoma (is_implicated_in)	XPO1 AZIN1 PIK3CA TLR2 PLCG1	5.27e-04	181	107	5	DOID:684 (is_implicated_in)
Disease	Head and Neck Carcinoma	PIK3CA PIK3CB	5.75e-04	10	107	2	C3887461
Disease	Mammary Carcinoma, Human	FLT1 STXBP4 BTN3A2 PGR MFGE8 SETD2 PIK3CA ATM	6.66e-04	525	107	8	C4704874
Disease	Mammary Neoplasms, Human	FLT1 STXBP4 BTN3A2 PGR MFGE8 SETD2 PIK3CA ATM	6.66e-04	525	107	8	C1257931
Disease	Mammary Neoplasms	FLT1 STXBP4 BTN3A2 PGR MFGE8 SETD2 PIK3CA ATM	6.82e-04	527	107	8	C1458155
Disease	Gastric cancer	IRF1 PIK3CA	7.01e-04	11	107	2	cv:C0024623
Disease	Neoplasm of stomach	IRF1 PIK3CA	7.01e-04	11	107	2	cv:C0038356
Disease	gastric adenocarcinoma (is_implicated_in)	IRF1 XPO1	7.01e-04	11	107	2	DOID:3717 (is_implicated_in)
Disease	Sensory hearing loss	SLC26A4 LRP2	7.01e-04	11	107	2	C1691779
Disease	GASTRIC CANCER	IRF1 PIK3CA	7.01e-04	11	107	2	613659
Disease	diabetic retinopathy (is_implicated_in)	FLT1 APOB ITGA2	8.03e-04	50	107	3	DOID:8947 (is_implicated_in)
Disease	creatinine measurement, glomerular filtration rate	NCOA6 ACVR2A CPS1 LRP2	8.85e-04	117	107	4	EFO_0004518, EFO_0005208
Disease	Adenocarcinoma of lung (disorder)	FLT1 PIK3CA PRKDC ATM ATP5PD	9.44e-04	206	107	5	C0152013
Disease	Colorectal Carcinoma	ACACA ABCA12 APOB ABCC6 ARHGEF10L PIK3CA TLR2 LRP2 SPAG17	1.05e-03	702	107	9	C0009402
Disease	Chronic Lymphocytic Leukemia	XPO1 PIK3CA ATM	1.06e-03	55	107	3	C0023434
Disease	angina pectoris	FLT1 APOB IPO9 CMAHP	1.13e-03	125	107	4	EFO_0003913
Disease	Neoplasm of lung	IRF1 PIK3CA	1.15e-03	14	107	2	cv:C0024121
Disease	Lung cancer	IRF1 PIK3CA	1.15e-03	14	107	2	cv:C0242379
Disease	LUNG CANCER	IRF1 PIK3CA	1.15e-03	14	107	2	211980
Disease	Kuhnt-Junius degeneration (is_marker_for)	FLT1 TLR2	1.15e-03	14	107	2	DOID:10873 (is_marker_for)
Disease	Sarcomatoid Renal Cell Carcinoma	DNHD1 FLT1 SETD2 PIK3CA	1.23e-03	128	107	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	DNHD1 FLT1 SETD2 PIK3CA	1.23e-03	128	107	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	DNHD1 FLT1 SETD2 PIK3CA	1.23e-03	128	107	4	C1266044
Disease	Papillary Renal Cell Carcinoma	DNHD1 FLT1 SETD2 PIK3CA	1.23e-03	128	107	4	C1306837
