Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

VIPR2 OR8J2 OR11L1 OR2AK2 TPRA1 OR2M7 GPR22 GPR39 OR10V1 GPR135 GPR63 CHRM4 BDKRB1 OPRK1 GLP2R CXCR5 GHRHR TAS2R16 OR10H3 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1 OR56A4 TAS2R45 GPR132

7.25e-158849727GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

VIPR2 OR8J2 OR11L1 OR2AK2 TPRA1 OR2M7 GPR22 TRPA1 HTR3A GPR39 OR10V1 GPR135 ABCC9 GPR63 CHRM4 BDKRB1 OPRK1 GLP2R CXCR5 GHRHR TAS2R16 OR10H3 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1 OR56A4 TAS2R45 GPR132

7.35e-1313539730GO:0004888
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC36A1 SLC4A7 TRPA1 HTR3A CALHM1 ABCC9 TMC4 SLC1A3 SLC9A2 SLC9A3 KCNA1 SLC13A1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A SLC4A10 TMEM266 UNC80

1.14e-097939720GO:0015075
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC36A1 SLC4A7 TRPA1 HTR3A CALHM1 ABCC9 TMC4 SLC43A3 SLC1A3 ABCA8 ABCC6 SLC9A2 SLC9A3 KCNA1 SLC13A1 KCNC4 SLC24A2 KCNF1 SLC35B4 SCN1A SCN3A SLC4A10 TMEM266 UNC80

1.41e-0911809724GO:0022857
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC36A1 SLC4A7 TRPA1 HTR3A CALHM1 ABCC9 SLC1A3 SLC9A2 SLC9A3 KCNA1 SLC13A1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A SLC4A10 UNC80

2.84e-096649718GO:0008324
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC4A7 TRPA1 CALHM1 ABCC9 SLC1A3 SLC9A2 SLC9A3 KCNA1 SLC13A1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A SLC4A10

6.92e-094659715GO:0046873
GeneOntologyMolecularFunctiontransporter activity

SLC36A1 SLC4A7 TRPA1 HTR3A CALHM1 ABCC9 TMC4 SLC43A3 SLC1A3 ABCA8 ABCC6 SLC9A2 SLC9A3 KCNA1 SLC13A1 KCNC4 SLC24A2 KCNF1 SLC35B4 SCN1A SCN3A SLC4A10 TMEM266 UNC80

8.02e-0912899724GO:0005215
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC36A1 SLC4A7 TRPA1 CALHM1 ABCC9 SLC1A3 SLC9A2 SLC9A3 KCNA1 SLC13A1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A SLC4A10

5.53e-086279716GO:0022890
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC36A1 SLC4A7 TRPA1 CALHM1 ABCC9 SLC1A3 ABCC6 SLC9A2 SLC9A3 KCNA1 SLC13A1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A SLC4A10

1.30e-077589717GO:0015318
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC4A7 SLC1A3 SLC9A2 SLC9A3 SLC13A1 SLC24A2 SCN1A SCN3A SLC4A10

1.50e-07171979GO:0015081
GeneOntologyMolecularFunctionmonoatomic ion channel activity

TRPA1 HTR3A CALHM1 ABCC9 TMC4 KCNA1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A TMEM266 UNC80

3.40e-074599713GO:0005216
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TRPA1 HTR3A CALHM1 ABCC9 KCNA1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A UNC80

8.73e-073439711GO:0005261
GeneOntologyMolecularFunctionchannel activity

TRPA1 HTR3A CALHM1 ABCC9 TMC4 KCNA1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A TMEM266 UNC80

1.54e-065259713GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

TRPA1 HTR3A CALHM1 ABCC9 TMC4 KCNA1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A TMEM266 UNC80

1.57e-065269713GO:0022803
GeneOntologyMolecularFunctionvoltage-gated channel activity

TRPA1 CALHM1 ABCC9 KCNA1 KCNC4 KCNF1 SCN1A TMEM266

3.21e-06184978GO:0022832
GeneOntologyMolecularFunctiongated channel activity

TRPA1 HTR3A CALHM1 ABCC9 TMC4 KCNA1 KCNC4 KCNF1 SCN1A TMEM266

5.20e-063349710GO:0022836
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC36A1 SLC4A7 ABCC9 SLC1A3 SLC9A2 SLC9A3 SLC13A1 SLC24A2 SLC4A10

1.60e-05301979GO:0022853
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

ABCC9 SLC9A2 SLC9A3 KCNA1 KCNC4 SLC24A2 KCNF1

1.72e-05167977GO:0015079
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC36A1 SLC4A7 ABCC9 SLC1A3 ABCA8 ABCC6 SLC9A2 SLC9A3 SLC13A1 SLC24A2 SLC4A10

2.02e-054779711GO:0022804
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

TRPA1 CALHM1 ABCC9 KCNA1 KCNC4 KCNF1 SCN1A

3.00e-05182977GO:0005244
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC9A2 SLC9A3 SLC24A2 SLC4A10

5.58e-0543974GO:0140828
GeneOntologyMolecularFunctionG protein-coupled UTP receptor activity

P2RY2 P2RY4

6.98e-053972GO:0045030
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

KCNA1 KCNC4 SCN1A

7.19e-0517973GO:0099508
GeneOntologyMolecularFunctionsymporter activity

SLC36A1 SLC4A7 SLC1A3 SLC13A1 SLC24A2 SLC4A10

9.15e-05150976GO:0015293
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC36A1 SLC4A7 SLC1A3 SLC9A2 SLC9A3 SLC13A1 SLC24A2 SLC4A10

9.79e-05296978GO:0015291
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

TRPA1 CALHM1 ABCC9 KCNA1 KCNC4 KCNF1

9.85e-05152976GO:0022843
GeneOntologyMolecularFunctionsolute:potassium antiporter activity

SLC9A2 SLC9A3 SLC24A2

1.02e-0419973GO:0022821
GeneOntologyMolecularFunctionG protein-coupled pyrimidinergic nucleotide receptor activity

P2RY2 P2RY4

1.39e-044972GO:0071553
GeneOntologyMolecularFunctionpeptide hormone binding

VIPR2 GLP2R GHRHR CMKLR1

1.48e-0455974GO:0017046
GeneOntologyMolecularFunctionG protein-coupled chemoattractant receptor activity

CXCR5 CCR6 CMKLR1

2.66e-0426973GO:0001637
GeneOntologyMolecularFunctionchemokine receptor activity

CXCR5 CCR6 CMKLR1

2.66e-0426973GO:0004950
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC36A1 SLC4A7 SLC1A3 SLC13A1 SLC4A10

2.88e-04119975GO:0015294
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

KCNA1 KCNC4

3.46e-046972GO:1905030
GeneOntologyMolecularFunctiontelomerase inhibitor activity

ERCC4 MCRS1

3.46e-046972GO:0010521
GeneOntologyMolecularFunctionsodium:bicarbonate symporter activity

SLC4A7 SLC4A10

3.46e-046972GO:0008510
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

VIPR2 BDKRB1 OPRK1 GLP2R GHRHR

4.80e-04133975GO:0008528
GeneOntologyMolecularFunctionantiporter activity

SLC4A7 SLC9A2 SLC9A3 SLC24A2 SLC4A10

5.68e-04138975GO:0015297
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

SLC43A3 ABCA8 ABCC6

5.96e-0434973GO:0042910
GeneOntologyMolecularFunctionpeptide receptor activity

VIPR2 BDKRB1 OPRK1 GLP2R GHRHR

6.06e-04140975GO:0001653
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC4A7 SLC1A3 SLC13A1 SLC4A10

6.54e-0481974GO:0015370
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK1 DOCK4 MYCBP2 ARHGEF11 CHRM4 HERC1

9.24e-04231976GO:0005085
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC9 ABCC6

1.02e-0310972GO:0043225
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC4A7 ABCC9 ABCC6 SLC13A1 SLC4A10

1.48e-03171975GO:0015103
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

ABCC9 KCNA1 KCNC4 KCNF1

1.55e-03102974GO:0005249
GeneOntologyMolecularFunctionhormone binding

VIPR2 GLP2R GHRHR CMKLR1

1.60e-03103974GO:0042562
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC9 ABCA8 ABCC6

1.74e-0349973GO:0140359
GeneOntologyMolecularFunctionG protein-coupled purinergic nucleotide receptor activity

P2RY2 P2RY4

1.76e-0313972GO:0045028
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC4A7 SLC4A10

1.76e-0313972GO:0140410
GeneOntologyMolecularFunctionpotassium:proton antiporter activity

SLC9A2 SLC9A3

2.05e-0314972GO:0015386
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN3A

2.05e-0314972GO:0031402
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCA8 ABCC6

2.35e-0315972GO:0008559
GeneOntologyMolecularFunctionsodium:proton antiporter activity

SLC9A2 SLC9A3

2.68e-0316972GO:0015385
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC36A1 SLC4A7 SLC43A3 SLC1A3 SLC35B4 SLC4A10

3.07e-03293976GO:0008514
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

SLC36A1 ABCC6 SLC13A1

3.26e-0361973GO:1901682
GeneOntologyMolecularFunctionpotassium channel activity

ABCC9 KCNA1 KCNC4 KCNF1

3.53e-03128974GO:0005267
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

TRPA1 HTR3A CALHM1 ABCC9

4.85e-03140974GO:0099094
GeneOntologyMolecularFunctionolfactory receptor activity

OR8J2 OR11L1 OR2AK2 OR2M7 OR10V1 OR10H3 OR56A4

5.05e-03431977GO:0004984
GeneOntologyMolecularFunctionnucleotide receptor activity

P2RY2 P2RY4

5.06e-0322972GO:0016502
GeneOntologyMolecularFunctionpurinergic nucleotide receptor activity

P2RY2 P2RY4

5.06e-0322972GO:0001614
GeneOntologyMolecularFunctionphosphotransferase activity, for other substituted phosphate groups

PTDSS1 PIGO

5.06e-0322972GO:0016780
GeneOntologyMolecularFunctionC-C chemokine receptor activity

CXCR5 CCR6

5.53e-0323972GO:0016493
GeneOntologyMolecularFunctionC-C chemokine binding

CXCR5 CCR6

6.01e-0324972GO:0019957
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN1A SCN3A

7.04e-0326972GO:0005248
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN3A

7.04e-0326972GO:0031420
GeneOntologyMolecularFunctionmetal cation:proton antiporter activity

SLC9A2 SLC9A3

7.57e-0327972GO:0051139
GeneOntologyMolecularFunctionbitter taste receptor activity

TAS2R16 TAS2R45

7.57e-0327972GO:0033038
GeneOntologyMolecularFunctiondelayed rectifier potassium channel activity

KCNA1 KCNC4

8.13e-0328972GO:0005251
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC36A1 SLC1A3

8.71e-0329972GO:0005416
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC4A7 SLC4A10

1.05e-0232972GO:0015106
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC4A7 SLC4A10

1.05e-0232972GO:0005452
GeneOntologyMolecularFunctionchemokine binding

CXCR5 CCR6

1.12e-0233972GO:0019956
GeneOntologyMolecularFunctiontaste receptor activity

TAS2R16 TAS2R45

1.12e-0233972GO:0008527
GeneOntologyMolecularFunctioncytokine receptor activity

CXCR5 CCR6 CMKLR1

1.18e-0297973GO:0004896
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

VIPR2 OR8J2 OR11L1 OR2AK2 TPRA1 OR2M7 GPR22 GPR39 OR10V1 GPR135 GPR63 ARHGEF11 CHRM4 BDKRB1 OPRK1 GLP2R CXCR5 GHRHR TAS2R16 OR10H3 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1 OR56A4 TAS2R45 GPR132

