Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncohesin loader activity

MAU2 NIPBL

3.29e-0521152GO:0061775
GeneOntologyMolecularFunctionbenzoate-CoA ligase activity

ACSM2A ACSM2B

9.83e-0531152GO:0018858
GeneOntologyMolecularFunctiondecanoate-CoA ligase activity

ACSM2A ACSM2B

1.96e-0441152GO:0102391
GeneOntologyMolecularFunctionhistone H2A deubiquitinase activity

USP16 BAP1

4.86e-0461152GO:0140950
GeneOntologyBiologicalProcesspositive regulation of cartilage development

SOX9 TAPT1 THRB PRKG2

4.39e-05361134GO:0061036
GeneOntologyBiologicalProcessmeiotic nuclear division

ANKRD31 SYCP2L TRIM75 RPS6KA2 BTBD18 TEX15 FANCA BRCA2

5.35e-052401138GO:0140013
GeneOntologyBiologicalProcessmale gamete generation

DRC7 CFAP47 SEMG1 SOX9 ARID4B BTBD18 TEX15 RNF17 FANCA ALMS1 BRCA2 ADGRG2 C2CD6 SPAG17

7.28e-0576211314GO:0048232
GeneOntologyBiologicalProcessgamete generation

DRC7 CFAP47 SEMG1 SOX9 ARID4B TRIM75 RPS6KA2 BTBD18 TEX15 RNF17 FANCA ALMS1 BRCA2 ADGRG2 C2CD6 SPAG17

8.91e-0598211316GO:0007276
GeneOntologyBiologicalProcessmeiotic cell cycle process

ANKRD31 SYCP2L TRIM75 RPS6KA2 BTBD18 TEX15 FANCA BRCA2

1.15e-042681138GO:1903046
GeneOntologyBiologicalProcessnuclear division

NUSAP1 ANKRD31 SYCP2L TRIM75 RPS6KA2 BTBD18 TEX15 USP16 FANCA BRCA2 NIPBL

1.18e-0451211311GO:0000280
GeneOntologyCellularComponentScc2-Scc4 cohesin loading complex

MAU2 NIPBL

3.11e-0521172GO:0090694
GeneOntologyCellularComponentSMC loading complex

MAU2 NIPBL

3.11e-0521172GO:0032116
HumanPhenoAbnormality of the male genitalia

CFAP47 SOX9 TAPT1 ADAMTS3 SPTBN1 ITGA6 TEX15 HMOX1 RFX7 BAP1 FANCA FOCAD GHR CEP120 ALMS1 BRCA2 ADGRG2 C2CD6 CHD6 SUZ12 PLEC CTNND2 SPAG17 CPLANE1 NIPBL

6.94e-0714373725HP:0010461
HumanPhenoDecreased fertility in males

CFAP47 SOX9 TEX15 HMOX1 FANCA ALMS1 BRCA2 ADGRG2 C2CD6 SPAG17

4.34e-062363710HP:0012041
HumanPhenoAbnormality of globe location

PPP1R21 SOX9 TAPT1 ADAMTS3 SPTBN1 BLNK WARS2 BAP1 FANCA FOCAD CEP120 THRB ALMS1 BRCA2 PGAP1 SUZ12 PLEC CTNND2 CAMTA1 CPLANE1 NIPBL

4.37e-0611223721HP:0100886
HumanPhenoAbnormality of globe location or size

PPP1R21 SOX9 TAPT1 ADAMTS3 SPTBN1 BLNK WARS2 BAP1 FANCA FOCAD CEP120 THRB ALMS1 BRCA2 PGAP1 CHD6 SUZ12 PLEC CTNND2 CAMTA1 CPLANE1 NIPBL

5.66e-0612463722HP:0000489
HumanPhenoAbnormal pinna morphology

PPP1R21 SOX9 TAPT1 ADAMTS3 SPTBN1 BLNK ITGA6 RFX7 WARS2 BAP1 FANCA CEP120 ALMS1 BRCA2 PGAP1 SUZ12 PRKG2 PLEC CTNND2 CAMTA1 CPLANE1 NIPBL

1.17e-0512993722HP:0000377
HumanPhenoFinger syndactyly

ADAMTS3 BAP1 FANCA BRCA2 SUZ12 PLEC CTNND2 CAMTA1 CPLANE1

1.78e-05218379HP:0006101
HumanPhenoAbnormality of the outer ear

PPP1R21 SOX9 TAPT1 ADAMTS3 SPTBN1 BLNK ITGA6 RFX7 WARS2 BAP1 FANCA CEP120 ALMS1 BRCA2 PGAP1 SUZ12 PRKG2 PLEC CTNND2 CAMTA1 CPLANE1 NIPBL

1.93e-0513373722HP:0000356
HumanPhenoSyndactyly

ADAMTS3 RFX7 BAP1 FANCA CEP120 BRCA2 SUZ12 PLEC CTNND2 CAMTA1 CPLANE1 NIPBL

2.16e-054173712HP:0001159
HumanPhenoIncomplete cleft of the upper lip

CEP120 CPLANE1

5.13e-052372HP:0011340
HumanPhenoAbnormal male external genitalia morphology

SOX9 TAPT1 ADAMTS3 SPTBN1 ITGA6 TEX15 RFX7 BAP1 FANCA FOCAD GHR CEP120 ALMS1 BRCA2 CHD6 SUZ12 PLEC CTNND2 SPAG17 CPLANE1 NIPBL

7.10e-0513293721HP:0000032
HumanPhenoAbnormal facial shape

PPP1R21 SOX9 TAPT1 ADAMTS3 SPTBN1 RFX7 WARS2 BAP1 FANCA FOCAD GHR CEP120 ALMS1 BRCA2 CHD6 SUZ12 PRKG2 CTNND2 CAMTA1 CPLANE1

7.36e-0512213720HP:0001999
HumanPhenoMale infertility

CFAP47 SOX9 TEX15 HMOX1 FANCA ADGRG2 C2CD6 SPAG17

9.69e-05209378HP:0003251
HumanPhenoAbnormal calvaria morphology

PPP1R21 SOX9 TAPT1 ADAMTS3 SPTBN1 RFX7 BAP1 FANCA FOCAD GHR CEP120 ALMS1 BRCA2 CHD6 SUZ12 PRKG2 PLEC CAMTA1 CPLANE1 NIPBL

1.10e-0412543720HP:0002683
HumanPhenoAbnormal external genitalia

SOX9 TAPT1 ADAMTS3 SPTBN1 ITGA6 TEX15 RFX7 BAP1 FANCA FOCAD GHR CEP120 ALMS1 BRCA2 CHD6 SUZ12 PLEC CTNND2 SPAG17 CPLANE1 NIPBL

1.18e-0413723721HP:0000811
HumanPhenoShort long bone

SOX9 TAPT1 FANCA GHR CEP120 BRCA2 PRKG2 CPLANE1 NIPBL

1.21e-04278379HP:0003026
HumanPhenoCongenital pyloric atresia

ITGA6 PLEC

1.53e-043372HP:0004399
HumanPhenoAbnormal eyelid morphology

PPP1R21 SOX9 TAPT1 ADAMTS3 SPTBN1 BLNK ITGA6 RFX7 BAP1 FANCA FOCAD GHR BRCA2 PGAP1 CHD6 SUZ12 PLEC CTNND2 CAMTA1 CPLANE1 NIPBL