Disease	Renal Cell Carcinoma	DNHD1 FLT1 SETD2 PIK3CA	1.23e-03	128	107	4	C0007134
Disease	Replication Error Phenotype	ACVR2A SETD2	1.33e-03	15	107	2	C1721098
Disease	Microsatellite Instability	ACVR2A SETD2	1.33e-03	15	107	2	C0920269
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	RFX7 SETD2	1.71e-03	17	107	2	DOID:0060307 (is_implicated_in)
Disease	Prostatic Neoplasms	SLC26A4 XPO1 SETD2 PIK3CA PIK3CB LRP2 PRKDC ATM	1.84e-03	616	107	8	C0033578
Disease	Malignant neoplasm of prostate	SLC26A4 XPO1 SETD2 PIK3CA PIK3CB LRP2 PRKDC ATM	1.84e-03	616	107	8	C0376358
Disease	basophil count, eosinophil count	IRF1 PSMD3 XPO1 PRKDC ATM	1.89e-03	241	107	5	EFO_0004842, EFO_0005090
Disease	Hemangiosarcoma	FLT1 PLCG1	1.92e-03	18	107	2	C0018923
Disease	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer	ABCA12 APOB PLCG1	2.04e-03	69	107	3	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Disease	breast cancer (is_implicated_in)	NCOA6 PIK3CA TLR2 ATM	2.21e-03	150	107	4	DOID:1612 (is_implicated_in)
Disease	esophagus squamous cell carcinoma (is_marker_for)	CA12 XPO1 ATM	2.49e-03	74	107	3	DOID:3748 (is_marker_for)
Disease	mean reticulocyte volume	STXBP4 VSIG4 ZNF510 MAU2 XPO1 AZIN1 PIK3CA ATM IPO11	2.53e-03	799	107	9	EFO_0010701
Disease	colorectal cancer (is_marker_for)	SETD2 PIK3CB PLCG1 ATM	2.60e-03	157	107	4	DOID:9256 (is_marker_for)
Disease	BREAST CANCER	PIK3CA ATM	2.62e-03	21	107	2	114480
Disease	disease of metabolism (implicated_via_orthology)	YTHDF1 YTHDF3	2.62e-03	21	107	2	DOID:0014667 (implicated_via_orthology)
Disease	neonatal abstinence syndrome	FMNL2 RSU1 SLC7A2	2.79e-03	77	107	3	EFO_0005799
Disease	Granulomatous Slack Skin	PLCG1 ATM	2.87e-03	22	107	2	C0376407
Disease	diastolic blood pressure, systolic blood pressure	CACNA1D FLT1 RGL1 MFGE8 C2CD3 VWA3B CMAHP CPNE7	3.08e-03	670	107	8	EFO_0006335, EFO_0006336
Disease	complex trait	APOB MAU2 BTN3A2 TNRC6A PYGB	3.13e-03	271	107	5	EFO_0010578
Disease	Carcinoma of lung	IRF1 PIK3CA	3.14e-03	23	107	2	C0684249
Disease	Sensorineural Hearing Loss (disorder)	SLC26A4 LRP2	3.14e-03	23	107	2	C0018784
Disease	Lymphoma, T-Cell, Cutaneous	PLCG1 ATM	3.14e-03	23	107	2	C0079773
