Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium ion binding	PITPNM1 CELSR1 EGF HMCN1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3 PCDH15 LRP1 PLCB2 PLCB3 FBN3 CDH15 ITPR3	1.52e-07	749	88	16	GO:0005509
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	MAG CELSR1 HMCN1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3 PCDH15 MDGA2 CDH15	8.29e-08	313	87	11	GO:0098742
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	CELSR1 HMCN1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3 PCDH15 CDH15	9.53e-08	187	87	9	GO:0007156
GeneOntologyBiologicalProcess	cell-cell adhesion	MAG CELSR1 EFNB3 HMCN1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3 PCDH15 MDGA2 NKAP TNXB ALOX12 CDH15	4.07e-05	1077	87	15	GO:0098609
Domain	Cadherin_CS	CELSR1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3 PCDH15 CDH15	4.95e-08	109	89	8	IPR020894
Domain	CADHERIN_1	CELSR1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3 PCDH15 CDH15	6.57e-08	113	89	8	PS00232
Domain	Cadherin	CELSR1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3 PCDH15 CDH15	6.57e-08	113	89	8	PF00028
Domain	CADHERIN_2	CELSR1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3 PCDH15 CDH15	7.04e-08	114	89	8	PS50268
Domain	-	CELSR1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3 PCDH15 CDH15	7.04e-08	114	89	8	2.60.40.60
Domain	CA	CELSR1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3 PCDH15 CDH15	7.53e-08	115	89	8	SM00112
Domain	Cadherin-like	CELSR1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3 PCDH15 CDH15	8.06e-08	116	89	8	IPR015919
Domain	Cadherin	CELSR1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3 PCDH15 CDH15	9.21e-08	118	89	8	IPR002126
Domain	Cadherin_tail	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	8.48e-07	37	89	5	PF15974
Domain	Cadherin_CBD	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	8.48e-07	37	89	5	IPR031904
Domain	Cadherin_C	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	1.62e-06	42	89	5	IPR032455
Domain	Cadherin_C_2	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	1.62e-06	42	89	5	PF16492
Domain	Cadherin_2	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	1.45e-05	65	89	5	PF08266
Domain	Cadherin_N	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	1.45e-05	65	89	5	IPR013164
Domain	EGF	CELSR1 EGF HMCN1 LRP1 TNXB FBN3	3.08e-05	126	89	6	PF00008
Domain	IF5A_HYPUSINE	EIF5A EIF5A2	6.72e-05	3	89	2	PS00302
Domain	Transl_elong_IF5A_C	EIF5A EIF5A2	6.72e-05	3	89	2	IPR020189
Domain	Transl_elong_IF5A	EIF5A EIF5A2	6.72e-05	3	89	2	IPR001884
Domain	eIF-5a	EIF5A EIF5A2	6.72e-05	3	89	2	PF01287
Domain	PLC-beta_C	PLCB2 PLCB3	6.72e-05	3	89	2	PF08703
Domain	PLC-beta_C	PLCB2 PLCB3	6.72e-05	3	89	2	IPR014815
Domain	Trans_elong_IF5A_hypusine_site	EIF5A EIF5A2	6.72e-05	3	89	2	IPR019769
Domain	eIF-5a	EIF5A EIF5A2	6.72e-05	3	89	2	SM01376
Domain	Growth_fac_rcpt_	CELSR1 EGF HMCN1 LRP1 TNXB FBN3	1.01e-04	156	89	6	IPR009030
Domain	ASX_HYDROXYL	CELSR1 EGF HMCN1 LRP1 FBN3	1.16e-04	100	89	5	PS00010
Domain	PLC-beta	PLCB2 PLCB3	1.34e-04	4	89	2	IPR016280
Domain	EGF-type_Asp/Asn_hydroxyl_site	CELSR1 EGF HMCN1 LRP1 FBN3	1.52e-04	106	89	5	IPR000152
Domain	cEGF	HMCN1 LRP1 FBN3	2.51e-04	26	89	3	PF12662
Domain	cEGF	HMCN1 LRP1 FBN3	2.51e-04	26	89	3	IPR026823
Domain	EGF_CA	CELSR1 EGF HMCN1 LRP1 FBN3	2.93e-04	122	89	5	SM00179
Domain	EGF-like_Ca-bd_dom	CELSR1 EGF HMCN1 LRP1 FBN3	3.16e-04	124	89	5	IPR001881
Domain	EGF_CA	EGF HMCN1 LRP1 FBN3	7.60e-04	86	89	4	PF07645
Domain	EGF	CELSR1 EGF HMCN1 LRP1 TNXB FBN3	9.06e-04	235	89	6	SM00181
Domain	EGF_3	CELSR1 EGF HMCN1 LRP1 TNXB FBN3	9.06e-04	235	89	6	PS50026
Domain	EGF_Ca-bd_CS	EGF HMCN1 LRP1 FBN3	1.19e-03	97	89	4	IPR018097
Domain	KOW	EIF5A EIF5A2	1.20e-03	11	89	2	IPR005824
Domain	GFP-like	EGF HMCN1	1.20e-03	11	89	2	IPR023413
Domain	KOW	EIF5A EIF5A2	1.20e-03	11	89	2	PF00467
Domain	-	EGF HMCN1	1.20e-03	11	89	2	2.40.155.10
Domain	EGF-like_dom	CELSR1 EGF HMCN1 LRP1 TNXB FBN3	1.22e-03	249	89	6	IPR000742
Domain	EGF_CA	EGF HMCN1 LRP1 FBN3	1.28e-03	99	89	4	PS01187
Domain	EGF_1	CELSR1 EGF HMCN1 LRP1 TNXB FBN3	1.38e-03	255	89	6	PS00022
Domain	EGF-like_CS	CELSR1 EGF HMCN1 LRP1 TNXB FBN3	1.55e-03	261	89	6	IPR013032
Domain	EGF_2	CELSR1 EGF HMCN1 LRP1 TNXB FBN3	1.68e-03	265	89	6	PS01186
Domain	Ldl_recept_b	EGF LRP1	1.97e-03	14	89	2	PF00058
Domain	LDLRB	EGF LRP1	1.97e-03	14	89	2	PS51120
Domain	EF-hand_like	PLCB2 PLCB3	2.26e-03	15	89	2	PF09279
Domain	PI-PLC-Y	PLCB2 PLCB3	2.26e-03	15	89	2	PF00387
Domain	PLCYc	PLCB2 PLCB3	2.26e-03	15	89	2	SM00149
Domain	LY	EGF LRP1	2.26e-03	15	89	2	SM00135
Domain	PLipase_C_Pinositol-sp_Y	PLCB2 PLCB3	2.26e-03	15	89	2	IPR001711
Domain	PIPLC_Y_DOMAIN	PLCB2 PLCB3	2.26e-03	15	89	2	PS50008
Domain	PI-PLC_fam	PLCB2 PLCB3	2.26e-03	15	89	2	IPR001192
Domain	PLC_EF-hand-like	PLCB2 PLCB3	2.26e-03	15	89	2	IPR015359
Domain	LDLR_classB_rpt	EGF LRP1	2.26e-03	15	89	2	IPR000033
Domain	Laminin_G	CELSR1 COL20A1 CSPG4	2.67e-03	58	89	3	IPR001791
Domain	Translation_prot_SH3-like	EIF5A EIF5A2	2.91e-03	17	89	2	IPR008991
Domain	Rib_L2_dom2	EIF5A EIF5A2	3.27e-03	18	89	2	IPR014722
Domain	PI-PLC-X	PLCB2 PLCB3	3.27e-03	18	89	2	PF00388
Domain	PLCXc	PLCB2 PLCB3	3.27e-03	18	89	2	SM00148
