Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN1A SCN3A SCN4A SCN8A	6.09e-06	26	93	4	GO:0005248
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN3A SCN8A	3.43e-05	14	93	3	GO:0031402
GeneOntologyMolecularFunction	sodium channel activity	SCN1A SCN3A SCN4A SCN8A	1.01e-04	52	93	4	GO:0005272
GeneOntologyMolecularFunction	alkali metal ion binding	SCN1A SCN3A SCN8A	2.35e-04	26	93	3	GO:0031420
GeneOntologyBiologicalProcess	membrane depolarization during action potential	SCN1A SCN3A SCN4A SCN8A	1.96e-05	36	92	4	GO:0086010
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN1A SCN3A SCN4A SCN8A	8.00e-07	17	92	4	GO:0001518
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN3A SCN4A SCN8A	7.67e-06	29	92	4	GO:0034706
Domain	Na_channel_asu	SCN1A SCN3A SCN4A SCN8A	1.04e-07	10	90	4	IPR001696
Domain	Na_trans_assoc	SCN1A SCN3A SCN4A SCN8A	1.04e-07	10	90	4	IPR010526
Domain	Na_trans_assoc	SCN1A SCN3A SCN4A SCN8A	1.04e-07	10	90	4	PF06512
Domain	IQ	MYO7A MYO10 SCN1A SCN3A SCN4A SCN8A	1.18e-06	71	90	6	PF00612
Domain	Na_trans_cytopl	SCN1A SCN3A SCN8A	2.14e-06	6	90	3	PF11933
Domain	Na_trans_cytopl	SCN1A SCN3A SCN8A	2.14e-06	6	90	3	IPR024583
Domain	IQ	MYO7A MYO10 SCN1A SCN3A SCN4A SCN8A	2.57e-06	81	90	6	SM00015
Domain	IQ_motif_EF-hand-BS	MYO7A MYO10 SCN1A SCN3A SCN4A SCN8A	4.76e-06	90	90	6	IPR000048
Domain	IQ	MYO7A MYO10 SCN1A SCN3A SCN4A SCN8A	5.76e-06	93	90	6	PS50096
Domain	Channel_four-helix_dom	SCN1A SCN3A SCN4A SCN8A	1.64e-04	57	90	4	IPR027359
Domain	-	SCN1A SCN3A SCN4A SCN8A	1.64e-04	57	90	4	1.20.120.350
Domain	Ion_trans_dom	SCN1A SCN3A SCN4A SCN8A TRPM1	2.26e-04	114	90	5	IPR005821
Domain	Ion_trans	SCN1A SCN3A SCN4A SCN8A TRPM1	2.26e-04	114	90	5	PF00520
Domain	-	CUX2 POU5F2 CUX1	2.91e-04	27	90	3	1.10.260.40
Domain	Lambda_DNA-bd_dom	CUX2 POU5F2 CUX1	3.61e-04	29	90	3	IPR010982
Domain	CUT	CUX2 CUX1	4.75e-04	7	90	2	PS51042
Domain	CUT	CUX2 CUX1	4.75e-04	7	90	2	PF02376
Domain	CUT_dom	CUX2 CUX1	4.75e-04	7	90	2	IPR003350
Domain	CUT	CUX2 CUX1	4.75e-04	7	90	2	SM01109
Domain	MARCH-like	MARCHF8 MARCHF1	6.31e-04	8	90	2	IPR033275
Domain	MYTH4	MYO7A MYO10	8.09e-04	9	90	2	PS51016
Domain	MyTH4_dom	MYO7A MYO10	8.09e-04	9	90	2	IPR000857
Domain	MyTH4	MYO7A MYO10	8.09e-04	9	90	2	PF00784
Domain	MyTH4	MYO7A MYO10	8.09e-04	9	90	2	SM00139
Domain	RINGv	MARCHF8 MARCHF1	1.23e-03	11	90	2	PF12906
Domain	ZF_RING_CH	MARCHF8 MARCHF1	1.23e-03	11	90	2	PS51292
Domain	FERM_M	MYO7A MYO10 KRIT1	1.41e-03	46	90	3	PF00373
Domain	-	MYO7A MYO10 KRIT1	1.70e-03	49	90	3	1.20.80.10
Domain	FERM_central	MYO7A MYO10 KRIT1	1.70e-03	49	90	3	IPR019748
Domain	FERM_domain	MYO7A MYO10 KRIT1	1.70e-03	49	90	3	IPR000299
Domain	FERM_1	MYO7A MYO10 KRIT1	1.80e-03	50	90	3	PS00660
Domain	FERM_2	MYO7A MYO10 KRIT1	1.80e-03	50	90	3	PS00661
Domain	FERM_3	MYO7A MYO10 KRIT1	1.80e-03	50	90	3	PS50057
Domain	Band_41_domain	MYO7A MYO10 KRIT1	1.80e-03	50	90	3	IPR019749
Domain	B41	MYO7A MYO10 KRIT1	1.80e-03	50	90	3	SM00295
Domain	FERM/acyl-CoA-bd_prot_3-hlx	MYO7A MYO10 KRIT1	1.80e-03	50	90	3	IPR014352
Domain	WH2	INF2 PXK	2.64e-03	16	90	2	PF02205
Domain	EF-hand-dom_pair	SCN1A RASGRP3 SCN3A EHD1 SCN8A CCAR1	2.64e-03	287	90	6	IPR011992
Domain	Znf_RING-CH	MARCHF8 MARCHF1	2.98e-03	17	90	2	IPR011016
Domain	RINGv	MARCHF8 MARCHF1	2.98e-03	17	90	2	SM00744
Domain	RasGEF_N	RASGRP3 RASGEF1C	4.54e-03	21	90	2	PF00618
Domain	WH2_dom	INF2 PXK	4.54e-03	21	90	2	IPR003124
Domain	Ras-like_Gua-exchang_fac_N	RASGRP3 RASGEF1C	4.98e-03	22	90	2	IPR000651
Domain	RASGEF_NTER	RASGRP3 RASGEF1C	4.98e-03	22	90	2	PS50212
Domain	TIR	TIRAP TLR2	4.98e-03	22	90	2	PF01582
Domain	Homeodomain-like	CUX2 IRX5 POU5F2 TSHZ1 TERF1 CUX1	5.38e-03	332	90	6	IPR009057
Domain	-	TIRAP TLR2	5.44e-03	23	90	2	3.40.50.10140
Domain	F-box_dom	FBXW10B FBXW10 FBXL6	5.69e-03	75	90	3	IPR001810
Domain	HOX	CUX2 IRX5 POU5F2 TSHZ1 CUX1	5.78e-03	237	90	5	SM00389
Domain	WH2	INF2 PXK	5.92e-03	24	90	2	PS51082
Domain	TIR	TIRAP TLR2	5.92e-03	24	90	2	PS50104
Domain	HOMEOBOX_2	CUX2 IRX5 POU5F2 TSHZ1 CUX1	5.99e-03	239	90	5	PS50071
Domain	Homeobox_dom	CUX2 IRX5 POU5F2 TSHZ1 CUX1	5.99e-03	239	90	5	IPR001356
Domain	SH3_9	FNBP1 NEB SH3BP4	6.34e-03	78	90	3	PF14604
Domain	HR1_rho-bd	FNBP1 RHPN2	6.41e-03	25	90	2	IPR011072
Domain	TIR_dom	TIRAP TLR2	6.41e-03	25	90	2	IPR000157
Domain	G-protein_beta_WD-40_rep	FBXW10B FBXW10 WDSUB1	8.04e-03	85	90	3	IPR020472
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SCN1A SCN3A SCN4A SCN8A	1.25e-05	31	66	4	M877
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	SCN1A SCN3A SCN4A SCN8A	1.43e-05	32	66	4	M27455
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN1A SCN3A SCN4A SCN8A	6.24e-09	9	94	4	16382098
Pubmed	Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.	SCN1A SCN3A SCN4A SCN8A	6.24e-09	9	94	4	15746173
Pubmed	IRX3/5 regulate mitotic chromatid segregation and limb bud shape.	CUX2 IRX5 ESR1 CUX1	1.04e-08	10	94	4	32907847
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN3A SCN8A	7.63e-08	4	94	3	17537961
Pubmed	Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.	SCN1A SCN3A SCN8A	7.63e-08	4	94	3	35031483
