Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC9C2 RYR3 CUL5 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G SLC4A5	6.49e-08	465	114	15	GO:0046873
GeneOntologyMolecularFunction	delayed rectifier potassium channel activity	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1	4.91e-07	28	114	5	GO:0005251
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC9C2 SLC36A2 RYR3 CUL5 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G SLC4A5	5.49e-07	627	114	16	GO:0022890
GeneOntologyMolecularFunction	monoatomic cation channel activity	RYR3 CUL5 KCNA2 KCNA3 KCNA6 KCNA7 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G	6.27e-07	343	114	12	GO:0005261
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC7A13 ABCC11 SLC44A4 SLC9C2 SLC36A2 RYR3 CUL5 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 SLCO4C1 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G SLC4A5 ABCG5 SLC2A11	7.58e-07	1180	114	22	GO:0022857
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC9C2 SLC36A2 RYR3 CUL5 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G SLC4A5	1.17e-06	664	114	16	GO:0008324
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	ABCC11 SLC9C2 SLC36A2 RYR3 CUL5 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G SLC4A5	1.40e-06	758	114	17	GO:0015318
GeneOntologyMolecularFunction	voltage-gated potassium channel activity	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2	1.94e-06	102	114	7	GO:0005249
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2 CACNA1G	2.61e-06	152	114	8	GO:0022843
GeneOntologyMolecularFunction	transporter activity	SLC7A13 ABCC11 SLC44A4 SLC9C2 SLC36A2 RYR3 CUL5 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 SLCO4C1 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G SLC4A5 ABCG5 SLC2A11	3.25e-06	1289	114	22	GO:0005215
GeneOntologyMolecularFunction	gated channel activity	RYR3 KCNA2 KCNA3 KCNA6 KCNA7 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G	3.38e-06	334	114	11	GO:0022836
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	SLC9C2 KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2	5.25e-06	167	114	8	GO:0015079
GeneOntologyMolecularFunction	potassium channel activity	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2	8.79e-06	128	114	7	GO:0005267
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2 CACNA1G	9.87e-06	182	114	8	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2 CACNA1G	1.07e-05	184	114	8	GO:0022832
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC9C2 SLC36A2 RYR3 CUL5 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G SLC4A5	1.12e-05	793	114	16	GO:0015075
GeneOntologyMolecularFunction	monoatomic ion channel activity	RYR3 CUL5 KCNA2 KCNA3 KCNA6 KCNA7 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G	1.25e-05	459	114	12	GO:0005216
GeneOntologyMolecularFunction	channel activity	RYR3 CUL5 KCNA2 KCNA3 KCNA6 KCNA7 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G	4.67e-05	525	114	12	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	RYR3 CUL5 KCNA2 KCNA3 KCNA6 KCNA7 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G	4.75e-05	526	114	12	GO:0022803
GeneOntologyMolecularFunction	calmodulin binding	MYO1D SPTBN1 UBR4 RYR3 EGFR KCNQ1 KCNQ2	3.56e-04	230	114	7	GO:0005516
GeneOntologyMolecularFunction	outward rectifier potassium channel activity	KCNA2 KCNA3 KCNQ1	4.80e-04	27	114	3	GO:0015271
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC7A13 SLC44A4 SLC9C2 SLC36A2 SLC13A4 SLCO4C1 SLC4A5	1.56e-03	296	114	7	GO:0015291
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC7A13 ABCC11 SLC44A4 SLC9C2 SLC36A2 SLC13A4 SLCO4C1 SLC4A5 ABCG5	1.66e-03	477	114	9	GO:0022804
GeneOntologyBiologicalProcess	action potential	KCNA2 KCNA3 KCNA6 KCNA7 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G	1.24e-07	201	110	10	GO:0001508
GeneOntologyBiologicalProcess	early endosome to recycling endosome transport	DNAJC13 MYO1D SORL1	5.09e-06	7	110	3	GO:0061502
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	SLC9C2 SLC36A2 RYR3 CUL5 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 P2RX4 ASPH SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G SLC4A5	7.56e-06	922	110	17	GO:0098662
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	SLC9C2 SLC36A2 RYR3 CUL5 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 P2RX4 ASPH SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G SLC4A5	1.00e-05	942	110	17	GO:0098655
GeneOntologyBiologicalProcess	monoatomic ion transport	HFE ABCC11 NMUR1 SLC9C2 SLC36A2 RYR3 CUL5 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 SLCO4C1 P2RX4 ASPH SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G SLC4A5	1.05e-05	1374	110	21	GO:0006811
GeneOntologyBiologicalProcess	metal ion transport	HFE SLC9C2 RYR3 CUL5 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 P2RX4 ASPH SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G SLC4A5	2.16e-05	1000	110	17	GO:0030001
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	ABCC11 SLC9C2 SLC36A2 RYR3 CUL5 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 P2RX4 ASPH SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G SLC4A5	2.40e-05	1115	110	18	GO:0034220
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	SLC9C2 SLC36A2 RYR3 CUL5 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 P2RX4 ASPH SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G SLC4A5	2.67e-05	1017	110	17	GO:0098660
GeneOntologyBiologicalProcess	potassium ion transmembrane transport	SLC9C2 KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2	3.47e-05	232	110	8	GO:0071805
GeneOntologyBiologicalProcess	monoatomic cation transport	HFE SLC9C2 SLC36A2 RYR3 CUL5 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 P2RX4 ASPH SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G SLC4A5	3.90e-05	1157	110	18	GO:0006812
GeneOntologyBiologicalProcess	protein localization to plasma membrane	TRARG1 SPTBN1 SIRT6 EFR3A EGFR EFR3B MACF1 HECTD1 SORL1	6.03e-05	324	110	9	GO:0072659
GeneOntologyBiologicalProcess	potassium ion transport	SLC9C2 KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2	1.06e-04	272	110	8	GO:0006813
