Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC25A18 CEACAM6 GRIA1 GRIA2 GRIK1 SLC7A1 SLC16A11 SERINC5	2.20e-05	207	112	8	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC25A18 CEACAM6 GRIA1 GRIA2 GRIK1 SLC7A1 SLC16A11 SERINC5	2.28e-05	208	112	8	GO:0005342
GeneOntologyMolecularFunction	phosphatidyl phospholipase B activity	PNPLA6 PNPLA8 PNPLA7	2.74e-05	11	112	3	GO:0102545
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	SLC25A18 GRIA1 GRIA2 GRIK1 SLC7A1 SERINC5	2.79e-05	105	112	6	GO:0015171
GeneOntologyMolecularFunction	transmembrane transporter activity	ANO4 ATP5MC3 SLC25A18 ABCA3 ABCB5 CEACAM6 GRIA1 GRIA2 GRIK1 ITPR3 SLC7A1 SLC9A1 SLC9A2 KCNF1 ATP2C2 PKD1 SLC16A11 SERINC5 ABCC10	2.91e-05	1180	112	19	GO:0022857
GeneOntologyMolecularFunction	cyclin binding	CDK12 HDAC3 CDK13 FBXO31	4.29e-05	35	112	4	GO:0030332
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCA3 ABCB5 ABCC10	7.44e-05	15	112	3	GO:0008559
GeneOntologyMolecularFunction	6-phosphofructokinase activity	PFKL PFKM	9.32e-05	3	112	2	GO:0003872
GeneOntologyMolecularFunction	transporter activity	ANO4 ATP5MC3 SLC25A18 ABCA3 ABCB5 CEACAM6 GRIA1 GRIA2 GRIK1 ITPR3 SLC7A1 SLC9A1 SLC9A2 KCNF1 ATP2C2 PKD1 SLC16A11 SERINC5 ABCC10	9.54e-05	1289	112	19	GO:0005215
GeneOntologyMolecularFunction	glutamate-gated receptor activity	GRIA1 GRIA2 GRIK1	1.10e-04	17	112	3	GO:0004970
GeneOntologyMolecularFunction	AMPA glutamate receptor activity	GRIA1 GRIA2	1.86e-04	4	112	2	GO:0004971
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC25A18 CEACAM6 GRIA1 GRIA2 GRIK1 SLC7A1 SLC16A11 SERINC5	2.48e-04	293	112	8	GO:0008514
GeneOntologyMolecularFunction	fructose-6-phosphate binding	PFKL PFKM	3.08e-04	5	112	2	GO:0070095
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIA1 GRIA2 GRIK1	3.19e-04	24	112	3	GO:0099507
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	ANO4 ATP5MC3 SLC25A18 GRIA1 GRIA2 GRIK1 ITPR3 SLC9A1 SLC9A2 KCNF1 ATP2C2 PKD1 ABCC10	3.27e-04	758	112	13	GO:0015318
GeneOntologyMolecularFunction	kinase binding	CDK12 CEACAM3 DVL1 CEACAM6 GRIA1 GRIA2 PFKL PFKM ITGAX AP2A2 CDK13 PKD1 TJP2 ELP2 LRBA	3.35e-04	969	112	15	GO:0019900
GeneOntologyMolecularFunction	MAP kinase kinase kinase activity	MAP3K9 MAP3K10 MAP3K15	4.55e-04	27	112	3	GO:0004709
GeneOntologyMolecularFunction	glutamate receptor activity	GRIA1 GRIA2 GRIK1	4.55e-04	27	112	3	GO:0008066
GeneOntologyMolecularFunction	fructose binding	PFKL PFKM	4.61e-04	6	112	2	GO:0070061
GeneOntologyMolecularFunction	kainate selective glutamate receptor activity	GRIA2 GRIK1	4.61e-04	6	112	2	GO:0015277
GeneOntologyMolecularFunction	lysophospholipase activity	PNPLA6 PNPLA8 PNPLA7	5.64e-04	29	112	3	GO:0004622
GeneOntologyMolecularFunction	extracellularly glutamate-gated ion channel activity	GRIA2 GRIK1	6.43e-04	7	112	2	GO:0005234
GeneOntologyMolecularFunction	phosphofructokinase activity	PFKL PFKM	6.43e-04	7	112	2	GO:0008443
GeneOntologyMolecularFunction	L-amino acid transmembrane transporter activity	SLC25A18 GRIK1 SLC7A1 SERINC5	6.82e-04	71	112	4	GO:0015179
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	GRIA1 GRIK1 ITPR3	6.89e-04	31	112	3	GO:0099604
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	ATP5MC3 SLC25A18 GRIA1 GRIA2 GRIK1 ITPR3 SLC9A1 SLC9A2 KCNF1 ATP2C2 PKD1	7.98e-04	627	112	11	GO:0022890
GeneOntologyMolecularFunction	glutamate-gated calcium ion channel activity	GRIA1 GRIK1	8.54e-04	8	112	2	GO:0022849
GeneOntologyMolecularFunction	ligand-gated channel activity	ANO4 ATP5MC3 GRIA1 GRIA2 GRIK1 ITPR3	8.60e-04	197	112	6	GO:0022834
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	ABCA3 ABCB5 ABCC10	9.06e-04	34	112	3	GO:0042910
GeneOntologyMolecularFunction	protein kinase binding	CDK12 CEACAM3 DVL1 CEACAM6 GRIA1 GRIA2 ITGAX AP2A2 CDK13 PKD1 TJP2 ELP2 LRBA	1.22e-03	873	112	13	GO:0019901
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	GRIA1 GRIA2 GRIK1 ITPR3 SLC9A1 SLC9A2 KCNF1 ATP2C2 PKD1	1.23e-03	465	112	9	GO:0046873
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	ATP5MC3 SLC25A18 GRIA1 GRIA2 GRIK1 ITPR3 SLC9A1 SLC9A2 KCNF1 ATP2C2 PKD1	1.27e-03	664	112	11	GO:0008324
GeneOntologyMolecularFunction	RNA polymerase II CTD heptapeptide repeat kinase activity	CDK12 CDK13	1.36e-03	10	112	2	GO:0008353
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	GRIA1 GRIK1 ITPR3 ATP2C2 PKD1	1.62e-03	151	112	5	GO:0015085
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	ANO4 ATP5MC3 SLC25A18 GRIA1 GRIA2 GRIK1 ITPR3 SLC9A1 SLC9A2 KCNF1 ATP2C2 PKD1	1.65e-03	793	112	12	GO:0015075
GeneOntologyMolecularFunction	JUN kinase kinase kinase activity	MAP3K9 MAP3K10	1.98e-03	12	112	2	GO:0004706
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	GRIA2 GRIK1 SLC9A1 SLC9A2 KCNF1	2.52e-03	167	112	5	GO:0015079
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA3 ABCB5 ABCC10	2.62e-03	49	112	3	GO:0140359
GeneOntologyMolecularFunction	potassium:proton antiporter activity	SLC9A1 SLC9A2	2.72e-03	14	112	2	GO:0015386
GeneOntologyMolecularFunction	gated channel activity	ANO4 ATP5MC3 GRIA1 GRIA2 GRIK1 ITPR3 KCNF1	2.78e-03	334	112	7	GO:0022836
GeneOntologyMolecularFunction	L-glutamate transmembrane transporter activity	SLC25A18 GRIK1	3.12e-03	15	112	2	GO:0005313
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA3 ABCB5 ATP2C2 ABCC10	3.32e-03	109	112	4	GO:0042626
GeneOntologyMolecularFunction	exopeptidase activity	CPXM2 PRSS16 DPEP3 DNPEP	3.43e-03	110	112	4	GO:0008238
GeneOntologyMolecularFunction	sodium:proton antiporter activity	SLC9A1 SLC9A2	3.55e-03	16	112	2	GO:0015385
GeneOntologyMolecularFunction	kinase activity	CDK12 CHEK1 PFKL PFKM CDC42BPB CDK13 MAP3K9 MAP3K10 TJP2 MAP3K15 LTK	3.77e-03	764	112	11	GO:0016301
GeneOntologyMolecularFunction	phospholipase activity	GPLD1 PNPLA6 PNPLA8 PNPLA7	3.90e-03	114	112	4	GO:0004620
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GRIA1 GRIA2 GRIK1	4.03e-03	57	112	3	GO:1904315
GeneOntologyMolecularFunction	protein serine kinase activity	CDK12 CHEK1 CDC42BPB CDK13 MAP3K9 MAP3K10 MAP3K15	4.39e-03	363	112	7	GO:0106310
GeneOntologyMolecularFunction	ligand-gated sodium channel activity	GRIA2 GRIK1	4.50e-03	18	112	2	GO:0015280
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	GRIA1 GRIA2 GRIK1	4.66e-03	60	112	3	GO:0099529
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	ANO4 GRIA1 GRIA2 GRIK1 ITPR3	4.67e-03	193	112	5	GO:0015276
GeneOntologyMolecularFunction	solute:potassium antiporter activity	SLC9A1 SLC9A2	5.01e-03	19	112	2	GO:0022821
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC25A18 ABCA3 ABCB5 SLC9A1 SLC9A2 ATP2C2 SLC16A11 ABCC10	5.46e-03	477	112	8	GO:0022804
GeneOntologyMolecularFunction	acidic amino acid transmembrane transporter activity	SLC25A18 GRIK1	5.55e-03	20	112	2	GO:0015172
GeneOntologyMolecularFunction	transmitter-gated channel activity	GRIA1 GRIA2 GRIK1	5.83e-03	65	112	3	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	GRIA1 GRIA2 GRIK1	5.83e-03	65	112	3	GO:0022824
