Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabnormal pleura morphology

LAMA5 ELK3

2.69e-052732MP:0010820
DomainTox-GHH_dom

TENM3 TENM1 TENM2

4.61e-074923IPR028916
DomainTen_N

TENM3 TENM1 TENM2

4.61e-074923IPR009471
DomainTen_N

TENM3 TENM1 TENM2

4.61e-074923PF06484
DomainTENEURIN_N

TENM3 TENM1 TENM2

4.61e-074923PS51361
DomainTox-GHH

TENM3 TENM1 TENM2

4.61e-074923PF15636
DomainYD

TENM3 TENM1 TENM2

1.15e-065923IPR006530
DomainEGF-like_dom

FRAS1 TENM3 PCSK6 TENM1 LAMA5 LTBP2 C6 TENM2

3.16e-05249928IPR000742
DomainNHL

TENM3 TENM1 TENM2

3.19e-0513923PS51125
DomainRhs_assc_core

TENM3 TENM2

7.18e-053922IPR022385
DomainEGF

FRAS1 TENM3 PCSK6 TENM1 LAMA5 LTBP2 TENM2

1.61e-04235927SM00181
Domain-

SND1 TDRD6

3.55e-0469222.40.50.90
DomainEPTP

TSPEAR ADGRV1

3.55e-046922PF03736
DomainStaphylococal_nuclease_OB-fold

SND1 TDRD6

3.55e-046922IPR016071
DomainEPTP

TSPEAR ADGRV1

3.55e-046922IPR005492
DomainEAR

TSPEAR ADGRV1

4.96e-047922IPR009039
DomainEAR

TSPEAR ADGRV1

4.96e-047922PS50912
DomainCalx_beta

FRAS1 ADGRV1

6.59e-048922SM00237
DomainCalx_beta

FRAS1 ADGRV1

8.45e-049922IPR003644
DomainCalx-beta

FRAS1 ADGRV1

8.45e-049922PF03160
Domain-

TENM3 TENM1 TENM2

9.30e-04399232.120.10.30
Domain6-blade_b-propeller_TolB-like

TENM3 TENM1 TENM2

1.51e-0346923IPR011042
DomainEGF_1

TENM3 TENM1 LAMA5 LTBP2 C6 TENM2

1.64e-03255926PS00022
DomainEGF-like_CS

TENM3 TENM1 LAMA5 LTBP2 C6 TENM2

1.84e-03261926IPR013032
DomainEGF_2

TENM3 TENM1 LAMA5 LTBP2 C6 TENM2

1.99e-03265926PS01186
DomainTUDOR

SND1 TDRD6

2.10e-0314922PF00567
DomainPropept_inh

CPA5 PCSK6

3.11e-0317922IPR009020
DomainCarboxyPept-like_regulatory

TENM3 TENM2

3.11e-0317922IPR008969
DomainEGF_extracell

TENM3 TENM1 LTBP2

3.23e-0360923IPR013111
DomainEGF_2

TENM3 TENM1 LTBP2

3.23e-0360923PF07974
DomainFurin_repeat

FRAS1 PCSK6

3.49e-0318922IPR006212
DomainFU

FRAS1 PCSK6

3.49e-0318922SM00261
DomainTUDOR

SND1 TDRD6

5.68e-0323922PS50304
DomainEGF_3

TENM3 TENM1 LTBP2 C6 TENM2

6.12e-03235925PS50026
DomainGrowth_fac_rcpt_

FRAS1 PCSK6 LAMA5 LTBP2

7.41e-03156924IPR009030
DomainHECT

HUWE1 HECTD1

7.78e-0327922PF00632
DomainHECTc

HUWE1 HECTD1

7.78e-0327922SM00119
DomainTUDOR

SND1 TDRD6

7.78e-0327922SM00333
DomainHECT_dom

HUWE1 HECTD1

7.78e-0327922IPR000569
DomainHECT

HUWE1 HECTD1

7.78e-0327922PS50237
DomainETS_DOMAIN_1

ELK3 ELK4

8.35e-0328922PS00345
DomainETS_DOMAIN_2

ELK3 ELK4

8.35e-0328922PS00346
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CCNE1 FRAS1 SND1 SZT2 UBR4 PEX6 LAMA5 DISP2 TMCO6 PANX1 GPC2 HUWE1 RALGAPA2 HECTD1 TRAPPC9 ACOX3 NBPF1

5.39e-091105931735748872
Pubmed

Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.

TENM3 TENM1 TENM2

7.39e-08493310225957
Pubmed

All four members of the Ten-m/Odz family of transmembrane proteins form dimers.

TENM3 TENM1 TENM2

7.39e-08493312000766
Pubmed

The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.

TENM3 TENM1 TENM2

6.43e-07793312915301
Pubmed

Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.

TENM3 TENM1 TENM2

1.03e-06893310331952
Pubmed

Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.

TENM3 TENM1 TENM2

2.19e-061093338713721
Pubmed

hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ.

BRIP1 MSH5

7.07e-06293226055704
Pubmed

Mapping of the human SAP1 (SRF accessory protein 1) gene and SAP2, a gene encoding a related protein, to chromosomal bands 1q32 and 12q23, respectively.

ELK3 ELK4

7.07e-0629327851904
Pubmed

Regulation of human cystic fibrosis transmembrane conductance regulator (CFTR) by serum- and glucocorticoid-inducible kinase (SGK1).