GeneOntologyBiologicalProcess	sodium ion transport	SLC9C2 SLC13A4 P2RX4 SCN7A KCNQ1 KCNQ2 CACNA1G SLC4A5	1.14e-04	275	110	8	GO:0006814
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	SLC9C2 SLC13A4 SCN7A KCNQ1 KCNQ2 CACNA1G SLC4A5	1.27e-04	208	110	7	GO:0035725
GeneOntologyBiologicalProcess	regulation of early endosome to recycling endosome transport	DNAJC13 SORL1	1.68e-04	4	110	2	GO:1902954
GeneOntologyBiologicalProcess	regulation of membrane potential	CDKN2A KCNA2 KCNA3 KCNA6 KCNA7 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G	1.99e-04	559	110	11	GO:0042391
GeneOntologyBiologicalProcess	lipid digestion	ASAH2 LPCAT3 ABCG5	2.75e-04	24	110	3	GO:0044241
GeneOntologyCellularComponent	cation channel complex	RYR3 KCNA2 KCNA3 KCNA6 KCNA7 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G	6.52e-07	235	114	10	GO:0034703
GeneOntologyCellularComponent	voltage-gated potassium channel complex	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2	6.61e-07	91	114	7	GO:0008076
GeneOntologyCellularComponent	potassium channel complex	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2	1.64e-06	104	114	7	GO:0034705
GeneOntologyCellularComponent	transmembrane transporter complex	COX7A2 RYR3 KCNA2 KCNA3 KCNA6 KCNA7 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G ABCG5	2.89e-05	523	114	12	GO:1902495
GeneOntologyCellularComponent	monoatomic ion channel complex	RYR3 KCNA2 KCNA3 KCNA6 KCNA7 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G	4.26e-05	378	114	10	GO:0034702
GeneOntologyCellularComponent	transporter complex	COX7A2 RYR3 KCNA2 KCNA3 KCNA6 KCNA7 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G ABCG5	4.71e-05	550	114	12	GO:1990351
Domain	VG_K_chnl	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2	9.23e-10	33	113	7	IPR028325
Domain	Ion_trans_dom	RYR3 KCNA2 KCNA3 KCNA6 KCNA7 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G	1.76e-09	114	113	10	IPR005821
Domain	Ion_trans	RYR3 KCNA2 KCNA3 KCNA6 KCNA7 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G	1.76e-09	114	113	10	PF00520
Domain	Channel_four-helix_dom	SLC9C2 KCNA2 KCNA3 KCNA6 KCNA7 SCN7A KCNS2 CACNA1G	1.80e-09	57	113	8	IPR027359
Domain	-	SLC9C2 KCNA2 KCNA3 KCNA6 KCNA7 SCN7A KCNS2 CACNA1G	1.80e-09	57	113	8	1.20.120.350
Domain	K_chnl_volt-dep_Kv1	KCNA2 KCNA3 KCNA6 KCNA7	8.73e-08	8	113	4	IPR003972
Domain	K_chnl_volt-dep_Kv	KCNA2 KCNA3 KCNA6 KCNA7 KCNS2	5.38e-07	27	113	5	IPR003968
Domain	BTB_2	KCNA2 KCNA3 KCNA6 KCNA7 KCNS2	1.69e-05	53	113	5	PF02214
Domain	T1-type_BTB	KCNA2 KCNA3 KCNA6 KCNA7 KCNS2	1.69e-05	53	113	5	IPR003131
Domain	ARM-type_fold	DNAJC13 UBR4 HEATR5A CUL7 TEX10 RYR3 EFR3A ELMO3 EFR3B HECTD1	4.04e-05	339	113	10	IPR016024
Domain	Fumarylacetoacetase_C-rel	FAHD2B FAHD2A	2.16e-04	4	113	2	IPR011234
Domain	FAA_hydrolase	FAHD2B FAHD2A	2.16e-04	4	113	2	PF01557
Domain	-	FAHD2B FAHD2A	2.16e-04	4	113	2	3.90.850.10
Domain	ARM-like	DNAJC13 HEATR5A CUL7 TEX10 EFR3A ELMO3 EFR3B HECTD1	2.38e-04	270	113	8	IPR011989
Domain	K_chnl_volt-dep_KCNQ_C	KCNQ1 KCNQ2	3.59e-04	5	113	2	IPR013821
Domain	K_chnl_volt-dep_KCNQ	KCNQ1 KCNQ2	3.59e-04	5	113	2	IPR003937
Domain	KCNQ_channel	KCNQ1 KCNQ2	3.59e-04	5	113	2	PF03520
Domain	-	DNAJC13 HEATR5A CUL7 TEX10 EFR3A EFR3B HECTD1	4.06e-04	222	113	7	1.25.10.10
Domain	APC_su10/DOC_dom	CUL7 ZZEF1	7.47e-04	7	113	2	IPR004939
Domain	DOC	CUL7 ZZEF1	7.47e-04	7	113	2	PS51284
Domain	ANAPC10	CUL7 ZZEF1	7.47e-04	7	113	2	PF03256
Domain	APC10	CUL7 ZZEF1	7.47e-04	7	113	2	SM01337
Domain	Cullin_neddylation_domain	CUL7 CUL5	9.92e-04	8	113	2	IPR019559
Domain	Cullin_Nedd8	CUL7 CUL5	9.92e-04	8	113	2	PF10557
Domain	Cullin_Nedd8	CUL7 CUL5	9.92e-04	8	113	2	SM00884
Domain	Cullin_homology	CUL7 CUL5	1.27e-03	9	113	2	IPR016158
Domain	Cullin	CUL7 CUL5	1.58e-03	10	113	2	PF00888
Domain	CULLIN_2	CUL7 CUL5	1.58e-03	10	113	2	PS50069
Domain	Cullin_N	CUL7 CUL5	1.58e-03	10	113	2	IPR001373
Domain	CULLIN_1	CUL7 CUL5	1.58e-03	10	113	2	PS01256
Pathway	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2	6.09e-09	43	85	7	M1056
Pathway	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNS2	1.53e-07	41	85	6	MM14546
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2	2.80e-06	103	85	7	M1073
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNS2	2.72e-05	98	85	6	MM14545
Pathway	REACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_PATHWAY	MED14 IFNA7 IFNA8 CUL5 EGFR TLR3	8.48e-05	120	85	6	M48233
Pathway	KEGG_MEDICUS_REFERENCE_TLR3_IRF7_SIGNALING_PATHWAY	IFNA7 IFNA8 TLR3	1.91e-04	19	85	3	M47450
Pathway	REACTOME_RSV_HOST_INTERACTIONS	MED14 IFNA7 IFNA8 CUL5 TLR3	3.10e-04	98	85	5	M48247
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	KCNA2 KCNA3 KCNA6 KCNA7 P2RX4 SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G	3.58e-11	139	114	10	16985003
Pubmed	International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2	5.75e-11	40	114	7	16382104
Pubmed	Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7.	KCNA2 KCNA3 KCNA6 KCNA7	1.36e-08	9	114	4	9488722
Pubmed	Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow.	KCNA2 KCNA3 KCNA6	3.41e-07	5	114	3	21233214
Pubmed	Physical mapping of potassium channel gene clusters on mouse chromosomes three and six.	KCNA2 KCNA3 KCNA6	6.81e-07	6	114	3	9286706
Pubmed	Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly.	KCNA2 KCNA3 KCNA6	6.81e-07	6	114	3	14686897
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	GALNS UBR4 CUL7 KMT2C PTPN13 PCNX4 MACF1 HECTD1 BCL2L13	1.24e-06	322	114	9	26514267
Pubmed	KCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epithelium.	KCNA3 KCNA6 KCNQ1	1.90e-06	8	114	3	21859894
Pubmed	Exclusion of two candidate genes, Spnb-2 and Dcd, for the wobbler spinal muscular atrophy gene on proximal mouse chromosome 11.	SPTBN1 EGFR IL3	2.84e-06	9	114	3	8199405
Pubmed	Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome.	KCNA2 KCNA3 KCNA6 KCNA7	3.22e-06	31	114	4	8034307
Pubmed	Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells.	KCNA2 KCNA3 KCNA6	4.05e-06	10	114	3	1383027
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RHBDD1 DNAJC13 RNF213 VTI1A SLC35F5 CUL5 KMT2C PTPN13 EGFR PCNX4 LPCAT3 ASPH MACF1 TMEM143 HECTD1 SLC4A5 SLC2A11	7.26e-06	1489	114	17	28611215