Domain	-	EIF5A EIF5A2	3.27e-03	18	89	2	2.30.30.30
Domain	PIPLC_X_DOMAIN	PLCB2 PLCB3	3.64e-03	19	89	2	PS50007
Domain	PLipase_C_PInositol-sp_X_dom	PLCB2 PLCB3	3.64e-03	19	89	2	IPR000909
Domain	ConA-like_dom	CELSR1 COL20A1 CSPG4 MDGA2 RFPL2	3.96e-03	219	89	5	IPR013320
Domain	DS_RBD	ADAR SON	4.45e-03	21	89	2	PS50137
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY	PLCB2 PLCB3 ITPR3	1.10e-05	10	65	3	M47661
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY	PLCB2 PLCB3 ITPR3	1.50e-05	11	65	3	M49033
Pathway	KEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY	PLCB2 PLCB3 ITPR3	2.59e-05	13	65	3	M47656
Pathway	WP_GPR40_PATHWAY	PLCB2 PLCB3 ITPR3	4.09e-05	15	65	3	M39526
Pathway	KEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY	PLCB2 PLCB3 ITPR3	1.01e-04	20	65	3	M47688
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY	PLCB2 PLCB3 ITPR3	1.17e-04	21	65	3	M47689
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	PLCB2 PLCB3 ITPR3	1.35e-04	22	65	3	M47690
Pathway	KEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY	PLCB2 PLCB3 ITPR3	1.35e-04	22	65	3	M47675
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	PLCB2 PLCB3 ITPR3	1.55e-04	23	65	3	M47676
Pathway	REACTOME_HYPUSINE_SYNTHESIS_FROM_EIF5A_LYSINE	EIF5A EIF5A2	2.07e-04	5	65	2	MM14823
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY	PLCB2 PLCB3	3.10e-04	6	65	2	M47548
Pathway	WP_ALZHEIMERS_DISEASE	LRP1 PLCB2 PLCB3 ITPR3	3.72e-04	74	65	4	MM15962
Pathway	KEGG_MEDICUS_REFERENCE_CASR_PTH_SIGNALING_PATHWAY	PLCB2 PLCB3	4.33e-04	7	65	2	M47505
Pathway	REACTOME_ACETYLCHOLINE_REGULATES_INSULIN_SECRETION	PLCB2 PLCB3	5.76e-04	8	65	2	MM15032
Pathway	REACTOME_FATTY_ACIDS_BOUND_TO_GPR40_FFAR1_REGULATE_INSULIN_SECRETION	PLCB2 PLCB3	5.76e-04	8	65	2	M27356
Pathway	REACTOME_FATTY_ACIDS_BOUND_TO_GPR40_FFAR1_REGULATE_INSULIN_SECRETION	PLCB2 PLCB3	5.76e-04	8	65	2	MM15100
Pathway	KEGG_GAP_JUNCTION	EGF PLCB2 PLCB3 ITPR3	7.81e-04	90	65	4	M4013
Pathway	KEGG_MEDICUS_REFERENCE_TAC3_TACR3_PLC_PKC_SIGNALING_PATHWAY	PLCB2 PLCB3	9.20e-04	10	65	2	M47644
Pathway	REACTOME_ACETYLCHOLINE_REGULATES_INSULIN_SECRETION	PLCB2 PLCB3	9.20e-04	10	65	2	M1825
Pathway	KEGG_ALZHEIMERS_DISEASE	LRP1 PLCB2 PLCB3 ATP5F1A ITPR3	9.96e-04	166	65	5	M16024
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	EMILIN3 LOXL4 FBN3	1.08e-03	44	65	3	M26969
Pathway	REACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION	PLCB2 PLCB3	1.12e-03	11	65	2	M27317
Pathway	REACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION	PLCB2 PLCB3	1.12e-03	11	65	2	MM15035
Pathway	KEGG_MEDICUS_REFERENCE_KISS1_KISS1R_PLCB_PKC_SIGNALING_PATHWAY	PLCB2 PLCB3	1.12e-03	11	65	2	M47637
Pathway	KEGG_MEDICUS_REFERENCE_TRH_TRHR_PLCB_PKC_SIGNALING_PATHWAY	PLCB2 PLCB3	1.34e-03	12	65	2	M47649
Pathway	KEGG_MEDICUS_REFERENCE_TSH_DUOX2_TG_SIGNALING_PATHWAY	PLCB2 PLCB3	1.34e-03	12	65	2	M47628
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	CELSR1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	3.94e-08	72	92	6	10380929
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	CELSR1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	5.92e-08	77	92	6	10835267
Pubmed	Maturation of postnatally generated olfactory bulb granule cells depends on functional γ-protocadherin expression.	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA3	6.12e-08	15	92	4	23515096
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	CELSR1 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	7.45e-08	80	92	6	10716726
Pubmed	Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA3	8.94e-07	28	92	4	15347688
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	1.06e-06	68	92	5	11230163
Pubmed	Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx.	PLCB2 PLCB3 ITPR3	1.49e-06	9	92	3	15623527
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	1.62e-06	74	92	5	10817752
Pubmed	Functional significance of isoform diversification in the protocadherin gamma gene cluster.	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA3	2.00e-06	34	92	4	22884324
Pubmed	A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-gamma gene cluster.	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA3	5.74e-06	44	92	4	19029045
Pubmed	Ankyrin-B directs membrane tethering of periaxin and is required for maintenance of lens fiber cell hexagonal shape and mechanics.	ANK2 PRX	6.92e-06	2	92	2	26538089
Pubmed	Dual roles for lysine 490 of promyelocytic leukemia protein in the transactivation of glucocorticoid receptor-interacting protein 1.	NCOA2 PML	6.92e-06	2	92	2	23542129
Pubmed	A subset of broadly responsive Type III taste cells contribute to the detection of bitter, sweet and umami stimuli.	PLCB3 ITPR3	6.92e-06	2	92	2	32790785
Pubmed	Comparative sequence and x-inactivation analyses of a domain of escape in human xp11.2 and the conserved segment in mouse.	KDM5C IQSEC2	6.92e-06	2	92	2	15197169
Pubmed	Revisiting ankyrin-InsP3 receptor interactions: ankyrin-B associates with the cytoplasmic N-terminus of the InsP3 receptor.	ANK2 ITPR3	6.92e-06	2	92	2	18275062
Pubmed	The role of eIF5A in epidermal growth factor-induced proliferation of corneal epithelial cell association with PI3-k/Akt activation.	EGF EIF5A	6.92e-06	2	92	2	21224998
