Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH6 KIF15 KIF16B DNAH2 DYNC1H1 KIF1C

9.10e-06118826GO:0003774
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF15 KIF16B DNAH2 DYNC1H1 KIF1C

1.01e-0570825GO:0003777
GeneOntologyMolecularFunctionrecombination hotspot binding

PRDM9 PRDM7

1.67e-052822GO:0010844
GeneOntologyMolecularFunctionplus-end-directed microtubule motor activity

KIF15 KIF16B KIF1C

4.35e-0517823GO:0008574
GeneOntologyMolecularFunction1-phosphatidylinositol-5-phosphate 4-kinase activity

PIP4K2A PIP4K2B

4.98e-053822GO:0016309
GeneOntologyMolecularFunctioncalcium ion binding

CLEC4E HSP90B1 CPNE6 DST CADPS SPTAN1 AOAH PLA2G4A AIF1L PKDREJ MELK PCDH7

5.29e-057498212GO:0005509
GeneOntologyMolecularFunctionactin filament binding

MYH6 LRPPRC IQGAP2 SPTAN1 AIF1L IQGAP3

3.44e-04227826GO:0051015
GeneOntologyMolecularFunctiontubulin binding

LRPPRC DST KIF15 BRCA2 IFT81 KIF16B FMN2 KIF1C

3.72e-04428828GO:0015631
GeneOntologyMolecularFunctionATP hydrolysis activity

HSP90B1 KIF15 KIF16B DNAH2 CHD3 XRCC5 DYNC1H1 KIF1C

4.54e-04441828GO:0016887
GeneOntologyMolecularFunctioncytoskeletal protein binding

MYH6 LRPPRC DST KIF15 BRCA2 IQGAP2 SPTAN1 IFT81 KIF16B FMN2 AIF1L IQGAP3 KIF1C

5.12e-0410998213GO:0008092
GeneOntologyMolecularFunction1-phosphatidylinositol-4-phosphate 5-kinase activity

PIP4K2A PIP4K2B

5.89e-049822GO:0016308
GeneOntologyMolecularFunctionactin binding

MYH6 LRPPRC DST IQGAP2 SPTAN1 FMN2 AIF1L IQGAP3

7.80e-04479828GO:0003779
GeneOntologyMolecularFunctionATP-dependent activity

HSP90B1 MYH6 KIF15 KIF16B DNAH2 CHD3 XRCC5 DYNC1H1 KIF1C

9.21e-04614829GO:0140657
GeneOntologyMolecularFunctionhistone H3K36 methyltransferase activity

PRDM9 PRDM7

1.26e-0313822GO:0046975
GeneOntologyMolecularFunctionmicrotubule binding

LRPPRC DST KIF15 KIF16B FMN2 KIF1C

1.68e-03308826GO:0008017
GeneOntologyBiologicalProcessmicrotubule-based process

FSIP2 LRPPRC XRN2 DST KIF15 BRCA2 IFT81 KIF16B DNAH2 DOCK7 FMN2 CHD3 HYDIN DYNC1H1 SPDL1 KIF1C

3.50e-0610588216GO:0007017
GeneOntologyBiologicalProcessmicrotubule-based movement

FSIP2 LRPPRC DST KIF15 IFT81 KIF16B DNAH2 FMN2 HYDIN DYNC1H1 KIF1C

3.95e-064938211GO:0007018
GeneOntologyBiologicalProcessorganelle assembly

FSIP2 MYH6 NPTX1 RPGRIP1L KIF15 IFT81 PIP4K2A DNAH2 DOCK7 PIP4K2B ZPBP2 XRCC5 HYDIN DYNC1H1 TNS3

3.72e-0511388215GO:0070925
GeneOntologyBiologicalProcessmitotic actomyosin contractile ring assembly

IQGAP2 IQGAP3

4.67e-053822GO:1903475
GeneOntologyBiologicalProcessmitotic actomyosin contractile ring assembly actin filament organization

IQGAP2 IQGAP3

4.67e-053822GO:1903479
GeneOntologyBiologicalProcessassembly of actomyosin apparatus involved in mitotic cytokinesis

IQGAP2 IQGAP3

4.67e-053822GO:1902407
GeneOntologyBiologicalProcess1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

PIP4K2A PIP4K2B

4.67e-053822GO:1902635
GeneOntologyBiologicalProcessactomyosin contractile ring assembly actin filament organization

IQGAP2 IQGAP3

9.32e-054822GO:2000689
GeneOntologyBiologicalProcesspositive regulation of reciprocal meiotic recombination

PRDM9 PRDM7

9.32e-054822GO:0010845
GeneOntologyBiologicalProcess1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process

PIP4K2A PIP4K2B

9.32e-054822GO:1902633
GeneOntologyBiologicalProcessregulation of reciprocal meiotic recombination

PRDM9 PRDM7

9.32e-054822GO:0010520
GeneOntologyBiologicalProcessretrograde axonal transport

DST DYNC1H1 KIF1C

1.15e-0424823GO:0008090
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

FSIP2 DST KIF15 BRCA2 DNAH2 DOCK7 FMN2 CHD3 HYDIN DYNC1H1 SPDL1

1.28e-047208211GO:0000226
GeneOntologyCellularComponentsupramolecular fiber

MYH6 LRPPRC RPGRIP1L DST KIF15 IQGAP2 PPP1R12B SPTAN1 KIF16B DNAH2 FMN2 AIF1L DYNC1H1 KIF1C

1.60e-0411798114GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

MYH6 LRPPRC RPGRIP1L DST KIF15 IQGAP2 PPP1R12B SPTAN1 KIF16B DNAH2 FMN2 AIF1L DYNC1H1 KIF1C

1.72e-0411878114GO:0099081
GeneOntologyCellularComponentmicrotubule

LRPPRC RPGRIP1L DST KIF15 IQGAP2 KIF16B DNAH2 DYNC1H1 KIF1C

2.18e-04533819GO:0005874
GeneOntologyCellularComponentprotein phosphatase 4 complex

PPP4R3B PPP4R2

2.20e-046812GO:0030289
GeneOntologyCellularComponentmicrotubule associated complex

KIF15 KIF16B DNAH2 DYNC1H1 KIF1C

4.07e-04161815GO:0005875
GeneOntologyCellularComponentcell cortex

DST IQGAP2 SPTAN1 FMN2 MELK IQGAP3 DYNC1H1

5.91e-04371817GO:0005938
GeneOntologyCellularComponentaxon

CPNE6 DST SPTAN1 RAPGEF4 DOCK7 PYGB NRSN1 IL1R1 DYNC1H1 ADCY9 KIF1C

6.29e-048918111GO:0030424
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

LRPPRC RPGRIP1L DST KIF15 IQGAP2 KIF16B DNAH2 FMN2 AIF1L DYNC1H1 KIF1C

6.77e-048998111GO:0099513
GeneOntologyCellularComponentcentrosome

STK3 PPP4R3B RPGRIP1L KIF15 BRCA2 PPP4R2 IFT81 CHD3 DYNC1H1 SPDL1

7.68e-047708110GO:0005813
GeneOntologyCellularComponentmicrotubule organizing center