GeneOntologyMolecularFunction	calcium channel activity	GRIA1 GRIK1 ITPR3 PKD1	6.03e-03	129	112	4	GO:0005262
GeneOntologyMolecularFunction	AMP binding	PFKL PFKM	6.11e-03	21	112	2	GO:0016208
GeneOntologyMolecularFunction	carbohydrate kinase activity	PFKL PFKM	6.11e-03	21	112	2	GO:0019200
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	CDK12 CHEK1 PFKL PFKM CDC42BPB PNPT1 CDK13 MAP3K9 MAP3K10 TJP2 MAP3K15 LTK	6.37e-03	938	112	12	GO:0016772
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CDK12 CHEK1 PFKL PFKM CDC42BPB CDK13 MAP3K9 MAP3K10 MAP3K15 LTK	6.55e-03	709	112	10	GO:0016773
GeneOntologyMolecularFunction	semaphorin receptor binding	SEMA4G SEMA4A	7.30e-03	23	112	2	GO:0030215
GeneOntologyMolecularFunction	RNA polymerase II CTD heptapeptide repeat modifying activity	CDK12 CDK13	7.30e-03	23	112	2	GO:0140994
GeneOntologyMolecularFunction	lipase activity	GPLD1 PNPLA6 PNPLA8 PNPLA7	7.63e-03	138	112	4	GO:0016298
GeneOntologyCellularComponent	6-phosphofructokinase complex	PFKL PFKM	8.20e-05	3	110	2	GO:0005945
GeneOntologyCellularComponent	secretory vesicle	ABCA3 ACLY CEACAM3 DVL1 PSMB7 CEACAM6 GRIA1 GRIA2 SYNDIG1 PFKL ITGAL ITGAX ITPR3 GTPBP2 AP2A2 CDK13 DPEP3 ADGRE5	8.53e-05	1246	110	18	GO:0099503
GeneOntologyCellularComponent	perisynaptic space	GRIA1 GRIA2	1.64e-04	4	110	2	GO:0099544
GeneOntologyCellularComponent	secretory granule	ABCA3 ACLY CEACAM3 DVL1 PSMB7 CEACAM6 PFKL ITGAL ITGAX ITPR3 GTPBP2 AP2A2 CDK13 DPEP3 ADGRE5	2.74e-04	1014	110	15	GO:0030141
GeneOntologyCellularComponent	secretory granule membrane	ABCA3 CEACAM3 CEACAM6 ITGAL ITGAX ITPR3 AP2A2 ADGRE5	3.52e-04	329	110	8	GO:0030667
GeneOntologyCellularComponent	stereocilia ankle link	ADGRV1 USH1C	4.06e-04	6	110	2	GO:0002141
GeneOntologyCellularComponent	stereocilia ankle link complex	ADGRV1 USH1C	4.06e-04	6	110	2	GO:0002142
GeneOntologyCellularComponent	ficolin-1-rich granule	ACLY PSMB7 PFKL ITGAX AP2A2 CDK13	4.43e-04	185	110	6	GO:0101002
GeneOntologyCellularComponent	stereocilia coupling link	ADGRV1 USH1C	7.53e-04	8	110	2	GO:0002139
GeneOntologyCellularComponent	cyclin/CDK positive transcription elongation factor complex	CDK12 CDK13	9.64e-04	9	110	2	GO:0008024
GeneOntologyCellularComponent	Cul3-RING ubiquitin ligase complex	KLHL40 KLHL9 KLHL7	1.13e-03	39	110	3	GO:0031463
Domain	Kelch_1	KLHL6 KLHL40 IPP KLHL9 KLHL7 KLHL36 HCFC1	1.91e-07	70	111	7	PF01344
Domain	Kelch_1	KLHL6 KLHL40 IPP KLHL9 KLHL7 KLHL36 HCFC1	1.91e-07	70	111	7	IPR006652
Domain	BTB-kelch_protein	KLHL6 KLHL40 IPP KLHL9 KLHL7 KLHL36	1.96e-07	43	111	6	IPR017096
Domain	Kelch-typ_b-propeller	KLHL6 KLHL40 IPP KLHL7 KLHL36 HCFC1	8.80e-07	55	111	6	IPR015915
Domain	Kelch	KLHL6 KLHL40 IPP KLHL9 KLHL7 KLHL36	1.21e-06	58	111	6	SM00612
Domain	Gal_Oxase/kelch_b-propeller	KLHL6 KLHL40 IPP KLHL9 KLHL36 HCFC1	1.34e-06	59	111	6	IPR011043
Domain	BACK	KLHL6 KLHL40 IPP KLHL9 KLHL7 KLHL36	1.48e-06	60	111	6	SM00875
Domain	BACK	KLHL6 KLHL40 IPP KLHL9 KLHL7 KLHL36	1.64e-06	61	111	6	IPR011705
Domain	BACK	KLHL6 KLHL40 IPP KLHL9 KLHL7 KLHL36	1.64e-06	61	111	6	PF07707
Domain	-	KLHL6 KLHL40 IPP KLHL7 HCFC1	9.46e-06	48	111	5	2.120.10.80
Domain	Patatin	PNPLA6 PNPLA8 PNPLA7	1.67e-05	9	111	3	PF01734
Domain	PNPLA	PNPLA6 PNPLA8 PNPLA7	1.67e-05	9	111	3	PS51635
Domain	Patatin/PLipase_A2-rel	PNPLA6 PNPLA8 PNPLA7	1.67e-05	9	111	3	IPR002641
Domain	DVL-1	DVL1P1 DVL1	3.50e-05	2	111	2	IPR008340
Domain	UPF0028	PNPLA6 PNPLA7	3.50e-05	2	111	2	PS01237
Domain	Gal_Oxidase_b-propeller	IPP KLHL9 KLHL36 HCFC1	4.78e-05	34	111	4	IPR015916
Domain	BTB	KLHL6 KLHL40 IPP KLHL9 KLHL7 KCNF1 KLHL36	1.00e-04	180	111	7	SM00225
Domain	6-Pfructokinase_euk	PFKL PFKM	1.05e-04	3	111	2	IPR009161
Domain	NHE_CaM-bd	SLC9A1 SLC9A2	1.05e-04	3	111	2	IPR032103
Domain	PHOSPHOFRUCTOKINASE	PFKL PFKM	1.05e-04	3	111	2	PS00433
Domain	Phosphofructokinase_CS	PFKL PFKM	1.05e-04	3	111	2	IPR015912
Domain	PFK	PFKL PFKM	1.05e-04	3	111	2	PF00365
Domain	ATP_PFK	PFKL PFKM	1.05e-04	3	111	2	IPR022953
Domain	NEXCaM_BD	SLC9A1 SLC9A2	1.05e-04	3	111	2	PF16644
Domain	Phosphofructokinase_dom	PFKL PFKM	1.05e-04	3	111	2	IPR000023
Domain	BTB/POZ_dom	KLHL6 KLHL40 IPP KLHL9 KLHL7 KCNF1 KLHL36	1.19e-04	185	111	7	IPR000210
Domain	Acyl_Trfase/lysoPLipase	PNPLA6 PNPLA8 PNPLA7	1.31e-04	17	111	3	IPR016035
Domain	BTB	KLHL6 KLHL40 IPP KLHL9 KLHL7 KLHL36	1.32e-04	131	111	6	PF00651
Domain	SKP1/BTB/POZ	KLHL6 KLHL40 IPP KLHL9 KLHL7 KCNF1 KLHL36	1.36e-04	189	111	7	IPR011333
Domain	Lig_chan-Glu_bd	GRIA1 GRIA2 GRIK1	1.56e-04	18	111	3	PF10613
Domain	Glu/Gly-bd	GRIA1 GRIA2 GRIK1	1.56e-04	18	111	3	IPR019594
Domain	Lig_chan-Glu_bd	GRIA1 GRIA2 GRIK1	1.56e-04	18	111	3	SM00918
Domain	Iontro_rcpt	GRIA1 GRIA2 GRIK1	1.56e-04	18	111	3	IPR001320
Domain	Iono_rcpt_met	GRIA1 GRIA2 GRIK1	1.56e-04	18	111	3	IPR001508
Domain	Lig_chan	GRIA1 GRIA2 GRIK1	1.56e-04	18	111	3	PF00060
Domain	PBPe	GRIA1 GRIA2 GRIK1	1.56e-04	18	111	3	SM00079
Domain	SH3_2	DOCK3 SH3TC2 MAP3K9 MAP3K10 TJP2	1.61e-04	86	111	5	PF07653
Domain	SH3_2	DOCK3 SH3TC2 MAP3K9 MAP3K10 TJP2	1.61e-04	86	111	5	IPR011511
Domain	Int_alpha	GPLD1 ITGAL ITGAX	1.85e-04	19	111	3	SM00191
Domain	Int_alpha_beta-p	GPLD1 ITGAL ITGAX	1.85e-04	19	111	3	IPR013519
Domain	PDZ	DVL1P1 MAGIX DVL1 USH1C TJP2 PATJ	1.97e-04	141	111	6	PF00595
Domain	Dishevelled	DVL1P1 DVL1	2.08e-04	4	111	2	PF02377
Domain	Dishevelled_fam	DVL1P1 DVL1	2.08e-04	4	111	2	IPR008339
Domain	MLK1/MLK2/MLK4	MAP3K9 MAP3K10	2.08e-04	4	111	2	IPR016231
Domain	Dishevelled_protein_dom	DVL1P1 DVL1	2.08e-04	4	111	2	IPR003351
Domain	MAP3K10	MAP3K9 MAP3K10	2.08e-04	4	111	2	IPR015785
Domain	PDZ	DVL1P1 MAGIX DVL1 USH1C TJP2 PATJ	2.56e-04	148	111	6	SM00228
Domain	PDZ	DVL1P1 MAGIX DVL1 USH1C TJP2 PATJ	2.85e-04	151	111	6	PS50106
Domain	DEP	GPR155 DVL1P1 DVL1	2.90e-04	22	111	3	PF00610
Domain	DEP	GPR155 DVL1P1 DVL1	2.90e-04	22	111	3	PS50186
Domain	FG_GAP	GPLD1 ITGAL ITGAX	2.90e-04	22	111	3	PS51470
Domain	DEP	GPR155 DVL1P1 DVL1	2.90e-04	22	111	3	SM00049
Domain	PDZ	DVL1P1 MAGIX DVL1 USH1C TJP2 PATJ	2.95e-04	152	111	6	IPR001478
Domain	DEP_dom	GPR155 DVL1P1 DVL1	3.32e-04	23	111	3	IPR000591
Domain	FG-GAP	GPLD1 ITGAL ITGAX	3.78e-04	24	111	3	PF01839
Domain	FG-GAP	GPLD1 ITGAL ITGAX	3.78e-04	24	111	3	IPR013517
Domain	BTB	KLHL6 KLHL40 IPP KLHL9 KLHL7 KLHL36	3.88e-04	160	111	6	PS50097
Domain	-	KLHL9 KLHL36 HCFC1	5.39e-04	27	111	3	2.130.10.80
Domain	DIX	DVL1P1 DVL1	7.21e-04	7	111	2	PF00778
Domain	DIX	DVL1P1 DVL1	7.21e-04	7	111	2	IPR001158
Domain	DIX	DVL1P1 DVL1	7.21e-04	7	111	2	PS50841
Domain	DAX	DVL1P1 DVL1	7.21e-04	7	111	2	SM00021
Domain	GPS	ADGRV1 PKD1 ADGRE5	1.07e-03	34	111	3	SM00303
Domain	GPS	ADGRV1 PKD1 ADGRE5	1.16e-03	35	111	3	PF01825
Domain	NaH_exchanger	SLC9A1 SLC9A2	1.23e-03	9	111	2	IPR004709
Domain	GPS	ADGRV1 PKD1 ADGRE5	1.26e-03	36	111	3	PS50221
Domain	ANF_lig-bd_rcpt	GRIA1 GRIA2 GRIK1	1.37e-03	37	111	3	IPR001828