Pubmed	Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle.	PLCB2 PLCB3 ITPR3	7.96e-06	15	92	3	28578927
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	ERCC4 AZGP1 ADAR DDB1 DDX27 ATP5F1A SON PML ITPR3 NCOA5	9.08e-06	652	92	10	31180492
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	CNNM3 USP5 GTF3C1 UGDH DPYSL5 EIF5A LRP1 APLP2 CC2D1A DDB1 DDX27 ITPR3	1.01e-05	974	92	12	28675297
Pubmed	Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA3	1.63e-05	57	92	4	32633719
Pubmed	Regulating ankyrin dynamics: Roles of sigma-1 receptors.	ANK2 ITPR3	2.07e-05	3	92	2	11149946
Pubmed	Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression.	EIF5A EIF5A2	2.07e-05	3	92	2	11161802
Pubmed	Suppression of PLCbeta2 by endotoxin plays a role in the adenosine A(2A) receptor-mediated switch of macrophages from an inflammatory to an angiogenic phenotype.	MYD88 PLCB2	2.07e-05	3	92	2	19850892
Pubmed	Phospholipase C beta3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice.	PLCB2 PLCB3	2.07e-05	3	92	2	18079968
Pubmed	The relative role of PLCbeta and PI3Kgamma in platelet activation.	PLCB2 PLCB3	2.07e-05	3	92	2	15705797
Pubmed	Cell-surface glycoprotein of oligodendrocyte progenitors involved in migration.	MAG CSPG4	2.07e-05	3	92	2	10366628
Pubmed	Regulation of phospholipase C-beta 3 activity by Na+/H+ exchanger regulatory factor 2.	PLCB2 PLCB3	2.07e-05	3	92	2	10748023
Pubmed	Identification and characterization of eukaryotic initiation factor 5A-2.	EIF5A EIF5A2	2.07e-05	3	92	2	14622290
Pubmed	Phospholipase cbeta is critical for T cell chemotaxis.	PLCB2 PLCB3	2.07e-05	3	92	2	17675482
Pubmed	New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape.	EIF5A EIF5A2	2.07e-05	3	92	2	36848144
Pubmed	LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.	MAG LRP1	2.07e-05	3	92	2	24129569
Pubmed	Differential expression of eIF5A-1 and eIF5A-2 in human cancer cells.	EIF5A EIF5A2	2.07e-05	3	92	2	16519677
Pubmed	Xp11.2 microduplications including IQSEC2, TSPYL2 and KDM5C genes in patients with neurodevelopmental disorders.	KDM5C IQSEC2	2.07e-05	3	92	2	26059843
Pubmed	Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells.	PCDH15 CDH15	2.07e-05	3	92	2	17805295
Pubmed	Epidermal growth factor increases coactivation of the androgen receptor in recurrent prostate cancer.	NCOA2 EGF	2.07e-05	3	92	2	14662770
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	HMCN1 COL20A1 EMILIN3 TNXB	2.58e-05	64	92	4	22261194
Pubmed	Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.	PLCB2 PLCB3 ITPR3	3.48e-05	24	92	3	10843712
Pubmed	Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation.	MAG ANK2 CSPG4	3.95e-05	25	92	3	32266943
Pubmed	Patterns of expression for the mRNA corresponding to the four isoforms of phospholipase Cbeta in mouse brain.	PLCB2 PLCB3	4.14e-05	4	92	2	9753089
Pubmed	Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction.	PLCB2 PLCB3	4.14e-05	4	92	2	10669417
Pubmed	The mouse BP-1 gene: structure, chromosomal localization, and regulation of expression by type I interferons and interleukin-7.	EGF ANK2	4.14e-05	4	92	2	8660964
Pubmed	PML regulates apoptosis at endoplasmic reticulum by modulating calcium release.	PML ITPR3	4.14e-05	4	92	2	21030605
Pubmed	Phosphoinositide binding specificity among phospholipase C isozymes as determined by photo-cross-linking to novel substrate and product analogs.	PLCB2 PLCB3	4.14e-05	4	92	2	9188725
Pubmed	Myelin-derived ephrinB3 restricts axonal regeneration and recovery after adult CNS injury.	MAG EFNB3	4.14e-05	4	92	2	22411787
Pubmed	Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.	EIF5A EIF5A2	4.14e-05	4	92	2	22927971
Pubmed	DHPS-dependent hypusination of eIF5A1/2 is necessary for TGFβ/fibronectin-induced breast cancer metastasis and associates with prognostically unfavorable genomic alterations in TP53.	EIF5A EIF5A2	4.14e-05	4	92	2	31558321
Pubmed	The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A).	EIF5A EIF5A2	4.14e-05	4	92	2	16452303
Pubmed	Phospholipase C isozymes selectively couple to specific neurotransmitter receptors.	PLCB2 PLCB3	4.14e-05	4	92	2	9305844
Pubmed	Expression of phospholipase C beta family isoenzymes in C2C12 myoblasts during terminal differentiation.	PLCB2 PLCB3	4.14e-05	4	92	2	15174099
Pubmed	A PLCβ/PI3Kγ-GSK3 signaling pathway regulates cofilin phosphatase slingshot2 and neutrophil polarization and chemotaxis.	PLCB2 PLCB3	4.14e-05	4	92	2	22172670
Pubmed	APP, APLP2 and LRP1 interact with PCSK9 but are not required for PCSK9-mediated degradation of the LDLR in vivo.	LRP1 APLP2	4.14e-05	4	92	2	28495363
Pubmed	TRPM4 and PLCβ3 contribute to normal behavioral responses to an array of sweeteners and carbohydrates but PLCβ3 is not needed for taste-driven licking for glucose.	PLCB3 ITPR3	4.14e-05	4	92	2	38183495
Pubmed	Phospholipase C-β1 potentiates glucose-stimulated insulin secretion.	PLCB2 PLCB3	4.14e-05	4	92	2	31268747
Pubmed	PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq.	PLCB2 PLCB3	4.14e-05	4	92	2	23006664
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	AZGP1 EIF5A EMILIN3 MCRIP1 ADAR DDB1 DDX27	5.31e-05	364	92	7	24778252