SGK1 CFTR

7.07e-06293217595519
Pubmed

Serum and glucocorticoid-inducible kinase1 increases plasma membrane wt-CFTR in human airway epithelial cells by inhibiting its endocytic retrieval.

SGK1 CFTR

7.07e-06293224586903
Pubmed

Gender differences in genetic risk profiles for cardiovascular disease.

ITGA2 USF1 F2R CRP

7.17e-064693418974842
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FRAS1 TENM3 WDR7 DNAJC16 PEG3 DISP2 CSMD3 TENM2

1.41e-0540793812693553
Pubmed

PEG3 control on the mammalian MSL complex.

HOXB9 PEG3 ASCC3

1.47e-051893328609438
Pubmed

An integrated genetic map of the pearl locus of mouse chromosome 13.

RASA1 ITGA2 F2R

1.74e-05199338828042
Pubmed

Elk3 deficiency causes transient impairment in post-natal retinal vascular development and formation of tortuous arteries in adult murine retinae.

ELK3 ELK4

2.12e-05393225203538
Pubmed

Adhesion regulates MAP kinase/ternary complex factor exchange to control a proliferative transcriptional switch.

ELK3 ELK4

2.12e-05393223063436
Pubmed

Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway.

ELK3 ELK4

2.12e-0539329644975
Pubmed

Ternary complex factors SAP-1 and Elk-1, but not net, are functionally equivalent in thymocyte development.

ELK3 ELK4

2.12e-05393220554967
Pubmed

Alpha2(VIII) collagen substrata enhance endothelial cell retention under acute shear stress flow via an alpha2beta1 integrin-dependent mechanism: an in vitro and in vivo study.

COL8A2 ITGA2

2.12e-05393216908762
Pubmed

Net, a new ets transcription factor that is activated by Ras.

ELK3 ELK4

2.12e-0539327958835
Pubmed

Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.

LAMA5 MFSD4B CSMD3 TRAPPC9

2.53e-056393411572484
Pubmed

Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.

TENM3 TENM1 CSMD3

2.75e-052293335245678
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

APH1B PTPRB RASA1 UACA ENTPD1 ANKMY1 ELK3 ELK4 MSH5 ADGRV1 HUWE1 HECTD1 TRAPPC9 NBPF1

4.09e-051489931428611215
Pubmed

Locations of the ets subfamily members net, elk1, and sap1 (ELK3, ELK1, and ELK4) on three homologous regions of the mouse and human genomes.

ELK3 ELK4

4.23e-0549328575773
Pubmed

Suboptimal activation of protease-activated receptors enhances alpha2beta1 integrin-mediated platelet adhesion to collagen.

ITGA2 F2R

4.23e-05493219815553
Pubmed

The ETS-domain transcription factor family.

ELK3 ELK4

4.23e-0549329570133
Pubmed

TRIM26 promotes non-small cell lung cancer survival by inducing PBX1 degradation.

UBR4 HUWE1

4.23e-05493237324936
Pubmed

Identification of the intermediate filament protein synemin/SYNM as a target of myocardin family coactivators.

ELK3 ELK4

4.23e-05493231461342
Pubmed

Structure and localization of the thrombin receptor gene on mouse chromosome 13.

RASA1 F2R

4.23e-0549328678993
Pubmed

Neuroinflammation-Induced Interactions between Protease-Activated Receptor 1 and Proprotein Convertases in HIV-Associated Neurocognitive Disorder.

PCSK6 F2R

4.23e-05493226283733
Pubmed

A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability.

ENTPD1 PANX1

4.23e-05493233653920
Pubmed

Activation of 3-phosphoinositide-dependent kinase 1 (PDK1) and serum- and glucocorticoid-induced protein kinase 1 (SGK1) by short-chain sphingolipid C4-ceramide rescues the trafficking defect of ΔF508-cystic fibrosis transmembrane conductance regulator (ΔF508-CFTR).

SGK1 CFTR

4.23e-05493225384981
Pubmed

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.

FAH CAD WDR7 UBR4 HUWE1

4.26e-0514393530397336
Pubmed

Rescue of DeltaF508-CFTR by the SGK1/Nedd4-2 signaling pathway.

SGK1 CFTR

7.04e-05593219617352
Pubmed

Activity-Based Probes for HECT E3 Ubiquitin Ligases.

HUWE1 HECTD1

7.04e-05593228425671
Pubmed

The expression of ELK transcription factors in adult DRG: Novel isoforms, antisense transcripts and upregulation by nerve damage.

ELK3 ELK4

7.04e-05593220304071
Pubmed

Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET).

ELK3 ELK4

7.04e-0559327540136
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

FRAS1 TENM3 WFS1 DNAJC16 TMEM161B RNFT1 KIAA1549 LAMA5 TMEM131L LTBP2 ITGA2 HECTD1

8.62e-051201931235696571
Pubmed

The thrombospondin-4 gene.

RASA1 ITGA2

1.05e-04693210501972
Pubmed

A common protein interaction domain links two recently identified epilepsy genes.

TSPEAR ADGRV1

1.05e-04693212095917
Pubmed

The novel EPTP repeat defines a superfamily of proteins implicated in epileptic disorders.

TSPEAR ADGRV1

1.05e-04693212217514
Pubmed

Platelet gene polymorphisms and risk of bleeding in patients undergoing elective coronary angiography: a genetic substudy of the PRAGUE-8 trial.

