Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnuclear receptor activity

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

5.27e-1660349GO:0004879
GeneOntologyMolecularFunctionligand-activated transcription factor activity

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

6.18e-1661349GO:0098531
GeneOntologyMolecularFunctionretinoic acid-responsive element binding

RARA RXRA RXRB RXRG

2.44e-107344GO:0044323
GeneOntologyMolecularFunctionnuclear steroid receptor activity

NR4A3 NR2C1 RXRA RXRB RXRG

5.46e-1025345GO:0003707
GeneOntologyMolecularFunctionzinc ion binding

NR4A2 ZCCHC4 NR4A3 NR2C1 RARA RARB HNF4G ENPP1 RXRA RXRB RXRG OTUD7B OTUD7A

9.89e-108913413GO:0008270
GeneOntologyMolecularFunctiontransition metal ion binding

NR4A2 ZCCHC4 NR4A3 NR2C1 RARA RARB HNF4G ENPP1 RXRA RXRB RXRG OTUD7B OTUD7A

3.18e-0811893413GO:0046914
GeneOntologyMolecularFunctionscavenger receptor activity

LRP1 SCARF2 ENPP1 STAB1

1.20e-0727344GO:0005044
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

NR4A2 RARB RXRA RXRB

2.25e-0655344GO:0042974
GeneOntologyMolecularFunctioncargo receptor activity

LRP1 SCARF2 ENPP1 STAB1

1.29e-0585344GO:0038024
GeneOntologyMolecularFunctionnuclear receptor binding

NR4A2 NR4A3 RARB RXRA RXRB

1.52e-05187345GO:0016922
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

NR4A2 NR4A3 NR2C1 KMT2D RARA RARB HNF4G RXRA RXRB RXRG

8.25e-0514123410GO:0000981
GeneOntologyMolecularFunctiontranscription coactivator binding

NR4A3 RARA RXRA

1.05e-0454343GO:0001223
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

1.74e-041244349GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

2.05e-041271349GO:0000987
GeneOntologyMolecularFunctiontranscription factor binding

NR4A2 NR4A3 RARA RARB RXRA RXRB TLE4

2.33e-04753347GO:0008134
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 STAB1

3.33e-0416342GO:0005041
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

NR4A2 NR4A3 RARB RXRA RXRB TLE4

4.01e-04582346GO:0140297
GeneOntologyMolecularFunctionnuclear vitamin D receptor binding

RXRA RXRB

4.23e-0418342GO:0042809
GeneOntologyMolecularFunctionnuclear glucocorticoid receptor binding

NR4A2 NR4A3

5.25e-0420342GO:0035259
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

5.70e-041459349GO:0000977
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 STAB1

5.79e-0421342GO:0030228
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

NR4A2 NR4A3 RARB RXRA RXRB

6.55e-04417345GO:0061629
GeneOntologyMolecularFunctionnuclear retinoid X receptor binding

NR4A2 RARB

6.96e-0423342GO:0046965
GeneOntologyMolecularFunctionK63-linked polyubiquitin modification-dependent protein binding

OTUD7B OTUD7A

8.91e-0426342GO:0070530
GeneOntologyMolecularFunctionretinoic acid binding

RARA RXRA

1.03e-0328342GO:0001972
GeneOntologyMolecularFunctionnuclear thyroid hormone receptor binding

RXRA RXRB

1.53e-0334342GO:0046966
GeneOntologyMolecularFunctiontranscription coregulator binding

NR4A3 RARA RXRA

1.72e-03140343GO:0001221
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

NR4A2 NR4A3 KMT2D HNF4G RXRB

2.42e-03560345GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

NR4A2 NR4A3 KMT2D HNF4G RXRB

2.53e-03566345GO:0001216
GeneOntologyMolecularFunctionchromatin DNA binding

RARA RXRA RXRB

2.84e-03167343GO:0031490
GeneOntologyMolecularFunctionretinoid binding

RARA RXRA

3.02e-0348342GO:0005501
GeneOntologyMolecularFunctionisoprenoid binding

RARA RXRA

3.15e-0349342GO:0019840
GeneOntologyMolecularFunctionpolyubiquitin modification-dependent protein binding

OTUD7B OTUD7A

4.53e-0359342GO:0031593
GeneOntologyMolecularFunctionmodification-dependent protein binding

FAM156A OTUD7B OTUD7A

5.12e-03206343GO:0140030
GeneOntologyMolecularFunctioncoreceptor activity

LRP1 CD80

6.68e-0372342GO:0015026
GeneOntologyMolecularFunctioncalcium ion binding

LRP1 CELSR1 ATP2A1 ENPP1 STAB1

8.27e-03749345GO:0005509
GeneOntologyBiologicalProcessretinoic acid receptor signaling pathway

NR2C1 RARA RARB RXRA RXRB RXRG

3.35e-1138346GO:0048384
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

NR4A2 NR4A3 NR2C1 VPS18 KMT2D RARA RARB HNF4G RXRA RXRB RXRG

3.71e-114163411GO:0030522
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

NR4A3 NR2C1 VPS18 KMT2D RARA RARB RXRA RXRB RXRG

1.59e-10244349GO:0009755
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

NR2C1 VPS18 KMT2D RARA RARB RXRA RXRB RXRG

1.07e-09202348GO:0141193
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

NR4A3 NR2C1 VPS18 KMT2D RXRA RXRB RXRG

5.36e-09155347GO:0043401
GeneOntologyBiologicalProcesscellular response to hormone stimulus

NR4A2 NR4A3 NR2C1 VPS18 KMT2D RARA RARB ENPP1 RXRA RXRB RXRG

1.32e-087273411GO:0032870
GeneOntologyBiologicalProcessventricular cardiac muscle cell differentiation

RARA RARB RXRA RXRB

2.34e-0819344GO:0055012
GeneOntologyBiologicalProcessresponse to hormone

NR4A2 NR4A3 NR2C1 VPS18 KMT2D RARA RARB ATP2A1 ENPP1 RXRA RXRB RXRG

5.06e-0810423412GO:0009725
GeneOntologyBiologicalProcessregulation of myelination

RARA RARB RXRA RXRB RXRG

8.04e-0867345GO:0031641
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

NR4A3 NR2C1 VPS18 KMT2D RXRA RXRB RXRG

1.06e-07239347GO:0071383
GeneOntologyBiologicalProcesscellular response to lipid

NR4A3 NR2C1 VPS18 KMT2D RARA CD80 RXRA RXRB RXRG WNT8B

2.21e-077483410GO:0071396
GeneOntologyBiologicalProcessresponse to organic cyclic compound

NR4A3 NR2C1 VPS18 KMT2D RARA GRM2 ENPP1 RXRA RXRB RXRG WNT8B

5.37e-0710483411GO:0014070
GeneOntologyBiologicalProcessmyelination

RARA RARB ENPP1 RXRA RXRB RXRG

9.83e-07206346GO:0042552
GeneOntologyBiologicalProcessaxon ensheathment

RARA RARB ENPP1 RXRA RXRB RXRG

1.07e-06209346GO:0008366
GeneOntologyBiologicalProcessensheathment of neurons

RARA RARB ENPP1 RXRA RXRB RXRG

1.07e-06209346GO:0007272
GeneOntologyBiologicalProcessmRNA transcription by RNA polymerase II

RARA ENPP1 RXRA RXRB

1.57e-0652344GO:0042789
GeneOntologyBiologicalProcessembryo development

NR4A3 CELSR1 KMT2D RARA RARB TECTA KDF1 ENPP1 RXRA RXRB WNT8B OTUD7B

1.62e-0614373412GO:0009790
GeneOntologyBiologicalProcessmRNA transcription

RARA ENPP1 RXRA RXRB

2.28e-0657344GO:0009299
GeneOntologyBiologicalProcessresponse to retinoic acid

RARA RXRA RXRB RXRG WNT8B

2.30e-06131345GO:0032526
GeneOntologyBiologicalProcessresponse to steroid hormone

NR4A3 NR2C1 VPS18 KMT2D RXRA RXRB RXRG

2.43e-06381347GO:0048545
GeneOntologyBiologicalProcessepithelial cell differentiation

FNDC3B FNDC3A RARA RARB TECTA KDF1 TNMD PTGS1 RXRA

8.21e-06870349GO:0030855
GeneOntologyBiologicalProcessresponse to lipid

NR4A3 NR2C1 VPS18 KMT2D RARA CD80 RXRA RXRB RXRG WNT8B

8.89e-0611263410GO:0033993
GeneOntologyBiologicalProcessepithelium development

FNDC3B FNDC3A CELSR1 RARA RARB TECTA KDF1 TNMD PTGS1 ENPP1 RXRA

1.43e-0514693411GO:0060429
GeneOntologyBiologicalProcessembryonic morphogenesis

NR4A3 CELSR1 RARA RARB TECTA KDF1 ENPP1 WNT8B

1.60e-05713348GO:0048598
GeneOntologyBiologicalProcessresponse to vitamin

RARA ENPP1 RXRA RXRB

2.16e-05100344GO:0033273
GeneOntologyBiologicalProcesscellular response to corticotropin-releasing hormone stimulus

NR4A2 NR4A3

3.94e-056342GO:0071376
GeneOntologyBiologicalProcesspositive regulation of vitamin D receptor signaling pathway

RXRA RXRB

3.94e-056342GO:0070564
GeneOntologyBiologicalProcessresponse to corticotropin-releasing hormone

NR4A2 NR4A3

3.94e-056342GO:0043435
GeneOntologyBiologicalProcesscellular response to organic cyclic compound

NR4A3 NR2C1 VPS18 KMT2D RXRA RXRB RXRG

4.87e-05605347GO:0071407
GeneOntologyBiologicalProcessbone growth

RARA RARB ENPP1

5.54e-0545343GO:0098868
GeneOntologyBiologicalProcessorgan growth

RARA RARB ENPP1 RXRA RXRB

5.87e-05256345GO:0035265
GeneOntologyBiologicalProcesstube development

LRP1 FNDC3B NR4A3 CELSR1 RARA RARB TNMD ENPP1 RXRA STAB1

5.92e-0514023410GO:0035295
GeneOntologyBiologicalProcessregulation of nervous system development

LRP1 FLRT2 RARA RARB RXRA RXRB RXRG

5.98e-05625347GO:0051960
GeneOntologyBiologicalProcessprotein deubiquitination involved in ubiquitin-dependent protein catabolic process

OTUD7B OTUD7A

7.34e-058342GO:0071947
GeneOntologyBiologicalProcessepithelial cell development

FNDC3A RARA RARB KDF1 TNMD

7.42e-05269345GO:0002064
GeneOntologyBiologicalProcessdevelopmental growth

LRP1 KMT2D RARA RARB KDF1 ENPP1 RXRA RXRB

9.15e-05911348GO:0048589
GeneOntologyBiologicalProcessear morphogenesis

NR4A3 CELSR1 TECTA ENPP1

1.16e-04154344GO:0042471
GeneOntologyBiologicalProcessregulation of vitamin D receptor signaling pathway

RXRA RXRB

1.18e-0410342GO:0070562
GeneOntologyBiologicalProcessprotein K11-linked deubiquitination

OTUD7B OTUD7A

1.18e-0410342GO:0035871
GeneOntologyBiologicalProcesssensory organ development

NR4A3 CELSR1 RARA RARB TECTA ENPP1 RXRA

1.58e-04730347GO:0007423
GeneOntologyBiologicalProcessanimal organ morphogenesis

NR4A3 CELSR1 FLRT2 RARA RARB TECTA ENPP1 RXRA WNT8B

1.58e-041269349GO:0009887
GeneOntologyBiologicalProcessvitamin D receptor signaling pathway