STK3 PPP4R3B RPGRIP1L KIF15 BRCA2 PPP4R2 IFT81 CHD3 CCDC178 DYNC1H1 SPDL1

8.11e-049198111GO:0005815
GeneOntologyCellularComponentkinesin complex

KIF15 KIF16B KIF1C

9.08e-0449813GO:0005871
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

RPGRIP1L DST DNAH2 HYDIN DYNC1H1 KIF1C

1.45e-03317816GO:0032838
GeneOntologyCellularComponentactin cytoskeleton

MYH6 DST IQGAP2 PPP1R12B SPTAN1 FMN2 AIF1L TNS3

1.74e-03576818GO:0015629
GeneOntologyCellularComponentsecretory granule

SPAM1 BRCA2 IQGAP2 CADPS SPTAN1 PLA2G4A PYGB ZPBP2 XRCC5 PCDH7 DYNC1H1

1.79e-0310148111GO:0030141
GeneOntologyCellularComponentaxon cytoplasm

DST DYNC1H1 KIF1C

2.34e-0368813GO:1904115
DomainRasGAP_C

IQGAP2 IQGAP3

5.56e-053812IPR000593
DomainRasGAP_C

IQGAP2 IQGAP3

5.56e-053812PF03836
DomainPInositol-4-P-5-kinase

PIP4K2A PIP4K2B

3.85e-047812IPR023610
DomainPIPKc

PIP4K2A PIP4K2B

5.11e-048812SM00330
Domain-

PIP4K2A PIP4K2B

5.11e-0488123.30.800.10
DomainSSXRD

PRDM9 PRDM7

5.11e-048812PF09514
DomainSSXRD_motif

PRDM9 PRDM7

5.11e-048812IPR019041
DomainPIP5K

PIP4K2A PIP4K2B

5.11e-048812PF01504
DomainDHC_N1

DNAH2 DYNC1H1

5.11e-048812PF08385
DomainPIPK

PIP4K2A PIP4K2B

5.11e-048812PS51455
DomainPInositol-4-P-5-kinase_N

PIP4K2A PIP4K2B

5.11e-048812IPR027484
DomainPInositol-4-P-5-kinase_C

PIP4K2A PIP4K2B

5.11e-048812IPR027483
Domain-

PIP4K2A PIP4K2B

5.11e-0488123.30.810.10
DomainPInositol-4-P-5-kinase_core

PIP4K2A PIP4K2B

5.11e-048812IPR002498
DomainDynein_heavy_dom-1

DNAH2 DYNC1H1

5.11e-048812IPR013594
DomainC2_dom

CPNE6 RPGRIP1L CADPS PLA2G4A TNS3

7.35e-04164815IPR000008
DomainKinesin-like_fam

KIF15 KIF16B KIF1C

8.56e-0443813IPR027640
DomainKINESIN_MOTOR_1

KIF15 KIF16B KIF1C

9.16e-0444813PS00411
Domain-

KIF15 KIF16B KIF1C

9.16e-04448133.40.850.10
DomainKinesin_motor_dom

KIF15 KIF16B KIF1C

9.16e-0444813IPR001752
DomainKinesin

KIF15 KIF16B KIF1C

9.16e-0444813PF00225
DomainKINESIN_MOTOR_2

KIF15 KIF16B KIF1C

9.16e-0444813PS50067
DomainKISc

KIF15 KIF16B KIF1C

9.16e-0444813SM00129
DomainKRAB_RELATED

PRDM9 PRDM7

9.96e-0411812PS50806
DomainKrueppel-associated_box-rel

PRDM9 PRDM7

1.40e-0313812IPR003655
DomainRasGAP

IQGAP2 IQGAP3

1.63e-0314812SM00323
DomainDynein_heavy_chain_D4_dom

DNAH2 DYNC1H1

1.63e-0314812IPR024317
DomainDynein_HC_stalk

DNAH2 DYNC1H1

1.63e-0314812IPR024743
DomainDynein_heavy_dom-2

DNAH2 DYNC1H1

1.63e-0314812IPR013602
DomainDHC_N2

DNAH2 DYNC1H1

1.63e-0314812PF08393
DomainMT

DNAH2 DYNC1H1

1.63e-0314812PF12777
DomainAAA_8

DNAH2 DYNC1H1

1.63e-0314812PF12780
DomainATPase_dyneun-rel_AAA

DNAH2 DYNC1H1

1.63e-0314812IPR011704
DomainRasGAP_CS

IQGAP2 IQGAP3

1.63e-0314812IPR023152
DomainAAA_5

DNAH2 DYNC1H1

1.63e-0314812PF07728
DomainDHC_fam

DNAH2 DYNC1H1

1.88e-0315812IPR026983
DomainRasGAP

IQGAP2 IQGAP3

1.88e-0315812PF00616
DomainRAS_GTPASE_ACTIV_1

IQGAP2 IQGAP3

1.88e-0315812PS00509
DomainRAS_GTPASE_ACTIV_2

IQGAP2 IQGAP3

1.88e-0315812PS50018
DomainDynein_heavy_dom

DNAH2 DYNC1H1

1.88e-0315812IPR004273
DomainDynein_heavy

DNAH2 DYNC1H1

1.88e-0315812PF03028
Domain-

IQGAP2 IQGAP3

2.14e-03168121.10.506.10
DomainC2

CPNE6 RPGRIP1L CADPS PLA2G4A

2.53e-03131814PF00168
DomainRasGAP_dom

IQGAP2 IQGAP3

2.72e-0318812IPR001936
DomainCH

DST IQGAP2 IQGAP3

2.83e-0365813SM00033
DomainC2

CPNE6 RPGRIP1L CADPS PLA2G4A

2.98e-03137814SM00239
DomainC2

CPNE6 RPGRIP1L CADPS PLA2G4A

3.39e-03142814PS50004
DomainCH

DST IQGAP2 IQGAP3

3.49e-0370813PF00307
DomainIQ

MYH6 IQGAP2 IQGAP3

3.63e-0371813PF00612
Domain-

DST IQGAP2 IQGAP3

3.63e-03718131.10.418.10
DomainCH

DST IQGAP2 IQGAP3

3.93e-0373813PS50021
DomainCH-domain

DST IQGAP2 IQGAP3

4.24e-0375813IPR001715
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

STK3 LRPPRC MYBBP1A XRN2 PTPN14 RPGRIP1L IQGAP2 PPP4R2 SCML1 IFT81 DOCK7 DZIP3 NDUFA10 CWC25 MELK IQGAP3 DYNC1H1 TEFM KIF1C