1.76e-0414083721HP:0000492
HumanPhenoDecreased fertility

CFAP47 SOX9 TEX15 HMOX1 FANCA ALMS1 BRCA2 ADGRG2 C2CD6 SPAG17

2.65e-043803710HP:0000144
HumanPhenoAbnormal external nose morphology

PPP1R21 SOX9 TAPT1 ADAMTS3 SPTBN1 RFX7 BAP1 FOCAD GHR CEP120 CHD6 SUZ12 PLEC CAMTA1 CPLANE1 NIPBL

3.07e-049163716HP:0010938
HumanPhenoAbnormality of calvarial morphology

PPP1R21 SOX9 TAPT1 ADAMTS3 SPTBN1 RFX7 BAP1 FANCA FOCAD GHR CEP120 BRCA2 CHD6 SUZ12 PLEC CAMTA1 CPLANE1 NIPBL

3.49e-0411343718HP:0002648
HumanPhenoProtein-losing enteropathy

ADAMTS3 BLNK FOCAD

3.69e-0420373HP:0002243
HumanPhenoFrontal bossing

PPP1R21 SOX9 ADAMTS3 SPTBN1 RFX7 BAP1 FANCA FOCAD GHR BRCA2 CHD6 SUZ12 CAMTA1 CPLANE1

3.78e-047383714HP:0002007
HumanPhenoAbnormal shape of the frontal region

PPP1R21 SOX9 ADAMTS3 SPTBN1 RFX7 BAP1 FANCA FOCAD GHR BRCA2 CHD6 SUZ12 CAMTA1 CPLANE1

3.95e-047413714HP:0011218
HumanPhenoAbnormal frontal bone morphology

PPP1R21 SOX9 ADAMTS3 SPTBN1 RFX7 BAP1 FANCA FOCAD GHR BRCA2 CHD6 SUZ12 CAMTA1 CPLANE1

4.01e-047423714HP:0430000
DomainHEAT_REPEAT

HEATR4 TEX10 MROH7 HEATR5B NIPBL ARMC8

3.90e-06701126PS50077
DomainARM-type_fold

HEATR4 UBR4 TEX10 WDFY4 FOCAD DOCK5 MROH7 CTNND2 HEATR5B NIPBL ARMC8

6.14e-0633911211IPR016024
Domain-

HEATR4 TEX10 WDFY4 MROH7 CTNND2 HEATR5B NIPBL ARMC8

5.79e-0522211281.25.10.10
DomainARM-like

HEATR4 TEX10 WDFY4 MROH7 CTNND2 HEATR5B NIPBL ARMC8

2.24e-042701128IPR011989
DomainAMP-bd_C

ACSM2A ACSM2B

4.57e-03171122IPR025110
DomainAMP-binding_C

ACSM2A ACSM2B

4.57e-03171122PF13193
DomainHEAT

HEATR4 TEX10 NIPBL

5.10e-03581123IPR000357
DomainPA

RNF128 RNF133

5.70e-03191122PF02225
DomainPA_domain

RNF128 RNF133

5.70e-03191122IPR003137
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TPP2 CACNB1 UACA RPS6KA2 KTN1 SPTBN1 UBR4 TEX10 CLIP1 CEP170 SLC7A3 SPHKAP CTNND2 NIPBL ARMC8 ANKS1A

1.76e-079631181628671696
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ARID4B UACA SPTBN1 PARG RFX7 USP16 CLIP1 BAP1 IWS1 SUZ12 PLEC NIPBL ANKS1A

2.42e-067741181315302935
Pubmed

Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models.

SOX9 TEX15 BRCA2 TET1

4.21e-0632118427739607
Pubmed

RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain.

KTN1 CEP170 ANKS1A

4.49e-0610118329097665
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

SOX9 ZSWIM8 DIS3L SPTBN1 UBR4 ZNF521 MYNN USP16 FOCAD CLK1 CHD6 PLEC CTNND2 ST18 NIPBL ARMC8

7.41e-0612851181635914814
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

NUSAP1 PRUNE2 TPP2 SNX24 KTN1 SPTBN1 CAPN2 UBR4 COPS3 ZZEF1 CLIP1 EIF6 IWS1 ABCE1 PLEC KIF13A ANKS1A

8.61e-0614551181722863883
Pubmed

Nuclear factor of activated T cells 5 deficiency increases the severity of neuronal cell death in ischemic injury.

SLC5A3 NFAT5

1.14e-052118223172129
Pubmed

Binding of integrin alpha6beta4 to plectin prevents plectin association with F-actin but does not interfere with intermediate filament binding.

ITGA6 PLEC

1.14e-052118210525545
Pubmed

Genetic variants in fanconi anemia pathway genes BRCA2 and FANCA predict melanoma survival.

FANCA BRCA2

1.14e-052118225243787
Pubmed

Isolated NIBPL missense mutations that cause Cornelia de Lange syndrome alter MAU2 interaction.

MAU2 NIPBL

1.14e-052118221934712
Pubmed

Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.

ACSM2A ACSM2B

1.14e-052118219634011
Pubmed

Genome-wide analysis identifies a functional association of Tet1 and Polycomb repressive complex 2 in mouse embryonic stem cells.

TET1 SUZ12

1.14e-052118223987249
Pubmed

Structural and functional analysis of the actin binding domain of plectin suggests alternative mechanisms for binding to F-actin and integrin beta4.

ITGA6 PLEC

1.14e-052118212791251
Pubmed

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.

ACSM2A ACSM2B

1.14e-052118216521160
Pubmed

Localisation of the SMC loading complex Nipbl/Mau2 during mammalian meiotic prophase I.

MAU2 NIPBL

1.14e-052118224287868
Pubmed

Tie2-dependent deletion of α6 integrin subunit in mice reduces tumor growth and angiogenesis.

ITGA6 TEK

1.14e-052118225176420
Pubmed

Tie2-dependent knockout of α6 integrin subunit in mice reduces post-ischaemic angiogenesis.

ITGA6 TEK

1.14e-052118222517984
Pubmed

Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.

ACSM2A ACSM2B

1.14e-052118229948332
Pubmed

Alterations of the Primary Cilia Gene SPAG17 and SOX9 Locus Noncoding RNAs Identified by RNA-Sequencing Analysis in Patients With Systemic Sclerosis.

SOX9 SPAG17

1.14e-052118235762854
Pubmed

MAU2 and NIPBL Variants Impair the Heterodimerization of the Cohesin Loader Subunits and Cause Cornelia de Lange Syndrome.

MAU2 NIPBL

1.14e-052118232433956
Pubmed

BRCA2 interacts with the cytoskeletal linker protein plectin to form a complex controlling centrosome localization.

BRCA2 PLEC

1.14e-052118219709076
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

UBR4 RB1CC1 BAP1 ALMS1 BRCA2 TET1 CHD6 CRYBG3 PLEC

1.35e-05418118934709266
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TPP2 ZSWIM8 DDX31 SPTBN1 UBR4 TEX10 EIF6 CEP170 ABCE1 PLEC NIPBL

1.46e-056531181122586326
Pubmed

Human transcription factor protein interaction networks.

NUSAP1 SOX9 DDX31 ARID4B DIS3L SPTBN1 UBR4 ZNF521 RFX7 TEX10 EIF6 BAP1 RPL7L1 ALMS1 CHD6 NIPBL

2.72e-0514291181635140242
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

TRIM75 RB1CC1 USP16 IWS1 ALMS1 CHD6 SUZ12 ARMC8 ANKS1A

3.34e-05469118927634302
Pubmed

The FANC/BRCA Pathway Releases Replication Blockades by Eliminating DNA Interstrand Cross-Links.