2.62e-1113959728GO:0007186
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC36A1 SLC4A7 TRPA1 HTR3A CALHM1 GPR39 ABCC9 TMC4 SLC1A3 BDKRB1 ABCC6 OPRK1 SLC9A2 SLC9A3 KCNA1 SLC13A1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A ALG10 SLN SLC4A10 UNC80

3.85e-1111159725GO:0034220
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC36A1 SLC4A7 TRPA1 HTR3A CALHM1 GPR39 ABCC9 TMC4 SLC1A3 BDKRB1 ABCC6 OPRK1 SLC9A2 SLC9A3 KCNA1 SLC13A1 KCNC4 P2RY4 SLC24A2 KCNF1 SCN1A SCN3A ALG10 SLN SLC4A10 TMEM266 UNC80

1.06e-1013749727GO:0006811
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC36A1 SLC4A7 TRPA1 HTR3A CALHM1 GPR39 ABCC9 SLC1A3 BDKRB1 OPRK1 SLC9A2 SLC9A3 KCNA1 SLC13A1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A ALG10 SLN SLC4A10

2.25e-109229722GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC36A1 SLC4A7 TRPA1 CALHM1 GPR39 ABCC9 SLC1A3 BDKRB1 OPRK1 SLC9A2 SLC9A3 KCNA1 SLC13A1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A ALG10 SLN SLC4A10 UNC80

3.37e-109429722GO:0098655
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC36A1 SLC4A7 TRPA1 HTR3A CALHM1 GPR39 ABCC9 SLC1A3 BDKRB1 OPRK1 SLC9A2 SLC9A3 KCNA1 SLC13A1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A ALG10 SLN SLC4A10

1.41e-0910179722GO:0098660
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC36A1 SLC4A7 TRPA1 CALHM1 GPR39 ABCC9 SLC1A3 BDKRB1 OPRK1 SLC9A2 SLC9A3 KCNA1 SLC13A1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A ALG10 SLN SLC4A10 UNC80

1.49e-0811579722GO:0006812
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

SLC4A7 TRPA1 GPR39 TMEM199 XK GRINA SLC1A3 BDKRB1 ABCC6 SLC9A2 SLC9A3 KCNA1 P2RY2 P2RY4 SLC24A2 SLC4A10 UNC80

2.88e-087059717GO:0055080
GeneOntologyBiologicalProcessmetal ion transport

SLC4A7 TRPA1 CALHM1 GPR39 ABCC9 SLC1A3 BDKRB1 OPRK1 SLC9A2 SLC9A3 KCNA1 SLC13A1 KCNC4 SLC24A2 KCNF1 SCN1A SCN3A ALG10 SLN SLC4A10

3.33e-0810009720GO:0030001
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

SLC4A7 TRPA1 GPR39 TMEM199 XK GRINA SLC1A3 BDKRB1 ABCC6 SLC9A2 SLC9A3 KCNA1 P2RY2 P2RY4 SLC24A2 SLC4A10 UNC80

3.68e-087179717GO:0050801
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

ABCC9 SLC1A3 OPRK1 SLC9A2 SLC9A3 KCNA1 KCNC4 SLC24A2 KCNF1 ALG10

1.43e-072329710GO:0071805
GeneOntologyBiologicalProcesssensory perception

OR8J2 OR11L1 OR2AK2 SLC4A7 OR2M7 TRPA1 CALHM1 OR10V1 SLC1A3 ABCC6 OPRK1 TAS2R16 KCNA1 OR10H3 SCN1A ALG10 SLC4A10 OR56A4 TAS2R45

5.00e-0710729719GO:0007600
GeneOntologyBiologicalProcesspotassium ion transport

ABCC9 SLC1A3 OPRK1 SLC9A2 SLC9A3 KCNA1 KCNC4 SLC24A2 KCNF1 ALG10

6.19e-072729710GO:0006813
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

SLC4A7 TRPA1 GPR39 TMEM199 XK GRINA SLC1A3 BDKRB1 SLC9A2 SLC9A3 P2RY2 P2RY4 SLC24A2 SLC4A10

1.00e-066119714GO:0030003
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

SLC4A7 TRPA1 GPR39 TMEM199 XK GRINA SLC1A3 BDKRB1 SLC9A2 SLC9A3 P2RY2 P2RY4 SLC24A2 SLC4A10

1.24e-066229714GO:0006873
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC4A7 TRPA1 ABCC9 SLC1A3 ABCC6 SLC13A1 P2RY4 SLC4A10

2.43e-06183978GO:0006820
GeneOntologyBiologicalProcessintracellular chemical homeostasis

SLC4A7 TRPA1 GPR39 TMEM199 XK GRINA SLC1A3 BDKRB1 ABCC6 OPRK1 SLC9A2 SLC9A3 P2RY2 P2RY4 SLC24A2 SLC4A10

2.66e-068669716GO:0055082
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC4A7 SLC9A2 SLC9A3 SLC13A1 SLC24A2 SCN1A SCN3A SLC4A10

6.26e-06208978GO:0035725
GeneOntologyBiologicalProcessregulation of cellular pH

SLC4A7 GPR39 TMEM199 SLC9A2 SLC9A3 SLC4A10

8.18e-06101976GO:0030641
GeneOntologyBiologicalProcessneuronal action potential

TRPA1 KCNA1 KCNC4 SCN1A SCN3A

1.17e-0563975GO:0019228
GeneOntologyBiologicalProcesscellular homeostasis

SLC4A7 TRPA1 GPR39 TMEM199 XK GRINA SLC1A3 BDKRB1 ABCC6 OPRK1 SLC9A2 SLC9A3 P2RY2 P2RY4 SLC24A2 SLC4A10

1.28e-059819716GO:0019725
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR8J2 OR11L1 OR2AK2 OR2M7 TRPA1 OR10V1 TAS2R16 KCNA1 OR10H3 SCN1A OR56A4 TAS2R45

1.83e-055829712GO:0050906
GeneOntologyBiologicalProcesschemical homeostasis

SLC4A7 TRPA1 GPR39 TMEM199 XK GRINA SLC1A3 BDKRB1 ABCC6 OPRK1 SLC9A2 SLC9A3 KCNA1 P2RY2 P2RY4 SLC24A2 SLC4A10 UNC80

1.85e-0512499718GO:0048878
GeneOntologyBiologicalProcessregulation of pH

SLC4A7 GPR39 TMEM199 SLC9A2 SLC9A3 SLC4A10

2.19e-05120976GO:0006885
GeneOntologyBiologicalProcessinorganic ion homeostasis

TRPA1 GPR39 TMEM199 XK GRINA SLC1A3 BDKRB1 ABCC6 KCNA1 P2RY2 P2RY4 SLC24A2

3.50e-056229712GO:0098771
GeneOntologyBiologicalProcessphospholipid biosynthetic process

TMEM150A PTDSS1 DOLPP1 PIGU ABCA8 ATM FITM1 PIGO

3.90e-05268978GO:0008654
GeneOntologyBiologicalProcessaction potential

TRPA1 ABCC9 KCNA1 KCNC4 KCNF1 SCN1A SCN3A

4.60e-05201977GO:0001508
GeneOntologyBiologicalProcesssodium ion transport

SLC4A7 SLC9A2 SLC9A3 SLC13A1 SLC24A2 SCN1A SCN3A SLC4A10

4.68e-05275978GO:0006814
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR8J2 OR11L1 OR2AK2 OR2M7 TRPA1 CALHM1 OR10V1 TAS2R16 OR10H3 OR56A4 TAS2R45

5.23e-055479711GO:0007606
GeneOntologyBiologicalProcessregulation of intracellular pH

SLC4A7 TMEM199 SLC9A2 SLC9A3 SLC4A10

8.17e-0594975GO:0051453
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

SLC4A7 ABCC9 SLC1A3 ABCC6 SLC13A1 SLC4A10

8.56e-05153976GO:0098656
GeneOntologyBiologicalProcesscalcium ion homeostasis

TRPA1 GPR39 XK GRINA BDKRB1 ABCC6 P2RY2 P2RY4 SLC24A2

9.12e-05389979GO:0055074
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR8J2 OR11L1 OR2AK2 OR2M7 TRPA1 OR10V1 TAS2R16 OR10H3 OR56A4 TAS2R45

9.52e-054859710GO:0050907
GeneOntologyBiologicalProcessimport across plasma membrane

SLC36A1 ABCC9 ARHGEF11 SLC1A3 SLC9A2 SLC9A3 SLC24A2

1.07e-04230977GO:0098739
GeneOntologyBiologicalProcesscellular response to ATP

ABCC9 P2RY2 P2RY4

1.26e-0421973GO:0071318
GeneOntologyBiologicalProcessdetection of stimulus

OR8J2 OR11L1 OR2AK2 OR2M7 TRPA1 OR10V1 TAS2R16 KCNA1 OR10H3 SCN1A OR56A4 TAS2R45

1.45e-047229712GO:0051606
GeneOntologyBiologicalProcessorganic anion transport

SLC36A1 SLC4A7 CALHM1 SLC43A3 ARHGEF11 SLC1A3 ABCC6 P2RY2 SLC35B4 SLC4A10

1.55e-045159710GO:0015711
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR8J2 OR11L1 OR2AK2 OR2M7 TRPA1 OR10V1 TAS2R16 OR10H3 OR56A4 TAS2R45

1.79e-045249710GO:0009593
GeneOntologyBiologicalProcesstransmission of nerve impulse

TRPA1 KCNA1 KCNC4 SCN1A SCN3A

1.87e-04112975GO:0019226
GeneOntologyBiologicalProcessinorganic anion transport

SLC4A7 SLC1A3 ABCC6 SLC13A1 P2RY4 SLC4A10

2.08e-04180976GO:0015698
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception of pain

TRPA1 KCNA1 SCN1A

2.42e-0426973GO:0050966
GeneOntologyBiologicalProcessmuscle system process

DOCK4 TRPA1 ABCC9 ARHGEF11 GTF2IRD2B KCNA1 SCN1A SCN3A SLN GTF2IRD2

2.52e-045479710GO:0003012
GeneOntologyBiologicalProcessintracellular calcium ion homeostasis

TRPA1 GPR39 XK GRINA BDKRB1 P2RY2 P2RY4 SLC24A2

2.93e-04359978GO:0006874
GeneOntologyBiologicalProcessphospholipase C-activating G protein-coupled receptor signaling pathway

OPRK1 P2RY2 P2RY4 LPAR6 CMKLR1

4.14e-04133975GO:0007200
GeneOntologyBiologicalProcessregulation of presynaptic membrane potential

HTR3A KCNA1 SCN1A

4.53e-0432973GO:0099505
GeneOntologyBiologicalProcessneuron cellular homeostasis

GPR39 P2RY2 P2RY4 SLC24A2

6.65e-0484974GO:0070050
GeneOntologyBiologicalProcesspositive regulation of cytosolic calcium ion concentration

BDKRB1 CXCR5 P2RY2 P2RY4 CCR6 CMKLR1

6.66e-04224976GO:0007204
GeneOntologyBiologicalProcessphospholipid metabolic process

