Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentaggresome

BAG3 CLU EDEM1 TRIM37

1.10e-04401304GO:0016235
GeneOntologyCellularComponentciliary rootlet

KLC2 ODAD3 KLC1

1.24e-04161303GO:0035253
Domain-

CLTCL1 KLC2 TTC27 BBS4 SRP72 TTK TOMM70 TTC7B CLTC KLC1

1.76e-06207129101.25.40.10
DomainTPR-like_helical_dom

CLTCL1 KLC2 TTC27 BBS4 SRP72 TTK TOMM70 TTC7B CLTC KLC1

5.06e-0623312910IPR011990
DomainTPR_2

KLC2 TTC27 BBS4 TOMM70 TTC7B

2.40e-05501295PF07719
DomainTPR_2

KLC2 TTC27 BBS4 TOMM70 TTC7B

2.40e-05501295IPR013105
DomainTPR

KLC2 TTC27 BBS4 SRP72 TOMM70 TTC7B KLC1

3.17e-051291297SM00028
DomainTPR_1

KLC2 BBS4 SRP72 TOMM70 TTC7B KLC1

3.74e-05901296IPR001440
DomainTPR_1

KLC2 BBS4 SRP72 TOMM70 TTC7B KLC1

3.74e-05901296PF00515
DomainTPR_repeat

KLC2 TTC27 BBS4 SRP72 TOMM70 TTC7B KLC1

3.85e-051331297IPR019734
DomainClathrin_H-chain_propeller_rpt

CLTCL1 CLTC

4.73e-0521292IPR022365
DomainClathrin-link

CLTCL1 CLTC

4.73e-0521292PF09268
Domain-

CLTCL1 CLTC

4.73e-05212922.130.10.110
DomainClathrin_heavy_chain

CLTCL1 CLTC

4.73e-0521292IPR016341
DomainClathrin_H-chain_propeller_N

CLTCL1 CLTC

4.73e-0521292IPR001473
DomainClathrin_H-chain_link/propller

CLTCL1 CLTC

4.73e-0521292IPR016025
DomainClathrin_propel

CLTCL1 CLTC

4.73e-0521292PF01394
DomainClathrin_H-chain_linker_core

CLTCL1 CLTC

4.73e-0521292IPR015348
DomainTPR-contain_dom

KLC2 TTC27 BBS4 SRP72 TOMM70 TTC7B KLC1

8.26e-051501297IPR013026
DomainClathrin_H-chain_linker

CLTCL1 CLTC

1.41e-0431292IPR012331
DomainKINESIN_LIGHT

KLC2 KLC1

1.41e-0431292PS01160
DomainKinesin_light_repeat

KLC2 KLC1

1.41e-0431292IPR015792
DomainCLH

CLTCL1 CLTC

1.41e-0431292SM00299
DomainTPR_REGION

KLC2 TTC27 BBS4 SRP72 TOMM70 TTC7B KLC1

1.50e-041651297PS50293
DomainTPR

KLC2 TTC27 BBS4 SRP72 TOMM70 TTC7B KLC1

1.50e-041651297PS50005
DomainKinesin_light

KLC2 KLC1

2.81e-0441292IPR002151
DomainKinase-like_dom

ROR1 INSR CDK14 TTK PIK3R4 HIPK3 PTPN13 MAPK15 PI4KA ALPK3 MASTL PKN2

3.80e-0454212912IPR011009
DomainPDZ

IL16 FRMPD1 SHROOM4 RADIL PTPN13 SIPA1L2

4.42e-041411296PF00595
DomainQuino_amine_DH_bsu

BRWD3 NBAS OLFM3

4.50e-04221293IPR011044
DomainUPA

UNC5B UNC5C

4.67e-0451292PF17217
DomainUPA

UNC5B UNC5C

4.67e-0451292IPR033772
DomainTPR_8

BBS4 SRP72 TOMM70 TTC7B

4.89e-04531294PF13181
DomainPDZ

IL16 FRMPD1 SHROOM4 RADIL PTPN13 SIPA1L2

5.72e-041481296SM00228
Domain-

IL16 FRMPD1 SHROOM4 RADIL PTPN13 SIPA1L2

6.14e-0415012962.30.42.10
DomainPDZ

IL16 FRMPD1 SHROOM4 RADIL PTPN13 SIPA1L2

6.35e-041511296PS50106
DomainPDZ

IL16 FRMPD1 SHROOM4 RADIL PTPN13 SIPA1L2

6.58e-041521296IPR001478
DomainRab5-bind

KLC2 KLC1

6.97e-0461292PF09311
DomainRabaptin_Rab5-bd_dom

KLC2 KLC1

6.97e-0461292IPR015390
DomainTPR_10

KLC2 KLC1

6.97e-0461292PF13374
DomainClathrin

CLTCL1 CLTC

9.72e-0471292PF00637
DomainLA

LARP1B LARP4

9.72e-0471292SM00715
DomainHTH_LA

LARP1B LARP4

9.72e-0471292PS50961
DomainLa

LARP1B LARP4

9.72e-0471292PF05383
DomainCHCR

CLTCL1 CLTC

9.72e-0471292PS50236
DomainLupus_La_RNA-bd

LARP1B LARP4

9.72e-0471292IPR006630
DomainIGc2

SIGLEC12 SIGLEC8 UNC5B ROR1 UNC5C ALPK3 LILRA4

1.24e-032351297SM00408
DomainIg_sub2

SIGLEC12 SIGLEC8 UNC5B ROR1 UNC5C ALPK3 LILRA4

1.24e-032351297IPR003598
DomainClathrin_H-chain/VPS_repeat

CLTCL1 CLTC

1.29e-0381292IPR000547
DomainGlyco_hydro_47

USF3 EDEM1

1.29e-0381292IPR001382
DomainZU5

UNC5B UNC5C

1.65e-0391292SM00218
Domain-

RADIL STARD9 CEP170B

1.95e-033612932.60.200.20
DomainFHA_dom

RADIL STARD9 CEP170B

1.95e-03361293IPR000253
DomainZU5

UNC5B UNC5C

2.05e-03101292PS51145
DomainIg_I-set

SIGLEC12 SIGLEC8 UNC5B ROR1 UNC5C ALPK3

2.07e-031901296IPR013098
DomainI-set

SIGLEC12 SIGLEC8 UNC5B ROR1 UNC5C ALPK3

2.07e-031901296PF07679
DomainARM-type_fold

NCAPD3 CLTCL1 PIK3R4 XPO5 PI4KA CLTC PKP1 FMNL1

2.47e-033391298IPR016024
DomainPH_dom-like

ARHGAP24 FRMPD1 APBB2 TRIOBP CERT1 PTPN13 NGEF PLEKHH2 DCP1A

2.83e-034261299IPR011993
DomainZU5

UNC5B UNC5C

2.99e-03121292PF00791
DomainZU5_dom

UNC5B UNC5C

2.99e-03121292IPR000906
DomainDUF4599

SPATA31C2 SPATA31C1

2.99e-03121292PF15371
DomainDUF4599

SPATA31C2 SPATA31C1

2.99e-03121292IPR027970
DomainFERM_M

FRMPD1 PTPN13 PLEKHH2

3.93e-03461293PF00373
DomainWW

BAG3 APBB2 YAP1

4.18e-03471293PF00397
DomainWW

BAG3 APBB2 YAP1

4.44e-03481293SM00456
DomainPROTEIN_KINASE_ATP

ROR1 INSR CDK14 TTK PIK3R4 HIPK3 MAPK15 MASTL PKN2

4.61e-034591299PS00107
DomainSTART_lipid-bd_dom

CERT1 STARD9

4.69e-03151292IPR002913
DomainSTART

CERT1 STARD9

4.69e-03151292PF01852
DomainSTART

CERT1 STARD9

4.69e-03151292PS50848
Domain-

FRMPD1 PTPN13 PLEKHH2

4.70e-034912931.20.80.10
DomainFERM_central

FRMPD1 PTPN13 PLEKHH2

4.70e-03491293IPR019748
DomainFERM_domain

FRMPD1 PTPN13 PLEKHH2

4.70e-03491293IPR000299
DomainFERM/acyl-CoA-bd_prot_3-hlx

FRMPD1 PTPN13 PLEKHH2

4.98e-03501293IPR014352
DomainFERM_1

FRMPD1 PTPN13 PLEKHH2

4.98e-03501293PS00660
DomainFERM_2

FRMPD1 PTPN13 PLEKHH2

4.98e-03501293PS00661