FANCA BRCA2

3.42e-053118232466131
Pubmed

TonEBP Suppresses the HO-1 Gene by Blocking Recruitment of Nrf2 to Its Promoter.

HMOX1 NFAT5

3.42e-053118231057560
Pubmed

Plectin isoform-dependent regulation of keratin-integrin alpha6beta4 anchorage via Ca2+/calmodulin.

ITGA6 PLEC

3.42e-053118219419971
Pubmed

Fusion of PRKG2 and SPTBN1 to the platelet-derived growth factor receptor beta gene (PDGFRB) in imatinib-responsive atypical myeloproliferative disorders.

SPTBN1 PRKG2

3.42e-053118218262053
Pubmed

Novel transglutaminase-like peptidase and C2 domains elucidate the structure, biogenesis and evolution of the ciliary compartment.

DRC7 CC2D2B

3.42e-053118222983010
Pubmed

Structural basis of the interaction between integrin alpha6beta4 and plectin at the hemidesmosomes.

ITGA6 PLEC

3.42e-053118219242489
Pubmed

Immunohistochemical Evaluation of BAP1 Expression in Breast Cancer with Known BRCA1 and BRCA2 Mutations and Comparison with Histopathological Features.

BAP1 BRCA2

3.42e-053118235261270
Pubmed

Epidermolysis Bullosa with Pyloric Atresia

ITGA6 PLEC

3.42e-053118220301336
Pubmed

The Fanconi Anemia Pathway Protects Genome Integrity from R-loops.

FANCA BRCA2

3.42e-053118226584049
Pubmed

Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage.

MAU2 NIPBL

3.42e-053118228167679
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RPS6KA2 SPTBN1 CCDC18 RFX7 CEP170 VPS13D ALMS1 TET1 CRYBG3 PLEC KIF13A ANKS1A

3.80e-058611181236931259
Pubmed

A human MAP kinase interactome.

ARID4B KTN1 SPTBN1 MYNN BICRAL CHD6 PLEC MAPK6 CPLANE1

4.39e-05486118920936779
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

NUSAP1 SUMO4 ARID4B UBR4 MAU2 TIMMDC1 USP16 BAP1 IWS1 SLC7A3 THRB SUZ12 MAPK6 NIPBL ANKS1A

4.45e-0513271181532694731
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

ARID4B FSIP1 SPTBN1 VPS13D CHD6 PLEC SPINDOC

4.68e-05277118730745168
Pubmed

Global phosphoproteome of HT-29 human colon adenocarcinoma cells.

SPTBN1 CLIP1 CEP170 PLEC

4.96e-0559118416083285
Pubmed

p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas.

SOX9 ITGA6 CTNND2

6.42e-0523118325523391
Pubmed

Neural crest cell-specific inactivation of Nipbl or Mau2 during mouse development results in a late onset of craniofacial defects.

MAU2 NIPBL

6.82e-054118224700590
Pubmed

MCM2-7-dependent cohesin loading during S phase promotes sister-chromatid cohesion.

MAU2 NIPBL

6.82e-054118229611806
Pubmed

ZFP521 contributes to pre-B-cell lymphomagenesis through modulation of the pre-B-cell receptor signaling pathway.

BLNK ZNF521

6.82e-054118226522721
Pubmed

Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance.

MAU2 NIPBL

6.82e-054118216802858
Pubmed

Genetic enhancement of limb defects in a mouse model of Cornelia de Lange syndrome.

SOX9 NIPBL

6.82e-054118227120109
Pubmed

Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1.

FANCA BRCA2

6.82e-054118216859999
Pubmed

TET1 Directs Chondrogenic Differentiation by Regulating SOX9 Dependent Activation of Col2a1 and Acan In Vitro.

SOX9 TET1

6.82e-054118233134768
Pubmed

Expression of Acsm2, a kidney-specific gene, parallels the function and maturation of proximal tubular cells.

ACSM2A ACSM2B

6.82e-054118232830538
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

NUSAP1 SUMO4 ARID4B PARG CCDC18 IWS1 CEP170 ALMS1 CHD6 SUZ12

7.27e-056451181025281560
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

NUSAP1 SPTBN1 WDFY4 SLC7A3 ABCE1 PGAP1 TET1 PLEC CAMTA1 CPLANE1 KIF13A NFAT5 ARMC8

8.26e-0510841181311544199
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

UACA VPS13D ALMS1 BICRAL NFAT5

8.43e-05130118512421765
Pubmed

Variants in the GH-IGF axis confer susceptibility to lung cancer.

GHR BRCA2

1.13e-045118216741161
Pubmed

Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2.

FANCA BRCA2

1.13e-045118216621732
Pubmed

BRCA-deficient metastatic prostate cancer has an adverse prognosis and distinct genomic phenotype.

FANCA BRCA2

1.13e-045118237549632
Pubmed

CXCL12-CXCR4 Interplay Facilitates Palatal Osteogenesis in Mice.

SOX9 HMOX1

1.13e-045118232974338
Pubmed

PCNA recruits cohesin loader Scc2 to ensure sister chromatid cohesion.

MAU2 NIPBL

1.13e-045118237592094
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PRUNE2 BAP1 ALMS1 CHD6 CAMTA1 DAGLA

1.24e-04225118612168954
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

NUSAP1 ARID4B KTN1 MAU2 RFX7 EIF6 BAP1 IWS1 FANCA DOCK5 RPL7L1 CHD6 SUZ12 NIPBL

1.29e-0412941181430804502
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DDX31 STBD1 TAPT1 UACA KTN1 SPTBN1 UBR4 CCDC18 RB1CC1 TIMMDC1 USP16 EIF6 SLC5A3 RPL7L1 CRYBG3

1.58e-0414871181533957083
Pubmed

Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture.

KTN1 CEP170 MAPK6

1.60e-0431118322261722
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

NUSAP1 SUMO4 DDX31 UACA KTN1 TEX10 EIF6 IWS1 RPL7L1 CHD6 SUZ12 CTNND2 HEATR5B NIPBL ARMC8

1.69e-0414971181531527615
Pubmed

FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3.

FANCA BRCA2

1.70e-046118218212739
Pubmed

The E3 ubiquitin ligase GREUL1 anteriorizes ectoderm during Xenopus development.

RNF128 RNF133

1.70e-046118212435366
Pubmed

In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex.

MAU2 NIPBL

1.70e-046118222628566
Pubmed

Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance.

FANCA BRCA2

1.70e-046118220450923
Pubmed

Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.

RB1CC1 BAP1 BICRAL ANKS1A

1.88e-048311849039502
Pubmed

Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.

MAU2 DSN1 SUZ12 NIPBL

1.88e-0483118420562864
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZSWIM8 UBR4 RB1CC1 BICRAL

2.26e-0487118412465718
Pubmed

The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome.

ITGA6 PLEC

2.37e-047118210637308
Pubmed

Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production.