Domain	ANF_receptor	GRIA1 GRIA2 GRIK1	1.37e-03	37	111	3	PF01094
Domain	GPS	ADGRV1 PKD1 ADGRE5	1.37e-03	37	111	3	IPR000203
Domain	Peripla_BP_I	GRIA1 GRIA2 GRIK1	1.60e-03	39	111	3	IPR028082
Domain	Integrin_alpha	ITGAL ITGAX	1.86e-03	11	111	2	PF00357
Domain	Cation/H_exchanger_CPA1	SLC9A1 SLC9A2	1.86e-03	11	111	2	IPR018422
Domain	Protein_kinase_ATP_BS	CDK12 CHEK1 CDC42BPB CDK13 MAP3K9 MAP3K10 MAP3K15 LTK	1.92e-03	379	111	8	IPR017441
Domain	ABC_transporter_CS	ABCA3 ABCB5 ABCC10	1.98e-03	42	111	3	IPR017871
Domain	-	MAGIX DVL1 USH1C TJP2 PATJ	2.02e-03	150	111	5	2.30.42.10
Domain	FAD-dep_OxRdtase	FOXRED1 PIPOX	2.22e-03	12	111	2	IPR006076
Domain	DAO	FOXRED1 PIPOX	2.22e-03	12	111	2	PF01266
Domain	Kelch_2	KLHL36 HCFC1	2.62e-03	13	111	2	IPR011498
Domain	Kelch_2	KLHL36 HCFC1	2.62e-03	13	111	2	PF07646
Domain	ABC_tran	ABCA3 ABCB5 ABCC10	2.91e-03	48	111	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCA3 ABCB5 ABCC10	2.91e-03	48	111	3	PS50893
Domain	Na_H_Exchanger	SLC9A1 SLC9A2	3.04e-03	14	111	2	PF00999
Domain	Cation/H_exchanger	SLC9A1 SLC9A2	3.04e-03	14	111	2	IPR006153
Domain	ABC_TRANSPORTER_1	ABCA3 ABCB5 ABCC10	3.09e-03	49	111	3	PS00211
Domain	ABC_transporter-like	ABCA3 ABCB5 ABCC10	3.27e-03	50	111	3	IPR003439
Domain	Integrin_alpha_C_CS	ITGAL ITGAX	3.98e-03	16	111	2	IPR018184
Domain	Integrin_alpha-2	ITGAL ITGAX	5.03e-03	18	111	2	IPR013649
Domain	INTEGRIN_ALPHA	ITGAL ITGAX	5.03e-03	18	111	2	PS00242
Domain	ALDEHYDE_DEHYDR_CYS	ALDH1L2 ALDH16A1	5.03e-03	18	111	2	PS00070
Domain	Integrin_alpha2	ITGAL ITGAX	5.03e-03	18	111	2	PF08441
Domain	ALDEHYDE_DEHYDR_GLU	ALDH1L2 ALDH16A1	5.03e-03	18	111	2	PS00687
Domain	Integrin_alpha	ITGAL ITGAX	5.03e-03	18	111	2	IPR000413
Domain	Ser/Thr_kinase_AS	CDK12 CHEK1 CDC42BPB CDK13 MAP3K9 MAP3K10 MAP3K15	5.47e-03	357	111	7	IPR008271
Domain	-	PRSS16 ACOT4 NDRG3 PREP	5.56e-03	119	111	4	3.40.50.1820
Domain	AB_hydrolase	PRSS16 ACOT4 NDRG3 PREP	5.56e-03	119	111	4	IPR029058
Domain	-	ALDH1L2 ALDH16A1	5.60e-03	19	111	2	3.40.605.10
Domain	Aldedh	ALDH1L2 ALDH16A1	5.60e-03	19	111	2	PF00171
Domain	Ald_DH_C	ALDH1L2 ALDH16A1	5.60e-03	19	111	2	IPR016163
Domain	Ald_DH_N	ALDH1L2 ALDH16A1	5.60e-03	19	111	2	IPR016162
Domain	Ald_DH/histidinol_DH	ALDH1L2 ALDH16A1	5.60e-03	19	111	2	IPR016161
Pubmed	Update on the Kelch-like (KLHL) gene family.	KLHL6 KLHL40 IPP KLHL9 KLHL7 KLHL36	4.22e-09	41	113	6	23676014
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TANC2 DOCK3 ENGASE CDK12 DVL1 IPP CUL9 CDC42BPB ITPR3 SLC7A1 PNPLA6 KLHL36 CDK13 PKD1 LTK LRBA HCFC1 ABCC10	1.86e-08	1105	113	18	35748872
Pubmed	Changes in subcellular localization of metabotropic glutamate receptor subtypes during postnatal development of mouse thalamus.	GRIA1 GRIA2 GRIK1	1.33e-07	4	113	3	9619499
Pubmed	SynDIG1: an activity-regulated, AMPA- receptor-interacting transmembrane protein that regulates excitatory synapse development.	GRIA1 GRIA2 SYNDIG1	6.63e-07	6	113	3	20152115
Pubmed	The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1.	ITGAL ITGAX JAM3	6.63e-07	6	113	3	12208882
Pubmed	Glutamate receptors in cortical plasticity: molecular and cellular biology.	GRIA1 GRIA2 GRIK1	1.16e-06	7	113	3	9016303
Pubmed	Glutamate receptors: brain function and signal transduction.	GRIA1 GRIA2 GRIK1	1.16e-06	7	113	3	9651535
Pubmed	Primary structure and expression of the gamma 2 subunit of the glutamate receptor channel selective for kainate.	GRIA1 GRIA2 GRIK1	1.16e-06	7	113	3	1310861
Pubmed	Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions.	PNPLA6 PNPLA8 PNPLA7	2.77e-06	9	113	3	19029121
Pubmed	Expression of glutamate receptor subunit genes during development of the mouse retina.	GRIA1 GRIA2 GRIK1	2.77e-06	9	113	3	9051806
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	TANC2 CUL9 PFKL USH1C ITPR3 PREP SVIL TJP2 ABCC10	3.66e-06	371	113	9	15747579
Pubmed	Characterization of the human patatin-like phospholipase family.	PNPLA6 PNPLA8 PNPLA7	3.94e-06	10	113	3	16799181
Pubmed	Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo.	GRIA1 GRIA2 SYNDIG1	3.94e-06	10	113	3	27800545
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	TANC2 DOCK3 DNAJC16 DVL1 GRIA1 GRIA2 MCCC2 PFKL NDRG3 CDC42BPB ARCN1 AP2A2 KCNF1 MAP3K10 TJP2	4.41e-06	1139	113	15	36417873
Pubmed	SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and Plasticity Underlying Cognitive Function.	GRIA1 GRIA2 SYNDIG1	5.41e-06	11	113	3	29490264
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	CDK12 ACLY DVL1 PSMB7 CDC42BPB AP2A2 CDK13 SVIL PNPLA8 HCFC1	5.51e-06	498	113	10	36634849
Pubmed	The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs.	GRIA1 GRIA2 GRIK1	7.19e-06	12	113	3	11891216
Pubmed	Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity.	PNPLA6 PNPLA7	1.05e-05	2	113	2	12640454
Pubmed	Insulin specifically regulates expression of liver and muscle phosphofructokinase isoforms.	PFKL PFKM	1.05e-05	2	113	2	29655163
Pubmed	Possible acceleration of regression by antibiotic treatment in benign cephalic histiocytosis with infiltration of CD11a/CD11c+ macrophages.	ITGAL ITGAX	1.05e-05	2	113	2	20574620
Pubmed	Reactive oxygen species (ROS) modulate AMPA receptor phosphorylation and cell-surface localization in concert with pain-related behavior.	GRIA1 GRIA2	1.05e-05	2	113	2	22770842
Pubmed	Human Autoantibodies against the AMPA Receptor Subunit GluA2 Induce Receptor Reorganization and Memory Dysfunction.	GRIA1 GRIA2	1.05e-05	2	113	2	30146304
Pubmed	Peripheral calcium-permeable AMPA receptors regulate chronic inflammatory pain in mice.	GRIA1 GRIA2	1.05e-05	2	113	2	21383497
Pubmed	Altered AMPA receptor expression with treadmill exercise in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury.	GRIA1 GRIA2	1.05e-05	2	113	2	19746427
Pubmed	Simultaneous disturbance of NHE1 and LOXL2 decreases tumorigenicity of head and neck squamous cell carcinoma.	SLC9A1 LOXL2	1.05e-05	2	113	2	38520980
Pubmed	Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase.	PNPLA6 PNPLA7	1.05e-05	2	113	2	18086666
Pubmed	The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis.	MAP3K9 MAP3K10	1.05e-05	2	113	2	11416147
Pubmed	Human CDK12 and CDK13, multi-tasking CTD kinases for the new millenium.	CDK12 CDK13	1.05e-05	2	113	2	30319007
Pubmed	Involvement of AMPA receptor GluR2 subunits in stimulus-reward learning: evidence from glutamate receptor gria2 knock-out mice.	GRIA1 GRIA2	1.05e-05	2	113	2	14573529
Pubmed	A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-A.	GRIA1 GRIA2	1.05e-05	2	113	2	14555717
Pubmed	AMPA receptor regulation during synaptic plasticity in hippocampus and neocortex.	GRIA1 GRIA2	1.05e-05	2	113	2	21856433
Pubmed	Characterization of human cyclin-dependent kinase 12 (CDK12) and CDK13 complexes in C-terminal domain phosphorylation, gene transcription, and RNA processing.	CDK12 CDK13	1.05e-05	2	113	2	25561469