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	MYO1D UBR4 CUL7 DHX30 PTPN13 MAGED4 GEMIN4 SLC2A11	9.48e-06	313	114	8	38270169
Pubmed	Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors.	CDKN2A EGFR	1.07e-05	2	114	2	16672372
Pubmed	RME-8 regulates trafficking of the epidermal growth factor receptor.	DNAJC13 EGFR	1.07e-05	2	114	2	18307993
Pubmed	Murine pancreatic tumor cell line TD2 bears the characteristic pattern of genetic changes with two independently amplified gene loci.	CDKN2A EGFR	1.07e-05	2	114	2	14555993
Pubmed	Expression of p16 protein and epidermal growth factor receptor in patients with adenocarcinoma of the uterine cervix: an immunohistochemical analysis.	CDKN2A EGFR	1.07e-05	2	114	2	20405295
Pubmed	New strategy for suppressing the growth of lung cancer cells harboring mutations in the ATP-binding region of EGFR by targeting the molecular motor MYO1D.	MYO1D EGFR	1.07e-05	2	114	2	34459138
Pubmed	Stearoyl-CoA desaturase activity modulates the activation of epidermal growth factor receptor in human lung cancer cells.	EGFR SCD	1.07e-05	2	114	2	22946088
Pubmed	The diagnostic utility of PRAME and p16 in distinguishing nodal nevi from nodal metastatic melanoma.	CDKN2A PRAME	1.07e-05	2	114	2	32825968
Pubmed	Nuclear epidermal growth factor receptor and p16 expression in head and neck squamous cell carcinoma.	CDKN2A EGFR	1.07e-05	2	114	2	23086695
Pubmed	Differential expression of murine CGI-105 gene in 3T3-L1 cells by adrenocorticotropic hormones.	FAHD2B FAHD2A	1.07e-05	2	114	2	15774318
Pubmed	Expression and chromosomal localization of a lymphocyte K+ channel gene.	KCNA2 KCNA3	1.07e-05	2	114	2	2251283
Pubmed	EGFR-driven up-regulation of decoy receptor 3 in keratinocytes contributes to the pathogenesis of psoriasis.	TNFRSF6B EGFR	1.07e-05	2	114	2	23707413
Pubmed	MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer.	CDKN2A KMT2C	1.07e-05	2	114	2	37261974
Pubmed	RHBDD1 upregulates EGFR via the AP-1 pathway in colorectal cancer.	RHBDD1 EGFR	1.07e-05	2	114	2	28445956
Pubmed	Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response.	IFNA7 IFNA8 TLR3	1.22e-05	14	114	3	20566717
Pubmed	Frontline Science: Estrogen-related receptor γ increases poly(I:C)-mediated type I IFN expression in mouse macrophages.	IFNA7 IFNA8 TLR3	1.52e-05	15	114	3	33615540
Pubmed	Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness.	KCNA2 KCNA3 KCNA6	1.86e-05	16	114	3	28283561
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NR2C1 TAF1C SPTBN1 UBR4 NARS1 TTC27 RYR3 DHX30 BEX3 PTPN13 KCNQ2 MACF1 CERCAM CHPF HECTD1	2.04e-05	1285	114	15	35914814
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	DNAJC13 MYO1D SPTBN1 NARS1 ABCC11 SLC44A4 SLC36A2 PARP4 PTPN13 SLCO4C1 P2RX4 GEMIN4 SORL1	2.98e-05	1016	114	13	19056867
Pubmed	Expression of cyclin-dependent kinase inhibitor 2A 16, tumour protein 53 and epidermal growth factor receptor in salivary gland carcinomas is not associated with oncogenic virus infection.	CDKN2A EGFR	3.19e-05	3	114	2	25012870
Pubmed	[Expression of epidermal growth factor receptor Ki67 and p16 in human middle ear cholesteatoma].	CDKN2A EGFR	3.19e-05	3	114	2	19157151
Pubmed	Recurrent copy number alterations involving EGFR, CDKN2A, and CCND1 in oral premalignant lesions.	CDKN2A EGFR	3.19e-05	3	114	2	35488777
Pubmed	Squamous Cell Carcinoma of the Vulva: A Subclassification of 97 Cases by Clinicopathologic, Immunohistochemical, and Molecular Features (p16, p53, and EGFR).	CDKN2A EGFR	3.19e-05	3	114	2	26171917
Pubmed	p14(ARF) inhibits the growth of lung adenocarcinoma cells harbouring an EGFR L858R mutation by activating a STAT3-dependent pro-apoptotic signalling pathway.	CDKN2A EGFR	3.19e-05	3	114	2	22450744
Pubmed	Development of Resistance to EGFR-Targeted Therapy in Malignant Glioma Can Occur through EGFR-Dependent and -Independent Mechanisms.	CDKN2A EGFR	3.19e-05	3	114	2	25808866
Pubmed	HPV-related Sinonasal Carcinoma: Clinicopathologic Features, Diagnostic Utility of p16 and Rb Immunohistochemistry, and EGFR Copy Number Alteration.	CDKN2A EGFR	3.19e-05	3	114	2	31743130
Pubmed	Nuclear trafficking of EGFR by Vps34 represses Arf expression to promote lung tumor cell survival.	CDKN2A EGFR	3.19e-05	3	114	2	26686095
Pubmed	A universal metabolite repair enzyme removes a strong inhibitor of the TCA cycle.	FAHD2B FAHD2A	3.19e-05	3	114	2	38287013
Pubmed	Seizures and reduced life span in mice lacking the potassium channel subunit Kv1.2, but hypoexcitability and enlarged Kv1 currents in auditory neurons.	KCNA2 KCNA6	3.19e-05	3	114	2	17634333
Pubmed	Differential NF1, p16, and EGFR patterns by interphase cytogenetics (FISH) in malignant peripheral nerve sheath tumor (MPNST) and morphologically similar spindle cell neoplasms.	CDKN2A EGFR	3.19e-05	3	114	2	12152785
Pubmed	Chronic activation of wild-type epidermal growth factor receptor and loss of Cdkn2a cause mouse glioblastoma formation.	CDKN2A EGFR	3.19e-05	3	114	2	21987724
Pubmed	Chimeric mouse tumor models reveal differences in pathway activation between ERBB family- and KRAS-dependent lung adenocarcinomas.	CDKN2A EGFR	3.19e-05	3	114	2	20023657
Pubmed	Functional interaction of Fas-associated phosphatase-1 (FAP-1) with p75(NTR) and their effect on NF-kappaB activation.	BEX3 PTPN13	3.19e-05	3	114	2	10544233
Pubmed	Correlations between prognosis and regional biomarker profiles in head and neck squamous cell carcinomas.	CDKN2A EGFR	3.19e-05	3	114	2	25547827
Pubmed	Immunohistochemical assessment of p16, COX-2 and EGFR in HPV-positive cervical squamous intraepithelial lesions.	CDKN2A EGFR	3.19e-05	3	114	2	22203921
Pubmed	EFR3s are palmitoylated plasma membrane proteins that control responsiveness to G-protein-coupled receptors.	EFR3A EFR3B	3.19e-05	3	114	2	25380825
Pubmed	Rhomboid domain containing 1 promotes the growth of non-small cell lung cancer through the activation of EGFR and regulation of the BIK-mediated apoptosis.	RHBDD1 EGFR	3.19e-05	3	114	2	34962825
Pubmed	EGFRvIII-Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival.	TNFRSF12A EGFR	3.19e-05	3	114	2	29724813