ITGA2 F2R

1.05e-04693220691446
Pubmed

Id helix-loop-helix proteins inhibit nucleoprotein complex formation by the TCF ETS-domain transcription factors.

ELK3 ELK4

1.05e-04693210022839
Pubmed

Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).

TENM3 TENM1 TRAPPC9

1.46e-043893322952603
Pubmed

Whirlin replacement restores the formation of the USH2 protein complex in whirlin knockout photoreceptors.

ADGRV1 RHO

1.47e-04793221212183
Pubmed

The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.

TENM3 TENM2

1.47e-04793210625539
Pubmed

Localization of extracellular matrix receptors in ICGN mice, a strain of mice with hereditary nephrotic syndrome.

ITGA2 RHO

1.47e-04793211767049
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

FRAS1 PCSK6 LAMA5 HECTD1

1.54e-0410093425807483
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

UACA KIAA1549 HUWE1 SEMA4G

1.60e-0410193410997877
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

FRAS1 CAD UACA SND1 WFS1 DNAJC16 UBR4 KIAA1549 TMEM131L PNPLA8 ASCC3 DNA2 FTSJ3

1.63e-041487931333957083
Pubmed

Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice.

FRAS1 LAMA5

1.96e-04893212766770
Pubmed

HIC1 deletion promotes breast cancer progression by activating tumor cell/fibroblast crosstalk.

ROBO3 F2R

2.52e-04993230204129
Pubmed

Basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome.

FRAS1 LAMA5

3.14e-041093215623520
Pubmed

Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain.

UBR4 HUWE1 HECTD1

3.31e-045093317550899
Pubmed

Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.

TENM3 TENM1 TENM2

3.51e-045193316919471
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

CCNE1 WFS1 DNAJC16 MRGPRF UBR4 RNFT1 F2R

3.93e-0449993722810586
Pubmed

Alpha9 and beta8 integrin expression correlates with the merger of the developing mouse eyelids.

LAMA5 ITGA2

4.59e-041293210090148
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

FRAS1 CAD CPA5 TENM1 CSMD3 HECTD1 NBPF1

4.63e-0451393725798074
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

FRAS1 SND1 WFS1 DNAJC16 TMEM131L ASCC3

5.23e-0437593632788342
Pubmed

The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.

UBR4 HUWE1

6.30e-041493227626314
Pubmed

MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism.

BRIP1 DNA2

7.26e-041593222678361
Pubmed

Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.

UBR4 HUWE1 HECTD1

7.50e-046693324811749
Pubmed

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.

CAD UACA SND1 ASCC3 FTSJ3

7.83e-0426893533024031
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

OR8H2 C5orf22 UACA PCSK6 KIAA1549 PEX6 ASCC3 RALGAPA2 DNA2 FTSJ3

8.08e-041116931031753913
Pubmed

Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma.

CCNE1 FBXW2

8.28e-041693222388891
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

UACA DNAJC16 CFTR KIAA1549 PANX1 ITGA2 RALGAPA2

8.52e-0456993730639242
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

APH1B TMEM131L PNPLA8 GPC2 ADGRV1 ASCC3 USF1 RHO

9.17e-0475093811230166
Pubmed

Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality.

SZT2 DNAJC16 TMEM131L

9.27e-047193336305789
Pubmed

Olfactory receptors and signalling elements in the Grueneberg ganglion.

OR8H2 OR8H3

9.37e-041793216805845
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

YIF1A UACA SND1 PCSK6 ASCC3 DNA2 HECTD1 FTSJ3

9.48e-0475493833060197
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

YIF1A SND1 WFS1 DNAJC16 PCSK6 UBR4 HUWE1 ASCC3 HECTD1

9.53e-0494293931073040
Pubmed

Endothelial Cyp26b1 restrains murine heart valve growth during development.

PTPRB ENTPD1 ELK3 F2R

9.82e-0416393435364055
Pubmed

SARS-CoV-2 ORF8 Protein Induces Endoplasmic Reticulum Stress-like Responses and Facilitates Virus Replication by Triggering Calnexin: an Unbiased Study.

CAD UBR4

1.05e-031893236877072
Pubmed

Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis.

LAMA5 ITGA2

1.05e-031893219686679
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

FRAS1 LAMA5

1.05e-031893214730302
Pubmed

Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease.

TENM3 TENM1

1.05e-031893224058526
Pubmed

Functional proteomics mapping of a human signaling pathway.

TENM3 UBR4 PEX6 LAMA5 HUWE1 ASCC3 ACOX3

1.06e-0359193715231748
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

CLDN11 WFS1 CFTR KIAA1549 PNPLA8 ADGRV1

1.06e-0343093632581705
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

SGK1 UBR4 HUWE1 NBPF1

1.15e-0317093423314748
Pubmed

Autoregulation of the 26S proteasome by in situ ubiquitination.

UBR4 HUWE1

1.17e-031993224743594
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

CAD SND1 HUWE1 ASCC3 HECTD1 FTSJ3

1.20e-0344093634244565
Pubmed

The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.

WFS1 DNAJC16 PANX1 ITGA2

1.30e-0317693428692057
Pubmed

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

CAD UACA UBR4 HUWE1

1.47e-0318293431067453
Pubmed

Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.

CAD UBR4 HUWE1

1.51e-038493329563501
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

SND1 DNAJC16 ECHDC1 ASCC3 DNA2 TENM2

1.53e-0346293631138677
Pubmed

Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.