Pubmed	Biological Relevance and Therapeutic Potential of the Hypusine Modification System.	EIF5A EIF5A2	6.89e-05	5	92	2	26037925
Pubmed	Regulatory interactions between the amino terminus of G-protein betagamma subunits and the catalytic domain of phospholipase Cbeta2.	PLCB2 PLCB3	6.89e-05	5	92	2	15611108
Pubmed	Gnb isoforms control a signaling pathway comprising Rac1, Plcβ2, and Plcβ3 leading to LFA-1 activation and neutrophil arrest in vivo.	PLCB2 PLCB3	6.89e-05	5	92	2	26468229
Pubmed	The TRPM7 channel is inactivated by PIP(2) hydrolysis.	PLCB2 PLCB3	6.89e-05	5	92	2	11941371
Pubmed	Neurotrophin binding to human alpha 2-macroglobulin under apparent equilibrium conditions.	NTF4 LRP1	6.89e-05	5	92	2	7537086
Pubmed	Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.	USP5 SBF2 DDB1 ATP5F1A	8.63e-05	87	92	4	17148452
Pubmed	Expression and immunohistochemical localization of eight phospholipase C isoforms in adult male mouse cerebellar cortex.	PLCB2 PLCB3	1.03e-04	6	92	2	8739298
Pubmed	Purkinje cell degeneration associated with erythroid ankyrin deficiency in nb/nb mice.	EGF ANK2	1.03e-04	6	92	2	1716634
Pubmed	GPCR activation of Ras and PI3Kc in neutrophils depends on PLCb2/b3 and the RasGEF RasGRP4.	PLCB2 PLCB3	1.03e-04	6	92	2	22728827
Pubmed	Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5.	PLCB2 PLCB3	1.03e-04	6	92	2	19647226
Pubmed	Polysialic acid as an antigen for monoclonal antibody HIgM12 to treat multiple sclerosis and other neurodegenerative disorders.	MAG CSPG4	1.03e-04	6	92	2	25866077
Pubmed	Protective roles of adenosine A1, A2A, and A3 receptors in skeletal muscle ischemia and reperfusion injury.	PLCB2 PLCB3	1.03e-04	6	92	2	17921328
Pubmed	Purification and characterization of membrane-bound phospholipase C specific for phosphoinositides from human platelets.	PLCB2 PLCB3	1.03e-04	6	92	2	2841328
Pubmed	Expression of Six1 and Six4 in mouse taste buds.	PLCB2 ITPR3	1.03e-04	6	92	2	20668922
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ANK2 GTF3C1 PCDHGA12 COL20A1 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3 CSPG4 PDE10A ATP5F1A PRX RPS6KC1	1.07e-04	1442	92	13	35575683
Pubmed	Regulation of Hyaluronan (HA) Metabolism Mediated by HYBID (Hyaluronan-binding Protein Involved in HA Depolymerization, KIAA1199) and HA Synthases in Growth Factor-stimulated Fibroblasts.	EGF HAS1	1.44e-04	7	92	2	26518873
Pubmed	Frontline Science: TNF-α and GM-CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K-γ, and neutrophil proinflammatory responses.	PLCB2 PLCB3	1.44e-04	7	92	2	30720883
Pubmed	Differential expression of individual gamma-protocadherins during mouse brain development.	PCDHGA12 PCDHGA3	1.44e-04	7	92	2	15964765
Pubmed	Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development.	KDM5C IQSEC2	1.44e-04	7	92	2	15669143
Pubmed	Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1.	LRP1 APLP2	1.44e-04	7	92	2	17920016
Pubmed	From arrest to escape: HIV-1 Vpr cuts a deal.	ERCC4 DDB1	1.44e-04	7	92	2	24528857
Pubmed	Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein lipase, alpha-2-macroglobulin and the 40,000 molecular weight receptor-associated protein.	LRP1 APLP2	1.44e-04	7	92	2	7542371
Pubmed	Longitudinal neuroanatomical and behavioral analyses show phenotypic drift and variability in the Ts65Dn mouse model of Down syndrome.	MAG CSPG4	1.44e-04	7	92	2	32817053
Pubmed	Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.	LRP1 APLP2	1.44e-04	7	92	2	19005074
Pubmed	Genetic dissection of gustatory sensitivity to bitterness (sucrose octaacetate) in mice.	PLCB2 PLCB3	1.44e-04	7	92	2	10609087
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	ERCC4 GTF3C1 ADAR DDX27 PML RPS6KC1 ITPR3	1.72e-04	440	92	7	34244565
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ARHGEF40 GCAT KDM5C LRP1 EMILIN3 NKAP DDB1 UNC80 CDH15 SON PML	1.77e-04	1116	92	11	31753913
Pubmed	Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues.	MAG APLP2 PDE10A	1.91e-04	42	92	3	15146195
Pubmed	Association between common variation in genes encoding sweet taste signaling components and human sucrose perception.	PLCB2 ITPR3	1.92e-04	8	92	2	20660057
Pubmed	Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB.	EGF HAS1	1.92e-04	8	92	2	17324121
Pubmed	Role of the cellular prion protein in oligodendrocyte precursor cell proliferation and differentiation in the developing and adult mouse CNS.	MAG CSPG4	1.92e-04	8	92	2	22529900
Pubmed	Confirmed rare copy number variants implicate novel genes in schizophrenia.	SGCE PDE10A	2.46e-04	9	92	2	20298200
Pubmed	Combined in silico and in vivo analyses reveal role of Hes1 in taste cell differentiation.	PLCB2 ITPR3	2.46e-04	9	92	2	19343206
Pubmed	Auditory cortex interneuron development requires cadherins operating hair-cell mechanoelectrical transduction.	PCDH15 CDH15	2.46e-04	9	92	2	28705869
Pubmed	Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor.	PCDHGA12 PCDHGA6	2.46e-04	9	92	2	19956686
Pubmed	Switching of α-Catenin From Epithelial to Neuronal Type During Lens Epithelial Cell Differentiation.	ANK2 PRX	2.46e-04	9	92	2	28692740