RXRA RXRB

1.72e-0412342GO:0070561
GeneOntologyBiologicalProcessWnt signaling pathway

NR4A2 LRP1 CELSR1 ENPP1 TLE4 WNT8B

1.76e-04516346GO:0016055
GeneOntologyBiologicalProcessheart development

LRP1 FLRT2 RARA RARB ENPP1 RXRA RXRB

1.97e-04757347GO:0007507
GeneOntologyBiologicalProcesscardiac muscle cell differentiation

RARA RARB RXRA RXRB

1.99e-04177344GO:0055007
GeneOntologyBiologicalProcessvascular associated smooth muscle cell migration

LRP1 NR4A3 ENPP1

2.08e-0470343GO:1904738
GeneOntologyBiologicalProcesssensory organ morphogenesis

NR4A3 CELSR1 RARB TECTA ENPP1

2.31e-04343345GO:0090596
GeneOntologyBiologicalProcesscellular response to retinoic acid

RARA RXRB WNT8B

2.35e-0473343GO:0071300
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

NR4A2 NR4A3 NR2C1 RARA RARB RXRA TLE4 OTUD7B

2.49e-041053348GO:0000122
GeneOntologyBiologicalProcessembryonic organ morphogenesis

NR4A3 CELSR1 RARB TECTA ENPP1

2.57e-04351345GO:0048562
GeneOntologyBiologicalProcessresponse to nutrient

RARA ENPP1 RXRA RXRB

2.71e-04192344GO:0007584
GeneOntologyBiologicalProcessembryonic organ development

NR4A3 CELSR1 RARA RARB TECTA ENPP1

2.77e-04561346GO:0048568
GeneOntologyBiologicalProcessendochondral bone morphogenesis

RARA RARB ENPP1

2.97e-0479343GO:0060350
GeneOntologyBiologicalProcesscell activation involved in immune response

LRP1 NR4A3 RARA CD80 ENPP1

3.08e-04365345GO:0002263
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

NR4A2 NR4A3 KMT2D RARA RARB HNF4G RXRA RXRB RXRG

3.14e-041390349GO:0045944
GeneOntologyBiologicalProcessadult behavior

NR4A2 NR4A3 GRM2 ENPP1

3.35e-04203344GO:0030534
GeneOntologyBiologicalProcesstube morphogenesis

LRP1 NR4A3 CELSR1 RARA TNMD ENPP1 RXRA STAB1

3.89e-041125348GO:0035239
GeneOntologyBiologicalProcesscirculatory system development

LRP1 FLRT2 RARA RARB TNMD ENPP1 RXRA RXRB STAB1

4.12e-041442349GO:0072359
GeneOntologyBiologicalProcesscellular response to oxygen-containing compound

NR4A2 LRP1 NR4A3 RARA CD80 ENPP1 RXRA RXRB WNT8B

4.29e-041450349GO:1901701
GeneOntologyBiologicalProcessregulation of bone mineralization

ENPP1 RXRA RXRB

4.50e-0491343GO:0030500
GeneOntologyBiologicalProcessglandular epithelial cell differentiation

RARA RARB RXRA

4.50e-0491343GO:0002067
GeneOntologyBiologicalProcesscardiocyte differentiation

RARA RARB RXRA RXRB

4.62e-04221344GO:0035051
GeneOntologyBiologicalProcesslimb development

RARA RARB KDF1 ENPP1

4.86e-04224344GO:0060173
GeneOntologyBiologicalProcessappendage development

RARA RARB KDF1 ENPP1

4.86e-04224344GO:0048736
GeneOntologyBiologicalProcesscell morphogenesis

NR4A2 LRP1 NR4A3 FLRT2 FBLIM1 TECTA TNMD ENPP1

5.79e-041194348GO:0000902
GeneOntologyBiologicalProcesscellular response to vitamin D

RXRA RXRB

6.53e-0423342GO:0071305
GeneOntologyBiologicalProcessgrowth

LRP1 KMT2D RARA RARB KDF1 ENPP1 RXRA RXRB

7.24e-041235348GO:0040007
GeneOntologyBiologicalProcessregulation of biomineral tissue development

ENPP1 RXRA RXRB

8.68e-04114343GO:0070167
GeneOntologyBiologicalProcesspositive regulation of cholesterol efflux

LRP1 RXRA

9.02e-0427342GO:0010875
GeneOntologyBiologicalProcessgrowth plate cartilage development

RARA RARB

1.04e-0329342GO:0003417
GeneOntologyBiologicalProcessbone morphogenesis

RARA RARB ENPP1

1.11e-03124343GO:0060349
GeneOntologyBiologicalProcesscellular response to vitamin

RXRA RXRB

1.19e-0331342GO:0071295
GeneOntologyBiologicalProcessprotein K48-linked deubiquitination

OTUD7B OTUD7A

1.19e-0331342GO:0071108
GeneOntologyBiologicalProcesspositive regulation of T-helper cell differentiation

RARA CD80

1.19e-0331342GO:0045624
GeneOntologyBiologicalProcessear development

NR4A3 CELSR1 TECTA ENPP1

1.19e-03285344GO:0043583
GeneOntologyBiologicalProcessinner ear morphogenesis

NR4A3 CELSR1 TECTA

1.24e-03129343GO:0042472
GeneOntologyBiologicalProcessnegative regulation of stem cell proliferation

RARB KDF1

1.27e-0332342GO:2000647
GeneOntologyBiologicalProcessprotein K63-linked deubiquitination

OTUD7B OTUD7A

1.27e-0332342GO:0070536
GeneOntologyBiologicalProcesstissue morphogenesis

NR4A3 CELSR1 RARA KDF1 ENPP1 RXRA

1.28e-03750346GO:0048729
GeneOntologyBiologicalProcessfat cell differentiation

NR4A2 FNDC3B NR4A3 ENPP1

1.29e-03291344GO:0045444
GeneOntologyBiologicalProcessSertoli cell differentiation

FNDC3A RARA

1.35e-0333342GO:0060008
GeneOntologyBiologicalProcesspositive regulation of vascular associated smooth muscle cell migration

LRP1 NR4A3

1.60e-0336342GO:1904754
GeneOntologyBiologicalProcessnegative regulation of cartilage development

RARA RARB

1.60e-0336342GO:0061037
GeneOntologyBiologicalProcessregulation of intracellular estrogen receptor signaling pathway

VPS18 KMT2D

1.60e-0336342GO:0033146
GeneOntologyBiologicalProcesscell-cell adhesion

NR4A3 FNDC3A CELSR1 RARA FBLIM1 SCARF2 CD80

1.61e-031077347GO:0098609
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

NR4A2 NR4A3 NR2C1 RARA RARB RXRA TLE4 OTUD7B

1.63e-031399348GO:0045892
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

NR4A2 NR4A3 NR2C1 RARA RARB RXRA TLE4 OTUD7B

1.73e-031413348GO:1902679
GeneOntologyBiologicalProcesssmooth muscle cell migration

LRP1 NR4A3 ENPP1

1.74e-03145343GO:0014909
GeneOntologyBiologicalProcessresponse to vitamin D

RXRA RXRB

1.79e-0338342GO:0033280
GeneOntologyBiologicalProcessregulation of ossification

ENPP1 RXRA RXRB

1.81e-03147343GO:0030278
GeneOntologyBiologicalProcessbone mineralization

ENPP1 RXRA RXRB

1.88e-03149343GO:0030282
GeneOntologyBiologicalProcessendochondral bone growth

RARA RARB

1.88e-0339342GO:0003416
GeneOntologyCellularComponenttranscription regulator complex

NR4A2 NR4A3 RARA HNF4G RXRA RXRB RXRG TLE4

3.93e-06596348GO:0005667
GeneOntologyCellularComponentRNA polymerase II transcription regulator complex