TMEM150A PTDSS1 DOLPP1 PIGU ABCA8 ATM FITM1 PIGO

7.04e-04410978GO:0006644
GeneOntologyBiologicalProcessnegative regulation of telomere capping

ERCC4 ATM

7.71e-049972GO:1904354
GeneOntologyBiologicalProcessresponse to ATP

ABCC9 P2RY2 P2RY4

8.78e-0440973GO:0033198
GeneOntologyBiologicalProcessmembrane lipid biosynthetic process

ST6GALNAC6 PIGU ABCA8 CYP4F22 PIGO

8.80e-04157975GO:0046467
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

SLC4A7 TRPA1 SLC1A3 KCNA1 SCN1A ALG10

9.13e-04238976GO:0050954
GeneOntologyBiologicalProcessnegative regulation of telomere maintenance

ERCC4 MCRS1 ATM

1.01e-0342973GO:0032205
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception of pain

TRPA1 KCNA1 SCN1A

1.09e-0343973GO:0062149
GeneOntologyBiologicalProcessmacromolecule glycosylation

DOLPP1 ST6GALNAC6 STT3A GALNT9 ALG10 SLC4A10

1.23e-03252976GO:0043413
GeneOntologyBiologicalProcessprotein glycosylation

DOLPP1 ST6GALNAC6 STT3A GALNT9 ALG10 SLC4A10

1.23e-03252976GO:0006486
GeneOntologyBiologicalProcessregulation of membrane potential

TRPA1 HTR3A GPR39 ABCC9 KCNA1 KCNC4 KCNF1 SCN1A SCN3A

1.28e-03559979GO:0042391
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

OR2M7 CALHM1 TMEM199 PTDSS1 WDR81 XK DOLPP1 PIGU ABCC6 STT3A GHRHR SLC35B4 FURIN ALG10 SLN CYP4F22 FITM1 TRAM2 PIGO

1.73e-05132710119GO:0042175
GeneOntologyCellularComponentcation channel complex

HTR3A ABCC9 KCNA1 KCNC4 KCNF1 SCN1A SCN3A UNC80

1.86e-052351018GO:0034703
GeneOntologyCellularComponentapical plasma membrane

SLC36A1 SLC4A7 TRPA1 ABCC6 SLC9A2 SLC9A3 KCNA1 SLC13A1 P2RY2 P2RY4 SLC4A10

2.36e-0548710111GO:0016324
GeneOntologyCellularComponentbasolateral plasma membrane

SLC4A7 CALHM1 SLC43A3 SLC1A3 ABCA8 ABCC6 P2RY2 P2RY4 SLC4A10

2.51e-053201019GO:0016323
GeneOntologyCellularComponentendoplasmic reticulum membrane

OR2M7 CALHM1 TMEM199 PTDSS1 WDR81 XK DOLPP1 PIGU ABCC6 STT3A SLC35B4 FURIN ALG10 SLN CYP4F22 FITM1 TRAM2 PIGO

4.31e-05129310118GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

OR2M7 CALHM1 TMEM199 PTDSS1 WDR81 XK DOLPP1 PIGU ABCC6 STT3A SLC35B4 FURIN ALG10 SLN CYP4F22 FITM1 TRAM2 PIGO

4.58e-05129910118GO:0098827
GeneOntologyCellularComponentbasal plasma membrane

SLC4A7 CALHM1 SLC43A3 SLC1A3 ABCA8 ABCC6 P2RY2 P2RY4 SLC4A10

5.50e-053541019GO:0009925
GeneOntologyCellularComponentpresynaptic membrane

HTR3A CHRM4 OPRK1 KCNA1 P2RY2 KCNC4 P2RY4 SCN1A

5.99e-052771018GO:0042734
GeneOntologyCellularComponentbasal part of cell

SLC4A7 CALHM1 SLC43A3 SLC1A3 ABCA8 ABCC6 P2RY2 P2RY4 SLC4A10

9.08e-053781019GO:0045178
GeneOntologyCellularComponentapical part of cell

SLC36A1 SLC4A7 TRPA1 ABCC6 SLC9A2 SLC9A3 KCNA1 SLC13A1 P2RY2 P2RY4 SLC4A10

1.36e-0459210111GO:0045177
GeneOntologyCellularComponentpresynapse

HTR3A ATCAY SLC35G2 CHRM4 OPRK1 KCNA1 P2RY2 KCNC4 P2RY4 SLC24A2 SCN1A SLC4A10 ATM

3.38e-0488610113GO:0098793
GeneOntologyCellularComponentaxon

TRPA1 HTR3A MYCBP2 ATCAY CHRM4 OPRK1 KCNA1 KCNC4 SCN1A SCN3A SLC4A10 UNC80 DYNC1I1

3.57e-0489110113GO:0030424
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN3A UNC80

3.65e-04291013GO:0034706
GeneOntologyCellularComponentmonoatomic ion channel complex

HTR3A ABCC9 KCNA1 KCNC4 KCNF1 SCN1A SCN3A UNC80

4.97e-043781018GO:0034702
GeneOntologyCellularComponentneuron projection terminus

ATCAY CHRM4 OPRK1 KCNA1 KCNC4 SLC4A10

9.44e-042331016GO:0044306
GeneOntologyCellularComponenttransmembrane transporter complex

HTR3A TMEM199 ABCC9 KCNA1 KCNC4 KCNF1 SCN1A SCN3A UNC80

9.75e-045231019GO:1902495
GeneOntologyCellularComponenttransporter complex

HTR3A TMEM199 ABCC9 KCNA1 KCNC4 KCNF1 SCN1A SCN3A UNC80

1.38e-035501019GO:1990351
GeneOntologyCellularComponentpotassium channel complex

ABCC9 KCNA1 KCNC4 KCNF1

1.63e-031041014GO:0034705
GeneOntologyCellularComponentsynaptic membrane

HTR3A CHRM4 OPRK1 LRFN4 KCNA1 P2RY2 KCNC4 P2RY4 SCN1A

2.06e-035831019GO:0097060
GeneOntologyCellularComponentsarcolemma

ABCC9 CHRM4 OPRK1 GHRHR SCN1A

2.30e-031901015GO:0042383
GeneOntologyCellularComponentneuronal cell body

HTR3A SLC1A3 CHRM4 OPRK1 KCNA1 KCNC4 SCN1A SCN3A SLC4A10 TMEM266 MCRS1

2.33e-0383510111GO:0043025
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN3A

3.00e-03171012GO:0001518
GeneOntologyCellularComponentaxon terminus

CHRM4 OPRK1 KCNA1 KCNC4 SLC4A10

3.54e-032101015GO:0043679
GeneOntologyCellularComponentcluster of actin-based cell projections

DOCK4 SLC4A7 TRPA1 SLC9A2 SLC9A3

4.57e-032231015GO:0098862
GeneOntologyCellularComponentperikaryon

OPRK1 KCNA1 SLC4A10 TMEM266 MCRS1

4.57e-032231015GO:0043204
DomainGPCR_Rhodpsn_7TM

OR11L1 OR2AK2 OR2M7 GPR22 GPR39 OR10V1 GPR135 GPR63 CHRM4 BDKRB1 OPRK1 CXCR5 OR10H3 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1 OR56A4 GPR132

2.33e-106709820IPR017452
Domain7tm_1

OR11L1 OR2AK2 OR2M7 GPR22 GPR39 OR10V1 GPR135 GPR63 CHRM4 BDKRB1 OPRK1 CXCR5 OR10H3 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1 OR56A4 GPR132

2.80e-106779820PF00001
DomainG_PROTEIN_RECEP_F1_1

OR11L1 OR2AK2 OR2M7 GPR22 GPR39 OR10V1 GPR135 GPR63 CHRM4 BDKRB1 OPRK1 CXCR5 OR10H3 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1 OR56A4 GPR132

3.44e-106859820PS00237
DomainG_PROTEIN_RECEP_F1_2

OR11L1 OR2AK2 OR2M7 GPR22 GPR39 OR10V1 GPR135 GPR63 CHRM4 BDKRB1 OPRK1 CXCR5 OR10H3 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1 OR56A4 GPR132

4.00e-106919820PS50262
DomainGPCR_Rhodpsn

OR11L1 OR2AK2 OR2M7 GPR22 GPR39 OR10V1 GPR135 GPR63 CHRM4 BDKRB1 OPRK1 CXCR5 OR10H3 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1 OR56A4 GPR132

4.11e-106929820IPR000276
DomainChannel_four-helix_dom

KCNA1 KCNC4 KCNF1 SCN1A SCN3A TMEM266

5.23e-0757986IPR027359
Domain-

KCNA1 KCNC4 KCNF1 SCN1A SCN3A TMEM266

5.23e-07579861.20.120.350
DomainIon_trans_dom

TRPA1 KCNA1 KCNC4 KCNF1 SCN1A SCN3A TMEM266

2.29e-06114987IPR005821
DomainIon_trans

TRPA1 KCNA1 KCNC4 KCNF1 SCN1A SCN3A TMEM266

2.29e-06114987PF00520
Domain-

GTF2IRD2B GTF2IRD2

1.62e-0449823.90.1460.10
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.62e-044982PS51139
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.62e-044982PF02946
DomainGTF2I