GHR THRB

2.37e-047118228591635
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

NUSAP1 SOX9 DDX31 ARID4B BAP1 IWS1 CHD6 SUZ12 NIPBL

2.37e-04608118936089195
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

PPP1R21 SPTBN1 RNF17 CLIP1 EIF6 DOCK5 BRCA2 CHD6 KIF13A ANKS1A

2.57e-047541181035906200
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

UACA RPS6KA2 RB1CC1 TEX10 EIF6 CEP170 CLK1 ABCE1 PLEC MAPK6 CPLANE1

2.79e-049101181136736316
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PRUNE2 UACA DIS3L KTN1 WDFY4 CEP170 VPS13D ALMS1

2.89e-04493118815368895
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

PRUNE2 ECM2 FANCA DOCK5 CLK1 MROH7 PLEC MAPK6

3.01e-04496118831343991
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

UACA KTN1 SPTBN1 CLIP1 CEP170 ALMS1 CLK1 PLEC

3.05e-04497118823414517
Pubmed

Spatacsin regulates directionality of lysosome trafficking by promoting the degradation of its partner AP5Z1.

UBR4 KIF13A

3.15e-048118237871017
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

SPTBN1 UBR4 MAU2 PLEC SPINDOC NIPBL

3.43e-04272118631010829
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ZSWIM8 MAU2 CAMTA1 NFAT5

3.84e-04100118410048485
Pubmed

Proteome-wide analysis of phospho-regulated PDZ domain interactions.

RPS6KA2 CTNND2 HEATR5B

3.97e-0442118330126976
Pubmed

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

UACA KTN1 UBR4 CEP170 PLEC

4.03e-04182118531067453
Pubmed

Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression.

MAU2 NIPBL

4.05e-049118216682347
Pubmed

Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.

ITGA6 PLEC

4.05e-049118212482924
Pubmed

Conserved overlapping gene arrangement, restricted expression, and biochemical activities of DNA polymerase ν (POLN).

FANCA BRCA2

4.05e-049118226269593
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

CAPN2 UBR4 COPS3 TEX10 CHD6 ARMC8

4.16e-04282118623667531
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SEMG1 ZSWIM8 ARID4B UACA DIS3L BTBD18 ZZEF1 CEP170 ALMS1 BICRAL SUZ12 CRYBG3

4.23e-0411161181231753913
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FOCAD SPHKAP CHD6 SUZ12 CAMTA1 NFAT5 ST18

4.94e-04407118712693553
Pubmed

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.

ARID4B TET1

5.05e-0410118221490601
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

SPTBN1 UBR4 RB1CC1 CEP170 PLEC MAPK6 SPINDOC ARMC8

6.02e-04551118834728620
Pubmed

The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.

ITGA6 PLEC

6.15e-0411118210811835
Pubmed

Bimodal regulation of the PRC2 complex by USP7 underlies tumorigenesis.

SPTBN1 SUZ12

6.15e-0411118233849069
Pubmed

Interaction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus.

ITGA6 PLEC

6.15e-0411118212802069
Pubmed

Variants in LRRC7 lead to intellectual disability, autism, aggression and abnormal eating behaviors.

SPTBN1 CTNND2

6.15e-0411118239256359
Pubmed

Current insights into the formation and breakdown of hemidesmosomes.

ITGA6 PLEC

6.15e-0411118216757171
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

PRUNE2 STBD1 UBR4 MAU2 DOCK5 PLEC CAMTA1

6.83e-04430118735044719
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

NUSAP1 SOX9 CAPN2 UBR4 MAU2 TEX10 IWS1 ABCE1 SUZ12 PLEC NIPBL

6.87e-0410141181132416067
Pubmed

Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo.

NUSAP1 PPP1R21 SPTBN1 TEX15 IWS1 CLK1 BICRAL

7.02e-0443211877671812
Pubmed

Lhx2 in germ cells suppresses endothelial cell migration in the developing ovary.

SOX9 TEK

7.37e-0412118235337816
Pubmed

Foxa2 and Pdx1 cooperatively regulate postnatal maturation of pancreatic β-cells.

SOX9 ITGA6

7.37e-0412118228580283
InteractionMLF1 interactions

COPS3 DSN1 ALMS1 BRCA2 CRYBG3 PLEC HEATR5B

3.84e-061131157int:MLF1
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SOX9 RPS6KA2 PARG ITGA6 RB1CC1 ZZEF1 CLIP1 CEP170 BRCA2 ABCE1 BICRAL SUZ12 CRYBG3 MAPK6 NIPBL ANKS1A

1.35e-0685611716M4500
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

NUSAP1 ARID4B KTN1 ITGA6 RB1CC1 CLIP1 IWS1 CEP170 SUZ12 CTNND2 MAPK6 CPLANE1 NIPBL

7.66e-0665611713M18979
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

ZDHHC2 TPP2 KTN1 PARG CCDC18 RFX7 USP16 IWS1 ALMS1 BRCA2 SUZ12 CTNND2 NIPBL

4.68e-0653211213Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

NUSAP1 KTN1 CCDC18 CLIP1 IWS1 ALMS1 BRCA2 NIPBL

8.23e-061921128Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500

ZDHHC2 NUSAP1 SYCP2L KTN1 CCDC18 CLIP1 IWS1 ALMS1 BRCA2 CTNND2 ST18 NIPBL

1.28e-0549811212Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

NUSAP1 TPP2 SOX9 ARID4B KTN1 TEX10 USP16 CLIP1 IWS1 SLC5A3 CEP120 ALMS1 BRCA2 TET1 SUZ12 MAPK6 CPLANE1 RNF128 NIPBL

2.99e-05125711219facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

NUSAP1 UACA PARG CCDC18 RFX7 IWS1 ALMS1 BRCA2 TET1 HEATR5B NIPBL

3.84e-0546911211Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

NUSAP1 TPP2 SOX9 SYCP2L ARID4B KTN1 TEX10 USP16 CLIP1 IWS1 SLC5A3 CEP120 ALMS1 BRCA2 TET1 SUZ12 MAPK6 CPLANE1 RNF128 NIPBL

7.11e-05145911220facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000

SPTBN1 ITGA6 MAU2 TEX15 RNF17 SLC5A3 FOCAD ADGRG2 SLC37A2 CAPS2 PLEC CAMTA1 CPLANE1 NFAT5

7.62e-0579511214gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlasdev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_500

CCDC18 TEX15 RNF17 BRCA2

8.46e-05441124gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k4_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

NUSAP1 ARID4B KTN1 CCDC18 CLIP1 IWS1 CEP170 BRCA2 CLK1 TET1 HEATR5B NIPBL

1.22e-0462911212Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000

FSIP1 PARG CCDC18 TEX10 RNF17 DSN1 BRCA2 PGAP1 CPLANE1

1.27e-043611129gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

PPP1R21 DIS3L CLIP1 IWS1 BRCA2 HEATR5B CPLANE1 NIPBL

1.57e-042911128Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#4_top-relative-expression-ranked_500

CCDC18 TEX10 RNF17 PGAP1 TET1

1.98e-041011125gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k4_500
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_500

SPTBN1 ITGA6 TEX15 RNF17 ADGRG2 SLC37A2 CAPS2 CPLANE1 NFAT5

2.13e-043871129gudmap_developingGonad_e16.5_ovary_500
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#2_top-relative-expression-ranked_500

CCDC18 TEX15 RNF17 BRCA2

2.18e-04561124gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k2_500
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000