1.83e-101321821927173435
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

HSP90B1 MYH6 LRPPRC CPNE6 MYBBP1A DST NRDC IQGAP2 CADPS PPP1R12B SPTAN1 PIP4K2A RAPGEF4 DOCK7 PYGB CHD3 DYNC1H1

3.25e-081431821737142655
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

HSP90B1 MYH6 LRPPRC MYBBP1A DST IQGAP2 PPP1R12B SPTAN1 IFT81 TAF1B PIP4K2A DNAH2 PIP4K2B CHD3 HMGCL XRCC5 IL1R1

3.63e-081442821735575683
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

STK3 FSIP2 LRPPRC PTPN14 DST SASH1 SPTAN1 DOCK7 FMN2 MELK PCDH7 TNS3 KIF1C

1.11e-07861821336931259
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

PPP4R3B XRN2 PTPN14 RPGRIP1L KIF15 BRCA2 PPP4R2 PIP4K2A SECISBP2 PYGB ZMYM4

1.39e-07588821138580884
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

HSP90B1 LRPPRC MYBBP1A XRN2 PTPN14 DST SPTAN1 TAF1B PIP4K2A PYGB XRCC5 IFI16 MELK DYNC1H1 TNS3

5.64e-071353821529467282
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

LRPPRC MYBBP1A PTPN14 IQGAP2 XRCC5 IQGAP3 DYNC1H1

7.08e-0721182717314511
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PPP4R3B HSP90B1 MYBBP1A PTPN14 RPGRIP1L KIF15 PPP4R2 PPP1R12B SPTAN1 FMN2 PCDH7 ADCY9 TNS3

1.03e-061049821327880917
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

HSP90B1 LRPPRC MYBBP1A XRN2 NRDC SPTAN1 DOCK7 HMGCL GALNT5 XRCC5 PRDM7 NDUFA10 IQGAP3 DYNC1H1 SPDL1

1.08e-061425821530948266
Pubmed

LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.

HSP90B1 LRPPRC DST DNAH2 XRCC5 DYNC1H1

1.13e-0614282630809309
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

HSP90B1 MYH6 CPNE6 DST SASH1 BRCA2 SPTAN1 PYGB NDUFA10 DYNC1H1

2.07e-06621821022794259
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

MYBBP1A KIF15 SPTAN1 PLA2G4A CHD3 DYNC1H1 SPDL1

2.56e-0625682733397691
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

HSP90B1 LRPPRC MYBBP1A XRN2 DST SPTAN1 PYGB XRCC5 IQGAP3 HYDIN DYNC1H1

3.07e-06807821130575818
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PPP4R3B SDK2 DST SASH1 ARL6IP1 KIF16B MELK ZMYM4 ADCY9

4.46e-0652982914621295
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

HSP90B1 MYH6 LRPPRC CPNE6 XRN2 DST RRM2B PYGB CHD3 XRCC5 DYNC1H1

4.70e-06844821125963833
Pubmed

Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers.

IQGAP2 IQGAP3

5.49e-06282229073199
Pubmed

Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy.

PIP4K2A PIP4K2B

5.49e-06282229727621
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

HSP90B1 XRN2 DST DOCK7 CHD3 IFI16 MELK ZMYM4

5.80e-0641082826949251
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

DST KIF15 BRCA2 DOCK7 CHD3 NDUFA10 ZMYM4 SPDL1

6.68e-0641882834709266
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

HSP90B1 LRPPRC MYBBP1A XRN2 PTPN14 DST SPTAN1 DOCK7 XRCC5 NDUFA10 IFI16 IQGAP3 DYNC1H1

7.43e-061257821336526897
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

DUSP12 PPP4R3B LRPPRC MYBBP1A PPP4R2 SCML1 PPP1R12B XRCC5 DYNC1H1

8.46e-0657382928330616
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

LRPPRC MYBBP1A DOCK7 CHD3 NDUFA10 IQGAP3

8.64e-0620282624639526
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PPP4R3B HSP90B1 XRN2 DST CADPS SPTAN1 IFT81 RAPGEF4 FMN2 MIGA1 NDUFA10 DYNC1H1 ZMYM4

9.40e-061285821335914814
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

STK3 HSP90B1 LRPPRC MYBBP1A DOCK7 IFI16 DYNC1H1 TEFM KIF1C

1.24e-0560182933658012
Pubmed

Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.

FSIP2 MYH6 LRPPRC DST PYGB NDUFA10 DYNC1H1

1.37e-0533182729199018
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

PTPN14 DST SPTAN1 CHD3 LARS2 DYNC1H1 TNS3

1.40e-0533282737433992
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

HSP90B1 LRPPRC MYBBP1A XRN2 DST PPP1R12B SPTAN1 DOCK7 XRCC5 IFI16 DYNC1H1

1.41e-05949821136574265
Pubmed

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.

LRPPRC MYBBP1A XRN2 IQGAP2 SPTAN1 DYNC1H1

1.44e-0522182629991511
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

LRPPRC MYBBP1A DST KIF15 IQGAP2 SPTAN1 RAPGEF4 DOCK7 DZIP3 XRCC5 DYNC1H1

1.62e-05963821128671696
Pubmed

Functional analysis of the biochemical activity of mammalian phosphatidylinositol 5 phosphate 4-kinase enzymes.

PIP4K2A PIP4K2B

1.64e-05382230718367
Pubmed

LAF4 maps to mouse chromosome 1 and human chromosome 2q11.2-q12.

DST IL1R1

1.64e-0538228662235
Pubmed

The biology of IQGAP proteins: beyond the cytoskeleton.

IQGAP2 IQGAP3

1.64e-05382225722290
Pubmed

The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site.

PIP4K2A PIP4K2B

1.64e-05382225495341
Pubmed

Novel Genetic Variants of Sporadic Atrial Septal Defect (ASD) in a Chinese Population Identified by Whole-Exome Sequencing (WES).

MYH6 HYDIN

1.64e-05382229505555
Pubmed

IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold.

IQGAP2 IQGAP3

1.64e-05382222493426
Pubmed

Involvement of IQGAP family proteins in the regulation of mammalian cell cytokinesis.

IQGAP2 IQGAP3

1.64e-05382225229330
Pubmed

Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization.

PIP4K2A PIP4K2B

1.64e-05382223758345
Pubmed

Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors.

PIP4K2A PIP4K2B

1.64e-05382224209622
Pubmed

Epigenetic inactivation of the chromosomal stability control genes BRCA1, BRCA2, and XRCC5 in non-small cell lung cancer.

BRCA2 XRCC5

1.64e-05382217289874
Pubmed

Pharmacological inhibition of PI5P4Kα/β disrupts cell energy metabolism and selectively kills p53-null tumor cells.

PIP4K2A PIP4K2B

1.64e-05382234001596
Pubmed

The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis.

PIP4K2A PIP4K2B

1.64e-05382226774281
Pubmed

A transgenic insertional inner ear mutation on mouse chromosome 1.

DST IL1R1

1.64e-05382210763993
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

HSP90B1 MYH6 LRPPRC SPTAN1 PYGB XRCC5 IQGAP3 DYNC1H1 TNS3

2.21e-0564782926618866
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

LRPPRC MYBBP1A XRN2 DST SPTAN1 DOCK7 PYGB XRCC5 DYNC1H1

2.38e-0565382922586326
Pubmed

Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.

KIF15 KIF16B KIF1C

2.80e-05258239275178
Pubmed

A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate.

PIP4K2A PIP4K2B

3.28e-0548229367159
Pubmed

PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay.

PIP4K2A PIP4K2B

3.28e-05482233984270
Pubmed

Assignment of the human helix-loop-helix transcription factor gene musculin/activated B-cell factor-1 (MSC) to chromosome 8q21 and its mouse homologue (Msc) to the proximal region of chromosome 1.