Pubmed	Molecular cloning, chromosomal mapping, and functional expression of human brain glutamate receptors.	GRIA1 GRIA2	1.05e-05	2	113	2	1311100
Pubmed	Isozyme analysis of human polymorphonuclear leukocyte phosphofructokinase from insulin resistant individuals.	PFKL PFKM	1.05e-05	2	113	2	8780720
Pubmed	Functional expression from cloned cDNAs of glutamate receptor species responsive to kainate and quisqualate.	GRIA1 GRIA2	1.05e-05	2	113	2	1699805
Pubmed	The dorsal hippocampal protein targeting to glycogen maintains ionotropic glutamate receptor subunits expression and contributes to working and short-term memories in mice.	GRIA1 GRIA2	1.05e-05	2	113	2	34924114
Pubmed	Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains.	MAP3K9 MAP3K10	1.05e-05	2	113	2	8477742
Pubmed	Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2.	MAP3K9 MAP3K10	1.05e-05	2	113	2	8536694
Pubmed	The AMPA receptor subunits GluR-A and GluR-B reciprocally modulate spinal synaptic plasticity and inflammatory pain.	GRIA1 GRIA2	1.05e-05	2	113	2	15541312
Pubmed	Hierarchical fine mapping of the cystic fibrosis modifier locus on 19q13 identifies an association with two elements near the genes CEACAM3 and CEACAM6.	CEACAM3 CEACAM6	1.05e-05	2	113	2	20047061
Pubmed	The molecular mechanism of the inherited phosphofructokinase deficiency associated with hemolysis and myopathy.	PFKL PFKM	1.05e-05	2	113	2	6444532
Pubmed	Dendritic cells as host cells for the promastigote and amastigote stages of Leishmania amazonensis: the role of opsonins in parasite uptake and dendritic cell maturation.	ITGAL ITGAX	1.05e-05	2	113	2	14657281
Pubmed	Expression, Localization and Functional Activity of the Major Na⁺/H⁺ Exchange Isoforms Expressed in the Intestinal Cell Line Caco-2BBe.	SLC9A1 SLC9A2	1.05e-05	2	113	2	30977986
Pubmed	Synaptic AMPA receptor exchange maintains bidirectional plasticity.	GRIA1 GRIA2	1.05e-05	2	113	2	16600857
Pubmed	Activation of leukocyte beta2 integrins by conversion from bent to extended conformations.	ITGAL ITGAX	1.05e-05	2	113	2	17045822
Pubmed	CD11c participates in triggering acute graft-versus-host disease during bone marrow transplantation.	ITGAL ITGAX	1.05e-05	2	113	2	33934334
Pubmed	Different Forms of AMPA Receptor Mediated LTP and Their Correlation to the Spatial Working Memory Formation.	GRIA1 GRIA2	1.05e-05	2	113	2	28725178
Pubmed	Differential distribution of ionotropic glutamate receptor subunits in the rat olfactory bulb.	GRIA1 GRIK1	1.05e-05	2	113	2	10023812
Pubmed	Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression.	CDK12 CDK13	1.05e-05	2	113	2	24999027
Pubmed	Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice.	GRIA1 GRIA2	1.05e-05	2	113	2	7502080
Pubmed	New insights in endosomal dynamics and AMPA receptor trafficking.	GRIA1 GRIA2	1.05e-05	2	113	2	21843653
Pubmed	Dual Inhibition of CDK12/CDK13 Targets Both Tumor and Immune Cells in Ovarian Cancer.	CDK12 CDK13	1.05e-05	2	113	2	35857807
Pubmed	Effects of deletion of gria1 or gria2 genes encoding glutamatergic AMPA-receptor subunits on place preference conditioning in mice.	GRIA1 GRIA2	1.05e-05	2	113	2	15619119
Pubmed	Cortical Synaptic AMPA Receptor Plasticity during Motor Learning.	GRIA1 GRIA2	1.05e-05	2	113	2	31901303
Pubmed	The glycolytic enzyme phosphofructokinase-1 assembles into filaments.	PFKL PFKM	1.05e-05	2	113	2	28646105
Pubmed	AMPA glutamate receptors and their flip and flop mRNAs in human hippocampus.	GRIA1 GRIA2	1.05e-05	2	113	2	7919190
Pubmed	Nanoscale Mobility of the Apo State and TARP Stoichiometry Dictate the Gating Behavior of Alternatively Spliced AMPA Receptors.	GRIA1 GRIA2	1.05e-05	2	113	2	31053408
Pubmed	AMPAR trafficking in synapse maturation and plasticity.	GRIA1 GRIA2	1.05e-05	2	113	2	23475111
Pubmed	Synthetic peptides from the N-domains of CEACAMs activate neutrophils.	CEACAM3 CEACAM6	1.05e-05	2	113	2	12005421
Pubmed	Expression of alternatively-spliced glutamate receptors in human hippocampus.	GRIA1 GRIA2	1.05e-05	2	113	2	8420792
Pubmed	CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1.	CDK12 CDK13	1.05e-05	2	113	2	20952539
Pubmed	GluA2-lacking AMPA receptors in hippocampal CA1 cell synapses: evidence from gene-targeted mice.	GRIA1 GRIA2	1.05e-05	2	113	2	22375105
Pubmed	The C-terminal tails of endogenous GluA1 and GluA2 differentially contribute to hippocampal synaptic plasticity and learning.	GRIA1 GRIA2	1.05e-05	2	113	2	29230056
Pubmed	Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome.	DVL1P1 DVL1	1.05e-05	2	113	2	8644734
Pubmed	Chronic stress-induced dendritic reorganization and abundance of synaptosomal PKA-dependent CP-AMPA receptor in the basolateral amygdala in a mouse model of depression.	GRIA1 GRIA2	1.05e-05	2	113	2	28336441
Pubmed	MAP3Ks as central regulators of cell fate during development.	MAP3K9 MAP3K10 MAP3K15	1.48e-05	15	113	3	18855897
Pubmed	PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking.	GRIA1 GRIA2 AP2A2	1.81e-05	16	113	3	16055064
Pubmed	Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes.	ACLY PFKM MAP3K10 TJP2	2.00e-05	49	113	4	19019082
Pubmed	Prenatal expression of D-aspartate oxidase causes early cerebral D-aspartate depletion and influences brain morphology and cognitive functions at adulthood.	GRIA1 GRIA2 GRIK1	2.20e-05	17	113	3	32185508
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PHYKPL GRIK1 MCCC2 ADGRV1 PFKL ME2 CDC42BPB SLC7A1 KLHL9 PNPLA6 CDK13 LOXL2 SERINC5 PNPLA7 LRBA PATJ	2.59e-05	1489	113	16	28611215
Pubmed	NMDAR-dependent presynaptic homeostasis in adult hippocampus: Synapse growth and cross-modal inhibitory plasticity.	GRIA1 GRIA2	3.13e-05	3	113	2	36070750
Pubmed	Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches.	PFKL PFKM	3.13e-05	3	113	2	33141153
Pubmed	Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to antipsychotic treatment in patients with schizophrenia.	GRIA1 GRIA2	3.13e-05	3	113	2	22094384
Pubmed	An inhalation anaesthesia approach for neonatal mice allowing streamlined stereotactic injection in the brain.	GRIA1 GRIA2	3.13e-05	3	113	2	32569783
Pubmed	Long-term potentiation reconstituted with an artificial TARP/PSD-95 complex.	GRIA1 GRIA2	3.13e-05	3	113	2	36223737
Pubmed	Persistent synaptic scaling independent of AMPA receptor subunit composition.	GRIA1 GRIA2	3.13e-05	3	113	2	23864664
Pubmed	Aggravated Lyme carditis in CD11a-/- and CD11c-/- mice.	ITGAL ITGAX	3.13e-05	3	113	2	16239568
Pubmed	FXR1P limits long-term memory, long-lasting synaptic potentiation, and de novo GluA2 translation.	GRIA1 GRIA2	3.13e-05	3	113	2	25456134
Pubmed	The Na+/H+ exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE3 upregulation.	SLC9A1 SLC9A2	3.13e-05	3	113	2	14962844
Pubmed	AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions.	GRIA1 GRIA2	3.13e-05	3	113	2	34426577