Pubmed	EGFR modulates monounsaturated fatty acid synthesis through phosphorylation of SCD1 in lung cancer.	EGFR SCD	3.19e-05	3	114	2	28724430
Pubmed	Cigarette smoke augments MUC5AC production via the TLR3-EGFR pathway in airway epithelial cells.	EGFR TLR3	3.19e-05	3	114	2	26100173
Pubmed	Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6.	SIRT6 EGFR	3.19e-05	3	114	2	26657850
Pubmed	Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated with Upregulation of Cyclin D1 and Downregulation of p16.	CDKN2A EGFR	3.19e-05	3	114	2	27702388
Pubmed	miR-145-5p restrained cell growth, invasion, migration and tumorigenesis via modulating RHBDD1 in colorectal cancer via the EGFR-associated signaling pathway.	RHBDD1 EGFR	3.19e-05	3	114	2	31693935
Pubmed	Impaired reciprocal regulation between SIRT6 and TGF-β signaling in fatty liver.	SPTBN1 SIRT6	3.19e-05	3	114	2	35506565
Pubmed	Cloning, sequence and chromosomal localization of MK6, a murine potassium channel gene.	KCNA2 KCNA6	3.19e-05	3	114	2	1285906
Pubmed	The induction of H3K9 methylation by PIWIL4 at the p16Ink4a locus.	CDKN2A PIWIL1	3.19e-05	3	114	2	17544373
Pubmed	Clinical spectrum of voltage-gated potassium channel autoimmunity.	KCNA2 KCNA6	3.19e-05	3	114	2	18474843
Pubmed	KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis.	CDKN2A KMT2C	3.19e-05	3	114	2	35354467
Pubmed	Rhinovirus-induced major airway mucin production involves a novel TLR3-EGFR-dependent pathway.	EGFR TLR3	3.19e-05	3	114	2	18978302
Pubmed	A family of three mouse potassium channel genes with intronless coding regions.	KCNA2 KCNA3	3.19e-05	3	114	2	2305265
Pubmed	The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins.	UBR4 EGFR	3.19e-05	3	114	2	30157281
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	SPTBN1 KCNA2 KCNA3 KCNA6 KCNQ2 MACF1	4.91e-05	197	114	6	36604605
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYO1D SPTBN1 UBR4 NARS1 CUL7 TEX10 DHX30 GEMIN4 MACF1 HECTD1	6.01e-05	653	114	10	22586326
Pubmed	A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon.	KCNA2 KCNQ2	6.36e-05	4	114	2	16525039
Pubmed	The role of the small intestine in modulating metabolism and inflammation in atherosclerosis and cancer.	SCD LPCAT3	6.36e-05	4	114	2	31356236
Pubmed	KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.	KCNA2 KCNA3	6.36e-05	4	114	2	12944270
Pubmed	A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly.	KCNQ1 KCNQ2	6.36e-05	4	114	2	12524525
Pubmed	The expression of EGFR, cerbB2, p16, and p53 and their relationship with conventional parameters in squamous cell carcinoma of the larynx.	CDKN2A EGFR	6.36e-05	4	114	2	25558642
Pubmed	LKB1, TP16, EGFR, and KRAS somatic mutations in lung adenocarcinomas from a Chiba Prefecture, Japan cohort.	CDKN2A EGFR	6.36e-05	4	114	2	22460425
Pubmed	Correlation of EGFR Del 19 with Fn14/JAK/STAT signaling molecules in non-small cell lung cancer.	TNFRSF12A EGFR	6.36e-05	4	114	2	27350337
Pubmed	Brain beta spectrin isoform 235 (Spnb-2) maps to mouse chromosome 11.	SPTBN1 EGFR	6.36e-05	4	114	2	1638088
Pubmed	EGFR-AKT-Smad signaling promotes formation of glioma stem-like cells and tumor angiogenesis by ID3-driven cytokine induction.	CDKN2A EGFR	6.36e-05	4	114	2	21975932
Pubmed	Combined detection of p53, p16, Rb, and EGFR mutations in lung cancer by suspension microarray.	CDKN2A EGFR	6.36e-05	4	114	2	20082263
Pubmed	Genetic mapping of the mouse interleukin 3 gene to chromosome 11.	EGFR IL3	6.36e-05	4	114	2	3494779
Pubmed	Role of epidermal growth factor receptor signaling in RAS-driven melanoma.	CDKN2A EGFR	6.36e-05	4	114	2	15870287
Pubmed	Combined targeting of TGF-β, EGFR and HER2 suppresses lymphangiogenesis and metastasis in a pancreatic cancer model.	CDKN2A EGFR	6.36e-05	4	114	2	27267807
Pubmed	Inhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptors.	KCNQ1 KCNQ2	6.36e-05	4	114	2	10713961
Pubmed	Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis.	CDKN2A EGFR	6.36e-05	4	114	2	19196966
Pubmed	Comprehensive Genomic Profiling of Advanced Penile Carcinoma Suggests a High Frequency of Clinically Relevant Genomic Alterations.	CDKN2A EGFR	6.36e-05	4	114	2	26670666
Pubmed	Using next-generation sequencing to determine potential molecularly guided therapy options for patients with resectable pancreatic adenocarcinoma.	CDKN2A EGFR	6.36e-05	4	114	2	26754455
Pubmed	Inhibition of EGFR induces a c-MET-driven stem cell population in glioblastoma.	CDKN2A EGFR	6.36e-05	4	114	2	24115218
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	MYO1D RNF213 KMT2C KCNA3 TLR3 SORL1	6.64e-05	208	114	6	33230847
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	DNAJC13 DHX30 ASPH KCNQ2 MACF1	6.65e-05	128	114	5	30995482
Pubmed	The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation.	IFNA7 IFNA8 TLR3	8.44e-05	26	114	3	38744293
Pubmed	Chromosomal mapping in the mouse of eight K(+)-channel genes representing the four Shaker-like subfamilies Shaker, Shab, Shaw, and Shal.	KCNA2 KCNA3 KCNA6	8.44e-05	26	114	3	7905852
Pubmed	Stage-specific expression of the Kit receptor and its ligand (KL) during male gametogenesis in the mouse: a Kit-KL interaction critical for meiosis.	CDKN2A EGFR	1.06e-04	5	114	2	9778516
Pubmed	Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells.	CDKN2A EGFR	1.06e-04	5	114	2	26592448
Pubmed	The contribution of Kv7 channels to pregnant mouse and human myometrial contractility.	KCNQ1 KCNQ2	1.06e-04	5	114	2	20132415
Pubmed	Patterns of EGFR, HER2, TP53, and KRAS mutations of p14arf expression in non-small cell lung cancers in relation to smoking history.	CDKN2A EGFR	1.06e-04	5	114	2	17575133
Pubmed	The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane.	EFR3A EFR3B	1.06e-04	5	114	2	26571211
Pubmed	Genome-wide association study of type 2 diabetes in a sample from Mexico City and a meta-analysis of a Mexican-American sample from Starr County, Texas.	CDKN2A KCNQ1	1.06e-04	5	114	2	21573907
Pubmed	K+ current diversity is produced by an extended gene family conserved in Drosophila and mouse.	KCNA2 KCNA3	1.06e-04	5	114	2	2333511
Pubmed	Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice.	SPTBN1 EGFR	1.06e-04	5	114	2	7565694
