Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	flavin-dependent sulfhydryl oxidase activity	QSOX1 GFER	1.62e-05	3	47	2	GO:0016971
GeneOntologyMolecularFunction	thiol oxidase activity	QSOX1 GFER	8.09e-05	6	47	2	GO:0016972
GeneOntologyMolecularFunction	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	QSOX1 GFER	2.94e-04	11	47	2	GO:0016670
GeneOntologyMolecularFunction	poly(A)-specific ribonuclease activity	PAN2 CNOT6L	4.16e-04	13	47	2	GO:0004535
GeneOntologyMolecularFunction	microtubule motor activity	KIF14 KIF2A DNAI2	5.99e-04	70	47	3	GO:0003777
GeneOntologyMolecularFunction	ubiquitin-specific protease binding	MARCHF6 RAD23A	1.00e-03	20	47	2	GO:1990381
GeneOntologyCellularComponent	9+2 non-motile cilium	STRC STRCP1	4.43e-04	14	47	2	GO:0097732
GeneOntologyCellularComponent	kinocilium	STRC STRCP1	4.43e-04	14	47	2	GO:0060091
Domain	Evr1_Alr	QSOX1 GFER	1.86e-05	3	47	2	PF04777
Domain	ERV/ALR_sulphydryl_oxidase	QSOX1 GFER	1.86e-05	3	47	2	IPR017905
Domain	-	QSOX1 GFER	1.86e-05	3	47	2	1.20.120.310
Domain	ERV_ALR	QSOX1 GFER	1.86e-05	3	47	2	PS51324
Domain	STI1_HS-bd	UBQLN3 RAD23A	2.75e-04	10	47	2	IPR006636
Domain	STI1	UBQLN3 RAD23A	2.75e-04	10	47	2	SM00727
Domain	UBA	UBQLN3 RAD23A	2.58e-03	30	47	2	SM00165
Domain	UBA	UBQLN3 RAD23A	3.70e-03	36	47	2	PF00627
Domain	UBIQUITIN_1	UBQLN3 RAD23A	3.90e-03	37	47	2	PS00299
Domain	ARM_REPEAT	APC ARMCX5	4.55e-03	40	47	2	PS50176
Domain	Kinesin_motor_CS	KIF14 KIF2A	4.77e-03	41	47	2	IPR019821
Domain	UBQ	UBQLN3 RAD23A	5.24e-03	43	47	2	SM00213
Domain	Kinesin-like_fam	KIF14 KIF2A	5.24e-03	43	47	2	IPR027640
Domain	KINESIN_MOTOR_1	KIF14 KIF2A	5.48e-03	44	47	2	PS00411
Domain	-	KIF14 KIF2A	5.48e-03	44	47	2	3.40.850.10
Domain	UBA	UBQLN3 RAD23A	5.48e-03	44	47	2	IPR015940
Domain	Kinesin_motor_dom	KIF14 KIF2A	5.48e-03	44	47	2	IPR001752
Domain	Kinesin	KIF14 KIF2A	5.48e-03	44	47	2	PF00225
Domain	KISc	KIF14 KIF2A	5.48e-03	44	47	2	SM00129
Domain	KINESIN_MOTOR_2	KIF14 KIF2A	5.48e-03	44	47	2	PS50067
Domain	Armadillo	APC ARMCX5	6.23e-03	47	47	2	IPR000225
Domain	UBA	UBQLN3 RAD23A	6.23e-03	47	47	2	PS50030
Domain	ubiquitin	UBQLN3 RAD23A	6.23e-03	47	47	2	PF00240
Domain	UBIQUITIN_2	UBQLN3 RAD23A	8.16e-03	54	47	2	PS50053
Domain	Ubiquitin_dom	UBQLN3 RAD23A	9.37e-03	58	47	2	IPR000626
Domain	UBA-like	UBQLN3 RAD23A	1.13e-02	64	47	2	IPR009060
Pathway	REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY	PAN2 CNOT6L DCP1A	2.21e-04	54	31	3	MM15089
Pathway	REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY	PAN2 CNOT6L DCP1A	2.47e-04	56	31	3	M839
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TNIK APC KIF14 QSER1 CNOT6L NEBL CDK12 JMJD1C UGGT1 DCP1A BANP	3.76e-09	733	48	11	34672954
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	APC KMT2A PARP4 KIF2A PPP6R1 QSER1 ZC3H4 CDK12 JMJD1C	2.30e-07	650	48	9	38777146
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KIF14 KMT2A QSER1 CDK12 JMJD1C SNX1 SCAF4 DCP1A	7.94e-07	549	48	8	38280479