DomainFERM_3

FRMPD1 PTPN13 PLEKHH2

4.98e-03501293PS50057
DomainBand_41_domain

FRMPD1 PTPN13 PLEKHH2

4.98e-03501293IPR019749
DomainB41

FRMPD1 PTPN13 PLEKHH2

4.98e-03501293SM00295
DomainWW_DOMAIN_1

BAG3 APBB2 YAP1

5.26e-03511293PS01159
DomainWW_DOMAIN_2

BAG3 APBB2 YAP1

5.26e-03511293PS50020
DomainWW_dom

BAG3 APBB2 YAP1

5.56e-03521293IPR001202
DomainSMAD_FHA_domain

RADIL STARD9 CEP170B

5.56e-03521293IPR008984
Domain-

ARHGAP24 APBB2 TRIOBP CERT1 PTPN13 NGEF PLEKHH2 DCP1A

5.82e-0339112982.30.29.30
DomainGOLGA2L5

GOLGA6L2 GOLGA8B

6.74e-03181292PF15070
DomainGolgin_A

GOLGA6L2 GOLGA8B

6.74e-03181292IPR024858
DomainProt_kinase_dom

ROR1 INSR CDK14 TTK PIK3R4 HIPK3 MAPK15 MASTL PKN2

6.90e-034891299IPR000719
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

BAG3 KLC2 LARP1B RFX7 CDK14 TTK PIK3R4 FSIP2 RADIL PTPN13 MDN1 YAP1 STARD9 PI4KA CEP131 SIPA1L2 CEP170B KLC1 DCP1A

7.41e-108611321936931259
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

RPL24 IL16 COPA KLC2 SRP72 OGDH PIK3R4 TOMM70 MLIP TTC7B PLPPR4 CLU WASHC5 PI4KA CLTC NGEF SLC4A10 SIPA1L2 CEP170B KLC1 VDAC1

1.09e-0714311322137142655
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

RPL24 KLC2 TRIOBP ZDBF2 OGDH SRPRB PLPPR4 CLU WASHC5 PI4KA SPHKAP CLTC SLC4A10 PKP1 CEP131 SIPA1L2 CEP170B VDAC1

3.34e-0711391321836417873
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FRMPD1 GON4L STRIP2 TOMM70 XPO5 STARD9 SPHKAP CLTC SIPA1L2 CEP170B SENP7

4.81e-074071321112693553
Pubmed

Siglec-9 modulated IL-4 responses in the macrophage cell line RAW264.

SIGLEC12 SIGLEC8 IL4

5.31e-075132326540411
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

UNC5B INSR APBB2 TRIOBP ITGA6 PTPN13 TTC7B GLB1 PI4KA UNC5C SIPA1L2

6.70e-074211321136976175
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

UNC5B BAG3 BMS1 TRIOBP SPG11 RBM28 OGDH TTK SRPRB NBAS PTPN13 MDN1 GLB1 CLU PI4KA CLTC CEP131 PKN2 SIPA1L2 KLC1

8.86e-0714871322033957083
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

NCAPD3 COPA BMS1 NBAS XPO5 PI4KA CLTC CRYBG1

1.12e-06202132833005030
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

KLC2 SRPRB RADIL PTPN13 TRIM32 YAP1 CEP131 SIPA1L2 TRIM37 FMNL1 CEP170B

1.18e-064461321124255178
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

ZDBF2 LARP1B PTPN13 SCML1 CEP131 SIPA1L2 CEP170B DCP1A

1.45e-06209132836779422
Pubmed

Scan of 977 nonsynonymous SNPs in CLL4 trial patients for the identification of genetic variants influencing prognosis.

IL16 CD5 LILRA4

1.85e-067132318006695
Pubmed

Defining the membrane proteome of NK cells.

RPL24 KDM3A NCAPD3 CLTCL1 COPA KLC2 LARP4 TTK PIK3R4 NBAS TOMM70 MDN1 PI4KA CLTC FMNL1 KLC1 DCP1A

2.23e-0611681321719946888
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

COPA BAG3 BMS1 TRIOBP TTC27 ITGA6 TOMM70 PTPN13 PTPRB TTC7B WASHC5 PI4KA CLTC CEP131 LTBP1 DCP1A

2.50e-0610491321627880917
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

INSR FRMPD1 APBB2 TRIOBP RTN4RL1 LARP4 CDK14 OGDH CERT1 NAALADL2 BRWD3 HIPK3 USF3 PTPN13 PTPRB FAM111A NGEF NLRC5 CEP170B

3.68e-0614891321928611215
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

ANGEL1 APBB2 ITGA6 SPG11 SRPRB PIK3R4 NBAS PTPN13 WASHC5 PI4KA WDR24

3.80e-065041321134432599
Pubmed

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.

LARP4 BRWD3 STRIP2 FMNL1

4.37e-0629132421834987
Pubmed

Dynein and kinesin regulate stress-granule and P-body dynamics.

KLC2 TIAL1 KLC1

6.29e-0610132319825938
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

KLC2 PIK3R4 RADIL YAP1 CLTC CCS KLC1 DCP1A

6.30e-06255132815324660
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

NCAPD3 ORC3 ANGEL1 GON4L SRP72 PIK3R4 TOMM70 GLB1 CLU WASHC5 TRIM32 EDEM1

7.46e-066501321238777146
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

KDM3A NCAPD3 ZEB1 COPA BAG3 KLC2 RFX7 MDN1 YAP1 CLTC PKN2 VDAC1 DCP1A

8.43e-067741321315302935
Pubmed

Analysis of Netrin 1 receptors during inner ear development.

UNC5B ITGA6 UNC5C

8.62e-0611132317616930
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

RPL24 INSR ANGEL1 BMS1 APBB2 SRPRB PTPN13 CD5 PI4KA UNC5C CLTC ADAMTS16 CEP131

8.79e-067771321335844135
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

NCAPD3 CLTCL1 COPA BMS1 TRIOBP TTC27 SRP72 RBM28 OGDH SRPRB NBAS TOMM70 MDN1 XPO5 CLU CLTC VDAC1 DCP1A

8.99e-0614401321830833792
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

RPL24 BAG3 KLC2 ITGA6 TTK YAP1 PI4KA GOLGA8B CRYBG1 PKN2 CCS

1.11e-055651321125468996
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

ZEB1 CLTCL1 ORC3 KLC2 TDG LARP4 TTK CREBZF TIAL1 YAP1 UNC5C CEP131 KLC1 SENP7

1.21e-059251321428986522
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

NCAPD3 TM9SF1 ROR1 BAG3 TTC27 ITGA6 SPG11 OGDH TOMM70 MDN1 XPO5 CLU SLC4A10 LTBP1 CEP170B

1.29e-0510611321533845483
Pubmed

Decreased neuronal CD200 expression in IL-4-deficient mice results in increased neuroinflammation in response to lipopolysaccharide.