SPTBN1 CCDC18 ITGA6 TEX15 RB1CC1 RNF17 SLC5A3 ALMS1 BRCA2 SLC37A2 CAPS2 CPLANE1 NFAT5

2.28e-0477611213gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000

SPTBN1 ITGA6 TEX15 RB1CC1 RNF17 SLC5A3 ADGRG2 SLC37A2 CAPS2 PLEC CAMTA1 CPLANE1 NFAT5

2.33e-0477811213gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

NUSAP1 ARID4B CCDC18 CLIP1 IWS1 ALMS1 BRCA2 NIPBL

2.46e-043111128Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

NUSAP1 DIS3L CCDC18 FANCA BRCA2 CHD6 SUZ12

3.32e-042461127Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K3
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_1000

TAPT1 DOCK5 CRYBG3 KIF13A DAGLA

3.47e-041141125gudmap_kidney_P3_CapMes_Crym_k2_1000
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_1000

ITGA6 TEX15 RB1CC1 RNF17 SLC37A2 CAPS2

3.77e-041791126gudmap_developingGonad_e14.5_ ovary_1000_k5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

ZDHHC2 NUSAP1 PPP1R21 KTN1 MYNN RB1CC1 CLIP1 IWS1 ALMS1 BRCA2 PGAP1 CTNND2 NIPBL

4.39e-0483111213Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#1

ZDHHC2 UACA KTN1 ALMS1 TET1 CTNND2 NIPBL

4.52e-042591127Facebase_RNAseq_e8.5_Floor Plate_1000_K1
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

CCDC18 RB1CC1 USP16 EIF6 IWS1 CEP170 VPS13D SUZ12 NIPBL

3.05e-09198118976d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

ARID4B UACA KTN1 RB1CC1 USP16 CLIP1 VPS13D SPAG17 NIPBL

3.19e-09199118961b1ed2db71b96157b92b7535d1955a4033098da
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

ARID4B KTN1 RB1CC1 USP16 CLIP1 EIF6 IWS1 SUZ12 NIPBL

3.19e-091991189fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

ARID4B KTN1 RB1CC1 USP16 CLIP1 EIF6 IWS1 NIPBL

6.14e-08199118853ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

UACA KTN1 SPTBN1 ZNF521 ITGA6 TEK NIPBL

1.07e-062001187dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 CEP120 ALMS1 BRCA2 ADGRG2 SPAG17

3.92e-061571186410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NUSAP1 CCDC18 WDFY4 FANCA BRCA2 RAB7B

7.30e-061751186f7d191cde68de8f3457fa62b1df53b6d0dbe5001
ToppCellILEUM-non-inflamed-(7)_Lymphatics|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

UACA SPTBN1 ZNF521 DOCK5 ACSM2B ANKS1A

8.31e-06179118699777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 FSIP1 CCDC18 CAPS2 SPAG17 RNF128

8.58e-0618011865c9d2d44d840cd4ec7d42d43446ba2b689e7ec43
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 FSIP1 CCDC18 CAPS2 SPAG17 RNF128

8.58e-061801186c60e74fbbd815a0251253a19dc520a254b2e1762
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KTN1 SPTBN1 CLIP1 PGAP1 RAB7B NIPBL

9.13e-061821186f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KTN1 SPTBN1 PARG CLIP1 RAB7B NIPBL

9.72e-0618411861154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA SPTBN1 ZNF521 TEK CTNND2 KIF13A

1.17e-051901186474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDHHC2 PRUNE2 RPS6KA2 GHR SPHKAP ST18

1.20e-051911186f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2 KIF13A

1.27e-051931186aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2 KIF13A

1.27e-051931186c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RPS6KA2 SPTBN1 ZNF521 DOCK5 ACSM2B ANKS1A

1.27e-051931186bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UACA KTN1 CCDC18 BLNK SUZ12 NIPBL

1.31e-0519411868ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UACA RPS6KA2 SPTBN1 ZNF521 ITGA6 TEK

1.39e-051961186629236f95c838a473b5964a49b7c1b7ad863ea12
ToppCellsevere-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NUSAP1 DIS3L C4orf50 DSN1 BRCA2 SUZ12

1.43e-05197118670704b149b2820b8601d2495b7cd9cbe91eda262
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

KTN1 RB1CC1 USP16 EIF6 IWS1 NIPBL

1.52e-05199118619674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

KTN1 RB1CC1 USP16 CLIP1 EIF6 NIPBL

1.52e-051991186c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Vein|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

KTN1 ZNF521 ITGA6 TEK PGAP1 PLEC

1.56e-0520011867eb366b2c5394af7c77650bde6261e7dac67154e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

PPP1R21 PRUNE2 DDX31 WARS2 BAP1 ANKS1A

1.56e-0520011866b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

UACA RPS6KA2 SPTBN1 ZNF521 ITGA6 TEK

1.56e-052001186a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCellLPS_IL1RA_TNF-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

UACA RPS6KA2 SPTBN1 ZNF521 ITGA6 TEK

1.56e-052001186d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCellLPS-IL1RA-Endothelial-Epi-like-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB1 STBD1 UACA HEATR4 SPTBN1

3.34e-0513811855f8ac8f67e34a7cf560099208e6884102532391e
ToppCellCV-Healthy-3|Healthy / Virus stimulation, Condition and Cluster

ANKRD31 ZSWIM8 BAP1 CCDC7 CRYBG3

5.64e-05154118526bf81a86700db7e65c2384ffe94ed4253ea4047
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 FSIP1 ALMS1 C2CD6 NFAT5

5.82e-051551185441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN1 TEK RNF17 CCDC7 SPHKAP

5.82e-0515511858fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NUSAP1 BLNK RNF17 BRCA2 MAPK6

6.18e-0515711856730b775308f45a2f3946016bdbb7f8e5b5efe49
ToppCellPND01-03-samps-Myeloid-Macrophage-CD163+_Macrophage|PND01-03-samps / Age Group, Lineage, Cell class and subclass

PRUNE2 HMOX1 WDFY4 RAB7B SLC37A2

6.76e-0516011854480a7d6bd48d06b4e5196faac868f31ab7ed3ad
ToppCellICU-SEP-Myeloid-cDC1|ICU-SEP / Disease, Lineage and Cell Type

RPS6KA2 WDFY4 TET1 RAB7B ST18

6.96e-0516111859fb73909fc2ec99f96ca2eed1a053bce89de7d16
ToppCellCV-Healthy-3|CV / Virus stimulation, Condition and Cluster

ANKRD31 ZSWIM8 BAP1 CCDC7 CRYBG3

6.96e-051611185fd4a79385ea967b9900dc76a3add813b894a3a28
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNX24 BLNK THRB RAB7B ST18

7.82e-0516511856dda1c7fd812792bd2e4fb1a7ccb82a3552b0a3b
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WDFY4 RAB7B C2CD6 CTNND2 ST18

8.05e-051661185b1bebcbe17386cb102b11d551e62d46156ce0c68
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

WDFY4 RAB7B C2CD6 CTNND2 ST18

8.28e-051671185e44743b20a7435c579d8e999ddc4ca119d6753f2
ToppCell3'-Adult-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX9 ITGA6 SLC5A3 PGAP1 CAMTA1

8.51e-051681185b08458164d270d625b8ee390122d1c2ce8c653db
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDHHC2 TPP2 COPS3 CRYBG3 CPLANE1

8.51e-051681185d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NUSAP1 CCDC18 WDFY4 FANCA BRCA2

8.75e-05169118554b13ab02b4c187f4754045ecfcf409749e7ccc0
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|390C / Donor, Lineage, Cell class and subclass (all cells)