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	MYT1L APC PAN2 SPIRE1 KIF2A QSER1 CNOT6L UBE2Q1 UGGT1 DCP1A	1.85e-06	1084	48	10	11544199
Pubmed	Systematic analysis of cancer-specific synthetic lethal interactions provides insight into personalized anticancer therapy.	APC GFER	1.87e-06	2	48	2	36181326
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	1.87e-06	2	48	2	34910522
Pubmed	Functional analysis of the two reciprocal fusion genes MLL-NEBL and NEBL-MLL reveal their oncogenic potential.	KMT2A NEBL	1.87e-06	2	48	2	23340173
Pubmed	TNIK inhibition abrogates colorectal cancer stemness.	TNIK APC	1.87e-06	2	48	2	27562646
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	1.87e-06	2	48	2	11687802
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TNIK KMT2A PPP6R1 NEBL ZC3H4 CDK12 SNX1 SCAF4 DCP1A	4.58e-06	934	48	9	33916271
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	5.59e-06	3	48	2	30801007
Pubmed	Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.	STRC STRCP1	1.12e-05	4	48	2	18849963
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	TNIK KIF14 KIF2A STIL	1.18e-05	101	48	4	24613305
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	MYT1L LIMCH1 PPP6R1 ZC3H4	1.33e-05	104	48	4	10470851
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	MYT1L TNIK THSD7A ZC3H4 CDK12	1.48e-05	225	48	5	12168954
Pubmed	An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.	STRC STRCP1	1.86e-05	5	48	2	24920589
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	APC KIF14 KMT2A SPIRE1 KIF2A LIMCH1 STIL DCP1A	2.14e-05	861	48	8	36931259
Pubmed	Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.	KMT2A QSER1 ZC3H4 RAD23A	2.26e-05	119	48	4	23508102
Pubmed	Impact of WIN site inhibitor on the WDR5 interactome.	KMT2A KIF2A IARS1	2.93e-05	43	48	3	33472061
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	APC KIF14 KMT2A SPIRE1 KIF2A LIMCH1 CNOT6L NEBL CDK12 SCAF4	3.10e-05	1497	48	10	31527615
Pubmed	Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.	STRC STRCP1	5.19e-05	8	48	2	21165971
Pubmed	Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment.	PAN2 CNOT6L	6.67e-05	9	48	2	21078877
Pubmed	Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation.	PAN2 PAIP2	6.67e-05	9	48	2	17785442
Pubmed	Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells.	PAN2 DCP1A	6.67e-05	9	48	2	18625844
Pubmed	MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.	KIF14 KIF2A PPP6R1	6.85e-05	57	48	3	29089450
Pubmed	miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT.	PAN2 CNOT6L	8.33e-05	10	48	2	21984185
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PAN2 SPIRE1 FAM149B1 ZC3H4 CDK12 MARCHF6	8.59e-05	529	48	6	14621295
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	QSOX1 KMT2A LIMCH1 ZC3H4 CDK12 SCAF4 DCP1A	8.76e-05	774	48	7	15302935
Pubmed	Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.	KIF14 KIF2A	1.02e-04	11	48	2	15843429