MYLIP FBXW2 HUWE1

1.56e-038593319028597
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

YIF1A WFS1 DNAJC16 TMEM131L PANX1 ITGA2

1.63e-0346893631056421
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

CAD SND1 DNAJC16 UBR4 HUWE1 ASCC3 HECTD1

1.64e-0363893733239621
Pubmed

A global genomic transcriptional code associated with CNS-expressed genes.

CCNE1 TENM3 SGK1 ITGA2 SEMA4G

1.67e-0331893516919269
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CAD SND1 UBR4 HUWE1 ASCC3 HECTD1 FTSJ3

1.87e-0365393722586326
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

UBR4 PEG3 LAMA5 HUWE1 ASCC3 HECTD1

1.88e-0348193628190767
Pubmed

Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses.

XYLT1 CSMD3

1.88e-032493218755693
Pubmed

ETS-dependent regulation of a distal Gata4 cardiac enhancer.

ELK3 ELK4

1.88e-032493222056786
Pubmed

UPF2 is a critical regulator of liver development, function and regeneration.

ADHFE1 TMEM161B

1.88e-032493220657840
Pubmed

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.

TENM3 TENM1 TENM2

1.90e-039193328558017
Pubmed

Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.

SGK1 TENM1 TENM2

1.90e-039193322610502
Pubmed

ZFP57 dictates allelic expression switch of target imprinted genes.

PEG3 TRAPPC9

2.04e-032593233500348
Pubmed

The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map.

TENM3 ELK3 TENM2

2.08e-039493323431145
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

UBR4 HUWE1 HECTD1

2.14e-039593329643511
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

CAD UACA ASCC3 HECTD1

2.16e-0320293433005030
CoexpressionGSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_UP

XYLT1 SGK1 TNFSF8 MYLIP TENM1 TMEM131L PNPLA8

5.41e-06195917M4195
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 MRGPRF MFSD6 TSPEAR F2R TENM2

2.37e-06183936612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

XYLT1 FRAS1 PEG3 KIAA1549 RALGAPA2 SEMA4G

2.52e-06185936636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLDN11 UACA MRGPRF MFSD6 F2R TENM2

2.69e-0618793624c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLDN11 UACA MRGPRF MFSD6 F2R TENM2

3.13e-06192936ef0aba777072429a6ab7dcfcc305673975946580
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLDN11 UACA MRGPRF MFSD6 F2R TENM2

3.22e-061939363eaa0461618582a1754400624350d269d24e750a
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

XYLT1 PTPRB UACA ENTPD1 ITGA2 RALGAPA2

3.22e-06193936e1d546165dcc2392f540162206852c4717d7306f
ToppCellfacs-Liver-Non-hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN11 PTPRB SGK1 MYLIP ELK3 F2R

3.22e-061939368084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAD WFS1 UBR4 PEG3 DISP2 HUWE1

3.32e-061949360b023de48ed8a550d169bbe954881eb04bf4f981
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTPRB UACA SGK1 PEG3 ELK3 ITGA2

3.32e-0619493644c7d4b75f3b7c9301eba20610e548a01a84ae40
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTPRB UACA SGK1 PEG3 ELK3 ITGA2

3.32e-061949367f24023df47935286f185dd428d48797daf26f49
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM3 WDR7 WFS1 PEG3 DISP2 TENM2

3.42e-06195936bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 MYLIP ELK3 RALGAPA2 F2R

3.63e-06197936deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 MYLIP ELK3 RALGAPA2 F2R

3.63e-06197936a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 MYLIP ELK3 RALGAPA2 F2R

3.73e-06198936f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRB UACA SGK1 ENTPD1 ELK3 ITGA2

3.96e-06200936392abf38afc874925618397ae320a630e18b8e0a
ToppCellLPS_only-Endothelial-Endothelial-Vein|LPS_only / Treatment groups by lineage, cell group, cell type

PTPRB ENTPD1 SLC25A47 ELK3 RALGAPA2 F2R

3.96e-06200936b036f5e22c95a3b14391785b6e91aa183b9bc9a8
ToppCellPND01-Immune-Immune_Myeloid-DC-cDC2|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNE1 HLA-DMB SZT2 TNFSF8 DNA2

1.69e-05152935cefc0ab592e99badf145fb95adf9906cb81be81c
ToppCellPND01-Immune-Immune_Myeloid-DC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNE1 HLA-DMB SZT2 TNFSF8 DNA2

1.69e-05152935c8faa83dcaddb2ce2bb890f90dd8e676f7dcb1b3
ToppCellPND01-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNE1 HLA-DMB SZT2 TNFSF8 DNA2

1.69e-05152935c3f00beb8b6fde99263d5ed6bbe3c2415d02f91d
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Matrix_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

CLDN11 PTPRB SGK1 ELK3 MFSD4B

1.79e-05154935928f49839b046b90c2f942458f3e365ddc4e0bc9
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C5orf22 TNFSF8 PEG3 TENM2 SBK2

1.97e-051579351f21d78a467fe22c5ab75d0917b840c1ac93f32c
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADHFE1 CFTR LAMA5 DISP2 C6

2.43e-05164935fe11fcce4ba7f44ba2989ea3705916b67e75f8e7
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADHFE1 CFTR LAMA5 DISP2 C6