IL4 CD200

1.43e-052132219501645
Pubmed

Knockdown of BAG3 induces epithelial-mesenchymal transition in thyroid cancer cells through ZEB1 activation.

ZEB1 BAG3

1.43e-052132224577090
Pubmed

Crystal structures of the tetratricopeptide repeat domains of kinesin light chains: insight into cargo recognition mechanisms.

KLC2 KLC1

1.43e-052132222470497
Pubmed

Genome-wide cooperation of EMT transcription factor ZEB1 with YAP and AP-1 in breast cancer.

ZEB1 YAP1

1.43e-052132232692442
Pubmed

Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.

CLTCL1 CLTC

1.43e-05213228733129
Pubmed

Opposing roles of ZEB1 in the cytoplasm and nucleus control cytoskeletal assembly and YAP1 activity.

ZEB1 YAP1

1.43e-052132236198275
Pubmed

Structural plasticity of the N-terminal capping helix of the TPR domain of kinesin light chain.

KLC2 KLC1

1.43e-052132229036226
Pubmed

The protein kinase C-related kinase PRK2 interacts with the protein tyrosine phosphatase PTP-BL via a novel PDZ domain binding motif.

PTPN13 PKN2

1.43e-052132211356191
Pubmed

Zinc-Dependent Regulation of ZEB1 and YAP1 Coactivation Promotes Epithelial-Mesenchymal Transition Plasticity and Metastasis in Pancreatic Cancer.

ZEB1 YAP1

1.43e-052132233421513
Pubmed

CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.

CLTCL1 CLTC

1.43e-052132229097553
Pubmed

ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types.

ZEB1 YAP1

1.43e-052132226876920
Pubmed

The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.

CLTCL1 CLTC

1.43e-052132220065094
Pubmed

Histone demethylase KDM3A is required for enhancer activation of hippo target genes in colorectal cancer.

KDM3A YAP1

1.43e-052132230649550
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

RPL24 COPA TTC7B WASHC5 PI4KA NGEF KANK4 PKP1 FMNL1 DCP1A

1.45e-054751321031040226
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

NCAPD3 COPA TM9SF1 BAG3 TTC27 SRP72 SRPRB TOMM70 GLB1 XPO5 TRIM32 PI4KA CLTC VDAC1

1.48e-059421321431073040
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

COPA ANGEL1 BMS1 SRP72 ZDBF2 RBM28 LARP1B LARP4 OGDH TTK SRPRB NBAS TOMM70 MDN1 PI4KA CLTC VDAC1 ATPAF2

1.50e-0514961321832877691
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

RPL24 BAG3 ITGA6 SRP72 ZC3H3 ATRIP TRIM32 ZNF804B CLTC VDAC1

1.51e-054771321031300519
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RPL24 COPA BAG3 BMS1 TTC27 RBM28 LARP4 SRPRB PIK3R4 MDN1 WASHC5 TRIM32 PI4KA CLTC PKP1 PKN2 DCP1A

1.53e-0513531321729467282
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

CLTCL1 ZGRF1 KLC2 GON4L SRP72 TDG HMCES CREBZF RADIL WASHC5 KANK4 EDEM1 SIPA1L2 TRIM37 CEP170B DCP1A

1.57e-0512151321615146197
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

ZGRF1 KLC2 ZDBF2 TTK YAP1 PI4KA CLTC CEP131 SIPA1L2 TRIM37 CEP170B

1.61e-055881321138580884
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ARHGAP24 ZEB1 TRIOBP MDN1 PLPPR4 CLU PI4KA SPHKAP CLTC NGEF GOLGA8B CEP131 CEP170B KLC1

1.89e-059631321428671696
Pubmed

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

NCAPD3 ORC3 SRPRB PI4KA CLTC VDAC1

2.44e-05150132630154076
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

SPG11 ZDBF2 RBM28 LARP4 HMCES STRIP2 NBAS GLB1 YAP1 MASTL CEP131 DCP1A

2.45e-057331321234672954
Pubmed

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.

CLTCL1 TRIOBP MDN1 RTL9 CLTC PLEKHH2 DCP1A

2.64e-05226132725900982
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RPL24 NCAPD3 COPA BMS1 SRP72 OGDH SRPRB PIK3R4 TOMM70 MAPK15 MDN1 XPO5 STARD9 PI4KA CLTC PKP1 VDAC1

2.94e-0514251321730948266
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

KDM3A COPA APBB2 TRIOBP TTC27 DCTD BRWD3 CREBZF PIK3R4 PTPN13 TTC7B CLU TRIM32 CLTC NGEF TRIM37

3.09e-0512851321635914814
Pubmed

A protein interaction landscape of breast cancer.

RBM28 DCTD OGDH TOMM70 MDN1 GLB1 XPO5 PI4KA CLTC PKP1 LTBP1

3.20e-056341321134591612
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

TM9SF1 BAG3 BMS1 TTC27 SRP72 RBM28 TOMM70 PTPN13 MDN1 TRIM32 CEP131 DCP1A

3.22e-057541321233060197
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

ZGRF1 GON4L OGDH MDN1 KIAA1549L CLTC NGEF

3.30e-05234132736243803
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZEB1 ZGRF1 BAG3 TTC27 ZDBF2 PTPN13 CEP131 KLC1 DCP1A

3.31e-05418132934709266
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

RPL24 CLTCL1 UNC5B KLC2 GLB1 TRIM32 ZNF804B SLC4A10 PKP1 SIPA1L2 TRIM37

3.44e-056391321123443559
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

RPL24 COPA ORC3 BMS1 TTC27 SRP72 RBM28 TTK SRPRB MDN1 FAM111A CCDC71 XPO5 WASHC5 CLTC CRYBG1

4.18e-0513181321630463901
Pubmed

Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.

CLTCL1 CLTC

4.28e-053132219509056
Pubmed

Role of the netrin system of repellent factors on synovial fibroblasts in rheumatoid arthritis and osteoarthritis.

UNC5B UNC5C

4.28e-053132219822088
Pubmed

Downregulation of miR-335 exhibited an oncogenic effect via promoting KDM3A/YAP1 networks in clear cell renal cell carcinoma.

KDM3A YAP1

4.28e-053132233888871
Pubmed

A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer.

ZEB1 YAP1

4.28e-053132227270433
Pubmed

The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment.

UNC5B UNC5C

4.28e-053132212655055
Pubmed

Muc5ac: a critical component mediating the rejection of enteric nematodes.

MUC5AC IL4

4.28e-053132221502330
Pubmed

UNC5C‑knockdown enhances the growth and metastasis of breast cancer cells by potentiating the integrin α6/β4 signaling pathway.

ITGA6 UNC5C

4.28e-053132231789389
Pubmed

Upregulation of MUC5AC gene expression by IL-4 through CREB in human airway epithelial cells.

MUC5AC IL4

4.28e-053132219718656
Pubmed

Electron tomography reveals Rab6 is essential to the trafficking of trans-Golgi clathrin and COPI-coated vesicles and the maintenance of Golgi cisternal number.

COPA CLTC

4.28e-053132222335553
Pubmed

Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers.

UNC5B UNC5C

4.28e-053132226859457
Pubmed

Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG.