Pubmed	Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.	STRC STRCP1	1.02e-04	11	48	2	31776257
Pubmed	Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.	STRC STRCP1	1.02e-04	11	48	2	31448880
Pubmed	Combinatorial CRISPR screen identifies fitness effects of gene paralogues.	KMT2A ZC3H4 CDK12 DCP1A	1.28e-04	186	48	4	33637726
Pubmed	NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs.	CNOT6L DCP1A	1.44e-04	13	48	2	20133598
Pubmed	The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.	APC KMT2A	1.44e-04	13	48	2	16510874
Pubmed	DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.	TCP10L KIAA0408 STRC ANKRD45 PAIP2	1.45e-04	364	48	5	31391242
Pubmed	Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.	APC KMT2A	1.94e-04	15	48	2	16510875
Pubmed	GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.	PAN2 CNOT6L	1.94e-04	15	48	2	21981923
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	TNIK APC PPP6R1 DCP1A	2.00e-04	209	48	4	36779422
Pubmed	Partial transcriptome of the developing pituitary gland.	APC SLC47A1	2.21e-04	16	48	2	11161784
Pubmed	Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.	STRC STRCP1	2.50e-04	17	48	2	20856818
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	APC KIF14 PPP6R1 JMJD1C DCP1A	2.74e-04	418	48	5	34709266
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TNIK APC KIF2A LIMCH1 PPP6R1 QSER1 ZC3H4	3.34e-04	963	48	7	28671696
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	APC PPP6R1 QSER1 JMJD1C	3.50e-04	242	48	4	34011540
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	KMT2A ZC3H4 CDK12 SCAF4	4.02e-04	251	48	4	31076518
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	APC LIMCH1 JMJD1C SNX1	4.33e-04	256	48	4	33397691
Pubmed	The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells.	KIF14 KMT2A	4.63e-04	23	48	2	17203973
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	KIF14 ZC3H4 CDK12 SCAF4 DCP1A	4.77e-04	472	48	5	38943005
Pubmed	Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.	KMT2A QSER1 BANP	4.80e-04	110	48	3	26841866
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	KMT2A QSER1 ZC3H4 JMJD1C	5.14e-04	268	48	4	33640491
Pubmed	Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.	KIF14 KIF2A	5.48e-04	25	48	2	9275178
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	KMT2A KIF2A LIMCH1 ZC3H4 SCAF4	6.03e-04	497	48	5	36774506
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	APC PAN2 NRBP1 ZC3H4 CDK12	6.36e-04	503	48	5	16964243
Pubmed	NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.	QSER1 JMJD1C	6.40e-04	27	48	2	23395962
Pubmed	Novel interactors and a role for supervillin in early cytokinesis.	KIF14 KMT2A	6.89e-04	28	48	2	20309963
Pubmed	Alternatively spliced isoforms of WT1 control podocyte-specific gene expression.	THSD7A NEBL	6.89e-04	28	48	2	25993318
