Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainIPT

NFKB2 PKHD1L1

2.09e-0327472SM00429
DomainDEATH

ANK3 NFKB2

2.09e-0327472SM00005
DomainIPT

NFKB2 PKHD1L1

2.93e-0332472IPR002909
DomainDeath

ANK3 NFKB2

3.11e-0333472PF00531
DomainDeath_domain

ANK3 NFKB2

4.11e-0338472IPR000488
DomainDEATH_DOMAIN

ANK3 NFKB2

4.11e-0338472PS50017
Domainp53-like_TF_DNA-bd

NFKB2 MYRFL

7.87e-0353472IPR008967
DomainVWA

ITGA11 ITIH4

8.75e-0356472PF00092
Pubmed

Loss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin.

ESR1 VCL

1.94e-06249228266545
Pubmed

T cell-intrinsic function of the noncanonical NF-κB pathway in the regulation of GM-CSF expression and experimental autoimmune encephalomyelitis pathogenesis.

CSF2 NFKB2

5.83e-06349224899500
Pubmed

Periodic Remodeling in a Neural Circuit Governs Timing of Female Sexual Behavior.

GAD1 ESR1

5.83e-06349231735496
Pubmed

Estrogen receptor signaling promotes dendritic cell differentiation by increasing expression of the transcription factor IRF4.

CSF2 ESR1

1.16e-05449219880499
Pubmed

Genetic variations in the Hippo signaling pathway and breast cancer risk in African American women in the AMBER Consortium.

PTPN14 ESR1

1.16e-05449227485598
Pubmed

Disruption of the gene encoding SF-1 alters the distribution of hypothalamic neuronal phenotypes.

GAD1 ESR1

1.94e-05549210880989
Pubmed

Gamma-aminobutyric acidB receptors and the development of the ventromedial nucleus of the hypothalamus.

GAD1 ESR1

1.94e-05549212115679
Pubmed

Special relationship of gamma-aminobutyric acid to the ventromedial nucleus of the hypothalamus during embryonic development.

GAD1 ESR1

2.91e-05649210022198
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DIP2B CACNB3 ANK3 MAP4 DTNB TTC21B FRYL SRCIN1 ZNF236 UBLCP1

3.58e-051489491028611215
Pubmed

Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region.

SEPTIN8 CSF2

5.42e-0584929149945
Pubmed

Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.

ANK3 VCL

5.42e-05849228826662
Pubmed

GABA influences the development of the ventromedial nucleus of the hypothalamus.

GAD1 ESR1

5.42e-05849211745664
Pubmed

OCT-4: a novel estrogen receptor-α collaborator that promotes tamoxifen resistance in breast cancer cells.

ESR1 POU2F2

5.42e-05849227065334
Pubmed

BioID-based proteomic analysis of the Bid interactome identifies novel proteins involved in cell-cycle-dependent apoptotic priming.

MAP4 MCCC1 SON

6.55e-055549333067418
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

EEFSEC SEPTIN8 MAP4 MCCC1 GEN1 VCL SON

6.61e-0572449736232890
Pubmed

Selective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the mouse mammary tumor virus promoter.

ESR1 POU2F2

6.96e-05949210480874
Pubmed

Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment.

GAD1 ANK3

6.96e-05949215479642
Pubmed

Distinct nuclear and cytoplasmic assemblies and interactomes of the mammalian CTLH E3 ligase complex.

BRIX1 GSE1 MAP4 SDCBP

9.18e-0516749435833506
Pubmed

Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.

GAD1 MAP4 ITIH4

9.37e-056249319367581
Pubmed

Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin.

ANK3 DTNB

1.06e-041149210995443
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

DOCK3 GSE1 ANK3 MAP4 SON

1.54e-0436149526167880
Pubmed

Genetic mapping of the mouse genes encoding the voltage-sensitive calcium channel subunits.