Pubmed	T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.	SPTBN1 CACNA1G	1.06e-04	5	114	2	29720258
Pubmed	Subunit composition of Kv1 channels in human CNS.	KCNA2 KCNA3	1.06e-04	5	114	2	10428084
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	DNAJC13 MRPS18B RANBP3 SPTBN1 UBR4 COX7A2 TBC1D17 DHX30 EFR3A PTPN13 EGFR SCD ASPH EFR3B MACF1	1.06e-04	1487	114	15	33957083
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	RYR3 GIPR EGFR KCNQ1 IL3	1.12e-04	143	114	5	20424473
Pubmed	Transgenic mice in the study of cytokine function.	IFNA7 IFNA8 IL3	1.18e-04	29	114	3	7507352
Interaction	KCNA3 interactions	MYO1D SPTBN1 NARS1 RNF213 EFR3A KMT2C PTPN13 KCNA2 KCNA3 KCNA6 EGFR TLR3 EFR3B GEMIN4 MACF1 SORL1	1.24e-05	871	106	16	int:KCNA3
Interaction	RAPSN interactions	UBR4 ZZEF1 MACF1 UBE2Z	1.34e-05	28	106	4	int:RAPSN
Interaction	ZBBX interactions	FAT3 ZZEF1 TBC1D17 SORL1	2.04e-05	31	106	4	int:ZBBX
GeneFamily	Potassium voltage-gated channels	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2 KCNS2	1.14e-09	40	92	7	274
GeneFamily	Solute carriers	SLC7A13 SLC44A4 SLC9C2 SLC36A2 SLC35F5 SLC13A4 SLCO4C1 SLC4A5 SLC2A11	1.82e-04	395	92	9	752
GeneFamily	Cullins	CUL7 CUL5	7.03e-04	8	92	2	1032
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FAT3 TTC27 SLC36A2 KCNA7 ASPH EFR3B SORL1	2.85e-07	170	114	7	ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	WSCD1 FAT3 BEX3 EGFR ASPH KCNQ2 CHPF	7.95e-07	198	114	7	81c4c5377d0901ee9594424f08b0e4101686c850
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FAT3 SLC36A2 SLC13A4 RANBP3L MAMDC2 MACF1	5.79e-06	174	114	6	3c47d069bd836599a8d40eae485c23d4d3487517
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FAT3 PCDHB11 SLC36A2 KCNA2 MAMDC2 CERCAM	7.49e-06	182	114	6	ba066ff9029cc052b76e2330ec168cb2e9b7e498
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	FAT3 SPTBN1 MAMDC2 SCN7A MACF1 SORL1	9.57e-06	190	114	6	71e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	MYO1D FAT3 RANBP3L MAMDC2 SCN7A MACF1	1.05e-05	193	114	6	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FAT3 SLC36A2 RANBP3L MAMDC2 CERCAM CHPF	1.08e-05	194	114	6	292ce9021678534c9eedb367b9772a9d976208a8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC44A4 SLC35F5 PARP4 SLCO4C1 EGFR MAMDC2	1.08e-05	194	114	6	8ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCell	AT2_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	MMP28 TNFRSF12A BEX3 PTPN13 SLCO4C1 EGFR	1.11e-05	195	114	6	b0cea3f4e59635913d243612f2e8cf4c7b34e726
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FAT3 SPTBN1 MAMDC2 SCN7A MACF1 SORL1	1.14e-05	196	114	6	6730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MMP28 GPR160 PTPN13 SLCO4C1 SCD TTC39A	1.14e-05	196	114	6	82b117be41f2e7d677a42d2a5198726eeccb16d0
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FAT3 SPTBN1 MAMDC2 SCN7A MACF1 SORL1	1.14e-05	196	114	6	21dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell	cellseq-Epithelial\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KLK11 SLC44A4 BEX3 PTPN13 EGFR ASPH	1.28e-05	200	114	6	e4204c4b864346f47d76b0f0faae96f04fed5082
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Mesenchymal\|1m / Sample Type, Dataset, Time_group, and Cell type.	COX7A2 SLC35F5 BEX3 SLC13A4 SCD CHPF	1.28e-05	200	114	6	12359a6cf2c24cd373d4db3cab4d8ee2fb4a508f
ToppCell	Mild/Remission-B_naive-5\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	GPR20 PIWIL1 ARHGEF15 KCNA7 SORL1	3.25e-05	142	114	5	fc5fc2d2b4b976358b8ce762c1f440b20db84103
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FAT3 PIWIL1 RYR3 EFR3A SORL1	3.83e-05	147	114	5	8f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCell	Mild/Remission-B_naive-5\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	GPR20 PIWIL1 ARHGEF15 KCNA7 SORL1	3.96e-05	148	114	5	8b60f9843505660b3c9d5c7792976f902be4b94c
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SLC36A2 PTPN13 KCNA2 KCNA3 MAMDC2	4.79e-05	154	114	5	44d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLK11 PCDHB11 BEX3 EGFR CERCAM	6.83e-05	166	114	5	1f39c7507ac6881aa1a30f8be22f98a1837d926b
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 PCDHB11 PTPN13 MAMDC2 CACNA1G	7.03e-05	167	114	5	e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCell	facs-Skin-Anagen-24m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLK11 GPR160 PTPN13 SCD LRIT1	7.03e-05	167	114	5	02c89069dcd0e87f7502e32b14e7cbd3cab81a09
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNS SLC7A13 MED14 SLCO4C1 SCD	7.23e-05	168	114	5	35ce3b2b9c9997d4c101da5949c7271d6a6b8f12
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6\|TCGA-Liver / Sample_Type by Project: Shred V9	GPR20 NMUR1 MAMDC2 SCN7A KCNS2	7.43e-05	169	114	5	e992530776cab922d0360b275fb9cb8bd0017b06
ToppCell	normal-na-Lymphocytic_B-B_plasma-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	RHBDD1 MYO1D GPR160 GIPR CHPF	7.64e-05	170	114	5	c5b87974dfddf9780051f7f5693eeeb0c606a3fe
ToppCell	facs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 TRARG1 FAT3 CACNA1G EGFLAM	8.53e-05	174	114	5	197686570cec6d96a92e77e6409325d3bfe6f991
ToppCell	facs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 TRARG1 FAT3 CACNA1G EGFLAM	8.53e-05	174	114	5	2eee7b5471672b439f95eba11494c2adf8cb7006
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FAT3 SLC36A2 KCNA3 SCN7A MACF1	8.76e-05	175	114	5	282f09bbdfa70d93b3f66591dcfb84c5ee0268c7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D FAT3 PARP4 EGFR CERCAM	9.24e-05	177	114	5	da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FAT3 SLC36A2 MAMDC2 CERCAM EGFLAM	9.49e-05	178	114	5	e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 TRARG1 MMP28 MAMDC2 EGFLAM	9.75e-05	179	114	5	b7281160c84dd053a2981c9c76ea6cc6d2592cd5
ToppCell	droplet-Bladder-nan-24m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 KCNA2 SLCO4C1 SCD SCN7A	9.75e-05	179	114	5	dfd9d29281510d32f1a2e8336d2e58ef496cfd1d
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ELMO3 SLCO4C1 KCNQ1 TTLL10 SLC4A5	9.75e-05	179	114	5	ca70a5518c5a5392e088c103e0cb44aa084f5332