Pubmed	Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.	SCN1A SCN3A SCN8A	7.63e-08	4	94	3	29578003
Pubmed	Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.	SCN1A SCN3A NEB	1.90e-07	5	94	3	1679748
Pubmed	A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.	SCN1A SCN3A NEB	1.90e-07	5	94	3	8812438
Pubmed	Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.	SCN3A SCN4A SCN8A	1.90e-07	5	94	3	17724025
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN1A SCN3A SCN8A	3.80e-07	6	94	3	23652591
Pubmed	Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.	SCN1A SCN3A SCN8A	4.13e-06	12	94	3	30175250
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	SCN1A SCN3A SCN8A	5.36e-06	13	94	3	15123669
Pubmed	Cux1 and Cux2 selectively target basal and apical dendritic compartments of layer II-III cortical neurons.	CUX2 CUX1	7.23e-06	2	94	2	25059644
Pubmed	Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.	SCN1A SCN8A	7.23e-06	2	94	2	37901435
Pubmed	An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.	SCN1A SCN8A	7.23e-06	2	94	2	26410685
Pubmed	The neurosteroid pregnenolone promotes degradation of key proteins in the innate immune signaling to suppress inflammation.	TIRAP TLR2	7.23e-06	2	94	2	30647133
Pubmed	CUX2 deficiency causes facilitation of excitatory synaptic transmission onto hippocampus and increased seizure susceptibility to kainate.	CUX2 CUX1	7.23e-06	2	94	2	35581205
Pubmed	CCAAT-displacement protein/cut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-α) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE).	ESR1 CUX1	7.23e-06	2	94	2	30964885
Pubmed	Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.	SCN1A SCN3A	7.23e-06	2	94	2	24990319
Pubmed	Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.	SCN1A SCN8A	7.23e-06	2	94	2	31943325
Pubmed	Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.	SCN1A SCN3A	7.23e-06	2	94	2	27690330
Pubmed	MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation.	MARCHF8 MARCHF1	7.23e-06	2	94	2	21757542
Pubmed	Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.	SCN1A SCN3A	7.23e-06	2	94	2	23965409
Pubmed	The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis.	TIRAP TLR2	7.23e-06	2	94	2	18369480
Pubmed	Cux-1 and Cux-2 control the development of Reelin expressing cortical interneurons.	CUX2 CUX1	7.23e-06	2	94	2	18327765
Pubmed	A unique variant of a homeobox gene related to Drosophila cut is expressed in mouse testis.	CUX2 CUX1	7.23e-06	2	94	2	8879483
Pubmed	Toll-like receptor 2 modulates left ventricular function following ischemia-reperfusion injury.	TIRAP TLR2	7.23e-06	2	94	2	16980352
Pubmed	FBXW10 promotes hepatocarcinogenesis in male patients and mice.	FBXW10B FBXW10	7.23e-06	2	94	2	31400758
Pubmed	Differential role of Toll-interleukin 1 receptor domain-containing adaptor protein in Toll-like receptor 2-mediated regulation of gene expression of hepatic cytokines and drug-metabolizing enzymes.	TIRAP TLR2	7.23e-06	2	94	2	21303924
Pubmed	Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.	SCN1A SCN8A	7.23e-06	2	94	2	33411788
Pubmed	Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.	FBXW10B FBXW10	7.23e-06	2	94	2	37450367
Pubmed	Expression of a cut-related homeobox gene in developing and polycystic mouse kidney.	CUX2 CUX1	7.23e-06	2	94	2	8840273
Pubmed	Cux1 Enables Interhemispheric Connections of Layer II/III Neurons by Regulating Kv1-Dependent Firing.	CUX2 CUX1	7.23e-06	2	94	2	26804994
Pubmed	Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.	SCN1A SCN8A	7.23e-06	2	94	2	37665666
Pubmed	The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.	SCN1A SCN8A	7.23e-06	2	94	2	17881658
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	CDC37 RALGAPA1 MYO10 MACROD2 RASGEF1C TERF1	1.65e-05	197	94	6	20811636
Pubmed	Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection.	MARCHF8 MARCHF1	2.16e-05	3	94	2	27503069
Pubmed	Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.	TIRAP TLR2	2.16e-05	3	94	2	12447441
Pubmed	SCN1A, ABCC2 and UGT2B7 gene polymorphisms in association with individualized oxcarbazepine therapy.	SCN1A ABCC2	2.16e-05	3	94	2	25823783
Pubmed	Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).	SCN1A SCN3A	2.16e-05	3	94	2	33895391
Pubmed	Membrane-associated RING-CH (MARCH) 8 mediates the ubiquitination and lysosomal degradation of the transferrin receptor.	MARCHF8 MARCHF1	2.16e-05	3	94	2	23606747
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN1A SCN3A	2.16e-05	3	94	2	23859570
Pubmed	A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis.	TIRAP TLR2	2.16e-05	3	94	2	17322885
Pubmed	MyD88 Adapter-like (Mal)/TIRAP Is Required for Cytokine Production by Splenic Ly6CloTLR2hi but Not by Ly6ChiTLR2hi Monocytes during Trypanosoma cruzi Infection.	TIRAP TLR2	2.16e-05	3	94	2	27646001
Pubmed	Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity.	TIRAP TLR2	2.16e-05	3	94	2	28235196
Pubmed	Human MARCH1, 2, and 8 block Ebola virus envelope glycoprotein cleavage via targeting furin P domain.	MARCHF8 MARCHF1	2.16e-05	3	94	2	38299743