Pubmed	Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2.	LRP1 APLP2	2.46e-04	9	92	2	11247302
Pubmed	APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice.	LRP1 APLP2	2.46e-04	9	92	2	23986861
Pubmed	Exogenous human immunodeficiency virus type-1 Tat protein selectively stimulates a phosphatidylinositol-specific phospholipase C nuclear pathway in the Jurkat T cell line.	PLCB2 PLCB3	2.46e-04	9	92	2	7589147
Pubmed	A PAK5-DNPEP-USP4 axis dictates breast cancer growth and metastasis.	PRX PML	2.46e-04	9	92	2	31219614
Pubmed	BDNF+/- mice exhibit deficits in oligodendrocyte lineage cells of the basal forebrain.	MAG CSPG4	2.46e-04	9	92	2	20091777
Pubmed	Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat.	PLCB2 PLCB3	2.46e-04	9	92	2	10501179
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	KDM5C ZC3H11B APLP2 DNAH5 ADAR SON	2.59e-04	332	92	6	37433992
Pubmed	Defining the membrane proteome of NK cells.	CNNM3 PIGA GTF3C1 HPS6 EIF5A APLP2 CC2D1A ADAR APOBR ATP5F1A ITPR3	2.62e-04	1168	92	11	19946888
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	SLC22A18AS LRP1 LOXL4 DNAH5 ITPR3	2.68e-04	214	92	5	22199357
Interaction	RYK interactions	CNNM3 CELSR1 EFNB3 PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 CSPG4 APLP2 SGCE	4.11e-08	212	91	10	int:RYK
Interaction	PCDHGA4 interactions	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	4.21e-07	34	91	5	int:PCDHGA4
Interaction	PCDHGA7 interactions	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5	4.58e-06	25	91	4	int:PCDHGA7
Cytoband	5q31	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	3.73e-06	115	92	5	5q31
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	3.46e-04	298	92	5	chr5q31
GeneFamily	Clustered protocadherins	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	2.84e-06	64	63	5	20
Coexpression	NABA_MATRISOME_HIGHLY_METASTATIC_MELANOMA_TUMOR_CELL_DERIVED	HMCN1 CSPG4 EMILIN3 LOXL4	6.59e-08	12	91	4	M47983
Coexpression	NABA_MATRISOME_HIGHLY_METASTATIC_MELANOMA	HMCN1 CSPG4 EMILIN3 LOXL4	4.01e-07	18	91	4	M47984
ToppCell	Basal_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	EFNB3 HMCN1 NTF4 MDGA2 FJX1 PDE10A	9.48e-07	158	92	6	51e3ed1b91b010404d66e3e7efdbffc0c815e25b
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HMCN1 UGDH LRP1 ADGRA1 HAS1 TNXB	1.66e-06	174	92	6	1d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	EFNB3 ANK2 EMILIN3 SGCE HAS1 TNXB	2.94e-06	192	92	6	4ed5040594ba2d0639f0990697504ecef872ca70
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	EFNB3 ANK2 EMILIN3 SGCE HAS1 TNXB	2.94e-06	192	92	6	d4f5d6653564c2c5d0f5f7c932d89cb1b1412844
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 HMCN1 PCDH15 LRP1 SGCE DNAH5	3.31e-06	196	92	6	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 HMCN1 PCDH15 LRP1 SGCE DNAH5	3.31e-06	196	92	6	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CSPG4 PCDH15 LRP1 MDGA2 ADGRA1 UNC80	3.61e-06	199	92	6	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CSPG4 PCDH15 LRP1 MDGA2 ADGRA1 UNC80	3.61e-06	199	92	6	e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAG EGF COL20A1 UNC80 PRX	2.30e-05	164	92	5	3caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PITPNM1 MAG COL20A1 LRP1 APOBR	3.14e-05	175	92	5	c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCell	droplet-Limb_Muscle-nan-21m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	3.79e-05	182	92	5	a51cbdb8d6528a82044be838c70c492fc6370891
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG CELSR1 COL20A1 UNC80 PRX	3.79e-05	182	92	5	c00e503f442d44fbae73c5e2dc85be69e294e67a
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 PCDH15 MDGA2 DNAH5 UNC80	3.99e-05	184	92	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 PCDH15 MDGA2 DNAH5 UNC80	3.99e-05	184	92	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 PCDH15 MDGA2 DNAH5 UNC80	3.99e-05	184	92	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	REC8 EFNB3 PCDH15 ADGRA1 HAS1	4.10e-05	185	92	5	11fbea1eb1d9a3e4480d0d2b0f7b02e2866b8142
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 COL20A1 LRP1 SGCE TNXB	4.10e-05	185	92	5	785c55d39909fac74415f24427979691e7e694e6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 COL20A1 LRP1 SGCE TNXB	4.10e-05	185	92	5	97a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell	droplet-Liver-Npc-18m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF40 ERCC4 ZNF407 ZBTB12 ALOX12	4.21e-05	186	92	5	75258d88e23112fd1f0f7c71ef0366abb400d33e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REC8 EMILIN3 LONRF2 UNC80 CDH15	4.31e-05	187	92	5	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.42e-05	188	92	5	2cfa41c64eccb28b5e22f0f91bbc921b75713245
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSPG4 UGDH PCDH15 LRP1 DNAH5	4.42e-05	188	92	5	a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	ANK2 HMCN1 LRP1 HAS1 TNXB	4.42e-05	188	92	5	409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSPG4 UGDH PCDH15 LRP1 DNAH5	4.42e-05	188	92	5	c8530c9ff98666c64a94683261af4288cb790a7e
ToppCell	droplet-Fat-SCAT-30m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGCE HAS1 TNXB PRX CDH15	4.54e-05	189	92	5	8161910a19089f8cc5a3f1fda039f41a2488f04f