Disease	cystatin C measurement	SCAF8 CPS1 DNAH1 LRP2 PYGB CPNE7	3.51e-03	402	107	6	EFO_0004617
Disease	chronic obstructive pulmonary disease	CACNA1D FLT1 TPRN IRF1 AFAP1 SCARA5 CAPZA3 DNAH5	3.62e-03	688	107	8	EFO_0000341

Protein segments in the cluster

Peptide	Gene	Start	Entry
KSKWIFQVNPFLTQV	CAPZA3	171	Q96KX2
WNTALPQVQVVEVGQ	ARHGEF10L	601	Q9HCE6
QIQWSNNKGENIPTV	BTN3A1	176	O00481
LLIWQQQQQKLESVP	BRD3OS	26	A0A1B0GUI7
VVPVKNQARWVQQFI	B4GALNT3	791	Q6L9W6
KHSQWQNVVAQIKPF	AZIN1	51	O14977
QIQPEEAKTAIWQVL	ALPK2	1481	Q86TB3
NSWEEQKFIVQHTNP	ASGR2	216	P07307
QKFIVQHTNPFNTWI	ASGR2	221	P07307
DPWVQQFILNLEQQM	COG4	646	Q9H9E3
VQEQKAVWQLLSSFP	ABCA12	256	Q86UK0
PLVLAVQSKEQAEQW	AFAP1	226	Q8N556
VAVKIFPIQDKQSWQ	ACVR2A	216	P27037
IDWVAFAEIIPQNQK	ATP5PD	11	O75947
SEAKIIQQAGQVWFP	ACACA	2006	Q13085
PFVQAQWSRQQVKEE	DNHD1	166	Q96M86
VLTIWRQPQNQQKVA	SLC7A2	541	P52569
WKQLSNPQQEVQNIF	AP2A2	841	O94973
TPDQKFIQWFQRQQL	RGL1	471	Q9NZL6
INSNQIPGLIWINKE	IRF1	16	P10914
LVKPGNQNTQVTEAW	PA2G4	156	Q9UQ80
WNKNAVHVNLFETPV	MFGE8	186	Q08431
PVNIFWVQNSSRVNE	MERTK	226	Q12866
DQWFKNQLLPELQVI	IPO11	471	Q9UI26
VVNVELPIEANLVWQ	HSPH1	591	Q92598
WTVFRNPVQISQEQL	CA12	236	O43570
VAFVNWINKALENDP	PLS1	126	Q14651
WINIIKNPQFVFDVQ	PLXNB1	1986	O43157
QLLPENQVVEWFVQI	NEK4	101	P51957
PVDWNFAQKELLEQQ	KIF1C	621	O43896
DNVSVNLFVVNKPWL	GDPD2	441	Q9HCC8
QVNNPKEWLQVDFQK	F8	2241	P00451
NWLRDVTIFDKQVQP	LRP2	2321	P98164
AVQQFINPKGNWLLV	ITGA2	51	P17301
IVVIWVIVSPNNDKQ	PIK3CA	191	P42336
NSGPVQIVNNKFLAW	PTOV1	246	Q86YD1
FIQKVQDIVTANPWN	PACC1	291	Q9H813
QAQVSEWKFLPSLVN	KICS2	201	Q96MD2
QKVEPWNSVRVTFNI	NCOA6	86	Q14686
MWQIPQEFVKLQVSQ	PGR	801	P06401
WPSKILGQIELVQQQ	DNAH1	916	Q9P2D7
QKSQNDFDLVPWLQI	ATM	401	Q13315
QADINKIVQILPWEQ	APOB	571	P04114
LPWEQNEQVKNFVAS	APOB	581	P04114
VAQAPWKAVNTLNEA	CPS1	1101	P31327
KPITGTINDLNQQVW	IL36G	21	Q9NZH8
LLNSDIFWKPQEAVQ	ILVBL	381	A1L0T0
VVENTDSPIWNFQQQ	C2CD3	1681	Q4AC94
LPFSEVINWNQAAVI	EXT1	366	Q16394
AKWFEKQVQFPVIQL	QRSL1	491	Q9H0R6
PLWVNLAIQVLNQDK	CD1D	156	P15813
TEVVKNNLNPVWEAF	CPNE7	271	Q9UBL6
VEKNPNAVVTLENWQ	PRMT5	391	O14744
QIQWSNAKGENIPAV	BTN3A2	176	P78410
WVALKPNQINGTVFN	FMNL2	631	Q96PY5