RARA RXRA RXRB RXRG TLE4

7.35e-05272345GO:0090575
GeneOntologyCellularComponentchromatin

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

4.53e-041480349GO:0000785
MousePhenohearing/vestibular/ear phenotype

NR4A3 CELSR1 KMT2D RARA TECTA KDF1 HNF4G PTGS1 ENPP1 TLE4

1.56e-059053110MP:0005377
MousePhenoabnormal ear morphology

NR4A3 CELSR1 KMT2D RARA TECTA KDF1 ENPP1

6.06e-05470317MP:0002102
MousePhenopersistent hyperplastic primary vitreous

RARB RXRA

7.10e-056312MP:0010711
MousePhenoabnormal primary vitreous morphology

RARB RXRA

9.93e-057312MP:0009620
MousePhenoperinatal lethality

NR4A2 LRP1 FNDC3B CELSR1 RARA KDF1 ATP2A1 PTGS1 RXRA RXRB

1.05e-0411303110MP:0002081
MousePhenofusion of atlas and odontoid process

RARA RARB

2.12e-0410312MP:0010701
MousePhenoabnormal keratinocyte morphology

KDF1 PTGS1 RXRA

2.27e-0454313MP:0002655
MousePhenofusion of vertebral arches

RARA RARB OTUD7B

3.26e-0461313MP:0004613
MousePhenoabnormal intervertebral disk morphology

RARA ENPP1 RXRA

4.30e-0467313MP:0004173
MousePhenovertebral fusion

RARA RARB ENPP1 OTUD7B

4.39e-04163314MP:0004609
MousePhenoabnormal cricoid cartilage morphology

RARA RXRA

4.91e-0415312MP:0002258
MousePhenoabnormal inner ear morphology

NR4A3 CELSR1 KMT2D TECTA ENPP1

4.95e-04303315MP:0000026
MousePhenoabnormal symphysis morphology

RARA ENPP1 RXRA

5.10e-0471313MP:0030877
MousePhenofused joints

RARA RARB ENPP1 OTUD7B

5.14e-04170314MP:0003189
MousePhenoincreased depression-related behavior

NR4A2 KMT2D HNF4G

5.53e-0473313MP:0014414
MousePhenoabnormal ear physiology

NR4A3 CELSR1 TECTA HNF4G PTGS1 ENPP1 TLE4

6.11e-04684317MP:0003878
Domainzf-C4

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

7.27e-1746349PF00105
DomainNUCLEAR_REC_DBD_1

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

7.27e-1746349PS00031
DomainZnf_hrmn_rcpt

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

7.27e-1746349IPR001628
DomainNuclear_hrmn_rcpt

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

7.27e-1746349IPR001723
DomainZnF_C4

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

7.27e-1746349SM00399
DomainNUCLEAR_REC_DBD_2

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

7.27e-1746349PS51030
Domain-

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

8.98e-17473491.10.565.10
DomainHOLI

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

1.10e-1648349SM00430
DomainNucl_hrmn_rcpt_lig-bd

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

1.10e-1648349IPR000536
DomainHormone_recep

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

1.10e-1648349PF00104
Domain-

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

5.85e-16573493.30.50.10
DomainZnf_NHR/GATA

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

6.92e-1658349IPR013088
DomainRetinoid-X_rcpt/HNF4

HNF4G RXRA RXRB RXRG

1.91e-0910344IPR000003
DomainEGF

LRP1 CELSR1 TECTA PTGS1 STAB1

3.07e-06126345PF00008
DomainCezanne-2

OTUD7B OTUD7A

3.22e-062342IPR033477
DomainNuc_recep-AF1

RXRA RXRG

3.22e-062342PF11825
DomainNuc_recep-AF1

RXRA RXRG

3.22e-062342IPR021780
DomainEGF

LRP1 CELSR1 TECTA SCARF2 PTGS1 STAB1

3.73e-06235346SM00181
DomainEGF-like_dom

LRP1 CELSR1 TECTA SCARF2 PTGS1 STAB1

5.20e-06249346IPR000742
DomainNuc_orph_rcpt

NR4A2 NR4A3

9.64e-063342IPR003070
DomainRetinoic_acid_rcpt

RARA RARB

1.93e-054342IPR003078
DomainLaminin_EGF

CELSR1 SCARF2 STAB1

3.47e-0535343PF00053
DomainEGF_Lam

CELSR1 SCARF2 STAB1

3.47e-0535343SM00180
DomainLaminin_EGF

CELSR1 SCARF2 STAB1

4.45e-0538343IPR002049
DomainEGF_3

LRP1 CELSR1 SCARF2 PTGS1 STAB1

6.24e-05235345PS50026
DomainZnf_A20

OTUD7B OTUD7A

6.72e-057342IPR002653
DomainZF_A20

OTUD7B OTUD7A

6.72e-057342PS51036
DomainZnF_A20

OTUD7B OTUD7A

6.72e-057342SM00259
Domainzf-A20

OTUD7B OTUD7A

6.72e-057342PF01754
DomainEGF_1

LRP1 CELSR1 SCARF2 PTGS1 STAB1

9.18e-05255345PS00022
DomainEGF-like_CS

LRP1 CELSR1 SCARF2 PTGS1 STAB1

1.02e-04261345IPR013032
DomainEGF_2

LRP1 CELSR1 SCARF2 PTGS1 STAB1

1.10e-04265345PS01186
DomainGrowth_fac_rcpt_

LRP1 CELSR1 SCARF2 STAB1

1.79e-04156344IPR009030
DomainOTU

OTUD7B OTUD7A

2.48e-0413342PF02338
DomainOTU

OTUD7B OTUD7A

3.33e-0415342PS50802
DomainOTU_dom

OTUD7B OTUD7A

3.33e-0415342IPR003323
DomainEGF_LAM_2

CELSR1 STAB1

1.36e-0330342PS50027
DomainEGF_LAM_1

CELSR1 STAB1

1.36e-0330342PS01248
DomainEGF_CA

LRP1 CELSR1 STAB1

1.40e-03122343SM00179
DomainEGF-like_Ca-bd_dom

LRP1 CELSR1 STAB1

1.47e-03124343IPR001881
Domainfn3

FNDC3B FNDC3A FLRT2

3.15e-03162343PF00041
DomainFN3

FNDC3B FNDC3A FLRT2

4.57e-03185343SM00060
DomainEGF_extracell

SCARF2 STAB1

5.33e-0360342IPR013111
DomainEGF_2

SCARF2 STAB1

5.33e-0360342PF07974
DomainFN3

FNDC3B FNDC3A FLRT2

5.59e-03199343PS50853
DomainUBA-like

OTUD7B OTUD7A

6.04e-0364342IPR009060
DomainFN3_dom

FNDC3B FNDC3A FLRT2

6.40e-03209343IPR003961
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

4.80e-1653289M8276
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

NR4A2 NR4A3 NR2C1 RARA RARB RXRA RXRB RXRG

2.89e-1448288MM14987
PathwayWP_VITAMIN_A1_AND_A5X_PATHWAYS

RARA RARB RXRA RXRB RXRG

1.27e-136285M48097
PathwayWP_NUCLEAR_RECEPTORS

NR4A2 RARA RARB RXRA RXRB RXRG

9.15e-1138286M39657
PathwayWP_NUCLEAR_RECEPTORS

NR4A2 RARA RARB RXRA RXRB RXRG

9.15e-1138286MM15865
PathwayPID_RXR_VDR_PATHWAY

RARA RARB RXRA RXRB RXRG

1.36e-0926285M162
PathwayPID_RETINOIC_ACID_PATHWAY

RARA RARB RXRA RXRB RXRG

2.92e-0930285M207
PathwayWP_VITAMIN_A_AND_CAROTENOID_METABOLISM

RARA RARB RXRA RXRB RXRG

1.94e-0843285M39554
PathwayREACTOME_SIGNALING_BY_RETINOIC_ACID

RARA RARB RXRA RXRB RXRG

1.94e-0843285M27443
PathwayWP_RETINOL_METABOLISM

RARA RARB RXRA RXRB RXRG

2.18e-0844285MM15851
PathwayREACTOME_SIGNALING_BY_RETINOIC_ACID

RARA RARB RXRA RXRB RXRG

3.81e-0849285MM15186
PathwayKEGG_MEDICUS_VARIANT_PAX8_PPARG_FUSION_TO_PPARG_MEDIATED_TRANSCRIPTION

RXRA RXRB RXRG

7.00e-085283M49023
PathwayREACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS

NR4A2 NR2C1 RARA RXRA

3.29e-0730284M27323
PathwayKEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY

RXRA RXRB RXRG

5.85e-079283M47629
PathwayPID_AR_TF_PATHWAY

NR2C1 RXRA RXRB RXRG

3.41e-0653284M151
PathwayKEGG_NON_SMALL_CELL_LUNG_CANCER

RARB RXRA RXRB RXRG

3.68e-0654284M19818
PathwayREACTOME_GENERIC_TRANSCRIPTION_PATHWAY

NR4A2 NR4A3 NR2C1 KMT2D RARA RARB RXRA RXRB RXRG

1.09e-05768289MM14851
PathwayWP_NONSMALL_CELL_LUNG_CANCER

RARB RXRA RXRB RXRG

1.17e-0572284M39738
PathwayKEGG_SMALL_CELL_LUNG_CANCER

RARB RXRA RXRB RXRG

2.15e-0584284M3228
PathwayKEGG_THYROID_CANCER

RXRA RXRB RXRG

2.48e-0529283M523
PathwayREACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

RARA RARB RXRA RXRB RXRG

3.31e-05191285MM15586
PathwayKEGG_PATHWAYS_IN_CANCER

RARA RARB RXRA RXRB RXRG WNT8B

3.52e-05325286M12868
PathwayWP_SMALL_CELL_LUNG_CANCER

RARB RXRA RXRB RXRG

3.65e-0596284M39834
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_GLUCONEOGENESIS

RXRA RXRB

3.79e-055282M29812
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_LIMIT_CHOLESTEROL_UPTAKE

RXRA RXRB

3.79e-055282M29791
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_TRIGLYCERIDE_LIPOLYSIS_IN_ADIPOSE

RXRA RXRB

3.79e-055282M29792
PathwayBIOCARTA_RARRXR_PATHWAY

RARA RXRA

5.68e-056282MM1447
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS

RARA RXRA

5.68e-056282MM15659
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS

RXRA RXRB

5.68e-056282MM15663
PathwayBIOCARTA_RARRXR_PATHWAY

RARA RXRA

7.94e-057282M6907
PathwayREACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

KMT2D RARA RARB RXRA

9.31e-05122284M29689
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

RXRA RXRB RXRG

1.01e-0446283M239
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

NR4A2 NR4A3 NR2C1 KMT2D RARA RARB RXRA RXRB RXRG

1.05e-041022289MM15436
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS

RXRA RXRB

1.36e-049282M29809
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_LIPOGENESIS

RXRA RXRB

1.36e-049282M29789
PathwayWP_VITAMIN_D_METABOLISM

RXRA RXRB

1.70e-0410282M39352
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

NR4A2 NR4A3 NR2C1 KMT2D RARA RARB HNF4G RXRA RXRB RXRG

2.05e-0413872810M734
PathwayBIOCARTA_CARM1_PATHWAY

RARA RXRA

2.07e-0411282MM1521
PathwayBIOCARTA_EGFR_SMRTE_PATHWAY

RARA RXRA

2.07e-0411282MM1432
PathwayBIOCARTA_EGFR_SMRTE_PATHWAY

RARA RXRA

2.07e-0411282M18837
PathwayWP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM

CELSR1 RARA RARB

2.23e-0460283M40048
PathwayBIOCARTA_CARM1_PATHWAY

RARA RXRA

2.48e-0412282M7968
PathwayREACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

RARA RARB RXRA RXRB RXRG

2.61e-04296285M27869
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

RXRA RXRB

2.93e-0413282MM15622
PathwayWP_PPAR_SIGNALING

RXRA RXRB RXRG

3.09e-0467283M39553
PathwayKEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY

RXRA RXRB RXRG

3.09e-0467283M10462
PathwayKEGG_PPAR_SIGNALING_PATHWAY

RXRA RXRB RXRG

3.37e-0469283M13088
PathwayWP_PPAR_SIGNALING_PATHWAY

RXRA RXRB RXRG

3.98e-0473283MM15995
PathwayWP_CANCER_PATHWAYS

RARA RARB RXRA RXRB RXRG WNT8B

4.03e-04507286M48302
PathwayWP_NONGENOMIC_ACTIONS_OF_125_DIHYDROXYVITAMIN_D3

RXRA RXRB RXRG

4.31e-0475283M39568
PathwayREACTOME_SUMOYLATION

NR4A2 NR2C1 RARA RXRA

4.98e-04189284M27214
PathwayWP_PI3KAKTMTOR_VITAMIN_D3_SIGNALING

CD80 RXRA

8.57e-0422282M39345
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

KMT2D TLE4

1.20e-0326282MM14793
PathwayREACTOME_TGFBR3_EXPRESSION

RARA RXRA

1.39e-0328282M48253
PathwayREACTOME_SUMOYLATION_OF_INTRACELLULAR_RECEPTORS

RARA RXRA

1.39e-0328282MM15042
PathwayWP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY

RARA RARB

1.60e-0330282MM15866
PathwayREACTOME_OVARIAN_TUMOR_DOMAIN_PROTEASES

OTUD7B OTUD7A

1.82e-0332282MM15290
PathwayBIOCARTA_NUCLEARRS_PATHWAY

RARA RARB

1.93e-0333282MM1448
PathwayBIOCARTA_NUCLEARRS_PATHWAY

RARA RARB

2.05e-0334282M16393
PathwayWP_ADIPOGENESIS

RARA RXRA RXRG

2.17e-03131283M39505
PathwayWP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY

RARA RARB

2.17e-0335282M39488
PathwayREACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

RXRA RXRB

2.43e-0337282M29790
PathwayWP_ADIPOGENESIS_GENES

RARA RXRA RXRG

2.46e-03137283MM15970
PathwayREACTOME_OVARIAN_TUMOR_DOMAIN_PROTEASES

OTUD7B OTUD7A

2.69e-0339282M27579
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

KMT2D TLE4

3.12e-0342282M27272
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

KMT2D TLE4 WNT8B

3.68e-03158283MM14791
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

RXRA RXRB

3.89e-0347282M29777
PathwayREACTOME_SIGNALING_BY_TGFBR3

RARA RXRA

4.22e-0349282M48250
PathwayWP_MARKERS_OF_KIDNEY_CELL_LINEAGE

RARA RARB

6.07e-0359282M46460
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

LRP1 STAB1

6.27e-0360282MM14872
Pubmed

Structural variants in the retinoid receptor genes in patients with schizophrenia and other psychiatric diseases.

NR4A2 RARA RARB RXRA RXRB RXRG

3.83e-18734615635645
Pubmed

Retinoic acid signaling is necessary for the development of the organ of Corti.

RARA RARB RXRA RXRB RXRG

6.56e-16534510452855
Pubmed

Systematic immunolocalization of retinoid receptors in developing and adult mouse eyes.

RARA RARB RXRA RXRB RXRG

3.94e-15634511328745
Pubmed

The isolation and characterization of purified heterocomplexes of recombinant retinoic acid receptor and retinoid X receptor ligand binding domains.