Pubmed	Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to treatment in patients with major depressive disorder.	GRIA1 GRIA2	3.13e-05	3	113	2	22057216
Pubmed	Phosphofructokinase (PFK) isozymes in man. I. Studies of adult human tissues.	PFKL PFKM	3.13e-05	3	113	2	156693
Pubmed	Mice lacking both mixed-lineage kinase genes Mlk1 and Mlk2 retain a wild type phenotype.	MAP3K9 MAP3K10	3.13e-05	3	113	2	18414056
Pubmed	NHE1, NHE2, and NHE4 contribute to regulation of cell pH in T84 colon cancer cells.	SLC9A1 SLC9A2	3.13e-05	3	113	2	17943310
Pubmed	Functional expression of human mutant phosphofructokinase in yeast: genetic defects in French Canadian and Swiss patients with phosphofructokinase deficiency.	PFKL PFKM	3.13e-05	3	113	2	7825568
Pubmed	Isozymes of human phosphofructokinase in blood cells and cultured cell lines: molecular and genetic evidence for a trigenic system.	PFKL PFKM	3.13e-05	3	113	2	6451249
Pubmed	Chromosomal location of the genes encoding the leukocyte adhesion receptors LFA-1, Mac-1 and p150,95. Identification of a gene cluster involved in cell adhesion.	ITGAL ITGAX	3.13e-05	3	113	2	3284962
Pubmed	BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors.	CDK12 CHEK1	3.13e-05	3	113	2	29025359
Pubmed	Calcineurin homologous protein as an essential cofactor for Na+/H+ exchangers.	SLC9A1 SLC9A2	3.13e-05	3	113	2	11350981
Pubmed	Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage.	GRIA1 GRIA2	3.13e-05	3	113	2	15144856
Pubmed	Antibody ligation of CEACAM1, CEACAM3, and CEACAM6, differentially enhance the cytokine release of human neutrophils in responses to Candida albicans.	CEACAM3 CEACAM6	3.13e-05	3	113	2	34847408
Pubmed	Critical role for NHE1 in intracellular pH regulation in pancreatic acinar cells.	SLC9A1 SLC9A2	3.13e-05	3	113	2	12842825
Pubmed	Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome.	GRIA1 GRIA2	3.13e-05	3	113	2	17507556
Pubmed	VPS35-deficiency results in an impaired AMPA receptor trafficking and decreased dendritic spine maturation.	GRIA1 GRIA2	3.13e-05	3	113	2	26521016
Pubmed	Isozymes of human phosphofructokinase: identification and subunit structural characterization of a new system.	PFKL PFKM	3.13e-05	3	113	2	6444721
Pubmed	Expression, immunolocalization, and functional activity of Na+/H+ exchanger isoforms in mouse endometrial epithelium.	SLC9A1 SLC9A2	3.13e-05	3	113	2	12493726
Pubmed	CD11a, CD11c, and CD18 gene polymorphisms and susceptibility to Behçet's disease in Koreans.	ITGAL ITGAX	3.13e-05	3	113	2	25155097
Pubmed	Glutamate receptor subunit 3 is modified by site-specific limited proteolysis including cleavage by gamma-secretase.	GRIA1 GRIA2	3.13e-05	3	113	2	12700243
Pubmed	Ras and Rap Signal Bidirectional Synaptic Plasticity via Distinct Subcellular Microdomains.	GRIA1 GRIA2	3.13e-05	3	113	2	29706584
Pubmed	CD11a regulates effector CD8 T cell differentiation and central memory development in response to infection with Listeria monocytogenes.	ITGAL ITGAX	3.13e-05	3	113	2	23357382
Cytoband	6q22	PREP DSE	1.67e-04	8	113	2	6q22
Cytoband	6p21	PRSS16 ITPR3 GTPBP2	3.86e-04	57	113	3	6p21
GeneFamily	Kelch like\|BTB domain containing	KLHL6 KLHL40 IPP KLHL9 KLHL7 KLHL36	3.58e-08	42	83	6	617
GeneFamily	Patatin like phospholipase domain containing	PNPLA6 PNPLA8 PNPLA7	1.09e-05	10	83	3	466
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL6 KLHL40 IPP KLHL9 KLHL7 KLHL36	3.50e-05	134	83	6	861
GeneFamily	Glutamate ionotropic receptor AMPA type subunits	GRIA1 GRIA2	1.24e-04	4	83	2	1200
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K9 MAP3K10 MAP3K15	1.76e-04	24	83	3	654
GeneFamily	PDZ domain containing	MAGIX DVL1 USH1C TJP2 PATJ	6.74e-04	152	83	5	1220
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PFKM ITPR3 SLC9A1 HCFC1 PPP1R42	1.47e-03	181	83	5	694
GeneFamily	CD molecules\|Integrin alpha subunits	ITGAL ITGAX	3.04e-03	18	83	2	1160
GeneFamily	Aldehyde dehydrogenases	ALDH1L2 ALDH16A1	3.38e-03	19	83	2	398
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA4G SEMA4A	3.75e-03	20	83	2	736
GeneFamily	CD molecules\|V-set domain containing\|Immunoglobulin like domain containing\|Carcinoembryonic antigen related cell adhesion molecule family	CEACAM3 CEACAM6	5.38e-03	24	83	2	906
GeneFamily	Cyclin dependent kinases	CDK12 CDK13	6.30e-03	26	83	2	496
GeneFamily	Adenosine receptors\|V-set domain containing	CEACAM3 CEACAM6 NCR3 JAM3	6.74e-03	163	83	4	590
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	CEACAM3 CEACAM6 ITGAL ITGAX NCR3 ADGRE5	9.51e-03	394	83	6	471
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8\|TCGA-Bladder / Sample_Type by Project: Shred V9	TANC2 GPLD1 DNAJC16 MCCC2 SLC9A2 TOP2B	2.34e-06	150	113	6	1aa9320d97ff10994ea024751790524fe133aba9
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ENGASE ACOT4 ITGAL PNPLA6 SVIL ADGRE5	4.35e-06	167	113	6	1cd9e2af85c6c5b9e1d88991c87ac6980b387243
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	KLHL6 MAGIX XDH ITGAX ITPR3	5.69e-06	100	113	5	b4e8f3cbb5023d2227f43e683967ec2f848648f1
ToppCell	droplet-Lung-nan-3m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 ITGAX KLHL9 PNPLA8 PNPLA7 PATJ	7.58e-06	184	113	6	3261d767d5e3d9e9fbac22ad73ca14e44beed89c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK3 FA2H ADGRV1 ITPR3 ATP2C2 PATJ	9.66e-06	192	113	6	d3634574b2e8d2ded6446969361b70761b331aea
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD9 CUL9 GRIA2 SYNDIG1 PNPLA6	5.34e-05	159	113	5	4000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD9 CUL9 GRIA2 SYNDIG1 PNPLA6	5.34e-05	159	113	5	7619d0d49738dd08daf01b42664691a5323aa793
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	FA2H ITPR3 SLC7A1 ADGRE5 HCFC1	5.34e-05	159	113	5	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RRAS2 ITGAL ITGAX SEMA4A DSE	6.19e-05	164	113	5	9fed5df40f50bde35db8bf89c291cbdc0e104112
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RRAS2 ITGAL ITGAX SEMA4A DSE	6.19e-05	164	113	5	e712d6b89461f741dbd773ba9a27ecaddf97cbaa
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TDRD9 CUL9 GRIA2 SYNDIG1 PNPLA6	6.55e-05	166	113	5	bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	DOCK3 GPR155 SLC25A18 SLC9A1 FBXO31	6.55e-05	166	113	5	8d5d09f25e8903d481c2097fed435e69d42ccdb5
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TDRD9 CUL9 GRIA2 SYNDIG1 PNPLA6	6.55e-05	166	113	5	5e3b998d740b24f790fad37350d704ca0ea10b77
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PRSS16 CHEK1 TJP2 LTK JAM3	7.75e-05	172	113	5	d65ffff3e341af34a043a0d802d7ba4b69de36e9
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENGASE USH1C ITGAL ITPR3 ATP2C2	8.40e-05	175	113	5	f7cd2ef79d91d64976fcdb5f1e7343b24ba27456
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TCAF2 ITGAL NCR3 RTP5 ADGRE5	9.10e-05	178	113	5	a96941fef62c2f4533c557ef825ae3265f8f52db