Pubmed	GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.	SCN1A SCN3A	2.16e-05	3	94	2	27816501
Pubmed	Ubiquitination by the membrane-associated RING-CH-8 (MARCH-8) ligase controls steady-state cell surface expression of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) receptor 1.	MARCHF8 MARCHF1	2.16e-05	3	94	2	23300075
Pubmed	Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.	SCN1A SCN8A	2.16e-05	3	94	2	26182346
Pubmed	MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3.	TIRAP TLR2	2.16e-05	3	94	2	19717524
Pubmed	De novo SCN1A, SCN8A, and CLCN2 mutations in childhood absence epilepsy.	SCN1A SCN8A	2.16e-05	3	94	2	31054517
Pubmed	Sodium channels SCN1A, SCN2A and SCN3A in familial autism.	SCN1A SCN3A	2.16e-05	3	94	2	12610651
Pubmed	Epigenetic Modifications in the Biology of Nonalcoholic Fatty Liver Disease: The Role of DNA Hydroxymethylation and TET Proteins.	TET1 HMCES	2.16e-05	3	94	2	26356709
Pubmed	CD36 is a sensor of diacylglycerides.	TIRAP TLR2	2.16e-05	3	94	2	15690042
Pubmed	Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.	SCN1A SCN3A	2.16e-05	3	94	2	18784617
Pubmed	Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.	SCN1A SCN3A	2.16e-05	3	94	2	17544618
Pubmed	mTORC1 Signaling Controls TLR2-Mediated T-Cell Activation by Inducing TIRAP Expression.	TIRAP TLR2	2.16e-05	3	94	2	32698010
Pubmed	Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.	SCN1A SCN8A	2.16e-05	3	94	2	32845893
Pubmed	CCAR1, a key regulator of mediator complex recruitment to nuclear receptor transcription complexes.	ESR1 CCAR1	2.16e-05	3	94	2	18722177
Pubmed	Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.	SCN1A SCN8A	2.16e-05	3	94	2	28518218
Pubmed	Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.	SCN1A SCN8A	2.16e-05	3	94	2	24704313
Pubmed	Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.	SCN1A ABCC2	2.16e-05	3	94	2	25155934
Pubmed	The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels.	SCN1A SCN8A	2.16e-05	3	94	2	28117367
Pubmed	Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.	SCN1A SCN8A	2.16e-05	3	94	2	17928448
Pubmed	RUNX1-PDIA5 Axis Promotes Malignant Progression of Glioblastoma by Regulating CCAR1 Protein Expression.	CCAR1 PDIA5	2.16e-05	3	94	2	39247813
Pubmed	Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.	SCN1A SCN3A	2.16e-05	3	94	2	14973256
Pubmed	Requirement of TLR2-mediated signaling for the induction of IL-15 gene expression in human monocytic cells by HSV-1.	TIRAP TLR2	2.16e-05	3	94	2	18583567
Pubmed	Genome-wide association analyses identify variants in developmental genes associated with hypospadias.	IRX5 DGKK EXOC3	4.21e-05	25	94	3	25108383
Pubmed	Thymic CD4 T cell selection requires attenuation of March8-mediated MHCII turnover in cortical epithelial cells through CD83.	MARCHF8 MARCHF1	4.32e-05	4	94	2	27503071
Pubmed	A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.	TIRAP TLR2	4.32e-05	4	94	2	19509286
Pubmed	Racial variation in toll-like receptor variants among women with pelvic inflammatory disease.	TIRAP TLR2	4.32e-05	4	94	2	23255565
Pubmed	Innate immunity mediates myocardial preconditioning through Toll-like receptor 2 and TIRAP-dependent signaling pathways.	TIRAP TLR2	4.32e-05	4	94	2	20061547
Pubmed	Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.	TIRAP TLR2	4.32e-05	4	94	2	19889726
Pubmed	Induction of distinct TLR2-mediated proinflammatory and proadhesive signaling pathways in response to Porphyromonas gingivalis fimbriae.	TIRAP TLR2	4.32e-05	4	94	2	19454663
Pubmed	Models for discovery of targeted therapy in genetic epileptic encephalopathies.	SCN1A SCN8A	4.32e-05	4	94	2	28742937
Pubmed	Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4.	TIRAP TLR2	4.32e-05	4	94	2	15247281
Pubmed	Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.	SCN1A SCN3A	4.32e-05	4	94	2	35801810
Pubmed	MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction.	TIRAP TLR2	4.32e-05	4	94	2	16439361
Pubmed	MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.	TIRAP TLR2	4.32e-05	4	94	2	19592497
Pubmed	Biochemical characterization of the mammalian Cux2 protein.	CUX2 CUX1	4.32e-05	4	94	2	15656993
Pubmed	The HLA-DRalpha chain is modified by polyubiquitination.	MARCHF8 MARCHF1	4.32e-05	4	94	2	19117940
Pubmed	Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion.	MYO10 TLR2	4.32e-05	4	94	2	28289096
Pubmed	Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.	SCN1A SCN8A	4.32e-05	4	94	2	21156207
Pubmed	Vertebrate unconventional myosins.	MYO7A MYO10	4.32e-05	4	94	2	8690736
Pubmed	Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis.	TIRAP TLR2	4.32e-05	4	94	2	16832055
Pubmed	Cux1 and Cux2 regulate dendritic branching, spine morphology, and synapses of the upper layer neurons of the cortex.	CUX2 CUX1	4.32e-05	4	94	2	20510857
Pubmed	Toll-like receptor signal transduction and the tailoring of innate immunity: a role for Mal?	TIRAP TLR2	4.32e-05	4	94	2	12072368
Pubmed	Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.	SCN1A SCN3A	4.32e-05	4	94	2	8974318