RARA RARB RXRA RXRB RXRG

3.94e-1563459153406
Pubmed

Spatial distributions of retinoic acid receptor gene transcripts in the prenatal mouse inner ear.

RARA RARB RXRA RXRB RXRG

3.94e-1563459548551
Pubmed

Functional specificity of the two retinoic acid receptor RAR and RXR families in myogenesis.

RARA RARB RXRA RXRB RXRG

3.94e-1563459464546
Pubmed

Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid.

RARA RARB RXRA RXRB RXRG

3.94e-15634520557428
Pubmed

RAR and RXR selective ligands cooperatively induce apoptosis and neuronal differentiation in P19 embryonal carcinoma cells.

RARA RARB RXRA RXRB RXRG

3.94e-1563458801169
Pubmed

A decade of molecular biology of retinoic acid receptors.

RARA RARB RXRA RXRB RXRG

3.94e-1563458801176
Pubmed

The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development.

RARA RARB RXRA RXRB RXRG

3.94e-1563459806918
Pubmed

A genetic dissection of the retinoid signalling pathway in the mouse.

RARA RARB RXRA RXRB RXRG

3.94e-15634510604193
Pubmed

Effect of retinoid status on the messenger ribonucleic acid expression of nuclear retinoid receptors alpha, beta, and gamma, and retinoid X receptors alpha, beta, and gamma in the mouse testis.

RARA RARB RXRA RXRB RXRG

3.94e-1563459075714
Pubmed

Vitamin A deficiency and mutations of RXRalpha, RXRbeta and RARalpha lead to early differentiation of embryonic ventricular cardiomyocytes.

RARA RARB RXRA RXRB RXRG

1.38e-1473459428411
Pubmed

Differential contributions of AF-1 and AF-2 activities to the developmental functions of RXR alpha.

RARA RARB RXRA RXRB RXRG

1.38e-14734511493527
Pubmed

Retinoid signaling controls mouse pancreatic exocrine lineage selection through epithelial-mesenchymal interactions.

RARA RARB RXRA RXRB RXRG

1.38e-14734512360493
Pubmed

Comparison of the expression patterns of newly identified zebrafish retinoic acid and retinoid X receptors.

RARA RARB RXRA RXRB RXRG

1.38e-14734517195188
Pubmed

Creatine kinase (CK) in skeletal muscle energy metabolism: a study of mouse mutants with graded reduction in muscle CK expression.

RARA RARB RXRA RXRB RXRG

1.38e-1473458090775
Pubmed

Dorsal and ventral rentinoic territories defined by retinoic acid synthesis, break-down and nuclear receptor expression.

RARA RARB RXRA RXRB RXRG

3.67e-14834510490294
Pubmed

Expression of nuclear retinoic acid receptors during mouse odontogenesis.

RARA RARB RXRA RXRB RXRG

3.67e-1483457988794
Pubmed

Retinoids and adipose tissues: metabolism, cell differentiation and gene expression.

RARA RARB RXRA RXRB RXRG

3.67e-14834510094571
Pubmed

Prepubertal testis development relies on retinoic acid but not rexinoid receptors in Sertoli cells.

RARA RARB RXRA RXRB RXRG

3.67e-14834517124491
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

NR4A2 NR4A3 NR2C1 RARA RARB FBLIM1 HNF4G RXRA RXRB RXRG

5.76e-14263341020932939
Pubmed

A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells.

RARA RARB RXRA RXRB RXRG

8.25e-1493457823919
Pubmed

Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter.

RARA RARB RXRA RXRB RXRG

3.02e-131134529093497
Pubmed

Differential expression of transcripts encoding retinoid binding proteins and retinoic acid receptors during placentation of the mouse.

RARA RARB RXRA RXRB RXRG

5.17e-13123459022057
Pubmed

Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor.

RARA RARB RXRA RXRB RXRG

5.17e-131234526427057
Pubmed

Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.

NR4A2 NR4A3 RARA RARB HNF4G RXRA RXRB RXRG

6.17e-1313334815604093
Pubmed

Regulation of prefrontal patterning and connectivity by retinoic acid.

NR4A2 RARA RARB RXRA RXRB RXRG

7.22e-133434634599305
Pubmed

Retinoic acid biosynthetic activity and retinoid receptors in the olfactory mucosa of adult mice.

RARB RXRA RXRB RXRG

7.61e-13434410079186
Pubmed

Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specific ligand.

RARA RARB RXRA RXRB

7.61e-1343448524212
Pubmed

Specific and redundant functions of retinoid X Receptor/Retinoic acid receptor heterodimers in differentiation, proliferation, and apoptosis of F9 embryonal carcinoma cells.

RARA RARB RXRA RXRB

7.61e-1343449348290
Pubmed

The retinoid receptors.

RARA RARB RXRA RXRB

7.61e-1343447967725
Pubmed

Retinoic acid regulates murine enteric nervous system precursor proliferation, enhances neuronal precursor differentiation, and reduces neurite growth in vitro.

RARA RARB RXRA RXRB RXRG

1.31e-121434518561907
Pubmed

Retinoic acid induces prostatic bud formation.

RARA RARB RXRA RXRB RXRG

1.31e-121434518393306
Pubmed

LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.

RARA RARB RXRA RXRB RXRG

1.31e-121434521923909
Pubmed

Understanding abnormal retinoid signaling as a causative mechanism in congenital diaphragmatic hernia.

RARA RARB RXRA RXRB RXRG

1.96e-121534519448158
Pubmed

Expression of aldehyde dehydrogenase family 1, member A3 in glycogen trophoblast cells of the murine placenta.

RARA RARB RXRA RXRB RXRG

2.85e-121634525577283
Pubmed

External genitalia formation: role of fibroblast growth factor, retinoic acid signaling, and distal urethral epithelium.

RARA RARB RXRA RXRB RXRG

2.85e-121634511795391
Pubmed

A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1.

NR4A2 RARA RXRA RXRB

3.80e-1253447705655
Pubmed

Developmental expression of murine retinoid X receptor (RXR) genes.

RARB RXRA RXRB RXRG

3.80e-1253448199055
Pubmed

Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development.

RARA RARB RXRA RXRB

3.80e-1253449053308
Pubmed

Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterning.

RARA RARB RXRA RXRB RXRG

1.01e-112034519605690
Pubmed

TGIF inhibits retinoid signaling.

RARA RXRA RXRB RXRG

1.14e-11634416428452
Pubmed

Nuclear receptors in Leydig cell gene expression and function.

NR4A3 NR2C1 RARA RXRA RXRB

1.71e-112234520375256
Pubmed

Identification of endogenous retinoids, enzymes, binding proteins, and receptors during early postimplantation development in mouse: important role of retinal dehydrogenase type 2 in synthesis of all-trans-retinoic acid.

RARA RARB RXRA RXRB RXRG

1.71e-112234510753524
Pubmed

A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.

NR4A3 NR2C1 RARB HNF4G RXRA RXRB RXRG

2.15e-1111834716971476
Pubmed

Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells.

RARA RARB RXRA RXRB RXRG

2.18e-112334519737349
Pubmed

The structure of the nuclear hormone receptors.

RARB RXRA RXRB RXRG

2.66e-11734410406480
Pubmed

Analysis of the factors involved in the retinoic acid-induced differentiation of a retinoid-hypersensitive embryonal carcinoma cell mutant.

RARB RXRA RXRB RXRG

2.66e-1173448299717
Pubmed

Diverse Functions of Retinoic Acid in Brain Vascular Development.

RARA RARB RXRA RXRB RXRG

6.35e-112834527445154
Pubmed

Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal.

RARA RARB RXRA RXRB RXRG

1.30e-103234517270348
Pubmed

Enhancer activation requires trans-recruitment of a mega transcription factor complex.

RARA RXRA RXRB RXRG

1.59e-101034425303530
Pubmed

Unique response pathways are established by allosteric interactions among nuclear hormone receptors.

NR4A2 RXRA RXRB

8.54e-1033437758108
Pubmed

Cooperative formation of high-order oligomers by retinoid X receptors: an unexpected mode of DNA recognition.

RXRA RXRB RXRG

8.54e-1033437831303
Pubmed

mRNA expression pattern of retinoic acid and retinoid X nuclear receptor subtypes in human thyroid papillary carcinoma.

RARA RARB RXRG

8.54e-10334323969901
Pubmed

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.

RXRA RXRB RXRG

8.54e-1033431312497
Pubmed

Detection of retinoid X receptors using specific monoclonal and polyclonal antibodies.

RXRA RXRB RXRG

8.54e-1033437980510
Pubmed

Immunohistochemical detection of the retinoid X receptors alpha, beta, and gamma in human prostate.

RXRA RXRB RXRG

8.54e-10334312514092
Pubmed

Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects.

RXRA RXRB RXRG

8.54e-10334311053444
Pubmed

Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies.

RARA RARB RXRA

8.54e-10334315528208
Pubmed

Impaired locomotion and dopamine signaling in retinoid receptor mutant mice.

RARB RXRB RXRG

8.54e-1033439452386
Pubmed

Retinoid X receptors: X-ploring their (patho)physiological functions.

RXRA RXRB RXRG

8.54e-10334315608692
Pubmed

Chromosomal localization of the human retinoid X receptors.

RXRA RXRB RXRG

8.54e-1033438034312
Pubmed

Differential expression of retinoic acid receptors in normal and malignant esophageal tissues.

RARA RARB RXRA

8.54e-10334315255287
Pubmed

Retinoid receptors trigger neuritogenesis in retinal degenerations.

RXRA RXRB RXRG

8.54e-10334321940995
Pubmed

The role of retinoid X receptor messenger RNA expression in curatively resected non-small cell lung cancer.

RXRA RXRB RXRG

8.54e-10334311839661
Pubmed

An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression.

RARB RXRB RXRG

8.54e-1033439883728
Pubmed

RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta -/-/RXR gamma -/- mutant mice are viable.

RXRA RXRB RXRG

8.54e-1033438799145
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

NR4A2 NR4A3 NR2C1 RARA RARB FBLIM1 HNF4G RXRA RXRB RXRG

9.82e-10709341022988430
Pubmed

Signaling through retinoic acid receptors is essential for mammalian uterine receptivity and decidualization.

RARA RARB RXRA RXRB RXRG

2.21e-095534534292881
Pubmed

Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently.

RXRA RXRB RXRG

3.41e-0943431310259
Pubmed

Retinoid-dependent antagonism of serum response factor transactivation mediated by transcriptional coactivator proteins.

RARA RXRA RXRG

3.41e-09434311641790
Pubmed

Nuclear GRP75 binds retinoic acid receptors to promote neuronal differentiation of neuroblastoma.

RARA RARB RXRA

3.41e-09434322022577
Pubmed

Pregnane X Receptor Expression in Human Pancreatic Adenocarcinoma: Associations With Clinicopathologic Parameters, Tumor Proliferative Capacity, Patients' Survival, and Retinoid X Receptor Expression.

RXRA RXRB RXRG

3.41e-09434326355550
Pubmed

Retinoids activate RXR/CAR-mediated pathway and induce CYP3A.

RXRA RXRB RXRG

3.41e-09434319686701
Pubmed

Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled.

RARA RARB RXRA

3.41e-09434312093741
Pubmed

Absence of thyroid hormone receptor beta-retinoid X receptor interactions in auditory function and in the pituitary-thyroid axis.

RXRA RXRB RXRG

3.41e-0943439804293
Pubmed

Retina-specific nuclear receptor: A potential regulator of cellular retinaldehyde-binding protein expressed in retinal pigment epithelium and Müller glial cells.