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.54e-05	189	92	5	6e52cac679e0541ca5f2be316bdabdbc34da6e18
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.54e-05	189	92	5	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.54e-05	189	92	5	56f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCell	droplet-Fat-SCAT\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGCE HAS1 TNXB PRX CDH15	4.54e-05	189	92	5	264c59de2adb8bee5bb57633d79d530a8829617b
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.65e-05	190	92	5	bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.65e-05	190	92	5	e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.65e-05	190	92	5	ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG COL20A1 DPYSL5 UNC80 PRX	4.65e-05	190	92	5	e2481bd5166fde2cdc0c3824894f2bccb8294fdd
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL20A1 AZGP1 CSPG4 PCDH15 TMEM200C	4.65e-05	190	92	5	6c7e1086c0a274cd5527c3104106e372811c9905
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.65e-05	190	92	5	f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.65e-05	190	92	5	ad0f5605db6b694445ec9bd5dc8d2d834358c0f9
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.65e-05	190	92	5	c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.65e-05	190	92	5	47077579496c5340e99f61499427a3a36b566da3
ToppCell	droplet-Mammary_Gland-nan-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.77e-05	191	92	5	8022059e434fd411dc539819f969bd4f94861281
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 PDK4 UGDH HAS1 TNXB	4.77e-05	191	92	5	f5ce33af56178333730be308253943c54a0724cf
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.77e-05	191	92	5	83d1915835df6f2eb23f87986d695e71398edb9d
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.77e-05	191	92	5	a57cf0519d749febc0b69fe0b098b7ba53d63258
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	4.77e-05	191	92	5	19c67a812b8ce97472d316acd15aeefe8736000d
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UGDH LRP1 SGCE HAS1 TNXB	4.89e-05	192	92	5	321850b0f881420c2d57d3e825e365c82fa511ab
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UGDH LRP1 SGCE HAS1 TNXB	4.89e-05	192	92	5	fc940f91ff8e051631dbf25e6e8d73cf8337eccb
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 PDK4 UGDH HAS1 TNXB	4.89e-05	192	92	5	a8b7c539dc3037071bf068f372e4215563e11de4
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UGDH LRP1 SGCE HAS1 TNXB	4.89e-05	192	92	5	7a2e79490e4f7058bb76b46c45b5df9f729e3146
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UGDH LRP1 SGCE HAS1 TNXB	4.89e-05	192	92	5	cf2765d8bc074f7f9ee864eae632a3b705175842
ToppCell	facs-Trachea-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UGDH LRP1 SGCE HAS1 TNXB	4.89e-05	192	92	5	e8af6ad1ae99cae13a82d0d8d7f38af9b777f0ba
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 PDK4 UGDH HAS1 TNXB	4.89e-05	192	92	5	2143e1fad2e88b90d668e12af37b2092d379090f
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK2 PDK4 UGDH HAS1 TNXB	4.89e-05	192	92	5	904c003c4f73b1dfc8243cee02aad2676c515e50
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UGDH LRP1 SGCE HAS1 TNXB	5.01e-05	193	92	5	25248b8e65d558b1a96a87c93e3e5b4c0ba168fe
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UGDH LRP1 SGCE HAS1 TNXB	5.01e-05	193	92	5	f1f1097204e07a7bed416425b8256942038a734f
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	5.01e-05	193	92	5	160691b671710be10220803d788c2c961c236af1
ToppCell	IPF-Stromal-Fibroblast\|Stromal / Disease state, Lineage and Cell class	UGDH LRP1 HAS1 LONRF2 TNXB	5.14e-05	194	92	5	da3e1d39575969a069ef43e552afe94b2f441d0b
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UGDH LRP1 LOXL4 HAS1 TNXB	5.26e-05	195	92	5	0feb6ebe7b4b781dec7cfaef844140cfbf84b4b9
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UGDH LRP1 LOXL4 HAS1 TNXB	5.26e-05	195	92	5	2a6f67875cef140b0e6b8401436719675c6b3665
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK2 COL20A1 EMILIN3 MDGA2 ITPR3	5.26e-05	195	92	5	9fea1ddb68da83ca43dd8006c9e51295b1817f0e
ToppCell	facs-Trachea-18m-Mesenchymal\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UGDH LRP1 SGCE HAS1 TNXB	5.26e-05	195	92	5	0d1876f6fdc1eafeb60d6fd7da5bce737d2b4a5a
ToppCell	facs-SCAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	5.39e-05	196	92	5	65f2f51e17f1869f3468813127b96d3048d8ad41
ToppCell	facs-SCAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	5.39e-05	196	92	5	e4ed897900a6472738bc6be2fb4817192727225d
ToppCell	(5)_Fibroblast-J_(Lipofibroblast)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ANK2 SGCE HAS1 TNXB TMEM200C	5.39e-05	196	92	5	afa29399decd17fda7d63add5039ff778627ccc2
ToppCell	facs-SCAT-Fat-18m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	5.39e-05	196	92	5	2cd83176f2e8a9e6fa3c08cb33928a61e5fc43b6
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDK4 CSPG4 UGDH LOXL4 ITPR3	5.52e-05	197	92	5	8786125b669d5d0b15e12df0ade6b319f09f7333
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	EGF ANK2 PCDHGA7 AZGP1 HPS6	5.66e-05	198	92	5	62059185afdf66126a6fbc899ce611c47e7a0feb
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL20A1 AZGP1 CSPG4 PCDH15 UNC80	5.66e-05	198	92	5	02d0d8a212e09c0962ab1dae6a885d26d357f66a