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SIRT2 MYO7A INF2 MYO10 SPEG TTLL4 MTMR8 SCN8A OSBPL5 PDIA5 WNK2 SH3BP4	4.33e-05	1105	94	12	35748872
Pubmed	FBXW10-S6K1 promotes ANXA2 polyubiquitination and KRAS activation to drive hepatocellular carcinoma development in males.	FBXW10B FBXW10	7.19e-05	5	94	2	37277019
Pubmed	Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21.	TLR2 PDCD4	7.19e-05	5	94	2	22087031
Pubmed	Evaluation of Toll-like receptor and adaptor molecule polymorphisms for susceptibility to tuberculosis in a Colombian population.	TIRAP TLR2	7.19e-05	5	94	2	22221660
Pubmed	Induction of macrophage-derived SLPI by Mycobacterium tuberculosis depends on TLR2 but not MyD88.	TIRAP TLR2	7.19e-05	5	94	2	16236128
Pubmed	Early development of electrical excitability in the mouse enteric nervous system.	SCN3A SCN8A	7.19e-05	5	94	2	22875929
Pubmed	Toll-like receptor 4 signalling through MyD88 is essential to control Salmonella enterica serovar typhimurium infection, but not for the initiation of bacterial clearance.	TIRAP TLR2	7.19e-05	5	94	2	19930040
Pubmed	NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.	TIRAP TLR2	7.19e-05	5	94	2	17360653
Pubmed	Primary structure, neural-specific expression, and chromosomal localization of Cux-2, a second murine homeobox gene related to Drosophila cut.	CUX2 CUX1	7.19e-05	5	94	2	8798433
Pubmed	Mal mediates TLR-induced activation of CREB and expression of IL-10.	TIRAP TLR2	7.19e-05	5	94	2	21398611
Pubmed	Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.	SCN1A SCN3A	7.19e-05	5	94	2	24337656
Pubmed	Genetic variation of innate immune genes in HIV-infected african patients with or without oropharyngeal candidiasis.	TIRAP TLR2	7.19e-05	5	94	2	20577092
Cytoband	Ensembl 112 genes in cytogenetic band chr2q24	PLA2R1 SCN1A SCN3A WDSUB1	1.40e-04	127	94	4	chr2q24
Cytoband	10q24	ABCC2 PDCD4	2.36e-03	35	94	2	10q24
Cytoband	3q21.3	CFAP92 HMCES	3.88e-03	45	94	2	3q21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr3q21	CFAP92 PDIA5 HMCES	4.42e-03	160	94	3	chr3q21
Cytoband	17p12	FBXW10B FBXW10	4.58e-03	49	94	2	17p12
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN3A SCN4A SCN8A	1.66e-08	9	63	4	1203
GeneFamily	CUT class homeoboxes and pseudogenes	CUX2 CUX1	4.23e-04	9	63	2	527
GeneFamily	WD repeat domain containing\|F-box and WD repeat domain containing	FBXW10B FBXW10	6.44e-04	11	63	2	559
GeneFamily	Ring finger proteins\|Membrane associated ring-CH-type fingers	MARCHF8 MARCHF1	6.44e-04	11	63	2	60
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	MYO7A MYO10 KRIT1	7.03e-04	50	63	3	1293
Coexpression	MTOR_UP.N4.V1_DN	XYLT1 MARCHF8 SCN3A FAM13B S1PR1 PDCD4 CUX1	3.97e-06	184	92	7	M2756
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIRAP ESR1 RASGRP3 TTLL4 ZNF770 RRAGB CCDC191	9.60e-08	180	92	7	be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIRAP ESR1 RASGRP3 TTLL4 ZNF770 RRAGB CCDC191	9.60e-08	180	92	7	3b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	CUX2 RHPN2 SCN8A MACROD2 ABCC2 WNK2 SH3BP4	1.54e-07	193	92	7	503a979328c68b096680b71359a26f02fafdff35
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLA2R1 RHPN2 OXGR1 HID1 PDCD4 WNK2 SH3BP4	1.96e-07	200	92	7	030efc36bbb848da31b0db3f74d46aac9c79cc9b
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO10 RASGRP3 NRK HID1 S1PR1 TRIM37	2.44e-06	186	92	6	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Npw\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CUX2 DGKK RASGEF1C PDIA5 SPAG5	3.78e-06	113	92	5	165de4316059222f33d1e51aeff4554037c0b937
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMC2 SCN1A OXGR1 ABCC2 WNK2	1.27e-05	145	92	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHBDL2 IRX5 TMC2 DGKK WNK2	1.93e-05	158	92	5	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHBDL2 IRX5 TMC2 DGKK WNK2	1.93e-05	158	92	5	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMC2 OXGR1 ABCC2 NEB WNK2	2.17e-05	162	92	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	367C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	POU5F2 EXOC3 HID1 CCDC191 FAM13B	2.30e-05	164	92	5	1aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCell	B_cells-ABCs\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	RASGRP3 SCN3A WFDC8 MARCHF1 DNAH8	2.30e-05	164	92	5	f45013706a917f0f0d69c23f288128f252cd60c7
ToppCell	facs-Heart-RV-24m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INF2 MYO10 OXGR1 S1PR1 TRIM37	2.59e-05	168	92	5	831b000e26b4a7e7fdfa3988372e0281c45eadbb
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLA2R1 ZNF560 PDE1B SCN1A RASGEF1C	2.82e-05	171	92	5	f047a0cc2ce0a062ec502aa9cb91b1202f437f29
ToppCell	10x5'-Liver-Lymphocytic_B-ABC_aged-B_memory\|Liver / Manually curated celltypes from each tissue	ESR1 RASGRP3 MACROD2 NEB DNAH8	2.82e-05	171	92	5	eb47f4a09a630ed14a0898377039ed50ef7cc292
ToppCell	3'_v3-blood-Lymphocytic_B-Naive_B_cells\|blood / Manually curated celltypes from each tissue	SCN3A SCN4A MACROD2 MARCHF1 CCDC191	2.90e-05	172	92	5	f16f90d17feac1ee52fd513907b28456865fd31d