RARA RXRA RXRB

3.41e-09434310611353
Pubmed

Effects of retinoid ligands on RIP140: molecular interaction with retinoid receptors and biological activity.

RARA RXRA RXRB

3.41e-09434312549917
Pubmed

Limited specificity and large overlap of the functions of the mouse RAR gamma 1 and RAR gamma 2 isoforms.

RARA RARB RXRA

3.41e-0943439376317
Pubmed

Dimerization with retinoid X receptors and phosphorylation modulate the retinoic acid-induced degradation of retinoic acid receptors alpha and gamma through the ubiquitin-proteasome pathway.

RARA RARB RXRA

3.41e-09434310869350
Pubmed

An essential set of basic DNA response elements is required for receptor-dependent transcription of the lecithin:retinol acyltransferase (Lrat) gene.

RARA RARB RXRA

8.52e-09534319665987
Pubmed

Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein.

RARB RXRA RXRB

8.52e-0953431331778
Pubmed

Retinoid X receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurr1, and Nor1.

NR4A2 NR4A3 RXRA

8.52e-0953438961274
Pubmed

ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome.

RARA RARB RXRA

8.52e-09534319345331
Pubmed

A census of human transcription factors: function, expression and evolution.

NR4A2 NR4A3 NR2C1 KMT2D RARA RARB HNF4G RXRA RXRB RXRG

1.04e-08908341019274049
Pubmed

Peroxisome proliferator-activated receptors modulate proliferation and angiogenesis in human endometrial carcinoma.

RXRA RXRB RXRG

1.70e-08634322205725
Pubmed

Retinoid signaling and the generation of regional and cellular diversity in the embryonic mouse spinal cord.

RARA RARB RXRG

1.70e-0863438563020
Pubmed

Cloning and expression during development of three murine members of the COUP family of nuclear orphan receptors.

RXRA RXRB RXRG

1.70e-0863437947324
Pubmed

Mesenchymal/epithelial regulation of retinoic acid signaling in the olfactory placode.

RARA RARB RXRG

1.70e-08634312941622
Pubmed

Dissecting the role of retinoic acid receptor isoforms in the CD8 response to infection.

RARA RARB RXRA

2.98e-08734324610012
Pubmed

Isotype-restricted corepressor recruitment: a constitutively closed helix 12 conformation in retinoic acid receptors beta and gamma interferes with corepressor recruitment and prevents transcriptional repression.

RARA RARB RXRA

2.98e-08734312665583
Pubmed

Normal fate and altered function of the cardiac neural crest cell lineage in retinoic acid receptor mutant embryos.

RARA RARB RXRA

2.98e-08734312204252
Pubmed

Age-dependent retinoic acid regulation of gene expression distinguishes the cervical, thoracic, lumbar, and sacral spinal cord regions during development.

RARA RARB RXRG

2.98e-08734310449983
Pubmed

A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors.

RARA RXRA RXRG

4.76e-0883438616895
Pubmed

Retinoid X receptor (gamma) is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina.

RXRA RXRB RXRG

4.76e-08834316043864
Pubmed

Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner.

FLRT2 RARA RARB RXRB

4.91e-083734420236931
Pubmed

Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves.

FLRT2 RARA RARB RXRB

4.91e-083734438011284
Pubmed

TRAM-1, A novel 160-kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator-1.

RARA RXRA RXRB

7.14e-0893439346901
Pubmed

A novel nuclear FGF Receptor-1 partnership with retinoid and Nur receptors during developmental gene programming of embryonic stem cells.

NR4A2 RARA RXRA

7.14e-08934322539306
InteractionRARB interactions

RARA RARB RXRA RXRB RXRG

1.31e-0846345int:RARB
InteractionRARG interactions

RARA RARB RXRA RXRB RXRG

4.32e-0858345int:RARG
InteractionNCOA1 interactions

NR4A2 RARA RARB HNF4G RXRA RXRB

1.48e-07146346int:NCOA1
InteractionNR1H4 interactions

RARA RXRA RXRB RXRG

2.35e-0732344int:NR1H4
InteractionNR0B2 interactions

RARA HNF4G RXRA RXRB RXRG

2.66e-0783345int:NR0B2
InteractionNRIP1 interactions

NR2C1 RARA RARB RXRA RXRB RXRG

3.65e-07170346int:NRIP1
InteractionTGIF1 interactions

RARA RXRA RXRB RXRG

6.54e-0741344int:TGIF1
InteractionRXRG interactions

RARA RARB RXRA RXRG

1.14e-0647344int:RXRG
InteractionRARA interactions

NR2C1 RARA RARB RXRA RXRB RXRG

1.78e-06223346int:RARA
InteractionNR1H3 interactions

RARA RXRA RXRB RXRG

2.69e-0658344int:NR1H3
InteractionRXRB interactions

NR4A2 RARA RARB RXRB

4.52e-0666344int:RXRB
InteractionNR1H2 interactions

RARA RXRA RXRB RXRG

5.09e-0668344int:NR1H2
InteractionNR2E3 interactions

RARA RXRA RXRB

5.72e-0621343int:NR2E3
InteractionRXRA interactions

NR4A2 RARA RARB RXRA RXRG

8.93e-06169345int:RXRA
InteractionPPARG interactions

NR4A2 KMT2D RARA RXRA RXRB RXRG

1.12e-05307346int:PPARG
InteractionNR4A2 interactions

NR4A2 RXRA RXRB

1.25e-0527343int:NR4A2
InteractionNCOA3 interactions

RARA RARB HNF4G RXRA RXRB

3.47e-05224345int:NCOA3
InteractionTHRA interactions

HAL RXRA RXRB RXRG

3.56e-05111344int:THRA
InteractionWNT8B interactions

HAL WNT8B

4.13e-056342int:WNT8B
InteractionTNNI2 interactions

HNF4G ATP2A1 TLE4

4.15e-0540343int:TNNI2
InteractionNR1I2 interactions

RXRA RXRB RXRG

7.20e-0548343int:NR1I2
InteractionNCOR2 interactions

NR4A2 RARA RARB RXRA RXRG

7.57e-05264345int:NCOR2
InteractionTLX2 interactions

NR2C1 KMT2D HAL TLE4

9.30e-05142344int:TLX2
InteractionNCOA6 interactions

KMT2D RARA RXRA RXRG

1.01e-04145344int:NCOA6
InteractionTLX3 interactions

NR2C1 KMT2D HAL HNF4G TLE4

1.20e-04291345int:TLX3
InteractionPSMC5 interactions

FNDC3A RARA RARB GRM2 HNF4G RXRA

1.41e-04484346int:PSMC5
InteractionLHX3 interactions

NR2C1 KMT2D HAL ATP2A1

2.57e-04185344int:LHX3
InteractionKLF5 interactions

NR2C1 KMT2D RARA RXRA

3.14e-04195344int:KLF5
InteractionGADD45G interactions

FAM156A RARA RXRA

3.18e-0479343int:GADD45G
InteractionGATA2 interactions

KMT2D RARA RXRA TLE4

3.39e-04199344int:GATA2
InteractionPPARGC1A interactions

NR4A2 RARB RXRA

3.55e-0482343int:PPARGC1A
InteractionORC5 interactions

ATP2A1 CD80 STAB1

4.22e-0487343int:ORC5
InteractionKCTD16 interactions

HAL OTUD7A

4.64e-0419342int:KCTD16
InteractionPPARA interactions

RXRA RXRB RXRG

4.97e-0492343int:PPARA
InteractionSIX3 interactions

NR4A3 TLE4

5.15e-0420342int:SIX3
InteractionGRIP1 interactions

RARA GRM2 RXRA

5.63e-0496343int:GRIP1
InteractionPNRC1 interactions

RARB HNF4G

6.84e-0423342int:PNRC1
InteractionALOX15B interactions

RARA RXRA

6.84e-0423342int:ALOX15B
InteractionSMARCD3 interactions

RARA RARB RXRA

7.72e-04107343int:SMARCD3
GeneFamilyNuclear hormone receptors

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

2.41e-174928971
GeneFamilyOTU domain containing

OTUD7B OTUD7A

3.10e-0417282669
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SCARF2 STAB1

7.93e-04272821253
GeneFamilyFibronectin type III domain containing

FNDC3B FNDC3A FLRT2

1.89e-03160283555
CoexpressionGSE3920_UNTREATED_VS_IFNA_TREATED_ENDOTHELIAL_CELL_UP

LRP1 FNDC3A FBLIM1 PTGS1 STAB1

2.98e-06175345M6684
CoexpressionFLETCHER_PBMC_BCG_10W_INFANT_BCG_STIMULATED_VS_UNSTIMULATED_10W_DN

LRP1 FLRT2 PTGS1 RXRA STAB1

1.89e-05256345M41152
CoexpressionTAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN

NR4A2 RARA CD80

2.73e-0545343M10084
CoexpressionCASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP

NR4A2 FNDC3B HAL STAB1

7.45e-05174344M2038
CoexpressionFLETCHER_PBMC_BCG_10W_INFANT_PPD_STIMULATED_VS_UNSTIMULATED_10W_DN

LRP1 FLRT2 PTGS1 STAB1

8.68e-05181344M40912
CoexpressionGSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_DN

LRP1 HAL PTGS1 STAB1

9.05e-05183344M7627
CoexpressionGSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP

LRP1 HAL PTGS1 STAB1

9.05e-05183344M7635
CoexpressionGSE11057_CD4_EFF_MEM_VS_PBMC_DN

FNDC3B HAL PTGS1 RXRA

1.13e-04194344M3114
CoexpressionGSE44649_WT_VS_MIR155_KO_NAIVE_CD8_TCELL_UP

LRP1 FBLIM1 ENPP1 RXRA

1.23e-04198344M9778
CoexpressionGSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP

KMT2D HAL RXRB TLE4

1.23e-04198344M7948
CoexpressionGSE42088_UNINF_VS_LEISHMANIA_INF_DC_2H_DN

NR4A2 RARA HAL TLE4

1.28e-04200344M9901
CoexpressionGSE28737_BCL6_HET_VS_BCL6_KO_FOLLICULAR_BCELL_DN

RARA HAL PTGS1 ENPP1

1.28e-04200344M9385
CoexpressionAtlasMyeloid Cells, MF.Thio5.II-480hi.PC, CD115+ MHC II- F480hi Siglec F-, Peritoneal Cavity, avg-3

LRP1 FNDC3B HAL RARB FBLIM1 CD80 PTGS1 ENPP1

3.67e-07441348GSM605862_500
CoexpressionAtlasMyeloid Cells, DC.11cloSer.Salm3.SI, CD45+ MHCII+ Gr1- CD11c-lo CD11b+, Small Intestine, avg-4

NR4A2 LRP1 NR4A3 CD80 PTGS1 STAB1

2.18e-05364346GSM854276_500
CoexpressionAtlasMyeloid Cells, DC.103-11b+.Lv, CD45+ CD11c+ MHC-II + CD11b high CD103-, Liver, avg-3

NR4A2 LRP1 NR4A3 CD80 PTGS1 STAB1

4.31e-05411346GSM538239_500
CoexpressionAtlasMyeloid Cells, DC.103-11b+24-.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24-, Lung, avg-2

NR4A2 LRP1 FNDC3B NR4A3 CD80 STAB1

4.49e-05414346GSM854271_500
CoexpressionAtlasMyeloid Cells, DC.II+480lo.PC, F4/80lo MHC II+ CD11c+ CD115+, Peritoneal Cavity, avg-3