GTF2IRD2B GTF2IRD2

1.62e-044982IPR004212
DomainDOCK_N

DOCK1 DOCK4

2.70e-045982PF16172
DomainDOCK_N

DOCK1 DOCK4

2.70e-045982IPR032376
DomainAnion_exchange

SLC4A7 SLC4A10

2.70e-045982IPR001717
DomainHormR

VIPR2 GLP2R GHRHR

2.96e-0425983SM00008
DomainK_chnl_volt-dep_Kv

KCNA1 KCNC4 KCNF1

3.74e-0427983IPR003968
DomainNa_trans_cytopl

SCN1A SCN3A

4.03e-046982PF11933
DomainNa_trans_cytopl

SCN1A SCN3A

4.03e-046982IPR024583
DomainHRM

VIPR2 GLP2R GHRHR

4.17e-0428983PF02793
DomainANION_EXCHANGER_2

SLC4A7 SLC4A10

5.63e-047982PS00220
DomainANION_EXCHANGER_1

SLC4A7 SLC4A10

5.63e-047982PS00219
DomainVG_K_chnl

KCNA1 KCNC4 KCNF1

6.82e-0433983IPR028325
DomainGPCR_2_secretin-like_CS

VIPR2 GLP2R GHRHR

7.45e-0434983IPR017983
DomainNaH_exchanger

SLC9A2 SLC9A3

9.58e-049982IPR004709
DomainBand3_cytoplasmic_dom

SLC4A7 SLC4A10

9.58e-049982IPR013769
DomainBand_3_cyto

SLC4A7 SLC4A10

9.58e-049982PF07565
Domain-

SLC4A7 SLC4A10

9.58e-0499823.40.1100.10
DomainNa_channel_asu

SCN1A SCN3A

1.19e-0310982IPR001696
DomainHCO3_cotransp

SLC4A7 SLC4A10

1.19e-0310982PF00955
DomainHCO3_transpt_C

SLC4A7 SLC4A10

1.19e-0310982IPR011531
DomainNa_trans_assoc

SCN1A SCN3A

1.19e-0310982IPR010526
DomainPTrfase/Anion_transptr

SLC4A7 SLC4A10

1.19e-0310982IPR016152
DomainHCO3_transpt_euk

SLC4A7 SLC4A10

1.19e-0310982IPR003020
DomainNa_trans_assoc

SCN1A SCN3A

1.19e-0310982PF06512
DomainG_PROTEIN_RECEP_F2_1

VIPR2 GLP2R GHRHR

1.20e-0340983PS00649
DomainGPCR_2_extracellular_dom

VIPR2 GLP2R GHRHR

1.20e-0340983IPR001879
DomainG_PROTEIN_RECEP_F2_3

VIPR2 GLP2R GHRHR

1.20e-0340983PS50227
DomainDOCK_C

DOCK1 DOCK4

1.45e-0311982IPR010703
DomainCation/H_exchanger_CPA1

SLC9A2 SLC9A3

1.45e-0311982IPR018422
DomainDHR-1_domain

DOCK1 DOCK4

1.45e-0311982IPR027007
DomainDHR_2

DOCK1 DOCK4

1.45e-0311982PS51651
DomainDHR_1

DOCK1 DOCK4

1.45e-0311982PS51650
DomainDOCK-C2

DOCK1 DOCK4

1.45e-0311982PF14429
DomainDHR-2

DOCK1 DOCK4

1.45e-0311982IPR027357
DomainXK_rel

XK XKR3

1.45e-0311982IPR018629
DomainDHR-2

DOCK1 DOCK4

1.45e-0311982PF06920
DomainDOCK

DOCK1 DOCK4

1.45e-0311982IPR026791
DomainXK-related

XK XKR3

1.45e-0311982PF09815
DomainABC_tran

ABCC9 ABCA8 ABCC6

2.04e-0348983PF00005
DomainABC_TRANSPORTER_2

ABCC9 ABCA8 ABCC6

2.04e-0348983PS50893
DomainABC_TRANSPORTER_1

ABCC9 ABCA8 ABCC6

2.17e-0349983PS00211
DomainG_PROTEIN_RECEP_F2_2

VIPR2 GLP2R GHRHR

2.30e-0350983PS00650
Domain7tm_2

VIPR2 GLP2R GHRHR

2.30e-0350983PF00002
DomainABC_transporter-like

ABCC9 ABCA8 ABCC6

2.30e-0350983IPR003439
DomainNa_H_Exchanger

SLC9A2 SLC9A3

2.38e-0314982PF00999
DomainCation/H_exchanger

SLC9A2 SLC9A3

2.38e-0314982IPR006153
DomainBTB_2

KCNA1 KCNC4 KCNF1

2.71e-0353983PF02214
DomainT1-type_BTB

KCNA1 KCNC4 KCNF1

2.71e-0353983IPR003131
DomainGPCR_2_secretin-like

VIPR2 GLP2R GHRHR

3.86e-0360983IPR000832
DomainGPCR_2-like

VIPR2 GLP2R GHRHR

3.86e-0360983IPR017981
DomainG_PROTEIN_RECEP_F2_4

VIPR2 GLP2R GHRHR

4.04e-0361983PS50261
DomainRCC1

MYCBP2 HERC1

4.87e-0320982PF00415
PathwayREACTOME_GPCR_LIGAND_BINDING

VIPR2 GPR39 XK CHRM4 BDKRB1 OPRK1 GLP2R CXCR5 GHRHR TAS2R16 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1 TAS2R45 GPR132

2.17e-104308017MM15160
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

GPR22 GPR39 GPR63 CHRM4 BDKRB1 OPRK1 CXCR5 OR10H3 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1

2.22e-092608013M39397
PathwayWP_GPCRS_NONODORANT

VIPR2 CHRM4 BDKRB1 OPRK1 GLP2R CXCR5 GHRHR TAS2R16 P2RY2 P2RY4 LPAR6 CCR6 GPR132

2.93e-092668013MM15843
PathwayREACTOME_GPCR_LIGAND_BINDING

VIPR2 GPR39 XK CHRM4 BDKRB1 OPRK1 GLP2R CXCR5 GHRHR TAS2R16 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1 GPR132

5.52e-094638016M507
PathwayREACTOME_SIGNALING_BY_GPCR

VIPR2 GPR39 XK ARHGEF11 CHRM4 BDKRB1 OPRK1 GLP2R CXCR5 GHRHR TAS2R16 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1 TAS2R45 GPR132

1.55e-086468018MM14962
PathwayREACTOME_SIGNALING_BY_GPCR

VIPR2 GPR39 XK ARHGEF11 CHRM4 BDKRB1 OPRK1 GLP2R CXCR5 GHRHR TAS2R16 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1 GPR132

3.13e-077028017M746
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

GPR39 XK CHRM4 BDKRB1 OPRK1 CXCR5 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1 GPR132

3.21e-073308012M18334
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

GPR39 XK CHRM4 BDKRB1 OPRK1 CXCR5 P2RY2 P2RY4 LPAR6 CCR6 CMKLR1 GPR132

3.53e-073338012MM14963
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

GPR63 CHRM4 BDKRB1 OPRK1 CXCR5 P2RY2 P2RY4 CCR6 CMKLR1

1.03e-06186809MM15994
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC36A1 SLC4A7 SLC1A3 SLC9A2 SLC9A3 SLC24A2 SLC4A10

2.55e-06108807M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC36A1 SLC4A7 SLC1A3 SLC9A2 SLC9A3 SLC24A2 SLC4A10

2.72e-06109807MM15074
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC36A1 SLC4A7 TRPA1 ABCC9 SLC1A3 ABCA8 ABCC6 SLC9A2 SLC9A3 SLC13A1 SLC24A2 SLC35B4 FURIN SLN SLC4A10 UNC80

3.03e-067368016M27287
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC36A1 SLC4A7 TRPA1 ABCC9 SLC1A3 ABCA8 ABCC6 SLC9A2 SLC9A3 SLC13A1 SLC24A2 SLC35B4 FURIN SLC4A10 UNC80

5.54e-066818015MM14985
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC36A1 SLC4A7 SLC1A3 SLC9A2 SLC9A3 SLC13A1 SLC24A2 SLC35B4 SLC4A10

7.84e-06238809MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC36A1 SLC4A7 SLC1A3 SLC9A2 SLC9A3 SLC13A1 SLC24A2 SLC35B4 SLC4A10

1.13e-05249809M5988
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

VIPR2 CHRM4 BDKRB1 OPRK1 GLP2R GHRHR P2RY2 P2RY4 LPAR6

2.28e-05272809M13380
PathwayWP_NUCLEOTIDE_GPCRS

P2RY2 P2RY4 LPAR6

2.81e-0511803M39422
PathwayREACTOME_P2Y_RECEPTORS

P2RY2 P2RY4 LPAR6

2.81e-0511803MM15049
PathwayWP_GPCRS_ODORANT

TPRA1 GPR22 GPR135 GPR63 OR10H3 CMKLR1 TAS2R45

2.99e-05157807MM15872
PathwayREACTOME_P2Y_RECEPTORS

P2RY2 P2RY4 LPAR6

3.73e-0512803M10960
PathwayWP_NUCLEOTIDE_GPCRS

P2RY2 P2RY4 LPAR6

3.73e-0512803MM15953
PathwayREACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS

P2RY2 P2RY4 LPAR6

9.34e-0516803M6786
PathwayREACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS

P2RY2 P2RY4 LPAR6

9.34e-0516803MM15050
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

CHRM4 BDKRB1 OPRK1 CXCR5 TAS2R16 P2RY4 CCR6 TAS2R45

2.29e-04289808MM15057
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

VIPR2 GLP2R GHRHR

3.27e-0424803M39643
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

VIPR2 GLP2R GHRHR

3.27e-0424803MM15992
PathwayWP_GPCRS_PEPTIDE

BDKRB1 OPRK1 CXCR5 CCR6

6.64e-0470804MM15959
PathwayWP_PURINERGIC_SIGNALING

P2RY2 P2RY4 LPAR6

8.49e-0433803M39855
PathwayREACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS

VIPR2 GLP2R GHRHR

8.49e-0433803MM15066
PathwayREACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS

VIPR2 GLP2R GHRHR

8.49e-0433803M10322
PathwayWP_PEPTIDE_GPCRS

BDKRB1 OPRK1 CXCR5 CCR6

8.61e-0475804M39696
PathwayREACTOME_SODIUM_PROTON_EXCHANGERS

SLC9A2 SLC9A3

1.12e-039802M27337
PathwayREACTOME_SODIUM_PROTON_EXCHANGERS

SLC9A2 SLC9A3

1.12e-039802MM15079
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A7 SLC4A10

1.39e-0310802M27335
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A7 SLC4A10

1.39e-0310802MM15073
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNA1 KCNC4 KCNF1

1.61e-0341803MM14546
PathwayKEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG6_TO_OST

STT3A ALG10

1.69e-0311802M47614
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNA1 KCNC4 KCNF1

1.84e-0343803M1056
PathwayKEGG_ABC_TRANSPORTERS

ABCC9 ABCA8 ABCC6

1.97e-0344803M11911
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

CHRM4 BDKRB1 OPRK1 CXCR5 TAS2R16 P2RY4 CCR6

2.01e-03314807M600
PathwayKEGG_N_GLYCAN_BIOSYNTHESIS

DOLPP1 STT3A ALG10

2.24e-0346803M11079
PathwayREACTOME_POTASSIUM_CHANNELS

ABCC9 KCNA1 KCNC4 KCNF1

2.32e-0398804MM14545
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

CALHM1 TAS2R16 SCN3A

2.38e-0347803M42524
PathwayREACTOME_POTASSIUM_CHANNELS

ABCC9 KCNA1 KCNC4 KCNF1

2.78e-03103804M1073
PathwayREACTOME_NEURONAL_SYSTEM

HTR3A ABCC9 SLC1A3 LRFN4 KCNA1 KCNC4 KCNF1

2.89e-03335807MM14503
PathwayREACTOME_SENSORY_PERCEPTION

OR8J2 OR11L1 OR2AK2 OR2M7 CALHM1 OR10V1 TAS2R16 OR10H3 SCN3A OR56A4

3.10e-036368010M41834
Pubmed

Dissociation of heterotrimeric g proteins in cells.

VIPR2 CHRM4 BDKRB1 OPRK1 CXCR5 GHRHR P2RY2 P2RY4 LPAR6 CCR6

1.30e-101791011018577758
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

VIPR2 CHRM4 BDKRB1 OPRK1 GLP2R GHRHR P2RY2 P2RY4 LPAR6 CCR6

3.85e-102001011018240029
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

ABCC9 KCNA1 KCNC4 KCNF1 SCN1A SCN3A

3.39e-06139101616985003
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

TPRA1 GPR22 GPR39 GPR135 GLP2R

3.55e-0679101512679517
Pubmed

NHE2-mediated bicarbonate reabsorption in the distal tubule of NHE3 null mice.

SLC9A2 SLC9A3

8.35e-062101215604231
Pubmed

Distribution of P2Y receptor subtypes on haematopoietic cells.

P2RY2 P2RY4

8.35e-06210129535005
Pubmed

Loss of the NHE2 Na(+)/H(+) exchanger has no apparent effect on diarrheal state of NHE3-deficient mice.

SLC9A2 SLC9A3

8.35e-062101211705743
Pubmed

K+ secretion activated by luminal P2Y2 and P2Y4 receptors in mouse colon.

P2RY2 P2RY4

8.35e-062101215718265
Pubmed

Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion.