EIGVPESNIQVWFKN	DUXB	51	A0A1W2PPF3
TEEQIKVWTANPQQF	IPO9	371	Q96P70
KPVQFVAAVSQNWTF	GPR85	216	P60893
KKISIVTNWNAPQNI	CCDC168	5811	Q8NDH2
VDNTVVIWNAVKFPE	HIRA	151	P54198
KSQDVRQALVWNFPI	B9D1	56	Q9UPM9
LWQKNNVFKSEIIQP	SCAF8	116	Q9UPN6
PLQADLTEQVWKVQD	SCARA5	116	Q6ZMJ2
KAWLISQQIPQFEDV	MAU2	91	Q9Y6X3
IPIKNQTNDKWTFQV	CFAP47	2336	Q6ZTR5
NQPDWLTQIQDIANK	CACNA1D	546	Q01668
VVKNTLNPVWQAFKI	CPNE8	201	Q86YQ8
WNQPQDVVEEKILSA	DNAH5	421	Q8TE73
VVWQEVFDNKVKIQP	HEXA	371	P06865
GQKQVFKAENNPWVT	RSU1	206	Q15404
VNPASFQNVKEEWVP	RHOQ	91	P17081
VGQNPFVWDVKAIQA	TDRD6	891	O60522
KVQKIITNVWDIFQP	SLC9B1P1	131	A6NJY1
EWLQAQKVQVSSQPE	DNTT	86	P04053
VPQEAWVQNTSVVEN	ABCC6	696	O95255
QANPNSEEIWLAAVK	PRPF6	636	O94906
ATALNPIEQDQKWQS	SMG1	1301	Q96Q15
PIEQDQKWQSITENV	SMG1	1306	Q96Q15
QWAFEPDVFQKQAIL	SKIV2L	306	Q15477
QQVLSEFIRANPKAW	INTS5	126	Q6P9B9
VWENNNPFQIVLVKG	PIK3CB	326	P42338
PQTETVQQWFGNLQI	PLK4	471	O00444
WEIAFIRQKSDNIQP	STXBP4	101	Q6ZWJ1
KIWEPSLIAAQFNQN	SPAG17	16	Q6Q759
NVNKPQLWNIFNQVT	GTF3C3	696	Q9Y5Q9
VENLKQPFQSWLQIP	BTG4	171	Q9NY30
FIVPVKNQARWVAQF	B4GALNT4	826	Q76KP1
NINVVPFGIWQQVDK	CMAHP	136	Q9Y471
IEQNEQWVVPQVKVE	TNMD	216	Q9H2S6
LWPEQDIKDSFQQVI	ZNF431	116	Q8TF32
QQVHSENIKVWAPVQ	ZNF35	36	P13682
PNQVWDSIIQQATKN	XPO1	661	O14980
FEVKWIFVKDVPNNQ	YTHDF3	501	Q7Z739
QQQQHVTSWPGKQVE	VEZF1	351	Q14119
VSKSVFPEQANNNEW	PSMD3	271	O43242
IQVDWNSELPVKVNV	SLC26A4	636	O43511
TPAQTAAWRKQIFQQ	TECPR1	571	Q7Z6L1
IFNQKIVNGWQVEEA	PYGB	166	P11216
QKTEFVVDNGLNPVW	PLCG1	1126	P19174
NPNGWQQITKDSEFI	RFX7	681	Q2KHR2
QAQKWFPTHVQVTVL	RAB11FIP2	6	Q7L804
IWYKQQTNNQEPIKV	VSIG4	176	Q9Y279
DVPNKSWQQTTFQNR	SETD2	1211	Q9BYW2
FLKWSIKQITPQQQE	PRKDC	1036	P78527
DFTQEEWQQLNPAQK	ZNF630	16	Q2M218
QFLSILPKETQNWVQ	ZNF75D	96	P51815
VAFSKWQEQALEQAP	TPRN	666	Q4KMQ1
TQEEWQQMAPVQKNL	ZNF510	56	Q9Y2H8
EFNIIRVSQEPVKWQ	VWA3B	176	Q502W6
QITWFKNNHKIQQEP	FLT1	691	P17948
QEQQALAKVLIDWPA	TLR2	546	O60603
WDQSSQPVFENVNVK	UIMC1	201	Q96RL1
QEEAWINPFVKQFSN	TNRC6A	1196	Q8NDV7
QLIFPKLQKEVENWN	TFIP11	526	Q9UBB9
RPAVKAAQNEIWQTF	TCIRG1	426	Q13488
VQWIFVKDVPNNQLR	YTHDF1	476	Q9BYJ9
NIIEKNANPEWNQVV	MYOF	411	Q9NZM1
NANPEWNQVVNLQIK	MYOF	416	Q9NZM1
WNQVVNLQIKFPSVC	MYOF	421	Q9NZM1