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PDE1B RHPN2 RASGRP3 EHD1 S1PR1	2.98e-05	173	92	5	b0ff9808e38cb64a734ced498cd0546728746cd5
ToppCell	NS-moderate-d_16-33-Lymphoid-B_cell\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RASGRP3 SCN3A MARCHF1 DNAH8 PXK	3.32e-05	177	92	5	320fd77c7c98e9305dcc34a168ec9d674539ed65
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	3.41e-05	178	92	5	5d41fede13c8e64b6fdaf2155f1eb72bcfc32fdb
ToppCell	Control-Lymphocyte-B-B_naive\|Control / Disease, Lineage and Cell Type	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	3.50e-05	179	92	5	35994281904bfe38766e715ab608211a5ca865a9
ToppCell	B_cells-Naive_B_cells_\|World / Immune cells in Kidney/Urine in Lupus Nephritis	RASGRP3 SCN3A SCN4A MACROD2 MARCHF1	3.79e-05	182	92	5	63c3b63315276b66667d49fab09661ac320e7a36
ToppCell	remission-B_naive\|World / disease stage, cell group and cell class	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	3.79e-05	182	92	5	cc1dfd2de35aee1a26f7efd78e108b60a3556ec5
ToppCell	remission-B_naive\|remission / disease stage, cell group and cell class	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	3.89e-05	183	92	5	280d55d67f1d44594206da2f3a332c9d799dbdf0
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-B_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	3.99e-05	184	92	5	12cbb6d5edc3c0a896d080ca990af57dbb6c9960
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP3 MARCHF1 S1PR1 PDCD4 PXK	4.10e-05	185	92	5	eb338fcda0b237c2e0b9b4b0daf51febbfe1d79c
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP3 MARCHF1 S1PR1 PDCD4 PXK	4.10e-05	185	92	5	c31bb53852caf36964b83b28bcaee07b679da779
ToppCell	moderate-Lymphoid-B_cell\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RASGRP3 SCN3A MARCHF1 DNAH8 PXK	4.21e-05	186	92	5	fd2c4c3e8929ca5d64f6c5064e5f3d3d6ba07b5f
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOK6 SCN1A SCN4A CCDC87 RASGEF1C	4.21e-05	186	92	5	bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell	NS-moderate-d_07-13-Lymphoid-B_cell\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RASGRP3 SCN3A MARCHF1 DNAH8 PXK	4.42e-05	188	92	5	e9ed34cfea1d93eaa8e63d5b5dbb64f1520d9c4c
ToppCell	droplet-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRX5 RASGRP3 PDIA5 S1PR1 TRIM37	4.54e-05	189	92	5	88c0dda28f072368c0df30fc82ee3af9c7670f6c
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STK32A RHPN2 RASGRP3 PDIA5 HID1	4.54e-05	189	92	5	9da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCell	droplet-Kidney-nan-18m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRX5 RASGRP3 PDIA5 S1PR1 TRIM37	4.54e-05	189	92	5	91261fe86f0d54b9697f85bb4d3ebdc8975b1bfa
ToppCell	facs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO10 RASGRP3 DNAH8 S1PR1 TRIM37	4.54e-05	189	92	5	16e019fd6e2376110b767739754389891f391669
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	4.65e-05	190	92	5	112706d64ee73b55dcf76f33ca064ab1fc6ce87f
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-Naive_B_cells\|bone_marrow / Manually curated celltypes from each tissue	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	4.65e-05	190	92	5	3d45d5011305f13634013d9eeb98f235517dd54e
ToppCell	severe-B_naive\|severe / disease stage, cell group and cell class	SCN3A MACROD2 MARCHF1 CCDC191 PDCD4	4.65e-05	190	92	5	2430a1fd18385305bf1b604747ff64026a8d5edf
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_activate-7\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP3 SCN3A MACROD2 MARCHF1 TRIM22	4.77e-05	191	92	5	2feab42ac6d29fa4eac78f3f78a5f8aa0a559523
ToppCell	Control-Lymphoid_B\|Control / Disease group, lineage and cell class	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	4.77e-05	191	92	5	0a760cd3a48c487ec899adb882fddea8914cfe0c
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STK32A RHPN2 RASGRP3 PDIA5 HID1	4.77e-05	191	92	5	3307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCell	3'_v3-bone_marrow-Lymphocytic_B\|bone_marrow / Manually curated celltypes from each tissue	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	4.89e-05	192	92	5	8a284b6e499f5a3c116d5551430f00ecad4a3681
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	4.89e-05	192	92	5	ee309564ac6136c1dc314d5cd3603687ee2266f2
ToppCell	moderate-Lymphoid-B_cell\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RASGRP3 SCN3A MARCHF1 DNAH8 PXK	4.89e-05	192	92	5	ae3727503c3b9f4695e565fd3161cc33b898f349
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-11\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.01e-05	193	92	5	cf4ba50aa4a00d1ba22fc7626d49a4104377d5d9
ToppCell	normal-na-Lymphocytic_B-B_naive\|normal / PBMC cell types (v2) per disease, treatment status, and sex	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.01e-05	193	92	5	98279a3c69f1df062c4a8333e46c8fd649bf86b1
ToppCell	droplet-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP3 EHD1 DNAH8 S1PR1 TRIM37	5.01e-05	193	92	5	7cff1e859b296b1032eebcfc0f99a504f3bda2c9