GAD1 CACNB3

1.75e-04144927490102
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

DOCK3 SEPTIN8 GAD1 DMXL2 ANK3 MAP4 SRCIN1 MCCC1

1.77e-04113949836417873
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DIP2B PTPN14 MAP4 FRYL MCCC1 GEN1 DYRK2

1.93e-0486149736931259
Pubmed

A conserved regulatory logic controls temporal identity in mouse neural progenitors.

GAD1 VSX1

2.02e-041549225654255
Pubmed

Identification of 40 genes on a 1-Mb contig around the IL-4 cytokine family gene cluster on mouse chromosome 11.

SEPTIN8 CSF2

2.30e-041649210704283
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SEPTIN8 DIP2B FRYL

2.56e-048749312465718
Pubmed

Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.

GAD1 ANK3

2.93e-041849237321992
Pubmed

Proteomic analysis of ubiquitination substrates reveals a CTLH E3 ligase complex-dependent regulation of glycolysis.

GSE1 MAP4 SDCBP

3.42e-049649334383978
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DMXL2 FRYL ABCA8

3.86e-0410049310048485
Pubmed

An estrogen-responsive module in the ventromedial hypothalamus selectively drives sex-specific activity in females.

GAD1 ESR1

4.01e-042149225543145
Pubmed

An unappreciated role for RNA surveillance.

MAP4 DTNB SON

4.09e-0410249314759258
Pubmed

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.

CACNB3 ANK3 ITIH4

4.09e-0410249321926972
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

DIP2B DMXL2 ANK3 ITIH4

4.35e-0425149427507650
Pubmed

Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons.

GAD1 ESR1

4.83e-042349229795232
Pubmed

The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation.

GAD1 ESR1

4.83e-042349225505333
Pubmed

Genome-wide association study identifies five new schizophrenia loci.

ANK3 ITIH4

4.83e-042349221926974
Pubmed

Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.

ESR1 VCL

4.83e-042349223152823
Pubmed

Gsg1, Trnp1, and Tmem215 Mark Subpopulations of Bipolar Interneurons in the Mouse Retina.

GAD1 VSX1

5.71e-042549228199486
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

BRIX1 MCCC1 SDCBP VCL ATP6V0A2

5.89e-0448449531995728
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK3 DMXL2 TTC21B MEAK7 ABCA8

6.40e-0449349515368895
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

DMXL2 GSE1 SDCBP VCL SON

6.64e-0449749523414517
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

DMXL2 CACNB3 ANK3 SRCIN1

6.64e-0428149428706196
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

SEPTIN8 ATR MAP4 DTNB GOSR1 MEAK7 ATP6V0A2

6.77e-04106149733845483
Pubmed

Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain.

GAD1 ESR1

8.25e-043049229972793
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ESR1 NFKB2 POU2F2 ZNF236 PKHD1L1 NUFIP1

9.22e-0480849620412781
Pubmed

A global genomic transcriptional code associated with CNS-expressed genes.

PTPN14 GSE1 C19orf12 MCCC1

1.05e-0331849416919269
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

DIP2B ANK3 MAP4 FRYL SRCIN1

1.11e-0355849535063084
Pubmed

Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex.

DMXL2 SRCIN1

1.12e-033549237758766
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

ANK3 MAP4 SRCIN1 SDCBP VCL

1.18e-0356549525468996
Pubmed

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.

DMXL2 DTNB FRYL

1.18e-0314749329576527
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

DOCK3 GAD1 RIN3 MAP4

1.19e-0332949417474147
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

DIP2B PTPN14 SLC15A1 DTNB MEAK7

1.21e-0356949530639242
Pubmed

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.

GAD1 ATR ESR1 VCL

1.22e-0333149420634891
Pubmed

Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.

ANK3 MCCC1 VCL SON

1.22e-0333149429199018
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

BRIX1 MEAK7 SDCBP SON

1.23e-0333249425693804
Pubmed

Ion channel expression in the developing enteric nervous system.