DST IL1R1

3.28e-05482210198176
Pubmed

Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis.

PPP4R3B PPP4R2

3.28e-05482220876121
Pubmed

Valosin-containing protein (VCP) is a novel IQ motif-containing GTPase activating protein 1 (IQGAP1)-interacting protein.

IQGAP2 IQGAP3

3.28e-05482228970065
Pubmed

Characterization of the mouse JAB1 cDNA and protein.

DST IL1R1

3.28e-05482210721695
Pubmed

PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism.

PIP4K2A PIP4K2B

3.28e-05482231091439
Pubmed

Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes.

PRDM9 PRDM7

3.28e-05482218231586
Pubmed

Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.

HSP90B1 MYBBP1A XRN2 SPTAN1 XRCC5 DYNC1H1

3.29e-0525682632698014
Pubmed

Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.

LRPPRC MYBBP1A SPTAN1 PIP4K2A XRCC5

3.52e-0515682522952844
Pubmed

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.

STK3 PTPN14 SCML1 PIP4K2A DOCK7 PIP4K2B

4.42e-0527082624366813
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

HSP90B1 LRPPRC MYBBP1A DST DOCK7 XRCC5 PCDH7 DYNC1H1 ADCY9

4.45e-0570882939231216
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

HSP90B1 LRPPRC MYBBP1A PTPN14 RPGRIP1L DST KIF16B SECISBP2 MIGA1 XRCC5 LARS2 ADCY9 TEFM

4.60e-051496821332877691
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

HSP90B1 LRPPRC MYBBP1A XRN2 SPTAN1 PCDH7

4.80e-0527482634244482
Pubmed

Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1.

STK3 NRDC

5.47e-05582218362890
Pubmed

Distribution and localization of phosphatidylinositol 5-phosphate, 4-kinase alpha and beta in the brain.

PIP4K2A PIP4K2B

5.47e-05582232449185
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

RPGRIP1L SECISBP2 PIP4K2B AIF1L CWC25 MELK ADCY9 TNS3 SPDL1

5.81e-0573382934672954
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

PTPN14 IQGAP2 KIF16B DOCK7 FMN2 PCDH7 ADCY9 TNS3

6.02e-0556982830639242
Pubmed

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.

HSP90B1 MYH6 SPTAN1 DYNC1H1

6.85e-059282437343697
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

HSP90B1 LRPPRC MYBBP1A DST IQGAP2 SPTAN1 DOCK7 AIF1L XRCC5 IQGAP3 DYNC1H1

8.00e-051149821135446349
Pubmed

Branches of the B cell antigen receptor pathway are directed by protein conduits Bam32 and Carma1.

PIP4K2A PIP4K2B

8.19e-05682214614850
Pubmed

IQ-motif selectivity in human IQGAP2 and IQGAP3: binding of calmodulin and myosin essential light chain.

IQGAP2 IQGAP3

8.19e-05682221299499
Pubmed

Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.

LRPPRC DST SPTAN1 DOCK7 DYNC1H1

9.18e-0519182533762435
Pubmed

Defining the membrane proteome of NK cells.

HSP90B1 LRPPRC MYBBP1A XRN2 KIF15 ARL6IP1 PYGB XRCC5 IFI16 MELK DYNC1H1

9.24e-051168821119946888
Pubmed

All kinesin superfamily protein, KIF, genes in mouse and human.

KIF15 KIF16B KIF1C

9.26e-053782311416179
Pubmed

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

CPNE6 DST IQGAP2 PYGB IL1R1 IQGAP3

9.99e-0531382620800603
Pubmed

STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.

HSP90B1 MYBBP1A XRN2 SPTAN1 XRCC5 IFI16

1.05e-0431682631665637
Pubmed

Localization of mRNAs for phosphatidylinositol phosphate kinases in the mouse brain during development.

PIP4K2A PIP4K2B

1.14e-04782215018809
Pubmed

The yin-yang of PR-domain family genes in tumorigenesis.

PRDM9 PRDM7

1.14e-04782210668202
Pubmed

Chromosomal localization of mouse bullous pemphigoid antigens. BPAG1 and BPAG2: identification of a new region of homology between mouse and human chromosomes.

DST IL1R1

1.14e-0478228432531
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

HSP90B1 LRPPRC MYBBP1A XRN2 IQGAP2 SPTAN1 XRCC5 DYNC1H1

1.17e-0462682833644029
Pubmed

Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.

HSP90B1 MYBBP1A NRDC SPTAN1 DYNC1H1

1.31e-0420682522174317
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

HSP90B1 MYBBP1A NPTX1 CADPS SPTAN1 DZIP3 FMN2

1.33e-0447582731040226
Pubmed

Genetic loci associated with circulating levels of very long-chain saturated fatty acids.

DOCK7 IL1R1 PCDH7

1.36e-044282325378659
Pubmed

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.

LRPPRC MYBBP1A SPTAN1 SECISBP2 XRCC5 DYNC1H1

1.40e-0433382632665550
Pubmed

Quantitative analysis of PPT1 interactome in human neuroblastoma cells.

HSP90B1 LRPPRC SPTAN1 DOCK7 DYNC1H1

1.43e-0421082526217791
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

PPP4R3B HSP90B1 KIF15 NRDC PPP4R2 SPTAN1 PLA2G4A PYGB XRCC5 DYNC1H1 TNS3 SPDL1

1.51e-041455821222863883
Pubmed

Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter.

MYBBP1A DOCK7

1.52e-04882219129230
Pubmed

Btk-dependent regulation of phosphoinositide synthesis.

PIP4K2A PIP4K2B

1.52e-04882215046600
Pubmed

A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication.

PPP4R3B PPP4R2

1.52e-04882218614045
Pubmed

Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain.

PIP4K2A PIP4K2B

1.52e-04882220622009
Pubmed

SET domains and histone methylation.

PRDM9 PRDM7

1.52e-04882214675547
Pubmed

Hippo pathway-dependent and -independent roles of RASSF6.

STK3 NRDC

1.52e-04882219797269
Pubmed

HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus.

DYNC1H1 KIF1C

1.52e-04882225818806
Pubmed

The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival.

LRPPRC MYBBP1A XRN2 PIP4K2A PIP4K2B

1.78e-0422082531822558
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

XRN2 DST SPTAN1 DYNC1H1

1.92e-0412082431413325
Pubmed

Genetic polymorphisms in double-strand break DNA repair genes associated with risk of oral premalignant lesions.

BRCA2 XRCC5

1.96e-04982218579371
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

DST PPP4R2 SPTAN1 DOCK7 FMN2 DYNC1H1 SPDL1

1.96e-0450682730890647
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

LRPPRC MYBBP1A XRN2 PTPN14 SPTAN1 SECISBP2 XRCC5 MELK

2.01e-0467882830209976
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

MYBBP1A RPGRIP1L DST KIF15 CADPS SPTAN1 ZMYM4

2.14e-0451382725798074
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

SDK2 RRM2B PIP4K2B XRCC5 ZMYM4 TNS3

2.16e-0436182626167880
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

DST RGS5 SPTAN1 IFT81 AOAH SECISBP2 XRCC5 NDUFA10 MELK HYDIN SPDL1

2.24e-041293821115342556
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

HSP90B1 LRPPRC MYBBP1A XRN2 NPTX1 DST SPTAN1 DOCK7 XRCC5 DYNC1H1

2.29e-041082821038697112
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

MYBBP1A DST DNAH2 PRDM7 TNS3

2.32e-0423382537704626
Pubmed

PI(5)P regulates autophagosome biogenesis.