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-B_naive-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.01e-05	193	92	5	95ec708d963e9411e2dcf65650ae71a26e9d0e7f
ToppCell	normal-na-Lymphocytic_B-B_naive-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.01e-05	193	92	5	dd199163fc13f3d411fe741cf003237064349e22
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.01e-05	193	92	5	6e6c5ae39ea880ba809019a7d39f50e4e02007ed
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.01e-05	193	92	5	c04ac5884be4245b75d211046f04d76ae0cfb998
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-B_naive\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.01e-05	193	92	5	d0d0835304647758e6ad4348402a4f76a76137a0
ToppCell	COVID-19_Convalescent-Lymphoid_B\|COVID-19_Convalescent / Disease group, lineage and cell class	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.01e-05	193	92	5	e0973f3f3ae8ddcb6e22af5eb1e0fe6fe607a20b
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.14e-05	194	92	5	24f9de4781666c96c4a2d04f8a444543dbd99cbe
ToppCell	PBMC-Control-Lymphocyte-B\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.14e-05	194	92	5	a8daf73c186a15adb9ea02793d4bd9cb35c66290
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-B_naive-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.14e-05	194	92	5	a778b5d1f7661c29dc8d894827891c1036255749
ToppCell	COVID-19_Moderate-B_naive\|COVID-19_Moderate / disease group, cell group and cell class	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.14e-05	194	92	5	8c41a37467bfd4966ecd09dde68c543dc01b6ad0
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.14e-05	194	92	5	82753b90ca3b563275c41b6040ebbcd99b185e24
ToppCell	PBMC-Control-Lymphocyte-B\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.14e-05	194	92	5	39121c7d537ac103f6959271d814fd327be7114f
ToppCell	COVID-19_Moderate-B_naive\|World / disease group, cell group and cell class	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.14e-05	194	92	5	1f81d618799e482a36dce528bba70f52cc69a901
ToppCell	PBMC-Control-Lymphocyte-B-B_cell\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.14e-05	194	92	5	60542304899b99caa38e4abf6b71ba986fa6c399
ToppCell	Control-Lymphoid_B-B_naive\|Control / Disease group, lineage and cell class	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.14e-05	194	92	5	4f9600960a287cfc020c06b4af3528d4e5797916
ToppCell	COVID-19_Severe-B_naive\|World / disease group, cell group and cell class	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.14e-05	194	92	5	d363963a6caeedf4f9e9ad22dcf9b66b85c79a48
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.14e-05	194	92	5	287439c51528d7bb13bd235875d85631dc91ed91
ToppCell	PBMC-Control-Lymphocyte-B-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.14e-05	194	92	5	ad9a8cc57f54bdec4cd6990b2cace947b7a163c9
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.26e-05	195	92	5	b74645072a063732d5be43036ce0e9568eff3d14
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.26e-05	195	92	5	8f5a664dd65c38afe23c6acd0a9c22ba4fd347ed
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.26e-05	195	92	5	e830f0c545be87a1056a4505bdf6845e5ac7750d
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.26e-05	195	92	5	4b882a71f0e02fef5580e9d9bc42245cf9df2e57
ToppCell	COVID-19_Severe-Lymphoid_B-B_naive\|COVID-19_Severe / Disease group, lineage and cell class	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.26e-05	195	92	5	71563e838fcda34a9a209c5433e0d84420373402
ToppCell	mild_COVID-19-B_naive\|mild_COVID-19 / disease group, cell group and cell class (v2)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.39e-05	196	92	5	00398079d3ac14dc2026c0cbd7388f1f3257b134
ToppCell	Healthy_donor-B_naive\|Healthy_donor / disease group, cell group and cell class (v2)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.39e-05	196	92	5	cf254b1466357984201595fa32408d659eb741ef
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.39e-05	196	92	5	d7e6c89cb49933b4a86d26d15f6772f2481d37ef
ToppCell	COVID-19_Mild-Lymphoid_B-B_naive\|COVID-19_Mild / Disease group, lineage and cell class	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.39e-05	196	92	5	4b3ceb1f85be0fa8d53dc5548326ab0a5239a8b9
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.39e-05	196	92	5	fcbfd8c4771d99a45fc53e482ef98edabe8ef591
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ESR1 RASGRP3 TET1 HID1 DNAH8	5.39e-05	196	92	5	fd18a9ae8401121ae276adff1a85d5f938e2df91
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.39e-05	196	92	5	f45cb8f714ae7ac800768df65f299b98a2d42962
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.52e-05	197	92	5	f7a8440d2b8b17d9726c6fe3dd383effbfebab13
ToppCell	COVID-19_Severe-Lymphoid_B\|COVID-19_Severe / Disease group, lineage and cell class	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.52e-05	197	92	5	25303329b051831cf2ed4df68f3948308e5fbd96
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.52e-05	197	92	5	5c67ed18fb92aec73c79f4db6d80cec777d9ba44