CLTCL1 CLTC

4.28e-053132222891263
Pubmed

Taz-tead1 links cell-cell contact to zeb1 expression, proliferation, and dedifferentiation in retinal pigment epithelial cells.

ZEB1 YAP1

4.28e-053132220207963
Pubmed

Sequential dephosphorylation of a multiply phosphorylated insulin receptor peptide by protein tyrosine phosphatases.

INSR PTPRB

4.28e-05313221373652
Pubmed

Association between the polymorphisms of IL-4 gene promoter (-590C>T), IL-13 coding region (R130Q) and IL-16 gene promoter (-295T>C) and allergic asthma.

IL16 IL4

4.28e-053132217303923
Pubmed

Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers.

TTK MASTL

4.28e-053132233627787
Pubmed

Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration.

CLTCL1 CLTC

4.28e-053132215133132
Pubmed

Circ-HIPK3 regulates YAP1 expression by sponging miR-381-3p to promote oral squamous cell carcinoma development.

HIPK3 YAP1

4.28e-053132233737493
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

GOLGA6L2 BAG3 BBS4 PTPN13 GLB1 XPO5 TRIM32 YAP1 SCML1 RTL9 CEP131 MUC5AC KLC1 VDAC1 WDR24 DCP1A

4.30e-0513211321627173435
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

TAS1R3 ITGA6 FSIP2 PTPN13 YAP1 CEP131

4.60e-05168132630631154
Pubmed

Identification of novel spartin-interactors shows spartin is a multifunctional protein.

COPA KLC2 CLTC

4.95e-0519132319765186
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

TRIOBP TTK NBAS WASHC5 CEP131 PKN2 CEP170B

5.14e-05251132729778605
Pubmed

Analysis of Presenilin 1 and 2 interacting proteins in mouse cerebral cortex during development.

ROR1 ITGA6 CLTC

5.81e-0520132325196998
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

FRMPD1 ANGEL1 BBS4 RBM28 PTPN13 PI4KA SOCS5 UNC5C CLTC MASTL CRYBG1 CPLANE1 TRIM37 DCP1A

6.78e-0510841321411544199
Pubmed

Human-specific elimination of epithelial Siglec-XII suppresses the risk of inflammation-driven colorectal cancers.

SIGLEC12 SIGLEC8

8.54e-054132238990656
Pubmed

A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis.

ROR1 YAP1

8.54e-054132228114269
Pubmed

Leishmania donovani Utilize Sialic Acids for Binding and Phagocytosis in the Macrophages through Selective Utilization of Siglecs and Impair the Innate Immune Arm.

SIGLEC12 SIGLEC8

8.54e-054132227494323
Pubmed

Siglec-9 acts as an immune-checkpoint molecule on macrophages in glioblastoma, restricting T-cell priming and immunotherapy response.

SIGLEC12 SIGLEC8

8.54e-054132237460871
Pubmed

Group B Streptococcus engages an inhibitory Siglec through sialic acid mimicry to blunt innate immune and inflammatory responses in vivo.

SIGLEC12 SIGLEC8

8.54e-054132224391502
Pubmed

CD200 ligand receptor interaction modulates microglial activation in vivo and in vitro: a role for IL-4.

IL4 CD200

8.54e-054132217670977
Pubmed

Cayman ataxia protein caytaxin is transported by kinesin along neurites through binding to kinesin light chains.

KLC2 KLC1

8.54e-054132219861499
Pubmed

The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis.

SIGLEC12 SIGLEC8

8.54e-054132238454157
Pubmed

Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells.

SIGLEC12 SIGLEC8

8.54e-054132230130255
Pubmed

Siglec receptors impact mammalian lifespan by modulating oxidative stress.

SIGLEC12 SIGLEC8

8.54e-054132225846707
Pubmed

Immunosuppressive Siglec-E ligands on mouse aorta are up-regulated by LPS via NF-κB pathway.

SIGLEC12 SIGLEC8

8.54e-054132231918287
Pubmed

IL4, IL10, IL16, and TNF polymorphisms in New Zealand Caucasian Crohn's disease patients.

IL16 IL4

8.54e-054132217576577
Pubmed

Sialylated ligands on pathogenic Trypanosoma cruzi interact with Siglec-E (sialic acid-binding Ig-like lectin-E).

SIGLEC12 SIGLEC8

8.54e-054132219552697
Pubmed

Targeting the Siglec-sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma.

SIGLEC12 SIGLEC8

8.54e-054132237467314
Pubmed

Polysialic acid promotes remyelination in cerebellar slice cultures by Siglec-E-dependent modulation of microglia polarization.

SIGLEC12 SIGLEC8

8.54e-054132237492129
Pubmed

The human sialic acid-binding immunoglobulin-like lectin Siglec-9 and its murine homolog Siglec-E control osteoclast activity and bone resorption.

SIGLEC12 SIGLEC8

8.54e-054132233007530
Pubmed

The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase.

UNC5B UNC5C

8.54e-054132215729359
Pubmed

The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell development.

SOCS5 IL4

8.54e-054132217611223
Pubmed

Insulin-Inducible SMILE Inhibits Hepatic Gluconeogenesis.

INSR CREBZF

8.54e-054132226340929
InteractionYWHAG interactions

BAG3 KLC2 LARP1B RFX7 CDK14 TTK PIK3R4 RADIL PTPN13 MDN1 TRIM32 YAP1 STARD9 PI4KA CLTC CEP131 PKN2 SIPA1L2 CEP170B CCS KLC1 DCP1A

1.18e-05124812822int:YWHAG
InteractionEPHA2 interactions

UNC5B ROR1 INSR APBB2 TRIOBP ITGA6 SRPRB PTPN13 TTC7B GLB1 PI4KA UNC5C CLTC CCR1 SIPA1L2 KLC1

1.32e-0571912816int:EPHA2
InteractionCEP128 interactions

COPA SRP72 ZDBF2 TTK WASHC5 CEP131 PKN2 SIPA1L2 TRIM37 CEP170B

2.04e-0529712810int:CEP128
Cytoband3q12

RPL24 SENP7

8.16e-05513223q12
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

KLC2 TTC27 BBS4 SRP72 TOMM70 TTC7B KLC1

8.99e-07115827769
GeneFamilyPDZ domain containing

IL16 FRMPD1 SHROOM4 RADIL PTPN13 SIPA1L2

6.62e-051528261220
GeneFamilyLa ribonucleoprotein domain containing|RNA binding motif containing

LARP1B LARP4

4.20e-047822625
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

SIGLEC12 UNC5B ROR1 UNC5C ALPK3

8.27e-04161825593
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

FRMPD1 PTPN13 PLEKHH2

1.51e-03508231293
GeneFamilyStAR related lipid transfer domain containing

CERT1 STARD9

2.05e-0315822759
GeneFamilyBardet-Biedl syndrome associated|BBSome

BBS4 TRIM32

4.03e-0321822980
CoexpressionHE_LIM_SUN_FETAL_LUNG_C4_CYCLING_T_CELL

NCAPD3 ZEB1 ORC3 ZGRF1 BAG3 TRIOBP ITGA6 LARP4 ZC3H3 TTK HMCES TOMM70 CD5 FAM111A ATRIP PI4KA SCML1 MASTL CEP131

2.00e-0793913019M45768
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

KDM3A ZEB1 ROR1 APBB2 ITGA6 SPG11 TDG LARP4 TTK PIK3R4 NBAS PTPN13 MDN1 YAP1 SOCS5 PKN2 TRIM37 KLC1

2.47e-0785613018M4500
CoexpressionGSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP

CREBZF PTPN13 TIAL1 SCML1 GOLGA8B CRYBG1 FMNL1 KLC1

7.32e-062001308M9889
CoexpressionGSE11386_NAIVE_VS_MEMORY_BCELL_DN

INSR RFX7 PTPN13 CD5 MDN1 SOCS5 NLRC5

1.44e-051581307M372
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

IL16 ARHGAP24 ROR1 NAALADL2 YAP1 UNC5C LTBP1 PLEKHH2

1.28e-071971318f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UNC5B LARP1B SHROOM4 PTPRB CLTC SIPA1L2 CD200

1.24e-061841317c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCelldroplet-Liver-Hepatocytes-21m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZEB1 TMEM158 ITGA6 TDG PTPRB TTC7B ODAD3

1.29e-061851317efcfbf5a48b3ea9a425183e5c2eec6a9585415a0
ToppCelldroplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZEB1 TMEM158 ITGA6 TDG PTPRB TTC7B ODAD3

1.29e-061851317642088ace9230d38b0579853c54ff4dd8b5d5df4
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

ZEB1 ROR1 APBB2 YAP1 UNC5C LTBP1 PLEKHH2

1.71e-061931317e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

ROR1 APBB2 YAP1 UNC5C ADAMTS16 LTBP1 PLEKHH2

1.96e-061971317f1c8936986123a3151140c374fcd62d6705c530b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZEB1 PTPN13 CD5 MLIP YAP1 CRYBG1

1.02e-05167131683969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

BMS1 ZDBF2 ZC3H3 NLRC5 MUC5AC CEP170B

1.20e-051721316d65ffff3e341af34a043a0d802d7ba4b69de36e9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRMPD1 APBB2 CDK14 UNC5C ADAMTS16 ALPK3

1.24e-0517313164bc6d93716f093b460c8b047199db8cab5fea720
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPD3 ZGRF1 TTK PTPRB FAM111A MASTL

1.29e-051741316c988471207ba06195bc3e41056435e8c31c20bbe
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRMPD1 APBB2 CDK14 UNC5C ADAMTS16 ALPK3

1.61e-051811316e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM158 STRIP2 RGS8 KIAA1549L PLPPR4 FMNL1

1.66e-051821316d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM158 STRIP2 RGS8 KIAA1549L PLPPR4 FMNL1

1.66e-0518213166cde859edfe7607bd7ada89d20258413d06f4207
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RTN4RL1 VIT TG MLIP ZNF804B NGEF

1.66e-05182131635b2a5625323bf0917214d3b82fafc4a8f5e75ff
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RTN4RL1 VIT TG MLIP ZNF804B NGEF

1.76e-0518413169a185e6ea86bbfbb48bfe88650a8c05ceba78d7f
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

APBB2 RTN4RL1 MLIP YAP1 NGEF KANK4

1.82e-0518513161d874608aa2062024323512f68889219471b2f00
ToppCelldroplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM158 ZDBF2 SHROOM4 PTPRB CLU CD200

1.88e-0518613165d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D175|Adult / Lineage, Cell type, age group and donor

ZEB1 ITGA6 SHROOM4 PTPRB TTC7B PKP1

1.93e-051871316f3548817f2fded5978137bb252cb628ac199e4f6
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UNC5B TMEM158 APBB2 PTPRB CLU CD200

2.05e-0518913169da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCellfacs-GAT-Fat-24m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5B APBB2 ITGA6 PTPRB TRIM37 CD200

2.11e-051901316da2fcd4a2cc6e45c8174109d892f1424e39919a1
ToppCellfacs-GAT-Fat-24m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5B APBB2 ITGA6 PTPRB TRIM37 CD200

2.11e-0519013163395b2ff6ffadf84cdb1b5a37a5b6be05b56c30f
ToppCellfacs-Heart-LA-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APBB2 ITGA6 PTPRB CLU TRIM37 CD200

2.11e-051901316911b93c4c828ef2d867b91a5eced2dc12a1baf27
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5B APBB2 ITGA6 PTPRB TRIM37 CD200

2.11e-051901316c8370c922e0cf0e0c36e02e1ed2b4053ad6a8073
ToppCellfacs-GAT-Fat-24m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5B APBB2 ITGA6 PTPRB TRIM37 CD200

2.11e-051901316e584eaccbc22aa7f7a4340ed8a2a8b45ddca93f4
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5B APBB2 ITGA6 PTPRB TRIM37 CD200

2.11e-0519013165174f91a880f85bb20806023aa68bd4b8ca24ea5
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5B APBB2 ITGA6 PTPRB TRIM37 CD200

2.11e-05190131690e494cbfbed33a3a0d29bb7dae83f0c81580bcf
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UNC5B TMEM158 APBB2 PTPRB CLU CD200

2.18e-0519113163307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ZDBF2 OLFM3 SPHKAP SLC4A10 RESP18 CEP170B

2.18e-0519113165d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ZDBF2 OLFM3 SPHKAP SLC4A10 RESP18 CEP170B

2.18e-05191131673dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDBF2 MLIP KIAA1549L PLPPR4 SPHKAP RESP18

2.31e-051931316461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDBF2 MLIP KIAA1549L PLPPR4 SPHKAP RESP18

2.31e-0519313160dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANGEL1 ITGA6 SHROOM4 PTPRB LTBP1 SIPA1L2

2.31e-051931316e1d546165dcc2392f540162206852c4717d7306f
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZEB1 ITGA6 PTPN13 CD5 GOLGA8B CRYBG1

2.31e-051931316194b49c152e3e3f599068ec88a7f0af6427b743a
ToppCellLA|World / Chamber and Cluster_Paper

IL16 ZEB1 APBB2 VIT UNC5C PLEKHH2

2.31e-051931316d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

RPL24 ROR1 RADIL SPHKAP UNC5C PLEKHH2

2.38e-05194131628c5482da199bcee9e85258a88af453d9fdbd56a
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZEB1 UNC5B ITGA6 SHROOM4 PTPRB SIPA1L2

2.38e-05194131643f92b0533e26633dc94cce554045d641ef8fd76
ToppCellCOPD-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

INSR HIPK3 SHROOM4 MDN1 VDAC1 CD200

2.38e-0519413168dcde77767b23e75360adb316cdccf56a00e3726
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZEB1 APBB2 ITGA6 SHROOM4 PTPRB SIPA1L2

2.38e-0519413160b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZEB1 UNC5B ITGA6 SHROOM4 PTPRB SIPA1L2

2.38e-0519413161d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellfacs-Heart-LA-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM158 APBB2 ITGA6 PTPRB TRIM37 CD200

2.38e-05194131633cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CDK14 OLFM3 MLIP KIAA1549L NGEF SLC4A10

2.45e-0519513162e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ORC3 SIGLEC8 VIT CD5 PLPPR4 ADAMTS16

2.45e-051951316e5b0afbea85575851cf9eb50a9ac42c67bbf3d7c
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP24 ROR1 APBB2 RFX7 NAALADL2 YAP1

2.52e-051961316ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ROR1 CDK14 NAALADL2 UNC5C PKN2 PLEKHH2

2.52e-0519613161450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCellCOPD-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

ZEB1 PTPN13 CD5 CLU SCML1 CRYBG1

2.52e-051961316c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NAALADL2 YAP1 SPHKAP UNC5C PKN2 PLEKHH2