CACNB3 ANK3

1.25e-033749225798587
InteractionSNAP25 interactions

GAD1 GOSR1 SRCIN1 SDCBP NUFIP1

8.14e-06116485int:SNAP25
InteractionSEPTIN3 interactions

SEPTIN8 ESR1 SDCBP NUFIP1

1.83e-0566484int:SEPTIN3
InteractionTRIP6 interactions

GAD1 RIN3 PTPN14 GSE1 ESR1 VCL SON

2.07e-05358487int:TRIP6
InteractionCTBP2 interactions

CACNB3 ATR DTNB ESR1 NFKB2 VSX1 SDCBP

2.56e-05370487int:CTBP2
Cytoband12q15

MYRFL DYRK2

5.42e-043249212q15
Cytoband16q24.1

GSE1 MEAK7

5.77e-043349216q24.1
CytobandEnsembl 112 genes in cytogenetic band chr12q15

MYRFL DYRK2

1.66e-0356492chr12q15
GeneFamilyPRD class homeoboxes and pseudogenes

VSX1 LEUTX

6.57e-0392242521
CoexpressionGSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_UP

CACNB3 SLC15A1 DTNB NFKB2 ATP6V0A2

2.87e-05191495M8671
CoexpressionGSE21033_CTRL_VS_POLYIC_STIM_DC_1H_DN

CSF2 SLC15A1 NFKB2 VSX1 DYRK2

3.40e-05198495M7716
CoexpressionGSE3691_IFN_PRODUCING_KILLER_DC_VS_CONVENTIONAL_DC_SPLEEN_UP

DIP2B MAP4 ZNF236 MEAK7 MAP4K2

3.57e-05200495M6363
CoexpressionGSE19923_HEB_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN

DIP2B NFKB2 SDCBP VCL ATP6V0A2

3.57e-05200495M7271
CoexpressionGSE2770_UNTREATED_VS_ACT_CD4_TCELL_6H_DN

GAD1 DMXL2 PTPN14 TTC21B FRYL

3.57e-05200495M6018
ToppCellURO-Lymphocyte-T_NK-dnT|URO / Disease, Lineage and Cell Type

GSE1 MCCC1 MEAK7 UBLCP1 CXorf65

1.69e-06182495f2b1c524301d0f2d1b69c46f3653fd53c21c3aa0
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

DIP2B ATR GOSR1 FRYL SON

2.26e-06193495abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 ESR1 NFKB2 ABCA8 VCL

2.31e-0619449590efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 ESR1 NFKB2 ABCA8 VCL

2.31e-06194495df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellCV-Severe-6|CV / Virus stimulation, Condition and Cluster

RIN3 CSF2 C19orf12 POU2F2 VCL

2.37e-0619549569095c6ce2a7e763afa543c10d5710e0c3dda769
ToppCellMacroglial-Oligodendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

DIP2B ANK3 FRYL SRCIN1 ABCA8

2.69e-062004954dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCellSepsis-URO-Lymphocyte-T/NK-dn_T|URO / Disease, condition lineage and cell class

GSE1 MCCC1 MEAK7 UBLCP1 CXorf65

2.69e-0620049504ea6381b93a5d8bbeda4d71c788d7fbac6d40bc
ToppCellMacroglial-Oligodendrocytes-OPALIN---|Macroglial / cells hierarchy compared to all cells using T-Statistic

DIP2B ANK3 FRYL SRCIN1 ABCA8

2.69e-062004951314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCellMacroglial-Oligodendrocytes-OPALIN-|Macroglial / cells hierarchy compared to all cells using T-Statistic

DIP2B ANK3 FRYL SRCIN1 ABCA8

2.69e-062004958b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCellMacroglial-Oligodendrocytes-OPALIN----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