PIP4K2A PIP4K2B

2.44e-041082225578879
InteractionLINC01554 interactions

HSP90B1 LRPPRC DST DNAH2 XRCC5 DYNC1H1

2.48e-05142826int:LINC01554
InteractionLYN interactions

HSP90B1 MYBBP1A SDK2 PTPN14 DST IQGAP2 SPTAN1 DOCK7 FMN2 IL1R1 PCDH7 ADCY9

3.30e-057208212int:LYN
InteractionKCTD13 interactions

HSP90B1 MYH6 LRPPRC CPNE6 MYBBP1A DST NRDC IQGAP2 CADPS PPP1R12B SPTAN1 PIP4K2A RAPGEF4 DOCK7 PYGB CHD3 DYNC1H1

3.77e-0513948217int:KCTD13
InteractionC11orf52 interactions

PTPN14 DST IQGAP2 SPTAN1 DOCK7 FMN2 PCDH7 ADCY9

3.89e-05311828int:C11orf52
InteractionYWHAQ interactions

STK3 PPP4R3B LRPPRC PTPN14 RPGRIP1L DST SASH1 DOCK7 LARS2 IFI16 MELK PCDH7 DYNC1H1 TNS3 KIF1C

3.96e-0511188215int:YWHAQ
InteractionMKI67 interactions

HSP90B1 XRN2 DST KIF15 BRCA2 DNAH2 DOCK7 CHD3 IFI16 MELK ZMYM4

6.15e-056488211int:MKI67
InteractionDSCAM interactions

XRN2 SDK2 DST CADPS RAPGEF4 DYNC1H1

7.02e-05171826int:DSCAM
InteractionHSPB8 interactions

DUSP12 MYH6 BRCA2 IQGAP2 PYGB NRSN1

7.25e-05172826int:HSPB8
InteractionPOLR1E interactions

LRPPRC MYBBP1A XRN2 BRCA2 IQGAP2 IFT81 IFI16 ZMYM4

8.90e-05350828int:POLR1E
InteractionAGR2 interactions

HSP90B1 LRPPRC CPNE6 MYBBP1A XRN2 DST SPTAN1 PYGB NRSN1 XRCC5 IQGAP3 HYDIN DYNC1H1

9.60e-059348213int:AGR2
InteractionLGR4 interactions

LRPPRC MYBBP1A DOCK7 CHD3 NRSN1 NDUFA10 IQGAP3

9.60e-05262827int:LGR4
InteractionSTK3 interactions

STK3 MYH6 PTPN14 DST NRDC IFI16

9.61e-05181826int:STK3
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

RPGRIP1L PPP1R12B DZIP3 PCDH7 HYDIN

1.04e-04181475694
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF15 KIF16B KIF1C

2.31e-0446473622
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

PRDM9 PRDM7

8.77e-04174721197
CoexpressionHALLMARK_MITOTIC_SPINDLE

LRPPRC DST KIF15 BRCA2 PPP4R2 SPTAN1 DYNC1H1

3.07e-06199827M5893
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

TDRD7 HSP90B1 KIF15 IQGAP2 PPP4R2 SCML1 RRM2B TAF1B KIF16B IFI16 SPDL1

6.21e-066568211M18979
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

TDRD7 STK3 LRPPRC DST SASH1 BRCA2 PIP4K2A IL1R1 LARS2 MELK ZMYM4 ADCY9

1.38e-058568212M4500
CoexpressionGSE26351_WNT_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_UP

XRN2 KIF15 PIP4K2A SECISBP2 UGT3A2 AIF1L

3.85e-05199826M8477
CoexpressionGSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_UP

CLEC4E SASH1 PIP4K2A DOCK7 PLA2G4A IL1R1

3.96e-05200826M4568
CoexpressionMENON_FETAL_KIDNEY_4_PODOCYTES

HSP90B1 PTPN14 DST IQGAP2 CHD3 AIF1L

4.67e-05206826M39254
CoexpressionGAO_LARGE_INTESTINE_ADULT_CA_ENTEROENDOCRINE_CELLS

SDK2 CADPS AOAH RAPGEF4 DZIP3 FMN2 OSCP1

5.61e-05312827M39161
CoexpressionGRYDER_PAX3FOXO1_ENHANCERS_IN_TADS

DUSP12 SDK2 C5orf22 SASH1 BRCA2 PPP4R2 RRM2B IFT81 LARS2 ADCY9 TNS3 SPDL1

6.86e-0510098212M157
ToppCellNon-neuronal-Dividing-IPC-IPC-div1-28|World / Primary Cells by Cluster

HSP90B1 KIF15 BRCA2 ARL6IP1 MELK IQGAP3 SPDL1

8.56e-08199827787688b68ae5d8768c0a24673ae07ab07616764a
ToppCellNon-neuronal-Dividing-IPC-IPC-div1|World / Primary Cells by Cluster

HSP90B1 KIF15 BRCA2 ARL6IP1 MELK IQGAP3 SPDL1

8.56e-0819982772823f26ecabcae1b514b7629cfce010c97b929a
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF15 BRCA2 RTP2 MELK IQGAP3 SPDL1

1.81e-071348264d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RPGRIP1L CCDC73 BRCA2 RAPGEF4 MELK HYDIN

4.61e-07157826410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPAM1 KIF15 BRCA2 AOAH MELK IQGAP3

8.42e-071748267b318796728001c17b4043d2b033330c7be40c78
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPAM1 KIF15 BRCA2 MELK IQGAP3 SPDL1

1.03e-06180826334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

HSP90B1 KIF15 ARL6IP1 MELK IQGAP3 SPDL1

1.20e-061858266aeae77a087d695b1e58c5f63265e7113aa2e343
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

KIF15 CCDC73 BRCA2 HEMGN MELK IQGAP3

1.63e-06195826764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF15 BRCA2 ARL6IP1 RGS5 MELK IQGAP3

1.68e-06196826eb8c9a4a5eb21d43ff7b25deae5896c236f669b9
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF15 BRCA2 RGS5 IL1R1 MELK IQGAP3

1.73e-0619782676b61e60a757e58b465569538e632d6d9953e89a
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DST SASH1 SPTAN1 RAPGEF4 IFI16 DYNC1H1

1.89e-0620082672ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DST SASH1 SPTAN1 RAPGEF4 IFI16 DYNC1H1

1.89e-062008265c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DST SASH1 RGS5 SPTAN1 RAPGEF4 IFI16

1.89e-06200826b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF15 CADPS RAPGEF4 MELK IQGAP3

1.17e-05160825830e3ef8c9708d25872c3052a0b2682fa9372111
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF15 BRCA2 MELK IQGAP3 SPDL1

1.36e-0516582588681101d7cf60b99b8ace5d8c0944323b937306
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF15 IQGAP2 PIP4K2A MELK SPDL1