Pubmed	Human transcription factor protein interaction networks.	KMT2A PPP6R1 QSER1 JMJD1C IARS1 SCAF4 DCP1A BANP	6.94e-04	1429	48	8	35140242
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	KMT2A KIF2A QSER1 JMJD1C IARS1 SCAF4 RAD23A	7.49e-04	1103	48	7	34189442
Pubmed	Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.	RIBC1 KIAA0408 NRBP1 KIF2A NEBL DCP1A BANP RAD23A	8.61e-04	1477	48	8	31515488
Pubmed	Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition.	PAIP2 DCP1A	9.01e-04	32	48	2	21460039
Pubmed	Sf3b4 regulates chromatin remodeler splicing and Hox expression.	KMT2A JMJD1C	9.01e-04	32	48	2	37167859
Pubmed	Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.	CNOT6L THSD7A DCP1A BANP	1.07e-03	326	48	4	17015433
Pubmed	Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking.	MCFD2 UGGT1	1.08e-03	35	48	2	22337587
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	PPP6R1 QSER1 JMJD1C IARS1 DCP1A BANP	1.12e-03	857	48	6	25609649
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	MYT1L KIAA0408 TNIK	1.20e-03	151	48	3	17043677
Pubmed	All kinesin superfamily protein, KIF, genes in mouse and human.	KIF14 KIF2A	1.20e-03	37	48	2	11416179
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	KMT2A ZC3H4 JMJD1C DCP1A	1.26e-03	341	48	4	32971831
Pubmed	A SMAD1/5-YAP signalling module drives radial glia self-amplification and growth of the developing cerebral cortex.	APC SPIRE1	1.27e-03	38	48	2	32541003
Pubmed	A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis.	STRC STRCP1	1.27e-03	38	48	2	38346162
Pubmed	Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.	KMT2A ZC3H4 CDK12	1.32e-03	156	48	3	37108203
Interaction	SFN interactions	KIAA0408 TNIK APC NRBP1 KIF14 KMT2A SPIRE1 KIF2A DCP1A BANP	3.50e-06	692	47	10	int:SFN
Interaction	CNOT1 interactions	RIBC1 KIF14 PPP6R1 STIL CNOT6L PAIP2 DCP1A	6.35e-06	305	47	7	int:CNOT1
Interaction	TOB2 interactions	RIBC1 PAN2 CNOT6L	1.32e-05	20	47	3	int:TOB2
Interaction	CNOT9 interactions	RIBC1 APC PAN2 CNOT6L JMJD1C PAIP2	1.54e-05	231	47	6	int:CNOT9
Interaction	TNRC6C interactions	PAN2 KIF14 STIL CNOT6L DCP1A	1.70e-05	138	47	5	int:TNRC6C
Interaction	CNOT10 interactions	RIBC1 PPP6R1 STIL CNOT6L PAIP2	1.89e-05	141	47	5	int:CNOT10
Interaction	EGLN3 interactions	APC KIF14 PARP4 KIF2A PPP6R1 STIL UBE2Q1 CDK12 JMJD1C GFER UGGT1 DCP1A	3.02e-05	1296	47	12	int:EGLN3
Interaction	FHL2 interactions	TCP10L RIBC1 APC QSER1 CNOT6L DCP1A BANP	3.43e-05	396	47	7	int:FHL2
Interaction	GARRE1 interactions	PAN2 KIF14 STIL CNOT6L DCP1A	4.26e-05	167	47	5	int:GARRE1
Interaction	ZFP36 interactions	RIBC1 PAN2 STIL CNOT6L DCP1A	6.25e-05	181	47	5	int:ZFP36
Interaction	AGO1 interactions	KIF14 PPP6R1 CNOT6L PAIP2 DCP1A	6.58e-05	183	47	5	int:AGO1
Interaction	NAA40 interactions	TNIK KMT2A LIMCH1 PPP6R1 NEBL ZC3H4 CDK12 SNX1 SCAF4 DCP1A	6.95e-05	978	47	10	int:NAA40
Interaction	BTG3 interactions	RIBC1 NRBP1 CNOT6L BANP	7.99e-05	98	47	4	int:BTG3