DIP2B ANK3 FRYL SRCIN1 ABCA8

2.69e-06200495272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCellMacroglial-Oligodendrocytes-OPALIN--|Macroglial / cells hierarchy compared to all cells using T-Statistic

DIP2B ANK3 FRYL SRCIN1 ABCA8

2.69e-0620049526b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCellMacroglial-Oligodendrocytes-OPALIN|Macroglial / cells hierarchy compared to all cells using T-Statistic

DIP2B ANK3 FRYL SRCIN1 ABCA8

2.69e-062004955f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 ESR1 ABCA8 VCL

4.76e-0518249444764676ed3f51ba171ce63f669390392fa50a43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 ESR1 ABCA8 VCL

4.76e-05182494d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCelldroplet-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANK3 SLC15A1 SRCIN1 ITIH4

5.63e-05190494a51405f8466fc6d4087873137472619b2e84c1da
ToppCelldroplet-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANK3 SLC15A1 SRCIN1 ITIH4

5.63e-05190494059beca1c92181b8ba4dcd6fc71ff7530d83d0de
ToppCelldroplet-Lung-18m-Epithelial-alveolar_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANK3 SLC15A1 SRCIN1 ITIH4

5.74e-05191494caed913e7ede9f8ae3af273d1ecf375de6c5e813
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 GSE1 ESR1 ABCA8

5.86e-051924949333aba0d04203ccccad78d82bf6359922f810a7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 ESR1 ABCA8 VCL

6.22e-05195494783bfa8110161cbd6def50ce849cae676c39c458
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 ESR1 ABCA8 VCL

6.22e-05195494cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 ESR1 ABCA8 VCL

6.35e-051964942b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 ESR1 ABCA8 VCL

6.47e-0519749409946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA11 ESR1 ABCA8 VCL

6.47e-0519749480e153790cef37b743e22a7370ff5b3a6abf147d
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4|GI_small-bowel / Manually curated celltypes from each tissue

CSF2 ANK3 NFKB2 POU2F2

6.60e-051984946333e46cd1ccf5841ce15aea98a4b2f5e3ae4675
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ITGA11 ESR1 MAP4K2 ABCA8

6.60e-051984947d2fe57e0f9311ac1e6854402ebc154306eb1ba5
ToppCellLPS_IL1RA-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

GAD1 ITGA11 PKHD1L1 VCL

6.86e-05200494326cae37cacd94b423a6ac8873ea56c5abaf0a0b
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

DOCK3 GAD1 ANK3 SRCIN1

6.86e-05200494bad32a95b759fad509401b07bc96a56687c2a592
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal|5w / Sample Type, Dataset, Time_group, and Cell type.

GAD1 ANK3 MAP4 POU2F2

6.86e-052004949b5753726c17dda98d7384a60f26a5eaf4f6c4d6
DrugPicotamide monohydrate [80530-63-8]; Down 200; 10.2uM; PC3; HT_HG-U133A

SEPTIN8 MAP4 GOSR1 FRYL MAP4K2 DYRK2

3.53e-061974862070_DN
DrugNP-O-Su

ESR1 NFKB2

1.30e-053482CID000126530
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A

CACNB3 MAP4 DTNB NFKB2 POU2F2

5.16e-051924853114_UP
DrugTolazamide [1156-19-0]; Up 200; 12.8uM; MCF7; HT_HG-U133A

DMXL2 CSF2 MAP4 ESR1 ZNF236

5.29e-051934852842_UP
DrugPodophyllotoxin [518-28-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A

DOCK3 NFKB2 POU2F2 MAP4K2 VCL

5.29e-051934856103_UP
DrugMethocarbamol [532-03-6]; Down 200; 16.6uM; PC3; HT_HG-U133A

GAD1 CACNB3 MAP4 NFKB2 MAP4K2

5.42e-051944852111_DN
Druglithium aluminum hydride

CSF2 ESR1 NFKB2 POU2F2 ITIH4 ATP6V0A2

5.49e-05320486CID000028112
DrugNaloxone hydrochloride [357-08-4]; Down 200; 11uM; HL60; HG-U133A