1.48e-05168825b7cd33f5da4f37b9384fc3bd3ca01fbc790accfc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF15 BRCA2 MELK IQGAP3 SPDL1

1.52e-05169825b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellDividing_Macrophages-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

KIF15 BRCA2 ARL6IP1 MELK IQGAP3

1.52e-05169825bc859a103cad567caf50c3c3882d2d2017807c73
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF15 BRCA2 AOAH MELK IQGAP3

1.61e-0517182555c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCell3'_v3-bone_marrow-Lymphocytic_B-GC_B_(I)|bone_marrow / Manually curated celltypes from each tissue

CPNE6 BRCA2 PLA2G4A MELK TNS3

1.70e-0517382567f0f0bf88eab69987b71d96b864ed2b14975adb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF15 BRCA2 ZPBP2 MELK IQGAP3

1.70e-05173825a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors|lymph-node_spleen / Manually curated celltypes from each tissue

KIF15 DDO UGT3A2 MELK IQGAP3

1.75e-05174825029394e107bf7ad58056d2216070aa2e964fff12
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KIF15 BRCA2 PLA2G4A MELK SPDL1

1.80e-051758250b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

DST PPP1R12B SPTAN1 DZIP3 DYNC1H1

1.90e-05177825e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellDividing_Macrophages-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

KIF15 BRCA2 MELK IQGAP3 SPDL1

1.95e-051788251893fadac2ec3d5de0a641e57b7b2f962012a9ba
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

HSP90B1 KIF15 ARL6IP1 IQGAP3 SPDL1

2.01e-051798256718cadcc2d3b64717ed84244ef1242d392662dc
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac|lymph-node_spleen / Manually curated celltypes from each tissue

SASH1 KIF15 PLA2G4A MELK TNS3

2.06e-051808254eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2|TCGA-Skin / Sample_Type by Project: Shred V9

C5orf22 DOCK7 MIGA1 PRDM7 DYNC1H1

2.12e-051818259d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCellDividing_Macrophages-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

KIF15 BRCA2 MELK IQGAP3 SPDL1

2.29e-05184825f15ce786d25c6546804a6d1efcc2ad645f2ef54e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN14 SASH1 AIF1L HYDIN TNS3

2.29e-05184825da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH6 KIF15 MELK IQGAP3 SPDL1

2.29e-05184825d1e0e3b0eed2db8a5b7e3d6f81294667e4ba64e5
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

KIF15 BRCA2 ARL6IP1 MELK IQGAP3

2.35e-051858259766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic|bone_marrow / Manually curated celltypes from each tissue

SDK2 DST KIF15 MELK IQGAP3

2.35e-051858259d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF15 BRCA2 AOAH MELK IQGAP3

2.48e-0518782573931a5ea73799095daff100b5f18853c57c74dc
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDK2 DST CADPS RAPGEF4 IL1R1

2.54e-05188825a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF15 BRCA2 RAPGEF4 MELK IQGAP3

2.67e-0519082531de1727822e9818652946dfb962daee77ffad68
ToppCellDividing_Macrophages-HP_01|World / lung cells shred on cell class, cell subclass, sample id

KIF15 BRCA2 MELK IQGAP3 SPDL1

2.74e-051918253e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF15 BRCA2 IFI16 MELK IQGAP3

2.74e-05191825ff2cc4c10aa584b3daeaaf23cd8ee09bdbdf684d
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIF15 ARL6IP1 MELK IQGAP3 SPDL1

2.74e-051918250ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCellEndothelial-Endothelial-D_(cycle)|Endothelial / shred on cell class and cell subclass (v4)

KIF15 ARL6IP1 MELK IQGAP3 SPDL1

2.74e-05191825a3c5a913a99f17633c140ec9ece81b73e59e0715
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l12-14|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF15 ARL6IP1 UGT3A2 OSCP1 IQGAP3

2.81e-0519282552d0aa51e3b6ab3608a5f40bdde9f8134b3afd94
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KIF15 ARL6IP1 MELK IQGAP3 SPDL1

2.81e-0519282527723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KIF15 ARL6IP1 MELK IQGAP3 SPDL1

2.81e-051928250a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIF15 ARL6IP1 MELK IQGAP3 SPDL1

2.81e-05192825026f3e38970bea1e6e8d76a4e2becdfb8484b2ff
ToppCellProliferating|World / shred by cell class for mouse tongue

KIF15 ARL6IP1 MELK IQGAP3 SPDL1

2.81e-05192825f081f3f957cc782294e118fcc1055f6a4264ee98
ToppCellControl-Lymphoid-Proliferating_CD4_T_cells|Control / Condition, Lineage and Cell class

KIF15 BRCA2 MELK IQGAP3 SPDL1

2.88e-0519382533d409d6ed1c606337248587ad997ac5f67f081d
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF15 BRCA2 ARL6IP1 MELK IQGAP3

2.88e-05193825444de545117dae8ab24a22880583ac2f0b2d6eac
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF15 BRCA2 MELK IQGAP3 SPDL1

2.95e-051948251a2090e997c70433d07f56bf7cb0a50c4151118c
ToppCellControl-Lymphocyte-T_NK-T_NK_proliferative|Control / Disease, Lineage and Cell Type

KIF15 BRCA2 AIF1L MELK SPDL1

2.95e-05194825844731b7943d1cfca819b7b89e4e62067bfa0230
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RPGRIP1L IFT81 DNAH2 DZIP3 HYDIN

2.95e-051948254a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|367C / Donor, Lineage, Cell class and subclass (all cells)

KIF15 BRCA2 MELK IQGAP3 SPDL1

2.95e-05194825a12b64945e10f00aa983678a02586c59badc1570
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIF15 BRCA2 MELK IQGAP3 SPDL1

3.02e-05195825926eb3fc5d028be936885bea0654a77db3107234
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST CADPS RAPGEF4 FMN2 DYNC1H1

3.02e-051958253e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST CADPS RAPGEF4 FMN2 DYNC1H1

3.02e-051958257796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_1|343B / Donor, Lineage, Cell class and subclass (all cells)

KIF15 BRCA2 MELK IQGAP3 SPDL1

3.02e-0519582547a01b8a92eebeb34ac7f70bf1ab4613a326e24f
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KIF15 BRCA2 MELK IQGAP3 SPDL1

3.10e-051968259591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF15 BRCA2 IQGAP2 MELK IQGAP3

3.10e-051968255905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF15 ARL6IP1 MELK IQGAP3 SPDL1

3.10e-0519682520383d576708b7e4bfce3e9fe40548cce496e3cb
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IFT81 DNAH2 DZIP3 OSCP1 HYDIN

3.10e-0519682527b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIF15 BRCA2 MELK IQGAP3 SPDL1

3.10e-0519682573f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF15 BRCA2 ARL6IP1 MELK IQGAP3

3.10e-0519682535cc0986dc3fc4b89e960a565b8f9810b1688e09
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF15 ARL6IP1 MELK IQGAP3 SPDL1

3.10e-051968250644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF15 ARL6IP1 MELK IQGAP3 SPDL1