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.52e-05	197	92	5	368a7908435cb0d0feea135345e7179584a1e0cf
ToppCell	COVID-19_Mild-Lymphoid_B\|COVID-19_Mild / Disease group, lineage and cell class	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.52e-05	197	92	5	ff25c0e184bd0f068014bc3f5eba3aee17511b87
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	RASGRP3 SCN3A MACROD2 MARCHF1 CCDC191	5.52e-05	197	92	5	7cae4f3eabfebce101de7bb7defb17d6c5360b58
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	XYLT1 STK32A DOK6 SCN1A SCN3A	5.93e-05	200	92	5	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	XYLT1 STK32A DOK6 SCN1A SCN3A	5.93e-05	200	92	5	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	XYLT1 STK32A DOK6 SCN1A SCN3A	5.93e-05	200	92	5	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	XYLT1 STK32A DOK6 SCN1A SCN3A	5.93e-05	200	92	5	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	XYLT1 STK32A DOK6 SCN1A SCN3A	5.93e-05	200	92	5	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	XYLT1 STK32A DOK6 SCN1A SCN3A	5.93e-05	200	92	5	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLA2R1 RHPN2 HID1 WNK2 SH3BP4	5.93e-05	200	92	5	85c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_activate-7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FBXW10B SCN8A ABCC2 CCDC191	1.35e-04	126	92	4	518a6e4919981b556ce6b451a91270dba976bc75
ToppCell	Control-B_activate-7\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TCP10L FBXW10B SCN8A ABCC2	1.53e-04	130	92	4	d3343c19d61928f18e7d707eda5dec6e0fd2a9a2
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Sla\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EVC2 ESR1 SPAG5 SH3BP4	1.62e-04	132	92	4	ddebc0b233fdbb73ceb70187945bbed8fd273f2a
ToppCell	LPS-IL1RA-Myeloid-Monocytes,_Macrophages-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO7A ESR1 SCN8A MARCHF1	1.97e-04	139	92	4	505bf5a483fc2ba69377db9850c3b26ab2f416d1
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Macc1_Lrg1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CUX2 EVC2 RASGEF1C SPAG5	2.14e-04	142	92	4	d08e1880425d285c4433014fe0242ac7ff7734af
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CUX2 SCN3A OXGR1 SH3BP4	2.38e-04	146	92	4	bee5074c29b132180d35f57d307e342efa9b8cd1
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CUX2 EVC2 RASGEF1C SPAG5	2.51e-04	148	92	4	d5cace5605bff2bb8248fadb51f2dad7539930ba
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RHPN2 SCN3A MARCHF1 DNAH8	2.64e-04	150	92	4	53de595376a9fc92491dfd58ff25938b0bf79903
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RHPN2 SCN3A MARCHF1 DNAH8	2.64e-04	150	92	4	e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCell	Cerebellum-Macroglia-ASTROCYTE\|Cerebellum / BrainAtlas - Mouse McCarroll V32	STK32A IRX5 IGSF1 SPAG5	2.71e-04	151	92	4	71841d2001200d1595c85c2b007ee20791a72927
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EVC2 TLR2 EHD1 CUX1	2.71e-04	151	92	4	7b50425d2bbd7b6ff2a6e67d3e2470a4455740e0
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	STK32A IRX5 IGSF1 SPAG5	2.71e-04	151	92	4	60aced0c1cc6b509b73308d03d58a3c44d712ef4
Drug	APETx1, Anthopleura elegantissima	SCN3A SCN4A SCN8A	1.18e-06	6	90	3	ctd:C475726
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN3A SCN4A SCN8A	1.60e-08	10	89	4	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN3A SCN4A SCN8A	1.60e-08	10	89	4	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN3A SCN4A SCN8A	3.76e-08	12	89	4	DOID:0060170 (implicated_via_orthology)
Disease	Colorectal cancer	MLH3 TLR2 RAD54B	7.36e-05	27	89	3	cv:C0346629
Disease	COLORECTAL CANCER	MLH3 TLR2 RAD54B	7.36e-05	27	89	3	114500
Disease	Neoplasm of the large intestine	MLH3 TLR2 RAD54B	7.36e-05	27	89	3	cv:C0009404
Disease	Bipolar Disorder	CUX2 PBRM1 ACADS ESR1 TLR2 SCN8A DNAH8 S1PR1	9.89e-05	477	89	8	C0005586
Disease	Lennox-Gastaut syndrome	CUX2 SCN1A	1.34e-04	6	89	2	C0238111
Disease	Colorectal Carcinoma	EVC2 MLH3 ZNF560 RHPN2 TLR2 CCAR1 ABCC2 DNAH8 CUX1	2.71e-04	702	89	9	C0009402
Disease	gastritis	TCP10L CDC37	3.19e-04	9	89	2	EFO_0000217
Disease	MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (finding)	TIRAP TLR2	3.98e-04	10	89	2	C1834752
Disease	Mycobacterium tuberculosis, susceptibility to	TIRAP TLR2	3.98e-04	10	89	2	cv:C1834752
Disease	MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO	TIRAP TLR2	3.98e-04	10	89	2	607948
Disease	Drug habituation	XYLT1 PLA2R1 MACROD2 DNAH8	4.14e-04	115	89	4	C0013170
Disease	Drug abuse	XYLT1 PLA2R1 MACROD2 DNAH8	4.14e-04	115	89	4	C0013146
Disease	Prescription Drug Abuse	XYLT1 PLA2R1 MACROD2 DNAH8	4.14e-04	115	89	4	C4316881
Disease	Substance-Related Disorders	XYLT1 PLA2R1 MACROD2 DNAH8	4.14e-04	115	89	4	C0236969
Disease	Drug Use Disorders	XYLT1 PLA2R1 MACROD2 DNAH8	4.14e-04	115	89	4	C0013222
Disease	Drug Dependence	XYLT1 PLA2R1 MACROD2 DNAH8	4.14e-04	115	89	4	C1510472
Disease	Substance Dependence	XYLT1 PLA2R1 MACROD2 DNAH8	4.14e-04	115	89	4	C0038580