ATR MAP4 FRYL SON DYRK2

5.56e-051954852006_DN
Drugrapamycin, Streptomyces hygroscepicus; Up 200; 0.1uM; MCF7; HT_HG-U133A

DOCK3 RIN3 ANK3 ESR1 ZNF236

5.70e-051964855975_UP
DrugSelegiline hydrochloride [14611-52-0]; Up 200; 17.8uM; HL60; HT_HG-U133A

ANK3 SLC15A1 MAP4 ESR1 POU2F2

5.83e-051974852465_UP
DrugSparteine (-) [90-39-1]; Up 200; 17uM; MCF7; HT_HG-U133A

GAD1 RIN3 CSF2 NFKB2 VCL

5.83e-051974854391_UP
DrugTrapidil [15421-84-8]; Down 200; 19.4uM; MCF7; HT_HG-U133A

GAD1 PTPN14 MAP4 ESR1 ZNF236

5.98e-051984856515_DN
DrugProglumide [6620-60-6]; Up 200; 12uM; PC3; HT_HG-U133A

SLC15A1 MAP4 ESR1 POU2F2 VSX1

6.12e-051994854337_UP
DrugScopoletin [92-61-5]; Up 200; 20.8uM; HL60; HT_HG-U133A

ANK3 SLC15A1 MAP4 POU2F2 VSX1

6.27e-052004853131_UP
DrugPNU-0230031 [267429-39-0]; Up 200; 1uM; PC3; HT_HG-U133A

RIN3 CSF2 ANK3 ESR1 POU2F2

6.27e-052004853735_UP
DrugAlfadolone acetate [23930-37-2]; Up 200; 10.2uM; HL60; HT_HG-U133A

SEPTIN8 ANK3 MAP4 POU2F2 MAP4K2

6.27e-052004853127_UP
DiseaseParkinsonism (implicated_via_orthology)

CSF2 ESR1 NFKB2

1.34e-0529473DOID:0080855 (implicated_via_orthology)
Diseasesexual dimorphism measurement

DOCK3 DIP2B CSF2 ESR1 C19orf12 GOSR1 FRYL ABCA8 ATP6V0A2

5.33e-051106479EFO_0021796
Diseaseeosinophil count

DOCK3 EEFSEC SEPTIN8 DIP2B RIN3 CSF2 GSE1 ATR POU2F2 ITIH4

9.66e-0514884710EFO_0004842
Diseaseestrogen-receptor negative breast cancer

RIN3 ESR1 C19orf12

2.01e-0471473EFO_1000650
DiseaseNeoplasm of uncertain or unknown behavior of ovary

ATR ESR1

9.81e-0429472C0496920
Diseasebipolar disorder (is_implicated_in)

GAD1 ANK3

9.81e-0429472DOID:3312 (is_implicated_in)
DiseaseIGF-1 measurement

DOCK3 ITGA11 DTNB ESR1 NUFIP1

1.05e-03488475EFO_0004627
DiseaseOvarian Carcinoma

ATR ESR1

1.05e-0330472C0029925
Diseaseresting heart rate, chronic obstructive pulmonary disease