LRP1 FNDC3B HAL RARB CD80 PTGS1

5.12e-05424346GSM854294_500
CoexpressionAtlasMyeloid Cells, MF.Thio5.II+480int.PC, CD115+ MHC II+ F480lo SiglecF- CD11c+, Peritoneal Cavity, avg-3

LRP1 FNDC3B HAL PTGS1 ENPP1 STAB1

5.76e-05433346GSM605856_500
CoexpressionAtlasMyeloid Cells, MF.Thio5.II-480int.PC, CD115+ MHCII- F480int SiglecF- CD11c+, Peritoneal Cavity, avg-3

LRP1 FNDC3B HAL PTGS1 ENPP1 STAB1

6.06e-05437346GSM605865_500
CoexpressionAtlasMyeloid Cells, MF.II-480hi.PC, F4/80hi CD115hi CD11b+ MHC II- CD11c-, Peritoneal Cavity, avg-3

LRP1 FNDC3B HAL RARB CD80 PTGS1

6.13e-05438346GSM605850_500
CoexpressionAtlasMyeloid Cells, DC.103+11b+.SI, CD45+ MHCII+ CD11c-hi CD11b+ CD103+ F4/80-lo, Small Intestine, avg-4

NR4A2 NR4A3 CD80

1.09e-0458343GSM854237_100
CoexpressionAtlasMyeloid Cells, DC.103+11b+.Salm3.SI, CD45+ MHCII+ Gr1- CD11c-hi CD11b+ CD103+ F480-, Small Intestine, avg-5

NR4A2 NR4A3 CD80

1.83e-0469343GSM854232_100
CoexpressionAtlasMyeloid Cells, DC.103-11b+.Salm3.SI, CD45+ MHCII+ Gr1- CD11c-hi CD11b+ CD103- F480+, Small Intestine, avg-4

LRP1 NR4A3 CD80 PTGS1 STAB1

2.80e-04368345GSM854258_500
CoexpressionAtlasMyeloid Cells, DC.103+11b-.PolyIC.Lu, CD45 MHCII CD11c CD103 CD11b, Lung, avg-3

NR4A2 LRP1 NR4A3 FNDC3A CD80

3.40e-04384345GSM605820_500
CoexpressionAtlasMyeloid Cells, MF.II-480hi.PC, F4/80hi CD115hi CD11b+ MHC II- CD11c-, Peritoneal Cavity, avg-3

LRP1 HAL PTGS1

3.51e-0486343GSM605850_100
CoexpressionAtlasdev gonad_e11.5_M_ReproVasc_Flk_k-means-cluster#2_top-relative-expression-ranked_1000

NR4A2 FLRT2 RARB

3.75e-0488343gudmap_dev gonad_e11.5_M_ReproVasc_Flk_k2_1000
CoexpressionAtlasEctoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05

FAM156A NR2C1 FNDC3A CELSR1 RARA RARB RXRB TLE4 WNT8B

3.76e-041466349PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlasdev gonad_e11.5_F_ReproVasc_Flk_top-relative-expression-ranked_500

NR4A2 FLRT2 RARB PTGS1 STAB1

4.54e-04409345gudmap_dev gonad_e11.5_F_ReproVasc_Flk_500
CoexpressionAtlasMyeloid Cells, MF.Thio5.II+480lo.PC, CD115+ MHC II+ F480lo SiglecF- CD11c+, Peritoneal Cavity, avg-3

LRP1 FNDC3B HAL RARB PTGS1

5.47e-04426345GSM605859_500
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

LRP1 FNDC3B FLRT2 TNMD OTUD7B

6.14e-04437345GSM777046_500
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NR4A2 LRP1 NR4A3 VPS18 STAB1

1.90e-071713455e93c76ee60f9d0590ebb140812653a5e1369417
ToppCellBAL-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NR4A2 NR4A3 CD80 PTGS1 ENPP1

3.84e-071973456f83fc049f38f3de6bc5180ad4b51ceb4d5dcdb6
ToppCellControl-Myeloid-cDC|Control / Disease group,lineage and cell class (2021.01.30)

NR4A2 NR4A3 CD80 PTGS1 ENPP1

3.84e-07197345aef933107da42a763b35041c90950db07707c0cb
ToppCellBAL-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

NR4A2 NR4A3 CD80 PTGS1 ENPP1

3.84e-0719734515e683f4a610aad3e06723747c8e56ca25f57414
ToppCellBAL-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NR4A2 NR4A3 CD80 PTGS1 ENPP1

3.84e-071973456ac50c02899531a25885749d5305da788dfa9dbc
ToppCellBAL-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

NR4A2 NR4A3 CD80 PTGS1 ENPP1

3.84e-07197345513ada82bbbb6a624d89edaa54f8c4a303dfb5e7
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBLIM1 RXRA STAB1

6.57e-061603440544bc465af208da448858d6e174ff56f2e08a46
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NR4A2 NR4A3 FLRT2 TECTA

7.07e-061633441e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-CD1c+_DCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

NR4A2 NR4A3 CD80 PTGS1

8.35e-06170344403b6b749d70d845838dcda7daf99971b50792a2
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

NR4A3 PTGS1 RXRA STAB1

8.75e-06172344f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-monocytoid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

NR4A2 NR4A3 CD80 STAB1

9.79e-06177344945b2d0723a0a35c767604ae607d2c2d53bf0c82
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NR4A2 NR4A3 CD80 STAB1

1.02e-0517934442f3c040f504a91cc69292d39d22b5715c12526f
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NR4A2 NR4A3 CD80 STAB1

1.02e-05179344063c05753ef1b4a18bc1ebbcae62c8cd25d11070
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NR4A2 NR4A3 RXRA STAB1

1.05e-051803446f8fa9fa91cd25b92584972bb34d90c483222f52
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR4A3 CELSR1 PTGS1 STAB1

1.12e-051833446c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCCHC4 CELSR1 PTGS1 STAB1

1.12e-05183344b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRP1 FLRT2 RXRA STAB1

1.19e-0518634423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellfacs-Heart-LA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 FLRT2 PTGS1 STAB1

1.22e-051873447b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCellfacs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 FLRT2 PTGS1 STAB1

1.22e-05187344d9943e65eedab73d141eae524e2411653a751705
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 FLRT2 PTGS1 STAB1

1.27e-051893441137583e21d874c201c20581ba1995e2bfa3de59
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CELSR1 FLRT2 RARB STAB1

1.29e-05190344a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 FLRT2 PTGS1 STAB1

1.29e-051903447068754c29f63a331e2b6c54715f3b26f37ad32b
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CELSR1 FLRT2 RARB STAB1

1.29e-0519034457c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CELSR1 FLRT2 RARB STAB1

1.29e-05190344f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR4A3 CELSR1 PTGS1 STAB1

1.29e-051903446f71a9f74af7cd9a674753cfc9833ebe5bba0fa2
ToppCell(3)_MNP-(3)_DC_2|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

NR4A2 NR4A3 CD80 PTGS1

1.32e-051913443ff163484af8c12ef4eef87246cf044257fd2547
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FLRT2 FBLIM1 ENPP1

1.35e-05192344bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell367C-Myeloid-Dendritic|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NR4A2 NR4A3 CD80 ENPP1

1.35e-05192344877aaf61d8fc40e7013944a0180306dd0bb0557f
ToppCell356C-Myeloid-Dendritic-cDC2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NR4A2 NR4A3 CD80 PTGS1

1.35e-05192344a7ccbea7c90c070d279d7ad3f2b5b7c0e3efd890
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 FLRT2 PTGS1 STAB1

1.35e-0519234414a816ef116aa992f86edab411f043cf7d07fe04
ToppCellfacs-Heart-LA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 FLRT2 PTGS1 STAB1

1.35e-05192344847822514d747a21d5eb40e04ba9a023fd32bd65
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FLRT2 FBLIM1 ENPP1

1.35e-051923440ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Neutrophils|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

NR4A2 NR4A3 TLE4 STAB1

1.40e-0519434428571cf24b8a1d0ffb716167b977d420868cc874
ToppCell343B-Myeloid-Dendritic-cDC2|343B / Donor, Lineage, Cell class and subclass (all cells)

NR4A2 NR4A3 CD80 PTGS1

1.40e-05194344aa6c9b71006fd3863a802d112d9c3838865a52bf
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NR4A2 FNDC3B NR4A3 STAB1

1.40e-05194344449ce4167d64c170d914e0250f739eabedcf915d
ToppCellControl-Classical_Monocyte-cMono_2|Control / Disease condition and Cell class

NR4A2 LRP1 RXRA STAB1

1.43e-051953440fea64ee3eedf3929abb0dd9c5f5fc72f181eed9
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NR4A2 NR4A3 CD80 PTGS1

1.43e-051953449cfbdb528088ad0ab100c7431c7d8f140a846de8
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NR4A3 CD80 PTGS1 STAB1

1.43e-05195344c9469e2d31beb30ebb64b3f0a5239e23119fbaa5
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NR4A2 NR4A3 CD80 PTGS1

1.43e-0519534466f3b3e15eaa21bc7cf2f204cac81de1a160a748
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NR4A3 CD80 PTGS1 STAB1

1.43e-051953442f2e29089a8cb748d2c1329c5c8465165b25bc8b
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NR4A2 NR4A3 CD80 PTGS1

1.43e-05195344bbf5f79be4fcea754328f1af7ee5625075248100
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 FLRT2 PTGS1 STAB1

1.46e-051963447d5eaed189aa6116f3799be010139fb675ec65e0
ToppCell10x5'-Lung-Myeloid_Mac-Intermediate_macrophages|Lung / Manually curated celltypes from each tissue

NR4A2 FNDC3B NR4A3 STAB1

1.46e-05196344fede2c605f7581ce2ea7a284cffffa1a3970d811
ToppCellfacs-Trachea|facs / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR4A2 LRP1 FNDC3B NR4A3

1.46e-0519634434020d6553309daa269dff05de0a8567211ea4d2
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 FLRT2 PTGS1 STAB1

1.46e-05196344e386526332138e636aef2542c11316347a45689c
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR4A2 LRP1 TNMD SCARF2

1.46e-0519634461bee32ca299219f31a30b57124e44e85b798e9f
ToppCellControl-Myeloid-DC2|Control / Condition, Lineage and Cell class

NR4A2 NR4A3 CD80 PTGS1

1.46e-051963440ccc26c2811e4c8631e0abd8555b167ac1e7a982
ToppCellfacs-Trachea|facs / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NR4A2 LRP1 FNDC3B NR4A3

1.46e-051963448209f2b0f7efebaaf81d642d18a1aee8a9a8dcf6
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 FLRT2 PTGS1 STAB1

1.46e-05196344dbf154b3d166ffd07be717dac8d8a3350ac63e16
ToppCellcontrol-Myeloid-Non-resident_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

LRP1 FNDC3B RXRA STAB1

1.49e-05197344df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCellControl-Myeloid-DC2|Myeloid / Condition, Lineage and Cell class

NR4A2 NR4A3 CD80 PTGS1

1.49e-05197344e0ee15188ff0d9df3c3b5ea523553ce18d223c33
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FLRT2 FBLIM1 ENPP1

1.49e-05197344ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FLRT2 FBLIM1 ENPP1

1.49e-0519734437f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellnormal_Lung-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

NR4A2 NR4A3 PTGS1 STAB1

1.52e-05198344fbd72ebaba73cc30e79dc8a8c3d46b6f863c1494
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FNDC3B TNMD SCARF2

1.52e-051983441b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCellSkin-Mesangial|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

FAM156A TECTA HNF4G WNT8B

1.55e-05199344bcb78838a91cc7828680fb413fbacdb091c5fac0
ToppCellBronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NR4A2 NR4A3 CD80 PTGS1