HMOX1 RAB7B SLC37A2 ST18 DAGLA

9.00e-0517011853a7121d045f9ae54583b0f5f7436abf3665a1bce
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Uncommitted_AE_cell|E16.5-samps / Age Group, Lineage, Cell class and subclass

SOX9 SNX24 CCDC7 CTNND2 MAPK6

9.00e-0517011855a64e05c263df915085988d881808221e2c0f2e2
ToppCellCiliated_cells-A-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

PRUNE2 SOX9 FSIP1 CCDC110 SPAG17

9.00e-0517011853d3a03979014df3a05c49be18010c6b94d786707
ToppCellfacs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l12|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 BLNK HMOX1 RAB7B SLC37A2

9.25e-05171118526755e43d94e934106fc19ab929e4d34c17d6cba
ToppCellfacs-Marrow-KLS-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STBD1 MRGPRD WDFY4 RAB7B CTNND2

9.51e-051721185979fd7b435f59b8a4d290a809cf76147d4c63d48
ToppCellfacs-Marrow-KLS-18m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STBD1 MRGPRD WDFY4 RAB7B CTNND2

9.51e-051721185f4d7f416802218ce56408fa4cb8a555d846bc85b
ToppCellBac-SEP-Myeloid-cDC1|Bac-SEP / Disease, Lineage and Cell Type

WDFY4 THRB ADGRG2 RAB7B CTNND2

9.77e-051731185f88269327441858ddb8c49b9dd619b76fd53b1da
ToppCelldroplet-Lung-nan-21m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNX24 BLNK RNF17 RAB7B SLC37A2

9.77e-05173118531ea04e65876c42b90245d280f0b6439bfffbace
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNX24 BLNK RAB7B SLC37A2 CTNND2

9.77e-05173118526bba58f9fb215d1d155504906cd77e8774f6936
ToppCelldroplet-Lung-LUNG-1m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNX24 BLNK RAB7B SLC37A2 CTNND2

9.77e-05173118569b404e92aad3e6dff67e75466f073f20a71f13f
ToppCelldroplet-Lung-nan-21m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNX24 BLNK RNF17 RAB7B SLC37A2

9.77e-0517311851cff815536f620e32b9805666e1aa711462c2d25
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

CAPN2 CLIP1 SLC37A2 CRYBG3 MAPK6

1.03e-0417511850cc215109d9915af47e4d0a120ce2e46910715fa
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

NUSAP1 CACNB1 CCDC18 BAP1 DAGLA

1.03e-041751185bde785ff0c854646d7ab8571359e9d69a7bf013f
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS6KA2 TEK CEP170 ADGRG2 ST18

1.03e-041751185f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 CCDC18 ALMS1 SPAG17 RNF128

1.06e-041761185d6d7e4e937d49a5c0d16322c8dd3bf9e97eb8732
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 CCDC18 ALMS1 SPAG17 RNF128

1.06e-041761185c03d80df2550c0d2b0452326480d6bf21d20fdd2
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX9 CRACR2A HEATR4 SLC5A3 ANKS1A

1.09e-041771185e1e45956887371b1c18f1eb479dd930031497520
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NUSAP1 SOX9 SNX24 CCDC18 TEX15

1.09e-0417711853081ce5fc66a1bb833719d6c0e0a6fc7115eeb91
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS3 ECM2 ALMS1 ADGRG2 CTNND2

1.18e-041801185d33bb00f2b7d07dda9015cb8eafd742c2b2e9ace
ToppCellfacs|World / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 SPTBN1 ITGA6 RAB7B PLEC

1.24e-04182118508f775135b451be709f5fc8e1cbcf63425794a2e
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

ADAMTS3 ECM2 TEK GHR CRYBG3

1.30e-04184118567164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellILEUM-inflamed-(7)_Lymphatics|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

UACA SPTBN1 ZNF521 DOCK5 ACSM2B

1.34e-041851185d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KTN1 SPTBN1 CLIP1 RAB7B NIPBL

1.34e-0418511857adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS6KA2 KTN1 SPTBN1 TEK RAB7B

1.37e-0418611850ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell10x5'-Liver-Myeloid_Dendritic-DC1|Liver / Manually curated celltypes from each tissue

SYCP2L WDFY4 RAB7B CRYBG3 ST18

1.37e-041861185e823529ffd06352c6bdec102f221fdf27f7c7369
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

ARID4B IWS1 VPS13D ALMS1 NFAT5

1.37e-04186118503db813598b67b1e08f759758a1c2023396921fa
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARID4B HMOX1 CLIP1 CLK1 NIPBL

1.41e-041871185663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UACA RPS6KA2 SPTBN1 ITGA6 TEK

1.41e-0418711850ef82111b9049cc7ee78d64d240e1f10ab14d6b6
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NUSAP1 DRC7 SPTBN1 ITGA6 TEK

1.44e-0418811855d166d9e71632edd059ff0a9f66f8763f259d40a
ToppCellLPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2

1.44e-041881185789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic|lymph-node_spleen / Manually curated celltypes from each tissue

NUSAP1 TEX15 WDFY4 RAB7B ST18

1.44e-041881185723348a1836a074e068320cb736ce6a953e0038f
ToppCellLPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2

1.48e-041891185e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2

1.48e-0418911855d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PRUNE2 DOCK5 ACSM2A ACSM2B ANKS1A

1.52e-0419011859ce301841ce9486701fa28eb2a9929e35d476878
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2

1.52e-041901185a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NUSAP1 CCDC18 FANCA BRCA2 SUZ12

1.52e-041901185d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2

1.52e-041901185106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPTBN1 ZNF521 DOCK5 ACSM2A ACSM2B

1.55e-041911185361b123c8289015206d5e706ab2c615d9a724179
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPTBN1 ZNF521 DOCK5 ACSM2A ACSM2B

1.55e-041911185011dc22c488369734749e839d65d52fe46b6a1a4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NUSAP1 CCDC18 WDFY4 BRCA2 RAB7B

1.55e-041911185ff2cc4c10aa584b3daeaaf23cd8ee09bdbdf684d
ToppCellfacs-Pancreas|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 RPS6KA2 SPHKAP CTNND2 ST18

1.55e-041911185d48e5f67d384226add7d7fb2a124954136e09a82
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ARID4B RB1CC1 CHD6 NFAT5 NIPBL

1.59e-041921185916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KTN1 BLNK ITGA6 CLIP1 NFAT5

1.59e-041921185f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2

1.59e-04192118504f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2

1.59e-041921185c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2

1.63e-041931185e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellVE-mDC1-|VE / Condition, Cell_class and T cell subcluster

HMOX1 WDFY4 THRB RAB7B ST18

1.63e-0419311855df6033bc0e4f96a20d526486a8e89c990e21831
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2

1.63e-04193118502f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2

1.63e-0419311856e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2

1.63e-041931185af5108260783e69a7d67896c5bf64f862525926d
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)|Adult / Lineage, Cell type, age group and donor

SYCP2L UACA SPTBN1 ITGA6 TEK

1.63e-04193118539c6c96a2a100b1b290a779d36cc6bc17245720b
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2

1.63e-041931185e1d546165dcc2392f540162206852c4717d7306f
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2

1.63e-0419311855122b1ffba42de190061be34ecdc6176f84e56a3
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NUSAP1 CCDC18 DSN1 FANCA BRCA2

1.63e-0419311854b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellVE-mDC1|VE / Condition, Cell_class and T cell subcluster