SLC9A2 SLC9A3

8.35e-06210129502765
Pubmed

Extracellular ATP activates MAP kinase cascades through a P2Y purinergic receptor in the human intestinal Caco-2 cell line.

P2RY2 P2RY4

8.35e-062101219836435
Pubmed

High-resolution molecular genomic autopsy reveals complex sudden unexpected death in epilepsy risk profile.

KCNA1 SCN1A

8.35e-062101224372310
Pubmed

Intestinal NaCl transport in NHE2 and NHE3 knockout mice.

SLC9A2 SLC9A3

8.35e-062101211960774
Pubmed

Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2.

SLC9A2 SLC9A3

8.35e-062101211553519
Pubmed

Novel amiloride-sensitive sodium-dependent proton secretion in the mouse proximal convoluted tubule.

SLC9A2 SLC9A3

8.35e-062101210772659
Pubmed

Intestinal brush-border Na+/H+ exchanger-3 drives H+-coupled iron absorption in the mouse.

SLC9A2 SLC9A3

8.35e-062101227390324
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

8.35e-062101224990319
Pubmed

The transient receptor potential ankyrin-1 mediates mechanical hyperalgesia induced by the activation of B1 receptor in mice.

TRPA1 BDKRB1

8.35e-062101227823962
Pubmed

Spreading depolarization in the brainstem mediates sudden cardiorespiratory arrest in mouse SUDEP models.

KCNA1 SCN1A

8.35e-062101225855492
Pubmed

ATP modulates transcription factors through P2Y2 and P2Y4 receptors via PKC/MAPKs and PKC/Src pathways in MCF-7 cells.

P2RY2 P2RY4

8.35e-062101219900397
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

8.35e-062101227690330
Pubmed

Chronic continuous hypoxia decreases the expression of SLC4A7 (NBCn1) and SLC4A10 (NCBE) in mouse brain.

SLC4A7 SLC4A10

8.35e-062101217928512
Pubmed

Indirect regulation of the intestinal H+-coupled amino acid transporter hPAT1 (SLC36A1).

SLC36A1 SLC9A3

8.35e-062101215754324
Pubmed

Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.

GTF2IRD2B GTF2IRD2

8.35e-062101215388857
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

8.35e-062101223965409
Pubmed

Intestinal distribution of human Na+/H+ exchanger isoforms NHE-1, NHE-2, and NHE-3 mRNA.

SLC9A2 SLC9A3

8.35e-06210128843774
Pubmed

HCO3- salvage mechanisms in the submandibular gland acinar and duct cells.

SLC9A2 SLC9A3

8.35e-062101211139574
Pubmed

Human duodenal mucosal brush border Na(+)/H(+) exchangers NHE2 and NHE3 alter net bicarbonate movement.

SLC9A2 SLC9A3

8.35e-062101211408268
Pubmed

Disruption of Na+,HCO₃⁻ cotransporter NBCn1 (slc4a7) inhibits NO-mediated vasorelaxation, smooth muscle Ca²⁺ sensitivity, and hypertension development in mice.

SLC4A7 SLC9A3

8.35e-062101221947296
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN3A

2.50e-053101212610651
Pubmed

The Na+/H+ exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE3 upregulation.

SLC9A2 SLC9A3

2.50e-053101214962844
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN3A

2.50e-053101233895391
Pubmed

Autocrine and paracrine roles for ATP and serotonin in mouse taste buds.

P2RY2 P2RY4

2.50e-053101219890001
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN3A

2.50e-053101223859570
Pubmed

NHE2X3 DKO mice exhibit gender-specific NHE8 compensation.

SLC9A2 SLC9A3

2.50e-053101221252044
Pubmed

Critical role for NHE1 in intracellular pH regulation in pancreatic acinar cells.

SLC9A2 SLC9A3

2.50e-053101212842825
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN3A

2.50e-053101218784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN3A

2.50e-053101217544618
Pubmed

MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment.

MCRS1 DYNC1I1

2.50e-053101227263857
Pubmed

GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.

SCN1A SCN3A

2.50e-053101227816501
Pubmed

Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.

GTF2IRD2B GTF2IRD2

2.50e-053101215100712
Pubmed

Cloning and functional characterization of two murine uridine nucleotide receptors reveal a potential target for correcting ion transport deficiency in cystic fibrosis gallbladder.

P2RY2 P2RY4

2.50e-053101211259526
Pubmed

Loss of nucleotide regulation of epithelial chloride transport in the jejunum of P2Y4-null mice.

P2RY2 P2RY4

2.50e-053101212644577
Pubmed

Interferon-gamma suppresses Na+ -H+ exchanger in cultured human endolymphatic sac epithelial cells.

SLC9A2 SLC9A3

2.50e-053101219479940
Pubmed

Human keratinocytes express multiple P2Y-receptors: evidence for functional P2Y1, P2Y2, and P2Y4 receptors.

P2RY2 P2RY4

2.50e-053101212603858
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN3A

2.50e-053101214973256
Pubmed

Functional coupling of the downregulated in adenoma Cl-/base exchanger DRA and the apical Na+/H+ exchangers NHE2 and NHE3.

SLC9A2 SLC9A3

2.50e-053101219056765
Pubmed

Genetic Variants Associated with Episodic Ataxia in Korea.

SLC1A3 KCNA1

2.50e-053101229062094
Pubmed

Functional expression and intracellular signaling of UTP-sensitive P2Y receptors in theca-interstitial cells.

P2RY2 P2RY4

2.50e-053101220630102
Pubmed

NHE2 is the main apical NHE in mouse colonic crypts but an alternative Na+-dependent acid extrusion mechanism is upregulated in NHE2-null mice.

SLC9A2 SLC9A3

2.50e-053101216690903
Pubmed

kappa Opioid receptor interacts with Na(+)/H(+)-exchanger regulatory factor-1/Ezrin-radixin-moesin-binding phosphoprotein-50 (NHERF-1/EBP50) to stimulate Na(+)/H(+) exchange independent of G(i)/G(o) proteins.

OPRK1 SLC9A3

2.50e-053101215070904
Pubmed

Defective fluid secretion and NaCl absorption in the parotid glands of Na+/H+ exchanger-deficient mice.

SLC9A2 SLC9A3

2.50e-053101211358967
Pubmed

Morphological adaptation with preserved proliferation/transporter content in the colon of patients with short bowel syndrome.

SLC9A2 SLC9A3

2.50e-053101219389806
Pubmed

Targeted disruption of the Nhe1 gene prevents muscarinic agonist-induced up-regulation of Na(+)/H(+) exchange in mouse parotid acinar cells.

SLC9A2 SLC9A3

2.50e-053101210506152
Pubmed

Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.

ABCC9 ABCA8 ABCC6

4.04e-0523101310708515
Pubmed

Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro.

P2RY2 P2RY4

4.99e-054101212814360
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN3A

4.99e-054101217537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN3A

4.99e-054101235031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN3A

4.99e-054101229578003
Pubmed

Nucleotides downregulate aquaporin 2 via activation of apical P2 receptors.

P2RY2 P2RY4

4.99e-054101219423692
Pubmed

Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population.

HUWE1 SLC1A3

4.99e-054101233581058
Pubmed

Knock-out mice reveal the contributions of P2Y and P2X receptors to nucleotide-induced Ca2+ signaling in macrophages.

P2RY2 P2RY4

4.99e-054101216980298
Pubmed

Cftr and ENaC ion channels mediate NaCl absorption in the mouse submandibular gland.

SLC9A2 SLC9A3

4.99e-054101220026617
Pubmed

A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells.

SLC4A7 SLC4A10

4.99e-054101214592810
Pubmed

TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.

GTF2IRD2B GTF2IRD2

4.99e-054101217823943
Pubmed

Evolution of general transcription factors.

GTF2IRD2B GTF2IRD2

4.99e-054101223229069
Pubmed

P2Y and P2X purinoceptor mediated Ca2+ signalling in glial cell pathology in the central nervous system.

P2RY2 P2RY4

4.99e-054101212151016
Pubmed

GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.

GTF2IRD2B GTF2IRD2

4.99e-054101222899722
Pubmed

NHE1, NHE2, and NHE3 contribute to regulation of intracellular pH in murine duodenal epithelial cells.

SLC9A2 SLC9A3

4.99e-054101210666043
Pubmed

ATM and SIRT6/SNF2H Mediate Transient H2AX Stabilization When DSBs Form by Blocking HUWE1 to Allow Efficient γH2AX Foci Formation.

HUWE1 ATM

4.99e-054101226711340
Pubmed

E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha.

MYCBP2 HUWE1

4.99e-054101220534529
Pubmed

Return to quiescence of mouse neural stem cells by degradation of a proactivation protein.

HUWE1 SLC1A3

4.99e-054101227418510
Pubmed

Na(+)-dependent transporters mediate HCO(3)(-) salvage across the luminal membrane of the main pancreatic duct.

SLC9A2 SLC9A3

4.99e-054101210841524
Pubmed

Contributions of Na+/H+ exchanger isoforms to preimplantation development of the mouse.

SLC9A2 SLC9A3

4.99e-05410129590530
Pubmed

Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.

GTF2IRD2B GTF2IRD2

4.99e-054101221328569
Pubmed

The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis.

HUWE1 ATM

4.99e-054101222213803
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN3A

4.99e-054101235801810
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN3A

4.99e-05410128974318
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

GPR39 TMEM199 HUWE1 PIGU STT3A LRFN4 SLC35B4 FURIN SLC4A10 ATM HERC1 PIGO

6.01e-0510611011233845483
Pubmed

Adoptive cell therapy with tumor-specific Th9 cells induces viral mimicry to eliminate antigen-loss-variant tumor cells.

CXCR5 P2RY2 CCR6

8.22e-0529101334678150
Pubmed

Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons.

SLC4A7 SLC4A10

8.30e-055101223500099
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN3A

8.30e-05510121679748
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN3A

8.30e-05510128812438
Pubmed

A TNF-α-CCL20-CCR6 axis regulates Nod1-induced B cell responses.

CXCR5 CCR6

8.30e-055101224534531
Pubmed

The distinct roles of anion transporters Slc26a3 (DRA) and Slc26a6 (PAT-1) in fluid and electrolyte absorption in the murine small intestine.

SLC9A2 SLC9A3

8.30e-055101224233434
Pubmed

A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange.

SLC9A2 SLC9A3

8.30e-05510128901634
Pubmed

Voltage-Gated Ion Channels Are Transcriptional Targets of Sox10 during Oligodendrocyte Development.

KCNA1 SCN1A

8.30e-055101238995010
Pubmed

Expression pattern of human P2Y receptor subtypes: a quantitative reverse transcription-polymerase chain reaction study.

P2RY2 P2RY4

8.30e-055101211690642
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN3A

8.30e-055101224337656
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

SLC4A7 TMEM199 PTDSS1 PIGU STT3A VANGL1 TRAM2

1.16e-04375101732788342
Pubmed

Molecular transport machinery involved in orchestrating luminal acid-induced duodenal bicarbonate secretion in vivo.

SLC9A2 SLC9A3

1.24e-046101224018950
Pubmed

Early Hearing Loss upon Disruption of Slc4a10 in C57BL/6 Mice.

SLC4A7 SLC4A10

1.24e-046101231001720
Pubmed

Lessons from genetically engineered animal models VIII. Absorption and secretion of ions in the gastrointestinal tract.