2.43e-05164935b6beb8548ac0dd07e8a580a938e5ee4bf25a3c1f
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 LTBP2 C6 ADGRV1 CSMD3

2.80e-0516993512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellnormal_Lung-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

BRIP1 TNFSF8 ITGA2 DNA2 ACOX3

3.22e-05174935e324320b52c904496e26fcecfa179b3431729ec0
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAH FRAS1 HLA-DMB ADGRV1 CSMD3

3.31e-05175935887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

PTPRB PCSK6 TSPEAR ELK3 RALGAPA2

3.40e-0517693598c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

PTPRB PCSK6 TSPEAR ELK3 RALGAPA2

3.40e-05176935c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellfacs-Lung-EPCAM-18m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 LAMA5 ELK3 SBK2

3.50e-051779352433924dcb085ebbe2545d476ebd7ee68e6092fb
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

PTPRB TENM3 PCSK6 TSPEAR ELK3

3.59e-05178935c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRB WFS1 TSPEAR ELK3 RALGAPA2

3.69e-05179935abc6797bd3884aa75dca58fcb2523ee321243ab1
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRB WFS1 TSPEAR ELK3 RALGAPA2

3.69e-051799350b996d6e881f31e6b80d359f7caac70ecdeb9982
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

UACA PCSK6 CFTR ITGA2 ADGRV1

3.79e-0518093512f3c4c4aa7fe03c0ef847bd4d4942c808015f5f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

UACA PCSK6 CFTR ITGA2 ADGRV1

3.79e-051809351bc01bb76d0d3f8db74f9244436d3e6d6015ed5d
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

UACA PCSK6 CFTR ITGA2 ADGRV1

3.79e-051809352a28fbfe10a340c8662c2c8be33792f41fc09088
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB MYLIP DISP2 ELK3 F2R

3.89e-051819354df7972f88117108698efd06b124b232f8588981
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB MYLIP DISP2 ELK3 F2R

3.89e-05181935cbb530566893281289026bfd93adf721decd4ca3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLDN11 UACA MRGPRF F2R TENM2

3.99e-05182935cde8fa4f42d25545abaa9ee885b4b1e24a5a8e08
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UACA WFS1 TSPEAR ELK3 RALGAPA2

4.10e-05183935764ea07621f77fbd13a877aed5806ae2b3dfb43e
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UACA WFS1 TSPEAR ELK3 RALGAPA2

4.10e-0518393538a54216458ad57f356bb4ddf272e1af8036ddeb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 MRGPRF TSPEAR F2R TENM2

4.10e-051839357c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 CFTR TENM1 ADGRV1 CSMD3

4.21e-051849352cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 CFTR TENM1 ADGRV1 CSMD3

4.21e-05184935ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 CFTR TENM1 ADGRV1 CSMD3

4.21e-051849352b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellnormal-na-Lymphocytic-lymphocyte-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

XYLT1 BRIP1 SLF2 ELK3 GPC2

4.21e-051849352c286712428662bc4589dc5ac4011bf7ed403cb5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 UACA MRGPRF TSPEAR TENM2

4.32e-051859359197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

PTPRB PCSK6 TSPEAR ELK3 RALGAPA2

4.32e-051859354a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 UACA MRGPRF TSPEAR TENM2

4.32e-05185935ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 UACA MRGPRF TSPEAR TENM2

4.32e-05185935b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

PTPRB PCSK6 TSPEAR ELK3 RALGAPA2

4.32e-0518593536ce23893915f5c380cca39b2c33a516edf31c3a
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB MYLIP LAMA5 ELK3 ITGA2

4.32e-05185935bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLDN11 UACA MRGPRF F2R TENM2

4.43e-051869351094c7140131454b2583200e1c01e81ccab3db23
ToppCelldroplet-Heart-nan-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXB9 PTPRB UACA SGK1 MYLIP

4.43e-0518693549ad01d216860a2bd4d63905a7064471b02f2b37
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

BRIP1 TMEM161B TMEM131L HUWE1 DNA2

4.43e-051869358571956890fc9894d766ba294a28e376b4aba428
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 ENTPD1 ELK3 F2R

4.54e-05187935f2a0d0829dc88aa93bfb2eebbbc0ef156a9cba84
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRB UACA ENTPD1 ELK3 ITGA2

4.54e-051879350ef82111b9049cc7ee78d64d240e1f10ab14d6b6
ToppCellfacs-Aorta-Heart-3m-Endothelial-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB UACA SGK1 ENTPD1 ELK3

4.54e-05187935df0279b7e94e26f5541b0e2a0ce56befa96ec8ca
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 ENTPD1 ELK3 F2R

4.54e-05187935fa71f9220b288ed6a1d06f347fec42649aac1f13
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLDN11 UACA MRGPRF F2R TENM2

4.66e-051889359db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM3 HLA-DMB PEG3 DISP2 TENM2

4.66e-05188935a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLDN11 UACA MRGPRF F2R TENM2

4.66e-05188935047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRB TENM3 UACA OSBPL7 ELK3

4.78e-05189935e60a3d6aa84788c29f23439f1c747431ea581bc3
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 ENTPD1 ELK3 F2R

4.78e-0518993592319bef1f00d6048ba8f9f8b5c6dbb896686b74
ToppCellfacs-Thymus-Epithelium-24m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN11 PCSK6 PEG3 DISP2 TENM2