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ELMO3 SLCO4C1 KCNQ1 TTLL10 SLC4A5	9.75e-05	179	114	5	c451b074b04eb5d6c575c6abaedda579c6744bbf
ToppCell	E18.5-samps\|World / Age Group, Lineage, Cell class and subclass	GIPR PTPN13 SLCO4C1 SCD SLC4A5	1.05e-04	182	114	5	9649f15858d1ede73e068afc59df3ac367b49687
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP28 PTPN13 KCNA2 KCNA6 SCN7A	1.05e-04	182	114	5	6fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 SLC35F5 PARP4 EGFR CERCAM	1.08e-04	183	114	5	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	GPR160 PTPN13 SLCO4C1 SCD TTC39A	1.11e-04	184	114	5	0ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D FAT3 PARP4 EGFR CERCAM	1.11e-04	184	114	5	da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO1D PTPN13 EGFR ASPH TTC39A	1.11e-04	184	114	5	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	GPR160 PTPN13 SLCO4C1 SCD TTC39A	1.11e-04	184	114	5	2a8338e94937686a148b5433515700ca0f674058
ToppCell	BAL-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	INTS10 BEX3 MAMDC2 GEMIN4 SLC2A11	1.14e-04	185	114	5	e867ed55ab0df018f14bca824da09d36d83e12f9
ToppCell	normal_Lung-B_lymphocytes-MALT_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	CDKN2A MYO1D KCNA3 CERCAM CHPF	1.17e-04	186	114	5	f4d72463c5f287da6436287eda0a349b4185841e
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC44A4 SLC9C2 GIPR PTPN13	1.18e-04	98	114	4	ffe21b3681fdeaf4a8447bd2b13772d03cdd45aa
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MMP28 BEX3 PTPN13 SLCO4C1 SCD	1.20e-04	187	114	5	7c44cec1c26ca5907a495f2d7e633410e2e9728f
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	FAT3 RANBP3L MAMDC2 SCN7A MACF1	1.20e-04	187	114	5	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 TRARG1 FAT3 MAMDC2 EGFLAM	1.20e-04	187	114	5	dba4924d914a7dcd4901142684ba920c2404860b
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 TRARG1 FAT3 MAMDC2 EGFLAM	1.20e-04	187	114	5	9688141beef4f62613d7a810c5872ccb9afc1a71
ToppCell	368C-Epithelial_cells\|368C / Donor, Lineage, Cell class and subclass (all cells)	MMP28 SLC44A4 GPR160 SCD TTC39A	1.29e-04	190	114	5	459811e88d3001816c2d89034e0921c24918c17f
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPN13 SCD MAMDC2 SCN7A TTC39A	1.32e-04	191	114	5	f00d6824bd138b192a996e9f7de57b235bb24c18
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC36A2 EGFR MAMDC2 CERCAM CHPF	1.32e-04	191	114	5	997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FAT3 RANBP3L MAMDC2 SCN7A MACF1	1.32e-04	191	114	5	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 ARHGEF15 TNFRSF12A SCN7A EGFLAM	1.35e-04	192	114	5	be75783d9578974b662e1cb13bd3442a921fd50a
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FAT3 RANBP3L MAMDC2 SCN7A MACF1	1.35e-04	192	114	5	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 ARHGEF15 TNFRSF12A SCN7A EGFLAM	1.35e-04	192	114	5	4fc98f30f8e738816cd93101fbe8ac40889e302a
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 EGFR CERCAM CHPF SORL1	1.35e-04	192	114	5	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	MYO1D FAT3 MAMDC2 SCN7A MACF1	1.35e-04	192	114	5	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 TRARG1 KCNA2 MAMDC2 EGFLAM	1.39e-04	193	114	5	1043b28503bfaa0d5a82ec358bc86cbde73ea8f2
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC35F5 PARP4 SLCO4C1 EGFR ABCG5	1.39e-04	193	114	5	ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 TRARG1 KCNA2 MAMDC2 EGFLAM	1.39e-04	193	114	5	0266a4fdf436d83ec1d9392abba8c6ec5166970a
ToppCell	cellseq2-Epithelial-Epithelial_Alveolar-AT2-AT2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TTC27 PTPN13 SLCO4C1 SUOX SCD	1.42e-04	194	114	5	df835578d86a49ae5af5632152fbab9548c0a448
ToppCell	cellseq2-Epithelial-Epithelial_Alveolar\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TTC27 PTPN13 SLCO4C1 SUOX SCD	1.42e-04	194	114	5	0715f2d55f4a6d2edda1b3dc52f12d25ce59eb10
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FAT3 SLC36A2 RANBP3L MAMDC2 CERCAM	1.42e-04	194	114	5	811b382ec3da06a6bda7360abc8b633f96b2019e
ToppCell	cellseq2-Epithelial-Epithelial_Alveolar-AT2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TTC27 PTPN13 SLCO4C1 SUOX SCD	1.42e-04	194	114	5	a4f7cd507eba40985d82635bbae28c7f5703f883
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GPR160 BEX3 PTPN13 SLCO4C1 SCD	1.45e-04	195	114	5	6617abca0009ad3d8731f515f91ab275f9ea4c40
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GPR160 BEX3 PTPN13 SLCO4C1 SCD	1.45e-04	195	114	5	6867f9c56ea27a17c8c4099aae0d79903c3748a5
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GPR160 BEX3 PTPN13 SLCO4C1 SCD	1.45e-04	195	114	5	fc0ae145a2118df7cbbc9ac4ca9dc12d26c087c4
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GPR160 BEX3 PTPN13 SLCO4C1 SCD	1.45e-04	195	114	5	3e24570def013d5b0b1ef1d7a5ced7dfd922590b
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GPR160 BEX3 PTPN13 SLCO4C1 SCD	1.45e-04	195	114	5	955a0a7244cd7eaf006a39e1bd03333baf6f30a4
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GPR160 BEX3 PTPN13 SLCO4C1 SCD	1.45e-04	195	114	5	37aa6e4123d37de4de42ca68d3020f2a7686ce02
ToppCell	3'-Parenchyma_lung-Epithelial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GPR160 BEX3 PTPN13 SLCO4C1 SCD	1.45e-04	195	114	5	eec187c087e432417bc346c5d3ead72f58bf3215
ToppCell	NS-moderate-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KLK11 BEX3 PTPN13 ASPH SORL1	1.49e-04	196	114	5	5d5f3c3e9052b7cdca442e39e73b16ca27a16657
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 GPR160 PTPN13 KCNQ1 SORL1	1.49e-04	196	114	5	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	ASK440-Epithelial-Type_2\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	BEX3 PTPN13 SLCO4C1 SCD ASPH	1.49e-04	196	114	5	754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT3 RANBP3L MAMDC2 SCN7A MACF1	1.49e-04	196	114	5	9737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MMP28 GPR160 BEX3 SLCO4C1 SCD	1.49e-04	196	114	5	b1abecc0aafc09ca70a5fde624f2a998c4aa3341
ToppCell	cellseq-Epithelial-Epithelial_Alveolar\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GPR160 BEX3 PTPN13 SLCO4C1 SCD	1.49e-04	196	114	5	a7cbe66ebd8931ef2b8ff26a42afce0ad1c48f17