3.18e-05197825a41420d4b6d502c2f594c054c7efbb5d4eac83ff
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF15 BRCA2 ARL6IP1 MELK IQGAP3

3.18e-051978252a89a724e8c15a5bb167fdad7eed31444d8c3d68
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF15 ARL6IP1 MELK IQGAP3 SPDL1

3.18e-051978251c89d6836eed30c50c765f7dde9cc8ee15c363d2
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IFT81 DNAH2 DZIP3 OSCP1 HYDIN

3.25e-05198825ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCelldistal-Hematologic-Proliferating_Macrophage-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KIF15 BRCA2 MELK IQGAP3 SPDL1

3.25e-051988258afeb1f9bc9d8551482c8fefe4c5f88d9cd13ee2
ToppCellParenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DST PPP1R12B AIF1L PCDH7 KIF1C

3.25e-05198825cc2b5b632e73e44bb60050f0db10d8f0dbb859fa
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIF15 BRCA2 MELK PCDH7 IQGAP3

3.25e-05198825f088badb90c6c2d916195f5649eda102119c9ac6
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_dorsal_progenitors|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

KIF15 BRCA2 MELK IQGAP3 SPDL1

3.25e-05198825dada1c19a261c8e1090957cd7e37f2a43a9fe14f
ToppCell15-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

KIF15 ARL6IP1 MELK IQGAP3 SPDL1

3.33e-051998255c8b847b794b3e88722f5b841f2539a27251106c
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF15 BRCA2 ARL6IP1 MELK IQGAP3

3.33e-0519982513ff6c26ebcc663ef8e5559ab9be99dab848abe7
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF15 ARL6IP1 RRM2B MELK SPDL1

3.33e-05199825c9d15c84b9f8c87b4ea0008be7d5efc5f45efd1a
ToppCellMNPs-Dividing_Macrophages|MNPs / lung cells shred on cell class, cell subclass, sample id

KIF15 BRCA2 MELK IQGAP3 SPDL1

3.33e-051998255952980d0ece5d73f3e9f340c56a38b34d2f2309
ToppCell18-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

DST KIF15 MELK IQGAP3 SPDL1

3.33e-051998257ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCellBiopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

KIF15 BRCA2 PRDM7 MELK IQGAP3

3.33e-051998254fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCell10x5'-Lung-Myeloid_Mac-Cycling_Myeloid-Mac|Lung / Manually curated celltypes from each tissue

KIF15 BRCA2 ARL6IP1 MELK IQGAP3

3.33e-05199825dee1cf8ee850a2bd57349418a9bcc0948fe9ac9e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF15 BRCA2 ARL6IP1 MELK IQGAP3

3.33e-051998254af38f5e9d2229d64f7ecdf9c00b4d67e5f86a51
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

KIF15 BRCA2 MELK IQGAP3 SPDL1

3.33e-0519982588d130e2451e61afb710edf552e6b346b9fcfb2b
ToppCellDividing_Macrophages|World / lung cells shred on cell class, cell subclass, sample id

KIF15 BRCA2 MELK IQGAP3 SPDL1

3.33e-051998255c755b6876e164dc847ef7c723f850f227cf3a87
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KIF15 BRCA2 MELK IQGAP3 SPDL1

3.33e-05199825be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellParenchyma_Control_(B.)-Immune-TX-TRAM-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CLEC4E IQGAP2 KIF16B CCRL2 TNS3

3.41e-052008257c56935446f10d202eafa1f9ee7cb0aae4c2607e
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Stem_cells-Neuroepithelial_cell|3m / Sample Type, Dataset, Time_group, and Cell type.

KIF15 BRCA2 AIF1L MELK IQGAP3

3.41e-052008252938a029fa0478be561574ace91f95c4a528b2d4
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

KIF15 BRCA2 MELK IQGAP3 SPDL1

3.41e-052008259bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellControl-Control-Lymphocyte-T/NK-dn_T|Control / Disease, condition lineage and cell class

PPP1R12B PIP4K2A DZIP3 CHD3 AIF1L

3.41e-0520082510882c59b7aaf8bd4b5c00aa4ddbb9f7ac5b2cf5
ToppCellLPS_only-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

DST SASH1 SPTAN1 RAPGEF4 IFI16

3.41e-0520082581e76508c9050d533853d5fd2f3097b27613d836
ToppCellControl_saline-Endothelial-Endothelial-Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

DST RGS5 SPTAN1 RAPGEF4 IFI16

3.41e-052008253b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCellBiopsy_Control_(H.)-Immune-Proliferating_Macrophages|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

KIF15 BRCA2 MELK IQGAP3 SPDL1

3.41e-05200825ce9fad55f779afd3d6c5a9c5a15e2d9f548b7c7e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF15 BRCA2 ARL6IP1 MELK IQGAP3

3.41e-0520082528c702449040ac15fe4e0c6340bb6f137e88539d
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Stem_cells|3m / Sample Type, Dataset, Time_group, and Cell type.

KIF15 BRCA2 AIF1L MELK IQGAP3

3.41e-05200825cfe017b4a4d604a553d0a3df9659687f38e9a7af
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DST SASH1 SPTAN1 IFI16 DYNC1H1

3.41e-0520082579e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SASH1 RGS5 SPTAN1 RAPGEF4 IFI16

3.41e-05200825a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCellLAM-Myeloid-pMacrophage|LAM / Condition, Lineage and Cell class

KIF15 BRCA2 MELK IQGAP3 SPDL1

3.41e-052008257e233d037165c9d3607604aaaf0f368e266567d3
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF15 BRCA2 ARL6IP1 MELK IQGAP3

3.41e-052008255e1b38e2aa8901bfb2623249f7b6302e97d56ace
ToppCellLPS_anti-TNF-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DST SASH1 SPTAN1 RAPGEF4 IFI16

3.41e-052008251d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCellLPS_IL1RA_TNF-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SASH1 RGS5 SPTAN1 RAPGEF4 IFI16

3.41e-05200825d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCellLPS_anti-TNF-Endothelial-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DST SASH1 SPTAN1 RAPGEF4 IFI16

3.41e-0520082560d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCellNon-neuronal-Dividing-Radial_Glia-vRG-17|World / Primary Cells by Cluster

KIF15 BRCA2 ARL6IP1 MELK IQGAP3

3.41e-052008254417f14d45ce683c1a45ec989ae63ee6c047353e
ToppCell(3)_MNP-(3)_DC_Monocyte_Dividing|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

KIF15 BRCA2 MELK IQGAP3 SPDL1

3.41e-05200825d94fe9bd6ee7c1fed14666f24de41bda014e299b
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

DST SASH1 SPTAN1 RAPGEF4 IFI16

3.41e-052008254bb609a284d4e6066f17470a1736076aa4a1f84c
Diseasecancer (implicated_via_orthology)

STK3 DST BRCA2 PIP4K2A PIP4K2B FRMD1

9.74e-05268816DOID:162 (implicated_via_orthology)
Diseaseidiopathic pulmonary fibrosis

PTPN14 KIF15 SPDL1

5.24e-0457813EFO_0000768
Diseasesusceptibility to childhood ear infection measurement