Disease	Substance Use Disorders	XYLT1 PLA2R1 MACROD2 DNAH8	4.14e-04	115	89	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	XYLT1 PLA2R1 MACROD2 DNAH8	4.14e-04	115	89	4	C0029231
Disease	Substance abuse problem	XYLT1 PLA2R1 MACROD2 DNAH8	4.28e-04	116	89	4	C0740858
Disease	Congenital myopathy (disorder)	SCN4A NEB	5.82e-04	12	89	2	C0270960
Disease	mood disorder	PBRM1 MACROD2	6.87e-04	13	89	2	EFO_0004247
Disease	hematologic cancer (implicated_via_orthology)	CUX2 CUX1	6.87e-04	13	89	2	DOID:2531 (implicated_via_orthology)
Disease	age at first sexual intercourse measurement	SPEG ESR1 RAD54B MACROD2 IGSF1 TERF1	1.08e-03	383	89	6	EFO_0009749
Disease	Endometrial Carcinoma	MLH3 ESR1 CUX1	1.36e-03	72	89	3	C0476089
Disease	chronotype measurement	DNAJC16 TET1 SCN8A MACROD2 CCDC87 FNBP4 TSHZ1 TRIM37 CUX1	1.38e-03	882	89	9	EFO_0008328
Disease	epilepsy (implicated_via_orthology)	SCN1A SCN3A SCN4A SCN8A	1.52e-03	163	89	4	DOID:1826 (implicated_via_orthology)
Disease	carnitine measurement	ACADS MARCHF8 NRK	1.59e-03	76	89	3	EFO_0010469
Disease	unipolar depression, memory performance, cognitive function measurement	TET1 TEX26	1.65e-03	20	89	2	EFO_0003761, EFO_0004874, EFO_0008354
Disease	serum gamma-glutamyl transferase measurement	CUX2 PBRM1 ACADS RHPN2 DNAJC16 MARCHF8 MACROD2 TSHZ1 ABCC2	1.76e-03	914	89	9	EFO_0004532
Disease	neuroimaging measurement, brain volume measurement	PBRM1 RHPN2 RASGRP3 MACROD2 WNK2	1.77e-03	286	89	5	EFO_0004346, EFO_0006930
Disease	vitiligo (is_implicated_in)	ESR1 TLR2	1.82e-03	21	89	2	DOID:12306 (is_implicated_in)
Disease	breast cancer, COVID-19	CUX2 ESR1	2.00e-03	22	89	2	MONDO_0007254, MONDO_0100096
Disease	anxiety disorder (implicated_via_orthology)	SCN1A SCN3A	2.00e-03	22	89	2	DOID:2030 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLTWRAAMLKDNKKP	ACADS	326	P16219
WSKLDPKTMKVNDLR	CCAR1	631	Q8IX12
MLSRPKPWSKLTQKG	CUX1	981	P39880
SMRVKHPKWKLRTKN	FBXW10	361	Q5XX13
KITLRLWNTKDKMSR	CFAP92	186	Q9ULG3
KAEKKLLASLEWLMP	FBXL6	176	Q8N531
KKMPSLPSLQATKSW	CCDC87	561	Q9NVE4
LIDIPMDSKKKALTW	C7orf31	206	Q8N865
VSDMLSRPKPWSKLT	CUX2	931	O14529
PLKMNLWKIATSKIR	BCO2	301	Q9BYV7
NSLKPLSMSQLKQWK	RAD54B	861	Q9Y620
EMKLPSTKKAEPLTW	HERV-K104	36	P61576
LKKENKMTWTPRNRS	IRX5	171	P78411
SMRVKHPKWKLRTKN	FBXW10B	361	O95170
RTPMSWSRIKKILKE	DGKK	206	Q5KSL6
KKIKLWTMPISSVRF	PBRM1	1071	Q86U86
PKSSKEMRESGWKLI	MTMR8	116	Q96EF0
LKSPLIRMTYKWKSI	LIPJ	176	Q5W064
AANPKVLKWMTELTK	FAM13B	601	Q9NYF5
KMILDLLKSLWKSST	PDCD4	381	Q53EL6
LWPSPLMIKRSKKNS	ESR1	291	P03372
KPNLTKLRKMAQAWR	MLH3	1416	Q9UHC1
LELKSAPSKKMWIKL	PDE1B	21	Q01064
APSKKMWIKLRSLLR	PDE1B	26	Q01064
EPMKLALSIEAKAWK	DNAH8	1066	Q96JB1
IKGKLSKLSLWMERL	DNAJC16	751	Q9Y2G8
SPKMSSLKLKKRWFV	MYO10	1406	Q9HD67
QLSVANMWKLRPLLK	POU5F2	171	Q8N7G0
MLWARKRKQSILKKT	EVC2	1211	Q86UK5
LKPLRKWEKLQMTSS	MARCHF8	136	Q5T0T0
SKIQIPKQEKWQRSM	KRIT1	261	O00522
TKKDVPKSWLMKALF	ABCC2	301	Q92887
TLRMKKLNWQKLPSN	INF2	561	Q27J81
LKPLRKWEKLQMTTS	MARCHF1	136	Q8TCQ1
KMRPWKSSTIIMLNL	OXGR1	61	Q96P68
SPVFVIQKKSSKWRM	ERVK-18	71	Q9QC07
IQKKSSKWRMLTDLR	ERVK-18	76	Q9QC07
LKDKTQMTWIRPSHK	IGSF1	71	Q8N6C5
NAKVKLVMWPLSSLR	DOK6	171	Q6PKX4
LWPFIKKNKLMSLLT	FNBP1	321	Q96RU3
RKKEKSMPWNVDTLS	CDC37	106	Q16543
KKGLEPWKRLRMQSK	CCDC191	751	Q8NCU4
PLTLTWTKKDSNMVL	KIRREL1	336	Q96J84
PKNWKEKMFTILERT	EXOC3	241	O60645
MVKSKLPNTVLGKIW	EHD1	471	Q9H4M9
VLLTIWKTKKFHRPM	S1PR1	66	P21453
RMLQWLATKSPKKED	HMCES	286	Q96FZ2
VPVLRTKKKFLEWMQ	PDIA5	366	Q14554
TLKNTEVKSAMRKLW	OR4C16	286	Q8NGL9
ENKSLMWTLLKQLRP	OSBPL5	366	Q9H0X9
PLNSILSWKEEMKGK	MACROD2	36	A1Z1Q3
KKILEMWKDIPSSIA	NRK	1491	Q7Z2Y5
WRVPSDLKMLKRLKT	TRIM37	666	O94972
MWRVKKLSLSLSPSP	SPAG5	1	Q96R06
KSKKVHRIVSKWMLP	RHBDL2	41	Q9NX52
VFKLAKSWPTLNMLI	SCN4A	676	P35499
LDKMKNPITKRWKHL	SH3BP4	921	Q9P0V3
KPMSLKIERISSWKT	TCP10L	166	Q8TDR4
TKMPSLVKKWQSIQR	FNBP4	941	Q8N3X1
ISKWVQLMVLSKPTP	RASGRP3	201	Q8IV61
LSWKSKLPLQTIMRL	HID1	686	Q8IV36
LSWMKEKIFSEVTPK	SIRT2	206	Q8IXJ6
LAKSWPTLNMLIKII	SCN3A	861	Q9NY46
PSAWSQEMVSLLKKL	STK32A	246	Q8WU08
CKWLTLSEVMKLLKS	RHPN2	566	Q8IUC4
VSMPSICKRKKVWLI	PLA2R1	931	Q13018
VFKLAKSWPTLNMLI	SCN1A	866	P35498
STKIWKPLAQTRSIM	TET1	1216	Q8NFU7
KSRTPDKMKNLSKSW	RHOU	236	Q7L0Q8
LALEWTSAMLTKKIK	WFDC8	31	Q8IUA0
KLETLETWVMPKKVF	XYLT1	711	Q86Y38
SLLEKRKLPWIMAKE	ZNF542P	21	Q5EBM4
ILTPWLFKATMLTDK	RALGAPA1	1126	Q6GYQ0
SWMKDKKSLRSEPSV	SPEG	2616	Q15772
MKDVPSWLKSLRLHK	SAMD4B	301	Q5PRF9
NMSPVSRLKKTWAKV	RASGEF1C	306	Q8N431
LMNPSQKKKRKHRLW	EZH1	486	Q92800
PKTKIFQFLKMTTWI	ERVK-11	436	Q9UQG0
MKIKNQPKERLVLSW	PXK	166	Q7Z7A4
VFKLAKSWPTLNMLI	SCN8A	851	Q9UQD0
GWVLPNTAMKKKVLL	RRAGB	31	Q5VZM2
KDRWRTMKKLKLISS	TERF1	421	P54274
RKKKTLTLPFSWQNM	ZNF770	401	Q6IQ21
MSEPGKLSQKIKVWL	TRPM1	881	Q7Z4N2
MADWFRQTLLKKPKK	TIRAP	21	P58753
LVTCLEQRKKPWSMK	ZNF355P	41	Q9NSJ1
WKIPASMKEVNKALS	TEX26	126	Q8N6G2
NWISKKKRTSPMTNL	WDSUB1	436	Q8N9V3
KVMKPKVLRSWCRQI	WNK2	291	Q9Y3S1
EEKKKLIATMRSKPW	TMC2	161	Q8TDI7
LLRWKMSTVTPNIVK	TTLL4	606	Q14679
KLRKIMNTKTYLEWP	TLR2	751	O60603
MKRSESWTLKKPKSV	TRIM22	256	Q8IYM9
EKTKRWSKPRKRSLM	TSHZ1	281	Q6ZSZ6
LPRVLQEWKMCLKTK	ZNF560	171	Q96MR9
LKKKEPGKRSQLWRM	VPS13D	3636	Q5THJ4
WLELQATKSKKPIML	MYO7A	1246	Q13402
AKWKAKIQSPVDMLS	NEB	4051	P20929