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MMP28 GPR160 BEX3 SLCO4C1 SCD	1.49e-04	196	114	5	9d267dd293fde05f04febc0a9d15776c5b782a1c
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 EGFR ASPH CERCAM CHPF	1.49e-04	196	114	5	2029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT3 RANBP3L MAMDC2 SCN7A MACF1	1.49e-04	196	114	5	cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FAT3 SLC36A2 RANBP3L MAMDC2 CERCAM	1.49e-04	196	114	5	d5ed41fa111750e6b363c04cccc40a47dd774852
ToppCell	368C-Fibroblasts-Fibroblast-G\|368C / Donor, Lineage, Cell class and subclass (all cells)	FAT3 SPTBN1 MAMDC2 SCN7A MACF1	1.53e-04	197	114	5	156155c2f0c1a2461e45803da578af18ee221660
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FAT3 SLC36A2 RANBP3L MAMDC2 CHPF	1.53e-04	197	114	5	2f72fd9a5b6d62c24a95ed2246194ea7458c0f12
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2-AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COX7A2 PTPN13 TTC39A CHPF SLC2A11	1.53e-04	197	114	5	ad6f047d003c08413264f39a30ba0f7639a257cd
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-B-Plasmablast\|ICU-NoSEP / Disease, condition lineage and cell class	FAHD2B MYO1D KCNA2 KCNA3 CHPF	1.53e-04	197	114	5	8f35f9741086a38f0e594dce0547b575946f52bb
ToppCell	368C-Fibroblasts-Fibroblast-G-\|368C / Donor, Lineage, Cell class and subclass (all cells)	FAT3 SPTBN1 MAMDC2 SCN7A MACF1	1.53e-04	197	114	5	d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCell	5'-Adult-Distal_Rectal-Epithelial-mature_enterocytic-Colonocyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MMP28 COX7A2 SLC44A4 GIPR TTC39A	1.53e-04	197	114	5	82e83b4e4f54f9aa3a4a7bbf48b6dd603adeb69b
ToppCell	5'-Adult-Distal_Rectal-Epithelial-mature_enterocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MMP28 COX7A2 SLC44A4 GIPR TTC39A	1.53e-04	197	114	5	8f894a4f0d34289f19d227788466b9fb4be15d54
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT3 RANBP3L MAMDC2 SCN7A MACF1	1.53e-04	197	114	5	13896ec65ccda0b928c91d41112dc01b480036b7
ToppCell	AT2_cells\|World / lung cells shred on cell class, cell subclass, sample id	GPR160 BEX3 PTPN13 SLCO4C1 SCD	1.56e-04	198	114	5	92c569c3b8a9fca2d4682cbf77ee8149bcc0a80a
ToppCell	AT2_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	GPR160 PTPN13 SLCO4C1 EGFR SCD	1.56e-04	198	114	5	893036558a9ad86b57f9e735df35812e9d18739e
ToppCell	distal-1-Epithelial-Club\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KLK11 SLC44A4 TNFRSF12A BEX3 PTPN13	1.60e-04	199	114	5	8f0a72a95d0310ef2324c6975495c294b5a47cc8
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FAT3 SLC36A2 MAMDC2 CERCAM CHPF	1.60e-04	199	114	5	d65ee89d5c7e8ed693d58e6a6de09565840e11c5
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	SPTBN1 ARHGEF15 BEX3 MACF1 EGFLAM	1.60e-04	199	114	5	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell	NS-control-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PTPN13 SLCO4C1 EGFR ASPH SORL1	1.60e-04	199	114	5	32bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCell	tumor_Lung-Epithelial_cells-tS2\|tumor_Lung / Location, Cell class and cell subclass	CDKN2A SLC44A4 TNFRSF12A EGFR ASPH	1.60e-04	199	114	5	28ec59e01061287fb0892491790b316e2b93e232
ToppCell	tumor_Lung-Epithelial_cells\|tumor_Lung / Location, Cell class and cell subclass	SLC44A4 BEX3 PTPN13 EGFR ASPH	1.60e-04	199	114	5	56b3f6c8b561d60780d91daf6b44a9dcf616e599
ToppCell	Biopsy_Control_(H.)-Epithelial-AT2\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	MMP28 GPR160 PTPN13 SLCO4C1 SCD	1.60e-04	199	114	5	5323d49d3be980605b3e609b7f03bddba6e50e8a
ToppCell	control-Epithelial-Secretory\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PTPN13 SLCO4C1 EGFR ASPH SORL1	1.60e-04	199	114	5	3d01f90ffd271ca00129192787e4921bdca7e01e
ToppCell	control-Epithelial-Secretory\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PTPN13 SLCO4C1 EGFR ASPH SORL1	1.60e-04	199	114	5	262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FAT3 SLC36A2 MAMDC2 CERCAM CHPF	1.60e-04	199	114	5	bf138cc692df727e087d140c014149ee5da00d9d
Drug	pyraclofos	KCNA2 KCNA3 KCNA6 KCNA7 SCN7A KCNQ1 KCNS2 CACNA1G	5.77e-08	106	113	8	CID000093460
Drug	AC1Q646P	TNFRSF6B KCNA2 KCNA3 KCNA6 KCNQ1 KCNQ2	1.19e-07	47	113	6	CID000005673
Drug	verapamil	CDKN2A SIRT6 RYR3 KCNA2 KCNA3 KCNA6 KCNA7 EGFR SCN7A KCNQ1 KCNQ2 KCNS2 CACNA1G	9.83e-07	490	113	13	CID000002520
Drug	clofilium	KCNA2 KCNA3 KCNA6 KCNA7 KCNQ1 KCNQ2	1.84e-06	74	113	6	CID000002798
Drug	Quipazine dimaleate salt [4774-24-7]; Up 200; 9uM; MCF7; HT_HG-U133A	HFE WSCD1 TAF1C TNFRSF6B SIRT6 ZZEF1 EGFR TTC39A	6.42e-06	197	113	8	2782_UP
Drug	E 4031	KCNA2 KCNA3 KCNA6 KCNQ1 KCNQ2	7.18e-06	54	113	5	CID000003184
Drug	sodium	FAHD2B SLC7A13 FAHD2A SIRT6 SLC36A2 RYR3 KCNA2 SLC13A4 KCNA3 KCNA6 P2RX4 SCN7A KCNQ1 IL3 SLC4A5 SLC2A11	1.72e-05	944	113	16	CID000000923
Drug	flecainide	RYR3 KCNA2 KCNA6 SCN7A KCNQ1	2.76e-05	71	113	5	CID000003355
Drug	sotalol	KCNA2 KCNA3 KCNA6 KCNQ1 KCNQ2	3.16e-05	73	113	5	CID000005253
Drug	2nq6	CCKBR GIPR EGFR	3.28e-05	13	113	3	CID011809364
Disease	epilepsy (implicated_via_orthology)	COX7A2 KCNA2 SLC13A4 KCNA3 KCNA6 KCNA7 SCN7A	1.99e-06	163	105	7	DOID:1826 (implicated_via_orthology)
Disease	Human papillomavirus infectious disease (is_marker_for)	CDKN2A EGFR TLR3	5.16e-06	10	105	3	DOID:11166 (is_marker_for)
Disease	Carcinoma, Granular Cell	CDKN2A VTI1A KMT2C EGFR KCNQ1	6.08e-05	116	105	5	C0205644
Disease	Adenocarcinoma, Tubular	CDKN2A VTI1A KMT2C EGFR KCNQ1	6.08e-05	116	105	5	C0205645
Disease	Adenocarcinoma, Oxyphilic	CDKN2A VTI1A KMT2C EGFR KCNQ1	6.08e-05	116	105	5	C0205642
Disease	Carcinoma, Cribriform	CDKN2A VTI1A KMT2C EGFR KCNQ1	6.08e-05	116	105	5	C0205643
Disease	Adenocarcinoma, Basal Cell	CDKN2A VTI1A KMT2C EGFR KCNQ1	6.08e-05	116	105	5	C0205641
Disease	Adenocarcinoma	CDKN2A VTI1A KMT2C EGFR KCNQ1	6.08e-05	116	105	5	C0001418
Disease	Neck Neoplasms	CDKN2A EGFR PRAME	9.51e-05	25	105	3	C0027533
Disease	Squamous cell carcinoma of esophagus	CDKN2A FAT3 KMT2C EGFR	3.76e-04	95	105	4	C0279626
Disease	Malignant Head and Neck Neoplasm	FANCE EGFR PRAME	5.22e-04	44	105	3	C0278996