Interaction	SMG7 interactions	STIL CNOT6L ZC3H4 JMJD1C PAIP2 DCP1A	9.33e-05	319	47	6	int:SMG7
Interaction	PHF21A interactions	APC KIF14 PPP6R1 JMJD1C DCP1A BANP	1.39e-04	343	47	6	int:PHF21A
Interaction	DCTN1 interactions	KIAA0408 APC KIF14 KIF2A PPP6R1 NEBL SNX1	1.42e-04	497	47	7	int:DCTN1
Interaction	DBX2 interactions	KIF14 ZC3H4	1.48e-04	8	47	2	int:DBX2
Interaction	MEX3B interactions	RIBC1 PAN2 CNOT6L PAIP2 DCP1A	1.63e-04	222	47	5	int:MEX3B
Cytoband	15q15.3	STRC STRCP1	3.16e-04	25	48	2	15q15.3
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	APC ARMCX5	2.62e-03	43	32	2	409
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF14 KIF2A	2.99e-03	46	32	2	622
GeneFamily	LIM domain containing	LIMCH1 NEBL	4.88e-03	59	32	2	1218
ToppCell	ASK454-Epithelial\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	KIAA0408 LIMCH1 ARMCX5 NEBL DNAI2	1.52e-06	182	48	5	ab15316cff989b61ff397a866d7ca8b49c13e981
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LIMCH1 ANKRD45 NEBL GFER	2.28e-05	154	48	4	44d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	TNIK APC PARP4 CDK12	4.77e-05	186	48	4	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SPIRE1 LIMCH1 THSD7A NEBL	4.98e-05	188	48	4	58ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPIRE1 LIMCH1 THSD7A NEBL	5.18e-05	190	48	4	b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	TNIK KMT2A CNOT6L JMJD1C	5.40e-05	192	48	4	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TNIK SPIRE1 LIMCH1 NEBL	5.62e-05	194	48	4	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIF14 STIL ANKRD45 DNAI2	6.08e-05	198	48	4	f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35\|World / Primary Cells by Cluster	MYT1L KMT2A PAIP2 MARCHF6	6.08e-05	198	48	4	de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TNIK KMT2A KIF2A CNOT6L	6.20e-05	199	48	4	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	mild-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TNIK KMT2A KIF2A CNOT6L	6.33e-05	200	48	4	d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TNIK KMT2A KIF2A CNOT6L	6.33e-05	200	48	4	109f673a4967ffa52270a0b4f818b3461288db44
Drug	Methotrexate [59-05-2]; Down 200; 8.8uM; HL60; HG-U133A	PAN2 KIF14 KIF2A ZC3H4 CDK12 SCAF4	2.45e-06	189	47	6	2041_DN
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	2.27e-06	2	45	2	DOID:0110471 (implicated_via_orthology)
Disease	Microcephaly	KIF14 KIF2A IARS1	1.48e-04	67	45	3	C0025958
Disease	response to anticonvulsant	TDRD15 THSD7A NEBL	3.00e-04	85	45	3	GO_0036277
Disease	Neurodevelopmental Disorders	MYT1L KMT2A ZC3H4	3.91e-04	93	45	3	C1535926
Disease	Autosomal Recessive Primary Microcephaly	KIF14 STIL	5.15e-04	22	45	2	C3711387
Disease	Antiglaucoma preparations and miotics use measurement	KMT2A THSD7A	7.22e-04	26	45	2	EFO_0009944
Disease	interleukin-8 measurement	MYT1L KMT2A	1.03e-03	31	45	2	EFO_0004811
Disease	gait measurement	KIF14 NEBL JMJD1C	1.56e-03	150	45	3	EFO_0007680