ToppCell	facs-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGDH LRP1 SGCE HAS1 TNXB	5.66e-05	198	92	5	0dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell	facs-Trachea-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UGDH LRP1 SGCE HAS1 TNXB	5.66e-05	198	92	5	e85ae846e293687fd193f4d565525d8d3bd1faea
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PDK4 CSPG4 EMILIN3 LONRF2 TMEM200C	5.66e-05	198	92	5	7a0c4dbc8c99968d42af00a718f4fedc544599ec
ToppCell	368C-Fibroblasts-Fibroblast-D-\|368C / Donor, Lineage, Cell class and subclass (all cells)	ANK2 UGDH LRP1 SGCE TNXB	5.79e-05	199	92	5	5a425e7d11c5911ff5855c27a7f058a7ed7abbb0
ToppCell	368C-Fibroblasts-Fibroblast-D\|368C / Donor, Lineage, Cell class and subclass (all cells)	ANK2 UGDH LRP1 SGCE TNXB	5.79e-05	199	92	5	66545eb7f65e450b742628fd431956e13330a0d3
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	ANK2 SGCE HAS1 TNXB TMEM200C	5.79e-05	199	92	5	675f7c56b03a7918e2d9ca99440df6f27ad8e838
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ANK2 CSPG4 LRP1 EMILIN3 TNXB	5.79e-05	199	92	5	95d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CSPG4 PCDH15 LRP1 ADGRA1 UNC80	5.79e-05	199	92	5	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	ANK2 SGCE HAS1 TNXB TMEM200C	5.79e-05	199	92	5	97d74985018816754d11a55b9fb689690ecb1374
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ANK2 CSPG4 LRP1 HAS1 TNXB	5.93e-05	200	92	5	747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	COL20A1 CSPG4 PCDH15 MDGA2 UNC80	5.93e-05	200	92	5	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	COL20A1 CSPG4 PCDH15 MDGA2 UNC80	5.93e-05	200	92	5	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	COL20A1 CSPG4 PCDH15 MDGA2 UNC80	5.93e-05	200	92	5	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Biopsy_Other_PF-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ANK2 UGDH SGCE HAS1 TNXB	5.93e-05	200	92	5	0aa316b71f195ecf17ee897e307f8928a755a637
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ANK2 CSPG4 LRP1 HAS1 TNXB	5.93e-05	200	92	5	de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CSPG4 PCDH15 LRP1 MDGA2 ADGRA1	5.93e-05	200	92	5	ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	COL20A1 CSPG4 PCDH15 MDGA2 UNC80	5.93e-05	200	92	5	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANK2 HMCN1 PCDH15 LRP1 TNXB	5.93e-05	200	92	5	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	COL20A1 CSPG4 PCDH15 MDGA2 UNC80	5.93e-05	200	92	5	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	COL20A1 CSPG4 PCDH15 MDGA2 UNC80	5.93e-05	200	92	5	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	LPS-IL1RA-Epithelial_alveolar-Mes-Like-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CSPG4 DPYSL5 LOXL4 DNAH5	6.20e-05	103	92	4	eb9f008b5fb8a01df8ea4faf6e6aebc1a9db9bd3
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	EFNB3 ANK2 PCDHGA6 AZGP1	1.53e-04	130	92	4	3709d17044d48b120effd8ba4104ca81c49d7e19
ToppCell	COVID-19-kidney-Epithelial_(EC)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MAG PCDH15 MDGA2 FBN3	1.67e-04	133	92	4	a8abb6b54862123961ae6defbf251ee6e9575258
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac1_Htr1d\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ATG9B EFNB3 UGDH APOBR	1.97e-04	139	92	4	fe1657ef9aeda7c530dc7febcd3dcd0e1d5f8a48
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1\|Striatum / BrainAtlas - Mouse McCarroll V32	NLRP10 HAS1 PDE10A CDH15	2.38e-04	146	92	4	7b863f9bc63dc1afe015a18a70cd6ed0b71d1f09
ToppCell	IIH-CD8-exh_CD4\|IIH / Condition, Cell_class and T cell subcluster	CNNM3 EIF5A2 LOXL4 NCOA5	2.92e-04	154	92	4	a2f51a3c5455fe2483e438375ea856afce8262fe
ToppCell	human_hepatoblastoma-Tumor_cells-T7\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PITPNM1 MYD88 EIF5A2 PRX	3.54e-04	162	92	4	c6ace47daf32495b25793d39b72382978349597d
ToppCell	Mild-Lymphoid-NK-innate_T\|Mild / Condition, Lineage, Cell class and cell subclass	CNNM3 ATG9B MAP3K9 ZC3H11B	3.54e-04	162	92	4	bd218e41b2eadc3bba4c7ac3e34a014f6ad8b1bf
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CELSR1 PALM3 DNAH5 FBN3	3.54e-04	162	92	4	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PITPNM1 DPYSL5 LRP1 MDGA2	3.79e-04	165	92	4	cca3ba9d7d30404e3e683b8cfd500c348a4974b9
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	ANK2 LONRF2 DNAH5 RFPL2	3.79e-04	165	92	4	9795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBC1D10A CSPG4 LOXL4 FJX1	3.88e-04	166	92	4	37794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CELSR1 GPR27 NTF4 FJX1	3.88e-04	166	92	4	1f39c7507ac6881aa1a30f8be22f98a1837d926b
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBC1D10A CSPG4 LOXL4 FJX1	3.88e-04	166	92	4	81c546c6d847e49e662b81e71992ca0f7a99e890
Drug	3-nitrocoumarin	EGF PLCB2 PLCB3	7.03e-06	10	90	3	CID002799766
Drug	Delcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A	NCOA2 SLC17A5 SLC22A18AS EFNB3 HPS6 ZNF407 PML	1.24e-05	195	90	7	4737_DN
Drug	4,4'-bisphenol F	NCOA2 PLCB2 PLCB3 PDE10A ALOX12	1.28e-05	76	90	5	ctd:C008745