1.55e-05199344fdd8c4c04837341e17a4772a2adcdf2f187c56b1
ToppCellBiopsy_Other_PF-Immune-cDCs|Biopsy_Other_PF / Sample group, Lineage and Cell type

NR4A2 NR4A3 CD80 PTGS1

1.58e-052003448e455f685f0a9c63e83d6d339d7767f0e9841c6e
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rxfp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NR4A2 TNMD TLE4

1.35e-0413134381efe8b0ca4377e557a42ddb12aecaf3f46b15bf
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rprm|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TNMD RXRG TLE4

1.38e-0413234366ec5a06eece27c0aafb548f51db9fee595e71bc
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Eya1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RARB PTGS1 RXRG

1.44e-04134343657ad905b40ec3f82acdef824431b8276d291ef7
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

FNDC3A KMT2D TECTA

1.48e-04135343ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Blood_Derived_Cancer_-_Peripheral_Blood-Leukemia-Acute_Myeloid_Leukemia-3|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

LRP1 RARA RXRA

1.51e-041363434f5e0b6c7d6e3e922af4daa7c3eb56490455c1df
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Crh|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NR4A2 TNMD TLE4

1.51e-0413634344f03e4f55fb2c5f8b9397142c89f7194b009cc6
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3|Hippocampus / BrainAtlas - Mouse McCarroll V32

NR4A2 RXRG TLE4

1.58e-04138343b63e26afafbd2cdeed9c9451e6f530ab6295504c
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NR4A2 RARB RXRG

1.64e-041403432c44e8cc5190226049be7ebc465d685393e701c4
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NR4A2 TNMD TLE4

1.68e-041413435ef3166c5271aa90fd0633016edfe2c74b835319
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SCARF2 PTGS1

1.71e-04142343a05b320cf182b2aaf18df7c40045dc65b659bf20
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 SCARF2 PTGS1

1.71e-04142343d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NR4A2 NR4A3 STAB1

1.75e-041433437adc34d8ad11e57950a5a258ae9bf8f52259385a
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KMT2D TECTA HNF4G

1.75e-0414334392ddc3e3f6ba78dd9daeb272c12503ec2650a874
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD80 PTGS1 STAB1

1.82e-04145343778655fffd73df101e656154a41b478a1b695116
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RARB PTGS1 RXRG

2.05e-04151343090b067873740c282865e2d02cf47d5cb3dd7607
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NR4A3 KMT2D ENPP1

2.09e-041523430652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR4A2 NR4A3 CELSR1

2.30e-04157343ad8c6eb34f5288288c4066119c17325afefbaafc
ToppCellCOPD-Myeloid-DC_Langerhans|COPD / Disease state, Lineage and Cell class

NR4A3 FLRT2 CD80

2.35e-0415834371af1319eec34bf7bc9361ec9ef720c280ce97d1
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

NR4A2 HAL SCARF2

2.39e-04159343af137688e06a97ff97bb7def54f0dd164d155b11
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FNDC3B FBLIM1

2.44e-04160343bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FNDC3B FBLIM1

2.44e-0416034356e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_8|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NR4A2 NR4A3 CD80

2.48e-041613437e0b8119cea208c0b4a0dffdf94ff6137d0b4c90
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR4A2 FNDC3B FLRT2

2.48e-04161343334f540dff3508d451e5e85e8e4e8f3b8d6b74e7
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELSR1 FLRT2 STAB1

2.48e-04161343133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELSR1 FLRT2 STAB1

2.48e-04161343cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR4A2 FNDC3B FLRT2

2.48e-0416134381d44438e4be4e68a59247e62f02026301a8a0c5
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELSR1 FLRT2 STAB1

2.48e-041613439466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NR4A3 CD80 ENPP1

2.48e-04161343cd41abb7ae659d3d314281783a0aaad562b26037
ToppCellVE-mono3|VE / Condition, Cell_class and T cell subcluster

NR4A2 NR4A3 PTGS1

2.48e-041613437df3fefc55ab43b897fc78d1f0c7383b10ac33d5
ToppCellVE-mono3-|VE / Condition, Cell_class and T cell subcluster

NR4A2 NR4A3 PTGS1

2.48e-041613434e45bf7eceb0ee30dec4d8852778366776ea5a8f
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FNDC3B FBLIM1

2.48e-0416134360f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_8|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NR4A2 NR4A3 CD80

2.53e-041623432fd6e8f48b48d509a7533cec2f79089513c34a2f
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELSR1 FLRT2 STAB1

2.53e-0416234396c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCellnormal_Lymph_Node-Myeloid_cells-Monocytes|Myeloid_cells / Location, Cell class and cell subclass

NR4A2 NR4A3 TLE4

2.57e-041633437d7f18e5c99be125e95bc180823430291b770d05
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 FBLIM1 CD80

2.57e-04163343f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ATP2A1 SCARF2 CD80

2.57e-041633439f5facfa1864eb63e2f8022ad7379d9252b7a254
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NR4A3 CD80 ENPP1

2.62e-041643433a4ecc632be003d09b765c992804134348d2278b
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NR4A3 CD80 ENPP1

2.62e-041643434b10b78d4d76023c3c5bcd427757218fdd5465ca
ToppCellnormal_Lymph_Node-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

NR4A2 NR4A3 PTGS1

2.71e-04166343d638d356592325cded4a6cb549041cf2f8d3e62c
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TECTA RXRA STAB1

2.71e-0416634328a44448a0b0d72459e8fe84ce5d666f16f514b3
ToppCellnormal_Lung-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

NR4A2 NR4A3 PTGS1

2.71e-0416634307b498eb341abec02a3ccaae320bdbb5cd6883c5
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TECTA RXRA STAB1

2.71e-041663432a04915d534a83e65aa168435d6856125b5bdd78
ComputationalGenes in the cancer module 27.

NR4A2 LRP1 RARA RARB GRM2 CD80 RXRA

1.54e-05355267MODULE_27
ComputationalSteroid hormone receptors and binding proteins.

HNF4G RXRA RXRG

3.15e-0526263MODULE_404
ComputationalGenes in the cancer module 257.