Disease	coffee consumption measurement, tea consumption measurement	ZC3H4 JMJD1C	2.07e-03	44	45	2	EFO_0006781, EFO_0010091
Disease	cholesterol to total lipids in large VLDL percentage	TDRD15 JMJD1C	2.16e-03	45	45	2	EFO_0022236
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	TDRD15 JMJD1C	2.26e-03	46	45	2	EFO_0008317, EFO_0008596, EFO_0020943
Disease	cholesteryl esters to total lipids in small VLDL percentage	TDRD15 JMJD1C	2.56e-03	49	45	2	EFO_0022256
Disease	free cholesterol in large LDL measurement	TDRD15 JMJD1C	2.77e-03	51	45	2	EFO_0022176
Disease	cholesterol to total lipids in small VLDL percentage	TDRD15 JMJD1C	2.77e-03	51	45	2	EFO_0022242
Disease	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	NRBP1 TDRD15	2.77e-03	51	45	2	EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Disease	triglycerides to total lipids in very large VLDL percentage	TDRD15 JMJD1C	2.98e-03	53	45	2	EFO_0022340
Disease	cholesteryl esters to total lipids in very large VLDL percentage	TDRD15 JMJD1C	2.98e-03	53	45	2	EFO_0022258

Protein segments in the cluster

Peptide	Gene	Start	Entry
LQPTLQPEMQLEHGA	BANP	501	Q8N9N5
IPQMAQLLNIHSNPE	CDK12	1131	Q9NYV4
EDPENPHHEQAMQLL	ANKRD45	56	Q5TZF3
ELNIDIMPNPELAEQ	DNAI2	26	Q9GZS0
VLAPLQSMQQNQDPE	DCP1A	456	Q9NPI6
MIENLVNNPNVKEHP	ARMCX5	356	Q6P1M9
HQEQFIQMLNEPPGE	RAD23A	276	P54725
PARDLPQTMDQIQDQ	PAIP2	76	Q9BPZ3
EDGFPMQELQVLQPQ	QSER1	561	Q2KHR3
PPEHMAELQRNEQEQ	QSOX1	621	O00391
LTQLHQDMQELEIPQ	PAN2	621	Q504Q3
MDNHLPNLVNLNEDP	KIF14	796	Q15058
NKPEAEMSPQELQLH	MCFD2	61	Q8NI22
IVMNDQVLEPQNVDP	JMJD1C	221	Q15652
VTNIPHGDPMINNDQ	KIAA0408	206	Q6ZU52
NLNDPDFNPVQEMIH	MARCHF6	456	O60337
GMQNVEIPHLPQDFE	PARP4	136	Q9UKK3
MVDPEDPDNVQSNHL	IFNAR2	456	P48551
MPNENIPELAAELVQ	NRBP1	481	Q9UHY1
IMHHPPNQIDDLETQ	KIF2A	566	O00139
QEREENSHTEQPPLM	KMT2A	1806	Q03164
QNEPLTQKPHQQEME	SCAF4	401	O95104
MPNHQVLLGPEEDQD	PRAP1	131	Q96NZ9
DKMPEANQLHLPNLN	LIMCH1	731	Q9UPQ0
QPNVNDLLVHGMPLQ	FAM149B1	351	Q96BN6
QELENQHLCPEQMLE	THSD7A	1451	Q9UPZ6
MLEEFPQQMPDLLQH	TDRD15	196	B5MCY1
EMPPLQQQIIRLHQE	TCP10L	46	Q8TDR4
MLQQVPENINFPAEE	IARS1	1	P41252
VQAYLHMPPENLQQL	STRC	731	Q7RTU9
HMPPENLQQLVLSAE	STRC	736	Q7RTU9
QSDQQMRQEEPLPEH	SLC47A1	516	Q96FL8
PTPEQQQDMAQFIHL	GFER	121	P55789
ELRIMPPVQENDNGN	APC	1521	P25054
NFMLDNLAVHPEQLP	CNOT6L	156	Q96LI5
EMVNNENPPLINHLE	STIL	446	Q15468
EQLMKHPFIRDQPNE	TNIK	281	Q9UKE5
DLLTENPQVAQHPMA	RIBC1	251	Q8N443
LQRIVNHPTMLQDPD	SNX1	246	Q13596
PHPQQLQEQEEMQEE	SOGA3	341	Q5TF21
PPLEQLIDHMANTVE	SPIRE1	151	Q08AE8
VHEPLSPQQLQQQDM	ZC3H4	561	Q9UPT8
MIQVQDSPEPDQLLA	PPP6R1	226	Q9UPN7
VQAYLHMPPENLQQL	STRCP1	731	A6NGW2
HMPPENLQQLVLSAE	STRCP1	736	A6NGW2
QPLLEHLQPQLATMN	PLIN5	76	Q00G26
QLQDEIQPQLPLLMH	UBQLN3	496	Q9H347
PHDQDVVEYIMNQPN	UGGT1	676	Q9NYU2
LDQDLPNNMIHQVPI	UGGT1	1451	Q9NYU2
NLPQHPDVEMLDQPL	UBE2Q1	161	Q7Z7E8
PQQNMNIRQHVRPEE	MYT1L	351	Q9UL68
SLANIQLPHMDPINE	MYT1L	1131	Q9UL68
QLPHMDPINEQNFDA	MYT1L	1136	Q9UL68
KDIQNMHDPVSDLPN	NEBL	271	O76041