Drug	Melatonin [73-31-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A	PITPNM1 ARHGEF40 GPR27 PDK4 IQSEC2 PLCB3 ITPR3	1.37e-05	198	90	7	5393_UP
Drug	Paromomycin sulfate [1263-89-4]; Down 200; 5.6uM; HL60; HT_HG-U133A	USP5 ANK2 PDK4 AZGP1 CC2D1A PLCB3 PML	1.42e-05	199	90	7	3017_DN
Drug	1 mag	MAG EGF	1.55e-05	2	90	2	CID000124835
Disease	Sarcosine measurement	PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	6.85e-07	23	90	4	EFO_0021668
Disease	mental development measurement	PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	9.75e-07	25	90	4	EFO_0008230
Disease	childhood trauma measurement, alcohol consumption measurement	PCDHGA12 PCDHGA7 PCDHGA6 PCDHGA5 PCDHGA3	2.62e-06	71	90	5	EFO_0007878, EFO_0007979
Disease	colorectal cancer (is_marker_for)	MYD88 ERCC4 KDM5C AZGP1 EIF5A	1.22e-04	157	90	5	DOID:9256 (is_marker_for)
Disease	xeroderma pigmentosum (implicated_via_orthology)	ERCC4 DDB1	1.37e-04	6	90	2	DOID:0050427 (implicated_via_orthology)
Disease	Charcot-Marie-Tooth disease type 4	SBF2 PRX	7.02e-04	13	90	2	cv:C4082197
Disease	verbal-numerical reasoning measurement	NCOA2 ERCC4 LONRF2 FBN3	7.06e-04	131	90	4	EFO_0008394
Disease	Alzheimer's disease (implicated_via_orthology)	ANK2 LRP1 APLP2	7.13e-04	57	90	3	DOID:10652 (implicated_via_orthology)
Disease	stomach cancer (is_marker_for)	NCOA2 KDM5C SGCE ADAR	9.53e-04	142	90	4	DOID:10534 (is_marker_for)
Disease	acute kidney failure (is_marker_for)	EGF AZGP1	1.21e-03	17	90	2	DOID:3021 (is_marker_for)
Disease	Alcoholic Intoxication, Chronic	SLC17A5 EGF SGCE PDE10A CDH15	1.40e-03	268	90	5	C0001973
Disease	urate measurement	SLC22A18AS TBC1D10A SBF2 CSPG4 DPYSL5 RDH14 LRP1 EIF5A2 PLCB3	1.64e-03	895	90	9	EFO_0004531
Disease	colorectal carcinoma (is_implicated_in)	NCOA2 MYD88	2.04e-03	22	90	2	DOID:0080199 (is_implicated_in)
Disease	response to anticonvulsant	TDRD15 ANK2 LOXL4	2.26e-03	85	90	3	GO_0036277
Disease	hypertension	SBF2 ZC3H11B PLCB2 PLCB3 TNXB	2.52e-03	307	90	5	EFO_0000537

Protein segments in the cluster

Peptide	Gene	Start	Entry
EEGAGERELEGPGLL	ARHGEF40	466	Q8TER5
QDLEDGRLGLEVGRP	CSPG4	2116	Q6UVK1
EEQRRLATPEGGRGI	ADGRA1	216	Q86SQ6
AEGLPGQLGRDRLEV	SLC22A18AS	131	Q8N1D0
PRELLDVGRDGRLAG	CELSR1	61	Q9NYQ6
ERILELRPALEGLEG	FBN3	2721	Q75N90
SGDEEEEGPIVLGRR	DDX27	56	Q96GQ7
PVGEELLGRVVDALG	ATP5F1A	141	P25705
EVEGIGEALGPEELR	REC8	246	O95072
VDLRGREVEVLGEVP	NTF4	111	P34130
DLGLEPRELAERGVR	PCDHGA7	51	Q9Y5G6
DLGLEPQELAERGVR	PCDHGA5	51	Q9Y5G8
DLGLEPRELAERGVR	PCDHGA12	51	O60330
FREKGGEGPLVRLEE	ITPR3	526	Q14573
LLVEGLEGPEVAGRE	PALM3	356	A6NDB9
EREGGEEPLGIERKV	PALM3	446	A6NDB9
ISDRGGGVPLRIIDR	PDK4	291	Q16654
VEGEGLASRLIEVGP	ANK2	1021	Q01484
VGGLEEERESVGPLR	APLP2	671	Q06481
VGEGEEEELGRRGRA	FHIP1B	606	Q8N612
ELGVEARDGPGLRDR	PCDHGA6	316	Q9Y5G7
EPDRALVVIGGDGLR	KLHL33	206	A6NCF5
VRLAGGRIPEEGLLE	LOXL4	421	Q96JB6
GEPAVLGRLREDEGT	MAG	181	P20916
VLLDPDGREEATGGL	SBF2	891	Q86WG5
PLERLGAGVAGVEDI	RPS6KC1	1036	Q96S38
RGELEGLIPVDLAEL	NLRP10	46	Q86W26
EKRELLGRGPEDEIG	LRP1	4526	Q07954
GEVREDLKLPEGELG	EIF5A2	106	Q9GZV4
RGVDNGEDIPRDLLV	IQSEC2	916	Q5JU85
AGPGRGARRLLVLEE	GPR27	261	Q9NS67
DILGDERFPRGTGLE	PDE10A	166	Q9Y233
ILQERERGGPEEGVR	NCOA5	321	Q9HCD5
LGRDDVLLELGPSIE	MYD88	96	Q99836
GEVREDLRLPEGDLG	EIF5A	106	P63241
RLGALRPEELEELAG	LONRF2	86	Q1L5Z9
RPEELEELAGGLVRA	LONRF2	91	Q1L5Z9
QLRGILEGELEGIRG	GCAT	26	O75600
GEAELELQLRPARGE	ALOX12	31	P18054
EGIRGPGIEGDIAID	MDGA2	896	Q7Z553
ELTGREPGISILEDG	HMCN1	1306	Q96RW7
DLGLEPRELAERGVR	PCDHGA3	51	Q9Y5H0
IREVLGFGGPDARLE	PLCB3	86	Q01970
EDGRLRPLRDAGGEL	FJX1	261	Q86VR8
GEGGRILEIRTPEAV	PCDH15	1346	Q96QU1
LEILDGTRGTVDGPR	ADAR	1136	P55265
RERLIEEGVDVPEGL	EGF	546	P01133
EREVQVGRPEVLLDG	COL20A1	511	Q9P218
LEVLDGRRPTGGRLE	CC2D1A	771	Q6P1N0
ERCLIEGTIDGLEPG	CCS	111	O14618
VELLRREPGALGARG	ATG9B	466	Q674R7
EDPRVGAVGGDVRIL	HAS1	256	Q92839
GVERDLRGQVPGGER	MCRIP1	46	C9JLW8
LRGQVPGGERGLVEE	MCRIP1	51	C9JLW8
PGLFGERLERLEGDV	EMILIN3	176	Q9NT22
VLGEEGTRPEALELE	HPS6	611	Q86YV9
REAEPGELGIALRGG	EFNB3	286	Q15768
VGPLIVLRALEGLGE	SLC17A5	161	Q9NRA2
VDVGRLEVEDRDLPG	CDH15	276	P55291
RIGRPSETGIIGIID	DDB1	111	Q16531
ELLTGEVPFRGIDGL	MAP3K9	341	P80192
LSLGRPLLIEDVGEE	DNAH5	3641	Q8TE73
LDLGITGPEGIEISR	DPYSL5	206	Q9BPU6
LSERERIGELGAPEV	NKAP	131	Q8N5F7
LDIEPEGGERRRTEA	UVSSA	381	Q2YD98
GERGSQEIPRGELDL	TMEM200C	406	A6NKL6
VLLIDRGEELRVAGP	TDRD15	91	B5MCY1
LEGISELDIRTGGVP	TCAF2	221	A6NFQ2
EGLLEGPALARAEGV	PML	851	P29590
PGVSGVGELIVRELD	RDH14	101	Q9HBH5
QEVIRGEGILPDGGE	SGCE	286	O43556
GILGREEARTTPGRE	APOBR	276	Q0VD83
LRERVLELARGGGDP	CNNM3	286	Q8NE01
DGLEEIDRALGIPEL	NCOA2	1091	Q15596
IGGEGPKRIILEEVR	PIGA	261	P37287
VRDPLADGVEGLGRG	PITPNM1	606	O00562
DRVLIGGDETPEGQR	UGDH	176	O60701
EDAEGEGLLLIPGGR	ZBTB12	271	Q9Y330
EGQGIPREELDERIA	UNC80	2471	Q8N2C7
RGLPEGRGELRGLVV	TEX54	41	A0A1B0GVG6
GDQEEGGLRVRLPSV	PRX	1426	Q9BXM0
PERGGGELDLVVREL	TEDC1	351	Q86SX3
DRDGRPQVVRVGGEE	TNXB	2131	P22105
TPLRIVGGVDAEEGR	PRSS42P	76	Q7Z5A4
LIRLEGVEGRDPVGG	RFPL2	41	O75678
EGPEGVDGRVRELKD	PLCB2	971	Q00722
GEEPLVRLGLTETLG	ZC3H11B	271	A0A1B0GTU1
RAGEVQEPELRGDVL	AZGP1	241	P25311
RRGIDIEPVTLEVGD	ERCC4	701	Q92889
EVEGRAGLEEQGRPG	ZNF407	2001	Q9C0G0
REVVDEGLIPGDGLG	GTF3C1	1101	Q12789
GAEGALEEVPLEVLR	TBC1D10A	66	Q9BXI6
GIEGPLLASDVGRDR	SON	1751	P18583
IARDGLGGLPDIVRD	USP5	131	P45974
LEGLVAVGRDLPVGL	KDM5C	1051	P41229