LRP1 KMT2D RARA TLE4

4.98e-04156264MODULE_257
DrugHX 630

RARA RARB CD80 RXRA RXRB RXRG

1.45e-1510346ctd:C422175
DrugAlitretinoin

RARA RARB RXRA RXRB RXRG

3.27e-146345DB00523
DrugAdapalene

RARA RARB RXRA RXRB RXRG

3.27e-146345DB00210
DrugEtretinate

RARA RARB RXRA RXRB RXRG

3.27e-146345DB00926
DrugAcitretin

RARA RARB RXRA RXRB RXRG

1.14e-137345DB00459
DrugHX600

NR4A2 RARA RARB RXRA RXRB RXRG

1.28e-1318346CID000128016
DrugHX 600

RARA RARB RXRA RXRB RXRG

3.05e-138345ctd:C104181
DrugTTNN

RARA RARB RXRA RXRB RXRG

3.05e-138345CID000135754
Drugadapalene

RARA RARB PTGS1 RXRA RXRB RXRG

5.10e-1322346CID000060164
DrugAC1L2X6Z

RARA RARB CD80 RXRA RXRB RXRG

2.01e-1227346CID000130325
DrugUVI 3003

RARA RARB RXRA RXRB RXRG

2.51e-1211345ctd:C525131
DrugCd2665

RARA RARB RXRA RXRB RXRG

6.97e-1213345CID000216241
DrugAC1L1DMQ

RARA RARB RXRA RXRB RXRG

1.08e-1114345CID000002418
Drugtazarotene

RARA RARB PTGS1 RXRA RXRB RXRG

2.58e-1140346CID000005381
DrugRo 15-0778

RARA RARB RXRA RXRB RXRG

1.80e-1023345CID006436116
DrugAC1O5JP6

RARA RXRA RXRB RXRG

2.89e-108344CID006435379
DrugAC1L2E0P

NR4A2 NR4A3 NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

5.11e-10307349CID000019390
DrugAGN 193109

RARA RARB RXRA RXRB RXRG

9.02e-1031345CID000177238
DrugCD367

RARA RARB RXRA RXRB RXRG

1.26e-0933345CID000119342
DrugDR-0

RARA HNF4G RXRA RXRB RXRG

1.72e-0935345CID010062716
DrugA-74702

NR2C1 RARA RARB RXRA RXRB RXRG

1.93e-0980346CID000452307
DrugRo 41-5253

RARA RARB RXRA RXRB RXRG

2.30e-0937345CID005312120
Drugtazarotenic acid

RARB RXRA RXRB RXRG

2.93e-0913344CID000147525
Drugtamibarotene

RARA RARB SCARF2 RXRA RXRB RXRG

3.01e-0986346CID000108143
DrugBexarotene

RXRA RXRB RXRG

3.04e-093343DB00307
Drug2-hydroxyphytanic acid

RXRA RXRB RXRG

3.04e-093343ctd:C002585
DrugAC1O5SBP

RXRA RXRB RXRG

3.04e-093343CID006439746
Drugvitamin D3 analog

RARA RARB RXRA RXRB RXRG

3.94e-0941345CID006438384
DrugEtretinate-d3

RARA RARB RXRA RXRB RXRG

6.39e-0945345CID000003312
DrugS-(+)-Methoprene

FNDC3A RARA RXRA RXRB RXRG

7.17e-0946345CID000038532
DrugAGN 190727

RXRA RXRB RXRG

1.22e-084343CID006439768
DrugTazarotene

RARA RARB RXRB

1.22e-084343DB00799
Drugepicholesterol

LRP1 NR2C1 HAL HNF4G ATP2A1 SCARF2 PTGS1 RXRA RXRB RXRG

1.93e-086363410CID000000304
DrugAC1Q6CTU

NR4A2 NR2C1 VPS18 RXRA RXRB RXRG

2.04e-08118346CID000021362
Drugdiheptyl phthalate

NR4A2 RXRA RXRB RXRG

2.44e-0821344ctd:C089799
DrugCV-1

NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

2.47e-08213347CID000130105
DrugBetamethasone-d5

LRP1 NR2C1 FNDC3A RARA RARB HNF4G SCARF2 PTGS1 ENPP1 RXRA RXRB RXRG STAB1

2.78e-0813403413CID000003003
Drug7-methoxycitronellal

RXRA RXRB RXRG

3.04e-085343CID000019223
Drug7-methoxycitronellic acid

RXRA RXRB RXRG

3.04e-085343CID000171516
Drug13,14-dihydroretinol

RXRA RXRB RXRG

3.04e-085343CID000446798
DrugAC1L9M5J

NR4A2 RARA RARB RXRA RXRB RXRG WNT8B

3.18e-08221347CID000448615
Drugretinamide

RARA RARB RXRA RXRB RXRG

5.73e-0869345CID005370221
DrugPrt-H

NR2C1 RXRA RXRB RXRG

6.05e-0826344CID003050291
Drugtriphenyltin hydroxide

RXRA RXRB RXRG

6.07e-086343ctd:C007567
Drug9-cis-acitretin

RARA RARB RXRA RXRB RXRG

6.63e-0871345CID000041317
DrugAGN 191659

RXRA RXRB RXRG

1.06e-077343CID006366726
DrugAGN 190121

RXRA RXRB RXRG

1.06e-077343CID006441236
DrugAC1L1KPQ

RARA RARB RXRA RXRB RXRG

1.07e-0778345CID000005602
Drugsodium cholate

LRP1 HNF4G SCARF2 PTGS1 ENPP1 RXRA RXRB RXRG

1.20e-07408348CID000000303
Drugvitamin D3

LRP1 RARA RARB ATP2A1 RXRA RXRB RXRG

1.49e-07277347CID000002735
DrugRetinoids

RARA RXRA RXRB RXRG

1.86e-0734344ctd:D012176
Drugecdysone

NR4A2 NR2C1 VPS18 RXRA RXRB RXRG

2.35e-07178346CID000019212
Drugretinyl methyl ether

RARA RARB RXRG

2.54e-079343CID006436634
Drugalitretinoin

RARA RARB CD80 PTGS1 RXRA RXRB RXRG

2.61e-07301347ctd:C103303
Drugeq N

RARA RARB RXRA RXRB RXRG

2.73e-0794345CID000002126
Drug3,5-di-tert-butylchalcone 4'-carboxylic acid

RARB CD80 RXRA

3.62e-0710343ctd:C054189
Drugdiazepinylbenzoic acid

RXRA RXRB RXRG

3.62e-0710343ctd:C438269
Drugacyclic retinoid

RARB RXRA RXRB RXRG

4.04e-0741344CID006437836
DrugMethiazole; Up 200; 15uM; MCF7; HT_HG-U133A

NR4A2 ZCCHC4 RARA RARB CD80 PTGS1

4.53e-071993463878_UP
DrugAGN 191701

RXRA RXRB RXRG

4.98e-0711343CID006438168
DrugMusk T

RXRA RXRB RXRG

4.98e-0711343CID000061014
Drugtris

NR2C1 RARA HAL RXRA RXRB RXRG

6.04e-07209346CID000006503
Drugdi-n-propylphthalate

RXRA RXRB RXRG

6.63e-0712343ctd:C106479
DrugNSC46155

RXRA RXRB RXRG

6.63e-0712343CID000457869
Drug9-cis-retinol

NR2C1 RARA RARB HNF4G RXRA RXRB RXRG

8.21e-07357347CID000001071
Drugtroglitazone

LRP1 FNDC3A SCARF2 PTGS1 ENPP1 RXRA RXRB RXRG

8.23e-07526348CID000005591
Drugbenzoate

NR4A3 RARA RARB RXRA RXRB RXRG

8.37e-07221346CID000000242
DrugGW2331

RXRA RXRB RXRG

8.61e-0713343CID000657048
DrugDB04680

NR2C1 RARB CD80 RXRA RXRB RXRG

9.30e-07225346CID005326972
Drugdi-n-pentyl phthalate

NR4A3 RXRA RXRB RXRG

9.85e-0751344ctd:C034171
DrugAC1L9K70

NR2C1 RARA RARB RXRA RXRB RXRG

1.00e-06228346CID000446871
DrugSulfonamides

RXRA RXRB RXRG

1.10e-0614343ctd:D013449
DrugAC1L1JB6

RARB PTGS1 RXRA RXRB RXRG

1.42e-06131345CID000004961
DrugFenretinide

RARA RARB PTGS1 RXRA RXRB RXRG

1.76e-06251346ctd:D017313
Drugphthalic acid

RXRA RXRB RXRG

2.04e-0617343ctd:C032279
Drug9-HODE

GRM2 PTGS1 RXRA RXRB RXRG

2.11e-06142345CID000001927
DrugRo 8-8717

RARA RARB

2.16e-062342CID006438148
DrugTamibarotene

RARA RARB

2.16e-062342DB04942
Drug3,4-didehydroretinoic acid

RARA RARB RXRG

2.44e-0618343CID000447276
Drugretinol palmitate

RARA RXRA RXRG

2.44e-0618343ctd:C014794
Drugandrost-2-en-3-ol

RXRA RXRB RXRG

2.44e-0618343CID000166036
DrugAC1L1C56

RARA RARB PTGS1 RXRA RXRB RXRG

2.79e-06272346CID000001744
Drugponasterone A

GRM2 RXRA RXRB RXRG

3.54e-0670344CID000115127
DrugAC1L1JIR

RARA RARB RXRB RXRG

3.97e-0672344CID000005058
DrugGW9662

RARB CD80 PTGS1 RXRA RXRG

4.16e-06163345CID000644213
Drugdi-n-hexyl phthalate

RXRA RXRB RXRG

4.60e-0622343ctd:C027387
Druggeldanamycin; Up 200; 1uM; HL60; HT_HG-U133A

NR4A2 LRP1 NR4A3 CELSR1 FLRT2

4.68e-061673456187_UP
Drugciglitazone

SCARF2 PTGS1 RXRA RXRB RXRG

4.96e-06169345CID000002750
DrugGriseofulvin

RARA RARB RXRA RXRG

5.19e-0677344ctd:D006118
DrugAC1L32JQ

RARA RARB RXRG

5.28e-0623343CID000133319
DrugT0901317

LRP1 RXRA RXRB RXRG

6.36e-0681344CID000447912
DrugEtodolac

PTGS1 RXRA

6.49e-063342DB00749
Drugscoparone

RXRA RXRB RXRG

6.84e-0625343CID000008417
DrugRitodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; HL60; HT_HG-U133A

NR4A2 NR4A3 FLRT2 PTGS1 TLE4

7.12e-061823451280_UP
Drug11-cis-retinal

RARA RARB RXRA RXRB RXRG

8.56e-06189345CID000001070
DrugNorcyclobenzaprine [303-50-4]; Up 200; 15.4uM; PC3; HT_HG-U133A

NR4A2 LRP1 FLRT2 RARA TLE4

9.00e-061913454190_UP
Drugrhod-2

GRM2 ATP2A1 PTGS1

9.72e-0628343CID000123669
Drugtrifluoperazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A

NR4A3 RARA RARB ENPP1 STAB1

9.95e-061953456183_UP
DrugCGX 0596987; Up 200; 20uM; MCF7; HT_HG-U133A

FNDC3A HAL RARB GRM2 STAB1

1.02e-051963456364_UP
DrugMethimazole [60-56-0]; Up 200; 35uM; PC3; HT_HG-U133A

KMT2D HAL GRM2 ATP2A1 STAB1

1.05e-051973453815_UP
DiseaseNeuralgia-Neuritis, Sciatic Nerve

RARA RARB RXRA

4.63e-094323C0751924
DiseaseSciatic Nerve Palsy

RARA RARB RXRA

4.63e-094323C0751925
DiseaseLesion of Sciatic Nerve

RARA RARB RXRA

4.63e-094323C0154748
DiseaseSciatic Neuritis

RARA RARB RXRA

4.63e-094323C0242013
DiseaseSciatic Neuropathy

RARA RARB RXRA

4.63e-094323C0149940
Diseaseprostate carcinoma in situ (biomarker_via_orthology)

LRP1 RXRA

6.83e-064322DOID:8634 (biomarker_via_orthology)
DiseasePhyllodes Tumor

KMT2D RARA

1.14e-055322C0010701
DiseaseMalignant Cystosarcoma Phyllodes

KMT2D RARA

1.14e-055322C0600066
DiseaseMalignant neoplasm of breast

FNDC3B KMT2D RARA RARB TECTA SCARF2 PTGS1 RXRB

1.45e-051074328C0006142
Diseaseage at menarche

NR4A2 FNDC3B FNDC3A GRM2 HNF4G RXRG

3.77e-05594326EFO_0004703
DiseaseColorectal Carcinoma

NR4A2 LRP1 VPS18 RARB KDF1 WNT8B

9.49e-05702326C0009402
DiseaseMammary Neoplasms, Human

KMT2D RARA RARB PTGS1 RXRB

2.37e-04525325C1257931
DiseaseMammary Carcinoma, Human

KMT2D RARA RARB PTGS1 RXRB

2.37e-04525325C4704874
DiseaseMammary Neoplasms

KMT2D RARA RARB PTGS1 RXRB

2.41e-04527325C1458155
DiseaseBreast Carcinoma

KMT2D RARA RARB PTGS1 RXRB

2.65e-04538325C0678222
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Positive

NR4A2 NR4A3 STAB1

3.86e-04131323C4704862
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Negative

NR4A2 NR4A3 STAB1

3.86e-04131323C4552091
DiseaseJuvenile arthritis

NR4A2 NR4A3 STAB1

3.86e-04131323C3495559
DiseaseJuvenile psoriatic arthritis

NR4A2 NR4A3 STAB1

3.86e-04131323C3714758
DiseaseJuvenile-Onset Still Disease

NR4A2 NR4A3 STAB1

4.22e-04135323C0087031
Diseaselung small cell carcinoma (is_implicated_in)

KMT2D RARB

4.23e-0428322DOID:5409 (is_implicated_in)
Diseaselung non-small cell carcinoma (is_implicated_in)

KMT2D RARB RXRG

4.59e-04139323DOID:3908 (is_implicated_in)
DiseaseEndometrioma

NR2C1 RARB ENPP1

7.04e-04161323C0269102
DiseaseEndometriosis

NR2C1 RARB ENPP1

7.04e-04161323C0014175
Diseaseglioblastoma (is_marker_for)

PTGS1 ENPP1

1.05e-0344322DOID:3068 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
QRFRCSFRQRDCAAH

GRM2

351

Q14416
CAARRNFCDGRRCQN

CELSR1

1646

Q9NYQ6
CCLTYCFAPRCRERR

CD80

261

P33681
RCDRNFVYCNERSLT

FLRT2

41

O43155
QREACRRACCFARVE

ATP2A1

666

O14983
HRNRCQYCRLQRCIA

NR2C1

161

P13056
TRNRCQYCRLQKCFE

RARA

136

P10276
TRNRCQYCRLQKCFE

RARB

136

P10826
NNFCSCCYREELRRR

OTUD7B

816

Q6GQQ9
LGDRSQNRFRCECRY

FAM156A

116

Q8NDB6
QNRFRCECRYCQSHR

FAM156A

121

Q8NDB6
RQCRCTAYFEGSRCE

LRP1

4326

Q07954
RCFERTFGNCRCDAA

ENPP1

111

P22413
VQRRCQRENCAFYGR

OTUD7A

886

Q8TE49
CVRFGLDRYQCDCTR

PTGS1

46

P23219
RNQCRYCRLRKCFRA

HNF4G

61

Q14541
RFCDRVQDAYTLRCC

HAL

386

P42357
NCEYRFRVCAIRQCQ

FNDC3A

1111

Q9Y2H6
YRFRVCACRRCLDTS

FNDC3B

1121

Q53EP0
RNFHENCYRCEDCRI

FBLIM1

326

Q8WUP2
DCLIDKRQRNRCQYC

RXRA

176

P19793
RRNRCQYCRFQKCLA

NR4A2

311

P43354
RNRCQYCRFQKCLSV

NR4A3

341

Q92570
CRAAFCFRRCRDCLQ

KDF1

86

Q8NAX2
DCTVDKRQRNRCQYC

RXRB

246

P28702
WNSDCTRRCRCFRRN

TECTA

1441

O75443
CIYCRRGNRYCRRVC

TNMD

266

Q9H2S6
CEQCRRRVTKYFCSR

WNT8B

321

Q93098
QLDCLNRDNYIRSCR

TLE4

526

Q04727
CRERTFGARCDRYCQ

SCARF2

231

Q96GP6
FGARCDRYCQCFRGR

SCARF2

236

Q96GP6
DFCFRQRRYLESARC

VPS18

431

Q9P253
CLIDKRQRNRCQYCR

RXRG

181

P48443
RQRNRCQYCRYQKCL

RXRG

186

P48443
DAYCFRVQDVACRCR

STAB1

2296

Q9NY15
EETRRFYACSACRDR

ZCCHC4

56

Q9H5U6
YWSLRTNNRRCCYRC

KMT2D

5216

O14686