SLC9A2 SLC9A3

1.24e-046101210666041
Pubmed

Multiple P2X and P2Y receptor subtypes in mouse J774, spleen and peritoneal macrophages.

P2RY2 P2RY4

1.24e-046101215670583
Pubmed

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.

TRPA1 SCN3A

1.24e-046101223711479
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN3A

1.24e-046101223652591
Pubmed

The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.

SLC4A7 TMEM199 PTDSS1 PIGU VANGL1

1.68e-04176101528692057
Pubmed

Ion channel expression in the developing enteric nervous system.

KCNA1 KCNC4 KCNF1

1.72e-0437101325798587
Pubmed

Expression of astrocyte-related receptors in cortical dysplasia with intractable epilepsy.

P2RY2 P2RY4

1.74e-047101225003238
Pubmed

Expression of P2Y(6) receptors in the developing mouse skeletal muscle and after injury and repair.

P2RY2 P2RY4

1.74e-047101221413988
Pubmed

Calcineurin homologous protein isoform 2 (CHP2), Na+/H+ exchangers-binding protein, is expressed in intestinal epithelium.

SLC9A2 SLC9A3

1.74e-047101212576672
InteractionERMP1 interactions

VIPR2 OR2M7 HTR3A PTDSS1 P2RY2 CCR6 PDCD1LG2

4.29e-06147907int:ERMP1
InteractionSPPL2B interactions

HTR3A SLC35G2 SLC43A3 YTHDC1 PIGU ALG10 CCR6 PIGO

9.71e-06233908int:SPPL2B
InteractionLMBR1 interactions

HTR3A LRFN4 P2RY2 LPAR6 CCR6

2.59e-0578905int:LMBR1
InteractionDHFR2 interactions

HTR3A TMEM199 PTDSS1 DOLPP1 HUWE1 PIGU SLC1A3 HERC1

4.55e-05289908int:DHFR2
Cytoband11q22-q23

SLN ATM

7.01e-056100211q22-q23
GeneFamilySolute carriers

SLC36A1 SLC4A7 SLC35G2 SLC43A3 SLC1A3 SLC9A2 SLC9A3 SLC13A1 SLC24A2 SLC35B4 SLC4A10

8.64e-073957711752
GeneFamilyG protein-coupled receptors, Class A orphans

GPR22 GPR39 GPR135 GPR63 GPR132

2.03e-0578775262
GeneFamilyGlucagon receptor family

GLP2R GHRHR

2.66e-046772269
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN3A

6.32e-0497721203
GeneFamilyPotassium voltage-gated channels

KCNA1 KCNC4 KCNF1

6.55e-0440773274
GeneFamilyPurinergic receptors P2Y

P2RY2 P2RY4

7.88e-0410772213
GeneFamilyBlood group antigens|XK related family

XK XKR3

9.60e-0411772955
GeneFamilyATP binding cassette subfamily C

ABCC9 ABCC6

1.35e-0313772807
GeneFamilyGlycosyl transferases group 1 domain containing|Phosphatidylinositol glycan anchor biosynthesis

PIGU PIGO

3.57e-0321772680
GeneFamilyTaste 2 receptors

TAS2R16 TAS2R45

1.20e-02397721162
CoexpressionAtlascerebral cortex

LRRC63 DOCK4 GPR22 CALHM1 ATCAY SLC1A3 CHRM4 KHDC1 OPRK1 KCNA1 SLC24A2 KCNF1 SCN1A GALNT9 SCN3A SLC4A10 TMEM266 FRMPD3 UNC80 DYNC1I1

1.70e-0614289020cerebral cortex
ToppCellCV-Mild-6|CV / Virus stimulation, Condition and Cluster

LRRC63 ZNF781 LPAR6 CYP4F22 FRMPD3 FITM1

1.90e-06167986cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GPR22 TRPA1 HTR3A ATCAY SCN1A SCN3A

2.83e-06179986af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35G2 KCNC4 SCN1A SLN UNC80 DYNC1I1

2.93e-061809863d54cc767e25d91ed2203d8a03e5bf5e15f21699
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

DOCK4 MYCBP2 ABCC9 ABCA8 CMKLR1 TRAM2

3.32e-0618498667164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR22 SLC35G2 SCN1A SLN UNC80 DYNC1I1

3.32e-061849867d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC9 SLC1A3 BDKRB1 LRFN4 KCNA1 SLC24A2

3.88e-06189986a5306561026e4dfcc39beeb785e5108ac595d136
ToppCellfacs-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC9 SLC1A3 BDKRB1 LRFN4 KCNA1 SLC24A2

3.88e-06189986381058f55908f84375b54601d617389ef43ab855
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC9 SLC1A3 BDKRB1 LRFN4 KCNA1 SLC24A2

3.88e-06189986302b950a6ad578f8aeff7ea6fd15fe631225287d
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A7 MYCBP2 HUWE1 SLC24A2 HERC1 UNC80

4.64e-061959863e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A7 MYCBP2 HUWE1 SLC24A2 HERC1 UNC80

4.64e-061959867796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

MYCBP2 SCN3A SLC4A10 HERC1 UNC80 DYNC1I1

5.36e-0620098648d801219bc771d6c7e151dc88ca4c179988de85
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

SLC36A1 ARHGEF11 CXCR5 P2RY2 HERC1

7.49e-061229851ed865f0ecfe304fb86313ff51c04e9052357270
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|390C / Donor, Lineage, Cell class and subclass (all cells)

IL23A ALG10 TMEM266 ATM FRMPD3

1.62e-05143985d877d914e4e74db2053baa310d318d6440e672bc
ToppCellBAL-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HTR3A KHDC1 CXCR5 SCN3A TRAM2

3.71e-051709857dcb6319ba4d7b258dd0a17449d837800ef46ccc
ToppCellBAL-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HTR3A KHDC1 CXCR5 SCN3A TRAM2

3.71e-051709857377e59fba4bf97ba893ccf6b5e149b5152407be
ToppCellBAL-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HTR3A KHDC1 CXCR5 SCN3A TRAM2

3.71e-05170985e18211029e9ffad54458fd921f455172aad407c7
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR2 GPR135 SLN UNC80 DYNC1I1

4.15e-05174985ecdff386d7f0bc57c170a2c1f4deae5ba7e431b5
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OPRK1 CXCR5 FURIN SLC4A10 CCR6

4.62e-051789850b59e3d75b143bd7bf91a7800a49699c51e68c5a
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|343B / Donor, Lineage, Cell class and subclass (all cells)

SLC36A1 DOLPP1 SLC4A10 CCR6 GPR132

4.62e-051789855289ac61637224ae70ffbc2d164d73116f10af40
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERCC4 GPR63 OPRK1 KCNA1 TRAM2

4.75e-05179985820289f14ecf165758529c236bb220bb1a744f02
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERCC4 GPR63 OPRK1 KCNA1 TRAM2

4.75e-05179985e5f781d35449628a7f356d71e26231dd63482eec
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR2 GPR39 ABCC9 PIGU UTP25

4.75e-05179985e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35G2 SCN1A SLN UNC80 DYNC1I1

4.87e-05180985d76349ecef7c5878bf215e946f032264161eb61b
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK-ILC_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IL23A OPRK1 CXCR5 SLC4A10 CCR6

4.87e-05180985a999a6d219a8e58a8b63802ddf8c95ffaab9cfa0
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR22 SCN1A SLN UNC80 DYNC1I1

4.87e-05180985f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCellBAL-Control-Myeloid-MoAM-MoAM4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DOCK4 SLC36A1 SLC1A3 KCNF1 CMKLR1

5.55e-0518598529d7ddcb9a2e45f76cd5611f7c52b6df689effd3
ToppCellBAL-Control-Myeloid-MoAM-MoAM4-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DOCK4 SLC36A1 SLC1A3 KCNF1 CMKLR1

5.55e-05185985780bdb63ef913a09930063286011c9108381d3a9
ToppCellBAL-Control-Myeloid-MoAM-MoAM4|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DOCK4 SLC36A1 SLC1A3 KCNF1 CMKLR1

5.55e-05185985274b8acccdfe434d14af4cb32fb615c06ec98435
ToppCellBAL-Control-Myeloid-MoAM-MoAM4-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DOCK4 SLC36A1 SLC1A3 KCNF1 CMKLR1

5.55e-05185985b640d9ed6a1e6aa595053065bb992efc0402353e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR22 ST6GALNAC6 KCNC4 TMEM266 UNC80

5.69e-05186985d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR22 HTR3A ATCAY SCN3A DYNC1I1

5.69e-0518698524b23880d4ff8fb4a23e2012d5890b9e2fcf7283
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GPR22 HTR3A ATCAY SCN3A UNC80

5.69e-051869852fdd0a80ad31cf017aafcf5dcf760ebd786b98c1
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNC4 SCN1A SLN FRMPD3 UNC80

5.99e-051889851efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIPR2 ABCC9 ABCA8 GLP2R SLC35B4

6.14e-05189985f7d57723b8fb0f1e1485f51e3eff93ec0f39761e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR22 KCNC4 SCN1A FRMPD3 UNC80

6.14e-05189985f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellCF-Lymphoid-B_cell|CF / Disease state, Lineage and Cell class

SLC4A7 MYCBP2 CXCR5 SCN3A ATM

6.30e-05190985374d8fd63c733178acab07682ed1519693efab45
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYCBP2 GALNT9 SLC4A10 UNC80 DYNC1I1

6.61e-051929854c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellControl-Myeloid-MoAM4|Control / Disease group,lineage and cell class (2021.01.30)

DOCK4 SLC36A1 SLC43A3 SLC1A3 CMKLR1

6.61e-051929851da7c303a2e36af4a9d8ec30a11380d9b1897922
ToppCelldroplet-Lung-nan-21m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR2 SLC35G2 SLC1A3 SCN3A CMKLR1

6.78e-05193985ac4270b26f5dc7ff2220a109e5aae5a113893211
ToppCelldroplet-Lung-nan-21m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR2 SLC35G2 SLC1A3 SCN3A CMKLR1

6.78e-051939857a09739d0b07dcd615cce2da93fd169cc92e566d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR22 KCNC4 SCN1A FRMPD3 UNC80

6.78e-051939855fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR22 CHRM4 KCNF1 SCN3A UNC80

7.12e-05195985ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HTR3A SLC13A1 SLN PDCD1LG2

7.35e-051019846523c314166dcf66c3ed13c02ca4b886b068e5b8
ToppCellnucseq-Immune-Immune_Myeloid-IM|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DOCK4 SLC36A1 SLC1A3 LPAR6 CMKLR1

7.47e-051979856f41c8f815851968849428ec92c16745bd01a3fb
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

DOCK4 SLC1A3 LPAR6 CMKLR1 PDCD1LG2

7.47e-05197985075044c17f1c52008cd3c292c15cbf485b50411e
ToppCellnucseq-Immune-Immune_Myeloid-IM-IM|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DOCK4 SLC36A1 SLC1A3 LPAR6 CMKLR1

7.47e-05197985304044ace926943b8eb588f686ecbe5d1689a809
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN1A SCN3A SLC4A10 UNC80 DYNC1I1

7.65e-05198985c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN1A SCN3A SLC4A10 UNC80 DYNC1I1

7.65e-051989856d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

DOCK4 SLC36A1 GPR22 ABCA8 PIGO

7.65e-051989850c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN1A SCN3A SLC4A10 UNC80 DYNC1I1