5.02e-05191935eec14997d2bfc7e6b5a601afc43a147f6b96d668
ToppCellfacs-SCAT-Fat-3m-Endothelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB UACA SGK1 LAMA5 ELK3

5.02e-05191935a0018f88f7132477cc467ee15db029a585290595
ToppCellfacs-Thymus-Epithelium-24m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN11 PCSK6 PEG3 DISP2 TENM2

5.02e-051919351730ec5dc1cfd2f0cba7e21555641c7bce97e09d
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

WDR7 TMEM161B TMEM131L HUWE1 DNA2

5.02e-051919359454f642c3621370fa23640b631301346b300950
ToppCellfacs-SCAT-Fat-3m-Endothelial-endothelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB UACA SGK1 LAMA5 ELK3

5.02e-051919356b9bbf4a63d4e9a8075bb06c2aa644fcf4ee88b8
ToppCellfacs-Thymus-Epithelium-24m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN11 PCSK6 PEG3 DISP2 TENM2

5.02e-051919354b77abc68bd72c64e7062f9527fe9d9605289ceb
ToppCellfacs-SCAT-Fat-3m-Endothelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB UACA SGK1 LAMA5 ELK3

5.02e-0519193590f0c193dce267a4f1a9b2501f636dafd0a34cf7
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FRAS1 TENM3 UACA LTBP2 ITGA2

5.02e-051919356688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRB ENTPD1 ELK3 RALGAPA2 F2R

5.15e-051929351ee4783051ec94ea94600f040edcb385fc4289f1
ToppCellLPS_only-Endothelial-Endothelial-Vein|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLDN11 PTPRB ENTPD1 C6 F2R

5.15e-0519293552acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 MYLIP ELK3 RALGAPA2

5.15e-051929352bfac6b3956265205ca47d06888851ed68b65999
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FRAS1 TENM3 UACA LTBP2 ITGA2

5.15e-0519293599ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRB WFS1 TSPEAR ELK3 RALGAPA2

5.15e-051929354e63d95f75fe6eb3f817e84528883e95093c5bbd
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 ELK3 TDRD6 F2R

5.15e-051929355890076929598e88fe9d59a4e4e858b446746ce9
ToppCellLPS-IL1RA-Endothelial-Endothelial-Vein|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLDN11 PTPRB ENTPD1 C6 F2R

5.15e-05192935717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 MYLIP ELK3 RALGAPA2

5.15e-05192935d525f7f088a53110912600a7c9f6d33b9270d534
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

FRAS1 TENM3 UACA LTBP2 ITGA2

5.15e-0519293562904f94dfce430456f05066522cbf9bd29f4d7e
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 ELK3 TDRD6 F2R

5.28e-051939354a8c97ff2dffc5c06351d1cb107e21e58250aa55
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAD WFS1 UBR4 PEG3 DISP2

5.28e-05193935471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 ELK3 TDRD6 F2R

5.28e-05193935d5f6d6e2c36d4e80af4d39cdfc0b18df295a587b
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

TENM3 UACA LTBP2 ITGA2 TENM2

5.28e-05193935ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAD WFS1 UBR4 PEG3 DISP2

5.28e-05193935fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLDN11 PTPRB ENTPD1 C6 F2R

5.28e-051939357261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAD WFS1 UBR4 PEG3 DISP2

5.41e-051949353a3ecedcdc7691cf21775818b598208fcb980c29
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 PEG3 ASCC3 HECTD1

5.41e-05194935e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellsevere-Plasmablast|World / disease stage, cell group and cell class

YIF1A SND1 WFS1 TMEM208 ENTPD1

5.41e-0519493549e8f90db571a89b8a26aef31fcacd66429fed11
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLDN11 TENM3 MRGPRF F2R TENM2

5.41e-0519493543eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 ELK3 RALGAPA2 F2R

5.54e-05195935f55ab1018a6cde7d517b53e6ce44c3f7bde485c4
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 ELK3 RALGAPA2 F2R

5.54e-05195935ea1b00805391dca8be0883b635768b296369919a
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 ELK3 RALGAPA2 F2R

5.54e-05195935126f46dd15dddcf5701144718bb8ba1ce84b2d1d
ToppCellE12.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL8A2 FRAS1 CLDN11 TENM3 PEG3

5.54e-05195935febe746099964b9ea9e75f2efc72c962c01f0421
ToppCellfacs-Aorta-Heart-3m-Endothelial|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 ENTPD1 ELK3 F2R

5.54e-051959358493f2f60fc356af28b9c0e287d4cd8c8899c081
ToppCellfacs-Aorta-Heart-3m-Endothelial-aortic_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRB SGK1 ENTPD1 ELK3 F2R

5.54e-051959355e5ca7bd94c9e924ed76f7ccac199be745d4c4eb
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRB UACA ENTPD1 ELK3 ITGA2

5.68e-05196935ccf6881c09e570116cf1bcb71112765ea8c28418
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRB UACA ENTPD1 ELK3 ITGA2

5.68e-05196935629236f95c838a473b5964a49b7c1b7ad863ea12
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRB UACA ENTPD1 ELK3 ITGA2

5.82e-05197935f4834378d5d31560b4efe5dee0d5b5d11caeb10f
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRB UACA ENTPD1 ELK3 ITGA2

5.82e-05197935dfc052a447c3b32235fcaffdf06c4e0941723d19
DrugLycorine hydrochloride [2188-68-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A