ToppCell	Globus_pallidus-Macroglia\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FA2H RHBDL2 TJP2 SERINC5 JAM3	9.35e-05	179	113	5	ab50f711b004b96107f813c9a2526ec21d1c8027
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLHL6 ITGAL ME2 PNPLA7 SEMA4A	9.60e-05	180	113	5	cc31d2cd06161300b91b17a67bb432b75f0d719b
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLHL6 ITGAL ME2 PNPLA7 SEMA4A	1.01e-04	182	113	5	94d061b7b5ebbfc564c644bc8b2d52341927145d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 SLC25A18 GRIA1 SYNDIG1 PFKM	1.04e-04	183	113	5	25c96df8ea0c7bbedbb7699ee84ad6234d19cba8
ToppCell	droplet-Lung-nan-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 ITGAX KLHL9 PNPLA7 PATJ	1.04e-04	183	113	5	ec3c05b9ce1e0fbb720e0dea41f1e28fd3fd878f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 SLC25A18 GRIA1 SYNDIG1 PNPLA7	1.04e-04	183	113	5	99bb4ceb92f6467f2359a42ab2cff6df18825a30
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ADGRV1 ITPR3 ATP2C2 MAP3K9 PATJ	1.06e-04	184	113	5	fa4915b0498f3069fd5ef497286445528f75187e
ToppCell	droplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 GPR155 ITGAX KLHL9 PATJ	1.12e-04	186	113	5	f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCell	droplet-Lung-nan-21m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 GPR155 ITGAX KLHL9 PATJ	1.12e-04	186	113	5	8f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FA2H ADGRV1 ATP2C2 MAP3K9 PATJ	1.15e-04	187	113	5	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ABCA3 CEACAM6 ADGRV1 ATP2C2 PATJ	1.18e-04	188	113	5	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK3 CPXM2 ADGRV1 ATP2C2 PATJ	1.18e-04	188	113	5	0d86044bc340e3efb90d0022dd299873639d831c
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DOCK3 CPXM2 ADGRV1 ATP2C2 PATJ	1.18e-04	188	113	5	beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAX KLHL9 PNPLA8 PNPLA7 PATJ	1.21e-04	189	113	5	287e59104687fe1665232c52993889f0f2c97f17
ToppCell	tumor_Lung-B_lymphocytes-GC_B_cells_in_the_LZ\|B_lymphocytes / Location, Cell class and cell subclass	KLHL6 ATP5MC3 RRAS2 LOXL2 SEMA4A	1.24e-04	190	113	5	bfb16efb23add53eebabc8e48f20c96994ec01da
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK3 ADGRV1 ATP2C2 MAP3K9 PATJ	1.24e-04	190	113	5	625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK3 SH3TC2 FA2H GRIK1 JAM3	1.24e-04	190	113	5	e2481bd5166fde2cdc0c3824894f2bccb8294fdd
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	TANC2 ABCA3 ADGRV1 ATP2C2 PATJ	1.27e-04	191	113	5	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA3 ADGRV1 ITPR3 ATP2C2 PATJ	1.27e-04	191	113	5	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 SLC25A18 PFKM PNPLA7 SEMA4A	1.30e-04	192	113	5	261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	ABCA3 ADGRV1 ITPR3 ATP2C2 PATJ	1.30e-04	192	113	5	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA3 ADGRV1 ITPR3 ATP2C2 PATJ	1.30e-04	192	113	5	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK3 RRAS2 SYNDIG1 SVIL PATJ	1.33e-04	193	113	5	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-suprabasal_differentiating\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCAF2 SEMA4G ALDH1L2 LOXL2 TOP2B	1.33e-04	193	113	5	49f4fbec91acda4727703e0e359ed780eefb8a22
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	TANC2 ABCA3 ADGRV1 ITPR3 ATP2C2	1.33e-04	193	113	5	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA3 ADGRV1 ITPR3 ATP2C2 PATJ	1.33e-04	193	113	5	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TANC2 GPLD1 ABCA3 ADGRV1 PATJ	1.36e-04	194	113	5	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DOCK3 CPXM2 ADGRV1 MAP3K9 PATJ	1.40e-04	195	113	5	d67a2b489c29bfd575751c13d2a5b1efdec5240a
ToppCell	10x5'v1-week_14-16-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	UBXN1 CDK13 SERINC5 PNPLA7 TOP2B	1.40e-04	195	113	5	dc84a910b6f6eb9994cd683aa4fd813a82198e5f
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABCA3 ADGRV1 ATP2C2 LRBA PATJ	1.40e-04	195	113	5	9406866f99555198a9be311fbd65751b70f35446
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	ENGASE DNAJC16 SLC7A1 LOXL2 SEMA4A	1.43e-04	196	113	5	7be50b9156394dea44d7b8b476d4dd516abfafae
ToppCell	Sepsis-URO-Lymphocyte-T/NK-CD8+_T_naive\|URO / Disease, condition lineage and cell class	GPLD1 GPR155 PRSS16 SERINC5 LRBA	1.50e-04	198	113	5	c07426d4119b53e58eb5f448ae364f47cac1fc5c
ToppCell	Bronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Mucous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PRSS16 CEACAM6 GRIA2 ALDH1L2 PNPLA7	1.53e-04	199	113	5	eb2d1b7e875c5bf833e7a80b43282e12893c34e9
ToppCell	Frontal_cortex-Neuronal\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TANC2 DOCK3 GRIA1 GRIA2 MAP3K9	1.53e-04	199	113	5	f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCell	Macroglial-Oligodendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ANO4 SH3TC2 FA2H SYNDIG1 JAM3	1.57e-04	200	113	5	4dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	ACLY GRIA2 PFKM PREP SERINC5	1.57e-04	200	113	5	e9eb348a66011d8aace4331f84690ae27cb0d061
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA3 CEACAM6 ADGRV1 ITPR3 ATP2C2	1.57e-04	200	113	5	65c83a3f6ee2a10bcb5b95076696232c6373a7b4
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ABCA3 CEACAM6 ADGRV1 ITPR3 ATP2C2	1.57e-04	200	113	5	40e969883bc302e8fbc6b6ab9814529dc1472902
ToppCell	Macroglial-Oligodendrocytes-OPALIN--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ANO4 SH3TC2 FA2H SYNDIG1 JAM3	1.57e-04	200	113	5	26b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-AT2-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ABCA3 CEACAM6 ADGRV1 ITPR3 ATP2C2	1.57e-04	200	113	5	ad9cdc82a647d379abc713a56db0e11bb6494106
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	ACLY GRIA2 PFKM PREP SERINC5	1.57e-04	200	113	5	09fd3cb31bcc02444f1045f01fe39bce09359d35
ToppCell	Macroglial-Oligodendrocytes-OPALIN---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ANO4 SH3TC2 FA2H SYNDIG1 JAM3	1.57e-04	200	113	5	1314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCell	Macroglial-Oligodendrocytes-OPALIN-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ANO4 SH3TC2 FA2H SYNDIG1 JAM3	1.57e-04	200	113	5	8b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCell	Macroglial-Oligodendrocytes-OPALIN----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ANO4 SH3TC2 FA2H SYNDIG1 JAM3	1.57e-04	200	113	5	272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCell	Macroglial-Oligodendrocytes-OPALIN\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ANO4 SH3TC2 FA2H SYNDIG1 JAM3	1.57e-04	200	113	5	5f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-MAIT\|ICU-NoSEP / Disease, condition lineage and cell class	CCNL2 DVL1 ACOT4 NCR3 LTK	1.57e-04	200	113	5	4f03b5f4110ed1637ffe17cb6ff309265a3af9a8
Drug	L-Glutamic Acid	SLC25A18 GRIA1 GRIA2 GRIK1 OPLAH DNPEP	1.06e-06	68	112	6	DB00142