STK3 IFT81 KIF16B GALNT5

1.28e-03171814EFO_0007904
Diseasecolorectal cancer, hormone replacement therapy

LRPPRC SASH1 NDUFA10

1.85e-0388813EFO_0003961, MONDO_0005575
Diseaseurinary uromodulin measurement

TAF1B MELK DYNC1H1

2.37e-0396813EFO_0005663
DiseaseHIV-1 infection

SASH1 AOAH CCRL2

2.51e-0398813EFO_0000180
DiseaseMalignant neoplasm of breast

PTPN14 BRCA2 PPP1R12B SPTAN1 KIF16B PLA2G4A DDO GALNT5 PKDREJ

2.71e-031074819C0006142
Diseaseblood cobalt measurement

AOAH PIP4K2A FRMD1

2.74e-03101813EFO_0007577

Protein segments in the cluster

PeptideGeneStartEntry
PEKLTAFKEKYMEFD

AIF1L

46

Q9BQI0
EFVVYKPQMEDQKYK

CCRL2

166

O00421
PIDKYVFEKMEEKEA

CWC25

91

Q9NXE8
LFTLKEEKPKMYFMT

ARL6IP1

126

Q15041
KDLFSKSDPFMEIYK

CPNE6

166

O95741
DTKSPDYVSQEMVFK

KIF16B

66

Q96L93
SAVKNEEYFMFPEPK

MELK

431

Q14680
AKVKKSLPEMYAFTV

NPTX1

241

Q15818
MEQSVPFKDVDSDKY

AOAH

176

P28039
KFPKFVSKEMENMYI

CADPS

326

Q9ULU8
PESFLTRDKKKTNYM

KIF15

401

Q9NS87
TKQYKFKPEIMPDDS

RPGRIP1L

576

Q68CZ1
LTDSVKGKDEYFKNM

DST

2761

Q03001
KGKDEYFKNMTPKVD

DST

2766

Q03001
FEAKEETYKSLMQKG

DST

6536

Q03001
FKDLEATKSKTMIFY

CCDC178

651

Q5BJE1
SEKKMKYLSLFDVDP

FSIP2

1226

Q5CZC0
DPKFMQDVFTFYVKE

PCDH7

636

O60245
MSVFVKSYSKEEKFL

NRSN1

136

Q8IZ57
ADMQSKKRKSDFIPY

KIF1C

286

O43896
EYKFSPTDFLAKMEE

LRPPRC

176

P42704
FPDNYEKFMETKKAK

PPP4R3B

741

Q5MIZ7
KFNTKDEMPIFKLDY

DZIP3

376

Q86Y13
TFFPETTDIYDKKNM

IQGAP3

121

Q86VI3
KDAYTFPQEMKEKPK

HEMGN

446

Q9BXL5
KLPKQFKFAPEMDDY

MYBBP1A

341

Q9BQG0
YKKTFLPEMSEKCEV

NDUFA10

241

O95299
FRKMTEAELKKFPQY

DDO

116

Q99489
KPMVKDAFKDISIYF

PRDM9

21

Q9NQV7
KAFYKSFSKESDDPM

HSP90B1

356

P14625
IFMDLEQKLSKYFSK

FRMD1

106

Q8N878
VKFMPKEEKFYSQTL

HYDIN

1786

Q4G0P3
KFNLYMVTEKFPKEL

IFT81

271

Q8WYA0
PYMIFKEADATKNKE

DOCK7

361

Q96N67
KSKMFFKDIEEQYPT

BRCA2

1026

P51587
GKTEKEFKAYVSLFM

CHD3

1446

Q12873
PDQGKIFYSSIKEMK

GALNT5

61

Q7Z7M9
SDKKTEKTPVYMNFS

CCDC73

891

Q6ZRK6
NPFKEMFTQEEYKIL

C5orf22

261

Q49AR2
VIKEDSLMKDYFFKP

ADCY9

731

O60503
TESFVYEPKEQKKMF

IFI16

586

Q16666
GKEFTSKMDLEKPNY

DYNC1H1

3106

Q14204
KAKKDITFYMPVDNL

SPAM1

126

P38567
TTAYFFMKPKLGEKE

FMN2

1641

Q9NZ56
YQELAFMKPKDISSK

DNAH2

346

Q9P225
MKTDQLPFEKAYEKL

DUSP12

131

Q9UNI6
KVMYKEKDSDTQPRF

SDK2

1236

Q58EX2
EKIQDYEKMPESIKF

IL1R1

491

P14778
LMPDDFKAYSKIKVD

PIP4K2A

61

P48426
KGYFIFKLEKVMDDF

PPP4R2

46

Q9NY27
KFFMGTVVKKYEENP

PLA2G4A

371

P47712
NPKKFEDVFDEMIYF

MIGA1

426

Q8NAN2
KKVFYEKMEVAKPAD

RTP2

11

Q5QGT7
PSKFKKFYAEFESLM

RAPGEF4

886

Q8WZA2
KMKKNEVYETFSYPE

SCML1

121

Q9UN30
EADKSKPKFYVLSMF

LARS2

76

Q15031
PAKMAEKAKQIYEEF

RGS5

106

O15539
TFDPIAKMAKTVKYD

TAF1B

341

Q53T94
FFAPKMVSEKKIYDV

IQGAP2

81

Q13576
SKAKDEPEFFIDMLY

PKDREJ

2211

Q9NTG1
SPAKVAEVTKKFYSM

HMGCL

181

P35914
LMPDDFKAYSKIKVD

PIP4K2B

66

P78356
KPMVKDAFKDISIYF

PRDM7

21

Q9NQW5
EGMVFTEYEQIPKKK

PTPN14

906

Q15678
EKFKNLYDSMESKPS

SPDL1

341

Q96EA4
PQEMKALFKKKTYDE

SECISBP2

136

Q96T21
SKMPKADFYVLEKTG

TEFM

221

Q96QE5
LPKAFEEMYKVKFPE

TDRD7

361

Q8NHU6
EEMYKVKFPEDALKN

TDRD7

366

Q8NHU6
KKFYDDKVSALMQPS

TNS3

141

Q68CZ2
FPKATDMTFKAKLYD

MYH6

541

P13533
FMEELFKPQELYSKK

OSCP1

61

Q8WVF1
QEEQEFLSYKKPKMR

CLEC4E

121

Q9ULY5
FNAIETMPYVKKKAD

RRM2B

156

Q7LG56
PSFMDYFDKQDFKNK

STK3

391

Q13188
YDYQEKSPREVTMKK

SPTAN1

976

Q13813
KDPQFAEDYIFKAVM

XRN2

756

Q9H0D6
EKEYKVKINPSSMFD

PYGB

551

P11216
MDFLKYVVDKLNFKP

NRDC

871

O43847
PKKMGTFFSYPEEEK

SASH1

366

O94885
GPFMPDFKKEEKSYQ

UGT3A2

61

Q3SY77
MDFKLSKKEIVDPTY

ZPBP2

56

Q6X784
TKPELLDYKGKMFQF

ZMYM4

696

Q5VZL5
VPFSKVDEEQMKYKS

XRCC5

321

P13010
FFKNKEKMLYEEETP

PPP1R12B

331

O60237