EEFSEC RIN3

1.05e-0330472EFO_0000341, EFO_0004351
Diseasehip bone mineral density

PTPN14 ESR1 TTC21B

1.07e-03126473EFO_0007702
Diseaseovarian neoplasm

ATR ESR1 C19orf12

1.28e-03134473C0919267
Diseasemacrophage inflammatory protein 1b measurement

DOCK3 ANK3 MAP4

1.34e-03136473EFO_0008219
DiseaseMalignant neoplasm of ovary

ATR ESR1 C19orf12

1.37e-03137473C1140680

Protein segments in the cluster

PeptideGeneStartEntry
DAIKTLHMAMSLPGM

TTC21B

581

Q7Z4L5
LHMAMSLPGMKRIGA

TTC21B

586

Q7Z4L5
MERLKSHKPATMTIM

C19orf12

1

Q9NSK7
RSKSLENHPKSMTMM

CAGE1

751

Q8TC20
TGKMKMLFLMKPNHA

CXorf65

46

A6NEN9
SRGKSQMKHLTVQMM

CACNB3

306

P54284
MVGAKPKTTMHIMIY

DNM1P46

76

Q6ZS02
MKGMSHEPKSPSLGM

GSE1

1

Q14687
LRMLMPHSKADTKMD

BRIX1

81

Q8TDN6
THMNILAPTVMMISK

DMXL2

601

Q8TDJ6
VMPGLKMTMDKTGLL

ITIH4

821

Q14624
HLHPMRALMLMSKSS

MAP4K2

216

Q12851
MTSQRGMLKSIHSKM

GOSR1

191

O95249
IMMGLKTTDMAPSKE

MAP4

241

P27816
KIKALMMESGTTMVG

GAD1

541

Q99259
MTMTLHTKASGMALL

ESR1

1

P03372
SLFKHIVPMMRSESM

FRYL

916

O94915
MNKMHTISVPYSVMK

DIP2B

576

Q9P265
MKVMGTIMHPSDSRA

MYRFL

441

Q96LU7
MVHSSMGAPEIRMSK

POU2F2

1

P09086
HGMMMKITIPIATRS

ITGA11

1001

Q9UKX5
KSLMIMKMISATEGP

MEAK7

106

Q6P9B6
ALNSLMSLMKLMGPK

ATR

1151

Q13535
MSLMKLMGPKHVSSV

ATR

1156

Q13535
LMGPKHVSSVRVKMM

ATR

1161

Q13535
SLTKLKGPLTMMASH

CSF2

86

P04141
SIKMTHRHSPMNLMG

DOCK3

1661

Q8IZD9
SVKAMLATMCGGKML

DTNB

131

O60941
PIKMGISASTMTMKK

ANK3

3721

Q12955
VMIAMKMEHTIKSPK

MCCC1

676

Q96RQ3
VKKMMGSVMKPHLRN

GEN1

41

Q17RS7
LKMRVSKPFGMLMLS

FMR1NB

61

Q8N0W7
RMAPSIMKSLMDHTI

SDCBP

281

O00560
TSLKKMAVGMVLASM

SLC15A1

356

P46059
KSMEGMGKVKATPMT

DYRK2

141

Q92630
VPMMEKILQKFTSMH

RIN3

736

Q8TB24
RGMEAMTLKSLHLPM

PTPN14

651

Q15678
LMSVTGKNMKMHSFI

ABCA8

201

O94911
MHKKSMGMIRKPGSE

VSX1

271

Q9NZR4
KVKSMQMFHMPITSA

EEFSEC

266

P57772
MAHTMPKLKAFSMSS

TAS1R1

371

Q7RTX1
GKMKGMSRHSQMAKI

NUFIP1

276

Q9UHK0
AHMFPQKLTMGMLKS

SRCIN1

211

Q9C0H9
TKNLGPGMTKMAKMI

VCL

161

P18206
HQPGMSLSSSKVMMT

SEPTIN8

436

Q92599
TFPVMMHHKTKGSAM

PKHD1L1

1976

Q86WI1
LGALKLKPNTKIMMM

UBLCP1

61

Q8WVY7
GSLTRHMATHMSMKP

ZNF236

1036

Q9UL36
PMILESSIMSSHVMK

SON

1471

P18583
KMKMSVILGIIHMTF

ATP6V0A2

551

Q9Y487
MHPSLATMGKLASKL

LEUTX

31

A8MZ59
LGVLHVTKKNMMGTM

NFKB2

136

Q00653