Drug	thio-ATPA	GRIA1 GRIA2 GRIK1	4.00e-06	7	112	3	CID005289517
Drug	hydroxyrubicin	ABCB5 XDH TOP2B ABCC10	4.57e-06	23	112	4	CID000072398
Drug	homoibotenic acid	GRIA1 GRIA2 GRIK1	6.37e-06	8	112	3	CID000194385
Drug	1m5b	GRIA1 GRIA2 GRIK1	9.53e-06	9	112	3	CID000447081
Drug	Ly294486	GRIA1 GRIA2 GRIK1	9.53e-06	9	112	3	CID005311255
Drug	LY339434	GRIA1 GRIA2 GRIK1	9.53e-06	9	112	3	CID006324635
Drug	1-methoxyphenazine	XDH PFKM PNPLA6	1.36e-05	10	112	3	CID000076137
Drug	Benzoates	GRIA1 GRIA2 GRIK1	1.36e-05	10	112	3	ctd:D001565
Drug	4-methylglutamic acid	GRIA1 GRIA2 GRIK1 DSE	1.58e-05	31	112	4	CID000005365
Drug	J-ST	GRIA1 GRIA2 GRIK1	1.86e-05	11	112	3	CID005288655
Drug	YM872	GRIA1 GRIA2 GRIK1	1.86e-05	11	112	3	CID000148200
Drug	sym 2206	GRIA1 GRIA2 GRIK1	1.86e-05	11	112	3	CID005039877
Drug	1-aminoindan-1,5-dicarboxylic acid	GPLD1 GRIA1 GRIA2 GRIK1	2.03e-05	33	112	4	CID000002071
Drug	lamotrigine	GRIA1 GRIA2 GRIK1 ITPR3 LOXL2 PKD1	2.37e-05	116	112	6	CID000003878
Drug	4-bromo-2-methylbenzoic acid	SLC9A1 SLC9A2	2.40e-05	2	112	2	CID000099570
Drug	2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid	GRIA1 GRIA2	2.40e-05	2	112	2	ctd:C474829
Drug	2,3,5-tri-O-benzyl-D-arabinofuranose	PFKL PFKM	2.40e-05	2	112	2	CID000255457
Drug	4-bromohomoibotenic acid	GRIA1 GRIA2	2.40e-05	2	112	2	ctd:C023366
Drug	Atpa	GRIA1 GRIA2 GRIK1	2.47e-05	12	112	3	CID000002252
Drug	C-X6	GRIA1 GRIA2 GRIK1	2.47e-05	12	112	3	CID005288002
Drug	felbamate	GRIA1 GRIA2 GRIK1 ADGRV1 ADGRE5	2.47e-05	70	112	5	CID000003331
Drug	kainite	GRIA1 GRIA2 GRIK1 MAP3K10	2.58e-05	35	112	4	CID000164810
Drug	AC1LAIW3	ABCB5 CHEK1 MAP3K9 MAP3K10 TOP2B	2.83e-05	72	112	5	CID000469261
Drug	Naspm	GRIA1 GRIA2 GRIK1	3.20e-05	13	112	3	CID000129695
Drug	benzbromarone	ABCB5 XDH TOP2B ABCC10	3.23e-05	37	112	4	CID000002333
Drug	BAPTA	GPLD1 GRIA1 GRIA2 GRIK1 ITPR3 SLC9A1 ATP2C2 LRBA DSE	3.26e-05	324	112	9	CID000104751
Drug	quinoxaline-2,3-dione	GRIA1 GRIA2 GRIK1	4.05e-05	14	112	3	CID011469229
Drug	Tetrodotoxin	GRIA1 GRIA2 SLC9A1 RHBDL2	4.42e-05	40	112	4	ctd:D013779
Drug	pentylenetetrazol	ACLY GRIA1 GRIA2 GRIK1 ADGRV1 ADGRE5	4.50e-05	130	112	6	CID000005917
Drug	ara-Hx	ABCB5 XDH GRIA2 GRIK1 PFKL PFKM PNPT1	4.82e-05	193	112	7	CID000000804
Drug	thiokynurenic acid	GRIA1 GRIA2 GRIK1	5.05e-05	15	112	3	CID003035667
Drug	Budesonide [51333-22-3]; Up 200; 9.2uM; PC3; HT_HG-U133A	ABCA3 CEACAM3 PIPOX XDH SEMA4G MAP3K9 HCFC1	5.15e-05	195	112	7	6330_UP
Drug	Zuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A	CEACAM6 CUL9 SLC7A1 SLC9A2 SUV39H1 ADGRE5 PATJ	5.32e-05	196	112	7	7356_DN
Drug	Vincamine [1617-90-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A	XDH UBXN1 AP2A2 CDK13 ZSCAN2 HCFC1 DNPEP	5.49e-05	197	112	7	2327_DN
Drug	Deferoxamine mesylate [138-14-7]; Down 200; 6uM; MCF7; HT_HG-U133A	YIPF4 CEACAM6 GTPBP2 AP2A2 SUV39H1 SVIL HCFC1	5.49e-05	197	112	7	3417_DN
Drug	Iopamidol [60166-93-0]; Down 200; 5.2uM; MCF7; HT_HG-U133A	CEACAM6 SLC7A1 SLC9A1 AP2A2 KCNF1 SUV39H1 ADGRE5	5.67e-05	198	112	7	7189_DN
Drug	decahydroisoquinoline	GRIA1 GRIA2 GRIK1	6.19e-05	16	112	3	CID000097812
Drug	fluoroanilinoazatoxin	ABCB5 TOP2B	7.17e-05	3	112	2	CID000378896
Drug	NSC688503	ABCB5 TOP2B	7.17e-05	3	112	2	CID000390744
Drug	BIBW22BS	ABCB5 TOP2B	7.17e-05	3	112	2	CID000132088
Drug	3-methylsulfonyl-4-piperidinobenzoyl guanidine	SLC9A1 SLC9A2	7.17e-05	3	112	2	ctd:C074107
Drug	AC1L977H	PFKL PFKM	7.17e-05	3	112	2	CID000439366
Drug	AC1L1H8N	GRIA2 GRIK1	7.17e-05	3	112	2	CID000004023
Drug	N-desalkyl-2-oxoquazepam	GRIA1 GRIK1	7.17e-05	3	112	2	CID000004540
Drug	methylazatoxin	ABCB5 TOP2B	7.17e-05	3	112	2	CID000148162
Drug	Wp159	ABCB5 TOP2B	7.17e-05	3	112	2	CID003060549
Drug	5-N-(methyl-propyl)amiloride	SLC9A1 SLC9A2	7.17e-05	3	112	2	CID000193326
Drug	phenobarbital	DOCK3 ABCA3 ABCB5 PIPOX GRIA1 GRIA2 GRIK1 ACOT4 SLC9A2	7.35e-05	360	112	9	CID000004763
Drug	7-Cl-Thio-Kyna	GRIA1 GRIA2 GRIK1	7.49e-05	17	112	3	CID003035668
Drug	phosphoenolpyruvate	ACLY MCCC2 PFKL PFKM ME2 LRBA OPLAH	8.21e-05	210	112	7	CID000001005
Drug	AC1Q5UBL	GRIA1 GRIA2 GRIK1 ADGRV1 SLC9A1 ADGRE5	8.59e-05	146	112	6	CID000005466
Drug	MNQX	GRIA1 GRIA2 GRIK1	8.96e-05	18	112	3	CID000130818
Drug	avermectin	ABCB5 GRIA1 GRIA2 GRIK1	9.14e-05	48	112	4	CID006450460
Drug	Phosphoryl	GPLD1 PFKL PFKM ITPR3 CDK13 ATP2C2 LRBA	9.51e-05	215	112	7	CID006857426
Drug	1xa5	XDH GRIA1 GRIA2 GRIK1 ME2	9.70e-05	93	112	5	CID000157684
Drug	5,7-dichlorokynurenic acid	SLC25A18 GRIA1 GRIA2 GRIK1	9.91e-05	49	112	4	CID000001779
Drug	caffeine	GPLD1 XDH GRIA1 GRIA2 GRIK1 CHEK1 ITPR3 ATP2C2 PKD1 LRBA TOP2B	1.04e-04	562	112	11	CID000002519
Drug	LY382884	GRIA1 GRIA2 GRIK1	1.06e-04	19	112	3	CID000656723
Drug	phenazine	PIPOX XDH GRIK1 MCCC2 TOP2B	1.07e-04	95	112	5	CID000004757
Drug	IDRA 21	GRIA1 GRIA2 GRIK1	1.24e-04	20	112	3	CID000003688
Drug	AC1N8N2J	GRIA1 GRIA2 GRIK1	1.24e-04	20	112	3	CID004346372
Drug	phytate	XDH GRIA1 GRIA2 PFKL ITPR3 AP2A2	1.37e-04	159	112	6	CID000000890
Drug	sunifiram	GRIA1 GRIA2	1.43e-04	4	112	2	CID004223812
Drug	4-(chloromethyl)-3-methoxy-5-methylisoxazole	GRIA1 GRIA2	1.43e-04	4	112	2	CID011105661
Drug	BBR 2378	ABCB5 TOP2B	1.43e-04	4	112	2	CID000219053
Drug	3-isoxazolol	GRIA1 GRIA2	1.43e-04	4	112	2	CID009964065
Drug	9-methylphenazine-1-carboxylic acid	ABCB5 TOP2B	1.43e-04	4	112	2	CID004037810
Drug	3-pyridazinol 1-oxide	GRIA1 GRIA2	1.43e-04	4	112	2	CID000574311
Drug	Uridine diphosphate 2-deoxyglucose	PFKL PFKM	1.43e-04	4	112	2	CID000165519
Drug	NK-252	ABCB5 TOP2B	1.43e-04	4	112	2	CID000130889
Drug	CX546	GRIA1 GRIA2 GRIK1	1.44e-04	21	112	3	CID000002890
Drug	AC1L1B62	GRIA1 GRIA2 GRIK1	1.44e-04	21	112	3	CID000001299
Drug	NS 102	GRIA1 GRIA2 GRIK1	1.67e-04	22	112	3	CID005282252
Drug	CX516	GRIA1 GRIA2 GRIK1	1.67e-04	22	112	3	CID000148184
Drug	YM90K	GRIA1 GRIA2 GRIK1	1.91e-04	23	112	3	CID005486547
Drug	GYKI 52466	GRIA1 GRIA2 GRIK1 ADGRE5	1.92e-04	58	112	4	CID000003538
Drug	ammonia	PIPOX XDH GRIK1 PFKL PFKM ME2 SLC9A1 SLC9A2 LOXL2 PKD1	2.11e-04	509	112	10	CID000000222
Drug	pD 8	GRIA1 GRIA2 GRIK1	2.18e-04	24	112	3	CID000656948
Drug	CGP 39653	GRIA1 GRIA2 GRIK1	2.18e-04	24	112	3	CID006437837
Drug	3,5-dihydroxyphenylglycine	GPLD1 GRIA1 GRIA2 GRIK1	2.19e-04	60	112	4	CID000108001
Drug	AC1L1A5Z	GRIA1 GRIA2 PFKL PFKM ARCN1	2.23e-04	111	112	5	CID000000850
Drug	3,7-diaminoheptan-2-one	CEACAM3 GRIA1 GRIK1 ITGAX	2.33e-04	61	112	4	CID004477684
Drug	AC1L1YEG	GRIA1 GRIA2	2.38e-04	5	112	2	CID000063114
Drug	Chicago acid	GRIA1 GRIA2	2.38e-04	5	112	2	CID000065740
Drug	CHEBI:570577	GRIA1 GRIA2	2.38e-04	5	112	2	CID011334126
Drug	1-BCP	GRIA1 GRIA2	2.38e-04	5	112	2	CID000001370
Drug	irampanel	GRIA1 GRIA2	2.38e-04	5	112	2	CID003038472
Drug	LY395153	GRIA1 GRIA2	2.38e-04	5	112	2	CID000656707
Drug	beta-N-oxalylaminoalanine	GRIA1 GRIA2	2.38e-04	5	112	2	CID000107978
Drug	5-h PCA	GRIA1 GRIA2	2.38e-04	5	112	2	CID000129091
Drug	Ns102	GRIA1 GRIA2 GRIK1	2.46e-04	25	112	3	CID005311098