COL8A2 CLDN11 PCSK6 ENTPD1 OSBPL7 HUWE1 ROBO3

1.48e-051989173891_UP
DrugAzlocillin sodium salt [37091-65-9]; Up 200; 8.2uM; HL60; HT_HG-U133A

COL8A2 TENM3 DNAJC16 PCSK6 PEG3 OSBPL7 CRP

1.48e-051989172727_UP
Drug0317956-0000 [391210-11-0]; Up 200; 10uM; MCF7; HT_HG-U133A

PCSK6 ENTPD1 MFSD6 OSBPL7 ANKMY1 HUWE1 TRAPPC9

1.53e-051999173966_UP
DrugPF-00539758-00 [351321-34-1]; Down 200; 10uM; MCF7; HT_HG-U133A

PCSK6 CFTR UBR4 ENTPD1 ANKMY1 LTBP2 HUWE1

1.53e-051999176416_DN
Drug4-Chlorobutyramide

ADHFE1 ITGA2

1.58e-052912CID000075564
Drug1,12-dichlorododecane

CFTR ITGA2

1.58e-052912CID000077523
Drugwarburganal

ADHFE1 ITGA2

1.58e-052912CID000072502
Diseaserisky sexual behaviour measurement

XYLT1 SND1 TMEM161B ASCC3 TENM2

1.55e-04169885EFO_0007877
Diseasecalcineurin subunit B type 1 measurement

PCSK6 C6

1.83e-047882EFO_0020215
Diseasepantothenate measurement

CAD TENM2

2.43e-048882EFO_0021034
Diseasedimethylglycine measurement

FAH PCSK6 CSMD3

3.55e-0446883EFO_0010476
DiseaseDrug habituation

XYLT1 CFTR CSMD3 TENM2

3.97e-04115884C0013170
DiseaseSubstance-Related Disorders

XYLT1 CFTR CSMD3 TENM2

3.97e-04115884C0236969
DiseaseDrug abuse

XYLT1 CFTR CSMD3 TENM2

3.97e-04115884C0013146
DiseaseDrug Use Disorders

XYLT1 CFTR CSMD3 TENM2

3.97e-04115884C0013222
DiseaseDrug Dependence

XYLT1 CFTR CSMD3 TENM2

3.97e-04115884C1510472
DiseaseSubstance Dependence

XYLT1 CFTR CSMD3 TENM2

3.97e-04115884C0038580
DiseaseSubstance Use Disorders

XYLT1 CFTR CSMD3 TENM2

3.97e-04115884C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

XYLT1 CFTR CSMD3 TENM2

3.97e-04115884C0029231
DiseasePrescription Drug Abuse

XYLT1 CFTR CSMD3 TENM2

3.97e-04115884C4316881
DiseaseSubstance abuse problem

XYLT1 CFTR CSMD3 TENM2

4.10e-04116884C0740858
DiseaseTourette syndrome

XYLT1 CSMD3 TENM2

4.54e-0450883EFO_0004895
Diseaseautosomal recessive polycystic kidney disease (biomarker_via_orthology)

CFTR PANX1

4.75e-0411882DOID:0110861 (biomarker_via_orthology)
Diseaseascending aortic diameter

CCNE1 ENTPD1 DISP2 TRAPPC9

8.31e-04140884EFO_0021787
Diseaselung cancer

BRIP1 TENM2

1.78e-0321882MONDO_0008903
Diseasediabetes mellitus (implicated_via_orthology)

WFS1 CFTR

2.73e-0326882DOID:9351 (implicated_via_orthology)
Diseasecalcium measurement

CCNE1 SND1 SGK1 MRGPRF MFSD6 ASCC3 F2R

2.74e-03628887EFO_0004838
Diseasethrombocytopenia (is_implicated_in)

BRIP1 ITGA2

2.94e-0327882DOID:1588 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
HLLVSAQTFISSYYG