2.59e-0519713160034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

ROR1 APBB2 YAP1 UNC5C LTBP1 PLEKHH2

2.59e-051971316fb847f2277609c31fffcdf49517243ce0684facf
ToppCellmetastatic_Brain-Endothelial_cells|metastatic_Brain / Location, Cell class and cell subclass

UNC5B INSR ITGA6 SHROOM4 PTPRB CD200

2.67e-05198131697ef7946ef11ac93318c1dd46b548dc01e5a6aba
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP24 ROR1 APBB2 NAALADL2 PTPN13 YAP1

2.67e-0519813161996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellmetastatic_Brain-Endothelial_cells-Tumor_ECs|metastatic_Brain / Location, Cell class and cell subclass

UNC5B INSR ITGA6 SHROOM4 PTPRB CD200

2.67e-0519813165e274f29cc796dae7d64d6035e904816c25f9914
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZEB1 ROR1 VIT PTPN13 MLIP STARD9

2.74e-0519913163835452e4848d7f7dd8651c17b746b271ef39688
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ZEB1 ITGA6 SHROOM4 PTPRB SIPA1L2 CD200

2.82e-05200131672ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellBiopsy_Other_PF-Endothelial|Biopsy_Other_PF / Sample group, Lineage and Cell type

ZEB1 ITGA6 SHROOM4 PTPRB CLU CD200

2.82e-052001316f9916134486fb1dac55f5e7e8deb35e7a3b85770
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ZEB1 ITGA6 SHROOM4 PTPRB SIPA1L2 CD200

2.82e-0520013165c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial-Astrocyte|GW10 / Sample Type, Dataset, Time_group, and Cell type.

ZEB1 FAM111A KIAA1549L CLU YAP1 STARD9

2.82e-05200131698a994692440cb4f505b050276f0c8022c814a21
ToppCellBiopsy_Other_PF-Endothelial-Endothelial_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

ZEB1 ITGA6 SHROOM4 PTPRB CLU CD200

2.82e-05200131640d57a383c79d3365e033d08efd9371f0bc5bf55
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial|GW10 / Sample Type, Dataset, Time_group, and Cell type.

ZEB1 FAM111A KIAA1549L CLU YAP1 STARD9

2.82e-052001316ef222dc4a205d670172dae74990bdb952ac92e5b
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_monocytic-monocyte|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SIGLEC8 INSR BAG3 SPATA31C2 ALPK3

3.44e-051251315a72891c3fb9cdefa9254f8e2e3c4ffa6fc3a5ffc
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Spindle_Cell-2|TCGA-Uvea / Sample_Type by Project: Shred V9

ZDBF2 NAALADL2 PIK3R4 USF3 DCP1A

5.14e-051361315b460669c13ed43ff3885acd38ce18f75d693738d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BAG3 STARD9 ZNF804B ADAMTS16 LTBP1

5.90e-0514013152c44e8cc5190226049be7ebc465d685393e701c4
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|343B / Donor, Lineage, Cell class and subclass (all cells)

BMS1 ZDBF2 ZC3H3 NLRC5 MUC5AC

7.92e-0514913152a7f71da51c85e04de2123164914122480e60d66
ToppCellDendritic_Cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

IL16 ZEB1 CRYBG1 FMNL1 LILRA4

8.44e-051511315e089bf197ed60e7243160521d4390d4b40a3832b
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP24 APBB2 TRIOBP USF3 CD200

9.26e-0515413151f8d127b657976656e4ec292f26d619943533b86
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLTCL1 RADIL MDN1 MASTL CEP131

9.26e-05154131516fdafb5c64d2db321554f87129a962d113f1668
ToppCell343B-Myeloid-Dendritic-pDC|343B / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP24 FRMPD1 EDEM1 MS4A6A LILRA4

9.84e-051561315547e2debfc09c07c049a880dded5fda7dd53e156
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRMPD1 APBB2 CDK14 UNC5C ADAMTS16

1.11e-0416013158bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRMPD1 APBB2 CDK14 UNC5C ADAMTS16

1.11e-0416013152d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tregs|GI_large-bowel / Manually curated celltypes from each tissue

CLTCL1 ZDBF2 PTPN13 CD5 CD200

1.17e-0416213159a5e65c45f73a6a685b8362aa2e6aea77181caa3
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDBF2 CDK14 MLIP ZNF804B RESP18

1.28e-0416513156d8b5669eee9b0903c9260fea707d186c9d7fefa
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDBF2 CDK14 MLIP ZNF804B RESP18

1.28e-04165131502cd87dfa2ca40e13455a4b9308477e82f76289b
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TDG MAPK15 PI4KA ZNF804B RESP18

1.32e-04166131566026988509e39e41274fa0de738383219e8ff30
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTK FAM111A XPO5 MASTL CCR1

1.39e-04168131552fd65024af8683db11d931f7563cbe8eb815d1c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MLIP ZNF804B ADAMTS16 PKP1 PLEKHH2

1.51e-0417113159d5cabd71a901a00eb16c4d151189296f1b3bf6f
ToppCellNS-critical-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ITGA6 MAPK15 NGEF CPLANE1 CD200

1.73e-041761315b794275fdd757b8fa2108e3c867f23da2649146d
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UNC5B TMEM158 CD5 PTPRB CLU

1.73e-04176131527e6b3ae41068d6cfdda3d46da7df2a27567140e
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

TMEM158 ZDBF2 OGDH HIPK3 FSIP2

1.73e-0417613157a74217b7fa1032b918f00a3972dff5fab74671a
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UNC5B TMEM158 CD5 PTPRB CLU

1.73e-041761315d6a5470af9592f34a741265f2ea9651c05c3add3
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROR1 PTPN13 CLU ADAMTS16 PLEKHH2

1.78e-041771315b7fee75de7e96924af488a5baa2334711889ae7c
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM158 APBB2 PTPRB CLU CD200

1.78e-0417713156f6cf93893daac6ae228df36219ee3acf8de8f97
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLIP KIAA1549L CLU ALPK3 KANK4

1.82e-0417813155cf12927f0756c4d8a289fe4308d736382e6212e
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

APBB2 PTPRB CLU TRIM37 CD200

1.82e-041781315ebfae386a518ea33911ba3ff40464c94d18ef695
ToppCellT_cells-TFH-like_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

CDK14 PTPN13 SIPA1L2 MS4A6A CD200

1.82e-041781315e2ae43e5ec31de6197f2cbd6089f944adbf0a163
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

APBB2 PTPRB CLU TRIM37 CD200

1.82e-041781315ccd37575b60102f5e647c01546e8ff8fec638bd7
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OLFM3 MAPK15 ZNF804B ADAMTS16 PLEKHH2

1.82e-0417813150e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

APBB2 PTPRB CLU TRIM37 CD200

1.82e-04178131587b04753650e45f12299c8456fb980d6c0d5961c
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM158 APBB2 SHROOM4 PTPRB CD200

1.87e-041791315a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRMPD1 APBB2 NAALADL2 UNC5C ADAMTS16

1.87e-041791315666072c0e8448dbaec1683d18368ec2502453f90
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

APBB2 ITGA6 BRWD3 PTPRB ATRIP

1.92e-041801315baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CLTCL1 VIT RADIL OLFM3 ZNF804B

1.92e-041801315f598bb9df0d784120847fada2d9a2a88b8b68cd1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STARD9 SOCS5 RTL9 UNC5C LTBP1

1.92e-041801315280ff5c8f292be1b88120db5ff1788b750644856
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CLTCL1 VIT RADIL OLFM3 ZNF804B

1.92e-041801315b4fa047f271c7b56940bdc85c912f50aa5b5ca82
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STARD9 SOCS5 RTL9 UNC5C LTBP1