7.65e-051989854ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN3A SLC4A10 HERC1 UNC80 DYNC1I1

7.65e-051989850ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellNeuron|World / Primary Cells by Cluster

GPR22 ATCAY SCN3A SLN DYNC1I1

7.83e-051999851f8104fd92f04690b41d9d07ac08dc59d76bb97d
ToppCellNeuron-Postmitotic|World / Primary Cells by Cluster

GPR22 ATCAY SCN3A SLN DYNC1I1

7.83e-051999851973527f8a7d4c6490d75c0d0ea153688166a08b
ToppCellcellseq-Immune-Immune_Myeloid-IM|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLC36A1 SLC1A3 LPAR6 CMKLR1 GPR132

7.83e-05199985b3267d5a7ae0461f5e9e6a3ab6783317a8c42506
ToppCellcellseq-Immune-Immune_Myeloid-IM-IM|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLC36A1 SLC1A3 LPAR6 CMKLR1 GPR132

7.83e-0519998501dacee8bb392639d475be3cb27ba3eeff1e57f1
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MANEA LRFN4 CMKLR1 FRMPD3

2.07e-04132984a1fda8c5287168c4f159203ed27cadfb4ce1b131
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-4|TCGA-Brain / Sample_Type by Project: Shred V9

GPR22 HTR3A GLP2R KCNC4

2.19e-0413498404ee54e788f6659af0349be8c0ff991fcac2b2aa
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sema3c-Inhibitory_Gad1Gad2_Htr3a.Sema3c_(Interneuron,__(candidate_CGE-derived_12))|Hippocampus / BrainAtlas - Mouse McCarroll V32

VIPR2 GPR63 SLN

2.29e-0454983a582a89185bd4c3508a3349e68fca070743e6e75
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sema3c-Inhibitory_Gad1Gad2_Htr3a.Sema3c_(Interneuron,__(candidate_CGE-derived_12))-|Hippocampus / BrainAtlas - Mouse McCarroll V32

VIPR2 GPR63 SLN

2.29e-0454983c593dd57c79c770c7939d641dcfaf6c9c0ff5710
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sema3c|Hippocampus / BrainAtlas - Mouse McCarroll V32

VIPR2 GPR63 SLN

2.29e-0454983b1adbf4632694746511e3051d4306a42223cbb92
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

XK KHDC1 CYP4F22 CMKLR1

2.52e-04139984d96e5c17582f1576fa09d6bad35c418b6248448c
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HTR3A SLC13A1 SLN PDCD1LG2

2.73e-04142984ed91d2ef4c346f7e1a5402846e2a34cee19c24d1
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

HTR3A SLC13A1 SLN TMEM266

2.88e-0414498404f9054895be2275eecda687a6eeb02fa5ec69b9
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Thalamus / BrainAtlas - Mouse McCarroll V32

HTR3A OPRK1 KCNC4 FRMPD3

3.19e-04148984afebb64365c94b9476494bffe7c364677f19c8cf
ToppCellThalamus-Neuronal-Inhibitory|Thalamus / BrainAtlas - Mouse McCarroll V32

HTR3A OPRK1 KCNC4 FRMPD3

3.19e-041489845f82e5ecacfd223020b8ee975c17d68c1fe6db38
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMC4 LHFPL7 P2RY4 CYP4F22

3.28e-04149984dede8ffc14ce63e0058bde1394b31bb4088996b3
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMC4 LHFPL7 P2RY4 CYP4F22

3.28e-0414998497015942c4ac797e1c12a1673cd147c10450b15a
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-Trm_Th1/Th17|bone_marrow / Manually curated celltypes from each tissue

TRPA1 IL23A CCR6 UNC80

3.28e-04149984264fe2ceac6379b3394d2bb47ef34692e4a64559
ToppCellnormal_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

GPR63 CXCR5 LPAR6 ATM

3.28e-04149984a34d095b8e0fe59d69d84e4fd2fe4ccb82f92e4f
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMC4 LHFPL7 P2RY4 CYP4F22

3.36e-0415098465ad642cd237ba0db4bde7371533884db2fa0aae
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC4A7 ABCC9 ATM GPR132

3.36e-041509846c39e73a0b05d4b26589f333ce13924e3d373b8d
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC36A1 GPR22 GPR132 PIGO

3.53e-0415298487a7116d0064a6051bdf28ce1e48bfc168273e66
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Kif5b_(Kif5b)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

LRRC63 CXCR5 P2RY4

3.62e-046398350ea93ea08d8e7a1a2508e8a2c569f6f5dc91961
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Kif5b_(Kif5b)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

LRRC63 CXCR5 P2RY4

3.62e-0463983c30197502348f07ded57ad4e50862e61e2fba51e
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT9 FITM1 GPR132 PDCD1LG2

3.62e-041539840ef7c45cdd854c79e527006034029767f8e108b2
ToppCellBronchial_Biopsy-Epithelial-Goblet_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

GPR22 HTR3A IL23A GPR132

3.62e-04153984e9d6b4e895ddb8d6e6c8b043da591ec11365e124
ToppCellsevere_COVID-19-MAIT|World / disease group, cell group and cell class (v2)

ST6GALNAC6 IL23A SLC4A10 TMEM266

3.71e-0415498465ec7f7ef05c589903c4c9fe3849478c325fdc61
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Kctd12|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC13A1 SLN PDCD1LG2

3.79e-04649832edc3ae3e334bb04a411778e3b102b3a84a97824
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Kctd12-Inhibitory_Gad1Gad2Slc17a8_Htr3a.Ktcd12_(Interneuron,__GABA/Glutamate_co-releasing?_(candidate_CGE-derived_9))-|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC13A1 SLN PDCD1LG2

3.79e-0464983b8aac6e83c2e5b09b55ea22ddb29940099f186e1
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Kctd12-Inhibitory_Gad1Gad2Slc17a8_Htr3a.Ktcd12_(Interneuron,__GABA/Glutamate_co-releasing?_(candidate_CGE-derived_9))|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC13A1 SLN PDCD1LG2

3.79e-04649833e3eed30abcecd3fc8d30489dca05222ac353180
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GALNT9 MCRS1 ATM GPR132

3.81e-04155984b5d5c38b269e9318970fcce564df1c8ed7a7ccc6
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL23A CMKLR1 GPR132 PDCD1LG2

3.90e-0415698439aa3adbee9f04cdc0055487d393edfa515e062b
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL23A CMKLR1 GPR132 PDCD1LG2

3.90e-04156984a09e3aefe78d63ad5428ad48c6f83e547eb819f6
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPA1 WDR81 KCNF1 GALNT9

3.99e-041579841e3a4a7193d95f09d71c2dfe704b8e626c6d9624
ToppCellsevere_COVID-19-MAIT|severe_COVID-19 / disease group, cell group and cell class (v2)

IL23A SLC4A10 TMEM266 CYP4F22

3.99e-04157984175f637e9707836bd63b5c2ccc9d4eb601c05b9e
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC1A3 BDKRB1 LRFN4 CMKLR1

4.09e-041589846d2709b387945c015faa223c20d22b52a4082140
ToppCellICU-NoSEP-Lymphocyte-T_NK-Treg|ICU-NoSEP / Disease, Lineage and Cell Type

SLC4A7 ZNF781 ATCAY TMC4

4.19e-04159984d065ec02a4f3672ba53d4fea66029f1ce68f367f
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR5 SLC13A1 CCR6 PDCD1LG2

4.29e-041609841cb6f42b68c9e41e8edae0de8f0d8371c4620b04
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR22 CXCR5 CCR6 PDCD1LG2

4.29e-041609846bafbe2b4b98bc088406a516d079093f89d9c344
ToppCellfacs-Liver-Liver_non-hepato/SCs|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR5 SLC13A1 CCR6 PDCD1LG2

4.29e-04160984ebefde92db400cbe68d9ce31545a0308e0afbde1
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC35G2 ARHGEF11 SLC9A3 SCN1A

4.39e-04161984b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GPR22 GPR39 KCNF1 GALNT9

4.39e-04161984ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue-6|TCGA-Colorectal / Sample_Type by Project: Shred V9

SLC36A1 ABCA8 GLP2R P2RY4

4.50e-041629847f9385aa749bfb2fa9fee6939fe46d946bc21d31
ToppCellIPF-Epithelial-PNEC|Epithelial / Disease state, Lineage and Cell class

TRPA1 SCN3A UNC80 DYNC1I1

4.50e-04162984865d0e215d54fb1412f00cf0649c71c2f1878e57
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

DOCK4 VIPR2 TMEM266 CMKLR1

4.60e-04163984f1ec2625b52664308968b01d8e0275e1e0751480
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Sncg_(Neuron.Gad1Gad2.Synpr-Sncg)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

HTR3A SLC13A1 SLN

4.73e-04699839778ec48eceef5bd6f59b5b55ca4a6cc348a1eba
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC13A1 SLN PDCD1LG2

4.73e-04699830862e6c8d8af4310b9a1f0879e51ee25115b26b1
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC13A1 SLN PDCD1LG2

4.73e-0469983d2ff9cea216122d697822cdd2eecbce8f557728d
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Sncg_(Neuron.Gad1Gad2.Synpr-Sncg)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

HTR3A SLC13A1 SLN

4.73e-04699838c4c4e2cd4c319adbe44fa2bcb5bb5cd5d81a2fd
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_TNFAIP8L3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRC63 HTR3A OPRK1 SLC13A1

4.82e-04165984cd73bba51f3f4871533c3512bdc0a1f05716344b
ComputationalGenes in the cancer module 146.

HTR3A GPR39 OPRK1 CXCR5 GHRHR OR10H3 LPAR6

9.71e-08102417MODULE_146
ComputationalGenes in the cancer module 289.

GPR39 BDKRB1 OPRK1 CXCR5 GHRHR OR10H3 LPAR6

3.72e-07124417MODULE_289
ComputationalGenes in the cancer module 288.

BDKRB1 OPRK1 CXCR5 CCR6

1.10e-0537414MODULE_288
ComputationalGPCR signaling pathways (immune and neuro).

GPR39 OPRK1 CXCR5 GHRHR LPAR6

2.17e-0590415MODULE_375
ComputationalGenes in the cancer module 27.

HTR3A GPR39 BDKRB1 OPRK1 CXCR5 GHRHR LPAR6

3.44e-04355417MODULE_27
ComputationalGenes in the cancer module 99.