Disease	long QT syndrome (implicated_via_orthology)	KCNQ1 KCNQ2	5.54e-04	10	105	2	DOID:2843 (implicated_via_orthology)
Disease	electrocardiography	RHBDD1 SPTBN1 VTI1A KCNA2 KCNA3 KCNA7 KCNQ1 CACNA1G	6.25e-04	530	105	8	EFO_0004327
Disease	response to ondansetron, QT interval	SLC36A2 TLR3	6.76e-04	11	105	2	EFO_0004682, EFO_0020997
Disease	lung adenocarcinoma (is_implicated_in)	KMT2C PTPN13 EGFR	7.16e-04	49	105	3	DOID:3910 (is_implicated_in)
Disease	leukemia	CDKN2A FANCE PRAME	1.00e-03	55	105	3	C0023418
Disease	head and neck squamous cell carcinoma (is_implicated_in)	CDKN2A PTPN13	1.28e-03	15	105	2	DOID:5520 (is_implicated_in)
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	SIRT6 SCD ABCG5	1.63e-03	65	105	3	DOID:0080208 (biomarker_via_orthology)
Disease	Malignant neoplasm of liver	CDKN2A WSCD1 SCD TTC39A	1.69e-03	142	105	4	C0345904
Disease	Liver neoplasms	CDKN2A WSCD1 SCD TTC39A	1.69e-03	142	105	4	C0023903
Disease	Adrenocortical carcinoma	CDKN2A EGFR	1.85e-03	18	105	2	C0206686
Disease	sucrose liking measurement	WSCD1 PCDHGB4	2.29e-03	20	105	2	EFO_0010157
Disease	Non-Small Cell Lung Carcinoma	CDKN2A GIPR EGFR PRAME	2.38e-03	156	105	4	C0007131
Disease	nose morphology measurement, mouth morphology measurement	KCNQ1 OR8D4	2.52e-03	21	105	2	EFO_0007843, EFO_0007955
Disease	total iron binding capacity	HFE DNAJC13 SLC44A4	2.74e-03	78	105	3	EFO_0006334
Disease	HbA1c measurement	CDKN2A HFE GALNS GIPR LPCAT3 KCNQ1 MACF1 ABCG5	2.87e-03	675	105	8	EFO_0004541
Disease	creatinine measurement	DNAJC13 SLC7A13 TNFRSF6B TTC27 SLC44A4 GIPR PCDHGB4 KCNQ1 ABCG5 SORL1	2.91e-03	995	105	10	EFO_0004518
Disease	Intrahepatic Cholangiocarcinoma	KMT2C EGFR	3.29e-03	24	105	2	C0345905
Disease	Extrahepatic Cholangiocarcinoma	KMT2C EGFR	3.29e-03	24	105	2	C3805278
Disease	Cancer of Head	EGFR PRAME	3.29e-03	24	105	2	C0751177
Disease	Head Neoplasms	EGFR PRAME	3.29e-03	24	105	2	C0018675
Disease	Upper Aerodigestive Tract Neoplasms	EGFR PRAME	3.29e-03	24	105	2	C0887900
Disease	thalamus volume	FAT3 EGFR MACF1	3.50e-03	85	105	3	EFO_0006935
Disease	lung adenocarcinoma (is_marker_for)	KMT2C PTPN13 PRAME	3.50e-03	85	105	3	DOID:3910 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
PLVLLRQMLLELTRR	BCL2L13	156	Q9BXK5
MDLIRGVLLRLLLLA	EGFLAM	1	Q63HQ2
INLIGRLQLTTERMR	CUL5	686	Q93034
LRELQLRNCLRILMG	BEX3	81	Q00994
RVRAMQLLLTVLIIF	GPR20	236	Q99678
MQLRLFRRLLLAALL	B3GALT4	1	O96024
AAVALVLMLLRSQRL	CDKN2A	41	Q8N726
RILGILLSKLRTRQM	GIPR	316	P48546
SFLLLPFQRITRLRM	ARHGEF15	551	O94989
MRGSLLTLQRLVQLF	ASPH	436	Q12797
MLRNLLALRQIGQRT	COX7A2	1	P14406
KGLQRLNPALRLVLM	DHX30	576	Q7L2E3
GNMLIIVVLGLSRRL	CCKBR	71	P32239
DLGTRRIQIMLLRSL	EFR3A	426	Q14156
SRLVMRTQGSLRLIL	RANBP3	441	Q9H6Z4
LLRLPALRLMNATIT	NR2C1	551	P13056
RKVGLMNRAVQLLIL	P2RX4	26	Q99571
MLLLLLRRFPETVVQ	INTS10	131	Q9NVR2
FLVAMILAIALRLRR	PCDHGB4	701	Q9UN71
MLLRGVLLALQALQL	MAMDC2	1	Q7Z304
GNLSMISIIRLNRQL	OR8D4	41	Q8NGM9
GNIMLIHLIRLNTRL	OR2AK2	56	Q8NG84
QAMSLAILRVIRLVR	KCNA2	286	P16389
AIRGIRFLQILRMLH	KCNQ1	226	P51787
ALINVELALRRGLQM	KMT2C	4446	Q8NEZ4
RLSLLLVILGVIFMN	MAGED4	501	Q96JG8
IMSVLYLLIGLRLRR	NMUR1	246	Q9HB89
GMVSQRLRLEVLNRL	ASAH2	161	Q9NR71
QTRLMKIGIVRRILL	PCNX4	436	Q63HM2
ALRSLRFLQILRMIR	KCNQ2	196	O43526
TVLEMFNTLLRQLRL	EFR3B	331	Q9Y2G0
ITLHMRRGILIRQLT	CUL7	876	Q14999
SLRNRRALILLAQMG	IFNA7	31	P01567
TLANLGRVAQVLRLM	KCNS2	286	Q9ULS6
VLLVMLRFQRTRLIF	ABCC11	151	Q96J66
QAMSLAILRVIRLVR	KCNA3	356	P22001
RSSPLQAMRILQLIL	KLK11	26	Q9UBX7
QAMRILQLILLALAT	KLK11	31	Q9UBX7
CIVLQFLILRLMGRT	LPCAT3	96	Q6P1A2
FLILRLMGRTITAVL	LPCAT3	101	Q6P1A2
MLVSGRRRLLTVLLQ	FAHD2A	1	Q96GK7
LLMLLQTAVLQGRLL	HFE	11	Q30201
AMAIIRIRSLQGRLK	OR13H1	221	Q8NG92
LIATMLVLQFIRTRL	PARP4	1626	Q9UKK3
AITLLRNLGMILLIQ	OR5J2	36	Q8NH18
SELNALMLRGLRRLR	LRIT1	96	Q9P2V4
QLRLVRILRSTVMVR	MACF1	7156	Q9UPN3
LGSVIMRRHLQRIIQ	MED14	1211	O60244
IRQVLLLFVLLGMSQ	PCDHB11	11	Q9Y5F2
ILLNILTLGMRRKNT	GPR160	36	Q9UJ42
LNLLPTLLQGRLMDR	GALNS	366	P34059
LLLVVALGIGLFMRR	EGFR	656	P00533
MRLVDLLLVLLFEGR	HECTD1	321	Q9ULT8
MSRLPVLLLLQLLVR	IL3	1	P08700
QLRLSGLEMLLVVIR	HEATR5A	1281	Q86XA9
MRALRRLIQGRILLL	SLC2A11	1	Q9BYW1
MSLAILRVIRLVRVF	KCNA6	336	P17658
AMSLAILRVIRLVRV	KCNA7	271	Q96RP8
INRVPSMRILVTLLL	CACNA1G	191	O43497
TKILGMLRVLRLLRT	CACNA1G	1371	O43497
MLVSGRRRLLTALLQ	FAHD2B	1	Q6P2I3
LALRLRTLQSNGIIM	FAT3	3861	Q8TDW7
VITRLLQNLIMGLFL	ABCG5	386	Q9H222
LMGLIRQQRLLRLCE	ELMO3	531	Q96BJ8
RMLTNRQLSRHLVGL	DNAJC13	626	O75165
MLIFLRQRIRIAIAL	SLC44A4	326	Q53GD3
SLGNRRALILLAQMR	IFNA8	31	P32881
LLLRLPRICQRNLMS	FANCE	86	Q9HB96
REMQLLKGLLSRVVL	FCRLB	376	Q6BAA4
MRAARAAPLLQLLLL	CERCAM	1	Q5T4B2
MGLLQGLLRVRKLLL	SLC13A4	1	Q9UKG4
RLRLALVRMQQLKGF	PTPN13	2336	Q12923
MVARVGLLLRALQLL	MMP28	1	Q9H239
FRRLLKIMNLQQIGR	PIWIL1	216	Q96J94
LSQLLNLQLRRMPIL	SORL1	481	Q92673
MQRRSRGINTGLILL	RHBDD1	1	Q8TEB9
RRRMALGIVILLLVD	SLC35F5	66	Q8WV83
LGQMINLRRLLLSHI	PRAME	256	P78395
RLRRQGKNLMFLVLR	NARS1	136	O43776
VLRKAMARGQLLLQR	TAF1C	681	Q15572
MSLRQRLAQLVGRLQ	SGPP1	1	Q9BX95
ILRILIGMVFVLIIR	SGPP1	366	Q9BX95
VLIRNLRILTIFSML	SLC36A2	216	Q495M3
ALLRLNAEKLQRMGL	SAMD10	151	Q9BYL1
MALVQLERVGLLRFL	SIRT6	96	Q8N6T7
LLRARRQRLEMNLGL	SPTBN1	516	Q01082
GFGVLLSRMLLQQLR	CHPF	246	Q8IZ52
MAQRLLLRRFLASVI	TXN2	1	Q99757
RNMRRVVLLLGLLNE	RNF213	3556	Q63HN8
LNTVLRRLPMLSLFR	MRPS18B	6	Q9Y676
QETMKRQLGRLLLLL	TBC1D17	456	Q9HA65
FALVPSLQRLMLRRV	TLR3	476	O15455
VRTPTLQRALLNLML	TMEM143	271	Q96AN5
HLRPSMLQQLLRRLV	RYR3	2476	Q15413
RSLALGIQFMVLRLL	SLCO4C1	611	Q6ZQN7
LIMRNQGSLRLILNS	RANBP3L	341	Q86VV4
LTGMLRRIIQNRILL	VTI1A	181	Q96AJ9
MILGLIIVRRLLDFI	SLC4A5	1046	Q9BY07
SILALLPRVLRLMLQ	TEX10	831	Q9NXF1
LPRVLRLMLQSLRVN	TEX10	836	Q9NXF1
RLPLRLFLIIANTMA	SCD	131	O00767
SILLMIGILRRRYQE	SLC7A13	371	Q8TCU3
QSLLMRLGLIRQKVL	UBE2Z	311	Q9H832
LQLLVSRLMGRLASQ	ZZEF1	1206	O43149
MARGSLRRLLRLLVL	TNFRSF12A	1	Q9NP84
QLILLSRIIHMLRLG	SCN7A	1346	Q01118
LIQLTVIMGYLRIIR	SLC9C2	701	Q5TAH2
GRLARLLSITLIIMG	TRARG1	146	Q8IXB3
MLLLHRAVVLRLQQA	SUOX	1	P51687
YLMTGSLLLLQRVRV	WSCD1	26	Q658N2
IRMLVLLLDLLGLVQ	ZDHHC11B	236	P0C7U3
QMLSSVRLNLRGLLS	TTC27	786	Q6P3X3
AQMRFVPLILARLLL	UBR4	846	Q5T4S7
QKMLPLLSQRRFVLL	TTLL10	551	Q6ZVT0
NLTLSMLPTRILRLL	TTC39A	231	Q5SRH9
ALLVRLLQALRVARM	TNFRSF6B	271	O95407
LAMLLRGLTQIQSRI	GEMIN4	216	P57678
KSLLIRRGLQVMNLE	LDAH	206	Q9H6V9
EELRAQMLIRIVLFL	MYO1D	691	O94832