1.92e-041801315fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCellICU-NoSEP-Myeloid-tDC|ICU-NoSEP / Disease, Lineage and Cell Type

ZDBF2 CD5 GLB1 CPLANE1 LILRA4

1.92e-041801315be665e801512f6aaf6b3ecb26153bbdeb24619ac
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

APBB2 ITGA6 BRWD3 PTPRB ATRIP

1.92e-0418013152d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

APBB2 ITGA6 BRWD3 PTPRB ATRIP

1.92e-0418013150f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPD3 ARHGAP24 TTK FAM111A PKP1

1.97e-041811315b203b616584cdbd0bbb0e382b2916d0bd49d3526
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPD3 ARHGAP24 TTK FAM111A PKP1

1.97e-041811315c748c16fd20d1949d33ff6290dc9d9016c4dc86c
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ROR1 MLIP SPHKAP ALPK3 LTBP1

1.97e-041811315719eb532453ab7cd7893726885bc75d74a10b21e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RTN4RL1 TG MLIP ZNF804B NGEF

2.02e-041821315cc6f9d606a4f8717dc44928ceec2a257636043fd
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZGRF1 DCTD TTK TG MASTL

2.02e-0418213153948422707d6d5e021bcd7158e2eb69143613f62
Drug17-AAG; Up 200; 1uM; PC3; HG-U133A

ZEB1 BAG3 APBB2 GON4L LARP4 CREBZF CD5 CLU DCP1A

1.86e-061951309450_UP
DrugAC1L1IPS

CLTCL1 TG CLTC

3.59e-0661303CID000004682
Diseaseamygdala volume change measurement

SPATA31C2 SPATA31C1 ZNF804B

4.38e-05161293EFO_0021490
Diseasenetrin receptor UNC5B measurement

UNC5B UNC5C

1.13e-0441292EFO_0802792
Diseaserenal overload-type gout

SPATA31C2 SPATA31C1

2.81e-0461292EFO_0021525
Diseaseperipheral vascular disease

HIPK3 KIAA1549L

3.93e-0471292EFO_0003875
Diseaseprostate-specific antigen measurement, disease progression measurement

SPHKAP NGEF

3.93e-0471292EFO_0008336, EFO_0020660
DiseaseAlzheimer's disease 1 (implicated_via_orthology)

KLC2 KLC1

3.93e-0471292DOID:0080348 (implicated_via_orthology)
Diseasesialic acid-binding Ig-like lectin 6 measurement

SIGLEC12 SIGLEC8

5.22e-0481292EFO_0008285
Diseaseeosinophil cationic protein measurement

SPATA31C2 SPATA31C1

5.22e-0481292EFO_0010913
Diseaselongitudinal alcohol consumption measurement

SPATA31C2 SPATA31C1

6.69e-0491292EFO_0007645
DiseaseAutoimmune Diseases

COPA TG IL4

8.27e-04421293C0004364
Diseaseresponse to escitalopram, response to citalopram

APBB2 PLPPR4

8.34e-04101292EFO_0006329, EFO_0007871
Diseaseallergic rhinitis (biomarker_via_orthology)

MUC5AC IL4

8.34e-04101292DOID:4481 (biomarker_via_orthology)
DiseaseBardet-Biedl syndrome (implicated_via_orthology)

BBS4 CEP131

1.02e-03111292DOID:1935 (implicated_via_orthology)
Diseaseegg allergy measurement, parental genotype effect measurement

SPATA31C2 SPATA31C1

1.43e-03131292EFO_0005939, EFO_0007018
Diseaserhinitis (biomarker_via_orthology)

MUC5AC IL4

1.43e-03131292DOID:4483 (biomarker_via_orthology)
Diseasepeanut allergy measurement

ARHGAP24 ITGA6

2.19e-03161292EFO_0007017
Diseasepolycystic ovary syndrome

INSR YAP1 UNC5C

2.33e-03601293EFO_0000660
DiseaseBardet-Biedl syndrome 1 (disorder)

BBS4 TRIM32

2.47e-03171292C2936862
Diseaserenal fibrosis (implicated_via_orthology)