HMOX1 WDFY4 THRB RAB7B ST18

1.63e-04193118512b2708db9db8b88365b8ebeb4908f28c50081bb
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ARID4B RB1CC1 CHD6 NFAT5 NIPBL

1.63e-041931185e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NUSAP1 ITGA6 TEK ACSM2A ACSM2B

1.63e-0419311851b69f92c6a7a2516e393d3f3c371407ec791343d
ToppCellmoderate-Epithelial-FOXN4+|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPTBN1 CEP120 ALMS1 BRCA2 CPLANE1

1.67e-0419411855dffa578149104dda33774361e9e77b227b5f1ce
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

SYCP2L UACA SPTBN1 ITGA6 TEK

1.67e-04194118571ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA ZNF521 ITGA6 TEK CTNND2

1.67e-04194118543f92b0533e26633dc94cce554045d641ef8fd76
DiseaseX-21319 measurement

ACSM2A ACSM2B

1.48e-0521142EFO_0800807
DiseaseAbnormality of the respiratory system

PPP1R21 SUZ12

1.48e-0521142C4018871
DiseaseX-11478 measurement

ACSM2A ACSM2B

4.43e-0531142EFO_0021242
DiseaseEpidermolysis bullosa with pyloric atresia

ITGA6 PLEC

4.43e-0531142C1856934
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

PPP1R21 TEX10 ZZEF1 FANCA SPHKAP TET1 CAMTA1 NFAT5

8.78e-053641148EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseaseuveal melanoma (is_implicated_in)

BAP1 BRCA2

8.83e-0541142DOID:6039 (is_implicated_in)
Disease3-hydroxyhexanoate measurement

ACSM2A ACSM2B

1.47e-0451142EFO_0800378
Diseaseindoleacetoylcarnitine measurement

ACSM2A ACSM2B

2.20e-0461142EFO_0800106
Diseasemean fractional anisotropy measurement

ZZEF1 DOCK5 PLEC CAMTA1

5.13e-04951144EFO_0008399
Diseasebody fat percentage

PPP1R21 TEX10 ZZEF1 FANCA SPHKAP TET1 CAMTA1 NFAT5

6.30e-044881148EFO_0007800
Disease2-ketocaprylate measurement

HEATR4 ALMS1

6.52e-04101142EFO_0800110
Diseaserenal Wilms' tumor (is_implicated_in)

TEK SUZ12

6.52e-04101142DOID:5176 (is_implicated_in)
DiseaseFanconi anemia (is_implicated_in)

FANCA BRCA2

6.52e-04101142DOID:13636 (is_implicated_in)
DiseaseMalignant neoplasm of breast

KTN1 UBR4 C4orf50 HMOX1 RB1CC1 TEK CLIP1 EIF6 BAP1 BRCA2 MROH7 NIPBL

9.29e-04107411412C0006142
Diseaseuterine fibroid

MYNN DOCK5 SLC7A3 THRB SPINDOC

1.07e-031991145EFO_0000731
DiseasePolydactyly

CEP120 ALMS1 CPLANE1 ARMC8

1.12e-031171144C0152427
Diseasesexual dimorphism measurement

ANKRD31 MRGPRD ADAMTS3 ZZEF1 CLIP1 EIF6 DSN1 CEP120 ABCE1 PRKG2 PLEC ANKS1A

1.19e-03110611412EFO_0021796
Diseaseplasminogen activator inhibitor 1 measurement

RPS6KA2 UBR4 RFX7

1.21e-03541143EFO_0004792
Diseaseskin melanoma (is_implicated_in)

FANCA BRCA2

1.31e-03141142DOID:8923 (is_implicated_in)
DiseaseFanconi anemia

FANCA BRCA2

1.31e-03141142cv:C0015625
Diseasesmoking cessation

ZSWIM8 HMOX1 ALMS1 CAMTA1 NFAT5 ANKS1A

1.68e-033251146EFO_0004319
Diseasefocal segmental glomerulosclerosis

CCDC7 ALMS1

1.71e-03161142EFO_0004236
Diseaseglucose homeostasis measurement, acute insulin response measurement