VIPR2 GPR39 SLC1A3 GHRHR KCNA1 KCNC4 CCR6

3.56e-04357417MODULE_99
Drugpotassium

TRPA1 HTR3A ABCC9 XK GRINA IL23A SLC1A3 SLC9A2 SLC9A3 KCNA1 P2RY2 KCNC4 SLC24A2 KCNF1 FURIN SCN3A ALG10

1.31e-0610089817CID000000813
Drug4,4'-diisothiocyanostilbene-2,2'-disulfonic acid

SLC4A7 SLC1A3 SLC9A2 SLC9A3 SLC13A1 P2RY2 P2RY4 LPAR6

3.07e-06206988CID000040600
Drugsodium

SLC36A1 SLC4A7 XK SLC43A3 HUWE1 SLC1A3 SLC9A2 SLC9A3 KCNA1 SLC13A1 P2RY2 KCNC4 SLC24A2 FURIN SCN3A

1.21e-059449815CID000000923
Diseaseepilepsy (implicated_via_orthology)

SLC1A3 BDKRB1 KCNA1 SLC13A1 SCN1A SCN3A

1.59e-05163966DOID:1826 (implicated_via_orthology)
Diseaseoveractive bladder syndrome (implicated_via_orthology)

TRPA1 BDKRB1

3.14e-053962DOID:0070355 (implicated_via_orthology)
DiseaseEpisodic Ataxia

SLC1A3 KCNA1

6.26e-054962C1720189
DiseaseHereditary episodic ataxia

SLC1A3 KCNA1

6.26e-054962cv:C1720189
DiseaseAnhedonia

SLC1A3 OPRK1 CCR6

6.43e-0524963C0178417
Diseasenephrolithiasis (implicated_via_orthology)

SLC9A2 SLC9A3

1.04e-045962DOID:585 (implicated_via_orthology)
DiseaseInherited neuropathies

SLC1A3 KCNA1 ATM

3.02e-0440963C0598589
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN3A

4.63e-0410962DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN3A

4.63e-0410962DOID:0080422 (implicated_via_orthology)
DiseasePain, Migratory

TRPA1 BDKRB1 OPRK1

5.52e-0449963C0751407
DiseaseSuffering, Physical

TRPA1 BDKRB1 OPRK1

5.52e-0449963C0751408
DiseasePain, Crushing

TRPA1 BDKRB1 OPRK1

5.52e-0449963C0458259
DiseasePain, Splitting

TRPA1 BDKRB1 OPRK1

5.52e-0449963C0458257
DiseasePain

TRPA1 BDKRB1 OPRK1

5.52e-0449963C0030193
DiseaseRadiating pain

TRPA1 BDKRB1 OPRK1

5.52e-0449963C0234254
DiseasePain, Burning

TRPA1 BDKRB1 OPRK1

5.52e-0449963C0234230
DiseaseAche

TRPA1 BDKRB1 OPRK1

5.52e-0449963C0234238
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN3A

6.77e-0412962DOID:0060170 (implicated_via_orthology)
DiseasePeripheral Nervous System Diseases

ERCC4 XK DYNC1I1

7.34e-0454963C4721453
Diseasediabetic neuropathy (implicated_via_orthology)

TRPA1 BDKRB1

9.29e-0414962DOID:9743 (implicated_via_orthology)
Diseaseanemia (implicated_via_orthology)

SLC4A7 SLC4A10

1.07e-0315962DOID:2355 (implicated_via_orthology)
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

KCNA1 SCN1A

1.22e-0316962C0393706
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A HERC1

1.55e-0318962HP_0002373
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN3A

2.32e-0322962DOID:2030 (implicated_via_orthology)
DiseaseEpilepsy, Cryptogenic

SLC1A3 SCN1A SLC4A10

2.45e-0382963C0086237
DiseaseAwakening Epilepsy

SLC1A3 SCN1A SLC4A10

2.45e-0382963C0751111
DiseaseAura

SLC1A3 SCN1A SLC4A10

2.45e-0382963C0236018
DiseaseEpilepsy, Benign Psychomotor, Childhood

BDKRB1 KCNC4

2.53e-0323962C0393672
DiseaseEpilepsy, Lateral Temporal

BDKRB1 KCNC4

2.53e-0323962C0393682
DiseaseUncinate Epilepsy

BDKRB1 KCNC4

2.53e-0323962C0014558
DiseaseEpilepsy, Temporal Lobe

BDKRB1 KCNC4

2.53e-0323962C0014556
DiseaseEtat Marbre

XK SCN1A

2.53e-0323962C0266487
DiseaseEdema

SLC9A2 SLC9A3

3.24e-0326962C0013604
DiseaseAnasarca

SLC9A2 SLC9A3

3.24e-0326962C0151603

Protein segments in the cluster

PeptideGeneStartEntry
RVFVFRALLLVLIFL

VANGL1

181

Q8TAA9
RKVTRTIFAILLAFI

CHRM4

396

P08173
LFISIFLVVAISQDR

BDKRB1

121

P46663
KAVRVAILVTSIFFL

CXCR5

256

P32302
LVISLAETIFIVRLV

HTR3A

316

P46098
VLIRSVATDKRAFFI

ARHGEF11

1031

O15085
KAIRVIIAVVLVFLA

CCR6

251

P51684
FVLLTTLLAFVVRSV

CALHM1

191

Q8IU99
FLLSTVVRFAVKAII

ABCC9

586

O60706
IIAFIFIATVIALRK

PDCD1LG2

231

Q9BQ51
RAVVFVIARNAFVSL

OR56A4

146

Q8NGH8
SISYVFIVVAILRIR

OR10V1

216

Q8NGI7
FLAILASYARVLIVV

OR2AK2

226

Q8NG84
TSLAILRVIRLVRVF

KCNA1

286

Q09470
TARRQTIIFLRLIVV

GPR39

276

O43194
SIRQAFIRKVFLVLT

GRINA

156

Q7Z429
FIRKVFLVLTLQLSV

GRINA

161

Q7Z429
VFVIVGFVTLIIFKR

DOLPP1

41

Q86YN1
VFIFVNEALSVILRS

GALNT9

156

Q9HCQ5
FIRTVLAISRPFISV

ATCAY

276

Q86WG3
DFLVFLRRVVSSKAI

HERC1

1906

Q15751
LIFFDRTIRVIERAL

DYNC1I1

231

O14576
VAIIITSYARVILAV

OR2M7

211

Q8NG81
LSRIVIFIEIVGFFI

LPAR6

181

P43657
EFLRIFTIAFNLITV

LRRC63

391

Q05C16
RVYITEVTIFILSIA

OR11L1

191

Q8NGX0
ITFVTRAVRVVDLIT

HUWE1

426

Q7Z6Z7
IIIIIGFLRRDTFTI

NPIPB15

61

A6NHN6
RKSVRTIAVVLAVFA

P2RY2

241

P41231
VLVLVVAVTVRAALF

PIGU

6

Q9H490
RRTCIILALFILFIF

MANEA

6

Q5SRI9
IILSFVFIVAAILRI

OR10H3

216

O60404
ISYFNIVITILRIRS

OR8J2

216

Q8NGG1
LRSLRTIAVVLTVFA

P2RY4

241

P51582
LTIFLKTLAVNFRIR

ATM

236

Q13315
FILRTLAVLVKDVVF

GLP2R

221

O95838
LRFFSEVRTATTVLI

GPR135

321

Q8IZ08
ALESIFKFIVRSRIL

DOCK1

741

Q14185
DFLLQIFTVFRILIR

DOCK4

946

Q8N1I0
FVLLVVFLATRRVAV

FITM1

106

A5D6W6
FQVLSSLIETFVRLV

FRMPD3

1696

Q5JV73
SLIETFVRLVFIVRS

FRMPD3

1701

Q5JV73
VLVFVTVFLVLQLRS

FURIN

726

P09958
FRNAFVLLTVTAVIV

SLC1A3

46

P43003
LRFKILRSLQAFVAV

IL23A

161

Q9NPF7
IVALFVAITILVALR

GHRHR

141

Q02643
SVVEIASLRFVFLIN

MCRS1

431

Q96EZ8
QRLFRVLFVIETVSE

KHDC1

6

Q4VXA5
RAFTTILILFAVFIV

GPR63

311

Q9BZJ6
RRILEAAEFIKFTVI

GTF2IRD2

391

Q86UP8
RRILEAAEFIKFTVI

GTF2IRD2B

391

Q6EKJ0
VFGVRTSVSVIIALR

GPR22

281

Q99680
RTIIFSSATERIIFV

LHFPL7

181

Q6ICI0
RRFLFVVFTVLVLLP

SLC13A1

11

Q9BZW2
RVVVALTLLRFRLSV

CYP4F22

486

Q6NT55
RITRLVLVVVAVFVV

OPRK1

271

P41145
RRTAILISACIFILV

GPR132

156

Q9UNW8
ARFTALRSLAVLFIV

TAS2R16

221

Q9NYV7
KVLQTVISFFLLRAI

TAS2R45

226

P59539
FREAALRVVQLFISL

UTP25

361

Q68CQ4
RSTISDFAVFLTIVI

SLC4A7

856

Q9Y6M7
LVVTLRKFVSLIFSI

SLC35B4

271

Q969S0
AVIFVFRLASNILRK

SMIM34

61

A8MWV9
YLRSVLAVIAFITLV

TMEM150A

176

Q86TG1
FVFLVVSVLLEDRIL

SLC24A2

641

Q9UI40
LVQARVSFDRLVTFL

ABCC6

591

O95255
LIFIRSVFQVLSVLV

SLC35G2

136

Q8TBE7
VLLTLVFISVYRAIG

SLC9A3

371

P48764
EVLFRSVISLVGFVL

STT3A

296

P46977
QRSAVFVILFALITI

ST6GALNAC6

41

Q969X2
IFDRFKTTVARLIAI

SLC43A3

91

Q8NBI5
AETLRVFRLITSQVF

MYCBP2

3896

O75592
LVLSRINLVFIVLFT

SCN3A

1556

Q9NY46
RELFLNFTIVLITVI

SLN

6

O00631
TILSRINLVFIVLFT

SCN1A

1571

P35498
ALFLALVIRSTQFII

ABCA8

281

O94911
KRRILFFVVTLVSVF

ALG10

321

Q5BKT4
ARVTRIFLVVVYSIV

CMKLR1

36

Q99788
VRIFVIIFLVILSVF

TMEM92

56

Q6UXU6
TRFFLLAIELSVIIL

TPRA1

121

Q86W33
RSLKALVITIFNFIV

TMEM199

141

Q8N511
ILKTLLRSTVVFIFL

TRPA1

866

O75762
FLDFIVRTRIPIFVL

UNC80

2836

Q8N2C7
LAVFSRVKFTRVLLT

NAA35

231

Q5VZE5
RVKFTRVLLTVLIAF

NAA35

236

Q5VZE5
VLLVFIRNLRALSIF

SLC36A1

206

Q7Z2H8
VVIFFTVFILGITIR

SLC9A2

466

Q9UBY0
VFGVTRLFILTLAVL

TRAM2

251

Q15035
TRSRQIVFILLRTVF

TMC4

421

Q7Z404
IVFILLRTVFLRLAS

TMC4

426

Q7Z404
VRSIVSDFAVFLTIL

SLC4A10

756

Q6U841
ISVLVIIFILRGTRA

TRAV16

6

A0A0A6YYK6
FRSARSVILIFSVRE

YTHDC1

391

Q96MU7
SIIVNFVLFISIIRI

VIPR2

291

P41587
VISRVVTLAFFIASL

XKR3

246

Q5GH77
RFSRVVLVLIDALRF

PIGO

66

Q8TEQ8
VIFATSRILVVDFLT

ERCC4

106

Q92889
RGILSVIFFFLIISV

PTDSS1

71

P48651
IAQLLFSIREFTLVR

ZNF781

156

Q8N8C0
SFEIATRVVVLVLFT

XK

216

P51811
SQAKVLFILFRVLRA

WDR81

256

Q562E7
LSVFFSETVLRIVVL

TMEM266

146

Q2M3C6
RVVAFASLFFILVSI

KCNC4

226

Q03721
ARVVAVLSFLLILVS

KCNF1

181

Q9H3M0
LVAALLVFTVALLVR

LRFN4

526

Q6PJG9