CLU RESP18

2.47e-03171292DOID:0050855 (implicated_via_orthology)
DiseaseAllergic Reaction

IL16 CCR1 IL4

2.68e-03631293C1527304
DiseaseBardet-Biedl syndrome

BBS4 TRIM32

2.77e-03181292cv:C0752166
DiseaseHypersensitivity

IL16 CCR1 IL4

2.80e-03641293C0020517
DiseaseParkinson disease

BAG3 TIAL1 CLU RTL9 NGEF SIPA1L2

2.94e-033211296MONDO_0005180
DiseaseJoubert syndrome 1

CPLANE1 TRIM37

3.77e-03211292C4551568

Protein segments in the cluster

PeptideGeneStartEntry
QIDPDACFSAKVNNS

VDAC1

226

P21796
SSSARCAQFPRAQDK

TDG

271

Q13569
QTCAVLSPQSADNLK

BBS4

91

Q96RK4
KALACSSLQERANVN

APBB2

556

Q92870
EKNQDPANILSACLS

MASTL

226

Q96GX5
KAAQSRRSSENCIPS

ALPK3

536

Q96L96
PDFQARLTRSNSKCQ

CD5

31

P06127
IARFLQSGPCNKSAQ

BRWD3

16

Q6RI45
QCSPKNRLSAQAALS

CDK14

401

O94921
SQACPLSEKRNADNH

BVES-AS1

26

Q5T3Y7
NDSCEDALANKTRPR

CEP170B

1411

Q9Y4F5
LSPANCQSDRVNLEK

BMS1

551

Q14692
AARDKQSPSQANGCS

DCP1A

136

Q9NPI6
NSQKCPRDSVDFRAA

ADAMTS16

636

Q8TE57
SQQERDQAKLTCPSE

MLIP

86

Q5VWP3
CTNPRNRNQISKAGA

RTN4RL1

356

Q86UN2
QEAAQKCLLAASPEN

RBM28

386

Q9NW13
KQAQLQEPISLASCA

RADIL

481

Q96JH8
DSAPLNNRCVRAKIN

CERT1

536

Q9Y5P4
DKIQNLHCRPQNSTA

PTPRB

1356

P23467
RCSQEANSRKDNAPF

LILRA4

476

P59901
VCSQHSPANRKLVQA

MDN1

2396

Q9NU22
LCNTSLDNPTQRNKD

ATPAF2

111

Q8N5M1
RDQKPSNVLLDANCT

MAPK15

136

Q8TD08
SAHTLRNAKDLNCQP

LRRC53

236

A6NM62
RNAKDLNCQPSTAAV

LRRC53

241

A6NM62
SNITDAFLSQRKCEP

GLB1

246

P16278
SRCAKENQLSLPDQS

FSIP2

5431

Q5CZC0
ASLCDNVLAPNVTKQ

LTBP1

1356

Q14766
SNRKSLSQQLDCPAG

IL16

171

Q14005
NELSPLKLRCQANAA

PI4KA

426

P42356
CHSPEDTQQNRAQLK

GOLGA6L2

66

Q8N9W4
SELCAPFTESKNRQQ

KIAA1549L

1451

Q6ZVL6
KTQAACPNIRNSFED

MUC5AC

601

P98088
RNDIALKTNGDQASC

INSR

481

P06213
RAFPEKQLSCVANQN

ITGA6

756

P23229
ARVNDSERNPNLSCK

CYHR1

266

Q6ZMK1
CDTNNHNKTSLLRPV

HIPK3

556

Q9H422
DANRCFEKQSPSALS

NBAS

1556

A2RRP1
KTCQLFINAAVDSPA

PLEKHH2

981

Q8IVE3
CPQLKEVSFRDNQLS

NLRC5

741

Q86WI3
DDPNVAKTKNNLASC

KLC2

361

Q9H0B6
PASLKCSLQNAQEAL

CD200

46

P41217
AAQNPENVKRLLFCT

OGDH

891

Q02218
KENNNTKDSPSRQCS

ARHGAP24

361

Q8N264
SPLAKVNRDQCFTSE

RESP18

156

Q5W5W9
CTANPPSQTKLQARA

CCDC71

76

Q8IV32
NSCPVKEANQSTLEN

IL4

121

P05112
CCSRSNNKIQNAPSR

KDM3A

496

Q9Y4C1
QKTQRNEFTAQLPDC

CPLANE1

2026

Q9H799
ATPCQKVNERAFGAQ

CCR1

21

P32246
SAQRSKDPNSQVGAC

DCTD

26

P32321
NPAENAVLLCTRASN

COPA

371

P53621
LAQRANPQCQKTEFS

FRMPD1

661

Q5SYB0
NPQCQKTEFSESAAL

FRMPD1

666

Q5SYB0
AAASQNPESEKRNTC

FAM111A

276

Q96PZ2
QPKAAEATVCANNSK

GON4L

2131

Q3T8J9
ARSAGLFQNPKQICS

CCS

231

O14618
KVINSSSNCNRVPDE

EDEM1

621

Q92611
SVKQATLNPASLQCE

MS4A6A

136

Q9H2W1
SLQCELDKNNIPTRS

MS4A6A

146

Q9H2W1
ASPCNNNINAATAVA

LARP4

596

Q71RC2
PACVNEIALSLNNKN

FMNL1

251

O95466
KPSEEFLNACRALSQ

KANK4

746

Q5T7N3
LASQALSQCPAAARD

ATRIP

66

Q8WXE1
ESVIKSNLPNCANSD

CRYBG1

966

Q9Y4K1
ARQSPCQEQAAVLNS

GOLGA8B

66

A8MQT2
QPDKQCGQVAAAAAA

BAG3

146

O95817
RKECTVALAPNFTAN

CEP131

156

Q9UPN4
DPSKLQFNTTNCRSD

HMCES

86

Q96FZ2
APEQNLCSRDAKSRQ

OLFM3

71

Q96PB7
DDPNVAKTKNNLASC

KLC1

376

Q07866
SRNSSRCQPEANKPT

LARP1B

96

Q659C4
LSCNSEQKPDRSQAI

PTPN13

186

Q12923
CNLPEAKRRINFLSN

ORC3

346

Q9UBD5
NNIINLCRSSASPKA

PKP1

686

Q13835
SSQVLPTACKRNNEE

RTL9

1321

Q8NET4
TRKNLQEPSLTCFDQ

RGS8

131

P57771
TLPRNDANLCDANKV

SENP7

116

Q9BQF6
KDVPSACAVAEQRSN

SPHKAP

351

Q2M3C7
PSQAEKCANRLAASR

SPHKAP

1341

Q2M3C7
FVNKEPNIVSDASCN

SCML1

36

Q9UN30
NTPSFLIACNKQDIA

SRPRB

171

Q9Y5M8
AKQRGPEAASNIQQC

TRIM32

341

Q13049
SCNDPTKNIIREFAS

TRIM37

351

O94972
LQASSPACKQFQRAP

SPATA31C2

731

B4DYI2
PSKNSSRRNQNCATE

SOCS5

71

O75159
IDNSQACSSALRKPA

STRIP2

176

Q9ULQ0
CRAASANALPPQDQA

ODAD3

6

A5D8V7
KARDNPERNASCLAD

NGEF

76

Q8N5V2
CLRQASNSPKVSEQL

SIPA1L2

581

Q9P2F8
AETQACLRNHNPSSK

SIGLEC8

481

Q9NYZ4
KACDRASSVDSNPLN

SHROOM4

371

Q9ULL8
AGRPQCKQIDQSSSD

STARD9

2591

Q9P2P6
NNDPRCSTSNNRLKA

PKN2

126

Q16513
RLQASSPACKQFQRA

SPATA31C1

736

P0DKV0
EQCRKISASLQSQSP

SRP72

321

O76094
PQTNNCSLSIRDARK

SIGLEC12

226

Q96PQ1
NSRTSCAQRDNPKAS

TRIOBP

401

Q9H2D6
NPARTAQDCLAALAQ

PNMA6A

216

P0CW24
TCRKNVLLANSSSPQ

ANGEL1

26

Q9UNK9
QCTAFLLDALKNNRP

CLTC

561

Q00610
QCTSFLLDALKNNRP

CLTCL1

561

P53675
NVRSPARNKDTPACS

NCAPD3

1471

P42695
VDCSTNNPSQAKLRR

CLU

311

P10909
CVCRNNQKSSSAPVQ

ROR1

426

Q01973
IRLNSAQNCLPFQKA

PIK3R4

76

Q99570
SQQPDRCKRAQAFIS

SPG11

2026

Q96JI7
AEKTVACNRSNSQPR

PLPPR4

561

Q7Z2D5
DNQKPVSRCSRQCQE

TAS1R3

491

Q7RTX0
PSLQEAALAAACSNR

ZC3H3

891

Q8IXZ2
RNTLKNTLENCVNHP

ZNF804B

346

A4D1E1
ADSACDPNNKRLRQI

WASHC5

381

Q12768
CESAFLSKRNPRQIN

RPL24

36

P83731
NSCPSKAQVVSNDLQ

SPEM3

1076

A0A1B0GUW6
EAAAAAAPCNISVQR

TMEM158

66

Q8WZ71
PACVENKNDVSRENS

SLC4A10

266

Q6U841
ASLTRKSNVNQQCPA

nan

541

Q9UF83
RNINPSTANSPKCQE

YAP1

331

P46937
STANSPKCQELALRS

YAP1

336

P46937
DNNQAATKSPRKAAA

CREBZF

201

Q9NS37
KCNLVDIGQATNNRS

ZDBF2

161

Q9HCK1
KAQANCRVGVAALNT

XPO5

216

Q9HAV4
VEPNFANKAVCRTNG

VIT

441

Q6UXI7
RPESALAQAQKCFAL

TOMM70

431

O94826
AANKSACPLNSVRDV

USF3

806

Q68DE3
DACANNIAQRSQSVP

RFX7

1116

Q2KHR2
SIRQKICNSLDAPNS

UNC5B

861

Q8IZJ1
NSVPCLRALAANKQT

ZEB1

821

P37275
KPAEATACTQEAANL

TTC7B

711

Q86TV6
RKSECINQNPAASSN

TTK

391

P33981
NTSQCNVATPNRVDK

ZGRF1

1151

Q86YA3
KRSVPCESNEANEAN

SPANXB1

11

Q9NS25
DAPANAISVCRDAAQ

WDR24

26

Q96S15
AKAFQRCVTLEPDNA

TTC27

581

Q6P3X3
VSCLRQKPANVLNDA

TG

2451

P01266
LRFEDVVNQSSPKNC

TIAL1

191

Q01085
SLKNQSLARQTDPSC

UNC5C

516

O95185
NNASPFDAPCRTKNI

TM9SF1

436

O15321
ARTKNEACSSLELPN

NAALADL2

396

Q58DX5