Drug	gavestinel	GRIA1 GRIA2 GRIK1	2.46e-04	25	112	3	CID006450546
Drug	etiracetam	ABCA3 GRIA1 GRIA2 PFKL	2.48e-04	62	112	4	CID000059708
Drug	Withaferin A [5119-48-2]; Down 200; 1uM; PC3; HT_HG-U133A	SH3TC2 CUL9 KLHL9 LOXL2 ATP2C2 DNPEP	2.61e-04	179	112	6	4554_DN
Drug	AP-7	GRIA1 GRIA2 GRIK1 ADGRE5	2.64e-04	63	112	4	CID000003122
Drug	strychnine HCl	GRIA1 GRIA2 GRIK1 ADGRV1 PFKL TOP2B	2.77e-04	181	112	6	CID000005304
Drug	phencyclidine	SLC25A18 GRIA1 GRIA2 GRIK1 PFKL PFKM	2.77e-04	181	112	6	CID000006468
Drug	H 85	GPLD1 ABCB5 LRBA	2.77e-04	26	112	3	CID006439306
Drug	AC1L7AJI	ABCB5 CEACAM3 CHEK1 ITGAX CDK13 TOP2B ABCC10	2.78e-04	256	112	7	CID000003750
Disease	neurodegenerative disease (implicated_via_orthology)	DVL1P1 DVL1 GRIA1 GRIA2 GRIK1 PNPLA6 PNPLA7	1.33e-06	145	111	7	DOID:1289 (implicated_via_orthology)
Disease	glycogen storage disease (implicated_via_orthology)	PFKL PFKM	8.37e-05	4	111	2	DOID:2747 (implicated_via_orthology)
Disease	DiGeorge syndrome (is_implicated_in)	DVL1P1 DVL1	1.39e-04	5	111	2	DOID:11198 (is_implicated_in)
Disease	nephrolithiasis (implicated_via_orthology)	SLC9A1 SLC9A2	1.39e-04	5	111	2	DOID:585 (implicated_via_orthology)
Disease	Hyperuricemia	XDH ALDH16A1	2.91e-04	7	111	2	C0740394
Disease	Dystonia	FOXRED1 FA2H PNPT1 GTPBP2	3.18e-04	86	111	4	C0013421
Disease	blindness (implicated_via_orthology)	PNPLA6 PNPLA7	3.87e-04	8	111	2	DOID:1432 (implicated_via_orthology)
Disease	cerebellar ataxia (implicated_via_orthology)	PNPLA6 PNPLA7	3.87e-04	8	111	2	DOID:0050753 (implicated_via_orthology)
Disease	Gout	XDH ALDH16A1	4.96e-04	9	111	2	C0018099
Disease	hearing impairment	ADGRV1 USH1C PNPT1 TJP2	5.22e-04	98	111	4	C1384666
Disease	hereditary spastic paraplegia (implicated_via_orthology)	ATP5MC3 PNPLA6 PNPLA7	5.73e-04	43	111	3	DOID:2476 (implicated_via_orthology)
Disease	Metastatic melanoma	MAP3K9 MAP3K10 MAP3K15	1.12e-03	54	111	3	C0278883
Disease	Spastic Paraplegia, Hereditary	FA2H PNPLA6	1.24e-03	14	111	2	C0037773
Disease	Seizures	TANC2 FA2H GRIA2 GRIK1 GTPBP2	1.43e-03	218	111	5	C0036572
Disease	central nervous system disease (implicated_via_orthology)	GRIA1 GRIA2	1.63e-03	16	111	2	DOID:331 (implicated_via_orthology)
Disease	inferior parietal cortex volume measurement	CPXM2 GRIK1	2.30e-03	19	111	2	EFO_0010307
Disease	urinary metabolite measurement	CDK12 DNAJC16 XDH ACOT4 DNPEP	2.38e-03	245	111	5	EFO_0005116
Disease	autism spectrum disorder (implicated_via_orthology)	ABCA3 ITPR3 ELP2 LRBA	2.64e-03	152	111	4	DOID:0060041 (implicated_via_orthology)
Disease	disease of metabolism (implicated_via_orthology)	PFKL PFKM	2.81e-03	21	111	2	DOID:0014667 (implicated_via_orthology)
Disease	interleukin 18 measurement	YIPF4 XDH MCCC2	2.98e-03	76	111	3	EFO_0004581
Disease	Nonsyndromic Deafness	ADGRV1 USH1C TJP2	3.57e-03	81	111	3	C3711374

Protein segments in the cluster

Peptide	Gene	Start	Entry
VGLQVGDEIVRINGY	USH1C	126	Q9Y6N9
KFDIIGIIGEGTYGQ	CDK12	726	Q9NYV4
GEGAYGEVQLAVNRV	CHEK1	16	O14757
VGFQQVGVETYGGGI	DNPEP	121	Q9ULA0
GQALELGYGLQVGTV	ALDH16A1	436	Q8IZ83
VGIGVAALIFGYIQI	ABCB5	111	Q2M3G0
GVKEGATLVYGGRQV	ALDH1L2	786	Q3SY69
GVENIGGIFIVLAAG	GRIK1	831	P39086
VYQIGVEDNGLLVGL	GTPBP2	101	Q9BX10
IFLAGIENEGGQVGL	ADGRE5	596	P48960
YFGEGEGGVRTIILT	ADGRV1	4581	Q8WXG9
GGEPGYIREGFLAVQ	ABCA3	201	Q99758
DIGIWYGILEGIGIL	ANO4	766	Q32M45
DIIGIIGEGTYGQVY	CDK13	706	Q14004
LVQYGRGQGVVIGTG	ATP2C2	251	O75185
IVGDVRGVGLFIGVD	PHYKPL	356	Q8IUZ5
GIGTVFGSLIIGYAR	ATP5MC3	91	P48201
VKVGGYILGEFGNLI	AP2A2	496	O94973
VLGGNLQGGELVVAY	CPXM2	511	Q8N436
ADAAGIIRYAIGVGL	ITGAX	276	P20702
QGLIYVIGGISNEGI	IPP	436	Q9Y573
YIGAALVLGGVDVTG	PSMB7	136	Q99436
GLGLLGLYINEDNVG	ITPR3	1921	Q14573
IKELIVVFGGGNEGI	HCFC1	41	P51610
YQQVGVAFVGGLILA	ABCC10	416	Q5T3U5
SIIGIGVGAGAYILS	NDRG3	131	Q9UGV2
ELVGEYGRGDLIGVV	PNPLA6	686	Q8IY17
GGELVLDGGNIDYVL	KLHL36	106	Q8N4N3
DRGLGGYGAALVVAV	SLC16A11	271	Q8NCK7
EEIIGVGGFGKVYRA	MAP3K10	101	Q02779
GKVYVIGGFDGLQRI	KLHL6	421	Q8WZ60
VELVRGYAGFGLTLG	MAGIX	126	Q9H6Y5
YVCRVEVLGLGVGTG	NCR3	106	O14931
RIFGYPVGIVGNNGV	MCCC2	361	Q9HCC0
EAVIYGDRLVQGGVI	GPR155	801	Q7Z3F1
ERVDGNSLIVGYVIG	CEACAM6	71	P40199
GAYIGEGRVEVLKNG	LOXL2	331	Q9Y4K0
GLGESLYILVGQQGE	LTK	151	P29376
FGEVYEGLVIGLPGD	LTK	521	P29376
SNVAGVFYILVGGLG	GRIA2	811	P42262
YGGLLNVVVDGLFII	FBXO31	156	Q5XUX0
KVYGILGAFIVGGLD	OR52A4P	201	A6NMU1
ALLVVGGFEAYEGVL	PFKL	491	P17858
QGLVIIGGFEAYTGG	PFKM	491	P08237
EEGGIFILHGNRGVY	GXYLT1	356	Q4G148
LGVGIGVVHAGYERR	DNAJC16	191	Q9Y2G8
GLQVGDVILEVNGYP	PDZD3	506	Q86UT5
GIAVIGNFLYVVGGQ	KLHL9	341	Q9P2J3
GQYLLTGGDRGVVVV	LRBA	2791	P50851
KNGVVFIRGEGVGAY	DSE	531	Q9UL01
GLGEALNSIYVVGGR	KLHL40	406	Q2TBA0
VGSIVYVLAGFQGVG	KLHL7	526	Q8IXQ5
YVLAGFQGVGRLGHI	KLHL7	531	Q8IXQ5
EVYDLNIGGIIGGVL	JAM3	236	Q9BX67
LGVDVQRGIGTAYKG	CDC42BPB	1086	Q9Y5S2
LVLGGGGYTVRNVAR	HDAC3	291	O15379
GEYGRGDLVGVVETL	PNPLA7	636	Q6ZV29
GGILAVANIRGGGEY	PREP	496	P48147
VGGTVFAGGLLGYVL	FA2H	296	Q7L5A8
GVIDAAVNGGIARYQ	DOCK3	1546	Q8IZD9
GIAQGVYFIGIGERI	SLC25A18	296	Q9H1K4
GSQGVLIGDRLYSGV	CCNL2	31	Q96S94
VVIVGGGVLGLSVAY	FOXRED1	66	Q96CU9
ERVDGNSLIVGYVIG	CEACAM3	71	P40198
VVVLLQGYAEPEGVG	MBLAC1	21	A4D2B0
TDGERILGLGDLGVY	ME2	161	P23368
GVEQVVLGLYIVRGD	LSM8	51	O95777
RYIDQQIQGGLIGGA	CUL9	1551	Q8IWT3
IVGQSNDRGDGGIYI	DVL1	266	O14640
YVGVDVFARGNVVGG	ENGASE	326	Q8NFI3
QVRVGEVGGNTLGFY	ELP2	331	Q6IA86
RAVIGSEFIGIGGNY	DPEP3	346	Q9H4B8
IVGQSNDRGDGGIYI	DVL1P1	266	P54792
VAGVFYILIGGLGLA	GRIA1	806	P42261
VYRDGVGDGQLQALL	PIWIL3	721	Q7Z3Z3
GVGAPVIGEIDGEYR	ARCN1	416	P48444
LEEIIGIGGFGKVYR	MAP3K9	146	P80192
VYVLQLIEGLQVVGG	PKD1	1626	P98161
LIEGLQVVGGGRYFP	PKD1	1631	P98161
ANGERVVLGKGTYGI	MAP3K15	651	Q6ZN16
EGVQALVGGYIGGLV	PNPLA8	296	Q9NP80
GGGVQYLLVGLSRLQ	RTP5	41	Q14D33
GLRVGLVYLAGVIAG	RHBDL2	156	Q9NX52
VSGLGVIGRDRYGVF	TOP2B	491	Q02880
ILDGVNVGRGYGLVE	SVIL	1726	O95425
IGTGVYVGVAVALIA	SYNDIG1	236	Q9H7V2
TLGGVVGYQVGLEKI	TDRD9	206	Q8NDG6
QLQEFVAEGGGLLIG	TCAF2	346	A6NFQ2
QKGIQLVGELIGQYG	OPLAH	931	O14841
LVGELIGQYGLDVVQ	OPLAH	936	O14841
LGGNYIAVIEGLEGL	PPP1R42	101	Q7Z4L9
YNGSLLLIVQDGVGG	SEMA4A	606	Q9H3S1
GQEKYRLVVVGGGGV	RRAS2	11	P62070
SRLVYQGSIGGIVGD	TANC2	1656	Q9HCD6
GVIYNLLGLALQGEG	SH3TC2	836	Q8TF17
GYRVLQVGNGVIVGA	ITGAL	46	P20701
GPVGAVRIGIIDGEY	PNPT1	186	Q8TCS8
YRVGEGITLNQVAVG	SUV39H1	166	O43463
YIDIGALNGIFVLGR	ACLY	1051	P53396
IDIFGIGGGLLEYRA	ACOT4	161	Q8N9L9
LFYDLVGGVERQGLV	CLXN	31	Q9HAE3
VGLRLAGGNDVGIFV	TJP2	521	Q9UDY2
VGQLIGLQGTYLGEK	ZSCAN2	206	Q7Z7L9
GQGGYRVGVDGLLVT	SEMA4G	606	Q9NTN9
ANFFVVGIGGVLIGI	SLC9A2	276	Q9UBY0
KDGQSLGIRIVGYVG	PATJ	371	Q8NI35
LGAGVYVLAGAVARE	SLC7A1	46	P30825
YVGAVGGFLFIGIQL	SERINC5	156	Q86VE9
VTSGLIGGEDGRVYV	GPLD1	746	P80108
DGIEELIGIYGISGQ	TTC41P	436	Q6P2S7
VALGGVLVGVVYGVI	SLC9A1	301	P19634
IDIGQVEGAFVQGLG	XDH	1191	P47989
GGIGFKYVALGDLII	UBIAD1	176	Q9Y5Z9
LYVELHRGEELGGGQ	UBXN1	241	Q04323
RGEVGLLDNSGGVIY	PIPOX	136	Q9P0Z9
IFLLARVLGGEVAYG	YIPF4	151	Q9BSR8
RVLGGEVAYGQVLGV	YIPF4	156	Q9BSR8
GALQALVGGVVQYDG	PRSS16	286	Q9NQE7
VVNVGGVRQVLYGDL	KCNF1	26	Q9H3M0