APH1B

196

Q8WW43
ILILHEGSSYFYGTF

CFTR

616

P13569
LSGEKYTFGSTVHYS

CSMD3

3006

Q7Z407
YLLHSLVFGSAVYSS

ACOX3

121

O15254
YELAYISSHSDFIPS

ADGRV1

3576

Q8WXG9
YGILAASALYHFSSS

CCNE1

296

P24864
SYAFSHREGYANLIT

ATP8B3

1251

O60423
SGLTTSAAFYASYLS

DISP2

596

A7MBM2
FSSLSDLIGYYSHVS

RASA1

246

P20936
FTSTLYTSLHGYFVF

RHO

91

P08100
VLYPTDAYSHLSSRT

KIAA1549

251

Q9HCM3
YFFLTHLSFIDLSYS

OR8H2

61

Q8N162
SRYSFHSLKSGSLYS

PTPRB

606

P23467
TDGHLVTDSFYFSVS

FRAS1

1796

Q86XX4
QTGLSLYSTSHGFYE

ECHDC1

26

Q9NTX5
SLTQLFSHSYGRLYA

GPC2

121

Q8N158
YSLFYTAILHFSGGE

AQP7P3

131

A6NL99
HGIEYIFGSISTTLY

CPA5

361

Q8WXQ8
ASTLATTYSSGAFYE

PCSK6

386

P29122
PASAYLADTTHTSLY

PEX6

396

Q13608
YTFTGSSCLHFSFLS

DNAJC16

646

Q9Y2G8
ASGLYRAITETHAFY

MYLIP

261

Q8WY64
SSYGGTLRYELHSET

LAMA5

1706

O15230
LGYYFSLSSLSDEFV

PANX1

231

Q96RD7
IVLDAGSSHTSLYIY

ENTPD1

51

P49961
SVLSHVSELTAYFFS

MFSD6

486

Q6ZSS7
AAITHSTYSLPASSY

NOL4L

311

Q96MY1
SHYILTLADLSSTDY

RALGAPA2

1316

Q2PPJ7
YSFSRHLYSSIEHLT

HUWE1

106

Q7Z6Z7
RNHSSYLGYSVAAIS

ITGA2

431

P17301
LASYKSYSGTFHSLE

NBPF1

846

Q3BBV0
TAAALTYGLYSFHRG

HIGD2A

56

Q9BW72
YGSSYTHTSFLTEPL

PEG3

1311

Q9GZU2
VTYGSYVFSFATTHA

MFSD4B

246

Q5TF39
YFFLTHLSFIDLSYS

OR8H3

61

Q8N146
SHTSTTEAAYFAYLL

F2R

341

P25116
YSTSPYLLEAASHLS

BRIP1

916

Q9BX63
TLSSYYVDSIISHES

HOXB9

6

P17482
TLSHLALTPSYGDTY

HLA-DMB

176

P28068
THYLSLSGFELYGTV

HECTD1

1226

Q9ULT8
SALYSRIFDDFGTHY

C6

351

P13671
YIHSGLYSSFTLNSL

ELK4

141

P28324
YSTEYIHSSFSGFLL

COL8A2

686

P25067
RVTSTDHYFLSDGLY

C5orf22

126

Q49AR2
HRETTIVSFGYSLYA

CLDN11

146

O75508
HFYTELSSTRGYSIF

CRP

56

P02741
SSFTGTFYLSHREGY

ANKMY1

46

Q9P2S6
STSRNEYIHSGLYSS

ELK3

131

P41970
EYIHSGLYSSFTINS

ELK3

136

P41970
AGHGYTYASSDIRLS

LTBP2

726

Q14767
LSSTSAIIDYLTDHY

DUS4L

301

O95620
HLPATIGDYTDFYSS

FAH

116

P16930
TSSLIGHSARVYALY

FBXW2

141

Q9UKT8
YACGFSVLLTSYTHS

DNA2

666

P51530
TAYGIGIESAHSYSF

SBK2

121

P0C263
YGLEFSIALTHSIYS

MS4A13

116

Q5J8X5
IAAFAVSAYSSTYHR

OSBPL7

536

Q9BZF2
LYASSPHSDFLDYVS

ADHFE1

151

Q8IWW8
LGIAYYDTSDSTIHF

MSH5

61

O43196
HYTSSITTKFGDSFY

PNPLA8

191

Q9NP80
SFLVGLASHLYTTYR

TAS2R42

66

Q7RTR8
SASSSLASLSRYLYH

SZT2

781

Q5T011
LESSVQLHSYFYSTH

TDRD6

966

O60522
FINTSSYGVLSYHVS

TMEM131L

171

A2VDJ0
FSTSLFGLFYHQYLT

TMEM161B

471

Q8NDZ6
YFLHLASADVGYLFS

MRGPRF

81

Q96AM1
YSEHGRILSYAASSQ

SPATA31A6

1251

Q5VVP1
FYAAEIASALGYLHS

SGK1

201

O00141
YAEGDLTLYHRTSVT

FTSJ3

241

Q8IY81
HFTAERSSYYKSLLS

SND1

631

Q7KZF4
VLRDGHSFATYFLSY

SLC25A47

186

Q6Q0C1
HTSSEITSLYYDLQG

TENM1

2286

Q9UKZ4
SEITSLYYDLQGHLF

TENM2

2341

Q9NT68
FLTTQGFLTSAYHYV

SLF2

786

Q8IX21
FSSTDLGRTASHYYI

ASCC3

976

Q8N3C0
FLAGSSVLLYYTFHS

RNFT1

211

Q5M7Z0
YSYTLLPAESFFHTV

XYLT1

521

Q86Y38
SVASHLGTTSRSYFY

TNFSF8

26

P32971
RSDLSTFHLLAYSGY

YIF1A

196

O95070
LAGVSIYISYSHLAF

TMEM235

141

A6NFC5
ETSSRTHFYAAFTLS

SEMA4G

311

Q9NTN9
ELSHYTASFAYTPAV

ROBO3

921

Q96MS0
TSYLLTYLSSHSSDF

TMCO6

151

Q96DC7
SSSEITSLYYDLQGH

TENM3

2266

Q9P273
GSFSVLLHYLSFYCT

VN1R4

21

Q7Z5H5
SLYASLGTADFYTEH

CAD

1341

P27708
ALGFSLAVYGASYHS

TMEM208

56

Q9BTX3
ISLLDALGHDSSYYA

UACA

226

Q9BZF9
DLHDTVSFVGSSTFY

TRAPPC9

1076

Q96Q05
EAFSTTAGAYLIYSS

TSPEAR

641

Q8WU66
EPFYSSFVALSTHYI

UBR4

71

Q5T4S7
GRYLATYSNTDSHIS

WDR7

1406

Q9Y4E6
AAETHYTYFPSTAVG

USF1

111

P22415
TGFFTVTSYLSLSTH

WFS1

436

O76024