ZDHHC2 SNX24

2.17e-03181142EFO_0006831, EFO_0006896
DiseaseBone marrow hypocellularity

FANCA BRCA2

2.17e-03181142C1855710
DiseaseMalignant neoplasm of urinary bladder

BAP1 FANCA BRCA2 CHD6

2.22e-031411144C0005684
Diseaseovulation

SYCP2L FANCA

2.42e-03191142GO_0030728
DiseaseAdenocarcinoma of prostate

FANCA BRCA2

2.69e-03201142C0007112
Diseasefreckles

EIF6 FANCA

2.69e-03201142EFO_0003963
Diseaseneuroimaging measurement

ADAMTS3 SNX24 KTN1 SPTBN1 CAPN2 ZNF521 WARS2 PLEC CAMTA1 MAPK6 ANKS1A

2.89e-03106911411EFO_0004346
DiseaseJoubert syndrome 1

CEP120 CPLANE1

2.96e-03211142C4551568
DiseaseBREAST CANCER

RB1CC1 BRCA2

2.96e-03211142114480
Diseasepsychotic symptoms

ARID4B WDFY4 ST18

2.98e-03741143EFO_0005940
DiseasePR interval

SPTBN1 CCDC7 THRB CHD6 PLEC CTNND2 CAMTA1

3.16e-034951147EFO_0004462
Diseaselean body mass

KTN1 TEX10 GHR CEP120 PRKG2 PLEC

3.60e-033791146EFO_0004995

Protein segments in the cluster

PeptideGeneStartEntry
LSQEKLQEQHLSSPQ

BCL2L13

26

Q9BXK5
LESIPTHSDQEKEVN

ARID4B

476

Q4LE39
KEFQQPSQITESTIH

CEP170

246

Q5SW79
EQETTTKLAPEEHVN

ERICH6B

296

Q5W0A0
EQLVQQILDSHQTKP

CAMTA1

241

Q9Y6Y1
SDHLSLPESIKENTL

CAPS2

376

Q9BXY5
NPSELRNLVNKHSET

COPS3

271

Q9UNS2
LDADTINHPAQLSKT

CACNB1

321

Q02641
ISAQLKSHQETDVEP

CCDC7

1221

Q96M83
KSHQETDVEPLTNAI

CCDC7

1226

Q96M83
HLQLPESECSDKQTI

CRYBG3

466

Q68DQ2
LSHDPEQLTKELQQH

ACSM2A

516

Q08AH3
NVTVTLKHINPSQDE

ADGRG2

551

Q8IZP9
QQTLSDSHLPEEALK

ALMS1

1676

Q8TCU4
TQPELIQTHKSQESQ

BAP1

266

Q92560
IQTHKSQESQLPEES

BAP1

271

Q92560
HPLDSLEQKETQEQT

CRACR2A

31

Q9BSW2
PSQKSQQIAALIEDH

ANKS1A

291

Q92625
QNSQELLEPKTHLSE

C2orf73

226

Q8N5S3
IDSEIHQRSKLSPQT

CC2D2B

71

Q6DHV5
HQRSKLSPQTEVSLD

CC2D2B

76

Q6DHV5
SPLQDDRKIQLHSSQ

CTNND2

696

Q9UQB3
EIQVLEHLNTTDPNS

CLK1

206

P49759
QQDDAKDNSIHTVPL

MROH7

356

Q68CQ1
NHLTESIKLSPDQSR

RAB7B

181

Q96AH8
LQELPSVSQETLKHS

IWS1

641

Q96ST2
KTITLHITDVNDNAP

PCDHGB7

436

Q9Y5F8
KDSQELTSLENLEHP

ANKRD31

1456

Q8N7Z5
HLENQIAKSPAIDST

RB1CC1

1266

Q8TDY2
NTKSNHPEEELENIV

C2CD6

371

Q53TS8
QLSSQHEPTDVVDKL

MAPK6

536

Q16659
GKHTEQLLESEPQTV

PARG

161

Q86W56
PENISTQKSLESLNH

FAM205A

921

Q6ZU69
HLPLTKASQTQQEDS

GHDC

96

Q8N2G8
KSQHQEDPNNTSLLT

NIPBL

2121

Q6KC79
ETQPLVNTTDKVHEL

MRGPRD

86

Q8TDS7
HTLSEQDSIQKSPLS

MYNN

536

Q9NPC7
LTHENQTKPSISQIS

KCT2

71

Q8NC54
QEALPLHQETKQESG

KTN1

191

Q86UP2
EPQKEINSLNLTESH

ITGA6

921

P23229
SQQNHSEIKISNPTE

NUSAP1

101

Q9BXS6
SQKAAIEHELPTATQ

PPP1R21

446

Q6ZMI0
VSISVLDKSHDQLNP

DDX31

441

Q9H8H2
QQHSIIDNSLSLKTP

NPIPA2

271

E9PIF3
SSSHLPSENEKQQQI

NFAT5

651

O94916
STEGHDQPQLIKTLQ

PRKG2

336

Q13237
TTDQELQHIRNSLPD

EIF6

76

P56537
QEDKLLHVSSLDTPQ

BTBD18

606

B2RXH4
EQIKPINDTHSLNDT

SLC37A2

56

Q8TED4
SIVNLPSNLEKETTH

ABCE1

71

P61221
VDILHKLSQSPDSNL

ARMC8

646

Q8IUR7
DEASPHILAIKNQAT

ADAMTS3

746

O15072
ICSNSQVHKSPLELE

C4orf50

261

Q6ZRC1
QETDHKSIEDQLQPN

HEATR5B

731

Q9P2D3
HSPLVLIDSQNNTKD

BLNK

431

Q8WV28
SLRNSPKNEVLHTDI

BICRAL

976

Q6AI39
TAVLHEEASKQQPLQ

CCDC107

91

Q8WV48
KPDHEASSQLLSNIL

DOCK5

896

Q9H7D0
HNLTPSQKAEITELS

BRCA2

1101

P51587
EPSNDNVIKQQSDHL

CPLANE1

2611

Q9H799
KVESHIQPSLNQEDI

GHR

551

P10912
QLEQPSTLEESHKNL

CCDC18

1381

Q5T9S5
LHLTEPTTNISREKN

CHD6

1891

Q8TD26
QSLIELKTQNEHEPE

CEP120

346

Q8N960
NTELIHQSSPLLKSE

DIS3L

981

Q8TF46
TEPHSQALQDVEKAI

FANCA

541

O15360
ERLQSKSLHLSPQEQ

DSN1

71

Q9H410
DIHEKTSLSQPQTQS

HEATR4

316

Q86WZ0
TNTPKEEHLLQVADN

DRC7

86

Q8IY82
SSEQREPTNLLHKQL

ECM2

181

O94769
LSKHSQDTQPLEAAL

DAGLA

846

Q9Y4D2
SEDQHLKLSSPENTI

FSIP1

551

Q8NA03
ELQELLTHDTKDQSP

HMOX1

216

P09601
VPEELSGQTNIHLSK

CAPN2

436

P17655
QTISTLHDDEILPSN

MAU2

261

Q9Y6X3
SSQSLPVDNHEKRVI

CFAP47

1611

Q6ZTR5
IQHSLEEIKSNQPSR

SLC7A3

586

Q8WY07
ISEDPENTQTKLEHA

CLIP1

461

P30622
EKIHQSTNQTPALNL

FOCAD

36

Q5VW36
SQLHSKLENDQVIIP

KIF13A

1781

Q9H1H9
PEKSILFQQSQVSEH

WARS2

106

Q9UGM6
SDKVIHVEENPTSQN

RNF133

346

Q8WVZ7
STEHLQQKLVNVSPD

SPHKAP

96

Q2M3C7
ILVNREENSHSKPET

PRUNE2

2551

Q8WUY3
NKTIPLTDNTVIEEH

RPL7L1

171

Q6DKI1
SQKQITIPSQEQEHS

SEMG1

326

P04279
PLEEHVQSTNESLQL

RNF128

376

Q8TEB7
TINHIIPNGKSEDSI

SLC5A3

581

P53794
HTLDLSPSEKSNILE

SPINDOC

116

Q9BUA3
EISLKLHIAQPENNT

PGAP1

546

Q75T13
QSQRTHIKTEQLSPS

SOX9

391

P48436
PQHESLEQTTNNEIK

SPAG17

731

Q6Q759
REATDILSNKPQSLH

ST18

586

O60284
PNTLTEAEKLLTQHE

SPTBN1

1091

Q01082
SEVNELNQIPSHKAL

TET1

2096

Q8NFU7
SNIIIHPSENSDILK

CCDC110

181

Q8TBZ0
LSHDPEQLTKELQQH

ACSM2B

516

Q68CK6
SNEVHNLNPVSAKSL

RNF17

891

Q9BXT8
NIEILNDSHTPGTKV

USP16

591

Q9Y5T5
ESEESSKLSHQPVLL

SNX24

121

Q9Y343
GQELVTKPEHLQESN

STBD1

66

O95210
AQKTELQDPHSLSEL

SYCP2L

601

Q5T4T6
PLATRNSESLHQENK

SUZ12

376

Q15022
QVTEHLPEKIESSLQ

TIMMDC1

241

Q9NPL8
HRELVPDSNSTQLKT

ZNF521

1161

Q96K83
RSTLKNEQSSPHLIQ

THRB

46

P10828
QEETTLCEKHNQPLS

TRIM75

91

A6NK02
PENTENSEKISLQLH

TPP2

556

P29144
EDLPSLSDVQHNIQK

WDFY4

2106

Q6ZS81
LQEQKENPHATSNSI

TEX10

251

Q9NXF1
QAHSSDQLPLQSELK

RFX7

751

Q2KHR2
QPENIKISNITHSSA

TEK

641

Q02763
LNKDTHDQLSEPSEV

PLEC

3966

Q15149
LENQKNSSVPLAEHL

UACA

1156

Q9BZF9
LLDRESQTHKPQTLS

ZSWIM8

1011

A7E2V4
TADETSHLQPLNKRQ

ZZEF1

1446

O43149
EENLSASITKQPIHQ

TAPT1

496

Q6NXT6
PTEEVKTENNNHINL

SUMO4

6

Q6EEV6
KPLRESQSHLLTDSQ

ZDHHC2

326

Q9UIJ5
DHPINEATISIENSK

TEX15

1961

Q9BXT5
LQSLRPHDEDIKTTN

ZNF396

181

Q96N95
GTDSIPNLHKLEQVS

UBR4

4741

Q5T4S7
EVEFSKDHPQTLSIQ

VPS13D

1651

Q5THJ4
SSLIQEPSQQDLHKV

RPS6KA2

381

Q15349